Automatic sample injection tray of flow cytometer

By incorporating a rubber air bladder ring and a rotating compression threaded column within the insertion port of the flow cytometer's automated sample loading tray, the problem of cell tube misalignment was solved, thus achieving both accuracy and stability in detection.

CN223581706UActive Publication Date: 2025-11-21SUZHOU TUAN BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202423065295.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-12
Publication Date
2025-11-21
Estimated Expiration
2034-12-12

AI Technical Summary

Technical Problem

Cell tubes are prone to tilting when inserted into the automated sample tray of a flow cytometer, leading to inaccurate detection.

Method used

A rubber air bladder ring is installed on the inner wall of the insertion port of the flow cytometer's automatic sample loading tray. By connecting the air tube and the inner lining telescopic body and the rotating extrusion threaded column, the air bladder ring expands to center the cell placement tube and prevent it from tilting.

Benefits of technology

It effectively prevents the cell placement tube opening from tilting, ensures detection accuracy, and improves the usability of the flow cytometer's automatic sample loading tray.

✦ Generated by Eureka AI based on patent content.

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    Figure CN223581706U_ABST
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Abstract

The utility model discloses an automatic sample injection tray of a flow cytometer. The automatic sample injection tray comprises a flow cytometer device body and a placement structure arranged on the side surface of the flow cytometer device body, a connecting ventilation pipe is arranged on the side face of the rubber air bag ring, a rotating extrusion threaded column is arranged at the upper end of the interior connecting telescopic body and connected with the interior connecting telescopic body through a rotating shaft, and the interior connecting telescopic body can be extruded by rotating the rotating extrusion threaded column. After the interior connecting telescopic body is extruded, internal gas can enter a rubber air bag ring along a connecting ventilation pipe to expand the rubber air bag ring, and the expanded rubber air bag ring can extrude a cell placement pipe inserted into an insertion placement opening to enable the cell placement pipe to be placed at a central position; meanwhile, the cell placing tubes are limited, so that the tube openings of the cell placing tubes are prevented from inclining when the mobile supporting chassis moves, and the use practicability of the automatic sample injection tray of the flow cytometer is effectively improved.
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Description

TECHNICAL FIELD

[0001] The utility model belongs to the medical research and inspection related technical field, concretely relates to a flow cytometer automatic sample feeding tray. BACKGROUND

[0002] Flow cytometer is a kind of detection means that carries out quantitative analysis and sorting to single cell or other biological particles on functional level, it is integrated with electron, computer, laser, fluid theory, is praised as " CT " of laboratory.

[0003] Flow cytometer has been widely applied in immunology, hematology, oncology, cell biology, cytogenetics, biochemistry and other clinical medical and basic medical research fields.For example, it can be used for the typing of leukemia, the determination of tumor cell chromosome heteroploidy, and immunology research, and has begun to be used for bacterial identification, virus-infected cell identification and AIDS-infected T4, T8 cell counting.

[0004] Flow cytometer automatic sample feeding tray is an accessory for flow cytometer, which can realize the automatic transportation and processing of samples. This tray is usually used with an automatic sample feeder, can load multiple samples at a time, and meets the needs of high-throughput analysis. The design of automatic sample feeding tray helps to reduce human error, improve analysis efficiency and optimize experimental process. It can handle various types of samples, including liquid, gas or solid solution, and is suitable for various detection standards and analysis methods.

[0005] However, the cell tube is prone to be skewed when being inserted and placed into the flow cytometer automatic sample feeding tray due to the gap between the cell tube and the inner side of the placement slot. The skewed tube opening can cause the detection cell liquid to flow out or the detection port to be difficult to align, resulting in inaccurate data.

[0006] The utility model improves the above problems, and specifically relates to a flow cytometer automatic sample feeding tray capable of stably placing a cell placement tube. INVENTION CONTENTS

[0007] The utility model aims at providing a flow cytometer automatic sample feeding tray to solve the problem that the cell tube is prone to be skewed when being inserted and placed into the flow cytometer automatic sample feeding tray due to the gap between the cell tube and the inner side of the placement slot. The skewed tube opening can cause the detection cell liquid to flow out or the detection port to be difficult to align, resulting in inaccurate data.

[0008] To achieve the above object, the utility model provides the following technical scheme: a flow cytometer automatic sample feeding tray, comprising a flow cytometer device body and a placement structure arranged at the side surface position of the flow cytometer device body.

[0009] The middle position of the placing structure is provided with a moving support base;

[0010] The middle position of the moving support base is provided with a sample feeding tray;

[0011] The sample feeding tray is provided with a plug-in accommodation port;

[0012] The inner side wall position of the plug-in accommodation port is provided with a rubber airbag ring, the side position of the rubber airbag ring is provided with a connecting air pipe, the middle end position of the connecting air pipe is provided with an interior decoration connecting telescopic body, the upper end position of the interior decoration connecting telescopic body is provided with a rotating extrusion threaded column, the rotating extrusion threaded column is connected with the interior decoration connecting telescopic body through a rotating shaft, the rotating extrusion threaded column is connected with the sample feeding tray through threads, rotating the rotating extrusion threaded column can extrude the interior decoration connecting telescopic body, and after the interior decoration connecting telescopic body is extruded, the gas in the interior decoration connecting telescopic body enters the rubber airbag ring along the connecting air pipe to make the rubber airbag ring expand.

