Cell separation device with cell sample protection function

Abstract

The utility model discloses a cell separation device with a function of protecting cell samples, which relates to the technical field of cell separation, and comprises a handle, the bottom of the handle is fixedly connected with a cover plate component, the outer surface of the bottom of the cover plate component is in threaded connection with a separation component, the front surface of the separation component is provided with a controller, and the controller is in threaded connection with the separation component. The separation assembly comprises a separation box, a driving motor is fixedly mounted in the middle of the bottom of a groove in the top of the separation box, the output end of the driving motor is fixedly connected with a centrifugal placement assembly, and a plurality of test tube assemblies are arranged at the bottom of the inner wall of the centrifugal placement assembly. According to the cell separation device with the cell sample protection function, the rubber layer connected with the inner cavity of the placing hole is used for extruding and clamping the test tube assembly, and the cover plate assembly is in threaded connection with the inner wall of the top of the placing box, so that the bottom of the cover plate is propped against the test tube assembly, and the test tube assembly is fixed; the test tube assembly is prevented from shaking during separation, so that the cell separation effect is not influenced.

Description

TECHNICAL FIELD

[0001] The utility model relates to cell separation technical field, especially a cell separation device with cell sample protection function. BACKGROUND

[0002] Cell separation technology includes centrifugal technology, flow cytometry and cell electrophoresis, centrifugal is the basic means to study such as cell nucleus, mitochondrion, golgi body, lysosome and microbody, and various macromolecules, flow cytometry is a technology for rapid quantitative analysis and sorting of single cells, cell electrophoresis refers to that cells have net positive or negative charge on the surface under a certain value, and can move under the action of an external electric field, but the cell separation device currently used usually cannot better protect the cell sample during use, and the cell sample is prone to damage due to collision during use, affecting the subsequent use of the device, thereby reducing the use effect of the device.

[0003] For example, the patent with the announcement number CN215560187U discloses a cell separation device with cell sample protection function, which comprises a shell, a fixing mechanism, a mounting mechanism, a second clamping groove, a second threaded shaft and a sliding rail, the shell is provided with a protection mechanism on one side, the fixing mechanism is installed on one side of the shell, the mounting mechanism is installed on one side of the shell, the second clamping groove is formed in one side of the shell, and a second clamping block is installed on one side of the second clamping groove, and a handle is welded on one side of the second clamping block. The cell separation device with cell sample protection function can protect the cell sample conveniently through the setting of the lifting sleeve, the lifting frame, the first threaded shaft and the protective cover. The lifting sleeve and the lifting frame can adjust the height according to the size of the cell sample, and the first threaded shaft and the protective cover can protect the cell sample more conveniently, prevent the cell sample from being damaged due to collision, and affect the subsequent use.

[0004] The existing cell separation device with cell sample protection function has the following problems:

[0005] The separation efficiency and storage of the existing cell separation device with cell sample protection function are not good, and the centrifugal test tube is prone to shaking during separation, which affects the quality of cell separation. UTILITY MODEL CONTENT

[0006] The utility model provides a cell separation device with cell sample protection function to solve the problems in the background art.

[0007] To solve the above technical problems, the utility model adopts the following technical scheme:

[0008] A cell separation device with cell sample protection function, comprising a hand handle, the bottom of the hand handle is fixedly connected with a cover plate assembly, the bottom outer surface of the cover plate assembly is threadedly connected with a separation assembly, and the front surface of the separation assembly is provided with a controller;

[0009] The separation assembly comprises a separation box, a driving motor is fixedly installed in the middle of the groove bottom of the top of the separation box, the output end of the driving motor is fixedly connected with a centrifugal placement assembly, and the inner wall bottom of the centrifugal placement assembly is provided with a plurality of test tube assemblies;

[0010] The centrifugal placement assembly comprises a placement box, screw grooves are formed in the inner wall near the top of the placement box, a sealing rubber layer is fixedly connected to the top of the placement box around the four corners, and a cold and hot cycle mechanism is fixedly installed in the middle of the inner wall bottom of the placement box.

