Quantitative determination kit for carbamazepine

By employing a mounting base and control components in the carbamazepine quantitative assay kit, the problem of stable fixation of reagent tubes with different diameters was solved, achieving reagent stability and convenient operation, and ensuring the accuracy and safety of the detection.

CN223508796UActive Publication Date: 2025-11-04PULING BIOLOGY (NANJING) CO LTD
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Patent Information

Application Number
CN202423045872.8
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-11
Publication Date
2025-11-04
Estimated Expiration
2034-12-11

AI Technical Summary

Technical Problem

Existing carbamazepine quantitative assay kits cannot stably hold reagent tubes of different diameters and are prone to shaking, resulting in a limited range of applications and insufficient stability.

Method used

A carbamazepine quantitative assay kit was designed, which uses multiple mounting bases and control components, including a storage groove, a rotating roller, a coil spring, and a positioning plate. The rotating roller and the coil spring work together to achieve stable fixation of the tube body, and the positioning plate and rubber strip enhance the friction to ensure the stability of the tube body in the storage groove.

Benefits of technology

It achieves stable fixation of reagent tubes of various diameters, avoiding shaking and collisions, ensuring reagent safety and detection accuracy, reducing maintenance costs, and improving ease of use and applicability.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a carbamazepine quantitative determination kit, and particularly relates to the technical field of kits, the carbamazepine quantitative determination kit comprises a box body, a plurality of assembly seats and a sealing cover, the bottoms of the assembly seats are in bolted connection with the bottom of the box body, a pipe body and a control assembly used for stabilizing the pipe body are arranged in a top storage groove, the pipe body slides down along an inclined plane and contacts and extrudes a positioning plate, and the positioning plate is fixed on the box body. After the rotating roller overcomes the torque force of the coil spring to rotate, the moving seat slides along the wall of the mounting groove, the coil spring is stretched to store energy and the pipe body is placed in place, the coil spring releases elastic potential energy, so that the rotating roller rotates reversely to drive the moving seat and the positioning plate to move towards the center of the storage groove, and the positioning plate and the rubber strip are tightly attached to the pipe body; the pipe body is fixed, the stability is good, shaking, collision and damage of the pipe body and reagent leakage in the transportation and use process can be avoided, safety and accuracy are guaranteed, the structure is flexible, stress is uniform, the pipe body can be conveniently placed in and taken out only by overcoming certain external force, and maintenance and replacement are facilitated through the split type design.
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Description

TECHNICAL FIELD

[0001] The utility model relates to a kit technical field, concretely is a carbamazepine quantitative determination kit. BACKGROUND

[0002] Carbamazepine is mainly through inhibiting the high frequency of neuron discharge, stabilizes the nerve cell membrane of overexcitation, thereby prevents the abnormal discharge of epilepsy lesion from spreading to the surrounding normal brain tissue. It can act on various ion channels, such as blocking voltage-dependent sodium channel, and then reduces the inflow of sodium ions, makes the nerve cell membrane to be in stable state. This effect is very effective for treating partial seizure, complex partial seizure, secondary generalized tonic-clonic seizure and various types of epilepsy. For example, for partial seizure patients, carbamazepine can significantly reduce the frequency and severity of seizures;

[0003] Carbamazepine determination kit is a kind of tool for detecting the concentration of carbamazepine in biological samples (such as blood, plasma, serum, etc.), and the carbamazepine determination kit has quantitative structure, the kit will provide calibration information card loaded with the calibration curve information of the reagent batch, according to the calibration curve and the fluorescence signal intensity of sample, the concentration of carbamazepine in sample can be calculated, so as to realize quantitative detection;

[0004] The existing kit is built-in with multiple reagent tubes, but due to the limitation of the size of the hole in the box, it cannot be used for placing work of multiple different diameter tube bodies, the use range is small, and due to the sponge fixation, it is easy to appear the condition of shaking, it is not stable enough, therefore, we propose a kind of carbamazepine quantitative determination kit for solving the above problems. Utility model content

[0005] The utility model aims at solving one of the technical problems existing in prior art or related art.

