Mass spectrometer reagent adding device

Abstract

The utility model relates to a mass spectrometer reagent adding device which comprises a main injection part, an auxiliary injection part, a main injection pump part, a main sample injection capillary tube, an auxiliary pressure control pump part, an auxiliary capillary tube, a three-way valve part and a mass spectrum needle part. One end of the main sample injection capillary is connected with the main injection part; the auxiliary pressure control pump part is connected with the auxiliary injection part, and the auxiliary pressure control pump part is used for being started when the main injection pump part completes reagent pumping so as to recycle redundant reagents in the main injection part into the auxiliary injection part; one end of the auxiliary capillary is connected with the auxiliary injection part; the first end of the three-way valve is connected with the main sample injection capillary, and the second end of the three-way valve is connected with the auxiliary capillary; and the mass spectrum needle piece is connected with the third end of the three-way valve piece. The technical scheme has the beneficial technical effects that when the reagent is pumped, the end, connected with the mass spectrum needle, of the three-way valve piece is closed, so that the main injection piece is communicated with the auxiliary injection piece. And the auxiliary pressure control pump part operates, so that the reagent enters the auxiliary injection part more quickly.

Description

TECHNICAL FIELD

[0001] The utility model relates to mass spectrum analysis field, concretely relates to a mass spectrometer reagent adding device. BACKGROUND

[0002] Mass spectrometer technology originated in the late 19th century, and was initially used for isotope determination and inorganic element analysis. After half a century of development, commercial mass spectrometers appeared around 1950, and were gradually applied to the petroleum industry and chemical industry. With the advent of quadrupole, ion trap, time-of-flight and other mass analyzers, the performance and application range of mass spectrometers have been significantly improved.

[0003] The core technologies of mass spectrometers mainly include ion source, mass analyzer and detector. The ion source is responsible for ionizing molecules into charged ions, the mass analyzer separates according to the mass-to-charge ratio of the ions, and the detector records the number information of the ions. Different types of mass spectrometers differ in these three technologies, resulting in their unique performance characteristics. With the popularization and development of individualization and precision medicine concepts, the development and innovation of mass spectrometers have ushered in an era of rapid development.

[0004] The prior art CN116825606A provides an electrospray system based on a porous capillary structure for a mass spectrometer, which installs a sample injection syringe on an injection pump during implementation, and pumps the sample by pushing the syringe with the injection pump. However, at the moment when the pumping ends, there is still a certain air pressure in the syringe because the injection pump is still in the state of pushing the syringe. This leads to poor ionization effect in the final stage, which in turn affects the detection results to some extent.

[0005] Therefore, it is necessary to provide a mass spectrometer reagent adding device to solve the above technical problems. CONTENT OF THE UTILITY MODEL

[0006] Based on the above description, the utility model provides a mass spectrometer reagent adding device to solve the problem that the existing technology is prone to poor ionization effect in the pumping end stage, affecting the detection results.

[0007] The utility model discloses a technical scheme that solves the above technical problem is as follows: A mass spectrometer reagent adding device, including main injection part, vice injection part, main injection pump part, main sampling capillary, vice pressure control pump part, vice capillary, three -way valve spare and mass spectrum needle spare, the main injection pump part with the main injection part is connected, the main sampling capillary one end with the main injection part, the vice pressure control pump part with the vice injection part is connected, and the vice pressure control pump part is used for opening when the main injection pump part completes pumping reagent to recycle the reagent in the main injection part into the vice injection part, vice capillary one end with the vice injection part is connected, the three -way valve spare first end with the main sampling capillary is connected, and the second end of three -way valve spare is connected with vice capillary, and the mass spectrum needle spare is connected with the third end of three -way valve spare.

[0008] Further, the main injection pump part includes a main support frame, a main clamping part, and a main pump pressure part. The main support frame is provided with a main clamping slide and a main pump pressure slide. The main clamping part is connected to the main support frame. When the main clamping part is in a locked position, the main clamping part clamps the main injection part to fix the main injection part. When the main clamping part is in an unlocked position, the main clamping part is separated from the main injection part to disassemble the main injection part. The main pump pressure part is connected to the main support frame. When pumping reagent is needed, the main pump pressure part presses the pressing end of the main injection part to pump the reagent in the main injection part. When pumping reagent needs to be stopped, the main pump pressure part stops moving to stop the main injection part from pumping reagent.

