Stem cell low-temperature preservation box

Abstract

The utility model relates to the technical field of medical instruments, in particular to a stem cell low-temperature preservation box. Comprising a storage box, a sealing mechanism and a plurality of placing pipes; a partition plate is horizontally arranged on the inner side of the storage box, and the space partitioned by the bottom end of the partition plate is a cooling cavity. The plurality of placing pipes are vertically arranged on the inner side of the storage box, and a plurality of cold air inlet holes are formed in the placing pipes; a movable seat is arranged on the inner side of the placing pipe, and a first elastic assembly is connected between the movable seat and the placing pipe; the sealing mechanism comprises a cover plate and a plurality of sealing covers; the multiple sealing covers and the multiple containing pipes are arranged in a one-to-one correspondence mode, and the upper ends of the sealing covers are rotationally connected with linear rotating blocks. According to the technical scheme, after a test tube is taken out and the test tube is not completely moved into the inner side of the placing tube, the movable seat can automatically seal the cold air inlet hole, and leakage of a large amount of cold air is avoided.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, and in particular to a stem cell cryopreservation box. Background Technology

[0002] Stem cells are a type of pluripotent cell with self-renewal capacity. Under certain conditions, they can differentiate into various functional cells. Based on their developmental stage, stem cells are classified into embryonic stem cells and adult stem cells. Based on their developmental potential, they are further classified into three categories: totipotent stem cells, multipotent stem cells, and unipotent stem cells. Stem cells are undifferentiated, immature cells with the potential to regenerate various tissues, organs, and the human body; they are known in the medical field as "universal cells." Currently, the preservation of stem cells requires placing them inside test tubes, which are then placed in a low-temperature incubator for storage.

[0003] Multiple test tubes are usually stored in the stem cell preservation box. When a single test tube is taken out, the box needs to be opened, which can easily cause a large amount of cold air to leak out. Utility Model Content

[0004] The purpose of this invention is to address the problems existing in the background technology by proposing a stem cell cryopreservation box.

[0005] The technical solution of this utility model is a stem cell cryopreservation box, comprising:

[0006] The storage box has an opening at the top and a horizontal partition on the inside. The space between the bottom of the partition is a cooling cavity. A cooler is installed on the storage box to cool the inside of the cooling cavity.

[0007] Multiple placement tubes are vertically installed inside the storage box and penetrate through the partition. Multiple cold air inlets are provided on the placement tubes. A movable seat is provided inside the placement tube, and a first elastic component is connected between the movable seat and the placement tube. A limit tube is provided on the upper part of the inner side of the placement tube.

[0008] The sealing mechanism includes a cover plate and multiple sealing covers. The cover plate is located at the top of the opening of the storage box and has a detachable connection with the storage box. Multiple sealing covers are correspondingly arranged with multiple placement tubes. A rotating block is rotatably connected to the top of the sealing cover. Multiple first circular holes are provided on the cover plate for the multiple sealing covers to pass through. An annular groove is provided around the periphery of the first circular hole, and insertion holes are provided on both sides of the top of the first circular hole.

[0009] Preferably, both ends of the bottom of the cover plate are connected to insert rods, and the bottom ends of the insert rods are provided with wedge-shaped blocks; both ends of the storage box are provided with movable locking blocks that movably penetrate their side walls, and the movable locking blocks are provided with rectangular holes; a second elastic component is connected between the movable locking blocks and the storage box, the second elastic component includes a second guide rod, a second spring and a second limiting block, wherein a connecting slider is connected to the movable locking block, the second guide rod is connected to the inner wall of the storage box, the connecting slider is slidably disposed on the second guide rod, the second limiting block is disposed at the end of the second guide rod, and the second spring is sleeved and installed on the second guide rod.

[0010] Preferably, a push rod is vertically connected to the sealing cover.

[0011] Preferably, the upper end of the limiting tube is provided with a funnel, and the funnel has a through hole for inserting a push rod, and the bottom end of the push rod is pointed.

[0012] Preferably, the first elastic component includes a first guide rod, a first spring, and a first limiting block, wherein the first guide rod is vertically disposed inside the placement tube, the movable seat is slidably disposed on the first guide rod, the first limiting block is disposed at the end of the first guide rod, and the first spring is sleeved and installed at the bottom of the first guide rod.

[0013] Preferably, the storage box, partitions, and placement tubes are all coated with heat-insulating paint.

[0014] Compared with the prior art, the present invention has the following beneficial technical effects:

[0015] 1. After the test tube is removed and before it is completely moved into the inner side of the placement tube, the movable seat can automatically seal the cold air inlet to prevent a large amount of cold air leakage.

[0016] 2. The cover plate allows for the simultaneous removal of multiple sealing caps, thereby improving the efficiency of placing multiple test tubes. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the structure of this utility model.

[0018] Figure 2 This is an exploded view of the present invention.

[0019] Figure 3 This is a cross-sectional view of the placement tube in this utility model.

[0020] Figure 4 for Figure 2 A magnified schematic diagram of the structure at point A.