[0013] Preferably, the upper side position of the rotating extrusion threaded column is provided with an upper connecting rotating block, and the upper connecting rotating block and the rotating extrusion threaded column are in an integral structure.

[0014] Preferably, the upper side position of the placing structure is provided with an upper connecting acrylic cover, and the upper connecting acrylic cover is connected with the placing structure in a plug-in clamping mode.

[0015] Preferably, the upper side position of the flow cytometer device body is provided with a cytometer upper connecting cover, and the cytometer upper connecting cover is connected to the upper side of the flow cytometer device body in a covering clamping mode.

[0016] Preferably, the side position of the cytometer upper connecting cover is provided with a cocking groove, and the cocking groove is in an arc structure.

[0017] Preferably, the front side position of the flow cytometer device body is provided with a start button, and the start button controls the start and stop of the flow cytometer device body.

[0018] Preferably, the bottom position of the flow cytometer device body is provided with a bottom connecting support leg, the bottom connecting support leg is connected with the flow cytometer device body through a threaded column, and the bottom outer side of the bottom connecting support leg is made of rubber material.

[0019] Compared with the prior art, the flow cytometer automatic sample feeding tray has the following beneficial effects:

[0020] The inner side wall position of the plug-in placement opening is provided with a rubber air bag ring, the side position of the rubber air bag ring is provided with a connecting air pipe, the middle end position of the connecting air pipe is provided with an interior decoration connecting telescopic body, the upper end position of the interior decoration connecting telescopic body is provided with a rotating extrusion threaded column, the rotating extrusion threaded column is connected with the interior decoration connecting telescopic body through a rotating shaft, and the rotating extrusion threaded column is rotationally connected with the placement sample tray through a thread. BRIEF DESCRIPTION OF DRAWINGS

[0021] Figure 1 It is the flow cytometer automatic sample tray and cell instrument without upper connection acrylic cover structure schematic diagram of the utility model.

[0022] Figure 2 It is the flow cytometer automatic sample tray and cell instrument whole structure schematic diagram of the utility model.

[0023] Figure 3 It is the flow cytometer automatic sample tray serial number A position enlarged structure schematic diagram of the utility model.

[0024] Figure 4 It is the flow cytometer automatic sample tray serial number A position front view cross section structure schematic diagram of the utility model.

[0025] In the figure: 1, flow cytometer device body; 2, cell instrument upper connection cover; 3, trigger groove; 4, start button; 5, placement structure; 6, bottom connection support leg; 7, upper connection acrylic cover; 8, placement sample tray; 9, plug-in placement opening; 10, mobile support base plate; 11, rotating extrusion threaded column; 12, upper connection rotating block; 13, rubber air bag ring; 14, interior decoration connecting telescopic body; 15, connecting air pipe. DETAILED DESCRIPTION

[0026] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the protection scope of the utility model.

[0027] This utility model provides, for example Figures 1-4 As shown, an automated sample loading tray for a flow cytometer includes a flow cytometer body 1 and a placement structure 5 located on the side of the flow cytometer body 1; a movable support base 10 is located in the middle of the placement structure 5; a sample loading tray 8 is located in the middle of the movable support base 10; the sample loading tray 8 has an insertion port 9; a rubber air bladder ring 13 is located on the inner wall of the insertion port 9; a connecting vent pipe 15 is located on the side of the rubber air bladder ring 13; an inner connecting telescopic body 14 is located at the middle end of the connecting vent pipe 15; and a rotating extrusion threaded column 11 is located at the upper end of the inner connecting telescopic body 14. The column 11 is connected to the interior connecting telescopic body 14 via a rotating shaft. Rotating the threaded column 11 allows it to be rotated and connected to the sample inlet tray 8 via threads. Rotating the threaded column 11 can compress the interior connecting telescopic body 14. After being compressed, the gas inside the interior connecting telescopic body 14 will enter the rubber air bladder ring 13 along the connecting vent pipe 15, causing it to expand. The expanded rubber air bladder ring 13 will compress the cell placement tube inserted into the insertion port 9, ensuring that it is placed in the center position. At the same time, it restricts the cell placement tube from becoming skewed when the moving support chassis 10 moves, thereby effectively improving the usability of the flow cytometer's automatic sample inlet tray.

[0028] like Figure 3 As shown, an upper connecting rotating block 12 is provided on the upper side of the rotating extrusion threaded column 11. The upper connecting rotating block 12 and the rotating extrusion threaded column 11 are an integral structure. The upper connecting rotating block 12 provides a position for the hand to hold, making it convenient for the user to rotate the rotating extrusion threaded column 11 for corresponding adjustments.

