Brucellosis test tube agglutination test device

By designing rotation, transmission, and vibration mechanisms, rapid mixing of Brucella and serum was achieved, solving the problem of long waiting time in existing technologies and improving experimental efficiency.

CN223505184UActive Publication Date: 2025-11-04QINGHAI PROVINCIAL INST FOR ENDEMIC DISEASE CONTROL & PREVENTION
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Patent Information

Application Number
CN202423062460.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-12
Publication Date
2025-11-04
Estimated Expiration
2034-12-12

AI Technical Summary

Technical Problem

Existing brucellosis tube agglutination test devices require a long waiting time after incubation before observation can be performed, which makes it impossible to efficiently and quickly mix Brucella and serum, resulting in a significant waste of time.

Method used

A device comprising a rotating mechanism, a transmission mechanism, a shaking mechanism, and a vibration mechanism was designed. The rotating rod is driven by a rotating motor to drive the transmission rod and the shaking rod, thereby shaking and vibrating the test tube to promote the mixing of Brucella and serum.

Benefits of technology

By mixing through shaking and vibration, the time required to mix Brucella with serum is significantly reduced, thus improving experimental efficiency.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of pathogenic biology experiment devices, in particular to a brucellosis test tube agglutination test device which comprises a base, the top of the base is movably connected with the bottom of a rotating mechanism in a clamped mode, and the rotating mechanism is composed of a rotating motor, a rotating rod, a rotating disc and a connecting rod. The outer wall of the rotating mechanism is rotationally connected with the inner wall of the transmission mechanism, a rotating rod is driven to rotate through a coupler and a rotating rotating motor, the rotating rod rotates to drive a rotating disc to rotate, the rotating rotating disc rotates to drive a connecting rod to do circular motion, and the circular motion of the connecting rod drives a transmission rod to do turnover motion through a transmission connecting plate. The transmission rod rotates to drive the transmission disc to rotate, the transmission disc rotates to drive the shaking rotating rod to rotate, the shaking rotating rod rotates to drive the shaking mounting frame to rotate, the shaking mounting frame rotates to drive the test tube body to shake through the shaking top plate, the test tube body shakes to mix Brucella and serum inside, and the mixing time is shortened.
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Description

Technical Field

[0001] This utility model relates to the technical field of experimental devices for pathogenic biology, specifically a test tube agglutination test device for brucellosis. Background Technology

[0002] Brucellosis is a zoonotic infectious disease caused by Brucella bacteria. It is a natural focal infectious disease caused by various types of Brucella bacteria. After Brucella enters the human body through the skin or mucous membranes, it is phagocytosed by phagocytes and travels to local lymph nodes via the lymphatic system. If the phagocytes fail to kill the bacteria, they grow and multiply within the cells, forming a local primary lesion. The massive proliferation of bacteria within the phagocytes causes the phagocytes to rupture, and a large amount of bacteria enters the lymphatic system and blood, causing bacteremia. The bacteria travel throughout the body via the bloodstream and multiply in the mononuclear phagocyte system in the liver, spleen, lymph nodes, bone marrow, etc., forming multiple lesions. Because allergic reactions and pathogens mainly multiply within cells, antibodies and antibacterial drugs cannot easily penetrate, making it difficult to eradicate.

[0003] Most brucellosis tube agglutination test devices on the market currently require mixing a certain amount of Brucella with a series of diluted patient serums, incubating at a certain temperature, and then observing the results to determine whether the tested serum contains corresponding antibodies and their titers. However, after incubation, a long time is required for Brucella to mix with the serum, which wastes a lot of waiting time. Utility Model Content

[0004] The purpose of this invention is to provide a brucellosis tube agglutination test device to solve the problem in the background art where a long waiting time is required after incubation for Brucella to mix with serum, resulting in a significant waste of time. To achieve the above objective, this invention provides the following technical solution: a brucellosis tube agglutination test device, comprising a base, the top of which is movably engaged with the bottom of a rotating mechanism. The rotating mechanism consists of a rotating motor, a rotating rod, a rotating disk, and a connecting rod. The outer wall of the rotating mechanism is rotatably connected to the inner wall of a transmission mechanism. The transmission mechanism includes a transmission connecting plate, a transmission rod, and a transmission disk. The back of the transmission mechanism is movably engaged with the front of a shaking mechanism. The shaking mechanism consists of two shaking rotating rods, a shaking inclined plate, a shaking mounting frame, a shaking fixing plate, a shaking top plate, and a test tube body.