[0009] Further, the main clamping part includes a main fixed clamping seat, a main clamping slide rod, a main movable clamping seat, and a main clamping drive part. The main fixed clamping seat is fixed to the main support frame. The main clamping slide rod is slidably connected to the main clamping slide. The main movable clamping seat is fixedly connected to the main clamping slide rod and slidably connected to the main fixed clamping seat. The main clamping drive part drives the main clamping slide rod to slide on the main clamping slide.

[0010] Further, the main clamping drive part includes a main clamping telescopic drive. The main clamping telescopic drive is provided with a fixed end and a telescopic end. The fixed end of the main clamping telescopic drive is fixed to the main support frame. The telescopic end of the main clamping telescopic drive is connected to a main connecting plate. The main connecting plate is fixedly connected to the main clamping slide rod.

[0011] Further, the main pump pressure piece comprises a main pump pressure push rod, a main pump pressure sliding block, a main pump pressure screw rod and a main pump pressure motor, the main pump pressure push rod is in sliding connection with the main fixed clamping seat, and the main pump pressure push rod is clamped with the telescopic end of the main injection member; one end of the main pump pressure sliding block is in sliding connection with the main pump pressure sliding channel, and the other end of the main pump pressure sliding block is fixedly connected with the main pump pressure push rod; the main pump pressure screw rod is rotatably connected to the main support frame body, and the main pump pressure sliding block is in threaded connection with the main pump pressure screw rod; the main pump pressure motor is provided with a fixed end and a rotating end, the fixed end of the main pump pressure motor is fixedly connected with the main support frame body, and the rotating end of the main pump pressure motor is fixedly connected with the main pump pressure screw rod.

[0012] Further, the auxiliary control pressure pump piece comprises an auxiliary support frame body, an auxiliary clamping member and an auxiliary control pressure member, the auxiliary support frame body is provided with an auxiliary clamping sliding channel and an auxiliary control pressure sliding channel; the auxiliary clamping member is connected to the auxiliary support frame body, and the auxiliary clamping member is configured to: when the auxiliary clamping member is in a locked position, the auxiliary clamping member is clamped with the auxiliary injection member to fix the auxiliary injection member; when the auxiliary clamping member is in an unlocked position, the auxiliary clamping member is separated from the auxiliary injection member to disassemble the auxiliary injection member; the auxiliary control pressure member is connected to the auxiliary support frame body, and the auxiliary control pressure member is configured to: before pumping reagents, the auxiliary control pressure member is in a locked position to limit the telescopic end of the auxiliary injection member in a compressed state; when pumping reagents is completed, the auxiliary control pressure member is in an unlocked position to make the auxiliary injection member recycle excess reagents in the main injection member.

[0013] Further, the auxiliary clamping member comprises an auxiliary fixed clamping seat, an auxiliary clamping sliding rod, an auxiliary movable clamping seat and an auxiliary clamping driving member, the auxiliary fixed clamping seat is fixed on the auxiliary support frame body; the auxiliary clamping sliding rod is in sliding connection with the auxiliary clamping sliding channel; the auxiliary movable clamping seat is fixedly connected with the auxiliary clamping sliding rod, and the auxiliary movable clamping seat is in sliding connection with the auxiliary fixed clamping seat; the auxiliary clamping driving member is provided with a fixed end and a telescopic end, the fixed end of the auxiliary clamping driving member is fixedly connected with an auxiliary connecting plate, and the auxiliary connecting plate is fixedly connected with the auxiliary clamping sliding rod.

[0014] Further, the auxiliary control pressure piece comprises an auxiliary moving slider and an auxiliary control pressure drive, the auxiliary moving slider is in sliding connection with the auxiliary control pressure slide, and the auxiliary moving slider is configured to: when the auxiliary moving slider is in a locking position, the auxiliary moving slider is in abutment with the auxiliary clamping slide rod, so that the auxiliary moving clamping seat stops moving; when the auxiliary moving slider is in an unlocking position, the auxiliary moving slider is disengaged from the auxiliary clamping slide rod, so that the auxiliary moving clamping seat can move relative to the auxiliary fixed clamping seat; the auxiliary control pressure drive is provided with a fixed end and a telescopic end, the fixed end of the auxiliary control pressure drive is fixedly connected with the auxiliary support frame body, and the telescopic end of the auxiliary control pressure drive is fixedly connected with the auxiliary moving slider.