[0006] Therefore, the technical scheme adopted by the utility model is as follows:

[0007] A kind of carbamazepine quantitative determination kit, including box, multiple assembly seats are built-in in the box, the top of the assembly seat is equipped with the storage groove, the tube is built-in in the storage groove, the control component for stabilizing tube is arranged in the storage groove cavity, the control component includes multiple installation grooves, the installation groove is equipped in the inner wall of storage groove, the fixed cylinder is fixedly connected on the both sides of the installation groove inner wall, the rotating roller is built-in in the installation groove, the coil spring is sleeved on the both ends of the rotating roller, the rotating roller is connected with fixed cylinder by coil spring, the rotating roller is sleeved with the motion seat in the middle part, the motion seat is fixedly connected with rotating roller at one end, the positioning plate for contacting tube is fixedly connected on the one end of motion seat close to the center of storage groove, the positioning plate is arc plate structure, the inclined surface for facilitating tube to enter storage groove is equipped on the top of positioning plate.

[0008] Preferably, the bottom of the assembly seat is fixedly connected with the bottom of the box cavity by bolts, and multiple assembly seats are evenly arranged in the box cavity.

[0009] Preferably, the top of the box is hingedly connected with a closure cover.

[0010] Preferably, multiple installation grooves are evenly distributed around the assembly seat axis, and the fixed cylinders on both sides are symmetrically distributed along the installation groove axis.

[0011] Preferably, the rotating roller extends to the inside of the fixed cylinder on both ends, and the end of the rotating roller is rotatably connected with the bottom of the fixed cylinder cavity.

[0012] Preferably, the coil springs on both ends are symmetrically distributed along the axis of the rotating roller, one end of the coil spring is fixedly connected with the rotating roller, and the other end of the coil spring is fixedly connected with the inner wall of the fixed cylinder.

[0013] Preferably, the motion seat on both sides is in sliding connection with the groove wall of the installation groove, and the end of the motion seat away from the installation groove extends to the inside of the storage groove through the installation groove.

[0014] Preferably, the positioning plate is fixedly connected with multiple evenly distributed rubber strips on the side close to the tank, and the side away from the positioning plate of the rubber strip is in contact with the tube.

[0015] By adopting the above technical scheme, the utility model has obtained the beneficial effects that:

[0016] The utility model discloses a kit includes box, a plurality of assembly seat and closure cover. Assembly seat bottom and box bottom bolt connection, its top has the control assembly and be used for stabilizing pipe body in the storage groove, at the beginning, the rotating roller is under the action of coil spring and is in specific state, and the inclined surface of positioning board faces upward. When putting the pipe body, the pipe body slides along the inclined surface, contacts and extrudes the positioning board, and the extruding force is transmitted to the rotating roller through the positioning board and the movement seat, and the rotating roller rotates and overcomes the torsional moment of coil spring, and the movement seat slides along the installation groove wall, and coil spring stretches energy storage. After the pipe body is put in place, the coil spring releases the elastic potential energy, makes the rotating roller reverse rotation, drives the movement seat and positioning board to move to the center of storage groove, and the positioning board and rubber strip closely adhere to the pipe body, fix the pipe body, and good stability can avoid the pipe body shaking, collision, damage and reagent leakage in transportation and use, guarantee safety and accuracy, and the structure is flexible and the stress is even, and a plurality of installation grooves are evenly distributed, so that the pipe body stress is even and can be fixed well at any position in the storage groove, the pipe body is convenient to place and take out, the inclined surface is convenient to put in, and only needs to overcome certain external force to take out, and the split type design is beneficial to maintenance and replacement, reduces the cost and the influence to the whole use. BRIEF DESCRIPTION OF DRAWINGS

[0017] Figure 1 It is the overall structure schematic diagram of the utility model.

[0018] Figure 2 It is the utility model Figure 1 It is the enlarged structure schematic diagram of A place in the utility model.

[0019] Figure 3 It is the assembly seat internal structure schematic diagram of the utility model.

[0020] Figure 4 It is the positioning board structure schematic diagram of the utility model.