[0005] The outer wall of the shaking mechanism is rotatably connected to the inner wall of the base, one side of the shaking mechanism is movably abutting against one side of the vibration mechanism, and the outer wall of the vibration mechanism is rotatably connected to the inner wall of the base.

[0006] Preferably, the base includes a base plate, a motor base, and two support columns. The top of the base plate near the front is fixedly connected to the bottom of the motor base, and the top of the base plate near the front and the top of the back are respectively fixedly connected to the bottom of the two support columns. The front of the two support columns near the top is provided with a shaking through hole, and the front of the top of one of the support columns is provided with a vibration through hole.

[0007] Preferably, the bottom of the rotating motor is movably engaged with the top of the motor base, and one end of the rotating motor is fixedly connected to one end of the rotating rod via a coupling. The outer wall of the other end of the rotating rod is movably engaged with the inner wall of the rotating disk, and the back of the rotating disk near the outer wall is fixedly connected to one end of the connecting rod.

[0008] Preferably, the front side of the bottom of the transmission connecting plate is provided with a transmission through hole, and the inner wall of the transmission through hole is rotatably connected to the outer wall of the connecting rod. The outer wall of the top of the transmission connecting plate is provided with a connecting through hole, and the inner wall of the connecting through hole is rotatably connected to the outer wall of one end of the transmission rod. The other end of the transmission rod is fixedly connected to the back side of the transmission disc near the outer wall.

[0009] Preferably, one end of one of the swaying rods is movably engaged with the back of the transmission disc, and the outer walls of one end of each of the two swaying rods are rotatably connected to the inner walls of the two swaying through holes, respectively. The outer wall of one end of the other swaying rod is fixedly connected to one side of the swaying inclined plate, and the outer wall of the swaying mounting frame is provided with two flip-through holes, the inner walls of the two flip-through holes are rotatably connected to the outer walls of the other ends of the two swaying rods, and the inner wall of the middle part of the swaying mounting frame is fixedly connected to the outer wall of the swaying fixed plate. The top of the swaying mounting frame is movably engaged with the bottom of the swaying top plate, and the top of the swaying top plate is provided with a test tube mounting through hole. The inner wall of the test tube mounting through hole is movably sleeved with the outer wall of the test tube body, and the number of test tube mounting through holes and test tube bodies is several.

[0010] Preferably, the vibration mechanism includes a vibration abutment, a vibration link, a vibration spring, and a vibration baffle. One side of the vibration abutment is movably abutted against one side of the swaying inclined plate, and the inner wall of the vibration abutment is movably engaged with the outer wall of the vibration link near one end. The outer wall of the vibration link near one end is movably sleeved with the inner wall of the vibration spring, and the other end of the vibration link is fixedly connected to the front of the vibration baffle. The outer wall of the vibration link near the other end is movably sleeved with the inner wall of the vibration through hole, and one end of the vibration link is movably abutted against the outer wall of the swaying mounting bracket.

[0011] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0012] In this invention, by starting a rotating motor, the rotating motor drives a rotating rod to rotate via a coupling. The rotating rod rotates, causing a rotating disk to rotate. The rotating disk rotates, causing a connecting rod to move in a circular motion. The circular motion of the connecting rod drives a transmission rod to rotate via a transmission plate. The rotation of the transmission rod drives a transmission disk to rotate. The rotation of the transmission disk drives a wobbling rod to rotate. The rotation of the wobbling rod drives a wobbling mounting frame to rotate. The rotation of the wobbling mounting frame drives the test tube body to shake via a wobbling top plate. The shaking of the test tube body can mix the Brucella and serum inside, reducing the time required for mixing.

[0013] In this invention, the rotating rod drives the swaying inclined plate to flip, and the flipping motion of the swaying inclined plate drives the vibrating abutment plate to move linearly through the inclined surface. The linear motion of the vibrating abutment plate drives the vibrating connecting rod to move linearly. After passing the swaying inclined plate, the linearly moving vibrating connecting rod drives the vibrating baffle to move linearly through the vibrating spring. The linear motion of the vibrating baffle drives the vibrating connecting rod to strike the swaying mounting frame, generating vibration, which can accelerate the mixing between Brucella and serum. Attached Figure Description

[0014] Figure 1 This is a cross-sectional view of the present invention;

[0015] Figure 2 This is a schematic diagram of the overall structure of this utility model;

[0016] Figure 3 This is an exploded view of the present invention;

[0017] Figure 4 This is an exploded view of the rotating mechanism in this utility model;

[0018] Figure 5 This is an exploded view of the transmission mechanism in this utility model;

[0019] Figure 6 This is an exploded view of the swaying mechanism in this utility model;

[0020] Figure 7 This is an exploded view of the vibration mechanism in this utility model.