[0015] Further, a guide rod is further included, both ends of the guide rod are fixed on the auxiliary support frame body, and the auxiliary clamping slide rod is in sliding connection with the guide rod.

[0016] Further, the three-way valve piece is a three-way micro electromagnetic valve.

[0017] Compared with the prior art, the technical scheme of the present application has the following beneficial technical effects:

[0018] The three-way valve piece connects the main injection piece, the auxiliary injection piece and the mass spectrometry needle piece. Before pumping the reagent, the gas in the auxiliary injection piece is exhausted, then the end of the three-way valve piece connected with the auxiliary injection piece is closed, so that the main injection piece and the mass spectrometry needle piece remain in communication; when the pumping of the reagent is completed, the end of the three-way valve piece connected with the mass spectrometry needle piece is closed, so that the main injection piece and the auxiliary injection piece remain in communication. At the same time, the auxiliary control pressure pump piece operates, so that the reagent enters the auxiliary injection piece more quickly. The problem that, in the prior art, at the moment when the pumping is completed, due to the fact that the syringe pump is still in a state of pushing the syringe, there is still a certain air pressure in the syringe, which leads to the problem that the ionization effect is poor in the final stage, and thus the detection result is affected to a certain extent, is solved. BRIEF DESCRIPTION OF DRAWINGS

[0019] Figure 1 Fig. 1 is a schematic diagram of the overall structure of a mass spectrometer reagent adding device according to an embodiment of the present application;

[0020] Figure 2 Fig. 2 is another schematic diagram of the overall structure of a mass spectrometer reagent adding device according to an embodiment of the present application;

[0021] Figure 3 Fig. 3 is a schematic diagram of the side structure of a mass spectrometer reagent adding device according to an embodiment of the present application;

[0022] Figure 4 Fig. 4 is a schematic diagram of the bottom view structure of a mass spectrometer reagent adding device according to an embodiment of the present application;

[0023] Figure 5 Fig. 5 is a schematic diagram of the top view structure of a mass spectrometer reagent adding device according to an embodiment of the present application.Figure 4 Cross-sectional structure schematic diagram at A-A.

[0024] In the drawings, the components represented by the respective reference numbers are listed as follows:

[0025] 1. main injection component;

[0026] 2. auxiliary injection component;

[0027] 3. main injection pump component; 31, main support frame body; 311, main clamping slide; 312, main pump pressure slide;

[0028] 32, main clamping component; 321, main fixed clamping seat; 322, main clamping slide rod; 323, main movable clamping seat; 324, main clamping driving component; 3241, main clamping telescopic drive; 3242, main connecting plate;

[0029] 33, main pump pressure component; 331, main pump pressure push rod; 332, main pump pressure sliding block; 333, main pump pressure screw rod; 334, main pump pressure motor;

[0030] 4. main sample introduction capillary;

[0031] 5. auxiliary pressure control pump component; 51, auxiliary support frame body; 511, auxiliary clamping slide; 512, auxiliary pressure control slide;

[0032] 52, auxiliary clamping component; 521, auxiliary fixed clamping seat; 522, auxiliary clamping slide rod; 523, auxiliary movable clamping seat; 524, auxiliary clamping driving component; 5241, auxiliary connecting plate;

[0033] 53, auxiliary pressure control component; 531, auxiliary movable sliding block; 532, auxiliary pressure control drive;

[0034] 54, guide rod;

[0035] 6. auxiliary capillary;

[0036] 7. three-way valve component;

[0037] 8. mass spectrometry needle component. DETAILED DESCRIPTION

[0038] In order to facilitate the understanding of the present application, the present application will be described more fully below with reference to the accompanying drawings. The embodiments of the present application are shown in the drawings. However, the present application can be implemented in many different forms, and is not limited to the embodiments described herein. On the contrary, the purpose of providing these embodiments is to make the disclosure of the present application more thorough and comprehensive.

