Cancer cell culture device for liver cancer research

Abstract

The utility model discloses a cancer cell culture device for liver cancer research, which belongs to the field of cancer cell culture and comprises a culture component, the culture component comprises a culture dish, a plurality of culture tubes are detachably mounted in the culture dish at equal intervals, a top cover is clamped at the upper end of the culture dish, and a sealing convex edge is fixedly connected to the lower end of the top cover. According to the cancer cell culture device, cancer cells can be cultured in a classified mode according to needs through the arranged culture assembly, meanwhile, the sealing performance of the culture device can be guaranteed, and therefore the practicability of the culture device is enhanced; meanwhile, through mutual cooperation of the structures, all parts of the culture device can be conveniently detached, and then convenience can be provided for cleaning and replacement of all the parts.

Description

Technical Field

[0001] This utility model relates to the field of cancer cell culture, specifically a cancer cell culture device for liver cancer research. Background Technology

[0002] Non-communicable diseases are considered the leading cause of death worldwide. Cancer is the leading cause of death in these cases and one of the reasons hindering the improvement of life expectancy in various countries. The latest data shows that in 2018, liver cancer ranked seventh in incidence among all cancers globally, accounting for 4.7% of all cancers, while its mortality rate ranked second among all cancers, reaching a staggering 8.2%. China is a high-risk area for liver cancer, with approximately 55% of the world's liver cancer patients residing there. HCC, the most common subtype of liver cancer, accounts for 90% of all liver cancer cases. To facilitate research on liver cancer cells, culture devices are needed. The "liver cancer cell culture device" disclosed in application number "CN202222805834.2" represents an increasingly mature technology that "can effectively reduce the aggregation of liver cancer cells in the center and around the perimeter of the culture flask during culture." However, this culture device has the following drawbacks: While the cell culture flask structure facilitates the culture of cancer cells and prevents aggregation, its simple structure makes it difficult to classify and culture cancer cells according to research needs, and it also hinders the sealing of cancer cells, affecting culture quality and thus the practicality of the device. Therefore, it is necessary to provide a culture device that facilitates the classification of cancer cells as needed and ensures a sealed environment. Furthermore, the current culture device is inconvenient to disassemble, disinfect, and clean. Therefore, it is necessary to provide a culture device that is easy to disassemble, clean, and replace, improving ease of use. Utility Model Content

[0003] This invention provides a cancer cell culture device for liver cancer research, aiming to solve the problems of existing culture devices being inconvenient for classifying and culturing cancer cells, and also inconvenient for disassembly.

[0004] To achieve the above objectives, this utility model provides a cancer cell culture device for liver cancer research, including a culture component;

[0005] The culture assembly includes a culture dish, in which several culture tubes are detachably and equidistantly installed. A top cover is snapped onto the upper end of the culture dish, and a sealing rib is fixedly connected to the lower end of the top cover. Several sealing blocks are detachably installed at the lower end of the sealing rib, and a sealing film is provided at the lower end of each of the sealing blocks.

[0006] As a preferred embodiment of this utility model, the lower end of the sealing ridge is provided with several screw holes, and the upper ends of several sealing blocks are fixedly connected with bolts, the bolts being threaded into the inside of the screw holes.

[0007] As a preferred embodiment of this utility model, the bottom of the culture dish is provided with several slots, and the bottom of several culture tubes is fixedly connected with a locking block, which is engaged inside the slot.

[0008] As a preferred embodiment of this utility model, the bottom of the culture dish is provided with several arc-shaped grooves, and the lower ends of several culture tubes are fixedly connected with several arc-shaped pieces, and the several arc-shaped pieces are snapped into the inside of the arc-shaped grooves.

[0009] In a preferred embodiment of this invention, both the culture dish and the culture tube are made of polyethylene.

[0010] As a preferred embodiment of this utility model, the card block is made of rubber.

[0011] Compared with the prior art, the beneficial effects of this utility model are:

[0012] 1. When classifying liver cancer cells according to research needs, the corresponding number of culture tubes are first installed in a culture dish. At this time, the locking block is engaged in the locking groove, and the arc-shaped plate is inserted into the arc-shaped groove. Thus, the corresponding number of culture tubes can be installed in the culture dish. At this time, the cancer cells can be classified and cultured through several culture tubes. At the same time, the sealing ridge at the lower end of the top cover is engaged in the culture dish, and several sealing blocks are engaged in the culture tubes. With the help of the sealing film, the airtightness of the culture device can be guaranteed. Compared with the culture device in the prior art, the present invention, through the above structure, can facilitate the classification and culture of cancer cells, and at the same time ensure the airtightness of the culture device, thereby enhancing the practicality of the culture device.

[0013] 2. During disassembly, the top cover can be disassembled by first pulling out the sealing ridge and sealing block. Then, the lower end of the culture tube can be removed directly from the slot, and several arc-shaped pieces can be removed from the arc-shaped groove to disassemble several culture tubes. Compared with the culture device in the prior art, the present invention can facilitate the disassembly of the culture device through the cooperation of the above structures, thereby improving the convenience of cleaning and replacing each component. Attached Figure Description

[0014] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0015] Figure 2 This is a schematic diagram of the structure of the petri dish and culture tube of this utility model;

[0016] Figure 3 This is an anatomical diagram of the top cover structure of this utility model;

[0017] Figure 4 This is a cross-sectional view of the sealing block structure of this utility model;

[0018] Figure 5 This is a schematic diagram of the petri dish structure of this utility model;

[0019] Figure 6 This is a schematic diagram of the culture tube structure of this utility model.

