Continuous chromatography device with temperature adjusting mechanism

Abstract

The utility model relates to the technical field of continuous chromatographic devices, and discloses a continuous chromatographic device with a temperature regulating mechanism, which comprises an outer box, a continuous chromatographic instrument is mounted at the bottom end in the outer box, a mounting assembly is arranged at the side end of the continuous chromatographic instrument, a heating assembly is arranged in the mounting assembly, and a temperature regulating mechanism is arranged in the outer box. The heating assembly can be quickly mounted and dismounted through the mounting assemblies, the fans can be quickly mounted, fixed and dismounted through the fixing assemblies, the heating assembly can be quickly mounted, fixed and dismounted through the mounting assemblies, the fans can be quickly mounted, fixed and dismounted through the fixing assemblies, the heating assembly can be quickly mounted, fixed and dismounted through the mounting assemblies, and the heating assembly can be quickly mounted, fixed and dismounted through the fixing assemblies. According to the device, a sample temperature adjusting mechanism of the continuous chromatograph does not need to be mounted and fixed through a plurality of screws, the mounting, dismounting and maintenance efficiency of the fan and the heating assembly is improved, any part cannot be lost, and the subsequent mounting of the fan and the heating assembly cannot be influenced.

Description

Technical Field

[0001] This utility model relates to the field of continuous chromatography apparatus technology, specifically to a continuous chromatography apparatus with a temperature control mechanism. Background Technology

[0002] Continuous chromatography is a continuous cyclic chromatography separation device. It consists of two concentric cylinders tightly clamped together on a base plate. Currently, the most rapidly developing type of continuous cyclic chromatography separation device features a continuous feed column, which is composed of two concentric cylinders clamped together on a base plate with a 1 cm gap between them. The space between the cylinders is filled with a suitable resin or gel. A series of small holes around the base plate beneath the cylinders lead to the receiver. The working principle of continuous cyclic chromatography is that the cyclic bed rotates around its central axis at a speed of 0.4–2.0 r / min. The feed solution and eluent are continuously fed from a fixed position at the top of the bed. Each component forms a helical band within the bed, and the bands are continuously collected at different outlets at the bottom due to varying operating conditions and the different adsorption capacities of each component in the solid phase.

[0003] Existing continuous chromatographs have temperature control functions, which can control the temperature of temperature-sensitive samples. This means that the sample to be tested is under specific temperature conditions before injection and detection, so as to keep the sample stable and ensure the accuracy of sample detection.

[0004] However, since the temperature control mechanism of a continuous chromatograph is usually installed and fixed with several screws, this method of fixing requires tightening several screws during disassembly and installation. Therefore, not only is the installation, disassembly and maintenance efficiency of the temperature control mechanism low, but the screws are also easy to be lost after disassembly, which can easily affect subsequent installation. Therefore, a continuous chromatograph device with a temperature control mechanism is needed to solve the above problems. Utility Model Content

[0005] The purpose of this invention is to provide a continuous chromatography device with a temperature control mechanism, which solves the problem that in the prior art, the temperature control mechanism of a continuous chromatograph is generally installed and fixed by several screws. This fixing method requires tightening several screws during disassembly and installation, which not only makes the installation, disassembly and maintenance of the temperature control mechanism inefficient, but also makes it easy for screws to be lost after disassembly, thus affecting subsequent installation.

[0006] This utility model provides the following technical solution: a continuous chromatography device with a temperature regulation mechanism, including an outer casing, a continuous chromatograph installed at the bottom of the inner side of the outer casing, a cover plate installed at the top of the outer casing, a mounting assembly provided at the side of the continuous chromatograph, a heating assembly provided inside the mounting assembly, mounting openings provided around the outer casing, a fan provided inside each mounting opening, and several circular grooves provided inside the outer casing, with a fixing assembly for fixing the fan provided from the inside of each circular groove to the outer end of the outer casing.

[0007] With the above scheme, the installation components allow for quick installation and disassembly of the heating components, and the fixing components allow for quick installation, fixing, and disassembly of the fan. Therefore, this device eliminates the need for multiple screws to fix the sample temperature adjustment mechanism of the continuous chromatograph. This not only improves the efficiency of installation, disassembly, and maintenance of the fan and heating components, but also prevents the loss of any parts, thus not affecting the subsequent installation of the fan and heating components.

[0008] As a preferred embodiment of the above technical solution, the installation assembly includes an inner frame plate, which is installed on the outer side of the continuous chromatograph. An outer frame plate is fixedly connected to the bottom of the outer casing. The outer frame plate is located at the outer end of the inner frame plate. Grooves are provided on both the side end of the outer frame plate and the side end of the inner frame plate. Elastic clips are fixedly connected to the top side end of both the outer frame plate and the top side end of the inner frame plate.

