Sample detection pen

Abstract

The utility model provides a sample detection pen, which relates to the technical field of sample detection, and comprises a base and a sampling test assembly, the base is provided with a first limiting structure and a buffer cavity for storing a buffer solution, and the sampling test assembly is provided with a second limiting structure and a sampling head located at the bottom end; the first limiting structure and the second limiting structure are configured to limit the sampling and testing assembly until the bottom end of the sampling head is immersed into a first depth of the buffer solution and allow the bottom end of the sampling head to be immersed into a second depth of the buffer solution under the action of external force, and the second depth is greater than the first depth. According to the sample detection pen provided by the utility model, even if the sampling amount of the sampling head is very small, the false negative condition can be effectively reduced.

Description

TECHNICAL FIELD

[0001] The utility model relates to sample detection technical field especially is related to a sample detection pen. BACKGROUND

[0002] At present, the existing sample detection pen is once stretched to the bottom end of the buffer solution below the sealing film after the sampling test component pierces the sealing film during operation, which makes the mixing time of the buffer solution and the sample on the sampling test component shorter, and the mixed test liquid is quickly absorbed into the test chamber after short time mixing for detection by the test element in the test chamber. When the sampling amount of the sample collection component is small, the sample amount dissolved in the buffer solution cannot meet the test demand, false negative situation occurs, and the test fails. UTILITARY MODEL

[0003] The utility model aims at providing a sample detection pen, which can effectively reduce the occurrence of false negative situation even if the sampling amount of the sampling head is small.

[0004] To achieve the above-mentioned purpose, the utility model provides the following technical scheme:

[0005] The utility model provides a sample detection pen, which comprises a base and a sampling test component, the base is provided with a first limiting structure and a buffer cavity for storing buffer solution, and the sampling test component is provided with a second limiting structure and a sampling head at the bottom end.

[0006] The first limiting structure and the second limiting structure are configured to limit the sampling test component to the bottom end of the sampling head to be immersed to the first depth of the buffer solution and allow the bottom end of the sampling head to be immersed to the second depth of the buffer solution under the action of external force, and the second depth is greater than the first depth.

[0007] Further, the sampling test component has a test chamber and a flow guide channel for guiding the liquid absorbed by the sampling head to the test chamber, and the sampling head protrudes from one end of the flow guide channel away from the test chamber.

[0008] Further, when the bottom end of the sampling head is immersed to the first depth of the buffer solution, the sampling head is completely immersed in the buffer solution, and the mixed test liquid formed by the sample on the sampling head and the buffer solution does not enter the test chamber.

[0009] Further, when the bottom end of the sampling head is immersed to the second depth of the buffer solution, the sampling head abuts against the bottom of the buffer cavity, so that the mixed test liquid formed by the sample on the sampling head and the buffer solution enters the test chamber through the flow guide channel.

[0010] Further, the first limiting structure comprises a first limiting surface, and the second limiting structure comprises a second limiting surface configured to cooperate with the first limiting surface to limit the sampling test assembly to a first depth of the sampling head immersed into the buffer solution.

[0011] The first limiting surface is recessed on the inner wall of the base, and the second limiting surface is protruded on the outer wall of the sampling test assembly.

[0012] Or the first limiting surface is protruded on the inner wall of the base, and the second limiting surface is recessed on the outer wall of the sampling test assembly.

[0013] Or the first limiting surface is protruded on the inner wall of the base, and the second limiting surface is protruded on the outer wall of the sampling test assembly.

[0014] Further, the first limiting structure comprises an inner thread provided on the inner wall of the base, and the second limiting structure comprises an outer thread provided on the outer wall of the sampling test assembly.

[0015] Further, the base comprises a liquid storage bottle, a sleeve and a sealing film, the sealing film is connected with the liquid storage bottle, a sealed buffer cavity is formed between the sealing film and the liquid storage bottle, the sleeve is connected with the liquid storage bottle and is provided with a first sealing ring between the sleeve and the liquid storage bottle, and the inner wall of the sleeve is provided with the first limiting structure.