[0039] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used in the description herein is for describing particular embodiments only and is not intended to be limiting of the application.

[0040] It is to be understood that the spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientations depicted in the figures. For example, if a device described herein is turned over in use or operation, a relative preposition such as "below" can be oriented upward, rather than downward, and the like. Consequently, the exemplary term "below" can include both an orientation of above and below. The device can be otherwise oriented (for example, rotated 90 degrees or at other orientations) and the spatially relative terms used herein interpreted accordingly.

[0041] It is to be understood that the spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientations depicted in the figures. For example, if a device described herein is turned over in use or operation, a relative preposition such as "below" can be oriented upward, rather than downward, and the like. Consequently, the exemplary term "below" can include both an orientation of above and below. The device can be otherwise oriented (for example, rotated 90 degrees or at other orientations) and the spatially relative terms used herein interpreted accordingly.

[0042] As used herein, the singular forms "a", "an" and "the" include plural referents unless the context clearly dictates otherwise. It is to be understood that the terms "comprising", "comprises" and "comprised of" or "comprising" or "comprise" or "comprises" or "having" or "including" or "containing" as used herein are used in the sense of "including", and the terms "a" or "an" or "the" preceding the term "comprise" or "comprises" or "comprised of" or "comprising" or "comprise" or "comprises" or "having" or "including" or "containing" are used in the sense of "including" but do not exclude the presence of

[0043] As Figures 1 to 5As shown, a mass spectrometer reagent adding device includes a main injection part 1, a secondary injection part 2, a main injection pump part 3, a main sampling capillary 4, a secondary pressure control pump part 5, a secondary capillary 6, a three-way valve part 7, and a mass spectrometer needle part 8. The main injection pump part 3 is connected with the main injection part 1. One end of the main sampling capillary 4 is connected with the main injection part 1. The secondary pressure control pump part 5 is connected with the secondary injection part 2. The secondary pressure control pump part 5 is used to open when the main injection pump part 3 completes pumping reagent, so as to recycle the excess reagent in the main injection part 1 into the secondary injection part 2. One end of the secondary capillary 6 is connected with the secondary injection part 2. The first end of the three-way valve part 7 is connected with the main sampling capillary 4. The second end of the three-way valve part 7 is connected with the secondary capillary 6. The mass spectrometer needle part 8 is connected with the third end of the three-way valve part 7.

[0044] In the embodiment, the three-way valve part 7 connects the main injection part 1, the secondary injection part 2, and the mass spectrometer needle part 8. Before pumping reagent, the gas in the secondary injection part 2 is exhausted, and then the one end of the three-way valve part 7 connected with the secondary injection part 2 is closed, so that the main injection part 1 keeps in communication with the mass spectrometer needle part 8. When the pumping of reagent is completed, the one end of the three-way valve part 7 connected with the mass spectrometer needle part 8 is closed, so that the main injection part 1 keeps in communication with the secondary injection part 2. At the same time, the secondary pressure control pump part 5 operates, so that the reagent enters the secondary injection part 2 more quickly. The problem that the ionization effect is poor in the final stage and the detection result is affected to some extent due to the fact that the injection pump is still in the state of pushing the syringe at the moment when the pumping is completed is solved.

[0045] In some embodiments, the main injection pump part 3 includes a main support frame body 31, a main clamping part 32, and a main pump pressure part 33. The main support frame body 31 is provided with a main clamping slide 311 and a main pump pressure slide 312. The main clamping part 32 is connected on the main support frame body 31. The main clamping part 32 is configured to clamp the main injection part 1 when the main clamping part 32 is in a locking position, so as to fix the main injection part 1. The main clamping part 32 is separated from the main injection part 1 when the main clamping part 32 is in an unlocking position, so as to disassemble the main injection part 1. The main pump pressure part 33 is connected on the main support frame body 31. The main pump pressure part 33 is configured to press the pressing end of the main injection part 1 when pumping reagent is needed, so as to pump the reagent in the main injection part 1. The main pump pressure part 33 stops moving when pumping reagent needs to be stopped, so as to stop the main injection part 1 from pumping reagent.