[0029] like Figure 3 As shown, an upper connecting acrylic cover 7 is provided on the upper side of the placement structure 5 near the left end. The upper connecting acrylic cover 7 is connected to the placement structure 5 by a plug-in snap-fit ​​method. The upper connecting acrylic cover 7 can be used to cover the placement structure 5 when it is not in use to prevent dust from entering and affecting the subsequent testing results.

[0030] like Figure 3 As shown, a cell analyzer upper connection cover 2 is provided on the upper side of the flow cytometer device body 1. The cell analyzer upper connection cover 2 is connected to the upper side of the flow cytometer device body 1 by a cover snap-fit ​​method. A latching groove 3 is provided on the side of the cell analyzer upper connection cover 2. The latching groove 3 has an arc-shaped structure and provides a position for the user to latch. After the cell analyzer upper connection cover 2 is removed, the staff can inspect and repair the internal components of the flow cytometer device body 1.

[0031] like Figure 3As shown, a start button 4 is located on the front side of the flow cytometer device 1. The start button 4 controls the start and stop of the flow cytometer device 1. When the start button 4 starts the flow cytometer device 1, its data will be displayed on an external display device. The flow cytometer device 1 can also be operated and controlled by an external device. When the start button 4 is pressed again, the flow cytometer device 1 will be turned off, and the external device will lose the signal from the flow cytometer device 1.

[0032] like Figure 3 As shown, a bottom connecting support leg 6 is provided at the bottom of the flow cytometer device body 1. The bottom connecting support leg 6 is connected to the flow cytometer device body 1 by rotating through a threaded post. The outer bottom surface of the bottom connecting support leg 6 is made of rubber. The rotational connection of the threaded post of the bottom connecting support leg 6 is quick and can improve installation efficiency. The rubber material on the outer bottom surface of the bottom connecting support leg 6 can increase the friction between the bottom connecting support leg 6 and the placement surface, thereby making the flow cytometer device body 1 more stable.

[0033] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. An automated sample loading tray for a flow cytometer, comprising: The flow cytometer device body (1) and the placement structure (5) provided on the side of the flow cytometer device body (1); A movable support chassis (10) is provided at the middle position of the placement structure (5). A sample inlet tray (8) is provided at the middle position of the mobile support chassis (10). The sample placement tray (8) is provided with a plug-in placement port (9); Its features are: A rubber airbag ring (13) is provided on the inner wall of the insertion port (9). A connecting vent pipe (15) is provided on the side of the rubber airbag ring (13). An interior connecting telescopic body (14) is provided at the middle end of the connecting vent pipe (15). A rotating extrusion threaded column (11) is provided at the upper end of the interior connecting telescopic body (14). The rotating extrusion threaded column (11) is connected to the interior connecting telescopic body (14) through a rotating shaft. The rotating extrusion threaded column (11) is rotatably connected to the sample tray (8) through a thread. Rotating the rotating extrusion threaded column (11) can extrude the interior connecting telescopic body (14). After the interior connecting telescopic body (14) is extruded, the gas inside will enter the rubber airbag ring (13) along the connecting vent pipe (15) and cause it to expand.

2. The automated sample loading tray for a flow cytometer according to claim 1, characterized in that: An upper connecting rotating block (12) is provided on the upper side of the rotating extrusion threaded column (11), and the upper connecting rotating block (12) and the rotating extrusion threaded column (11) are an integral structure.

3. The automated sample loading tray for a flow cytometer according to claim 1, characterized in that: An upper connecting acrylic cover (7) is provided on the upper side of the placement structure (5) near the left end. The upper connecting acrylic cover (7) is connected to the placement structure (5) by a plug-in snap-fit ​​method.

4. The automated sample loading tray for a flow cytometer according to claim 1, characterized in that: The flow cytometer device body (1) is provided with a cell instrument upper connection cover (2) at the upper side, and the cell instrument upper connection cover (2) is connected to the upper side of the flow cytometer device body (1) by a cover snap-fit ​​method.

5. The automated sample loading tray for a flow cytometer according to claim 4, characterized in that: A latching groove (3) is provided on the side of the connecting cover (2) of the cell instrument. The latching groove (3) has an arc-shaped structure.

6. The automated sample loading tray for a flow cytometer according to claim 1, characterized in that: A start button (4) is provided on the front side of the flow cytometer device (1), and the start button (4) controls the start and stop of the flow cytometer device (1).

7. The automated sample loading tray for a flow cytometer according to claim 1, characterized in that: The flow cytometer device body (1) is provided with a bottom connecting support leg (6) at the bottom position. The bottom connecting support leg (6) is connected to the flow cytometer device body (1) by rotating through a threaded column. The bottom outer surface of the bottom connecting support leg (6) is made of rubber material.