[0021] Figure 5 It is the positioning board and pipe body assembly structure schematic diagram of the utility model.

[0022] In the drawing: 1, box;101, closure cover;2, assembly seat;201, storage groove;3, control assembly;301, installation groove;302, fixed cylinder;303, rotating roller;304, coil spring;305, movement seat;306, positioning board;307, rubber strip;308, inclined surface;4, pipe body. DETAILED DESCRIPTION

[0023] The technical scheme in the embodiments of the utility model will be apparently and completely described in combination with the drawings in the embodiments of the utility model, and apparently, the described embodiments are only a part of the embodiments of the utility model, not all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by the ordinary skill in the art without making creative labor belong to the range of protection of the utility model.

[0024] Embodiment: As Figures 1-5 The utility model provides a kind of carbamazepine quantitative determination kit, including box body 1, multiple assembly seats 2 are built-in in box body 1, and the bottom of assembly seat 2 is fixedly connected with the bottom of box body 1 inner chamber by bolt, multiple assembly seats 2 are evenly arranged in box body 1 inner chamber, and the top side of box body 1 is hinged with closed cover 101, and the top of assembly seat 2 is equipped with storage groove 201, and tube body 4 is built-in in storage groove 201, and control assembly 3 for stabilizing tube body 4 is arranged in the inner chamber of storage groove 201, and multiple split assembly seats 2 are used to fix multiple tube bodies 4, provide stability, reagent kit uses multiple split assembly seats 2 to fix tube body 4, if certain assembly seat 2 or its control assembly 3 fails, this assembly seat 2 can be individually maintained or replaced, without affecting the normal use of other assembly seats 2 and tube body 4, reduce maintenance cost and the influence to entire reagent kit use.

[0025] Further, a plurality of mounting grooves 301 are arranged in the control assembly 3, the mounting grooves 301 are arranged on the inner wall of the storage groove 201, the plurality of mounting grooves 301 are uniformly distributed around the axis of the assembly seat 2, the inner wall of the mounting groove 301 is fixedly connected with a fixed cylinder 302 on both sides, the two side fixed cylinders 302 are symmetrically distributed along the axis of the mounting groove 301, a rotating roller 303 is arranged in the mounting groove 301, the two ends of the rotating roller 303 extend into the two side fixed cylinders 302, the end of the rotating roller 303 is rotatably connected with the bottom of the inner cavity of the fixed cylinder 302, a coil spring 304 is sleeved on both ends of the rotating roller 303, the two ends of the coil spring 304 are symmetrically distributed along the axis of the rotating roller 303, a moving seat 305 is sleeved on the middle part of the rotating roller 303, one end of the moving seat 305 is fixedly connected with the rotating roller 303, the two sides of the moving seat 305 are in contact with the groove wall of the mounting groove 301, the moving seat 305 is slidably connected with the groove wall of the mounting groove 301, one end of the moving seat 305 away from the mounting groove 301 extends into the storage groove 201 through the mounting groove 301, one end of the moving seat 305 close to the center of the storage groove 201 is fixedly connected with a positioning plate 306 for contacting the pipe body 4, the positioning plate 306 is an arc plate structure, a plurality of rubber strips 307 are fixedly connected on the side of the positioning plate 306 close to the tank body, the side of the rubber strip 307 away from the positioning plate 306 is in contact with the pipe body 4, an inclined surface 308 is arranged on the top of the positioning plate 306 for facilitating the pipe body 4 to enter the storage groove 201, when the pipe body 4 is placed into the storage groove 201, the pipe body 4 will first slide downward along the inclined surface 308 arranged on the top of the positioning plate 306. As the pipe body 4 gradually enters deeper into the storage groove 201, the pipe body 4 starts to contact and press the positioning plate 306. Since the positioning plate 306 is fixedly connected with the moving seat 305, and the moving seat 305 is fixedly connected with the rotating roller 303, the pressing force of the pipe body 4 on the positioning plate 306 will be transmitted to the moving seat 305 and the rotating roller 303, under the pressing force of the pipe body 4, the rotating roller 303 starts to rotate by overcoming the torque of the coil spring 304, and drives the fixed moving seat 305 to slide along the groove wall of the mounting groove 301 away from the center of the storage groove 201. In this process, the coil spring 304 is further stretched, and more elastic potential energy is stored, after the pipe body 4 is completely placed in place, the pressing force of the pipe body 4 on the positioning plate 306 no longer changes, at this time, due to the characteristics of the coil spring 304 to restore to the initial state, the coil spring 304 will exert a reverse torque on the rotating roller 303, so that the rotating roller 303 rotates back to a certain angle, and then drives the moving seat 305 and the positioning plate 306 to move towards the center of the storage groove 201, until the positioning plate 306 is tightly attached to the outer side wall of the pipe body 4. The plurality of rubber strips 307 fixedly connected on the side of the positioning plate 306 close to the pipe body 4 will also closely contact the pipe body 4, on the one hand, the friction between the rubber strips 307 and the pipe body 4 is increased, on the other hand, the rubber strips 307 can better adapt to the contour of the pipe body 4, so that the pipe body 4 is stably fixed in the storage groove 201.

