Ultrasonic cell crusher
By introducing sound insulation panels, cooling pipe assemblies, and lifting devices into the ultrasonic cell disruptor, noise and temperature control issues were resolved, ensuring the stability of the reaction vessel and achieving low noise, temperature control, and safe operation.
Patent Information
- Application Number
- CN202423046820.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-11
- Publication Date
- 2025-11-21
- Estimated Expiration
- 2034-12-11
AI Technical Summary
Existing ultrasonic cell disruptors are prone to generating high noise and temperature rise during operation, and the reaction containers are easily vibrated or dropped, affecting sample stability and the health of operators.
An ultrasonic cell disruptor was designed, comprising a housing, a door, a middle partition, a mounting base, a cooling pipe assembly, and a lifting device, combined with a sound insulation panel and a clamping structure, to reduce noise, control temperature, and stabilize the reaction vessel.
It effectively reduces noise, controls temperature, ensures the stability of the reaction vessel, prevents it from falling, and improves sample stability and operational safety.
Smart Images
Figure CN223576503U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model belongs to ultrasonic cell crushing technical field relates to an ultrasonic cell disruptor. BACKGROUND
[0002] Ultrasonic cell disruptor (Ultrasonic Cell Disruptor) is a kind of equipment using ultrasonic energy to break cell, is widely used in biology, medicine, chemistry and food science etc. It is broken through the formation of cavitation effect in liquid medium by generating high-intensity ultrasonic waves, thereby destroying cell wall and cell membrane, releasing the substance in cell, such as protein, nucleic acid etc.
[0003] Ultrasonic disruptor works, through electric energy conversion into acoustic energy, and this energy is changed into dense small bubbles and is rapidly burst, plays the role of breaking cell and other substances.In this process, due to the friction of ultrasonic wave in medium propagation, part of energy will be converted into local high heat, and then possibly cause sample temperature to rise, thereby affecting the activity and stability of sample.
[0004] In addition, ultrasonic disruptor works and generates high-intensity acoustic vibration, and these acoustic vibrations produce cavitation effect in liquid, so that liquid temperature can quickly rise, and also generate relatively large noise.Noise radiation has influence on the health of operating personnel, and long-term exposure in high-decibel noise environment can cause damage to hearing, and high-noise environment can also cause interference to laboratory equipment.Meanwhile, the current ultrasonic disruptor does not have fixed protection device for reaction container, and the problem of vibration or even falling of reaction container can easily occur in working process. UTILITY MODEL CONTENTS
[0005] The utility model aims at solving above-mentioned problem, provides a kind of ultrasonic cell disruptor.
[0006] To achieve the above object, the utility model provides a kind of ultrasonic cell disruptor, including box and with the opening and closing door of box cooperation, the middle partition of box middle part is equipped with, the bottom of box is equipped with mounting seat, the mounting seat is equipped with installation groove, and the reaction container can be detachably installed in installation groove, the transducer is further above the middle partition, the transducer is connected with amplitude lever, and the amplitude lever passes through the middle partition and extends into the reaction container, and the cooling pipe group is equipped in the mounting seat.
[0007] Further, the inner wall of the box on the lower side of the middle partition is respectively provided with left sound baffle, right sound baffle and middle sound baffle.
[0008] Further, the cooling pipe group comprises a plurality of pipe layers arranged in vertical direction and connected in communication, and the cooling medium in adjacent pipe layers flows in opposite directions;
[0009] The uppermost pipe layer is connected with a water inlet pipe, and the lowermost pipe layer is connected with a water outlet pipe, the water inlet pipe and the water outlet pipe penetrating through the intermediate sound insulation board and the box body and extending out of the box body to be connected with a circulating cooling water supply mechanism.
[0010] Further, lifting devices are symmetrically arranged on both sides of the mounting seat, and a pressing plate structure is arranged on the lifting device, and the pressing plate structure is used for pressing the reaction container.
[0011] The ultrasonic cell disruptor has the following beneficial effects:
[0012] The ultrasonic cell disruptor has the following beneficial effects: BRIEF DESCRIPTION OF DRAWINGS
[0013] Figure 1 Fig. 1 is a perspective view of an ultrasonic cell disruptor according to an embodiment of the present application;
[0014] Figure 2 Fig. 2 is a front view of the ultrasonic cell disruptor according to the embodiment of the present application;
[0015] Figure 3 Fig. 3 is a perspective view of the ultrasonic cell disruptor according to the embodiment of the present application; Figure 2
[0016] Figure 4 Fig. 4 is a structural view of a cooling pipe group according to the embodiment of the present application.
[0017] The meanings of the reference signs in the drawings are as follows:
[0018] 1, box body; 2, opening and closing door; 3, intermediate partition; 4, mounting seat; 41, mounting groove; 5, reaction container; 6, transducer; 7, amplitude rod; 8, cooling pipe group; 11, left sound insulation board; 12, right sound insulation board; 13, intermediate sound insulation board; 81, water inlet pipe; 82, water outlet pipe; 9, lifting device; 91, pressing plate structure. DETAILED DESCRIPTION
[0019] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the following will briefly introduce the drawings needed in the embodiments. Obviously, the drawings in the following description only constitute some embodiments of the present application, and for those skilled in the art, other drawings can also be obtained from these drawings without creative labor.
[0020] The present application will be described in detail below in conjunction with the drawings and specific embodiments. The embodiments cannot be exhaustively described here, but the embodiments of the present application are not limited to the following embodiments.
[0021] In combination with Figures 1-4 As shown in the drawings, the present application provides an ultrasonic cell disruptor, which comprises a box body 1, an opening and closing door 2, an intermediate partition plate 3, a mounting seat 4, a reaction container 5, a transducer 6, an amplitude-varying rod 7, a cooling pipe group 8 and a lifting device.