[0021] Reference numerals: 1. Storage box; 2. Refrigerator; 3. Handle; 4. Cover plate; 401. First circular hole; 402. Annular groove; 403. Insertion hole; 5. Placement tube; 501. Cold air inlet; 6. Partition plate; 7. Sealing cover; 8. Slotted rotating block; 9. Push rod; 10. Limiting tube; 11. Funnel; 111. Perforation; 12. Movable seat; 13. Sealing film; 14. Sponge; 151. First guide rod; 152. First spring; 153. First limiting block; 16. Movable locking block; 161. Rectangular hole; 17. Connecting slider; 181. Second guide rod; 182. Second spring; 183. Second limiting block; 19. Insertion rod; 20. Wedge block. Detailed Implementation

[0022] Example 1

[0023] like Figures 1-3 As shown in the figure, the stem cell cryopreservation box proposed in this embodiment includes a storage box 1, a sealing mechanism, and multiple placement tubes 5.

[0024] The upper end of the storage box 1 is open, and a partition 6 is horizontally arranged inside the storage box 1. The space separated by the bottom end of the partition 6 is a cooling cavity. A cooler 2 for cooling the inside of the cooling cavity is installed on the storage box 1. The cooler 2 can be a single-plate cooler. Furthermore, in order to facilitate carrying the storage box 1, a handle 3 is installed on the storage box 1.

[0025] Multiple placement tubes 5 are vertically arranged inside the storage box 1, and the placement tubes 5 penetrate the partition 6. The storage box 1, partition 6, and placement tubes 5 are all coated with heat-insulating paint. Multiple cold air inlets 501 are provided on the placement tubes 5. A movable seat 12 is provided inside the placement tube 5. It should be noted that, to improve the sealing between the movable seat 12 and the inner wall of the placement tube 5, multiple sealing films 12 are provided around the movable seat. For convenient placement of test tubes, a test tube placement groove is provided on the movable seat 12, and a sponge 14 is placed inside the test tube placement groove. The sponge acts as a cushioning agent. A first elastic component is connected between the movable seat 12 and the placement tube 5. The first elastic component includes a first guide rod 151, a first spring 152, and a first limiting block 153. The first guide rod 151 is vertically arranged inside the placement tube 5, the movable seat 12 is slidably arranged on the first guide rod 151, the first limiting block 153 is arranged at the end of the first guide rod 151, and the first spring 152 is sleeved and installed at the bottom of the first guide rod 151. The first elastic component is used to realize the rapid upward reset of the movable seat 12. A limiting tube 10 is provided on the upper inner side of the placement tube 5.

[0026] The sealing mechanism includes a cover plate 4 and multiple sealing covers 7; the cover plate 4 is located at the upper end of the opening of the storage box 1, and the cover plate 4 and the storage box 1 have a detachable connection structure; multiple sealing covers 7 are arranged one-to-one with multiple placement tubes 5, and a straight rotating block 8 is rotatably connected to the upper end of the sealing cover 7. Multiple first circular holes 401 are opened on the cover plate 4 for multiple sealing covers 7 to pass through. An annular groove 402 is provided on the periphery of the first circular hole 401, and insertion holes 403 are provided on both sides of the upper end of the first circular hole 401.

[0027] A push rod 9 is vertically connected to the sealing cap 7. When sealing the upper end of the placement tube 5, the push rod 9 is inserted into the inside of the placement tube 5. The bottom end of the push rod 9 presses against the movable seat 12 to move, so that the sealing cap 7 does not need to press the test tube to move and thus drive the movable seat 12 to move, avoiding damage to the test tube.

[0028] The upper end of the limiting tube 10 is provided with a funnel 11, and the funnel 11 is provided with a through hole 111 for the push rod 9 to be inserted. The bottom end of the push rod 9 is pointed, which makes it easy for the push rod 9 to be inserted into the inside of the through hole 111.

[0029] Specifically, when placing the test tube containing the stem cells, first rotate the push rod 9 so that its two ends are aligned with the corresponding two insertion holes 403. Then, move the sealing cap 7 out from the inside of the first circular hole 401, separating the sealing cap 7 from the placement tube 5. To improve the sealing between the sealing cap 7 and the placement tube 5, a sealing gasket can be placed at the bottom of the sealing cap 7. Then, insert the test tube into the inside of the limiting tube 10, so that the bottom of the test tube contacts the movable seat 12. The limiting tube 10 is used to limit the test tube. In this state, the movable seat 12 covers the multiple cold air inlets 501, so that the cold air in the cooling cavity will not flow out through the cold air inlets 501. Then, align the sealing cap 7 with the first circular hole 401, so that the sealing cap 7 presses on the upper end of the test tube, and push... The test tube gradually moves downwards. When both ends of the rotating block 8 are inserted into the designated positions in the insertion holes 403 on both sides, the rotating block 8 is driven to rotate so that both ends are engaged inside the annular groove 402, thereby limiting the sealing cover 7. At this time, the sealing cover 7 covers the upper opening of the placement tube 5. After the test tube moves downwards to the designated position, the movable seat 12 moves downwards to the designated position. At this time, multiple cold air inlets 501 are exposed, allowing cold air to enter the inside of the placement tube 5 to cool the test tube. It should be added that after the cover plate 4 is disassembled from the storage box 1, lifting the cover plate 4 can drive multiple sealing covers 7 to move synchronously, thus eliminating the need to disassemble multiple sealing covers 7 one by one, which facilitates the simultaneous placement of multiple test tubes.

