Temperature control reaction kettle for biological compound enzyme

By using components such as heating solenoids, circulation pipes, semiconductor cooling chips, and stirring blades in the bio-enzyme reactor, the problem of unreliable temperature regulation was solved, achieving uniform temperature control within the reactor and improving reaction efficiency and safety.

CN223509886UActive Publication Date: 2025-11-04SHANGHAI ZIXING BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202422766762.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-11-13
Publication Date
2025-11-04
Estimated Expiration
2034-11-13

AI Technical Summary

Technical Problem

In existing technologies, the temperature regulation of bio-enzyme reactors is unreliable, and the reaction temperature cannot be uniformly controlled, resulting in unstable enzyme activity and low reaction efficiency.

Method used

By combining a heating solenoid and a circulation tube with a semiconductor cooling chip and a cooling fan, along with stirring blades and a temperature sensor, rapid and precise temperature control and uniform temperature distribution can be achieved.

Benefits of technology

It achieves rapid response and uniform temperature distribution within the reactor, improves the stability and consistency of the bioenzyme reaction, saves energy, and enhances reaction efficiency and safety.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a temperature control reaction kettle for a biological compound enzyme, relates to the technical field of reaction kettles, and solves the technical problems that the temperature cannot be reliably adjusted and reduced and the reaction temperature of the biological enzyme cannot be uniformly controlled in the existing technical scheme. A heat preservation box is fixedly installed on the upper wall face of the stand column, an electric heating temperature rising structure is fixedly installed in the heat preservation box, and a circulating cooling structure is installed in the heat preservation box. The temperature in the kettle can be more uniformly distributed by mounting the stirring blades and adopting a high-quality temperature control design, so that an important role is played in the stability and consistency of biological enzyme reaction, the heat exchange efficiency is improved, the reaction kettle can quickly respond to the temperature regulation requirement, and the refrigeration efficiency is also improved while the energy consumption is reduced.
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Description

Technical Field

[0001] This utility model relates to the field of reaction vessel technology, specifically a temperature-controlled reaction vessel for biological complex enzymes. Background Technology

[0002] This utility model relates to the technical field of bio-enzyme reactors, which are important equipment for bio-enzyme catalytic reactions. Their temperature control function is crucial for ensuring efficient and precise reaction processes. The reactor is equipped with precise temperature sensors and a control system that monitors the temperature inside the reactor in real time. The temperature control system automatically adjusts the heating or cooling system according to preset reaction conditions to maintain the reaction temperature within the required range. Various methods are employed, such as electric heating, steam heating, or water heating, to rapidly increase the temperature of the reaction system. Cooling methods include circulating water cooling, air cooling, or coolant cooling to control overheating risks and quickly reduce the reaction temperature. The reactor features precise temperature gradient control, making it suitable for multi-stage reactions requiring temperature changes. Intelligent systems such as PLC control are used to set temperature curves and alarm functions, ensuring automatic adjustment and alarm activation within specific temperature ranges.

[0003] The activity of biological enzymes is highly sensitive to temperature, reaching its peak within a suitable temperature range. Therefore, temperature control can optimize enzyme activity and improve reaction efficiency; stable temperature conditions help maintain a constant reaction rate, preventing enzyme inactivation or incomplete reactions due to excessively high or low temperatures; precise temperature control systems can heat or cool as needed, avoiding energy waste and improving economic efficiency; they also avoid the risk of accidents caused by improper temperature during the reaction process, improving the safety of experiments and production; and through precise temperature control, more applications of biological enzymes with different temperature tolerances can be explored, extending beyond mesophilic enzymes to include research on high-temperature or low-temperature enzymes.

[0004] Through the above functions, the temperature control and regulation of the bio-enzyme reactor can significantly improve the efficiency and safety of biological reactions, making it an indispensable and important piece of equipment in modern biotechnology and industrial applications.

[0005] Existing technical solutions have technical problems such as unreliable temperature regulation and cooling, and inability to uniformly control the temperature of biological enzyme reactions. Utility Model Content

[0006] To address the shortcomings of existing technologies, this invention provides a temperature-controlled reaction vessel for biological complex enzymes, which solves the technical problems of existing solutions that cannot reliably adjust and cool down the temperature, and cannot uniformly control the temperature of biological enzyme reactions.

