Powder injection sterile subpackaging disc type spot check weighing continuous subpackaging machine

Abstract

The utility model discloses a disc type sampling inspection weighing continuous racking machine for powder injection sterile racking, and relates to the technical field of medicine production machinery. A bottle feeding wheel mechanism is installed at the tail end of the bottle feeding track, a bottle feeding weighing device and a powder distributing device are arranged on the inner side and the outer side of the first bottle conveying wheel respectively, the powder distributing device is connected with a powder feeding device, and a powder-filled weighing device is arranged on the inner side of the second bottle conveying wheel. Continuous bottle feeding, powder distributing, powder filling, plug buckling and conveying of powder injection are achieved, weighing and sampling inspection can be achieved, when sampling inspection is unqualified, powder injection can be directly removed, the product quality is improved, the speed is high, when sampling inspection is needed, empty penicillin bottles are weighed through the bottle feeding and weighing device, and after powder filling, the powder injection efficiency is improved. The post-powder-filling weighing device is used for weighing after powder filling, whether the powder filling amount is qualified or not can be directly known, the sampling inspection efficiency can be improved, unqualified powder filling bottles are removed through the removing and conveying device, and the quality after powder filling can be improved.

Description

Technical Field

[0001] This utility model belongs to the field of pharmaceutical production machinery technology, specifically relating to a continuous dispensing machine for sterile powder injection with tray-type sampling and weighing. Background Technology

[0002] Powder injections are injectable solutions made by filling sterile powder for injection into ampoules or by freeze-drying, and then dissolving or suspending it in a solvent before injection. Depending on the manufacturing process, powder injections can be further divided into freeze-dried products for injection and sterile repackaged products for injection. Currently, powder injections are manufactured using production lines for filling, but manual sampling is required after filling. This sampling is time-consuming, requires a cleanroom environment, is slow, and does not provide immediate results. Utility Model Content

[0003] To address the problems mentioned in the background section, the purpose of this invention is to provide a continuous, aseptic dispensing, tray-type sampling and weighing dispensing machine for powder injections.

[0004] This utility model discloses a continuous, tray-type sampling and weighing dispensing machine for aseptic powder injections, comprising an inlet wheel mechanism, a first bottle conveyor wheel, a powder dispensing device, a second bottle conveyor wheel, an inlet weighing device, a post-filling weighing device, a powder application device, an inlet track, an outlet track, a horizontal stoppering device, a rejection and conveying device, a stopper vibrating feeding device, a stopper replenishment device, and a frame. Several inlet tracks are mounted on the frame, with an inlet wheel mechanism at the end of each track. A first bottle conveyor wheel is located on one side of the inlet wheel mechanism, and a second bottle conveyor wheel is located on one side of the first bottle conveyor wheel. The inner surface of the first bottle conveyor wheel... The outer side is equipped with a bottle inlet weighing device and a powder distribution device. The powder distribution device is connected to the powder feeding device. Bottle conveyor wheel one is connected to the bottle inlet wheel mechanism and the bottle inlet weighing device. The inner side of bottle conveyor wheel two is equipped with a powder filling weighing device. The powder distribution device is connected to bottle conveyor wheel one and bottle conveyor wheel two. Bottle conveyor wheel two is connected to a horizontal stopper device located on its right side. On one side of the horizontal stopper device, there is a rejection and conveying device and a stopper vibrating feeder. The stopper replenishment device is connected to the stopper vibrating feeder. The rejection and conveying device is connected to one end of the bottle outlet track.

[0005] Preferably, the bottle infeeding wheel of the bottle infeeding mechanism is provided with 6-8 workstation slots.

[0006] Preferably, the bottle-feeding weighing device and the powder-filling post-weighing device are equipped with 3-6 workstation slots.

[0007] Preferably, the rejection and conveying device is equipped with an electric rejection rod.

[0008] Preferably, intermediate transmission wheel one, intermediate transmission wheel two, intermediate transmission wheel three, and intermediate transmission wheel four are sequentially arranged between the bottle conveying wheel two and the horizontal plugging device.

