Gel granulation equipment

Abstract

The utility model relates to gel granulation equipment which comprises a cutting assembly and a screening assembly, the cutting assembly comprises a granulation cylinder and a cutter arranged in the granulation cylinder, and the cutter is used for cutting gel fed into the granulation cylinder; the screening assembly comprises a screen and an opening and closing plate, the cutter, the opening and closing plate and the screen are sequentially arranged at intervals in the gravity direction, the opening and closing plate is used for bearing colloidal particles cut by the cutter, and when the bearing weight reaches a preset value, the opening and closing plate is opened, so that the colloidal particles borne by the opening and closing plate fall on the screen. The cutter is arranged in the granulation cylinder, and when gel is fed into the granulation cylinder, the cutter can start to work to cut the gel in the granulation cylinder. The cutter, the opening and closing plate and the screen are arranged in the gravity direction, gel cut by the cutter can directly fall onto the opening and closing plate under the action of gravity, and when the bearing weight of the opening and closing plate reaches a preset value, the opening and closing plate is opened, so that the gel borne by the opening and closing plate falls into the screen, secondary cutting is conducted through the screen, and the cutting procedure of the gel is completed.

Description

Technical Field

[0001] This application relates to the field of biopharmaceutical manufacturing equipment technology, and in particular to a gel granulation device. Background Technology

[0002] Hyaluronic acid is a natural macromolecule widely found in the skin and subcutaneous tissue. It has adhesive properties and can tightly bind collagen and elastin fibers. Cross-linked hyaluronic acid gel can form a covalent cross-linked network between molecules, increasing its mechanical strength and extending its degradation time, thus expanding its application range and making it an effective clinical soft tissue filler. Currently, most injectable hyaluronic acid gels used clinically are in microparticle form, meaning they are prepared into gel microparticles of a specific size using equipment. However, existing equipment often produces gel particles with poor uniformity, resulting in particle sizes that do not meet pre-set requirements. Utility Model Content

[0003] Therefore, it is necessary to provide a gel granulation device to address the aforementioned gel particle size problem.

[0004] The gel granulation equipment includes:

[0005] A cutting assembly includes a granulation cylinder and a cutter disposed within the granulation cylinder, the cutter being used to cut the gel fed into the granulation cylinder;

[0006] The screening assembly includes a screen and a hinged plate. The cutter, the hinged plate, and the screen are arranged in sequence at intervals along the direction of gravity. The hinged plate is used to carry the rubber particles cut by the cutter. When the load reaches a preset value, the hinged plate opens so that the rubber particles carried by the hinged plate fall onto the screen.

[0007] In one embodiment, the opening and closing plate includes a first plate and a second plate, with one end of the first plate and the second plate facing away from each other being rotatably connected to the granulation cylinder, and the first plate and the second plate being rotatable to achieve opening and closing.

[0008] In one embodiment, the screening assembly further includes a drive member for driving the first plate and the second plate to move up and down synchronously when the first plate and the second plate are closed.

[0009] In one embodiment, a transmission plate is connected to the opposite ends of the first plate and the second plate;

[0010] The granulation cylinder is provided with sliding grooves arranged along a first direction and extending along the direction of gravity, wherein the first direction is perpendicular to the lifting direction of the opening and closing plate, the sliding grooves and the transmission plates correspond one-to-one, and the transmission plates pass through the corresponding sliding grooves and are respectively connected to the first plate and the second plate;

[0011] The driving components are respectively disposed outside the granulation cylinder and connected to the corresponding transmission plate. The driving components can drive the corresponding transmission plate to slide in the groove in the vertical direction, so that the first plate and the second plate can move up and down when they are closed.

[0012] In one embodiment, the cutting tool includes a mounting portion and a plurality of blades, the plurality of blades being arranged in a circumferential spiral around the mounting portion.

[0013] In one embodiment, a group of cutting units is formed by multiple blades arranged in a circumferential spiral around the mounting portion. Multiple groups of cutting units are provided, and the multiple groups of cutting units are arranged along the axial direction of the mounting portion.

[0014] In one embodiment, the mounting portion has a virtual plane tangent to its outer peripheral surface, and the blade has a cutting surface at one end away from the mounting portion, with an angle between the cutting surface and the virtual plane.

[0015] In one embodiment, the screening assembly further includes a pressure sensor for detecting the pressure value applied to the opening and closing plate.

[0016] In one embodiment, a material transfer assembly is also included, the material transfer assembly including a feeding cylinder and a drive shaft located within the feeding cylinder, the drive shaft being provided with a transmission element for conveying gel toward the granulation cylinder, and the cutter being mounted on the end of the drive shaft away from the feeding cylinder.

