Chemiluminescence detection device with reagent moving mechanism

Abstract

The utility model relates to the field of chemiluminescence detection, in particular to a chemiluminescence detection device with a reagent moving mechanism. The technical problems that in the detection process of a chemiluminescence detection device, a single reagent tube is directly dropped into a container, the luminescence state reaction is observed, and the reagent tube is operated in a handheld mode, so that the dropping amount of the reagent tube every time is difficult to control, the luminescence detection state is influenced, and the overall detection effect is reduced are solved. According to the technical scheme, the chemiluminiscence detection device with the reagent moving mechanism comprises a frame sleeve, a supporting column, a movable reagent module, a dripping pipe, a balance plate and a chemiluminiscence detection assembly, the movable reagent module is arranged in the middle of the frame sleeve in a linear sliding mode and can carry a dripping pipe for dripping a test reagent, the movable reagent module is correspondingly arranged below the frame sleeve through the balance plate and is provided with a dripping reaction container for stabilizing, and the chemiluminescence detection assembly can be used for chemiluminescence detection. The overall chemiluminescence detection effect is improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to the field of chemiluminescence detection, especially to a chemiluminescence detection device with reagent moving mechanism. BACKGROUND

[0002] Chemiluminescence detection is an analysis and detection technology based on chemiluminescence phenomenon. In the chemiluminescence process, the energy released by some chemical reactions is not dissipated in the form of heat energy, but excites some molecules (usually luminophores) in the reaction system to reach the excited state. These molecules emit photons (light) in the process of returning from the excited state to the ground state, thereby producing chemiluminescence. The chemiluminescence detection device, also known as a chemiluminescence analyzer or a chemiluminescence immunoassay analyzer, is an instrument for detecting substances based on the principle of chemiluminescence. The existing chemiluminescence detection device directly drops a single reagent tube into a container during detection to observe the luminescence state reaction. The reagent tube is handheld, making it difficult to control the drop amount each time, affecting the luminescence detection state, and reducing the overall detection effect. Therefore, we propose a chemiluminescence detection device with a reagent moving mechanism to solve the problems mentioned above. SUMMARY

[0003] In order to overcome the problem that the chemiluminescence detection device directly drops a single reagent tube into a container during detection to observe the luminescence state reaction, and the reagent tube is handheld, making it difficult to control the drop amount each time, affecting the luminescence detection state, and reducing the overall detection effect.

[0004] The technical solution of the utility model is: a chemiluminescence detection device with a reagent moving mechanism, including a frame sleeve, a support column, a movable reagent module, a drop tube, a balance plate, and a chemiluminescence detection assembly. The frame sleeve is used to carry the movable reagent module for stable sliding and to keep the chemiluminescence detection mounted. The middle part of the frame sleeve is provided with a movable reagent module that can linearly slide to carry the drop tube for drop testing reagent. The middle part of the movable reagent module is provided with a drop tube that contains the drop liquid for testing. The lower part of the frame sleeve corresponds to the movable reagent module and is provided with a balance plate that carries the drop reaction container for stability. The balance plate is linearly provided with a chemiluminescence detection assembly for chemiluminescence detection. The balance plate and the frame sleeve are provided with support columns at the corners for stability.

[0005] Preferably, the movable reagent module is linearly slidingly arranged in the middle part of the frame sleeve, can carry the drop tube for drop testing reagent, and is correspondingly arranged below the frame sleeve by the balance plate. The movable reagent module is provided with a drop reaction container for stability. The chemiluminescence detection assembly is linearly arranged on the balance plate and can be used for chemiluminescence detection, improving the overall chemiluminescence detection effect.

[0006] As preferred, the frame cover comprises a U-shaped frame, a fixed plate, a sliding rail, a positioning hole, a guide hole, a protective plate, a disassembly plate, a positioning sleeve, a positioning bolt and a connecting pin, the U-shaped frame is linearly arranged in two groups, the four corners of the two groups of U-shaped frames are provided with positioning holes for supporting column insertion, the two sides of the two groups of U-shaped frames are provided with sliding rails for movable reagent module sliding, the movable box can be moved more stably through the sliding rail.