[0009] Preferably, the rotation direction of the first intermediate conveyor wheel is opposite to that of the second intermediate conveyor wheel, the second intermediate conveyor wheel, and the fourth intermediate conveyor wheel.

[0010] Preferably, the plugging device is a storage bin, and the bottom of the storage bin is connected to a discharge pipe.

[0011] Preferably, the powder feeding device is equipped with a sterile powder feeding screw dispensing head.

[0012] Compared with existing technologies, the beneficial effects of this utility model are as follows: Through the bottle inlet wheel mechanism, bottle conveyor wheel one, powder separating device, bottle conveyor wheel two, bottle inlet weighing device, post-powder filling weighing device, powder feeding device, bottle inlet track, bottle outlet track, horizontal stoppering device, rejection and conveying device, rubber stopper vibrating feeding device, stopper replenishing device, and frame, continuous bottle feeding, powder separating, powder filling, stoppering, and conveying of powder injections are achieved. Simultaneously, it enables weighing and sampling inspection; when a sample fails inspection, it can be directly rejected, improving product quality and increasing speed. Specific advantages include:

[0013] 1. When random inspection is required, the empty vials are weighed using the inlet weighing device, and after powder filling, the powder filling weighing device is used to weigh the vials. This allows for direct determination of whether the powder filling quantity is up to standard, thereby improving the efficiency of random inspection.

[0014] Second, by using a rejection and conveying device to remove unqualified powder bottles, the quality of the powder after filling can be improved, and the quality can be determined immediately. Attached Figure Description

[0015] For ease of explanation, the present invention will be described in detail below with reference to specific embodiments and accompanying drawings.

[0016] Figure 1 This is a schematic diagram of the structure of this utility model.

[0017] In the diagram: 1-Bottle inlet wheel mechanism; 2-Bottle conveyor wheel one; 3-Powder separation device; 4-Bottle conveyor wheel two; 5-Bottle inlet weighing device; 6-Powder filling and weighing device; 7-Powder feeding device; 8-Bottle inlet track; 9-Bottle outlet track; 10-Horizontal stopper device; 11-Removal and conveying device; 12-Rubber stopper vibrating feeder device; 13-Stopper replenishment device; 14-Frame; 15-Intermediate guide wheel one; 16-Intermediate guide wheel two; 17-Intermediate guide wheel three; 18-Intermediate guide wheel four. Detailed Implementation

[0018] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model is described below with reference to specific embodiments shown in the accompanying drawings. However, it should be understood that these descriptions are merely exemplary and not intended to limit the scope of this utility model. The structures, proportions, sizes, etc., illustrated in the accompanying drawings are only for illustrative purposes to aid those skilled in the art and are not intended to limit the implementation conditions of this utility model. Therefore, they have no substantial technical significance. Any modifications to the structure, changes in proportions, or adjustments to size, without affecting the effects and objectives achieved by this utility model, should still fall within the scope of the technical content disclosed in this utility model. Furthermore, descriptions of well-known structures and technologies are omitted in the following description to avoid unnecessarily obscuring the concept of this utility model.

[0019] It should also be noted that, in order to avoid obscuring the present invention with unnecessary details, only the structures and / or processing steps closely related to the solution according to the present invention are shown in the accompanying drawings, while other details that are not closely related to the present invention are omitted.

