Experimental freeze dryer

By introducing a sampling device and linkage mechanism into the freeze dryer, sealed sampling and omnidirectional sampling of bottles with rubber stoppers are realized, solving the problems of limited applicability and insufficient angle of movement of existing devices, and improving sampling efficiency and reliability.

CN223592365UActive Publication Date: 2025-11-25TRUKING TECH LTD
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Patent Information

Application Number
CN202520038315.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-01-07
Publication Date
2025-11-25
Estimated Expiration
2035-01-07

AI Technical Summary

Technical Problem

Existing sampling devices can only grab the bottle body and cannot re-stop bottles with rubber stoppers, which limits their applicability and the limited range of motion, making it impossible to cover bottles in all positions inside the freeze dryer, resulting in incomplete monitoring.

Method used

An experimental freeze dryer was designed, comprising a sampling device, a stopper, and a bottle outlet channel. The stopper drives the sampling mechanism through a linkage mechanism to achieve sealing and gripping of the bottle. The sampling rod is extended and retracted through a guide tube and a handle assembly. Combined with a flexible support tube and a bracket, the sampling range is expanded.

Benefits of technology

It enables sealed sampling and omnidirectional sampling of bottles with rubber stoppers. Its simple and compact structure improves sampling efficiency and reliability, expands the sampling range, and meets experimental requirements.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses an experimental type freeze dryer which comprises a box body, a sampling device and a window arranged on the box body, the sampling device comprises a sampling mechanism, a plug pressing piece and a bottle outlet channel, the plug pressing piece drives the sampling mechanism to act through a linkage mechanism, and the bottle outlet channel is arranged on one side of the window. During sampling, the cork pressing piece is used for pressing a cork into a bottle body and sealing the bottle body, meanwhile, the cork pressing piece drives the sampling mechanism to act through the linkage mechanism to grab the bottle body, then the grabbed bottle body can be taken out from the bottle outlet channel on one side of the window, and the cork pressing device is simple and compact in structure and can be used for the bottle body needing cork pressing.
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Description

TECHNICAL FIELD

[0001] The utility model relates to food, medicine packing equipment especially, relate to an experimental freeze dryer. BACKGROUND

[0002] Compared with batch products, experimental medicine is usually expensive and difficult to reproduce, for pharmaceutical manufacturers to explore new technology, need to frequently use sampling device to grab the freeze-dried samples in the freeze-drying box in each time period of the vial, so as to carry out observation and research, for example, analysis and analysis of moisture content in medicine under different vacuum degree and temperature of drying and sublimation drying. The existing sampling device is relatively single in function, can only grab the bottle body, cannot plug the bottle body with rubber plug, the scope of application will be limited, and after entering the freeze dryer, the activity angle is limited, cannot cover the bottle body at each position of the board layer, which is not conducive to monitoring the freeze-drying condition of the vial at each position of the board layer. SUMMARY

[0003] The utility model wants to solve the technical problem that the prior art is overcome, provide a simple structure, the experimental freeze dryer that sampling bottle can plug the sample bottle simultaneously.

[0004] To solve the above technical problems, the utility model adopts the following technical scheme:

[0005] An experimental freeze dryer, including box, sampling device and being located on the window of box, the sampling device includes sampling mechanism, plugger and bottle outlet channel, the plugger drives the sampling mechanism to act through linkage mechanism, the bottle outlet channel is located at one side of the window.

[0006] As a further improvement of the above technical scheme: the sampling device further includes a sampling rod and a guide tube provided on the outer periphery of the sampling rod, the guide tube is provided in the window, one end of the guide tube located outside the box is connected with one end of the sampling rod located outside the box through a handle assembly for driving the sampling rod to extend and retract, the other end of the guide tube is provided with a mounting portion, the plugger and the sampling mechanism are provided in the mounting portion, the other end of the sampling rod is provided with a plugger portion for pressing the plugger when extending and retracting.

[0007] As a further improvement of the above technical scheme: the handle assembly includes a first handle, a second handle, a first connecting rod and a second connecting rod, the first handle and the second handle are hingedly connected with the guide tube, one end of the first connecting rod is hingedly connected with the first handle, the other end of the first connecting rod is hingedly connected with the sampling rod, one end of the second connecting rod is hingedly connected with the second handle, the other end of the second connecting rod is hingedly connected with the sampling rod.