[0030] Example 2

[0031] like Figure 2 and Figure 4 As shown, in this embodiment of the stem cell cryopreservation box, compared to Embodiment 1, both ends of the bottom of the cover plate 4 are connected to insertion rods 19, and the bottom ends of the insertion rods 19 are provided with wedge-shaped blocks 20; both ends of the storage box 1 are provided with movable locking blocks 16 that movably penetrate their side walls, and the movable locking blocks 16 have rectangular holes 161; a second elastic component is connected between the movable locking blocks 16 and the storage box 1, the second elastic component including a second guide rod 181, a second spring 182 and a second limiting block 183, wherein the movable locking blocks 16 are connected to a connecting slider 17, and the second guide rod 181 is connected to the inner wall of the storage box 1, connecting... The slider 17 is slidably mounted on the second guide rod 181, the second limiting block 183 is mounted on the end of the second guide rod 181, and the second spring 182 is sleeved on the second guide rod 181. When the cover plate 4 is fixedly connected to the storage box 1, the cover plate 4 is aligned with the upper end of the storage box 1, so that the wedge block 20 is inserted into the inner side of the rectangular hole 161. The inclined surface of the wedge block 20 presses the movable locking block 16 to move. When the wedge block 20 moves to the position below the movable locking block 16, the movable locking block 16 is driven to reset under the elastic force of the second spring 182, so as to realize the locking and limiting of the wedge block 20. Its fixing structure is simple and easy to operate.

[0032] The embodiments of the present invention have been described in detail above with reference to the accompanying drawings. However, the present invention is not limited thereto. Various changes can be made within the scope of knowledge possessed by those skilled in the art without departing from the spirit of the present invention.

Claims

1. A stem cell cryopreservation box, characterized in that, include: Storage box (1), the upper end of storage box (1) is open, and a partition (6) is horizontally arranged inside storage box (1). The space separated by the bottom end of partition (6) is a cooling cavity; a cooler (2) for cooling the inside of the cooling cavity is installed on storage box (1). Multiple placement tubes (5) are vertically arranged inside the storage box (1), and the placement tubes (5) penetrate the partition (6). Multiple cold air inlets (501) are provided on the placement tubes (5). A movable seat (12) is provided inside the placement tubes (5), and a first elastic component is connected between the movable seat (12) and the placement tubes (5). A limit tube (10) is provided on the upper part of the inner side of the placement tubes (5). The sealing mechanism includes a cover plate (4) and multiple sealing covers (7); the cover plate (4) is set at the upper end of the opening of the storage box (1), and the cover plate (4) and the storage box (1) have a detachable connection structure; multiple sealing covers (7) are set one-to-one with multiple placement tubes (5), and a straight rotating block (8) is rotatably connected to the upper end of the sealing cover (7). Multiple first circular holes (401) are opened on the cover plate (4) for multiple sealing covers (7) to pass through respectively. An annular groove (402) is provided on the periphery of the first circular hole (401), and insertion holes (403) are provided on both sides of the upper end of the first circular hole (401).

2. The stem cell cryopreservation box according to claim 1, characterized in that, Both ends of the bottom of the cover plate (4) are connected to insert rods (19), and the bottom end of the insert rods (19) is provided with wedge blocks (20); both ends of the storage box (1) are provided with movable locking blocks (16) that can move through its side wall, and the movable locking blocks (16) are provided with rectangular holes (161); a second elastic component is connected between the movable locking blocks (16) and the storage box (1), the second elastic component includes a second guide rod (181), a second spring (182) and a second limiting block (183), wherein the movable locking block (16) is connected to a connecting slider (17), the second guide rod (181) is connected to the inner wall of the storage box (1), the connecting slider (17) is slidably disposed on the second guide rod (181), the second limiting block (183) is disposed at the end of the second guide rod (181), and the second spring (182) is sleeved and installed on the second guide rod (181).

3. The stem cell cryopreservation box according to claim 1, characterized in that, A push rod (9) is vertically connected to the sealing cap (7).

4. A stem cell cryopreservation box according to claim 3, characterized in that, The upper end of the limiting tube (10) is provided with a funnel (11), and the funnel (11) is provided with a through hole (111) for inserting the push rod (9). The bottom end of the push rod (9) is pointed.

5. A stem cell cryopreservation box according to claim 1, characterized in that, The first elastic component includes a first guide rod (151), a first spring (152), and a first limiting block (153). The first guide rod (151) is vertically disposed inside the placement tube (5), the movable seat (12) is slidably disposed on the first guide rod (151), the first limiting block (153) is disposed at the end of the first guide rod (151), and the first spring (152) is sleeved and installed at the bottom of the first guide rod (151).

6. A stem cell cryopreservation box according to claim 1, characterized in that, The storage box (1), the partition (6) and the placement tube (5) are all coated with heat-insulating paint.

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