[0046] In the embodiment, the main card connector 32 is used to clamp the main injection member 1, the main pump pressing member 33 is used to press the pressing end of the main injection member 1 by the main pump pressing slide 312 when the reagent needs to be pumped out of the main injection member 1, so that the reagent in the main injection member 1 is pumped out; when the pumping of the reagent needs to be stopped, the main pump pressing member 33 stops moving, so that the main injection member 1 stops pumping the reagent.

[0047] In some embodiments, the main card connector 32 comprises a main fixed card seat 321, a main card sliding rod 322, a main movable card seat 323 and a main card driving member 324, the main fixed card seat 321 is fixed on the main support frame 31; the main card sliding rod 322 is in sliding connection with the main card sliding channel 311; the main movable card seat 323 is in fixed connection with the main card sliding rod 322, and the main movable card seat 323 is in sliding connection with the main fixed card seat 321; the main card driving member 324 is used to drive the main card sliding rod 322 to slide on the main card sliding channel 311.

[0048] In the embodiment, the main fixed card seat 321 is fixed on the main support frame 31, and the main movable card seat 323 can move close to and away from the main fixed card seat 321 under the driving of the main card driving member 324. Therefore, when the main injection member 1 needs to be fixed, the main movable card seat 323 is driven by the main card driving member 324 to move close to the main injection member 1 until the main injection member 1 is stably fixed, that is, the clamping action is completed.

[0049] In some embodiments, the main card driving member 324 comprises a main card telescopic driving member 3241, the main card telescopic driving member 3241 is provided with a fixed end and a telescopic end, the fixed end of the main card telescopic driving member 3241 is fixed on the main support frame 31, and the telescopic end of the main card telescopic driving member 3241 is connected with a main connecting plate 3242, and the main connecting plate 3242 is in fixed connection with the main card sliding rod 322.

[0050] In the embodiment, the main card driving member 324 adopts an SMC cylinder CQ2B, and the main card driving member 324 also adopts a two-phase four-wire stepping telescopic motor, which should also be within the protection scope of the application.

[0051] In some embodiments, the main pump pressing member 33 comprises a main pump pressing push rod 331, a main pump pressing sliding block 332, a main pump pressing screw rod 333 and a main pump pressing motor 334. The main pump pressing push rod 331 is in sliding connection with the main fixed clamping seat 321, and the main pump pressing push rod 331 is clamped with the telescopic end of the main injection member 1. One end of the main pump pressing sliding block 332 is in sliding connection with the main pump pressing sliding channel 312, and the other end of the main pump pressing sliding block 332 is fixedly connected with the main pump pressing push rod 331. The main pump pressing screw rod 333 is in rotational connection with the main support frame 31, and the main pump pressing sliding block 332 is in threaded connection with the main pump pressing screw rod 333. The main pump pressing motor 334 is provided with a fixed end and a rotating end. The fixed end of the main pump pressing motor 334 is fixedly connected with the main support frame 31, and the rotating end of the main pump pressing motor 334 is fixedly connected with the main pump pressing screw rod 333.

[0052] In the present embodiment, the main pump pressing sliding block 332 is in threaded connection with the main pump pressing screw rod 333. When the main pump pressing screw rod 333 rotates, the main pump pressing sliding block 332 can make reciprocating motion on the main pump pressing screw rod 333. The rotating end of the main pump pressing motor 334 is fixedly connected with the main pump pressing screw rod 333, so that the main pump pressing motor 334 can drive the main pump pressing screw rod 333 to rotate. The main pump pressing sliding block 332 is fixedly connected with the main pump pressing push rod 331, and the main pump pressing push rod 331 is clamped with the telescopic end of the main injection member 1. Thus, under the driving of the main pump pressing motor 334, the main pump pressing push rod 331 can push the telescopic end of the main injection member 1 to perform the actions of compression and pulling back.