[0021] In the diagram: 1. Base; 101. Base plate; 102. Motor base; 103. Support column; 2. Rotating mechanism; 201. Rotating motor; 202. Rotating rod; 203. Rotating disk; 204. Connecting rod; 3. Transmission mechanism; 301. Transmission connecting plate; 302. Transmission rod; 303. Transmission disk; 4. Shaking mechanism; 401. Shaking rotating rod; 402. Shaking inclined plate; 403. Shaking mounting bracket; 404. Shaking fixed plate; 405. Shaking top plate; 406. Test tube body; 5. Vibration mechanism; 501. Vibration damper; 502. Vibration connecting rod; 503. Vibration spring; 504. Vibration baffle. Detailed Implementation

[0022] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of the present utility model.

[0023] Please see Figures 1 to 7 This utility model provides a technical solution: a brucellosis tube agglutination test device, including a base 1, the top of the base 1 being movably engaged with the bottom of a rotating mechanism 2, the rotating mechanism 2 being composed of a rotating motor 201, a rotating rod 202, a rotating disk 203 and a connecting rod 204, the outer wall of the rotating mechanism 2 being rotatably connected to the inner wall of a transmission mechanism 3, the transmission mechanism 3 being composed of a transmission connecting plate 301, a transmission rod 302 and a transmission disk 303, the back of the transmission mechanism 3 being movably engaged with the front of a shaking mechanism 4, the shaking mechanism 4 being composed of two shaking rotating rods 401, a shaking inclined plate 402, a shaking mounting bracket 403, a shaking fixing plate 404, a shaking top plate 405 and a test tube body 406;

[0024] The outer wall of the shaking mechanism 4 is rotatably connected to the inner wall of the base 1, one side of the shaking mechanism 4 is movablely abutting against one side of the vibration mechanism 5, and the outer wall of the vibration mechanism 5 is rotatably connected to the inner wall of the base 1.

[0025] In this embodiment, as Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 and Figure 7 As shown, the base 1 includes a base plate 101, a motor base 102, and two support columns 103. The top of the base plate 101 near the front is fixedly connected to the bottom of the motor base 102, and the top of the base plate 101 near the front and the top of the back are respectively fixedly connected to the bottom of the two support columns 103. The front of the two support columns 103 near the top is provided with a shaking through hole, and the front of the top of one of the support columns 103 is provided with a vibration through hole. The support columns 103 can keep the device stable during operation.

[0026] In this embodiment, as Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 and Figure 7As shown, the bottom of the rotating motor 201 is movably engaged with the top of the motor base 102, and one end of the rotating motor 201 is fixedly connected to one end of the rotating rod 202 through a coupling. The outer wall of the other end of the rotating rod 202 is movably engaged with the inner wall of the rotating disk 203, and the back of the rotating disk 203 near the outer wall is fixedly connected to one end of the connecting rod 204. When the rotating motor 201 is started, the rotating motor 201 drives the rotating rod 202 to rotate through the coupling. The rotation of the rotating rod 202 drives the rotating disk 203 to rotate, and the rotation of the rotating disk 203 drives the connecting rod 204 to move in a circular motion.

[0027] In this embodiment, as Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 and Figure 7 As shown, a transmission through hole is provided on the front side of the bottom of the transmission connecting plate 301, and the inner wall of the transmission through hole is rotatably connected to the outer wall of the connecting rod 204. A connection through hole is provided on the outer wall of the top of the transmission connecting plate 301, and the inner wall of the connection through hole is rotatably connected to the outer wall of one end of the transmission rod 302. The other end of the transmission rod 302 is fixedly connected to the outer wall of the transmission disk 303 near the other end. The other end of the transmission rod 302 is fixedly connected to the back side of the transmission disk 303 near the outer wall. The circumferential movement of the connecting rod 204 drives the transmission rod 302 to rotate through the transmission connecting plate 301. The rotation of the transmission rod 302 drives the transmission disk 303 to rotate.