[0007] As preferred, one end of the two groups of U-shaped frames is fixedly connected with a protective plate, a guide hole is formed in the center of the protective plate, a disassembly plate is arranged at the end of the two groups of U-shaped frames away from the protective plate, positioning sleeves are symmetrically arranged on the disassembly plate, a connecting pin is arranged between the positioning sleeve and the disassembly plate, a positioning bolt is sleeved on the connecting pin, and the positioning bolt can be disassembled and adjusted.

[0008] As preferred, three groups of elastic bolts for positioning and longitudinal height adjustment of the frame cover are linearly arranged on the supporting column, and a damping base is arranged at the bottom of the supporting column.

[0009] As preferred, the movable reagent module comprises a movable box, a center hole, a sliding table, a connecting hole, a multi-hole mounting column, a limiting hole, a push rod, a gas cylinder, a high-speed camera and a display screen, the two sides of the movable box are provided with sliding tables, the rear end of the movable box is provided with a push rod, the gas cylinder drives the push rod to drive the movable box to linearly slide along the frame cover, and the movable effect is increased.

[0010] As preferred, the high-speed camera is connected with the display screen at the outer end of the high-speed camera, the center of the movable box is provided with a center hole, the periphery of the center hole is provided with a connecting hole, the inside of the center hole is provided with a multi-hole mounting column, and the inside of the multi-hole mounting column is provided with a limiting hole.

[0011] As preferred, a plurality of accommodating chemical luminescence detection assembly insertion holes are linearly arranged on the balance plate, the chemical luminescence detection assembly comprises a damping sleeve, a pressure bearing disc, a photomultiplier tube, a light interaction module and a data screen, the pressure bearing disc is sleeved with the damping sleeve, the pressure bearing disc is provided with the photomultiplier tube and the light interaction module in a ring shape, the photomultiplier tube and the light interaction module are electrically connected with the data screen, the light interaction module comprises a light detector, an electric signal amplifier, a light receiver and a controller which are electrically connected, the light detector is used for detecting photons generated by chemical reaction, the electric signal amplifier converts the light signal into an electric signal, and the electric signal is fed back to the data screen for observation.

[0012] The utility model discloses the beneficial effect:

[0013] 1. Unlike previous chemiluminescence detection devices, which involved directly dripping individual reagent tubes into a container to observe the luminescence reaction and required hand-held operation, making it difficult to control the amount dripped each time and affecting the luminescence detection state, thus reducing the overall detection effect, this new device uses a frame sleeve to support the stable sliding of a movable reagent module and maintain the chemiluminescence detection assembly. The movable reagent module, linearly slidable in the middle of the frame sleeve, carries the drip tube for dripping test reagents. A balance plate, correspondingly positioned below the frame sleeve, stabilizes the movable reagent module by holding the drip reaction container. The chemiluminescence detection assembly, linearly positioned on the balance plate, is used for chemiluminescence detection, improving the overall chemiluminescence detection effect.

[0014] 2. During testing, containers containing the corresponding solvents are placed sequentially into the holes on the balance plate to form multiple comparative experiments. The corresponding droppers containing the reaction solvent are then passed sequentially through the limiting holes in the multi-hole mounting column. A cylinder-driven push rod moves the moving box linearly along the frame until the dropper reaches the corresponding container and stops, allowing the solution to drip. A high-speed camera simultaneously observes the dripping process and displays the results on the screen. Simultaneously, the light interaction module and photomultiplier tube begin operation, along with the photodetector, electrical signal amplifier, light receiver, and controller. The photodetector detects photons generated by the chemical reaction, and the electrical signal amplifier converts the light signal into an electrical signal, which is then displayed on the data screen for observation. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0016] Figure 2 This is a schematic diagram of the frame sleeve of this utility model;

[0017] Figure 3 This is an exploded schematic diagram of the movable reagent module of this utility model;

[0018] Figure 4 This is another schematic diagram of the movable reagent module of this utility model.

