Oscillating device for biological cells

Abstract

The utility model particularly relates to an oscillation device for biological cells, which comprises a top plate and a bottom plate, the top plate and the bottom plate are mutually connected and fixed through two support plates which are symmetrically arranged, a plurality of oscillation plates are slidably mounted between the two support plates, and a motor box is fixedly mounted on the upper end surface of the bottom plate. The upper end face of the motor box is fixedly provided with a rotating rod matched with the middle of each oscillation plate in an inserted mode through an output shaft of the motor box, and the periphery of the rotating rod is fixedly provided with a plurality of movable plates sequentially arranged on the lower sides of the oscillation plates; a plurality of first protruding blocks and second protruding blocks which are connected in a clamped mode are fixedly installed on the peripheries of the lower end faces of the adjacent oscillation plates and the peripheries of the upper end faces of the movable plates correspondingly, limiting sliding rails are fixedly installed on the opposite end faces of the supporting plates on the two sides correspondingly, and limiting sliding grooves in sliding fit with the limiting sliding rails on the two sides are formed in the peripheries of the oscillation plates correspondingly. Biological cells stored on the upper end face of the oscillation plate can be oscillated, and activity and functions of the cells are maintained.

Description

Technical Field

[0001] This utility model relates to the technical field of bioengineering equipment, specifically to a vibration device for biological cells. Background Technology

[0002] To increase the dissolved oxygen concentration in cell culture vessels, eliminate concentration gradients within the vessels, promote the mass transfer of nutrients and metabolites, maintain the homogeneity of the system within the vessels, and prevent cell aggregation and sedimentation, a shaking device needs to be installed in the transport equipment during the storage and long-distance transport of biological cells. This shaking device will maintain the cell activity and function.

[0003] Existing biological cell oscillation devices have relatively simple structures, mostly using electric push rods. The forward and reverse rotation of the output shaft of a reversible motor, in conjunction with the push rod, drives the storage device to move up and down, achieving the effect of oscillating biological cells. However, compared with traditional motors, reversible motors have drawbacks such as lower speed, lower torque, higher control requirements, greater maintenance difficulty, and higher cost. This makes them significantly inferior in terms of biological cell oscillation. Therefore, we propose an oscillation device for biological cells. Utility Model Content

[0004] The purpose of this invention is to provide a vibration device for biological cells to solve the problems mentioned in the background art.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a vibration device for biological cells, comprising a top plate and a bottom plate, wherein the top plate and the bottom plate are connected and fixed to each other by two symmetrically arranged support plates, and a plurality of vibration plates are slidably installed between the two support plates. A motor housing is fixedly installed on the upper surface of the bottom plate, and a rotating rod that is inserted and engaged with the middle of each vibration plate is fixedly installed on the upper surface of the motor housing through its output shaft. A plurality of movable plates arranged sequentially on the lower side of the vibration plates are fixedly installed around the rotating rods. A plurality of first protrusions and second protrusions that interlock with each other are fixedly installed on the lower surface of adjacent vibration plates and the upper surface of movable plates, respectively.

[0006] Preferably, symmetrically arranged box doors are rotatably installed between the two support plates, and the upper and lower ends of the box doors on both sides are respectively attached to the top plate and the bottom plate. Limiting slide rails are fixedly installed on the opposite end faces of the two support plates, and limiting slide grooves are opened on the periphery of each vibration plate to slide with the limiting slide rails on both sides.

[0007] Preferably, the vibrating plate has a through hole in the middle, the rotating rod is inserted into the through hole, and a plurality of first protrusions and second protrusions are equally spaced around the through hole.

[0008] Preferably, the upper surface of the oscillating plate is provided with a plurality of positioning sleeves, a support plate is slidably installed inside the positioning sleeve, and a driving sleeve that slides and cooperates with the outer periphery of the positioning sleeve is rotatably installed around the positioning sleeve.

[0009] Preferably, the inner wall of the positioning sleeve is provided with a limiting slide cavity, the outer periphery of the support plate is fixedly installed with a limiting slider that slides in cooperation with the limiting slide cavity, the outer end face of the limiting slider is fixedly installed with a driving protrusion, and the inner wall of the driving sleeve is provided with a threaded curve groove that slides in cooperation with the driving protrusion.