[0053] In some embodiments, the auxiliary control pressure pump member 5 comprises an auxiliary support frame 51, an auxiliary clamping member 52 and an auxiliary control pressure member 53. The auxiliary support frame 51 is provided with an auxiliary clamping sliding channel 511 and an auxiliary control pressure sliding channel 512. The auxiliary clamping member 52 is connected to the auxiliary support frame 51. The auxiliary clamping member 52 is configured to clamp the auxiliary injection member 2 when the auxiliary clamping member 52 is in a locked position, so as to fix the auxiliary injection member 2. When the auxiliary clamping member 52 is in an unlocked position, the auxiliary clamping member 52 is separated from the auxiliary injection member 2, so as to disassemble the auxiliary injection member 2. The auxiliary control pressure member 53 is connected to the auxiliary support frame 51. The auxiliary control pressure member 53 is configured to be in a locked position before pumping reagents, so as to limit the telescopic end of the auxiliary injection member 2 in a compressed state. When the pumping of reagents is completed, the auxiliary control pressure member 53 is in an unlocked position, so that the auxiliary injection member 2 recycles the excess reagents in the main injection member 1.

[0054] In the embodiment, the sub-needle piece 2 is clamped when the sub-clamping piece 52 is in the locking position, so as to be fixed; the sub-clamping piece 52 is separated from the sub-needle piece 2 when the sub-clamping piece 52 is in the unlocking position, so as to be disassembled. Before pumping the reagent, the sub-pressure control piece 53 is in the locking position, so as to limit the telescopic end of the sub-needle piece 2 in the compressed state; when the pumping of the reagent is completed, the sub-pressure control piece 53 is in the unlocking position, so as to make the sub-needle piece 2 recycle the excess reagent in the main-needle piece 1. Thus, the problem that the ionization effect is poor in the final stage and the detection result is affected to some extent due to the existence of a certain air pressure in the syringe because the injection pump is still in the state of pushing the syringe at the moment when the pumping is completed is solved.

[0055] In some embodiments, the sub-clamping piece 52 comprises a sub-fixed clamping seat 521, a sub-clamping sliding rod 522, a sub-moving clamping seat 523 and a sub-clamping driving piece 524, the sub-fixed clamping seat 521 is fixed on the sub-support frame body 51; the sub-clamping sliding rod 522 is in sliding connection with the sub-clamping sliding channel 511; the sub-moving clamping seat 523 is in fixed connection with the sub-clamping sliding rod 522, and the sub-moving clamping seat 523 is in sliding connection with the sub-fixed clamping seat 521; the sub-clamping driving piece 524 is provided with a fixed end and a telescopic end, the fixed end of the sub-clamping driving piece 524 is fixedly connected with a sub-connection plate 5241, and the sub-connection plate 5241 is fixedly connected with the sub-clamping sliding rod 522.

[0056] In the embodiment, the sub-fixed clamping seat 521 is fixed on the sub-support frame body 51, and the sub-moving clamping seat 523 can move close to and away from the sub-fixed clamping seat 521 under the driving of the sub-clamping driving piece 524. Thus, when it is needed to fix the sub-needle piece 2, the sub-moving clamping seat 523 moves close to the sub-fixed clamping seat 521 under the driving of the sub-clamping driving piece 524 until the sub-needle piece 2 is stably fixed. In addition, the sub-clamping driving piece 524 adopts the SMC cylinder CQ2B, and the sub-clamping driving piece 524 adopts the two-phase four-wire stepping telescopic motor, which should also be within the protection scope of the application.

[0057] In some embodiments, the auxiliary pressure control part 53 comprises an auxiliary moving slider 531 and an auxiliary pressure control drive 532, the auxiliary moving slider 531 is in sliding connection with the auxiliary pressure control slide 512, and the auxiliary moving slider 531 is configured to abut against the auxiliary clamping slide rod 522 when the auxiliary moving slider 531 is in a locking position, so as to stop the auxiliary moving clamping seat 523 from moving; when the auxiliary moving slider 531 is in an unlocking position, the auxiliary moving slider 531 is disengaged from the auxiliary clamping slide rod 522, so as to enable the auxiliary moving clamping seat 523 to move relative to the auxiliary fixed clamping seat 521; the auxiliary pressure control drive 532 is provided with a fixed end and a telescopic end, the fixed end of the auxiliary pressure control drive 532 is fixedly connected with the auxiliary support frame body 51, and the telescopic end of the auxiliary pressure control drive 532 is fixedly connected with the auxiliary moving slider 531.