[0019] Explanation of reference signs: 1, frame sleeve; 2, support column; 3, movable reagent module; 4, drop tube; 5, balance plate; 6, chemiluminescence detection assembly; 101, U-shaped frame; 102, fixed plate; 103, sliding rail; 104, positioning hole; 105, guide hole; 106, protection plate; 107, disassembly plate; 108, positioning sleeve; 109, positioning bolt; 110, connecting pin; 201, tension bolt; 202, shock absorbing base; 301, moving box; 302, center hole; 303, sliding table; 304, connecting hole; 305, multi-hole mounting column; 306, limiting hole; 307, push rod; 308, air cylinder; 309, high-speed camera; 310, display screen; 501, put-in hole; 601, shock absorbing sleeve; 602, pressure bearing disc; 603, photomultiplier tube; 604, light interaction module; 605, data screen. DETAILED DESCRIPTION

[0020] The utility model is further explained in connection with the drawings and examples.

[0021] Please refer to Figures 1-2 The utility model provides a kind of chemiluminescence detection device with reagent moving mechanism, including frame sleeve 1, support column 2, movable reagent module 3, drop tube 4, balance plate 5 and chemiluminescence detection assembly 6;For bearing movable reagent module 3 stable sliding and keep chemiluminescence detection frame sleeve 1, the middle part of frame sleeve 1 is equipped with movable reagent module 3 that can linearly slide and carry drop tube 4 to carry out drop test reagent, the middle part of movable reagent module 3 is annularly connected with drop tube 4 for containing drop liquid test, the lower part of frame sleeve 1 is equipped with balance plate 5 for carrying drop reaction container stable corresponding movable reagent module 3, balance plate 5 is linearly equipped with chemiluminescence detection assembly 6 for chemiluminescence detection, balance plate 5 and frame sleeve 1 four quarters are all equipped with support column 2 for supporting stable.

[0022] Please refer to Figures 2-4In the embodiment, the frame sleeve 1 comprises a U-shaped frame 101, a fixed plate 102, a sliding rail 103, a positioning hole 104, a guide hole 105, a protection plate 106, a disassembly plate 107, a positioning sleeve 108, a positioning bolt 109 and a connecting pin 110. The U-shaped frame 101 is linearly arranged in two groups. The four corners of the two groups of U-shaped frames 101 are provided with positioning holes 104 for inserting the support column 2. The two sides of the two groups of U-shaped frames 101 are provided with sliding rails 103 for sliding the movable reagent module 3. The movable box 301 can move more stably through the sliding rail 103. One end of the two groups of U-shaped frames 101 is fixedly connected with the protection plate 106. The center of the protection plate 106 is provided with a guide hole 105. The end of the two groups of U-shaped frames 101 away from the protection plate 106 is provided with the disassembly plate 107. The disassembly plate 107 is symmetrically provided with the positioning sleeve 108. The positioning sleeve 108 and the disassembly plate 107 are provided with the connecting pin 110. The connecting pin 110 is provided with the positioning bolt 109. The positioning bolt 109 can be disassembled and adjusted.