[0010] Compared with the prior art, the beneficial effects of this utility model are:

[0011] This is a vibration device for biological cells, which includes a motor housing and a rotating rod. Through the contact effect between the rotating second protrusion and the first protrusion at the lower end of the vibration plate, the vibration plates can be driven to move up and down within the device, thereby achieving the effect of vibration on the biological cells at the upper end of the vibration plates, improving the motility of the biological cells and preventing aggregation between the biological cells that are attached to each other.

[0012] This new type of oscillation device for biological cells, compared to existing electric actuators that use reversible motors as the main body, uses a traditional motor to achieve the effect of driving biological cells to oscillate. It also has low control requirements, low maintenance difficulty and low cost, thus improving the performance of the device.

[0013] This is a shaking device for biological cells, equipped with a positioning sleeve for storing culture flasks. By driving the sleeve and the sliding engagement between the positioning sleeve and the tray, the tray can be moved up and down, making it easy to remove the culture flask from within the positioning sleeve. Attached Figure Description

[0014] Figure 1 This is a schematic diagram of the overall external unfolded structure of this utility model;

[0015] Figure 2 This is a schematic diagram of the external structure of the door, top plate, and bottom plate of this utility model;

[0016] Figure 3 This is a schematic diagram of the external structure of the vibration plate of this utility model;

[0017] Figure 4 This is a schematic diagram of the external disassembled structure of the movable plate of this utility model;

[0018] Figure 5 This is a schematic diagram of the internal structure of the positioning sleeve of this utility model;

[0019] Figure 6 This is a schematic diagram of the internal disassembled structure of the positioning sleeve of this utility model.

[0020] In the picture:

[0021] 1. Base plate; 11. Support plate; 12. Top plate; 13. Door;

[0022] 2. Motor housing; 21. Rotating rod; 22. Vibrating plate; 23. Limiting slide rail; 24. Limiting slide groove; 25. Through hole; 26. Movable plate; 27. First protrusion; 28. Second protrusion;

[0023] 3. Positioning sleeve; 31. Support plate; 32. Drive sleeve; 33. Limiting slider; 34. Limiting slide cavity; 35. Drive protrusion; 36. Threaded curve groove. Detailed Implementation

[0024] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0025] Please see Figure 1-6 This utility model provides a technical solution: a vibration device for biological cells, including a top plate 12 and a bottom plate 1. The top plate 12 and the bottom plate 1 are connected and fixed to each other by two symmetrically arranged support plates 11. Multiple vibration plates 22 are slidably installed between the two support plates 11. A motor box 2 is fixedly installed on the upper end surface of the bottom plate 1. A rotating rod 21 that is inserted and cooperates with the middle of each vibration plate 22 is fixedly installed on the upper end surface of the motor box 2 through its output shaft. Multiple movable plates 26 are fixedly installed on the periphery of the rotating rod 21 and arranged sequentially on the lower side of the vibration plate 22. Multiple first protrusions 27 and second protrusions 28 that are interlocked are fixedly installed on the periphery of the lower end surface of the adjacent vibration plate 22 and the upper end surface of the movable plate 26, respectively.

[0026] Working principle: In use, the culture flask containing biological cells is installed on the upper end of the shaking plate 22. The motor inside the motor box 2 is started, and the rotating rod 21 is driven to rotate through its upper output shaft. This causes the movable plate 26 and its upper second protrusion 28 to rotate under the shaking plate 22. Through the continuous contact between the rotating second protrusion 28 and the fixed first protrusion 27, the shaking plates 22 can be driven to move up and down between the two support plates 11, so as to achieve the effect of shaking the biological cells on the upper end of the shaking plate 22 and avoid the aggregation of biological cells.

[0027] As a further description of the above technical solution: symmetrically arranged box doors 13 are rotatably installed between the two support plates 11, and the upper and lower ends of the box doors 13 are respectively attached to the top plate 12 and the bottom plate 1. Limiting slide rails 23 are fixedly installed on the opposite end faces of the two support plates 11. Limiting slide grooves 24 that slide with the limiting slide rails 23 are opened around the periphery of each vibration plate 22. A through hole 25 is opened in the middle of the vibration plate 22. The rotating rod 21 is inserted into the through hole 25, and multiple first protrusions 27 and second protrusions 28 are equally spaced around the through hole 25.

[0028] Specifically, the enclosure door 13 can be installed to seal the device, thereby protecting the biological cells inside the device.