[0058] In the embodiment, the telescopic end of the auxiliary pressure control drive 532 is fixedly connected with the auxiliary moving slider 531, so as to lift the auxiliary moving slider 531 when the telescopic end of the auxiliary pressure control drive 532 is extended, and to pull back the auxiliary moving slider 531 when the telescopic end of the auxiliary pressure control drive 532 is retracted, so as to realize the locking and unlocking of the auxiliary moving slider 531 against the auxiliary clamping slide rod 522.

[0059] In some embodiments, a guide rod 54 is further included, the guide rod 54 is fixed at both ends on the auxiliary support frame body 51, and the auxiliary clamping slide rod 522 is in sliding connection with the guide rod 54.

[0060] In the embodiment, the guide rod 54 is in sliding connection with the auxiliary clamping slide rod 522, so as to guide the auxiliary clamping slide rod 522.

[0061] In some embodiments, the three-way valve 7 is a three-way micro electromagnetic valve.

[0062] In the embodiment, the three-way valve 7 is a three-way micro electromagnetic valve, and the model is EDEX micro shunt valve.

[0063] Compared with the prior art, the technical scheme of the application has the following beneficial technical effects:

[0064] The three-way valve connects the main injection part, the auxiliary injection part and the mass spectrum needle. Before pumping the reagent, the gas in the auxiliary injection part is exhausted, then the end of the three-way valve connected with the auxiliary injection part is closed, so that the main injection part keeps in communication with the mass spectrum needle; when the pumping of the reagent is completed, the end of the three-way valve connected with the mass spectrum needle is closed, so that the main injection part keeps in communication with the auxiliary injection part. Meanwhile, the auxiliary pressure control pump operates, so that the reagent can enter the auxiliary injection part more quickly. The problem that the ionization effect is poor in the final stage and the detection result is affected to a certain extent is solved.

[0065] The above merely describes the preferred embodiments of the present application, and is not intended to limit the present application. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. A mass spectrometer reagent adding device, characterized in that, include: Main injection part (1) and auxiliary injection part (2); A main injection pump component (3), which is connected to the main injection component (1); A main injection capillary (4), one end of which is connected to the main injection piece (1); A secondary pressure-controlled pump component (5) connected to the secondary injection component (2), the secondary pressure-controlled pump component (5) being configured to be opened when the primary injection pump component (3) has completed pumping the reagent, so as to recover excess reagent in the primary injection component (1) into the secondary injection component (2); The auxiliary pressure control pump component (5) comprises: A secondary support frame (51) is provided with a secondary clamping slideway (511) and a secondary pressure control slideway (512); A secondary clamping member (52) is connected to the secondary support frame (51), and the secondary clamping member (52) is configured to: when the secondary clamping member (52) is in a locked position, clamp the secondary injection member (2) to fix the secondary injection member (2); when the secondary clamping member (52) is in an unlocked position, the secondary clamping member (52) is separated from the secondary injection member (2) to disassemble the secondary injection member (2); A secondary pressure control member (53) is connected to the secondary support frame (51), and the secondary pressure control member (53) is configured as follows: before pumping the reagent, the secondary pressure control member (53) is in a locked position to limit the telescopic end of the secondary injection member (2) to a compressed state; when the pumping of the reagent is completed, the secondary pressure control member (53) is in an unlocked position to allow the secondary injection member (2) to recover excess reagent in the main injection member (1); A secondary capillary (6), one end of which is connected to the secondary injection piece (2); a three-way valve member (7), a first end of which is connected to the main sampling capillary (4), and a second end of which is connected to the auxiliary capillary (6); A mass spectrometer needle component (8) is connected to the third end of the three-way valve component (7).

2. A mass spectrometer reagent adding device according to claim 1, characterized in that: The main injection pump component (3) comprises: A main support frame (31) is provided with a main clamping slideway (311) and a main pumping slideway (312); A main clamping member (32) is connected to the main support frame (31), and the main clamping member (32) is configured to: when the main clamping member (32) is in a locking position, clamp the main injection member (1) to fix the main injection member (1); when the main clamping member (32) is in an unlocking position, the main clamping member (32) is separated from the main injection member (1) to disassemble the main injection member (1); A main pump pressure member (33) is connected to the main support frame (31), and the main pump pressure member (33) is configured as follows: when it is necessary to pump the reagent, the main pump pressure member (33) presses the pressing end of the main injection member (1) to pump out the reagent in the main injection member (1); when it is necessary to stop pumping the reagent, the main pump pressure member (33) stops moving to stop the main injection member (1) from pumping the reagent.