[0017] In one embodiment, the cutting tool and the drive shaft are connected by a key to maintain the same rotational speed between the cutting tool and the drive shaft.

[0018] The aforementioned gel granulation equipment includes a cutting tool inside the granulation cylinder. When gel is fed into the cylinder, the tool begins granulation. The cutting tool, opening / closing plate, and screen are arranged along the direction of gravity. The gel cut by the cutting tool falls directly onto the opening / closing plate under gravity. When the load on the opening / closing plate reaches a preset value, the plate opens, allowing the gel to fall onto the screen. A drive unit then presses the opening / closing plate down, completing a secondary cut and thus finishing the gel cutting process. This application, by setting up a cutting component and a screening component, cuts first and then screens, resulting in a more uniform gel particle size after passing through the screening component.

[0019] Compared with the prior art, this application has the following beneficial effects:

[0020] 1. To address the problems of gel degradation due to gel frictional heating, unstable pressure due to mutual compression between gels and gravity, and uneven particle size caused by current homogenization, grinding, and simple sieve extrusion granulation methods, this application provides a highly efficient granulation device for obtaining uniform and controllable particle size. By setting the crushing blade and opening and closing plate, compared with the commonly used granulation devices, the process of this application has higher continuity. The obtained particle size is controlled according to the sieve mesh number and the feeding and granulation speed, which is more uniform and controllable, thus making up for the defects of current common granulation methods.

[0021] 2. The gel prepared in this application is not easily degraded by keeping the cutting tool and the drive shaft at the same rotation speed. Attached Figure Description

[0022] Figure 1 This is a schematic diagram of the structure of the gel granulation equipment provided in the embodiments of this application.

[0023] Figure 2 This is a schematic diagram of a granulation cylinder provided in an embodiment of this application, which has a groove and a driving component.

[0024] Figure 3 This is a schematic diagram of the opening and closing plate provided in an embodiment of this application.

[0025] Figure 4 This is a first-view structural schematic diagram of the cutting tool provided in an embodiment of this application.

[0026] Figure 5 This is a structural schematic diagram of the cutting tool provided in an embodiment of this application from a second perspective.

[0027] Figure label:

[0028] 100. Material transfer assembly; 110. Feeding cylinder; 120. Drive shaft; 130. Transmission component;

[0029] 200. Cutting assembly; 210. Granulation cylinder; 220. Cutting tool; 221. Blade; 222. Mounting part; 223. Virtual plane; 224. Cutting surface; 230. Groove;

[0030] 300. Screening assembly; 310. Screen; 320. Opening / closing plate; 321. First plate; 322. Second plate; 330. Driving component; 340. Transmission plate; 350. Pressure sensor;

[0031] 400. Outer shell; 410. Inlet; 420. Outlet;

[0032] 500. Feeding bucket. Detailed Implementation

[0033] To make the above-mentioned objectives, features, and advantages of this application more apparent and understandable, the specific embodiments of this application are described in detail below with reference to the accompanying drawings. Many specific details are set forth in the following description to provide a thorough understanding of this application. However, this application can be implemented in many other ways different from those described herein, and those skilled in the art can make similar modifications without departing from the spirit of this application. Therefore, this application is not limited to the specific embodiments disclosed below.

[0034] In the description of this application, it should be understood that if terms such as "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential" appear, these terms indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this application.

[0035] Furthermore, where the terms "first" and "second" appear, these terms are for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined with "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this application, where the term "multiple" appears, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly specified.

[0036] In this application, unless otherwise expressly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise expressly limited. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.

[0037] In this application, unless otherwise expressly specified and limited, the use of descriptions such as "above" or "below" the second feature indicates that the first and second features are in direct contact or indirect contact via an intermediate medium. Furthermore, "above," "on top of," and "over" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. Similarly, "below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.

[0038] It should be noted that if an element is referred to as being "fixed to" or "set on" another element, it can be directly on the other element or there may be an intervening element. If an element is considered to be "connected to" another element, it can be directly connected to the other element or there may be an intervening element. If so, the terms "vertical," "horizontal," "upper," "lower," "left," "right," and similar expressions used in this application are for illustrative purposes only and do not represent the only possible implementation.

[0039] This application provides a gel granulation device, such as... Figure 1 and Figure 2 As shown, the gel granulation equipment includes a cutting component 200 and a screening component 300. The cutting component 200 includes a granulation cylinder 210 and a cutter 220 disposed inside the granulation cylinder 210. The cutter 220 is used to cut the gel fed into the granulation cylinder 210. The screening component 300 includes a screen 310 and an opening and closing plate 320. The cutter 220, the opening and closing plate 320, and the screen 310 are arranged in sequence at intervals along the direction of gravity. The opening and closing plate 320 is used to carry the gel particles cut by the cutter 220. When the weight carried reaches a preset value, the opening and closing plate 320 opens so that the gel particles carried by the opening and closing plate 320 fall onto the screen 310.