[0007] To achieve the above objectives, this utility model is implemented through the following technical solution: a temperature-controlled reaction vessel for biological compound enzymes, comprising a main base, a column fixedly installed on the upper wall of the main base, an insulation box fixedly installed on the upper wall of the column, an electric heating structure fixedly installed inside the insulation box, a circulating cooling structure installed inside the insulation box, a reaction chamber fixedly installed inside the insulation box, an upper cover fixedly installed on the upper wall of the reaction chamber, a temperature sensor fixedly installed on the upper cover, and the detection end of the temperature sensor installed inside the reaction chamber.

[0008] Preferably, a first motor and a gear reducer are fixedly installed on the upper wall of the main base. The input end of the gear reducer is fixedly connected to the drive end of the first motor, and a stirring blade is fixedly installed on the output end of the gear reducer. The stirring blade is rotatably installed inside the insulation box.

[0009] Preferably, the electric heating structure includes an electric heating controller, which is fixedly installed on the side wall of the insulation box and is fixedly connected to a heating solenoid, which is wound around the outer wall of the insulation box.

[0010] Preferably, the circulating cooling structure includes a circulating pipe, which is fixedly installed inside the insulation box. A cold water tank is fixedly installed on the main base, and a circulating pump is fixedly installed inside the cold water tank. The output end of the circulating pump is connected to the lower end of the circulating pipe, and the upper end of the circulating pipe is connected to the upper end of the cold water tank.

[0011] Preferably, a refrigeration unit is fixedly installed inside the cold water tank. The refrigeration unit includes a thermoelectric cooler. The thermoelectric cooler is fixedly installed on the cold water tank with its cold end facing inward. A heat dissipation fin is fixedly installed on the hot end of the thermoelectric cooler. A cooling fan is fixedly installed on the heat dissipation fin. A deflection plate is fixedly installed inside the cold water tank. The deflection plate increases the cooling time of the cooling water in the circulation pipe and increases the contact time between the water and the cold end of the thermoelectric cooler.

[0012] Preferably, the insulated box has a vacuum chamber, a water inlet pipe is fixedly installed at the upper end of the insulated box, and a water outlet pipe is fixedly installed on the lower side wall of the insulated box, which facilitates the replacement of the water bath liquid and allows the specific heat capacity and heat exchange efficiency of the water bath liquid to be adjusted to adapt to different production processes.

[0013] Beneficial effects

[0014] This invention provides a temperature-controlled reaction vessel for bio-complex enzymes. This invention allows for rapid and precise temperature adjustment, effectively solving the problem of unreliable temperature control in existing technologies. Through the installation of stirring blades and a superior temperature control design, the temperature inside the vessel is more evenly distributed, playing a crucial role in the stability and consistency of the bio-enzyme reaction. Heating solenoids and circulation pipes are used to achieve heating and cooling respectively, thereby improving heat exchange efficiency and ensuring the reaction vessel can quickly respond to temperature adjustment requirements. Semiconductor cooling chips and a cooling fan are used for efficient heat dissipation, saving energy while also improving cooling efficiency. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the main structure of a temperature-controlled reaction vessel for biological complex enzymes according to the present invention.

[0016] In the diagram: 1. Main base; 2. Column; 3. Insulation box; 4. Reaction chamber; 5. Top cover; 6. Temperature sensor; 7. First motor; 8. Gear reducer; 9. Stirring blade; 10. Electric heating controller; 11. Heating solenoid; 12. Circulation pipe; 13. Cold water tank; 14. Circulation pump; 16. Semiconductor refrigeration chip; 17. Heat dissipation fins; 18. Cooling fan; 19. Deflection plate; 20. Vacuum chamber; 21. Water inlet pipe; 22. Water outlet pipe; Detailed Implementation

[0017] To further illustrate the technical means and effects adopted by this utility model to achieve its intended purpose, the technical solutions of this utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of this utility model. Obviously, the described embodiments are only some embodiments of this utility model, not all embodiments. Detailed description follows.

[0018] Please see Figure 1 This utility model provides a technical solution: In view of the shortcomings of the prior art, this utility model provides a temperature-controlled reaction vessel for biological complex enzymes, which solves the technical problems of existing technical solutions that cannot reliably adjust and cool down the temperature and cannot uniformly control the temperature of biological enzyme reactions.

