Exhaled gas sampling device applied to proton transfer reaction mass spectrometer

By installing a one-way inlet valve and a pulse solenoid valve in the exhaled gas injection device of the proton transfer reaction mass spectrometer, the problems of exhaled gas dilution and detection error were solved, enabling accurate collection and real-time monitoring of exhaled gas and ensuring the reliability and repeatability of experimental results.

CN223516347UActive Publication Date: 2025-11-07WULIANGYE
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Patent Information

Application Number
CN202422722643.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-11-08
Publication Date
2025-11-07
Estimated Expiration
2034-11-08

AI Technical Summary

Technical Problem

Existing proton transfer reaction mass spectrometers suffer from problems such as large dilution and detection errors and poor repeatability in exhaled gas detection due to open acquisition.

Method used

An inlet check valve is installed on the air inlet line of the mask, and a pulse solenoid valve is installed on the connecting line between the gas collection bag and the mass spectrometer. Combined with the fit of the mask and the time interval control, the sealed delivery of exhaled gas and the monitoring of target substances during the detection period are ensured.

Benefits of technology

It enables accurate collection and real-time monitoring of exhaled gases, reduces errors caused by changes in gas volume and atmospheric flow interference, and improves the reliability and repeatability of the experiment.

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Abstract

The utility model discloses an exhaled gas sampling device applied to a proton transfer reaction mass spectrometer in the technical field of exhaled gas detection. An exhaled gas sampling device applied to a proton transfer reaction mass spectrometer comprises a mask and a gas collecting bag, a gas inlet pipeline of the mask is communicated with the outside, a gas outlet pipeline of the mask is communicated with the gas inlet end of the gas collecting bag, the gas outlet end of the gas collecting bag is used for being communicated with the proton transfer reaction mass spectrometer, and a gas inlet one-way valve is arranged on the gas inlet pipeline of the mask. Air can only enter the mask from the outside through the air inlet pipeline; and a pulse electromagnetic valve is arranged on a communicating pipeline between the gas outlet end of the gas collecting bag and the proton transfer reaction mass spectrometer. According to the exhaled gas sampling device applied to the proton transfer reaction mass spectrometer, errors caused by change of the exhaled gas amount of a testee and airflow interference in the atmosphere can be eliminated, so that the reliability and repeatability of experimental results are ensured.
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Description

TECHNICAL FIELD

[0001] The utility model relates to exhaled gas detection technical field, concretely relates to a kind of exhaled gas sampling device applied to proton transfer reaction mass spectrometer. BACKGROUND

[0002] Proton transfer reaction mass spectrometer as a kind of instrument that can monitor gas change in real time, is applied to the real-time monitoring of human exhaled gas.But the current more commonly used gas collection sampling device is mask and gas collection bag, mask inlet pipeline is connected with outside atmosphere, mask outlet pipeline is connected with gas collection bag, gas collection bag and proton transfer reaction mass spectrometer are connected.Because current gas collection is open, it is easy to cause exhaled gas to be diluted by the airflow flowing in atmosphere, lead to exhaled gas cannot be collected completely, affect the repeatability of experiment, and cannot truly reflect the change trend of exhaled gas, have greater detection error.To solve this problem, a closed environment needs to be created, so that exhaled gas is completely transported to proton transfer reaction mass spectrometer, and the oxygen supply of test subject is ensured. SUMMARY

[0003] To overcome the problem that existing proton transfer reaction mass spectrometer cannot truly reflect exhaled gas and has greater detection error, the utility model provides a kind of exhaled gas sampling device applied to proton transfer reaction mass spectrometer.

[0004] The technical scheme that the utility model solves its technical problem is as follows:

[0005] Exhaled gas sampling device applied to proton transfer reaction mass spectrometer, including mask and gas collection bag, the gas inlet pipeline of mask is connected with outside, the gas outlet pipeline of mask is connected with the gas inlet end of gas collection bag, the gas outlet end of gas collection bag is used to connect with proton transfer reaction mass spectrometer, inlet check valve is arranged on the gas inlet pipeline of mask, so that gas can only enter mask from outside through gas inlet pipeline;Pulse solenoid valve is arranged on the connecting pipeline between gas collection bag gas outlet end and proton transfer reaction mass spectrometer.