[0008] As a further improvement to the above technical solution: the second handle is provided with a ratchet rack, and the first handle is provided with a pawl that can cooperate with the ratchet rack and a latch for engaging or disengaging the pawl from the ratchet rack.

[0009] As a further improvement to the above technical solution: the handle assembly further includes a third link, the pawl and the latch are both hinged to the first handle, one end of the third link is hinged to the latch, and the other end of the third link is hinged to the pawl.

[0010] As a further improvement to the above technical solution: the mounting part is provided with a pressure rod, the upper end of the pressure rod is provided with a roller, the roller abuts against the pressure plug part, the lower end of the pressure rod is connected to the pressure plug, and the mounting part is provided with an elastic reset member for moving the pressure rod upward.

[0011] As a further improvement to the above technical solution: the sampling mechanism includes a plurality of grippers arranged around the plug, and the grippers are hinged to the mounting part.

[0012] As a further improvement to the above technical solution: the linkage mechanism includes multiple fourth links, one end of each of the multiple fourth links is hinged to one of the multiple grippers, and the other end of the fourth link is hinged to the pressure plug.

[0013] As a further improvement to the above technical solution: the plunger part is formed by bending the sampling rod downwards.

[0014] As a further improvement to the above technical solution: the side of the viewing window away from the housing is provided with a flexible support tube through which the sampling device passes and a bracket for providing support for the flexible support tube, and the bracket is detachably connected to the viewing window.

[0015] Compared with the prior art, the advantages of this utility model are:

[0016] The experimental freeze dryer disclosed in this utility model includes a sampling device comprising a stopper, a sampling mechanism, and a bottle outlet channel. The stopper drives the sampling mechanism via a linkage mechanism. During sampling, the stopper presses the stopper into the bottle body to seal it. Simultaneously, the stopper, through the linkage mechanism, drives the sampling mechanism to grasp the bottle body. The grasped bottle body can then be removed from the bottle outlet channel on one side of the viewing window. The structure is simple and compact, and can be used for bottles that require stoppering.

[0017] Other features and advantages of this invention will be described in detail in the following detailed description section. Attached Figure Description

[0018] Figure 1 This is a first-view three-dimensional structural diagram of the sampling device in this utility model.

[0019] Figure 2 This is a three-dimensional structural diagram of the sampling device in this utility model from a second perspective.

[0020] Figure 3 This is a cross-sectional structural diagram of the experimental freeze dryer of this utility model in use.

[0021] Figure 4 yes Figure 3 Enlarged view of point A in the middle.

[0022] Figure 5 This is a three-dimensional structural diagram of the stopper, sampling mechanism, and linkage mechanism in this utility model.

[0023] The labels in the diagram represent:

[0024] 1. Sampling rod; 11. Stopper; 2. Guide tube; 21. Mounting part; 3. Handle assembly; 31. First handle; 32. Second handle; 33. First connecting rod; 34. Second connecting rod; 35. Pawl; 36. Ratchet; 37. Lock; 38. Third connecting rod; 4. Sampling mechanism; 41. Gripper; 5. Linkage mechanism; 51. Fourth connecting rod; 6. Stopper; 61. Pressure rod; 62. Elastic reset component; 63. Roller; 7. Box body; 71. Flexible support tube; 72. Bracket; 73. Ball valve; 74. Bottle outlet channel; 75. Clamp; 76. Air inlet; 77. Viewing window; 78. Plate layer. Detailed Implementation

[0025] In the description of this utility model, it should be understood that the terms "length", "width", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0026] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this utility model, "a plurality of" means two or more, unless otherwise explicitly specified.

[0027] In this utility model, unless otherwise explicitly specified and limited, the terms "assembly," "connection," "joining," and "fixing" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0028] The present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments.

[0029] Figures 1 to 5 This illustration shows one embodiment of the experimental freeze dryer of this invention. The experimental freeze dryer of this embodiment includes a housing 7, a sampling device, and a viewing window 77 disposed on the housing 7. The sampling device includes a sampling mechanism 4, a stopper 6, and a bottle outlet channel 74. The stopper 6 drives the sampling mechanism 4 to move via a linkage mechanism 5. The bottle outlet channel 74 is disposed on one side of the viewing window 77. Preferably, the bottle outlet channel 74 is located below the viewing window 77 to facilitate bottle drop.