[0016] Further, the sampling test assembly comprises a collection rod, a tube body, a cover and a second sealing ring.

[0017] One end of the collection rod is provided with the sampling head, the other end of the collection rod is inserted into one end of the tube body and forms the flow guide channel between the collection rod and the tube body, the other end of the tube body is covered with the cover and forms the test cavity between the tube body and the cover.

[0018] The outer wall of the tube body inserted with one end of the collection rod is provided with the second sealing ring and the second limiting structure.

[0019] Further, the second limiting structure is located on the side of the second sealing ring away from the sampling head.

[0020] Further, the sampling test assembly comprises a support provided in the test cavity and a test element provided on the support, and the test element is used for testing the sample.

[0021] The sample detection pen provided by the utility model has the following beneficial effects:

[0022] In use of the sample detection pen, first, the sampling test assembly is limited to the bottom end of the sampling head to the first depth of the buffer liquid under the limitation of the first limiting structure and the second limiting structure, at this time, the user can place the sampling test assembly for a period of time, and in this period of time, the user can also slightly shake the sample detection pen, so that the sample on the sampling head is fully released into the buffer liquid to form a mixed test liquid, then an external force is applied to the first limiting structure and the second limiting structure, so that the bottom end of the sampling head is immersed to the second depth of the buffer liquid, so as to detect the mixed test liquid.

[0023] Compared with the prior art, the sample detection pen can limit the sampling head to the first depth of the buffer liquid, facilitate the user to fully mix the sample with the buffer liquid, and does not affect the further immersion of the sampling head into the buffer liquid, realizes the detection of the mixed test liquid, and even if the sampling amount of the sampling head is small, the occurrence of false negative situation can be effectively reduced. BRIEF DESCRIPTION OF DRAWINGS

[0024] In order to more clearly illustrate the specific embodiments of the present application or the technical solutions in the prior art, the drawings needed in the specific embodiments or the prior art description will be briefly introduced as follows. Obviously, the drawings in the following description are some embodiments of the present application, and for those skilled in the art, other drawings can also be obtained without creative labor on the basis of these drawings.

[0025] Figure 1 A three-dimensional structural schematic view of the sample detection pen is provided.

[0026] Figure 2 A sectional view of the sleeve is provided.

[0027] Figure 3 A three-dimensional structural schematic view of the tube body is provided.

[0028] Figure 4 An exploded view of the sample detection pen is provided.

[0029] Figure 5 A sectional view of the sample detection pen in the first state is provided.

[0030] Figure 6 A sectional view of the sample detection pen in the second state is provided.

[0031] Icon: 1 - base; 11 - first limiting structure; 111 - first limiting surface; 112 - internal thread; 12 - buffer cavity; 13 - liquid storage bottle; 14 - sleeve; 15 - sealing film; 16 - first sealing ring; 2 - sampling test assembly; 21 - second limiting structure; 211 - second limiting surface; 212 - external thread; 22 - test cavity; 23 - flow guide channel; 24 - collection rod; 241 - sampling head; 242 - connecting structure; 25 - tube body; 26 - cover; 27 - second sealing ring; 28 - bracket; 29 - test element. DETAILED DESCRIPTION

[0032] The technical solutions of the present application will be described in detail below with reference to the drawings. Obviously, the described embodiments are only some of the embodiments of the present application, not all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0033] In the description of the present application, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer" and the like indicate the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as limiting the present application. In addition, the terms "first", "second", "third" are only for descriptive purposes and cannot be understood as indicating or implying relative importance.

[0034] In the description of the present application, it should be noted that unless otherwise explicitly specified and limited, the terms "mounting", "connection", "connection" should be understood broadly, for example, it can be fixedly connected, or it can be detachably connected, or integrally connected; it can be mechanically connected, or it can be electrically connected; it can be directly connected, or it can be indirectly connected through an intermediate medium; it can be the communication inside two elements. For those skilled in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances.

