Efficient gas-liquid separation and mixed bubble trap

By designing a liquid flow channel with a 90° bend and a liquid level sensor, a gas-liquid separation and mixing bubble trap was created, which solved the stratification problem during liquid replacement, improved replacement efficiency, and reduced the risk of bubble introduction.

CN223615432UActive Publication Date: 2025-12-02TOFFLON HAIWEI (SHANGHAI) BIOSCIENCE CO LTD
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Patent Information

Application Number
CN202423221586.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-25
Publication Date
2025-12-02
Estimated Expiration
2034-12-25

AI Technical Summary

Technical Problem

In existing chromatography equipment, liquid replacement is prone to stratification, leading to incomplete replacement.

Method used

Design a high-efficiency gas-liquid separation and mixing bubble trap, including a bottom chamber and a top chamber. The inner chamber is provided with a first liquid flow channel with a 90° bend. After the liquid enters from the inlet connector, the flow direction is changed. Combined with the liquid level sensor to monitor the liquid level height, liquid stratification is avoided.

Benefits of technology

This technology enables liquids to be separated and mixed efficiently without stratification, improving displacement efficiency and reducing the risk of bubbles being introduced into subsequent processes.

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Abstract

The utility model provides an efficient gas-liquid separation and mixed bubble trap which comprises a bottom cavity and a top cavity arranged above the bottom cavity, an inner cavity and a first liquid flow channel are arranged in the bottom cavity and the top cavity in a penetrating mode, an inlet connector and an outlet connector are arranged at the bottom of the bottom cavity, an inlet of the first liquid flow channel is connected with the inlet connector, and an outlet of the first liquid flow channel is connected with the outlet connector. The bottom of the inner cavity is connected with a second liquid flow channel inlet, and a second liquid flow channel outlet is connected with an outlet connector. An exhaust outlet is formed in the top cavity; wherein the first liquid flow channel is provided with two 90-degree break angles, so that the flowing direction of liquid is changed according to the vertical direction, and a liquid level sensor for monitoring the liquid level height is in threaded connection with the outer part of the efficient gas-liquid separation and mixed bubble trap. Belongs to the technical field of biopharmacy. And tiny bubbles generated by pressure fluctuation in the subsequent process can be effectively reduced, the structure has a better mixing effect, and the flow velocity efficiency is higher.
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Description

Technical Field

[0001] This utility model relates to a high-efficiency gas-liquid separation and mixing bubble trap, belonging to the field of biopharmaceutical technology. Background Technology

[0002] Currently, the mainstream bubble trap in chromatography equipment on the market involves making the liquid flow upward from the bottom, and then letting it flow down the wall by gravity after reaching a certain height, separating the bubbles in the process. This process is relatively slow, and when liquid replacement is performed, different liquids will separate into layers, resulting in incomplete replacement. This is an urgent problem that needs to be solved in actual production.

[0003] Therefore, there is an urgent need in the field for a highly efficient gas-liquid separation and mixing bubble trap structure that does not cause liquid stratification. Summary of the Invention

[0004] The purpose of this invention is to solve the problem in the prior art where different liquids separate into layers during liquid replacement, resulting in incomplete replacement.

[0005] To address the aforementioned problems, this invention provides a high-efficiency gas-liquid separation and mixing bubble trap, comprising a bottom chamber and a top chamber located above the bottom chamber. The bottom and top chambers are internally connected by an inner cavity and a first liquid flow channel. The bottom chamber has an inlet connector and an outlet connector at its bottom. The inlet of the first liquid flow channel is connected to the inlet connector, and the outlet is connected to the upper part of the inner cavity. The bottom of the inner cavity is connected to the inlet of a second liquid flow channel, and the outlet of the second liquid flow channel is connected to the outlet connector. The upper part of the top cavity has an exhaust outlet. The first liquid flow channel has two 90° bends, allowing the liquid to change direction vertically. An external threaded liquid level sensor for monitoring the liquid level is connected to the high-efficiency gas-liquid separation and mixing bubble trap.

[0006] Preferably, the bottom chamber is provided with a sight glass assembly for observing the liquid level.

[0007] Preferably, the bottom of the inner cavity is provided with an anti-vortex column.

[0008] Compared with the prior art, the present invention has the following beneficial effects:

[0009] 1. Compared to the original bottom inlet, where the flow rate decreased significantly after the diameter change and the liquid adhered to the wall, resulting in lower efficiency, the current inlet does not have a diameter change. By adjusting the inlet channel structure and direction, the flow rate is only slightly reduced, and two consecutive 90° turns release air from the liquid, preventing it from being carried into subsequent processes and reducing microbubbles caused by pressure fluctuations in those processes.