[0026] Working principle: when using this device, when there is no pipe body 4 placed in the storage groove 201, the rotating roller 303 is in the initial position state under the action of the coil spring 304. Due to the elastic properties of the coil spring 304, a certain torque force will be applied to the rotating roller 303, so that it tends to keep relatively static and the coil spring 304 is in the pre-tightening state. At this time, the one end of the motion seat 305 fixedly connected with the positioning plate 306 is located in the storage groove 201, and the inclined surface 308 of the positioning plate 306 faces upward, which facilitates the subsequent pipe body 4 to smoothly enter the storage groove 201.

[0027] When the pipe body 4 is placed into the storage groove 201, the pipe body 4 will first slide downward along the inclined surface 308 opened at the top of the positioning plate 306. As the pipe body 4 gradually enters the deeper part of the storage groove 201, the pipe body 4 begins to contact and press the positioning plate 306. Since the positioning plate 306 is fixedly connected with the motion seat 305, and the motion seat 305 is fixedly connected with the rotating roller 303, the pressing force of the pipe body 4 on the positioning plate 306 will be transmitted to the motion seat 305 and the rotating roller 303. Under the action of the pressing force of the pipe body 4, the rotating roller 303 overcomes the torque of the coil spring 304 and begins to rotate, driving the motion seat 305 fixedly connected therewith to slide along the groove wall of the mounting groove 301 away from the center of the storage groove 201. During this process, the coil spring 304 is further stretched, storing more elastic potential energy. After the pipe body 4 is completely placed in position, the pressing force of the pipe body 4 on the positioning plate 306 no longer changes. At this time, due to the characteristics of the coil spring 304 to restore to the initial state and release the elastic potential energy, the coil spring 304 will exert a reverse torque on the rotating roller 303, so that the rotating roller 303 rotates back by a certain angle, thereby driving the motion seat 305 and the positioning plate 306 to move towards the center of the storage groove 201, until the positioning plate 306 tightly abuts against the outer side wall of the pipe body 4. The multiple evenly distributed rubber strips 307 fixedly connected to the side of the positioning plate 306 close to the pipe body 4 will also tightly contact the pipe body 4, on the one hand increasing the friction between the pipe body 4 and the rubber strips 307, and on the other hand better adapting to the contour of the pipe body 4, so that the pipe body 4 is stably fixed in the storage groove 201, preventing it from shaking or toppling when the box body 1 moves.