[0035] The specific embodiments of the present application will be described in detail below with reference to the drawings. It should be understood that the specific embodiments described here are only used to illustrate and explain the present application, and are not used to limit the present application.

[0036] The present embodiment is to provide a sample detection pen, such as Figures 1 to 6As shown, the sample detection pen includes a base 1 and a sampling test assembly 2, the base 1 is provided with a first limiting structure 11 and a buffer cavity 12 for storing buffer solution, and the sampling test assembly 2 is provided with a second limiting structure 21 and a sampling head 241 at the bottom end; the first limiting structure 11 and the second limiting structure 21 are configured to limit the sampling test assembly 2 to the bottom end of the sampling head 241 to be immersed in the buffer solution to a first depth, and allow the bottom end of the sampling head 241 to be immersed in the buffer solution to a second depth under the action of an external force, the second depth is greater than the first depth.

[0037] As shown in Figure 5 and Figure 6 The use process of the above-mentioned sample detection pen will be described in detail:

[0038] As shown in Figure 5 , first, the sampling test assembly 2 is aligned with the base 1 below in the vertical direction, and then the sampling test assembly 2 is lowered until the first limiting structure 11 and the second limiting structure 21 abut, and the sampling test assembly 2 is limited to the bottom end of the sampling head 241 to be immersed in the buffer solution to a first depth under the limitation of the first limiting structure 11 and the second limiting structure 21, at this time the user can place the sampling test assembly 2 for a period of time, and during this period of time, the user can also slightly shake the sample detection pen, so that the sample on the sampling head 241 is fully released into the buffer solution to form a mixed test liquid; then an external force is applied to the first limiting structure 11 and the second limiting structure 21, as shown in Figure 6 , so that the bottom end of the sampling head 241 is immersed in the buffer solution to a second depth, thereby detecting the mixed test liquid.

[0039] In the sample detection pen provided by the above-mentioned embodiment, the base 1 is provided with the first limiting structure 11, and the sampling test assembly 2 is provided with the second limiting structure 21, during the process of lowering the sampling test assembly 2, the bottom end of the sampling head 241 can be limited to the first depth of the buffer solution under the limitation of the first limiting structure 11 and the second limiting structure 21, the user can stop lowering the sampling test assembly 2, and then continue to lower the sampling test assembly 2 after waiting for a period of time, so that the sample on the sampling head 241 can be more fully mixed with the buffer solution.

[0040] Therefore, the sample detection pen provided by the above-mentioned embodiment divides the original one-step insertion of the sampling test assembly 2 into two steps, prolongs the contact time of the sample and the buffer solution, increases the sample concentration in the mixed test liquid, and improves the detection accuracy.

[0041] It should be noted that the sampling head 241 can be used for sampling of solid, semi-solid and liquid samples, and different sampling heads can be selected for different forms of samples.

[0042] It should be noted that the external force can be transmitted to the first limiting structure 11 and the second limiting structure 21 through the sampling and testing assembly 2 and / or the base 1, or directly act on the first limiting structure 11 and the second limiting structure 21.

[0043] In the following embodiments, the external force is transmitted to the first limiting structure 11 and the second limiting structure 21 through the sampling and testing assembly 2 and / or the base 1. This arrangement is more convenient for the user to operate, and the first limiting structure 11 and the second limiting structure 21 do not need to be externally arranged for the user to hold, and the first limiting structure 11 and the second limiting structure 21 do not need to be designed to have a larger size for the user to operate.

[0044] In an optional embodiment, as shown in Figure 5 The sampling and testing assembly 2 has a testing cavity 22 and a flow guide channel 23 for guiding the liquid absorbed by the sampling head 241 to the testing cavity 22, and the sampling head 241 is arranged at the end of the flow guide channel 23 away from the testing cavity 22.