[0030] The experimental freeze dryer of this embodiment includes a sampling device comprising a stopper 6, a sampling mechanism 4, and a bottle outlet channel 74. The stopper 6 drives the sampling mechanism 4 via a linkage mechanism 5. During sampling, the stopper 6 presses the stopper into the bottle body to seal it. Simultaneously, the stopper 6, through the linkage mechanism 5, drives the sampling mechanism 4 to grasp the bottle body. The grasped bottle body can then be removed from the bottle outlet channel 74 on one side of the viewing window 77. The structure is simple and compact, and can be used for bottles that require stoppering.

[0031] Furthermore, in this embodiment, the sampling device also includes a sampling rod 1 and a guide tube 2 disposed on the outer periphery of the sampling rod 1. The guide tube 2 passes through the viewing window 77, and one end of the guide tube 2 is located on the outside of the housing 7. Figure 3 The guide tube 2 (located at one end on the right side of the housing 7) and the sampling rod 1 (located at one end on the outside of the housing 7) are connected to a handle assembly 3 for extending and retracting the sampling rod 1. The other end of the guide tube 2 ( Figure 3 The guide tube 2 is located at one end inside the housing 7 and has a mounting part 21. The plug 6 and the sampling mechanism 4 are located at the mounting part 21, and the other end of the sampling rod 1 ( Figure 3The sampling rod 1 (located at one end inside the housing 7) is equipped with a stopper 11 for pressing the stopper 6 during extension and retraction. During sampling, the operator clamps the handle assembly 3, causing the sampling rod 1 to move outward relative to the guide tube 2. The guide tube 2 provides support and guidance for the sampling rod 1. As the sampling rod 1 moves, the stopper 11 presses the stopper 6. At the same time, the stopper 6 drives the sampling mechanism 4 to grab the bottle through the linkage mechanism 5. Then, the operator holds the stoppered bottle and passes it through the housing 7 to the viewing window 77 (during this process, the handle assembly 3 drives the sampling rod 1, guide tube 2, sampling mechanism 4, and bottle to move outward from the housing 7, and the sampling rod 1 and guide tube 2 no longer move relative to each other). The operator then opens the clamping handle assembly 3, and the bottle falls into the bottle outlet channel 74.

[0032] See details Figure 3 After the bottle falls into the bottle outlet channel 74, manually close the ball valve 73 to keep the inside of the freeze dryer chamber 7 sealed. Then, allow air to enter through the air inlet 76 to restore the lower part of the bottle outlet channel 74 to normal pressure. Open the clamp 75 to remove the sample.

[0033] See details Figure 2 In this embodiment, the handle assembly 3 includes a first handle 31, a second handle 32, a first connecting rod 33, and a second connecting rod 34. Both the first handle 31 and the second handle 32 are hinged to the guide tube 2. One end of the first connecting rod 33 is hinged to the first handle 31, and the other end is hinged to the sampling rod 1. One end of the second connecting rod 34 is hinged to the second handle 32, and the other end is hinged to the sampling rod 1. When the operator clamps the first handle 31 and the second handle 32, they move closer together, and simultaneously the first connecting rod 33 and the second connecting rod 34 also move closer together, thereby causing the sampling rod 1 to move relative to the guide tube 2 towards the outside of the housing 7. Conversely, when the operator opens the first handle 31 and the second handle 32, the first connecting rod 33 and the second connecting rod 34 also open, thereby causing the sampling rod 1 to move relative to the guide tube 2 towards the inside of the housing 7. The structure is simple, compact, and has good reliability.

[0034] Furthermore, in this embodiment, the second handle 32 is provided with a ratchet rack 36, and the first handle 31 is provided with a pawl 35 that can cooperate with the ratchet rack 36 and a latch 37 for engaging or disengaging the pawl 35 from the ratchet rack 36. When the operator clamps the first handle 31 and the second handle 32, allowing the sampling mechanism 4 to grasp the bottle, the latch 37 is operated to keep the pawl 35 engaged with the ratchet rack 36. At this time, the operator does not need to continuously clamp the first handle 31 and the second handle 32, and the bottle will not fall, making it more convenient and reliable. When it is necessary to release the bottle, first open the latch 37 to disengage the pawl 35 from the ratchet rack 36, and then the first handle 31 and the second handle 32 can be opened.