[0009] The above scheme, with its outer frame plate, inner frame plate, and elastic clips, is used to install the heating assembly.

[0010] As a preferred embodiment of the above technical solution, each of the elastic clips is arc-shaped.

[0011] With the above solution, since the elastic clips are all arc-shaped, it is easy to install the heating component between the outer frame plate and the inner frame plate, and at the same time, it also has the effect of limiting the position of the heating component.

[0012] As a preferred embodiment of the above technical solution, the heating component includes a heating wire, and a frame-shaped fixing plate is fixedly connected to both the top and bottom ends of the heating wire, with the heating wire located between the outer frame plate and the inner frame plate.

[0013] With the above method, the frame-shaped fixing plate is inserted between each pair of elastic clips. Since the spring clips are arc-shaped, the fixing plate can easily enter between the two pairs of elastic clips. At this time, the two pairs of elastic clips are opened by the pressure of the fixing plate. Then, the heating wire and the fixing plate can be inserted between the outer frame plate and the inner frame plate, which facilitates the installation of the heating wire.

[0014] As a preferred embodiment of the above technical solution, an outer plate is fixedly connected to the outer end of the fan, and a number of insertion holes are opened on the side end of the outer plate.

[0015] The above design, with its outer panel and sockets, facilitates the installation, fixing, or disassembly of the fan by adapting to mounting components.

[0016] As a preferred embodiment of the above technical solution, the fixing component includes a circular plate located within a circular groove. A circular rod is fixedly connected to the side end of the circular plate, and the side end of the circular rod extends through to the outer end of the outer casing. A side plate is fixedly connected to the side end of the circular rod, and a plug rod is fixedly connected to the side end of the side plate. A spring is sleeved on the outer end of the circular rod, and one end of the spring is fixedly connected to the side end of the circular plate. The plug rod is adapted to the insertion hole.

[0017] By rotating and pulling each side plate simultaneously, the fan is finely adjusted so that the insertion holes on the outer plate align with the insertion rods on each side plate. When the side plate is released, the spring pushes against the circular plate and rebounds, causing the circular rod and side plate to move, allowing the insertion rod to be inserted into the insertion hole, thereby fixing the two sides of the outer plate. This facilitates the fixing of the fan. Subsequently, the fan can be easily disassembled by pulling and rotating the side plate.

[0018] As a preferred embodiment of the above technical solution, the continuous chromatograph has several air inlets at its bottom side and several ventilation openings at its top side.

[0019] With the above scheme, the air inlet is used for temperature-controlled air to enter the continuous chromatograph, and the ventilation outlet is used for air circulation inside the continuous chromatograph.

[0020] Compared with the prior art, the beneficial effects of this utility model are:

[0021] This invention allows for the rapid installation and disassembly of the heating component via the installation assembly, and the rapid installation, fixation, and disassembly of the fan via the fixing assembly. Therefore, this device eliminates the need for multiple screws to install and fix the sample temperature adjustment mechanism of the continuous chromatograph. It not only improves the efficiency of installation, disassembly, and maintenance of the fan and heating component, but also prevents the loss of any parts, thus not affecting the subsequent installation of the fan and heating component. Attached Figure Description

[0022] Figure 1 This is a cross-sectional schematic diagram of a continuous chromatography apparatus with a temperature control mechanism;

[0023] Figure 2 for Figure 1 A magnified schematic diagram of the structure of part A in the diagram;

[0024] Figure 3 for Figure 1 A magnified schematic diagram of the partial structure of B in the diagram;

[0025] Figure 4 This is a side view schematic diagram of a continuous chromatography apparatus with a temperature control mechanism.

[0026] In the diagram: 1. Outer casing; 101. Circular groove; 2. Continuous chromatograph; 201. Air inlet; 202. Ventilation outlet; 3. Inner frame plate; 301. Outer frame plate; 302. Groove opening; 303. Elastic clip; 4. Heating wire; 401. Fixing plate; 5. Fan; 501. Outer plate; 502. Insertion hole; 6. Circular plate; 601. Circular rod; 602. Spring; 603. Side plate; 604. Insertion rod; 7. Cover plate. Detailed Implementation

[0027] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present invention.