[0006] In the application, inlet check valve is arranged on the gas inlet pipeline of mask, so that in the state of inhalation, inlet check valve opens, atmosphere enters mask, and the oxygen supply of test subject is ensured;In the state of exhalation, inlet check valve is closed, and the adhesion of mask is combined, so that exhaled gas enters gas collection bag through the gas outlet pipeline of mask.Through the pulse solenoid valve arranged on the connecting pipeline between gas collection bag and proton transfer reaction mass spectrometer, the human exhaled gas stored in gas collection bag in a certain time period is transported to proton transfer reaction mass spectrometer for detection in the implementation, to monitor the real-time change of target substance in human exhaled gas.Exclude the error caused by the change of test subject exhaled gas volume and airflow disturbance in atmosphere, to ensure the reliability and repeatability of experimental results.

[0007] In some embodiments, the intake one-way valve is arranged at the end of the intake pipeline inside the mask.

[0008] In some embodiments, a heat preservation box is arranged outside the gas collection bag.

[0009] In some embodiments, a strap is arranged on the mask to facilitate the wearing and fixing of the mask.

[0010] In some embodiments, an exhaust one-way valve is arranged on the exhaust pipeline of the mask, so that the gas can only enter the gas collection bag through the exhaust pipeline from the mask.

[0011] In some embodiments, the exhaust one-way valve is arranged at the end of the exhaust pipeline inside the mask.

[0012] The beneficial effects of the utility model are:

[0013] By arranging the intake one-way valve on the intake pipeline of the mask, the intake one-way valve is opened in the inhalation state, atmospheric air enters the mask, and the oxygen supply of the test subject is ensured; in the exhalation state, the intake one-way valve is closed, and the adhesion of the mask is combined, so that the exhaled gas enters the gas collection bag through the exhaust pipeline of the mask. By arranging the pulse electromagnetic valve on the communication pipeline between the gas collection bag and the proton transfer reaction mass spectrometer, the human exhaled gas stored in the gas collection bag in a certain time period is transported to the proton transfer reaction mass spectrometer for detection to monitor the real-time change of the target substance in the human exhaled gas. The error caused by the change of the test subject's exhaled gas and the air flow disturbance in the atmosphere is excluded to ensure the reliability and repeatability of the experimental results. BRIEF DESCRIPTION OF DRAWINGS

[0014] Figure 1 The structure diagram of the exhaled gas sampling device for the proton transfer reaction mass spectrometer is provided.

[0015] In the figure, 1 is a strap, 2 is a mask, 3 is an exhaust pipeline, 4 is a gas collection bag, 5 is a communication pipeline, 6 is a pulse electromagnetic valve, and 7 is an intake pipeline. DETAILED DESCRIPTION

[0016] The utility model will be further described below in combination with the drawings.

[0017] In order to make the purpose, technical scheme and advantages of the utility model more clear and obvious, the utility model will be further described in detail below in combination with the drawings and examples. It should be understood that the specific examples described herein are only used to explain the utility model, and are not used to limit the utility model.

[0018] For example, Figure 1The utility model provides a kind of exhaled gas sampling device applied to proton transfer reaction mass spectrometer.

[0019] Exhaled gas sampling device applied to proton transfer reaction mass spectrometer, including mask 2 and gas collection bag 4, the gas inlet pipeline 7 of mask 2 is communicated with outside, the gas outlet pipeline 3 of mask 2 is communicated with the gas inlet end of gas collection bag 4, the gas outlet end of gas collection bag 4 is used to communicate with proton transfer reaction mass spectrometer, gas inlet check valve (not shown in drawing) is equipped on the gas inlet pipeline 7 of mask 2, so that gas can only enter mask 2 from outside by gas inlet pipeline 7;Pulse solenoid valve 6 is equipped on the pipeline between the gas outlet end of gas collection bag 4 and proton transfer reaction mass spectrometer.