[0022] According to an embodiment of the present application, the opening and closing door 2 cooperates with the box body 1. When the crushing operation is needed, the sample is put into the box body 1 by opening the opening and closing door 2, and then the opening and closing door 2 is closed. The crushing operation is performed through the operation panel arranged on the outer side of the opening and closing door 2. In this embodiment, the intermediate partition plate 3 is arranged in the middle of the box body. The intermediate partition plate 3 divides the box body 1 into two parts. The mounting seat 4 is arranged in the lower part of the box body 1. Specifically, the mounting seat 4 is arranged on the inner bottom of the box body 1. The mounting seat 4 is provided with a mounting groove 41 in the middle. The reaction container 5 is placed on the mounting groove 41 and extends out of the mounting groove 41. The transducer 6 is arranged above the intermediate partition plate 3. The transducer 6 is connected with the amplitude-varying rod 7. The amplitude-varying rod 7 extends into the reaction container 5 through the intermediate partition plate 3. In addition, the inner wall of the box body 1 on the lower side of the intermediate partition plate 3 is respectively provided with a left soundproof plate 11, a right soundproof plate 12 and a middle soundproof plate 13.
[0023] The ultrasonic cell disruptor of the present application can effectively reduce the production noise during crushing by arranging the reaction container 5 in the mounting groove 41. In combination with the arrangement of the left soundproof plate 11, the right soundproof plate 12 and the middle soundproof plate 13, the production noise can be further reduced.
[0024] According to an embodiment of the present application, the mounting seat 4 is provided with the cooling pipe group 8. The cooling pipe group 8 comprises a plurality of pipe layers arranged in the vertical direction and connected in series. The flow directions of the cooling medium in the adjacent pipe layers are opposite, such as Figure 4As shown, in the present embodiment, the cooling pipe group 8 is provided with four layers of pipe layers, and the pipes in each layer are connected through connecting pipes, and the connecting pipes in each layer are connected at different positions to ensure that the flow directions of the cooling water in the adjacent pipe layers are opposite, that is, the cooling water in the uppermost pipe layer flows in a counterclockwise direction, then enters the second layer pipe layer through the connecting pipe, the cooling water in the second layer pipe layer flows in a clockwise direction, the cooling water in the third layer pipe layer flows in a counterclockwise direction, and the cooling water in the fourth layer pipe layer flows in a clockwise direction. The uppermost pipe layer is connected with a water inlet pipe 81, and the lowermost pipe layer is connected with a water outlet pipe 82, and the water inlet pipe 81 and the water outlet pipe 82 pass through the intermediate sound insulation plate 13 and the box body 1 and extend out of the box body 1 to be connected with a circulating cooling water supply mechanism (not shown in the figure). The cooling water enters from the water inlet pipe 81, is discharged from the water outlet pipe 82 after heat exchange, so that the temperature control during crushing can be ensured, and the problem of affecting the stability of the sample due to the temperature being too high can be avoided.
[0025] According to an embodiment of the utility model, the mounting seat 4 of the utility model is provided with lifting devices 9 symmetrically on both sides, the lifting devices 9 are provided with pressing plate structures 91, and the pressing plate structures 91 are used for pressing the reaction container 5.
[0026] The ultrasonic cell disruptor of the utility model is provided with the lifting devices 9 and the pressing plate structures 91, when crushing is needed, the pressing plate structures 91 press the two sides of the reaction container 5, and the problem that the reaction container vibrates or even falls is avoided. After work is finished, the pressing plate 91 is loosened, the reaction container 5 is taken out from the mounting groove 41, and subsequent processes are carried out, so that the operation is convenient and reliable.
[0027] The above only describes one embodiment of the utility model and is not used for limiting the utility model. For those skilled in the art, the utility model can have various changes and changes. Any modification, equivalent replacement, improvement, etc. within the spirit and principles of the utility model should be included in the protection scope of the utility model.
Claims
1. An ultrasonic cell disrupter comprising a cabinet (1) and a door (2) which opens and closes in cooperation with the cabinet (1), and an intermediate partition (3) provided in the middle of the cabinet (1), characterized in that, The box bottom is provided with a mounting seat (4), the mounting seat (4) is provided with a mounting groove (41), a reaction container (5) is detachably mounted in the mounting groove (41), a transducer (6) is further arranged above the intermediate partition plate (3), the transducer (6) is connected with a amplitude changing rod (7), the amplitude changing rod (7) penetrates through the intermediate partition plate (3) and extends into the reaction container (5), and the mounting seat (4) is provided with a cooling pipe group (8).
2. The ultrasonic cell disrupter according to claim 1, wherein The inner wall of the box (1) on the lower side of the intermediate partition plate (3) is respectively provided with a left soundproof board (11), a right soundproof board (12) and an intermediate soundproof board (13).
3. The ultrasonic cell disrupter of claim 2, wherein, The cooling pipe group (8) comprises a plurality of pipe layers arranged in a vertical direction and connected in communication, and the flow directions of the cooling medium in adjacent pipe layers are opposite; The uppermost pipe layer is connected with a water inlet pipe (81), and the lowermost pipe layer is connected with a water outlet pipe (82), the water inlet pipe (81) and the water outlet pipe (82) penetrate through the intermediate soundproof board (13) and the box (1) and extend out of the box (1) to be connected with a circulating cooling water supply mechanism.
4. The ultrasonic cell disrupter according to claim 1 or 3, characterized in that, Lifting devices (9) are symmetrically arranged on both sides of the mounting seat (4), the lifting devices (9) are mounted with a pressing plate structure (91), and the pressing plate structure (91) is used for pressing the reaction container (5).