[0028] In this embodiment, as Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 and Figure 7As shown, one end of one of the rocking rods 401 is movably engaged with the back of the transmission disc 303, and the outer walls of one end of the two rocking rods 401 are rotatably connected to the inner walls of the two rocking through holes, respectively. The outer wall of one end of the other rocking rod 401 is fixedly connected to one side of the rocking inclined plate 402, and the outer wall of the rocking mounting bracket 403 is provided with two flip through holes, the inner walls of the two flip through holes are rotatably connected to the outer walls of the other ends of the two rocking rods 401, and the inner wall of the middle part of the rocking mounting bracket 403 is fixedly connected to the outer wall of the rocking fixing plate 404. The top of the rocking mounting bracket 403 is connected to the rocking... The bottom of the top plate 405 is movably latched, and the top of the shaking top plate 405 is provided with test tube mounting through holes. The inner wall of the test tube mounting through holes is movably sleeved with the outer wall of the test tube body 406. There are several test tube mounting through holes and test tube bodies 406. The rotation of the transmission disk 303 drives the shaking rod 401 to rotate. The rotation of the shaking rod 401 drives the shaking mounting frame 403 to rotate. The rotation of the shaking mounting frame 403 drives the test tube body 406 to shake through the shaking top plate 405. The shaking of the test tube body 406 can mix the Brucella and serum inside, reducing the mixing time.

[0029] In this embodiment, as Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 and Figure 7 As shown, the vibration mechanism 5 includes a vibration abutment 501, a vibration connecting rod 502, a vibration spring 503, and a vibration baffle 504. One side of the vibration abutment 501 movably abuts against one side of the swaying inclined plate 402, and the inner wall of the vibration abutment 501 is movably engaged with the outer wall of the vibration connecting rod 502 near one end. The outer wall of the vibration connecting rod 502 near one end is movably sleeved with the inner wall of the vibration spring 503, and the other end of the vibration connecting rod 502 is fixedly connected to the front of the vibration baffle 504. The outer wall of the vibration connecting rod 502 near the other end is movably sleeved with the inner wall of the vibration through hole, and one end of the vibration connecting rod 502... The swaying rod 401 rotates and abuts against the outer wall of the swaying mounting bracket 403, causing the swaying inclined plate 402 to flip. The flipping motion of the swaying inclined plate 402 causes the vibrating abutment 501 to move linearly through the inclined surface. The linear motion of the vibrating abutment 501 causes the vibrating connecting rod 502 to move linearly. After passing the swaying inclined plate 402, the linearly moving vibrating connecting rod 502 causes the vibrating baffle 504 to move linearly through the vibrating spring 503. The linear motion of the vibrating baffle 504 causes the vibrating connecting rod 502 to strike the swaying mounting bracket 403, generating vibration, which can accelerate the mixing between Brucella and serum.

[0030] The method of use and advantages of this utility model: The working process of this brucellosis tube agglutination test device is as follows:

[0031] like Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 6 and Figure 7 As shown, by starting the rotating motor 201, the rotating motor 201 drives the rotating rod 202 to rotate via the coupling. The rotation of the rotating rod 202 drives the rotating disk 203 to rotate. The rotation of the rotating disk 203 drives the connecting rod 204 to rotate. The rotation of the connecting rod 204 drives the transmission rod 302 to rotate via the transmission connecting plate 301. The rotation of the transmission rod 302 drives the transmission disk 303 to rotate. The rotation of the transmission disk 303 drives the wobbling rotating rod 401 to rotate. The rotation of the wobbling rotating rod 401 drives the wobbling mounting bracket 403 to rotate. The rotation of the wobbling mounting bracket 403 drives the test tube body 406 to wobble via the wobbling top plate 405. The shaking of the test tube body 406 mixes the Brucella and serum inside, reducing the mixing time. The shaking rod 401 rotates, causing the shaking inclined plate 402 to flip. The flipping motion of the shaking inclined plate 402 drives the vibrating plate 501 to move linearly through the inclined surface. The linear motion of the vibrating plate 501 drives the vibrating connecting rod 502 to move linearly. After passing the shaking inclined plate 402, the linearly moving vibrating connecting rod 502 drives the vibrating baffle 504 to move linearly through the vibrating spring 503. The linear motion of the vibrating baffle 504 drives the vibrating connecting rod 502 to strike the shaking mounting frame 403, generating vibration, which can accelerate the mixing between Brucella and serum.

