Timed and quantitative implantable drug sustained-release device
By designing controlled-release orifices and controlled-release rods on sustained-release drugs, the problems of low drug content and high cost have been solved, enabling timed and quantitative release of drugs and long-term sustained release, reducing costs and improving release efficiency.
Patent Information
- Application Number
- CN202422630435.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-30
- Publication Date
- 2025-11-21
- Estimated Expiration
- 2034-10-30
AI Technical Summary
Existing drug sustained-release devices suffer from low drug content and high cost.
A timed and quantitative implantable drug release device was designed. By creating a control-release hole in the drug and equipping it with a control-release rod and an implant block, the device utilizes the structural design of a connecting piece and an anti-detachment block to achieve timed and quantitative drug release. Combined with the support of an isolation layer and an airbag, the device ensures the slow release of the drug within the body.
This achieves efficient drug delivery and long-term release, reduces manufacturing costs, and ensures the accuracy and safety of the release effect.
Smart Images
Figure CN223569834U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The application relates to the technical field of drug slow release, and particularly relates to a timing and quantitative implantable drug slow release device. BACKGROUND
[0002] The drug slow release device is a novel drug delivery device for human disease treatment, which is designed and used to realize slow release of drugs, directly acts on the affected part, so that the optimal treatment effect is achieved, and the toxic and side effects of directly taking drugs on human organs are reduced. The drug slow release device is designed by specific materials and structures, so that the drugs can be slowly released in the biological body according to a predetermined speed. The release mode can prolong the action time of the drugs, reduce the frequency of drug delivery, and maintain a stable blood drug concentration, so that the peak-valley phenomenon is avoided or reduced, and the treatment effect is improved.
[0003] The existing drug slow release device is mainly coated with slow release drugs on a biological stent, and then the stent is implanted into the human body, and the drug slow release is waited to complete the drug delivery. The mode has the problems of low drug content and high cost.
[0004] Therefore, the application provides a timing and quantitative implantable drug slow release device to solve the above problems. CONTENT OF THE UTILITY MODEL
[0005] The application provides a timing and quantitative implantable drug slow release device, which aims to solve the problems of low drug content and high cost of the existing drug slow release device in the background art.
[0006] To achieve the above object, the application provides the following technical scheme: a timing and quantitative implantable drug slow release device, comprising a slow release drug and an implanting mechanism sleeved on the slow release drug.
[0007] The slow release drug is provided with a control release hole;
[0008] The implanting mechanism comprises an implanting block, a clamping groove matched with the slow-release medicine is formed in the implanting block, a control-release rod matched with the control-release hole and having a length smaller than the depth of the control-release hole is fixedly installed in the clamping groove, the control-release rod is inserted into the control-release hole, three circumferential distribution accommodating grooves are formed on the outer side wall of the implanting block, a connecting piece is fixedly installed in the accommodating groove, and an anti-falling block matched with the outer side wall of the slow-release medicine is fixedly installed on the end of the connecting piece away from the accommodating groove.
[0009] Preferably, in order to make the slow-release medicine better contact with the internal environment, a spring piece is fixedly installed in the clamping groove, and the end of the spring piece away from the inner side wall of the implanting block is arranged in abutment with the top of the slow-release medicine. The release effect is ensured.
[0010] Preferably, in order to release the medicine in a timed and quantitative manner, the slow-release medicine comprises a plurality of medicine slow-release layers and non-medicine slow-release layers, the plurality of medicine slow-release layers and non-medicine slow-release layers are arranged in an interlaced manner, and the outer side walls of the medicine slow-release layers and non-medicine slow-release layers are coated with an isolation layer. The slow-release medicine can release the medicine in a layered and gradual manner.
[0011] Preferably, in order to reduce the release speed, the distance difference between the control-release hole and the control-release rod is smaller than the thickness of a single medicine slow-release layer or non-medicine slow-release layer. The medicine release quality is further improved.
[0012] Preferably, in order to support the implanting block, a plurality of air bags are fixedly installed on the outer side wall of the implanting block in a circumferential uniform manner. The installation and removal are facilitated, and the safety and reliability are improved.