[0040] The aforementioned gel granulation equipment includes a cutter 220 inside the granulation cylinder 210. When gel is fed into the granulation cylinder 210, the cutter 220 begins to cut the gel. The cutter 220, the opening / closing plate 320, and the screen 310 are arranged along the direction of gravity. The gel cut by the cutter 220 falls directly onto the opening / closing plate 320 under gravity. When the load on the opening / closing plate 320 reaches a preset value, the plate opens, allowing the gel to fall onto the screen 310 for secondary cutting, thus completing the gel cutting process. This application, by setting up a cutting component 200 and a screening component 300, cuts first and then screens, resulting in a more uniform gel particle size after passing through the screening component 300. Moreover, the opening and closing plate 320 will open when the weight of the gel it carries reaches the preset value. The opening and closing plate 320 and the screen 310 work together and are controlled by the program. After the previous screen cut is completed, the opening and closing plate 320 will open again to transport the next batch of gel to the screen 310. The opening and closing plate 320 avoids the situation where too much gel accumulates on the screen, which would cause the gel particles cut by the screen 310 to be unstable, and further makes the particle size after cutting more uniform.

[0041] Specifically, such as Figure 1 and Figure 3 As shown, the opening and closing plate 320 includes a first plate 321 and a second plate 322. The ends of the first plate 321 and the second plate 322 that are opposite to each other are rotatably connected to the granulation cylinder 210. The first plate 321 and the second plate 322 can rotate to achieve opening and closing. By rotating the end of the first plate 321 opposite to the second plate 322 to the inner wall of the granulation cylinder 210, and the end of the second plate 322 opposite to the first plate 321 to the inner wall of the granulation cylinder 210, when the weight of the gel carried by the opening and closing plate 320 reaches a preset value, the first plate 321 and the second plate 322 rotate relative to each other, thereby opening the first plate 321 and the second plate 322. The gel cut by the cutter 220 passes through the gap formed by the opening of the first plate 321 and the second plate 322 and falls onto the screen 310. After the gel on the opening and closing plate 320 has completely fallen onto the screen 310, the first plate 321 and the second plate 322 rotate again to close.

[0042] Specifically, such as Figure 1 As shown, the screening assembly 300 also includes a driving member 330, which is used to drive the first plate 321 and the second plate 322 to move up and down when the first plate 321 and the second plate 322 are closed. After the first plate 321 and the second plate 322 are closed, the driving member 330 drives the first plate 321 and the second plate 322 to press against the screen 310 along the direction of gravity, thereby squeezing the gel carried on the screen 310, so that the gel is cut again under the pressure of the first plate 321 and the second plate 322. After the gel on the screen 310 is cut, the driving member 330 drives the first plate 321 and the second plate 322 to move up and down as follows. Figure 1 The vertical upward movement, as seen from the perspective, allows it to return to its original position.

[0043] Specifically, such as Figure 1 and Figure 2 As shown, the first plate 321 and the second plate 322 are each connected to a transmission plate 340 at opposite ends; the granulation cylinder 210 is provided with a slide groove 230 arranged along a first direction and extending along the direction of gravity, wherein the first direction is perpendicular to the lifting direction of the opening and closing plate 320, the slide groove 230 and the transmission plate 340 correspond one-to-one, the transmission plate 340 passes through the corresponding slide groove 230 and is respectively connected to the first plate 321 and the second plate 322; the driving member 330 is respectively disposed outside the granulation cylinder 210 and connected to the corresponding transmission plate 340, the driving member 330 can drive the corresponding transmission plate 340 to slide in the slide groove 230 in the vertical direction, so that the first plate 321 and the second plate 322 perform lifting and lowering movements when they are closed. By setting a transmission plate 340, one end of the transmission plate 340 is set outside the granulation cylinder 210 and connected to the output end of the drive member 330, and the other end passes through the slide groove 230 and extends into the granulation cylinder 210 and is respectively connected to the first plate 321 and the second plate 322. The drive member 330 drives the corresponding transmission plate 340 to slide along the slide groove 230, thereby causing the first plate 321 and the second plate 322 to move up and down in the granulation cylinder 210.

[0044] It should be noted that the transmission plate 340 includes two parts, one part is disposed outside the granulation cylinder 210, and the other part extends through the slide groove 230 into the granulation cylinder 210 and is connected to the first plate 321 or the second plate 322.

[0045] It should be noted that the chute 230 has a through-hole structure, connecting the space inside the granulation cylinder 210 with the outside space.