[0028] like Figure 1-4 As shown, this utility model provides a technical solution: a continuous chromatography device with a temperature regulation mechanism, including an outer casing 1. A continuous chromatograph 2 is installed at the bottom of the outer casing 1. Several air inlets 201 are opened on the bottom side of the continuous chromatograph 2 for temperature-regulated air to enter the continuous chromatograph 2. Several ventilation openings 202 are opened on the top side of the continuous chromatograph 2 for air circulation inside the continuous chromatograph 2. A cover plate 7 is installed on the top of the outer casing 1 for sealing the top of the outer casing 1. An installation assembly is provided on the side of the continuous chromatograph 2, and a heating assembly is provided inside the installation assembly. Installation openings are opened on all four sides of the outer casing 1. A fan 5 is installed inside each installation opening. An outer plate 501 is fixedly connected to the outer end of the fan 5. Several insertion holes 502 are opened on the side of the outer plate 501. The interior of the outer casing 1 is provided with... There are several circular slots 101, and each circular slot 101 has a fixing component for fixing the fan 5 from its interior to its outer end of the outer casing 1. The heating component can be quickly installed and removed by installing the component. The heating component controls the temperature by adjusting the current, thereby achieving constant temperature heating. When the fan 5 is started, the fan 5 blows air towards the heating component, and the temperature is quickly transferred from the periphery of the continuous chromatograph 2 through the air inlet 201 into the interior of the continuous chromatograph 2, which facilitates the temperature adjustment of the sample. The fan 5 can be quickly installed, fixed and removed by the fixing component. Therefore, this device does not require the installation and fixing of the sample temperature adjustment mechanism of the continuous chromatograph 2 with several screws. It not only improves the installation, disassembly and maintenance efficiency of the fan 5 and the heating component, but also does not cause any loss of parts, so as not to affect the subsequent installation of the fan 5 and the heating component.

[0029] As one implementation method in this embodiment, such as Figure 1 and Figure 2 As shown, the mounting assembly includes an inner frame plate 3, which is installed on the outer side of the continuous chromatograph 2. An outer frame plate 301 is fixedly connected to the bottom of the outer casing 1, located at the outer end of the inner frame plate 3. Grooves 302 are provided on both the side ends of the outer frame plate 301 and the inner frame plate 3. Elastic clips 303 are fixedly connected to the top side ends of both the outer frame plate 301 and the inner frame plate 3, each clip being arc-shaped. The heating assembly includes a heating wire 4, with a frame-shaped fixing plate 401 fixedly connected to both the top and bottom ends of the heating wire 4. The heating wire 4 is located between the outer frame plate 301 and the inner frame plate 3. In practice, by inserting the frame-shaped fixing plate 401... The spring 602 is inserted between each pair of elastic clips 303. Since the spring clips are arc-shaped, the fixing plate 401 can easily enter between the two pairs of elastic clips 303. At this time, the two pairs of elastic clips 303 are opened by the pressure of the fixing plate 401. The heating wire 4 and the fixing plate 401 can then be inserted between the outer frame plate 301 and the inner frame plate 3, which facilitates the installation of the heating wire 4. Since the top of the fixing plate 401 is equipped with a handle (not shown), it is convenient to remove the heating wire 4. The heating wire 4 can be quickly installed or removed by inserting and pulling, which improves the efficiency of the installation and removal of the heating wire 4, facilitates the maintenance of the heating wire 4, and improves maintenance efficiency.

[0030] As one implementation method in this embodiment, such as Figure 1 and Figure 3 As shown, the fixing assembly includes a circular plate 6 located within a circular groove 101. A circular rod 601 is fixedly connected to the side end of the circular plate 6, extending through to the outer end of the outer casing 1. A side plate 603 is fixedly connected to the side end of the circular rod 601, and an insertion rod 604 is fixedly connected to the side end of the side plate 603. A spring 602 is sleeved on the outer end of the circular rod 601, with one end of the spring 602 fixedly connected to the side end of the circular plate 6. The insertion rod 604 is adapted to the insertion hole 502. In practice, each fan 5 is inserted into the mounting hole, and then each side plate 603 is rotated while each side plate 604 is pulled. 3. At this time, the fan 5 is finely adjusted so that the insertion hole 502 on the side end of the outer plate 501 corresponds to the insertion rod 604 on the side end of each side plate 603. After the side plate 603 is released, the spring 602 pushes against the round plate 6 to rebound, driving the round rod 601 and the side plate 603 to move, so that the insertion rod 604 is inserted into the insertion hole 502, thereby fixing the two sides of the outer plate 501, which facilitates the fixing of the fan 5. Subsequently, by pulling the side plate 603 and rotating the side plate 603, the fan 5 can be easily disassembled, which improves the installation and disassembly efficiency of the fan 5, facilitates the maintenance of the fan 5, and improves maintenance efficiency.