[0045] In the above embodiment, the sampling head 241 is arranged at the end of the flow guide channel 23 away from the testing cavity 22, which facilitates the sampling head 241 to preferentially extend into the buffer solution in the base 1. In operation, the sampling head 241 preferentially extends into the buffer solution, and the sample thereon is fully mixed with the buffer solution, and then the mixed sample solution enters the testing cavity 22 through the flow guide channel 23 for testing.

[0046] In an optional embodiment, when the bottom end of the sampling head 241 is immersed to a first depth in the buffer solution, the sampling head 241 is fully immersed in the buffer solution, so that the sample on the sampling head 241 can be fully mixed with the buffer solution to form a mixed sample solution.

[0047] In the above process, optionally, the mixed sample solution does not enter the testing cavity 22. That is, during the standing mixing process, the first depth to which the bottom end of the sampling head 241 is immersed is not sufficient for the mixed sample solution to enter the testing cavity 22, so as to ensure that the sample is not tested even at the end of the mixing.

[0048] In an optional embodiment, as shown in Figure 6 When the bottom end of the sampling head 241 is immersed to a second depth in the buffer solution, the sampling head 241 abuts against the bottom of the buffer cavity 12, and the sampling head 241 is lowered to the deepest position that it can be lowered to, so that the sample on the sampling head 241 and the buffer solution form a mixed sample solution which enters the testing cavity 22 through the flow guide channel 23, and the testing of the sample is realized.

[0049] In the above embodiment, under the action of the external force, the first limiting structure 11 and the second limiting structure 21 allow the bottom end of the sampling head 241 to be immersed into the bottom of the buffer cavity 12, so that the first limiting structure 11 and the second limiting structure 21 do not limit the deepest position of the sampling head 241, on the one hand, reducing the waste of the buffer solution, and on the other hand, facilitating the mixed test liquid to enter the test cavity 22 through the flow guide channel 23.

[0050] The first limiting structure 11 and the second limiting structure 21 can adopt various limiting forms. In an optional embodiment, the first limiting structure 11 includes a first limiting surface 111, and the second limiting structure 21 includes a second limiting surface 211, which is used to cooperate with the first limiting surface 111 to limit the sampling test assembly 2 to the first depth of the bottom end of the sampling head 241 immersed into the buffer solution.

[0051] The first limiting surface 111 and the second limiting surface 211 are arranged to hinder the sampling test assembly 2 from continuing to be lowered, that is, to give a certain resistance to the user during the process of the user holding the sampling test assembly 2 to be lowered, so that the user feels that the sampling test assembly 2 is preliminarily lowered in place, and can stop the sampling test assembly 2 from being lowered, and stand still for a period of time or be slightly shaken to promote the mixing of the sample and the buffer solution.

[0052] The first limiting surface 111 and the second limiting surface 211 can have various cooperation modes, for example, clamping or abutting.

[0053] When the first limiting surface 111 and the second limiting surface 211 are clamped, the first limiting surface 111 is recessed on the inner wall of the base 1, and the second limiting surface 211 is protruded on the outer wall of the sampling test assembly 2; or the first limiting surface 111 is protruded on the inner wall of the base 1, and the second limiting surface 211 is recessed on the outer wall of the sampling test assembly 2.

[0054] In the above embodiment, when the sampling test assembly 2 is lowered to the clamped first limiting surface 111 and the second limiting surface 211, the user can stop lowering the sampling test assembly 2, and after a period of time, the user presses the sampling test assembly 2 to force the second limiting surface 211 to cancel the clamping with the first limiting surface 111, so that the sampling test assembly 2 can continue to move downward.

[0055] Taking the example that the first limiting surface 111 is recessed on the inner wall of the base 1, and the second limiting surface 211 is protruded on the outer wall of the sampling test assembly 2:

[0056] The first limiting surface 111 can form a groove recessed in the inner wall of the base 1, and the groove can have a shape such as a semispherical shape, a conical shape, a rectangular shape, or a ring shape. The second limiting surface 211 can form a protrusion protruding from the outer wall of the sampling and testing assembly 2, and the protrusion can have a shape matching the shape of the groove.