[0020] In the present application, by setting gas inlet check valve on the gas inlet pipeline 7 of mask 2, in the state of inhalation, gas inlet check valve opens, atmospheric air enters mask 2, to ensure that the subject oxygen supply is smooth;In the state of exhalation, gas inlet check valve closes, combined with the adhesion of mask 2, so that exhaled gas enters gas collection bag 4 through the gas outlet pipeline 3 of mask 2. By setting pulse solenoid valve 6 on the communication pipeline 5 between gas collection bag 4 and proton transfer reaction mass spectrometer, set time interval in implementation, the human exhaled gas stored in gas collection bag 4 in a certain time period is transported to proton transfer reaction mass spectrometer for detection, to monitor the real-time change of target substance in human exhaled gas. Excluding the error caused by the change of exhaled gas volume of the subject and the disturbance of air flow in the atmosphere, to ensure the reliability and repeatability of experimental results.

[0021] In the present embodiment, gas inlet check valve is arranged at the end of gas inlet pipeline 7 located in mask 2. Thus, the influence of the detection results caused by the residual air in gas inlet pipeline 7 is avoided.

[0022] In the present embodiment, heat preservation box (not shown in drawing) is arranged outside gas collection bag 4. Thus, the temperature of exhaled gas is maintained, and the condensation of exhaled gas caused by temperature drop is avoided, to further improve the accuracy of detection results.

[0023] In the present embodiment, strap 1 is arranged on mask 2, to facilitate the wearing and fixing of mask 2. Thus, the adhesion of mask 2 is further ensured, and the entry of outside air is avoided, to improve the accuracy of detection results.

[0024] In the present embodiment, gas outlet check valve (not shown in drawing) is arranged on the gas outlet pipeline 3 of mask 2, so that gas can only enter gas collection bag 4 from mask 2 through gas outlet pipeline 3. In the process of inhalation, the gas flow between inhalation channel and gas collection bag 4 is blocked, to improve the accuracy of detection results.

[0025] In the present embodiment, the outlet one-way valve is arranged at the end of the outlet pipeline 3 located in the mask 2. This is implemented to avoid the influence on the detection result due to the residual breath on the outlet pipeline 3.

[0026] The above merely describes the preferred embodiments of the present application and is not intended to limit the present application. Any modification, equivalent replacement and improvement within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. An apparatus for sampling exhaled breath for proton transfer reaction mass spectrometry, comprising a face mask (2) and a gas collection bag (4), the inlet line (7) of the face mask (2) being in communication with the ambient atmosphere, the outlet line (3) of the face mask (2) being in communication with the inlet end of the gas collection bag (4), the outlet end of the gas collection bag (4) being adapted for communication with a proton transfer reaction mass spectrometer, characterised in that, A one-way intake valve is arranged on the intake pipeline (7) of the mask (2) to allow gas to enter the mask (2) only from the outside through the intake pipeline (7); and a pulse electromagnetic valve (6) is arranged on the connecting pipeline (5) between the gas outlet end of the gas collection bag (4) and the proton transfer reaction mass spectrometer.

2. The breath gas sampling device for use in a proton transfer reaction mass spectrometer of claim 1, wherein, The one-way intake valve is arranged at the end of the intake pipeline (7) inside the mask (2).

3. The breath gas sampling device for use in a proton transfer reaction mass spectrometer of claim 1, wherein, An insulation box is arranged outside the gas collection bag (4).

4. The breath gas sampling device for use in a proton transfer reaction mass spectrometer of claim 1, wherein, A strap (1) is arranged on the mask (2) to facilitate the wearing and fixing of the mask (2).

5. The breath gas sampling device for use in a proton transfer reaction mass spectrometer as claimed in any one of claims 1 to 4, wherein, A one-way outlet valve is arranged on the outlet pipeline (3) of the mask (2) to allow gas to enter the gas collection bag (4) only from the mask (2) through the outlet pipeline (3).

6. The breath gas sampling device for use in a proton transfer reaction mass spectrometer of claim 5, wherein, The one-way outlet valve is arranged at the end of the outlet pipeline (3) inside the mask (2).