[0010] 2. Because the current flow direction is from bottom to top, and then from top to bottom, the lower density liquid floats on top, causing stratification and preventing some liquid from being replaced. Currently, the inlet position is being adjusted to be closer to the top of the inner cavity. Figure 6 When the liquid level is close to that of the liquid during use, the liquid enters the interior and flows from top to bottom without causing stratification. Moreover, when entering the inner cavity, it is closer to the top. After entering the bubble trap, the bubbles are directly discharged to the top and will not flow down to the next process. The replacement can be completed quickly at a high flow rate. Attached Figure Description

[0011] Figure 1 This is a front view of the high-efficiency gas-liquid separation and mixing bubble trap of this utility model;

[0012] Figure 2 This is a rear view of the high-efficiency gas-liquid separation and mixing bubble trap of this utility model;

[0013] Figure 3 Cross-sectional view of the present invention: high-efficiency gas-liquid separation and mixing bubble trap Figure 1 ;

[0014] Figure 4 Cross-sectional view of the present invention: high-efficiency gas-liquid separation and mixing bubble trap Figure 2 ;

[0015] Figure 5 Cross-sectional view of the present invention: high-efficiency gas-liquid separation and mixing bubble trap Figure 3 ;

[0016] Figure 6 Cross-sectional view of the present invention: high-efficiency gas-liquid separation and mixing bubble trap Figure 4 ;

[0017] Figure 7 This is a schematic diagram of the bottom cavity structure of the high-efficiency gas-liquid separation and mixing bubble trap of this utility model;

[0018] Reference numerals: 1. Bottom chamber; 2. Top chamber; 3. Exhaust outlet; 4. Sight glass assembly; 5. Outlet connector; 6. Inlet connector; 7. First liquid flow channel; 8. Second liquid flow channel; 9. Inner cavity; 10. Liquid level sensor. Detailed Implementation

[0019] To make this utility model more apparent and understandable, preferred embodiments are described in detail below with reference to the accompanying drawings:

[0020] like Figure 1-4As shown, this utility model provides a high-efficiency gas-liquid separation and mixing bubble trap. It includes a bottom chamber 1 and a top chamber 2 located above the bottom chamber. An inner cavity 9 and a first liquid flow channel 7 are connected through the bottom chamber 1 and the top chamber 2. The bottom chamber 1 has an inlet connector 6 and an outlet connector 5 at its bottom. The inlet of the first liquid flow channel 7 is connected to the inlet connector 6, and the outlet is connected to the upper part of the inner cavity 9. The bottom of the inner cavity 9 is connected to the inlet of a second liquid flow channel 8, and the outlet of the second liquid flow channel 8 is connected to the outlet connector 5. The top chamber 2 has an exhaust outlet 3 at its upper part. The first liquid flow channel 7 has two 90° bends, allowing the liquid to change its flow direction vertically. A liquid level sensor 10 for monitoring the liquid level is externally threaded onto the high-efficiency gas-liquid separation and mixing bubble trap.

[0021] Example 1

[0022] A high-efficiency gas-liquid separation and mixing bubble trap includes a bottom chamber 1 and a top chamber 2 located above the bottom chamber. A first liquid flow channel 7 has two 90° bends inside. The bottom of the first liquid flow channel 7 is connected to an inlet connector 6. The inlet of a second liquid flow channel 8 is connected to an inner cavity 9. The bottom of the inner cavity 9 has an outlet connected to an outlet connector 5. An exhaust outlet 3 is provided at the top of the top chamber. A sight glass assembly 4 for observing the liquid level is provided on the side of the bottom chamber.

[0023] This invention features a design where the liquid is tangent to the inner wall at a high point. Liquid enters the liquid flow channel 7 through the inlet connector 6 of the bottom chamber 1 and exits at the high point. The gas and liquid phases separate directly at the high point of the inlet, with bubbles rising directly to the surface and exiting from above. The liquid flows downwards under gravity and is tangentially mixed by the front-end power. The liquid level in the bubble trap is adjusted to be above the inlet by a leveling device. The replacement liquid begins from the top, without the large diameter change that previously reduced the flow rate, thus maintaining the flow velocity. The replacement process effectively mixes the liquid, resulting in a significant improvement over current methods.

[0024] The above description is merely a preferred embodiment of this utility model and is not intended to limit this utility model in any form or substance. It should be noted that those skilled in the art can make various improvements and additions without departing from this utility model, and these improvements and additions should also be considered within the protection scope of this utility model. Any modifications, alterations, and equivalent changes made by those skilled in the art without departing from the spirit and scope of this utility model using the disclosed technical content are equivalent embodiments of this utility model. Furthermore, any modifications, alterations, and evolutions made to the above embodiments based on the essential technology of this utility model are still within the scope of the technical solution of this utility model.

Claims

1. A highly efficient gas-liquid separation and mixing bubble trap, characterized in that, It includes a bottom chamber and a top chamber located above the bottom chamber. The bottom chamber and the top chamber are connected by an inner cavity and a first liquid flow channel. The bottom chamber has an inlet connector and an outlet connector at its bottom. The inlet of the first liquid flow channel is connected to the inlet connector, and the outlet is connected to the upper part of the inner cavity. The bottom of the inner cavity is connected to the inlet of the second liquid flow channel, and the outlet of the second liquid flow channel is connected to the outlet connector. The top chamber has an exhaust outlet. The first liquid flow channel has two 90° bends, so that the liquid changes its flow direction vertically. The high-efficiency gas-liquid separation and mixing bubble trap is externally threaded with a liquid level sensor for monitoring the liquid level.

2. The high-efficiency gas-liquid separation and mixing bubble trap as described in claim 1, characterized in that, The bottom chamber is equipped with a sight glass assembly for observing the liquid level.

3. The high-efficiency gas-liquid separation and mixing bubble trap as described in claim 1, characterized in that, The bottom of the inner cavity is provided with an anti-vortex column.