[0057] In an optional embodiment, the protrusion can be made of an elastic material such as rubber or silica gel, so that the user can cancel the clamping of the second limiting surface 211 and the first limiting surface 111 by applying force.

[0058] When the first limiting surface 111 and the second limiting surface 211 abut against each other, the first limiting surface 111 protrudes from the inner wall of the base 1, and the second limiting surface 211 protrudes from the outer wall of the sampling and testing assembly 2. It can be understood that, since the first limiting surface 111 and the second limiting surface 211 both protrude, the first limiting surface 111 will abut against the second limiting surface 211 during the process of the sampling and testing assembly 2 entering the base 1, thereby limiting the continuous lowering of the sampling and testing assembly 2.

[0059] The first limiting surface 111 can be regarded as the top surface of a first protrusion protruding from the inner wall of the base 1, and the second limiting surface 211 can be regarded as the bottom surface of a second protrusion protruding from the outer wall of the sampling and testing assembly 2. One of the first protrusion and the second protrusion can have a ring shape, and the other can have a ring shape or a semispherical shape, a conical shape, or a rectangular shape.

[0060] In an optional embodiment, the first protrusion and the second protrusion can be made of an elastic material such as rubber or silica gel, so that the user can cancel the clamping of the second limiting surface 211 and the first limiting surface 111 by applying force.

[0061] In an optional embodiment, as an example, Figure 5 the first limiting structure 11 includes an internal thread 112 arranged on the inner wall of the base 1, and the second limiting structure 21 includes an external thread 212 arranged on the outer wall of the sampling and testing assembly 2.

[0062] As shown in Figure 2 , the top end of the internal thread 112 can have a first limiting surface 111, and as shown in Figure 3 , the bottom end of the external thread 212 can have a second limiting surface 211. When the sampling and testing assembly 2 is lowered, the second limiting surface 211 at the bottom end of the external thread 212 first contacts the first limiting surface 111 at the top end of the internal thread 112, thereby hindering the continuous lowering of the sampling and testing assembly 2. After a period of time, the sampling and testing assembly 2 can be rotated, so that the external thread 212 rotates relative to the internal thread 112, thereby achieving the rotational lowering of the sampling and testing assembly 2.

[0063] The above embodiment facilitates the machining of the first limiting structure 11 and the second limiting structure 21, and also does not require the user to apply a large external force.

[0064] In an optional embodiment, if Figure 5 As shown, the base 1 includes a liquid storage bottle 13, a sleeve 14 and a sealing membrane 15. The sealing membrane 15 is connected to the liquid storage bottle 13. A sealed buffer cavity 12 is formed between the sealing membrane 15 and the liquid storage bottle 13. The sleeve 14 is connected to the liquid storage bottle 13 and a first sealing ring 16 is provided between the sleeve 14 and the liquid storage bottle 13. The inner wall of the sleeve 14 is provided with a first limiting structure 11.

[0065] The setting of the sealing film 15 can prevent the buffer solution from leaking out when it is not in use. During the lowering of the sampling test assembly 2, the sampling head 241 can pierce the sealing film 15 and enter the buffer chamber 12. When the bottom end of the sampling head 241 is immersed in the second depth of the buffer solution, the mixed test liquid can enter the diversion channel 23 through the space enclosed by the sleeve 14, and then enter the test chamber 22 from the diversion channel.

[0066] In the above embodiment, a first sealing ring 16 is provided between the sleeve 14 and the liquid storage bottle 13 , and the first sealing ring 16 can prevent the buffer solution from leaking from between the liquid storage bottle 13 and the sleeve 14 .

[0067] In an optional embodiment, the sleeve 14 and the liquid storage bottle 13 may be threadedly connected.