[0013] The drug slow release device, the anti-loose block is moved outward, the connecting pieces are bent in the accommodation groove, the distance between the three connecting pieces is expanded, the opening distance between the three anti-loose blocks is increased, the slow release drug is placed in the clamping groove on the implant block, the three connecting pieces are loosened, the three anti-loose blocks are automatically reset, the bottom of the slow release drug is fixed, the control release rod is inserted into the control release hole, then the implant block is implanted into the lesion position of the organism, the slow release drug is slowly released to treat the drug through the control release hole, the slow release drug is gradually thinned along with the gradual release of the drug, the gravity gradually drops along the control release rod, and the drug is gradually released. Compared with the existing method of coating a drug coating on the stent, more drugs can be carried, the duration is longer, the structure is simple, and the cost is low.
[0014] The thickness of the drug slow release layer controls the drug release time, the thickness of the non-drug slow release layer controls the drug interval release time, so that the slow release drug can be released in time and quantity, the drug is more accurate, the slow release drug is coated with a separation layer, only the bottom of the slow release drug is in contact with the environment in the body through the control release hole, and the slow release drug can be released in layers. BRIEF DESCRIPTION OF DRAWINGS
[0015] Fig. 1 It is an appearance structure diagram of a timing and quantity implantable drug slow release device.
[0016] Fig. 2 It is a bottom structure diagram of a timing and quantity implantable drug slow release device.
[0017] Fig. 3 It is a cross-sectional structure diagram of a timing and quantity implantable drug slow release device.
[0018] In the figure:
[0019] 1, slow release drug; 11, drug slow release layer; 12, non-drug slow release layer; 13, control release hole; 14, separation layer; 2, implant mechanism; 21, implant block; 22, clamping groove; 23, control release rod; 24, spring piece; 25, accommodation groove; 26, connecting piece; 27, anti-loose block; 28, air bag. DETAILED DESCRIPTION
[0020] The technical solutions in the embodiments of the present application will be described clearly and completely below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor are within the scope of protection of the present application.
[0021] Embodiment 1
[0022] The embodiment provides a timing and quantitative implantable drug slow-release device, which comprises a slow-release drug 1 and an implanting mechanism 2 sleeved on the slow-release drug 1. Figs. 1-3
[0023] The slow-release drug 1 is provided with a control-release hole 13.
[0024] The implanting mechanism 2 comprises an implanting block 21, the implanting block 21 is provided with a clamping groove 22 matched with the slow-release drug 1, the clamping groove 22 is fixedly provided with a control-release rod 23 matched with the control-release hole 13 and having a length smaller than the depth of the control-release hole 13, the control-release rod 23 is inserted into the control-release hole 13, the outer side wall of the implanting block 21 is provided with three circumferentially distributed accommodation grooves 25, the accommodation grooves 25 are fixedly provided with connecting plates 26, and the connecting plates 26 are fixedly provided with anti-disengagement blocks 27 matched with the outer side wall of the slow-release drug 1 at the ends away from the accommodation grooves 25.
[0025] In use, the anti-disengagement blocks 27 are moved outward, the connecting plates 26 are bent in the accommodation grooves 25, the distance between the three connecting plates 26 is expanded, the opening distance between the three anti-disengagement blocks 27 is increased, the slow-release drug 1 is placed into the clamping groove 22 on the implanting block 21, the three connecting plates 26 are loosened, the three anti-disengagement blocks 27 are automatically reset, the bottom of the slow-release drug 1 is fixed, the control-release rod 23 is inserted into the control-release hole 13, then the implanting block 21 is implanted into the lesion position of the organism, the slow-release drug 1 slowly releases the therapeutic drug through the control-release hole 13, the slow-release drug 1 is gradually thinned along with the gradual release of the drug, the slow-release drug 1 is gradually released along with the gravity gradually descending along the control-release rod 23, compared with the existing drug coating layer on the stent, more drugs can be carried, the duration is longer, the structure is simple, and the cost is low.