[0011] Preferably, the front surface of the separation box is fixedly installed with the outer surface of the controller, and the inner wall top of the centrifugal placement assembly is threadedly connected with the bottom of the cover plate assembly around the four corners.

[0012] Preferably, a plurality of placement holes are formed in the inner wall bottom of the placement box, a rubber layer is fixedly connected to the inner wall around the four corners of the plurality of placement holes, and the outer surface of the rubber layer is overlapped with the outer surface of the test tube assembly.

[0013] Preferably, the inner wall of the screw groove is threadedly connected with the bottom of the cover plate assembly around the four corners, and the bottom of the placement box is fixedly connected with the output end of the driving motor.

[0014] Preferably, the plurality of test tube assemblies comprise a plurality of centrifugal test tubes, the outer surface of the plurality of centrifugal test tubes is overlapped with the inner wall of the plurality of placement holes, a sealing cover is inserted into the inner wall of the top of the plurality of centrifugal test tubes, and the outer surface of the sealing cover is provided with friction lines.

[0015] Preferably, the cover plate assembly comprises a cover plate, the top of the cover plate is fixedly connected with the bottom of the hand handle, screw blocks are formed in the bottom of the cover plate around the four corners, and the outer surface of the screw blocks is threadedly connected with the inner wall of the screw groove.

[0016] Preferably, the bottom of the cover plate is fixedly connected with a pressing block, and the bottom of the pressing block is overlapped with the top of the sealing rubber layer.

[0017] Thanks to the above technical scheme, the present application has the following technical progress compared with the prior art:

[0018] 1. The cell separation device with cell sample protection function drives the placement box through the driving motor, facilitates the separation of cells of the plurality of test tube assemblies, improves the storage of multiple cell separation, and improves the working efficiency.

[0019] 2. The utility model provides a cell separation device with cell sample function is protected, through the rubber layer of placement hole inner chamber connection plays extruding clamping test tube subassembly, and the cover plate subassembly screw thread connection placement box top inner wall, make its cover plate's bottom resist test tube subassembly, realize fixed test tube subassembly, prevented the shaking of test tube subassembly when separating, influence cell separation's effect. BRIEF DESCRIPTION OF DRAWINGS

[0020] Figure 1 It is the structural schematic diagram of the utility model;

[0021] Figure 2 It is the structural schematic diagram of the separation subassembly of the utility model;

[0022] Figure 3 It is the structural schematic diagram of the utility model's Figure 2 It is the enlarged structural schematic diagram of A place in the middle;

[0023] Figure 4 It is the enlarged structural schematic diagram of the centrifugal placement subassembly of the utility model;

[0024] Figure 5 It is the structural schematic diagram of the cover plate subassembly of the utility model.

[0025] In the drawing: 1, separation subassembly;11, separation box;12, drive motor;13, centrifugal placement subassembly;131, placement box;132, thread groove;133, placement hole;134, rubber layer;135, cold and hot cycle mechanism;136, sealing rubber layer;14, test tube subassembly;141, centrifugal test tube;142, sealing cover;143, frictional grain;2, controller;3, cover plate subassembly;31, cover plate;32, threaded block;33, pressing block;4, hand carrying handle. DETAILED DESCRIPTION

[0026] In order to make the technical means, creation features, achieve purposes and effects of the utility model easy to understand, the utility model is further described below in combination with specific embodiments.

[0027] For example, Figures 1-4As shown, a cell separation device with the function of protecting cell samples, comprising a hand handle 4, the bottom of the hand handle 4 is fixedly connected with a cover plate assembly 3, the bottom outer surface of the cover plate assembly 3 is threadedly connected with a separation assembly 1, the front surface of the separation assembly 1 is provided with a controller 2, the separation assembly 1 comprises a separation box 11, the top recess bottom middle of the separation box 11 is fixedly installed with a driving motor 12, the output end of the driving motor 12 is fixedly connected with a centrifugal placement assembly 13, the inner wall bottom of the centrifugal placement assembly 13 is provided with a plurality of test tube assemblies 14, the centrifugal placement assembly 13 comprises a placement box 131, the inner wall near the top of the placement box 131 is provided with a threaded groove 132, the top four corners of the placement box 131 are fixedly connected with a sealing rubber layer 136, the inner wall bottom middle of the placement box 131 is fixedly installed with a cold and hot cycle mechanism 135.