[0020] In the diagram: 100, culture component; 101, culture dish; 102, culture tube; 103, top cover; 104, sealing ridge; 105, sealing block; 106, sealing membrane; 111, screw hole; 112, bolt; 121, slot; 122, locking block; 131, arc groove; 132, arc plate. Detailed Implementation

[0021] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0022] Please see Figure 1-6 This utility model provides a cancer cell culture device for liver cancer research, including a culture component 100;

[0023] The culture component 100 includes a culture dish 101, and several culture tubes 102 are detachably installed at equal intervals inside the culture dish 101. A top cover 103 is snapped onto the upper end of the culture dish 101, and a sealing ridge 104 is fixedly connected to the lower end of the top cover 103. Several sealing blocks 105 are detachably installed on the lower end of the sealing ridge 104, and a sealing membrane 106 is provided at the lower end of each of the sealing blocks 105.

[0024] In one specific embodiment, the culture component 100 not only allows for the classification and culture of cancer cells as needed, but also ensures the airtightness of the culture device, thereby enhancing its practicality. Furthermore, the combined structure facilitates the disassembly of the various components of the culture device, providing convenience for cleaning and replacement. In use, a corresponding number of culture tubes 102 are first installed at the bottom of the culture dish 101. At this time, the locking block 122 engages inside the locking groove 121. Then, the sealing ridge 104 at the lower end of the top cover 103 is engaged with the inner wall of the culture dish 101, while the sealing block 105 engages inside the culture tubes 102. The sealing block 105, in conjunction with the sealing film 106, improves the airtightness of the culture dish 101 and the culture tubes 102, thus enhancing the practicality of the culture device.

[0025] Please see Figures 2-6 The lower end of the sealing ridge 104 is provided with several screw holes 111, and the upper ends of several sealing blocks 105 are fixedly connected with bolts 112, which are threaded into the screw holes 111.

[0026] In one specific embodiment, the bolt 112 is threaded into the screw hole 111 to connect the sealing block 105 and the top cover 103. At the same time, the sealing block 105 can be disassembled by removing the bolt 112 from the screw hole 111.

[0027] Please see Figures 2-6 The bottom of the culture dish 101 has several slots 121, and the bottom of several culture tubes 102 are fixedly connected with a block 122, which is engaged inside the slot 121.

[0028] In one specific embodiment, the card block 122 is engaged inside the card slot 121 to improve the installation stability of the culture tube 102. After the card block 122 is removed, the culture tube 102 can be disassembled.

[0029] Please see Figures 2-6 The bottom of the petri dish 101 is provided with several arc-shaped grooves 131, and the lower ends of several culture tubes 102 are fixedly connected with several arc-shaped pieces 132, which are all snapped into the inside of the arc-shaped grooves 131.

[0030] In one specific embodiment, the arc-shaped piece 132 is snapped into the arc-shaped groove 131 to prevent the culture tube 102 from rotating inside the culture dish 101, thereby improving the installation stability of the culture tube 102.

[0031] Please see Figures 2-6 Both the petri dish 101 and the culture tube 102 are made of polyethylene.

[0032] In one specific embodiment, the culture dish 101 and culture tube 102 made of polyethylene can save on manufacturing costs while ensuring cleanliness.

[0033] Please see Figures 2-6 The card block 122 is made of rubber.

[0034] In one specific embodiment, the rubber-made locking block 122 can improve the ease of locking and unlocking.

[0035] Working principle: In use, firstly, select the corresponding number of culture tubes 102 as needed and install them at the bottom of the culture dish 101. At the same time, the locking block 122 is locked inside the locking groove 121. Then, the sealing protrusion 104 at the lower end of the top cover 103 is locked onto the inner wall of the culture dish 101. Subsequently, the sealing block 105 is locked into the inside of the culture tubes 102. The sealing block 105, together with the sealing film 106, can improve the sealing of the culture dish 101 and the culture tubes 102, thereby enhancing the practicality of the culture device.

[0036] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.

[0037] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A cancer cell culture device for liver cancer research, characterized in that, include: A culture assembly (100) includes a culture dish (101), wherein a plurality of culture tubes (102) are detachably and equidistantly installed inside the culture dish (101), a top cover (103) is snapped onto the upper end of the culture dish (101), and a sealing rib (104) is fixedly connected to the lower end of the top cover (103). A plurality of sealing blocks (105) are detachably installed on the lower end of the sealing rib (104), and a sealing membrane (106) is provided on the lower end of each of the sealing blocks (105).

2. The cancer cell culture device for liver cancer research according to claim 1, characterized in that: The lower end of the sealing ridge (104) is provided with several screw holes (111), and the upper ends of several sealing blocks (105) are fixedly connected with bolts (112), and the bolts (112) are threaded into the inside of the screw holes (111).

3. The cancer cell culture device for liver cancer research according to claim 1, characterized in that: The bottom of the culture dish (101) is provided with several slots (121), and the bottom of several culture tubes (102) are fixedly connected with a block (122), which is engaged inside the slot (121).

4. The cancer cell culture device for liver cancer research according to claim 1, characterized in that: The bottom of the culture dish (101) is provided with several arc-shaped grooves (131), and the lower ends of several culture tubes (102) are fixedly connected with several arc-shaped pieces (132), and the several arc-shaped pieces (132) are snapped into the inside of the arc-shaped grooves (131).

5. The cancer cell culture device for liver cancer research according to claim 1, characterized in that: Both the culture dish (101) and the culture tube (102) are made of polyethylene.

6. A cancer cell culture device for liver cancer research according to claim 3, characterized in that: The card block (122) is made of rubber.

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