[0019] To achieve the above objectives, this utility model is implemented through the following technical solution: a temperature-controlled reaction vessel for biological compound enzymes, comprising a main base 1, a column 2 fixedly installed on the upper wall of the main base 1, an insulation box 3 fixedly installed on the upper wall of the column 2, an electric heating structure fixedly installed inside the insulation box 3, a circulating cooling structure installed inside the insulation box 3, a reaction chamber 4 fixedly installed inside the insulation box 3, an upper cover 5 fixedly installed on the upper wall of the reaction chamber 4, a temperature sensor 6 fixedly installed on the upper cover 5, and the detection end of the temperature sensor 6 being installed inside the reaction chamber 4.

[0020] In this embodiment, a first motor 7 and a gear reducer 8 are fixedly installed on the upper wall of the main base 1. The input end of the gear reducer 8 is fixedly connected to the drive end of the first motor 7, and a stirring blade 9 is fixedly installed on the output end of the gear reducer 8. The stirring blade 9 is rotatably installed inside the insulation box 3.

[0021] In this embodiment, the electric heating structure includes an electric heating controller 10, which is fixedly installed on the side wall of the insulation box 3. The electric heating controller 10 is fixedly connected to a heating solenoid 11, which is wound around the outer wall of the insulation box 3.

[0022] In this embodiment, the circulating cooling structure includes a circulation pipe 12, which is fixedly installed inside the insulation box 3. A cold water tank 13 is fixedly installed on the main base 1. A circulation pump 14 is fixedly installed inside the cold water tank 13. The output end of the circulation pump 14 is connected to the lower end of the circulation pipe 12, and the upper end of the circulation pipe 12 is connected to the upper end of the cold water tank 13.

[0023] In this embodiment, a refrigeration unit is fixedly installed inside the cold water tank 13. The refrigeration unit includes a thermoelectric cooler 16, which is fixedly installed on the cold water tank 13 with its cold end facing inward. A heat dissipation fin 17 is fixedly installed on the hot end of the thermoelectric cooler 16, and a cooling fan 18 is fixedly installed on the heat dissipation fin 17. A deflection plate 19 is fixedly installed inside the cold water tank 13. The deflection plate 19 increases the cooling time of the cooling water in the circulation pipe 12 and increases the contact time between the water and the cold end of the thermoelectric cooler 16.

[0024] In this embodiment, a vacuum chamber 20 is provided inside the heat preservation box 3, a water inlet pipe 21 is fixedly installed at the upper end of the heat preservation box 3, and a water outlet pipe 22 is fixedly installed on the lower side wall of the heat preservation box 3, which facilitates the replacement of the water bath liquid and allows the specific heat capacity and heat exchange efficiency of the water bath liquid to be adjusted to adapt to different production processes.

[0025] Its detailed connection methods are well-known technologies in this field; such as Figure 1 As shown, check the equipment connections: ensure that all wires and pipes are connected correctly, including the heating controller 10, temperature sensor 6, circulation pump 14, and refrigeration components.

[0026] Confirm that the insulation box 3, reaction box 4 and stirring device are installed properly and without leakage or damage.

[0027] Open the top cover 5 of the reaction chamber 4, add the required bio-complex enzyme and other substrates or solutions into the reaction chamber 4, ensuring that the maximum capacity of the reaction vessel is not exceeded.

[0028] Close the top cover 5 to ensure it is tightly closed to prevent material leakage.

[0029] Set an appropriate reaction temperature range according to the specific requirements of the biological enzyme reaction.

[0030] The temperature of the heating solenoid 11 is set using the electric heating controller 10, and the electric heating and circulating cooling system is started to achieve rapid heating or cooling.

[0031] The heating solenoid 11 is started to raise the temperature, the circulating pump 14 and the semiconductor cooling chip 16 are started, and the cold end of the cooling chip continuously cools the water in the circulating pipe 12. Then, the water in the heat-insulating box 3 absorbs the heat of the water bath liquid through heat conduction to complete the cooling.

[0032] Start the first motor 7 and gear reducer 8 to rotate the stirring blade 9 at the set speed to ensure uniform temperature of the water bath liquid.