[0028] By controlling the positioning plate 306 in the assembly 3 tightly adheres to the pipe body 4 under the action of the coil spring 304, and the rubber strip 307 assists to increase the friction and adhesion, can play a very good fixed effect on the pipe body 4. Even if the kit is jolted, shaken during transportation, or moved when taking and using, etc., the pipe body 4 can be stably placed in the storage groove 201, effectively avoiding the problems of collision between the pipe bodies 4, damage to the pipe body 4 and leakage of the reagent inside, etc., ensuring the safety and accuracy of reagent preservation and subsequent detection operation, and the installation groove 301 is uniformly distributed around the assembly seat 2 axis, which means that the pipe body 4 can be applied with stable force in multiple directions around the storage groove 201. No pipe body 4 is stressed evenly, further enhancing the stability of the fixation. Moreover, the uniformly distributed structure makes the pipe body 4 placed in any position in the storage groove 201 can be better fixed, improves the applicability, the inclined surface 308 provided on the positioning plate 306 facilitates the initial placement of the pipe body 4 in the storage groove 201, making the operation more convenient, without the need for complex alignment or additional force to smoothly place the pipe body 4. When the pipe body 4 is to be taken out, only a little external force is needed to overcome the friction between the positioning plate 306 and the pipe body 4 and the action force of the coil spring 304, so that the pipe body 4 can be smoothly taken out, the operation is simple and easy to operate, improves the convenience of the kit during use.

[0029] Obviously, those skilled in the art can make various modifications and variations to the present application without departing from the spirit and scope of the present application. Thus, if these modifications and variations of the present application fall within the scope of the claims of the present application and their equivalent technologies, the present application also intends to include these modifications and variations.

Claims

1. A carbamazepine quantitative assay kit, characterized in that, The device includes a box body (1), which has multiple mounting bases (2) inside. Each mounting base (2) has a storage slot (201) at its top. A tube (4) is housed within the storage slot (201). A control component (3) for stabilizing the tube (4) is provided within the storage slot (201). The control component (3) includes multiple mounting slots (301) on the inner wall of the storage slot (201). Fixed cylinders (302) are fixedly connected to both sides of the inner wall of the mounting slot (301). A rotating roller (303) is housed within the mounting slot (301). 3) Both ends are fitted with coil springs (304). The rotating roller (303) is connected to the fixed cylinder (302) through the coil springs (304). The rotating roller (303) is fitted with a moving seat (305) in the middle. One end of the moving seat (305) is fixedly connected to the rotating roller (303). The end of the moving seat (305) near the center of the storage groove (201) is fixedly connected to a positioning plate (306) for contacting the tube body (4). The positioning plate (306) is an arc-shaped plate structure. The top of the positioning plate (306) is provided with an inclined surface (308) to facilitate the tube body (4) entering the storage groove (201).

2. The carbamazepine quantitative assay kit according to claim 1, characterized in that, The bottom of the mounting base (2) is fixedly connected to the bottom of the inner cavity of the box body (1) by bolts, and multiple mounting bases (2) are evenly arranged in the inner cavity of the box body (1).

3. The carbamazepine quantitative assay kit according to claim 1, characterized in that, The box body (1) has a hinged cover (101) on one side of its top.

4. The carbamazepine quantitative assay kit according to claim 1, characterized in that, Multiple mounting slots (301) are evenly distributed around the axis of the mounting base (2), and the fixing cylinders (302) on both sides are symmetrically distributed along the axis of the mounting slots (301).

5. The carbamazepine quantitative assay kit according to claim 1, characterized in that, The two ends of the rotating roller (303) extend into the two fixed cylinders (302) on both sides, and the ends of the rotating roller (303) are rotatably connected to the bottom of the inner cavity of the fixed cylinder (302).

6. The carbamazepine quantitative assay kit according to claim 1, characterized in that, The coil springs (304) at both ends are symmetrically distributed along the axis of the rotating roller (303). One end of the coil spring (304) is fixedly connected to the rotating roller (303), and the other end of the coil spring (304) is fixedly connected to the inner wall of the fixed cylinder (302).

7. The carbamazepine quantitative assay kit according to claim 1, characterized in that, The two sides of the motion seat (305) are in contact with the groove wall of the mounting groove (301). The motion seat (305) is slidably connected to the groove wall of the mounting groove (301). The end of the motion seat (305) away from the mounting groove (301) extends through the mounting groove (301) into the storage groove (201).

8. A carbamazepine quantitative assay kit according to claim 1, characterized in that, The positioning plate (306) has a plurality of evenly distributed rubber strips (307) fixedly connected to the side of the tank body, and the side of the rubber strips (307) away from the positioning plate (306) is in contact with the pipe body (4).