[0020] like Figure 1As shown, this specific embodiment can achieve rapid bottle feeding, powder filling, and powder injection sampling inspection. It is fast and specifically adopts the following technical solution: It includes a bottle feeding wheel mechanism 1, a bottle conveyor wheel one 2, a powder separating device 3, a bottle conveyor wheel two 4, a bottle feeding weighing device 5, a post-powder filling weighing device 6, a powder feeding device 7, a bottle feeding track 8, a bottle exit track 9, a horizontal stoppering device 10, a rejection and conveying device 11, a stopper vibrating feeding device 12, a stopper replenishing device 13, and a frame 14. Several bottle feeding tracks 8 are installed on the frame 14, enabling rapid feeding of vials. After entering the vials, the vials are fed by the bottle feeding wheel mechanism... Structure 1 facilitates bottle transport. A bottle infeed mechanism 1 is installed at the end of the bottle infeed track 8. The bottle infeed wheel of the mechanism 1 has 6-8 workstation slots. A bottle conveyor wheel 1 2 is located on one side of the mechanism 1, and a bottle conveyor wheel 2 4 is located on the other side. A bottle weighing device 5 and a powder dispensing device 3 are respectively installed on the inner and outer sides of the bottle conveyor wheel 1 2. The powder dispensing device 3 is connected to a powder feeding device 7. A sterile powder feeding screw dispensing head is installed on the powder feeding device 7. Empty vials are transported through the bottle infeed mechanism 1 and the bottle conveyor wheel 2 2 into the powder dispensing device 3, where sterile powder is fed. The screw dispensing head dispenses sterile powder quantitatively into vials via the powder tray on the powder dispensing device 3. Bottle conveyor roller 1 (2) cooperates with the bottle inlet roller mechanism 1 and the bottle inlet weighing device 5. A post-filling weighing device 6 is installed on the inner side of bottle conveyor roller 2 (4). Both the bottle inlet weighing device 5 and the post-filling weighing device 6 have 3-6 workstation slots. The bottle inlet weighing device 5 is used to weigh vials before powder filling, and the post-filling weighing device 6 is used to weigh vials after powder filling. The powder dispensing device 3 cooperates with both bottle conveyor roller 1 (2) and bottle conveyor roller 2 (4). Bottle conveyor roller 2 (4) cooperates with the horizontal stopper device 10 located on its right side. The rubber stopper of the horizontal stopper device 10 operates horizontally. On one side of the horizontal stopper device 10, there is a rejection and conveying device 11 and a rubber stopper vibrating feeder 12. The rejection and conveying device 11 is equipped with an electric rejection rod, which can reject unqualified bottles. The refill device 13 is connected to the rubber stopper vibrating feeder 12. The rubber stopper vibrating feeder 12 is a device that uses a vibrator to supply material to the stopper device. The rejection and conveying device 11 is connected to one end of the bottle discharge track 9. The refill device 13 is a storage bin. The bottom of the storage bin is connected to a discharge pipe, which can realize rapid discharge of the stopper.

[0021] Furthermore, in this specific embodiment, for installation requirements and layout, intermediate transmission wheels 15, 16, 17, and 18 are sequentially arranged between the second bottle conveyor wheel 4 and the horizontal plug device 10, respectively. The rotation direction of the first intermediate transmission wheel 15 is opposite to that of the second bottle conveyor wheel 4, the second intermediate transmission wheel 16, and the fourth intermediate transmission wheel 18.

[0022] The working principle of this specific implementation method is as follows: This machine is a disc-type continuous operation sampling and filling screw dispensing machine. During normal operation, the bottle inlet wheel mechanism 1, bottle conveyor wheel one 2, powder separation device 3, bottle conveyor wheel two 4, horizontal stopper device 10, and rejection and conveying device 11 operate continuously without weighing. When weighing is required, the bottle inlet weighing device 5 is started, running three stations to remove three vials from bottle conveyor wheel one 2. At this time, the main machine operates normally, and the bottle inlet weighing device 5 operates intermittently three times to weigh the three empty bottles and record the weights in the computer. Then, the bottle inlet wheel mechanism 1 stops running three stations, and the bottle inlet weighing device 5 stops operating. After weighing, the three bottles are sent to the first conveyor wheel 2 and the powder dispensing device 3 for powder filling, and then to the second conveyor wheel 4. At this time, the powder filling weighing device 6 operates to take out the three powder-filled bottles for weighing. (During normal operation, the bottle inlet weighing device 5 and the powder filling weighing device 6 do not rotate.) After weighing and comparing, the filling amount is determined and recorded, and then proceeds to the next stoppering process. Bottles with qualified filling amount enter the bottle outlet track, while those with unqualified filling amount are rejected by the rejection and conveying device 11. The machine speed is 500 bottles / min. At the start of operation, the full filling amount is checked at 250 bottles / min. During operation, sampling inspection is performed. The machine can be set to automatic or manual mode to ensure that the filling amount is within the qualified range.