[0032] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely preferred examples and are not intended to limit the utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. A brucellosis tube agglutination test apparatus, comprising a base (1), characterized in that: The top of the base (1) is movably engaged with the bottom of the rotating mechanism (2). The rotating mechanism (2) consists of a rotating motor (201), a rotating rod (202), a rotating disk (203), and a connecting rod (204). The outer wall of the rotating mechanism (2) is rotatably connected to the inner wall of the transmission mechanism (3). The transmission mechanism (3) includes a transmission connecting plate (301), a transmission rod (302), and a transmission disk (303). The back of the transmission mechanism (3) is movably engaged with the front of the shaking mechanism (4). The shaking mechanism (4) consists of two shaking rotating rods (401), a shaking inclined plate (402), a shaking mounting bracket (403), a shaking fixing plate (404), a shaking top plate (405), and a test tube body (406). The outer wall of the shaking mechanism (4) is rotatably connected to the inner wall of the base (1), one side of the shaking mechanism (4) is movablely abutting against one side of the vibration mechanism (5), and the outer wall of the vibration mechanism (5) is rotatably connected to the inner wall of the base (1).

2. The brucellosis tube agglutination test apparatus according to claim 1, characterized in that: The base (1) includes a base plate (101), a motor base (102), and two support columns (103). The top of the base plate (101) near the front is fixedly connected to the bottom of the motor base (102), and the top of the base plate (101) near the front and the top of the back are respectively fixedly connected to the bottom of the two support columns (103). The front of the two support columns (103) near the top is provided with a shaking through hole, and the front of the top of one of the support columns (103) is provided with a vibration through hole.

3. The brucellosis tube agglutination test apparatus according to claim 2, characterized in that: The bottom of the rotating motor (201) is movably engaged with the top of the motor base (102), and one end of the rotating motor (201) is fixedly connected to one end of the rotating rod (202) through a coupling. The outer wall of the other end of the rotating rod (202) is movably engaged with the inner wall of the rotating disk (203), and the back of the rotating disk (203) near the outer wall is fixedly connected to one end of the connecting rod (204).

4. The brucellosis tube agglutination test apparatus according to claim 3, characterized in that: The transmission connecting plate (301) has a transmission through hole on the front side of its bottom, and the inner wall of the transmission through hole is rotatably connected to the outer wall of the connecting rod (204). The outer wall of the top of the transmission connecting plate (301) has a connection through hole, and the inner wall of the connection through hole is rotatably connected to the outer wall of one end of the transmission rod (302). The other end of the transmission rod (302) is fixedly connected to the back side of the transmission disc (303) near the outer wall.

5. The brucellosis tube agglutination test apparatus according to claim 4, characterized in that: One end of one of the swaying rods (401) is movably engaged with the back of the transmission disc (303), and the outer walls of one end of the two swaying rods (401) are rotatably connected to the inner walls of the two swaying through holes, respectively. The outer wall of one end of the other swaying rod (401) is fixedly connected to one side of the swaying inclined plate (402), and the outer wall of the swaying mounting bracket (403) is provided with two flip-through holes, the inner walls of the two flip-through holes being respectively connected to the inner walls of the two swaying rods (401). The outer wall of the other end is rotatably connected, and the inner wall of the middle part of the swaying mounting bracket (403) is fixedly connected to the outer wall of the swaying fixing plate (404). The top of the swaying mounting bracket (403) is movably engaged with the bottom of the swaying top plate (405), and the top of the swaying top plate (405) is provided with a test tube installation through hole. The inner wall of the test tube installation through hole is movably sleeved with the outer wall of the test tube body (406), and the number of test tube installation through holes and test tube body (406) is several.

6. The brucellosis tube agglutination test apparatus according to claim 5, characterized in that: The vibration mechanism (5) includes a vibration abutment (501), a vibration connecting rod (502), a vibration spring (503), and a vibration baffle (504). One side of the vibration abutment (501) is movably abutted against one side of the swaying inclined plate (402), and the inner wall of the vibration abutment (501) is movably engaged with the outer wall of the vibration connecting rod (502) near one end. The outer wall of the vibration connecting rod (502) near one end is movably sleeved with the inner wall of the vibration spring (503), and the other end of the vibration connecting rod (502) is fixedly connected to the front of the vibration baffle (504). The outer wall of the vibration connecting rod (502) near the other end is movably sleeved with the inner wall of the vibration through hole, and one end of the vibration connecting rod (502) is movably abutted against the outer wall of the swaying mounting bracket (403).