[0068] In an optional embodiment, if Figure 5 As shown, the sampling test assembly 2 includes a collecting rod 24, a tube body 25, a cover 26 and a second sealing ring 27. One end of the collecting rod 24 has a sampling head 241, and the other end is inserted into one end of the tube body 25 to form a guide channel 23 between the tube body 25. The other end of the tube body 25 is covered with a cover 26 to form a test cavity 22 between the cover 26; the outer wall of the tube body 25 at one end of which the collecting rod 24 is inserted is provided with a second sealing ring 27 and a second limiting structure 21.

[0069] In the above-mentioned sampling and testing assembly 2 , the second limiting structure 21 is directly disposed on the outer wall of the tube body 25 , and the user can apply external force to the second limiting structure 21 through the tube body 25 , which facilitates the user's force application.

[0070] When using the sampling and testing assembly 2, the user first lowers the sampling and testing assembly 2. The sampling head 241 pierces the sealing membrane 15 and enters the buffer chamber 12 until the second limiting structure 21 engages with the first limiting structure 11 and the sampling head 241 is completely immersed in the buffer solution. The user then stops lowering the sampling and testing assembly 2. Later in this process, the second sealing ring 27 is able to abut against the inner wall of the base 1. Under the action of the second sealing ring 27, as the sampling and testing assembly 2 moves downward, the pressure in the cavity between the base 1 and the sampling and testing assembly 2 increases, forcing the buffer solution onto the sampling head 241 and mixing with the sample on the sampling head 241.

[0071] After a period of time, the sampling test assembly 2 is rotated, and the external thread 212 on the sampling test assembly 2 continues to travel along the internal thread 112 on the inner wall of the base 1 until the sampling head 241 abuts the bottom of the buffer cavity 12. During the above process, because the cavity pressure between the base 1 and the sampling test assembly 2 is greater than the pressure in the test cavity 22 (equivalent to atmospheric pressure), the mixed liquid to be tested flows into the test cavity 22 along the flow channel 23.

[0072] In an optional embodiment, as shown in Figure 5 The end of the collection rod 24 away from the sampling head 241 can be provided with a connecting structure 242, which is preferably a certain elastic barb, so as to facilitate insertion of the above-mentioned end of the collection rod 24 into the tube 25.

[0073] Specifically, the inner wall of the tube can be provided with a limiting step surface for limiting the barb from coming out.

[0074] In an optional embodiment, the second limiting structure 21 is located on the side of the second sealing ring 27 away from the sampling head 241, so that when the first limiting structure 11 and the second limiting structure 21 abut, the sampling head 241 can fully extend into the buffer solution.

[0075] In an optional embodiment, the tube 25 can be made of transparent material, such as plastic, glass, etc.

[0076] Of course, in other embodiments, the tube can also be partially made of transparent material, for example, the tube 25 is provided with an observation window made of transparent material, so as to facilitate the user to observe the test results in the tube 25.

[0077] In an optional embodiment, as shown in Figure 4 and Figure 5 The sampling test assembly 2 includes a bracket 28 arranged in the test cavity 22 and a test element 29 arranged on the bracket 28, and the test element 29 is used for testing the sample.

[0078] In the above embodiment, the bracket 28 can support the test element 29 and ensure the stability of the test element 29 in the test cavity 22.

[0079] In an optional embodiment, in order to facilitate installation of the bracket 28, the bracket 28 can be inserted on the cover 26.

[0080] Finally, it should be noted that: the above embodiments are used to illustrate the technical solutions of the present application, but not limited to them; although the present application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that: it can still modify the technical solutions recorded in the foregoing embodiments, or make equivalent replacement to part or all of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present application.

Claims

1. A sample detection pen, characterized by, The application relates to a sampling and testing device, which comprises a base (1) and a sampling and testing assembly (2), wherein the base (1) is provided with a first limiting structure (11) and a buffer cavity (12) for storing buffer solution, and the sampling and testing assembly (2) is provided with a second limiting structure (21) and a sampling head (241) located at the bottom end. The first limiting structure (11) and the second limiting structure (21) are configured to limit the sampling and testing assembly (2) to the state that the bottom end of the sampling head (241) is immersed in the buffer solution to a first depth, and allow the bottom end of the sampling head (241) to be immersed in the buffer solution to a second depth under the action of an external force, wherein the second depth is greater than the first depth.