[0031] Working principle: By inserting the frame-shaped fixing plate 401 between each pair of elastic clips 303, the spring 602 clips, with their arc-shaped shape, facilitates the insertion of the fixing plate 401 between the two sets of elastic clips 303. The two sets of elastic clips 303 are then opened by the pressure of the fixing plate 401, allowing the heating wire 4 and the fixing plate 401 to be inserted between the outer frame plate 301 and the inner frame plate 3, thus facilitating the installation of the heating wire 4. Since the fixing plate 401 has a handle (not shown) at its top, it facilitates the subsequent removal of the heating wire 4. The heating wire 4 can be quickly installed or removed by inserting and pulling. Each fan 5 is inserted into its mounting port. Then, by rotating each side plate 603 while pulling it, the fan 5 is finely adjusted so that the insertion hole 502 on the side of the outer plate 501 aligns with the insertion rod 604 on the side of each side plate 603. After releasing the side plate 603, the spring... 602 springs back against the circular plate 6, causing the circular rod 601 and side plate 603 to move, allowing the insertion rod 604 to be inserted into the insertion hole 502, thereby fixing the two sides of the outer plate 501, thus facilitating the fixing of the blower 5. Subsequently, by pulling and rotating the side plate 603, the blower 5 can be easily disassembled. This device controls the temperature of the heating wire 4 by adjusting the current, thereby achieving constant temperature heating. By starting the blower 5, the blower 5 blows air towards the heating wire 4, rapidly transferring the temperature from the periphery of the continuous chromatograph 2 through the air inlet 201 into the continuous chromatograph 2 to regulate the sample temperature. Therefore, this device does not require the installation and fixing of the sample temperature regulation mechanism of the continuous chromatograph 2 with several screws, which not only improves the installation, disassembly, and maintenance efficiency of the blower 5 and heating wire 4, but also prevents the loss of any parts, thus not affecting the subsequent installation of the blower 5 and heating wire 4.

[0032] The above embodiments are only used to illustrate the technical solution of this utility model, and are not intended to limit it.

Claims

1. A continuous chromatography apparatus with a temperature control mechanism, comprising an outer casing (1), characterized in that: A continuous chromatograph (2) is installed at the bottom of the inner casing (1). A cover plate (7) is installed at the top of the outer casing (1). An installation assembly is provided on the side of the continuous chromatograph (2). A heating assembly is provided inside the installation assembly. Installation ports are provided around the outer casing (1). A fan (5) is provided inside each installation port. Several circular grooves (101) are provided inside the outer casing (1). A fixing assembly for fixing the fan (5) is provided from the inside of each circular groove (101) to the outer end of the outer casing (1).

2. The continuous chromatography apparatus with a temperature control mechanism according to claim 1, characterized in that: The mounting assembly includes an inner frame plate (3), which is installed on the outer side of the continuous chromatograph (2). An outer frame plate (301) is fixedly connected to the bottom of the outer casing (1). The outer frame plate (301) is located at the outer end of the inner frame plate (3). A slot (302) is provided on both the side end of the outer frame plate (301) and the side end of the inner frame plate (3). An elastic clip (303) is fixedly connected to both the top side end of the outer frame plate (301) and the top side end of the inner frame plate (3).

3. A continuous chromatography apparatus with a temperature control mechanism according to claim 2, characterized in that: Each of the elastic clips (303) is arc-shaped.

4. A continuous chromatography apparatus with a temperature control mechanism according to claim 2, characterized in that: The heating assembly includes a heating wire (4), and a frame-shaped fixing plate (401) is fixedly connected to both the top and bottom ends of the heating wire (4). The heating wire (4) is located between the outer frame plate (301) and the inner frame plate (3).

5. A continuous chromatography apparatus with a temperature control mechanism according to claim 1, characterized in that: The outer end of the fan (5) is fixedly connected to an outer plate (501), and the side end of the outer plate (501) is provided with several insertion holes (502).

6. A continuous chromatography apparatus with a temperature control mechanism according to claim 1, characterized in that: The fixing assembly includes a circular plate (6) located in a circular groove (101). A circular rod (601) is fixedly connected to the side end of the circular plate (6). The side end of the circular rod (601) extends to the outer end of the outer casing (1). A side plate (603) is fixedly connected to the side end of the circular rod (601). A plug rod (604) is fixedly connected to the side end of the side plate (603). A spring (602) is sleeved on the outer end of the circular rod (601). One end of the spring (602) is fixedly connected to the side end of the circular plate (6). The plug rod (604) is adapted to the insertion hole (502).

7. A continuous chromatography apparatus with a temperature control mechanism according to claim 1, characterized in that: The continuous chromatograph (2) has several air inlets (201) at the bottom side and several ventilation openings (202) at the top side.

Images