[0035] Furthermore, in this embodiment, the handle assembly 3 also includes a third link 38, with the pawl 35 and the latch 37 both hinged to the first handle 31. One end of the third link 38 is hinged to the latch 37, and the other end is hinged to the pawl 35. When the operator clamps the first handle 31 and the second handle 32, the sampling mechanism 4 grasps the bottle, and then presses the latch 37, preventing the pawl 35 from rotating and separating from the ratchet 36, thus maintaining the engagement state. At this time, the operator does not need to continuously clamp the first handle 31 and the second handle 32, and the bottle will not fall. When it is necessary to release the bottle, the latch 37 is opened, allowing the pawl 35 to rotate and separate from the ratchet 36, and then the first handle 31 and the second handle 32 can be opened. The structure is simple and reliable.

[0036] See details Figure 4 and Figure 5 In this embodiment, the mounting part 21 is provided with a pressure rod 61, and the upper end of the pressure rod 61 is provided with a roller 63, which abuts against the stopper part 11. The lower end of the pressure rod 61 is connected to the stopper 6. The mounting part 21 is provided with an elastic reset member 62 for moving the pressure rod 61 upward. When the sampling rod 1 moves relative to the guide tube 2 towards the outside of the box 7, the stopper part 11 presses the pressure rod 61 down through the roller 63 at the upper end of the pressure rod 61. At the same time, the elastic reset member 62 is compressed, and the pressure rod 61 drives the stopper 6 at the lower end to move downward, thereby pressing the rubber stopper into the bottle. When the sampling rod 1 moves relative to the guide tube 2 towards the inside of the box 7, the compressed elastic reset member 62 extends, pushing the pressure rod 61 to move upward and reset. The stopper 6 moves upward and reset with the pressure rod 61. The pressure rod 61 abuts against the stopper part 11 through the roller 63, which helps to reduce frictional resistance and wear. The elastic reset element 62 is preferably a helical spring and is sleeved around the outer periphery of the pressure rod 61. Of course, in other embodiments, it can also be an elastic rope, an elastic rubber block, etc.

[0037] Furthermore, in this embodiment, the sampling mechanism 4 includes a plurality of grippers 41 arranged around the stopper 6, and the grippers 41 are hinged to the mounting portion 21. When the plurality of grippers 41 rotate toward the center, they can effectively grasp the bottle to complete the sampling; conversely, when the plurality of grippers 41 rotate and open to the sides, they can separate from the bottle and release the bottle.

[0038] In this embodiment, the linkage mechanism 5 includes multiple fourth links 51, one end of each fourth link 51 being hinged to a corresponding gripper 41, and the other end of each fourth link 51 being hinged to the pressure plug 6. When the pressure plug 6 moves up and down, it can drive the fourth links 51 to rotate, which in turn drives the grippers 41 to rotate, thus opening or clamping. The structure is simple and reliable. Preferably, the fourth links 51 are arc-shaped links, which facilitates the transmission of the force from the pressure plug 6 to the grippers 41, making the opening and closing action of the grippers 41 smoother.

[0039] In a preferred embodiment, the pressure plug 11 is formed by bending the sampling rod 1 downwards. When the sampling rod 1 extends and retracts in the guide tube 2, the pressure plug 11 can gradually press down the pressure rod 61 or make the pressure rod 61 gradually rise. The structure is simple and the operation is smooth.

[0040] See details Figure 3 In this embodiment, the viewing window 77 is located on the side furthest from the housing 7. Figure 3 The viewing window 77 (located on the right side of the housing 7) is equipped with a flexible support tube 71 through which the sampling device passes (specifically, the sampling rod 1 and guide tube 2 pass through the flexible support tube 71) and a bracket 72 for supporting the flexible support tube 71. The bracket 72 is detachably connected to the viewing window 77 (e.g., through threaded fasteners such as bolts or screws). After removing the bracket 72, the flexibility of the flexible support tube 71 allows the sampling rod 1, guide tube 2, etc., to be rotated at a certain angle, enabling sampling of bottles at different positions on the plate 78. This facilitates monitoring the freeze-drying status of bottles at various positions on the plate 78, rather than being limited to sampling only bottles in front of the housing 7. Preferably, the flexible support tube 71 is made of corrugated tubing, which facilitates bending and extension.