[0028] The cold and hot cycle mechanism 135 is controlled by the controller 2 to realize the cold and hot cycle control temperature effect in the inner cavity of the placement box 131, facilitate the placement of the plurality of test tube assemblies 14 in the placement hole 133 in the inner cavity of the placement box 131, make the rubber layer 134 connected with the placement hole 133 inner cavity play the role of extruding and clamping the test tube assembly 14, and make the cover plate assembly 3 threadedly connected with the placement box 131 to improve the multiple cell separation storage and improve the efficiency.

[0029] As shown in Figure 1 , Figure 2 , the front surface of the separation box 11 is fixedly installed with the outer surface of the controller 2, and the inner wall top four corners of the centrifugal placement assembly 13 are threadedly connected with the bottom four corners of the cover plate assembly 3.

[0030] The centrifugal placement assembly 13 top is threadedly connected with the cover plate assembly 3 bottom by the controller 2 auxiliary installation on the front surface of the separation box 11 to realize the cover box and seal the position of the plurality of test tube assemblies 14.

[0031] As shown in Figure 4 , the inner wall bottom of the placement box 131 is provided with a plurality of placement holes 133, the inner wall four corners of the plurality of placement holes 133 are fixedly connected with a rubber layer 134, and the outer surface of the rubber layer 134 is overlapped with the outer surface of the test tube assembly 14.

[0032] The plurality of test tube assemblies 14 are placed through the plurality of placement holes 133 provided on the bottom of the placement box 131, and the rubber layer 134 on the inner wall of the placement hole 133 plays the role of extruding and fixing the position to facilitate the separation effect.

[0033] As shown in Figure 2 , Figure 3 , the inner wall of the threaded groove 132 is threadedly connected with the bottom four corners of the cover plate assembly 3, and the bottom middle of the placement box 131 is fixedly connected with the output end of the driving motor 12.

[0034] The inner wall of the screw groove 132 is threadedly connected with the bottom of the cover plate assembly 3, so that the test tube assembly 14 placed in the cavity of the placing box 131 can fix, press and stabilize the position of the test tube assembly 14, and the driving motor 12 is located in the middle of the bottom of the placing box 131, so as to drive the centrifugal placing assembly 13 to rotate and separate cells.

[0035] As shown in Figure 3 , Figure 4 , the plurality of test tube assemblies 14 include a plurality of centrifugal test tubes 141, the outer surfaces of the plurality of centrifugal test tubes 141 are lapped with the inner walls of the plurality of placing holes 133, the inner walls of the top portions of the plurality of centrifugal test tubes 141 are all inserted with sealing covers 142, and the outer surfaces of the sealing covers 142 are provided with friction patterns 143.

[0036] The plurality of centrifugal test tubes 141 are placed in the inner walls of the plurality of placing holes 133, and the sealing covers 142 are inserted into the cavities of the plurality of centrifugal test tubes 141, so as to better seal the centrifugal test tubes 141 and facilitate separation, and the friction patterns 143 provided on the outer surfaces of the sealing covers 142 can prevent slipping and facilitate the taking and using of the sealing covers 142.

[0037] As shown in Figure 5 , the cover plate assembly 3 includes a cover plate 31, the top portion of the cover plate 31 is fixedly connected with the bottom of the hand-held handle 4, the bottom of the cover plate 31 is provided with a threaded block 32 around, and the outer surface of the threaded block 32 is threadedly connected with the inner wall of the screw groove 132.

[0038] The hand-held handle 4 is used to take and drive the rotation of the cover plate 31, so as to facilitate the threaded connection of the threaded block 32 with the top of the placing box 131.