3. A mass spectrometer reagent adding device according to claim 2, characterized in that: The main clamping member (32) comprises: A main fixed card seat (321) fixed on the main support frame (31); A main clamping slide bar (322) slidably connected to the main clamping slideway (311); A main movable card seat (323) is fixedly connected to the main card slide (322), and the main movable card seat (323) is slidably connected to the main fixed card seat (321); A main clamping drive member (324) is used to drive the main clamping slide bar (322) to slide on the main clamping slideway (311).

4. A mass spectrometer reagent adding device according to claim 3, characterized in that: The main clamping drive member (324) comprises: A main clamping telescopic drive (3241) is provided with a fixed end and a telescopic end, wherein the fixed end of the main clamping telescopic drive (3241) is fixed to the main support frame (31), and the telescopic end of the main clamping telescopic drive (3241) is connected to a main connecting plate (3242), and the main connecting plate (3242) is fixedly connected to the main clamping slide rod (322).

5. A mass spectrometer reagent adding device according to claim 3, characterized in that: The main pump pressure member (33) comprises: A main pump pressure push rod (331) is slidably connected to the main fixed clamping seat (321), and the main pump pressure push rod (331) is clamped to the telescopic end of the main injection piece (1); A main pump pressure slider (332), one end of which is slidably connected to the main pump pressure slideway (312), and the other end of which is fixedly connected to the main pump pressure push rod (331); A main pump pressure screw (333) is rotatably connected to the main support frame (31), and the main pump pressure slider (332) is threadedly connected to the main pump pressure screw (333); A main pump pressure motor (334) is provided with a fixed end and a rotating end, wherein the fixed end of the main pump pressure motor (334) is fixedly connected to the main support frame (31), and the rotating end of the main pump pressure motor (334) is fixedly connected to the main pump pressure screw (333).

6. A mass spectrometer reagent adding device according to claim 1, characterized in that: The secondary clamping member (52) comprises: A secondary fixed card seat (521), which is fixed on the secondary support frame (51); A secondary clamping slide bar (522) slidably connected to the secondary clamping slideway (511); A secondary movable card-joining seat (523) is fixedly connected to the secondary card-joining slide bar (522), and the secondary movable card-joining seat (523) is slidably connected to the secondary fixed card-joining seat (521); A secondary clamping drive member (524) is provided with a fixed end and a telescopic end, the fixed end of the secondary clamping drive member (524) being fixedly connected to a secondary connecting plate (5241), and the secondary connecting plate (5241) being fixedly connected to the secondary clamping slide rod (522).

7. A mass spectrometer reagent adding device according to claim 6, characterized in that: The auxiliary pressure control member (53) comprises: A secondary movable slider (531) is slidably connected to the secondary pressure control slideway (512), and the secondary movable slider (531) is configured such that: when the secondary movable slider (531) is in a locked position, the secondary movable slider (531) abuts against the secondary clamping slide bar (522) to stop the secondary movable clamping seat (523) from moving; when the secondary movable slider (531) is in an unlocked position, the secondary movable slider (531) is disengaged from the secondary clamping slide bar (522) to enable the secondary movable clamping seat (523) to move relative to the secondary fixed clamping seat (521); The auxiliary pressure-controlled drive (532) is provided with a fixed end and a telescopic end, wherein the fixed end of the auxiliary pressure-controlled drive (532) is fixedly connected to the auxiliary support frame (51), and the telescopic end of the auxiliary pressure-controlled drive (532) is fixedly connected to the auxiliary movable slider (531).

8. A mass spectrometer reagent adding device according to claim 7, characterized in that: It also includes a guide rod (54), both ends of which are fixed on the auxiliary support frame (51), and the auxiliary clamping slide rod (522) is slidably connected to the guide rod (54).

9. A mass spectrometer reagent adding device according to claim 1, characterized in that: The three-way valve component (7) is a three-way micro solenoid valve.

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