[0029] By sliding between the limiting slide rail 23 and the limiting slide groove 24, the movement direction of the vibrating plate 22 can be restricted between the two support plates 11, so that the vibrating plate 22 can be driven to move up and down during the continuous contact between the second protrusion 28 and the first protrusion 27.

[0030] A through hole 25 is provided in the middle of the vibrating plate 22 to provide rotation space for the rotating rod 21, thereby avoiding interference between the rotating rod 21 and the vibrating plate 22.

[0031] As a further description of the above technical solution: multiple positioning sleeves 3 are provided on the upper end face of the vibration plate 22, a support plate 31 is slidably installed inside the positioning sleeve 3, a drive sleeve 32 is rotatably installed on the periphery of the positioning sleeve 3 and slides with the periphery of the support plate 31, a limiting slide cavity 34 is provided on the inner wall of the positioning sleeve 3, a limiting slider 33 is fixedly installed on the periphery of the support plate 31 and slides with the limiting slide cavity 34, a drive protrusion 35 is fixedly installed on the outer end face of the limiting slider 33, and a threaded curve groove 36 is provided on the inner wall of the drive sleeve 32 and slides with the drive protrusion 35.

[0032] Specifically, when installing the culture flask, the culture flask can be installed into each of the positioning sleeves 3 at the upper end of the shaking plate 22, and the lower end of the culture flask can be in contact with the upper end of the tray 31, thereby completing the installation of the biological cell product.

[0033] When removing the culture bottle from inside the positioning sleeve 3, the driving sleeve 32 can be rotated around the positioning sleeve 3. Within the positioning sleeve 3, the sliding engagement between the limiting sliding cavity 34 and the limiting slider 33 restricts the movement direction of the tray 31. This allows the rotating driving sleeve 32 to drive the tray 31 to move upward within the positioning sleeve 3 through the sliding engagement between the threaded curved groove 36 and the driving protrusion 35. This pushes the culture bottle to the upper end of the shaking plate 22, making it easier to remove the culture bottle.

[0034] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A biological cell shock device comprising a top plate (12) and a bottom plate (1), characterized in that: The top plate (12) and the bottom plate (1) are connected and fixed by two mutually symmetrical supporting plates (11), a plurality of oscillation plates (22) are slidingly installed between the two supporting plates (11), the motor box (2) is fixedly installed on the upper end surface of the bottom plate (1), the rotating rod (21) which is inserted and matched with the middle part of each oscillation plate (22) is fixedly installed on the upper end surface of the motor box (2), a plurality of movable plates (26) which are sequentially arranged on the lower side of the oscillation plate (22) are fixedly installed on the outer periphery of the rotating rod (21), and a plurality of first protrusions (27) and second protrusions (28) which are mutually clamped are respectively fixedly installed on the lower end surface of the adjacent oscillation plate (22) and the upper end surface of the movable plate (26).

2. The oscillation device for biological cells according to claim 1, characterized in that: The box door (13) which is mutually symmetrical is rotatably installed between the two supporting plates (11), and the upper and lower ends of the box door (13) on both sides are respectively attached to the top plate (12) and the bottom plate (1), the facing end surfaces of the two supporting plates (11) are respectively fixedly installed with the limiting slide rails (23), and the outer periphery of each oscillation plate (22) is provided with the limiting slide grooves (24) which are slidingly matched with the limiting slide rails (23) on both sides.

3. The biological cell shock device of claim 2, wherein: The middle part of the oscillation plate (22) is provided with the through hole (25), the rotating rod (21) is inserted into the through hole (25), and a plurality of first protrusions (27) and second protrusions (28) are equally spaced on the outer periphery of the through hole (25).

4. The oscillation device for biological cells according to claim 1, characterized in that: A plurality of positioning sleeves (3) are formed on the upper end surface of the oscillation plate (22), the supporting plate (31) is slidingly installed in the positioning sleeve (3), and the driving sleeve (32) which is slidingly matched with the outer periphery of the supporting plate (31) is rotatably installed on the outer periphery of the positioning sleeve (3).

5. The biological cell shock device of claim 4, wherein: The limiting slide cavity (34) is formed in the inner wall of the positioning sleeve (3), the limiting slide block (33) which is slidingly matched with the limiting slide cavity (34) is fixedly installed on the outer periphery of the supporting plate (31), the driving protrusion (35) is fixedly installed on the outer end surface of the limiting slide block (33), and the screw curve groove (36) which is slidingly matched with the driving protrusion (35) is formed in the inner wall of the driving sleeve (32).

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