[0023] Please refer to Figures 3-4 In the embodiment, the support column 2 is linearly provided with three groups of elastic bolts 201 for positioning and longitudinal height adjustment of the frame sleeve 1. The bottom of the support column 2 is provided with a damping base 202. The two groups of U-shaped frames 101 can be adjusted in height along the support column 2 by the elastic bolts 201, so that the drip pipe 4 is closer to the reaction container. The movable reagent module 3 comprises a movable box 301, a center hole 302, a sliding table 303, a connecting hole 304, a multi-hole mounting column 305, a limiting hole 306, a push rod 307, a gas cylinder 308, a high-speed camera 309 and a display screen 310. The two sides of the movable box 301 are provided with the sliding table 303. The rear end of the movable box 301 is provided with the push rod 307. The gas cylinder 308 drives the push rod 307 to drive the movable box 301 to linearly slide along the frame sleeve 1. The movable box 301 is driven by the gas cylinder 308 to linearly slide along the frame sleeve 1, which increases the moving effect.

[0024] Please refer to Figures 1-4In the embodiment, the high-speed camera 309 is connected to the two sides of the bottom of the mobile box 301 and the slide platform 303, the outer end of the high-speed camera 309 is provided with a display screen 310, a center hole 302 is formed in the center of the mobile box 301, a connecting hole 304 is formed around the center hole 302, a multi-hole mounting column 305 is arranged inside the center hole 302, a limiting hole 306 is formed around the inside of the multi-hole mounting column 305, the dropping tube 4 can be inserted through the limiting hole 306, a linear accommodating hole 501 is formed in the balance plate 5 for accommodating the chemiluminescence detection assembly 6, the chemiluminescence detection assembly 6 comprises a shock-absorbing sleeve 601, a pressure-bearing disc 602, a photomultiplier tube 603, a light interaction module 604 and a data screen 605, the shock-absorbing sleeve 601 is arranged on the outer side of the pressure-bearing disc 602, the photomultiplier tube 603 and the light interaction module 604 are arranged around the pressure-bearing disc 602, the data screen 605 is electrically connected to the outside of the photomultiplier tube 603 and the light interaction module 604, the light interaction module 604 comprises a light detector, an electric signal amplifier, a light receiver and a controller, the light detector is used for detecting photons generated by a chemical reaction, the electric signal amplifier converts a light signal into an electric signal, and the controller feeds back the electric signal to the data screen 605 for observation.

[0025] When working, the containers corresponding to the added solvents are sequentially placed on the balance plate 5 in the accommodating holes 501 to form multiple comparative experiments, the dropping tubes 4 corresponding to the reaction solvents are sequentially inserted through the limiting holes 306 in the multi-hole mounting column 305, the cylinder 308 drives the push rod 307 to drive the mobile box 301 to linearly slide along the frame sleeve 1, so that the dropping tube 4 reaches the corresponding container and stops, the dropping solution is performed, the high-speed camera 309 synchronously observes the dropping condition and feeds back to the display screen 310, then the light interaction module 604 and the photomultiplier tube 603 start to work, the light detector, the electric signal amplifier, the light receiver and the controller, the light detector is used for detecting photons generated by a chemical reaction, the electric signal amplifier converts a light signal into an electric signal, and the controller feeds back the electric signal to the data screen 605 for observation.

[0026] Through the above steps, the movable reagent module 3 is linearly arranged in the middle of the frame sleeve 1 and can carry the dropping tube 4 to perform dropping test reagents, the balance plate 5 is correspondingly arranged below the frame sleeve 1, the movable reagent module 3 is arranged to carry the dropping reaction container to be stable, the chemiluminescence detection assembly 6 is linearly arranged on the balance plate 5 and can be used for chemiluminescence detection, thereby improving the overall chemiluminescence detection effect.

[0027] The embodiments of the utility model are described in detail in combination with the drawings above, but the utility model is not limited to the above-mentioned embodiments, and various changes can be made within the knowledge range possessed by the person skilled in the art without departing from the purpose of the utility model.