[0033] Temperature sensor 6 will monitor the temperature inside reaction chamber 4 in real time to ensure that it fluctuates stably within the set range and make corresponding adjustments through the control system.

[0034] Regularly check the reaction progress, including the state of the materials, temperature stability, and stirring conditions.

[0035] If any abnormalities occur, such as unstable temperature or equipment alarms, check and adjust immediately.

[0036] Stop heating, cool down and stir, and wait for the material in the reactor to drop to a safe temperature.

[0037] Open the top cover 5 and carefully remove the reaction product from the reaction chamber 4.

[0038] Clean reaction chamber 4 and the stirring device to ensure there are no residues, so as to guarantee cleanliness for the next use.

[0039] Regularly conduct comprehensive inspections and maintenance of the equipment, such as checking the working status of the heating solenoid 11, circulation system, and sensors, to extend the service life of the equipment.

[0040] It should be noted that in this paper, relational terms such as first and second are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations.

[0041] The above description is merely a preferred embodiment of the present utility model and is not intended to limit the present utility model in any way. Although the present utility model has been disclosed above with reference to a preferred embodiment, it is not intended to limit the present utility model. Any person skilled in the art can make some modifications or alterations to the above-disclosed technical content to create equivalent embodiments without departing from the scope of the present utility model. Any simple modifications, equivalent changes and alterations made to the above embodiments based on the technical essence of the present utility model without departing from the scope of the present utility model shall still fall within the scope of the present utility model.

Claims

1. A temperature-controlled reaction vessel for biological complex enzymes, comprising a main base (1), characterized in that, A column (2) is fixedly installed on the upper wall of the main base (1). A heat preservation box (3) is fixedly installed on the upper wall of the column (2). An electric heating structure is fixedly installed inside the heat preservation box (3). A circulating cooling structure is installed inside the heat preservation box (3). A reaction box (4) is fixedly installed inside the heat preservation box (3). An upper cover (5) is fixedly installed on the upper wall of the reaction box (4). A temperature sensor (6) is fixedly installed on the upper cover (5). The detection end of the temperature sensor (6) is installed inside the reaction box (4).

2. The temperature-controlled reaction vessel for biological complex enzymes according to claim 1, characterized in that... The main base (1) is fixedly installed with a first motor (7) and a gear reducer (8). The input end of the gear reducer (8) is fixedly connected to the drive end of the first motor (7). The output end of the gear reducer (8) is fixedly installed with a stirring blade (9). The stirring blade (9) is rotatably installed inside the insulation box (3).

3. The temperature-controlled reaction vessel for biological complex enzymes according to claim 1, characterized in that... The electric heating structure includes an electric heating controller (10), which is fixedly installed on the side wall of the insulation box (3). The electric heating controller (10) is fixedly connected to a heating solenoid (11), which is wound around the outer wall of the insulation box (3).

4. The temperature-controlled reaction vessel for biological complex enzymes according to claim 1, characterized in that... The circulating cooling structure includes a circulating pipe (12), which is fixedly installed inside the insulation box (3). A cold water tank (13) is fixedly installed on the main base (1). A circulating pump (14) is fixedly installed inside the cold water tank (13). The output end of the circulating pump (14) is connected to the lower end of the circulating pipe (12). The upper end of the circulating pipe (12) is connected to the upper end of the cold water tank (13).

5. A temperature-controlled reaction vessel for biological complex enzymes according to claim 4, characterized in that... A refrigeration unit is fixedly installed inside the cold water tank (13). The refrigeration unit includes a semiconductor refrigeration chip (16). The semiconductor refrigeration chip (16) is fixedly installed on the cold water tank (13). The cold end of the semiconductor refrigeration chip (16) faces the inside of the cold water tank (13). A heat dissipation fin (17) is fixedly installed on the hot end of the semiconductor refrigeration chip (16). A heat dissipation fan (18) is fixedly installed on the heat dissipation fin (17). A deflection plate (19) is fixedly installed inside the cold water tank (13).

6. A temperature-controlled reaction vessel for biological complex enzymes according to claim 1, characterized in that... The heat preservation box (3) has a vacuum chamber (20) inside. A water inlet pipe (21) is fixedly installed on the upper end of the heat preservation box (3), and a water outlet pipe (22) is fixedly installed on the lower side wall of the heat preservation box (3).