2. The sample detection pen of claim 1, wherein The sampling and testing assembly (2) has a testing cavity (22) and a flow guide channel (23) for guiding the liquid absorbed by the sampling head (241) to the testing cavity (22), and the sampling head (241) is arranged at the end of the flow guide channel (23) away from the testing cavity (22).

3. The sample detection pen of claim 2, wherein, When the bottom end of the sampling head (241) is immersed in the buffer solution to the first depth, the sampling head (241) is completely immersed in the buffer solution, and the mixed sample solution formed by the sample on the sampling head (241) and the buffer solution does not enter the testing cavity (22).

4. The sample detection pen of claim 2, wherein, When the bottom end of the sampling head (241) is immersed in the buffer solution to the second depth, the sampling head (241) abuts against the bottom of the buffer cavity (12), so that the mixed sample solution formed by the sample on the sampling head (241) and the buffer solution enters the testing cavity (22) through the flow guide channel (23).

5. The sample detection pen of claim 1, wherein, The first limiting structure (11) comprises a first limiting surface (111), and the second limiting structure (21) comprises a second limiting surface (211) configured to cooperate with the first limiting surface (111) to limit the sampling and testing assembly (2) to the state that the bottom end of the sampling head (241) is immersed in the buffer solution to the first depth. The first limiting surface (111) is concavely arranged on the inner wall of the base (1), and the second limiting surface (211) is convexly arranged on the outer wall of the sampling and testing assembly (2). Alternatively, the first limiting surface (111) is convexly arranged on the inner wall of the base (1), and the second limiting surface (211) is concavely arranged on the outer wall of the sampling and testing assembly (2). Alternatively, the first limiting surface (111) is convexly arranged on the inner wall of the base (1), and the second limiting surface (211) is convexly arranged on the outer wall of the sampling and testing assembly (2).

6. The sample detection pen of claim 1, wherein, The first limiting structure (11) comprises an inner thread (112) arranged on the inner wall of the base (1), and the second limiting structure (21) comprises an outer thread (212) arranged on the outer wall of the sampling and testing assembly (2).

7. The sample detection pen of claim 1, wherein The base (1) comprises a liquid storage bottle (13), a sleeve (14) and a sealing film (15), the sealing film (15) is connected with the liquid storage bottle (13), a sealed buffer cavity (12) is formed between the sealing film (15) and the liquid storage bottle (13), the sleeve (14) is connected with the liquid storage bottle (13) and is provided with a first sealing ring (16) between the sleeve (14) and the liquid storage bottle (13), and an inner wall of the sleeve (14) is provided with the first limiting structure (11).

8. The sample detection pen of claim 2, wherein, The sampling test assembly (2) comprises a collecting rod (24), a tube body (25), a cover (26) and a second sealing ring (27). One end of the collecting rod (24) is provided with the sampling head (241), the other end of the collecting rod (24) is inserted into one end of the tube body (25) and forms the flow guide channel (23) between the collecting rod (24) and the tube body (25), the other end of the tube body (25) is provided with the cover (26) and forms the test cavity (22) between the tube body (25) and the cover (26). An outer wall of the tube body (25) into which the collecting rod (24) is inserted is provided with the second sealing ring (27) and the second limiting structure (21).

9. The sample detection pen of claim 8, wherein, The second limiting structure (21) is located on a side of the second sealing ring (27) away from the sampling head (241).

10. The sample detection pen of claim 2, wherein, The sampling test assembly (2) comprises a support (28) arranged in the test cavity (22) and a test element (29) arranged on the support (28), and the test element (29) is used for testing the sample.

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