Claims

1. A chemiluminescence detection apparatus with reagent moving mechanism, comprising a frame cover (1); characterized in that: It also includes support column (2), movable reagent module (3), drop tube (4), balance plate (5) and chemiluminescence detection assembly (6); for bearing movable reagent module (3) stable sliding and keep chemiluminescence detection frame cover (1) loaded, the middle part of frame cover (1) is provided with movable reagent module (3) which can linearly slide to load drop tube (4) for drop test reagent, the middle part of movable reagent module (3) is provided with drop tube (4) for containing drop liquid test, the lower part of frame cover (1) is provided with balance plate (5) for loading drop reaction container stably, balance plate (5) is linearly provided with chemiluminescence detection assembly (6) for chemiluminescence detection, balance plate (5) and frame cover (1) are provided with support column (2) for supporting stably at the corner.

2. The chemiluminescence detection apparatus with a reagent moving mechanism according to claim 1, characterized in that: Frame cover (1) includes U-shaped frame (101), fixed plate (102), slide rail (103), positioning hole (104), guide hole (105), protection plate (106), dismounting plate (107), positioning sleeve (108), positioning bolt (109) and connecting pin (110), the two groups of U-shaped frames (101) are linearly arranged, the four corners of the two groups of U-shaped frames (101) are provided with positioning holes (104) for inserting the support column (2), the two sides of the two groups of U-shaped frames (101) are provided with slide rails (103) for sliding the movable reagent module (3).

3. The chemiluminescence detection apparatus with a reagent moving mechanism according to claim 2, characterized in that: One end of the two groups of U-shaped frames (101) is fixedly connected with the protection plate (106), the center of the protection plate (106) is provided with the guide hole (105), one end of the two groups of U-shaped frames (101) away from the protection plate (106) is provided with the dismounting plate (107), the dismounting plate (107) is symmetrically provided with the positioning sleeve (108), the connecting pin (110) is arranged between the positioning sleeve (108) and the dismounting plate (107), and the positioning bolt (109) is sleeved on the connecting pin (110).

4. The chemiluminescence detection apparatus with a reagent moving mechanism according to claim 1, characterized in that: The support column (2) is linearly provided with three groups of loose bolts (201) for positioning and longitudinal height adjustment of the frame cover (1), and the bottom of the support column (2) is provided with a damping base (202).

5. The chemiluminescence detection apparatus with a reagent moving mechanism according to claim 1, characterized in that: Movable reagent module (3) includes moving box (301), center hole (302), sliding table (303), connecting hole (304), multi-hole mounting column (305), limiting hole (306), push rod (307), air cylinder (308), high-speed camera (309) and display screen (310), both sides of the moving box (301) are provided with sliding tables (303), the rear end of the moving box (301) is provided with a push rod (307), the air cylinder (308) drives the push rod (307) to drive the moving box (301) to slide linearly on the frame cover (1).

6. The chemiluminescence detection apparatus with a reagent moving mechanism according to claim 1, characterized in that: The high-speed camera (309) is arranged on the two sides of the bottom of the moving box (301) and connected with the slide table (303), the outer end of the high-speed camera (309) is provided with a display screen (310), the center of the moving box (301) is provided with a center hole (302), a connecting hole (304) is arranged on the outer periphery of the center hole (302) in a ring shape, a multi-hole mounting column (305) is arranged in the center hole (302), and a limiting hole (306) is arranged in the multi-hole mounting column (305) in a ring shape.

7. The chemiluminescence detection apparatus with a reagent moving mechanism according to claim 1, characterized in that: The balance plate (5) is linearly provided with a containing chemical luminescence detection component (6) placing hole (501), the chemical luminescence detection component (6) comprises a shock absorbing sleeve (601), a pressure bearing disc (602), a photomultiplier (603), a light interaction module (604) and a data screen (605), the shock absorbing sleeve (601) is arranged on the outer side of the pressure bearing disc (602), the photomultiplier (603) and the light interaction module (604) are arranged on the pressure bearing disc (602) in a ring shape, the data screen (605) is electrically connected to the outer part of the photomultiplier (603) and the light interaction module (604), and the light interaction module (604) comprises a light detector, an electric signal amplifier, a light receiver and a controller which are electrically connected.

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