[0023] It will be apparent to those skilled in the art that this invention is not limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or essential characteristics of this invention. Therefore, the embodiments should be considered exemplary and non-limiting in all respects, and the scope of this invention is defined by the appended claims rather than the foregoing description. Thus, it is intended that all variations falling within the meaning and scope of equivalents of the claims be included within this invention.

[0024] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A continuous, aseptic dispensing, tray-type sampling and weighing dispensing machine for powder injections, characterized in that: The system includes a bottle inlet wheel mechanism (1), a bottle conveyor wheel one (2), a powder separation device (3), a bottle conveyor wheel two (4), a bottle inlet weighing device (5), a powder filling and weighing device (6), a powder application device (7), a bottle inlet track (8), a bottle outlet track (9), a horizontal stopper device (10), a rejection and conveying device (11), a rubber stopper vibrating feeder (12), a stopper replenishment device (13), and a frame (14). Several bottle inlet tracks (8) are installed on the frame (14). A bottle inlet wheel mechanism (1) is installed at the end of the bottle inlet track (8). A bottle conveyor wheel one (2) is set on one side of the bottle inlet wheel mechanism (1), and a bottle conveyor wheel two (4) is set on one side of the bottle conveyor wheel one (2). Bottle inlet weighing devices are set on the inner and outer sides of the bottle conveyor wheel one (2). Measuring device (5), powder separating device (3), powder separating device (3) is connected to powder feeding device (7), bottle conveying wheel one (2) is respectively connected to bottle inlet wheel mechanism (1) and bottle inlet weighing device (5), bottle conveying wheel two (4) is provided with a powder filling weighing device (6) on the inner side, powder separating device (3) is respectively connected to bottle conveying wheel one (2) and bottle conveying wheel two (4), bottle conveying wheel two (4) is connected to a horizontal stopper device (10) on its right side, a rejection and conveying device (11) and a rubber stopper vibration feeding device (12) are respectively provided on one side of the horizontal stopper device (10), a stopper replenishing device (13) is connected to the rubber stopper vibration feeding device (12), and the rejection and conveying device (11) is connected to one end of the bottle exit track (9).

2. The aseptic dispensing tray-type sampling and weighing continuous dispensing machine for powder injections according to claim 1, characterized in that: The bottle inlet wheel mechanism (1) has 6-8 work station slots on its bottle inlet wheel.

3. The aseptic dispensing tray-type sampling and weighing continuous dispensing machine for powder injections according to claim 1, characterized in that: The bottle-feeding weighing device (5) and the powder-filling weighing device (6) are equipped with 3-6 workstation slots.

4. The aseptic dispensing tray-type sampling and weighing continuous dispensing machine for powder injections according to claim 1, characterized in that: An electric rejection rod is installed on the rejection and conveying device (11).

5. The aseptic dispensing tray-type sampling and weighing continuous dispensing machine for powder injections according to claim 1, characterized in that: Intermediate transmission wheel one (15), intermediate transmission wheel two (16), intermediate transmission wheel three (17), and intermediate transmission wheel four (18) are respectively arranged between the bottle conveying wheel two (4) and the horizontal plug device (10).

6. The aseptic dispensing tray-type sampling and weighing continuous dispensing machine for powder injections according to claim 5, characterized in that: The rotation direction of the intermediate transmission wheel one (15) is opposite to that of the bottle conveying wheel two (4), intermediate transmission wheel two (16), and intermediate transmission wheel four (18).

7. The aseptic dispensing tray-type sampling and weighing continuous dispensing machine for powder injections according to claim 1, characterized in that: The plugging device (13) is a storage bin, and the bottom of the storage bin is connected to a discharge pipe.

8. The aseptic dispensing tray-type sampling and weighing continuous dispensing machine for powder injections according to claim 1, characterized in that: The powder feeding device (7) is equipped with a sterile powder feeding screw and dispensing head.

Images