[0026] Specifically, the clamping groove 22 is fixedly provided with an elastic sheet 24, and the end of the elastic sheet 24 away from the inner side wall of the implanting block 21 is arranged in abutment with the top of the slow-release drug 1. In use, when the slow-release drug 1 is gradually thinned, the elastic sheet 24 is gradually released, and the slow-release drug 1 is automatically pushed downward, so that the bottom of the slow-release drug 1 and the control-release hole 13 can always contact the environment in the organism, and the release effect is ensured.
[0027] More specifically, the sustained-release medicine 1 comprises several layers of drug sustained-release layers 11 and non-drug sustained-release layers 12, the layers of drug sustained-release layers 11 and non-drug sustained-release layers 12 are arranged alternately, and the outer wall of the drug sustained-release layers 11 and the non-drug sustained-release layers 12 is coated with an isolation layer 14. In use, the thickness of the drug sustained-release layers 11 controls the drug release time, and the thickness of the non-drug sustained-release layers 12 controls the drug interval release time, so that the sustained-release medicine 1 can release the drug in time and quantity, and the drug administration is more accurate. The outer layer of the sustained-release medicine 1 is coated with an isolation layer 14, which ensures that only the bottom of the sustained-release medicine 1 can be in direct contact with the body environment in the controlled-release hole 13, and ensures that the sustained-release medicine 1 can release the drug gradually in layers.
[0028] Further, the distance difference between the controlled-release hole 13 and the controlled-release rod 23 is less than the thickness of a single layer of drug sustained-release layers 11 or non-drug sustained-release layers 12. In use, when the sustained-release medicine 1 releases the drug, the small distance difference ensures that the controlled-release hole 13 does not release too much at one time when it contacts the human body environment, thereby reducing the drug release speed and further improving the drug release quality.
[0029] Further, the implant block 21 is fixedly installed with several air bags 28 arranged uniformly in a circumferential direction on the outer wall. In use, after the implant block 21 is implanted in the body, the air bags 28 support the implant block 21, and facilitate positioning by affecting the equipment, convenient installation and removal, and are more safe and reliable.
[0030] The above is only the preferred specific embodiment of the present application, but the protection scope of the present application is not limited thereto. Any person skilled in the art can make equivalent replacements or changes to the technical solution and concept of the present application within the technical scope disclosed by the present application, which should be covered within the protection scope of the present application.
Claims
1. A timed and metered implantable drug release device, comprising a sustained-release drug (1) and an implantation mechanism (2) fitted onto the sustained-release drug (1), characterized in that: The sustained-release drug (1) is provided with a controlled-release hole (13); The implantation mechanism (2) includes an implantation block (21), which has a slot (22) adapted to the sustained-release drug (1) and a control-release rod (23) adapted to the control-release hole (13) and whose length is less than the depth of the control-release hole (13) is fixedly installed in the slot (22). The control-release rod (23) is inserted into the control-release hole (13). The outer wall of the implantation block (21) has three circumferentially distributed relief grooves (25). A connecting piece (26) is fixedly installed in the relief groove (25). An anti-dislodgement block (27) adapted to the outer wall of the sustained-release drug (1) is fixedly installed on one end of the connecting piece (26) away from the relief groove (25).
2. The timed and quantitative implantable drug release device according to claim 1, characterized in that: A spring clip (24) is fixedly installed in the slot (22), and one end of the spring clip (24) away from the inner wall of the implant block (21) is set against the top of the sustained-release drug (1).
3. The timed and quantitative implantable drug release device according to claim 1, characterized in that: The sustained-release drug (1) includes several drug sustained-release layers (11) and non-drug sustained-release layers (12), which are arranged alternately. An isolation layer (14) is coated on the outer wall of the drug sustained-release layers (11) and non-drug sustained-release layers (12).
4. The timed and quantitative implantable drug release device according to claim 3, characterized in that: The distance difference between the controlled-release orifice (13) and the controlled-release rod (23) is less than the thickness of the single-layer drug sustained-release layer (11) or the non-drug sustained-release layer (12).
5. The timed and quantitative implantable drug release device according to claim 1, characterized in that: Several airbags (28) are fixedly installed on the outer wall of the implant block (21) in a circumferentially uniform manner.