[0039] As shown in Figure 5 , the bottom of the cover plate 31 is fixedly connected with a pressing block 33 around, and the bottom of the pressing block 33 is lapped with the top of the sealing rubber layer 136.

[0040] The pressing block 33 also serves to press the sealing rubber layer 136 to improve sealing and prevent internal airflow from leaking.

[0041] The working principle of the utility model is as follows: the controller 2 controls the cold and hot circulation mechanism 135 to control the temperature in the cavity of the placing box 131, the plurality of test tube assemblies 14 are placed in the bottom placing holes 133 in the cavity of the placing box 131, the rubber layer 134 connected with the cavity of the placing hole 133 serves to extrude and clamp the test tube assembly 14, and the cover plate assembly 3 is threadedly connected with the inner wall of the top of the placing box 131, so as to improve the storage of multiple cells and improve the efficiency.

[0042] The basic principle and main features of the present application and the advantages of the present application are shown and described above. Those skilled in the art should understand that the present application is not limited by the above examples, and the above examples and descriptions in the specification are only to illustrate the principles of the present application. Without departing from the spirit and scope of the present application, various changes and improvements can be made to the present application, and these changes and improvements all fall within the scope of the present application. The scope of protection of the present application is defined by the appended claims and their equivalents.

Claims

1. A cell separation device with the function of protecting cell samples, comprising a handle (4), characterized in that: The bottom of the handle (4) is fixedly connected to a cover plate assembly (3), and the bottom outer surface of the cover plate assembly (3) is threadedly connected to a separation assembly (1). The front of the separation assembly (1) is provided with a controller (2). The separation component (1) includes a separation box (11), a drive motor (12) is fixedly installed in the middle of the bottom of the top groove of the separation box (11), the output end of the drive motor (12) is fixedly connected to a centrifugal placement component (13), and a number of test tube components (14) are provided at the bottom of the inner wall of the centrifugal placement component (13). The centrifugal placement assembly (13) includes a placement box (131). The inner wall of the placement box (131) is provided with threaded grooves (132) around the top. A sealant layer (136) is fixedly connected to the bottom of the top of the placement box (131). A hot and cold circulation mechanism (135) is fixedly installed in the middle of the bottom of the inner wall of the placement box (131).

2. The cell separation device with cell sample protection function according to claim 1, characterized in that: The front of the separation box (11) is fixedly installed on the outer surface of the controller (2), and the top periphery of the inner wall of the centrifugal placement assembly (13) is threadedly connected to the bottom periphery of the cover plate assembly (3).

3. The cell separation device with cell sample protection function according to claim 1, characterized in that: The bottom of the inner wall of the placement box (131) is provided with a number of placement holes (133), and a rubber layer (134) is fixedly connected to the inner wall of the number of placement holes (133). The outer surface of the rubber layer (134) overlaps with the outer surface of the test tube assembly (14).

4. The cell separation device with cell sample protection function according to claim 1, characterized in that: The inner wall of the threaded groove (132) is threaded to the bottom periphery of the cover plate assembly (3), and the bottom center of the placement box (131) is fixedly connected to the output end of the drive motor (12).

5. A cell separation device with cell sample protection function according to claim 1, characterized in that: The plurality of test tube assemblies (14) include a plurality of centrifuge tubes (141), the outer surface of the plurality of centrifuge tubes (141) overlaps with the inner wall of a plurality of placement holes (133), and a sealing cap (142) is inserted into the top inner wall of each of the plurality of centrifuge tubes (141), and the outer surface of the sealing cap (142) is provided with friction texture (143).

6. A cell separation device with cell sample protection function according to claim 5, characterized in that: The cover plate assembly (3) includes a cover plate (31), the top of which is fixedly connected to the bottom of the handle (4), and threaded blocks (32) are provided around the bottom of the cover plate (31), with the outer surface of the threaded blocks (32) threadedly connected to the inner wall of the threaded groove (132).

7. A cell separation device with cell sample protection function according to claim 6, characterized in that: A pressure block (33) is fixedly connected around the bottom of the cover plate (31), and the bottom of the pressure block (33) overlaps with the top of the sealant layer (136).

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