[0041] Although the present invention has been disclosed above with reference to preferred embodiments, it is not intended to limit the present invention. Any person skilled in the art can make many possible variations and modifications to the present invention, or modify it into equivalent embodiments, without departing from the scope of the present invention. Therefore, any simple modifications, equivalent changes, and modifications made to the above embodiments based on the technical essence of the present invention, without departing from the content of the present invention, should fall within the protection scope of the present invention.

Claims

1. An experimental freeze dryer, characterized in that: It includes a housing (7), a sampling device and a viewing window (77) on the housing (7). The sampling device includes a sampling mechanism (4), a stopper (6) and a bottle outlet channel (74). The stopper (6) drives the sampling mechanism (4) to move through a linkage mechanism (5). The bottle outlet channel (74) is located on one side of the viewing window (77).

2. The experimental freeze dryer according to claim 1, characterized in that: The sampling device further includes a sampling rod (1) and a guide tube (2) located on the outer periphery of the sampling rod (1). The guide tube (2) passes through the viewing window (77). One end of the guide tube (2) located outside the box (7) is connected to the other end of the sampling rod (1) located outside the box (7) with a handle assembly (3) for driving the sampling rod (1) to extend and retract. The other end of the guide tube (2) is provided with a mounting part (21). The pressure plug (6) and the sampling mechanism (4) are located in the mounting part (21). The other end of the sampling rod (1) is provided with a pressure plug part (11) for pressing the pressure plug (6) when extending and retracting.

3. The experimental freeze dryer according to claim 2, characterized in that: The handle assembly (3) includes a first handle (31), a second handle (32), a first connecting rod (33), and a second connecting rod (34). The first handle (31) and the second handle (32) are both hinged to the guide tube (2). One end of the first connecting rod (33) is hinged to the first handle (31), and the other end of the first connecting rod (33) is hinged to the sampling rod (1). One end of the second connecting rod (34) is hinged to the second handle (32), and the other end of the second connecting rod (34) is hinged to the sampling rod (1).

4. The experimental freeze dryer according to claim 3, characterized in that: The second handle (32) is provided with a ratchet (36), and the first handle (31) is provided with a pawl (35) that can cooperate with the ratchet (36) and a latch (37) for engaging or disengaging the pawl (35) from the ratchet (36).

5. The experimental freeze dryer according to claim 4, characterized in that: The handle assembly (3) further includes a third link (38), the pawl (35) and the latch (37) are both hinged to the first handle (31), one end of the third link (38) is hinged to the latch (37), and the other end of the third link (38) is hinged to the pawl (35).

6. The experimental freeze dryer according to any one of claims 2 to 5, characterized in that: The mounting part (21) is provided with a pressure rod (61), the upper end of the pressure rod (61) is provided with a roller (63), the roller (63) abuts against the pressure plug part (11), the lower end of the pressure rod (61) is connected to the pressure plug (6), and the mounting part (21) is provided with an elastic reset member (62) for moving the pressure rod (61) upward.

7. The experimental freeze dryer according to any one of claims 2 to 5, characterized in that: The sampling mechanism (4) includes a plurality of grippers (41) arranged around the plug (6), the grippers (41) being hinged to the mounting portion (21).

8. The experimental freeze dryer according to claim 7, characterized in that: The linkage mechanism (5) includes multiple fourth links (51), one end of each of the multiple fourth links (51) is hinged to one of the multiple grippers (41), and the other end of the fourth link (51) is hinged to the pressure plug (6).

9. The experimental freeze dryer according to any one of claims 2 to 5, characterized in that: The stopper (11) is formed by bending the sampling rod (1) downwards.

10. The experimental freeze dryer according to any one of claims 1 to 5, characterized in that: The viewing window (77) is provided with a flexible support tube (71) for the sampling device to pass through and a bracket (72) for supporting the flexible support tube (71) on the side away from the housing (7). The bracket (72) is detachably connected to the viewing window (77).