[0046] More specifically, in this embodiment, two transmission plates 340 are provided, which are respectively connected to the first plate 321 and the second plate 322. Two sliding grooves 230 are provided, which are arranged along the first direction, and the two sliding grooves 230 correspond one-to-one with the two transmission plates 340. Two driving members 330 are provided, and the output ends of the two driving members 330 are connected one-to-one with the transmission plates 340.

[0047] More specifically, in this embodiment, the driving component 330 is a cylinder, and the piston rod of the cylinder is connected to the corresponding transmission plate 340.

[0048] In other embodiments, the drive component 330 is a robotic arm connected to the transmission plate 340. The robotic arm drives the transmission plate 340 to move downward, thereby pressing the first plate 321 and the second plate 322 against the screen 310. Alternatively, the drive component 330 is a rotary motor, and the output shaft of the rotary motor is connected to the transmission plate 340 through a lead screw structure.

[0049] Furthermore, the screening assembly 300 also includes a spring disposed outside the granulation cylinder 210. One end of the spring is connected to the transmission plate 340, and the other end is connected to the outer wall of the granulation cylinder 210. When the first plate 321 and the second plate 322 press against the screen 310, the spring is compressed. When there is no external force, the spring can push the transmission plate 340 to move in the vertically upward direction through its own elastic force, thereby driving the first plate 321 and the second plate 322 to reset.

[0050] Furthermore, such as Figure 1 As shown, the screening assembly 300 also includes a pressure sensor 350, which is used to detect the pressure value on the opening and closing plate 320. The rubber particles cut by the blade 220 can fall onto the opening and closing plate 320. The pressure sensor 350 detects the pressure value of the opening and closing plate 320, that is, the weight value of the rubber particles carried by the opening and closing plate 320. By comparing the pressure value with a preset value, it is determined whether the opening and closing plate 320 needs to be opened based on the comparison result.

[0051] Specifically, the pressure sensor 350 is mounted on the opening / closing plate 320 or the transmission plate 340.

[0052] It should be noted that the specific position of the pressure sensor 350 on the opening / closing plate 320, or on the transmission plate 340, is adjusted according to the actual operation. For example, the pressure sensor 350 may be located inside the pelletizing cylinder 210 and installed on the lower end face of the opening / closing plate 320, or the pressure sensor 350 may be located outside the pelletizing cylinder 210 and installed on the transmission plate 340.

[0053] Specifically, the gel granulation equipment includes a controller, a pressure sensor 350, and an opening / closing plate 320 electrically connected. The pressure sensor 350 transmits the detected pressure signal to the controller. The controller compares the pressure value with a preset value. If the pressure value is greater than or equal to the preset value, the controller controls the first plate 321 and the second plate 322 to rotate relative to each other, thereby opening the opening / closing plate 320. After the gel on the opening / closing plate 320 falls onto the screen 310, the controller then controls the first plate 321 and the second plate 322 to rotate relative to each other, thereby closing the opening / closing plate 320.

[0054] Furthermore, the screen 310 is installed on the granulation cylinder 210 in two ways: one is that the screen 310 is set inside the granulation cylinder 210 and fixedly connected to the cylinder wall of the granulation cylinder 210; the other is as follows... Figure 1 As shown, the screen 310 is partially located outside the granulation cylinder 210, and partially passes through the granulation cylinder 210 and extends into the granulation cylinder 210. Compared to the first installation structure, the screen 310 installed in the second installation structure is a pull-out screen, which facilitates the replacement of the screen 310.

[0055] Furthermore, such as Figure 1 As shown, the gel granulation equipment also includes a material transfer assembly 100, which includes a feeding cylinder 110 and a drive shaft 120 located inside the feeding cylinder 110. The drive shaft 120 is provided with a transmission component 130 for conveying gel toward the granulation cylinder 210. A cutter 220 is installed at the end of the drive shaft 120 away from the feeding cylinder 110. The drive shaft 120 is provided with a transmission component 130. When the drive shaft 120 rotates, it drives the transmission component 130 to rotate, so as to send the gel to be cut in the feeding cylinder 110 into the granulation cylinder 210, so as to wait for the cutter 220 in the granulation cylinder 210 to cut it. The cutting tool 220 is also connected to the transmission shaft 120. That is, while the transmission shaft 120 drives the transmission component 130 to rotate, the cutting tool 220 also rotates synchronously. This application connects the transmission shaft 120, the transmission component 130 and the cutting tool 220 into one unit. By driving the transmission component 130 and the cutting tool 220 to rotate synchronously through the transmission shaft 120, the feeding rate and the cutting rate are controlled to be consistent, reducing the generation of heat and making it easier to control the particle size during cutting.

[0056] Specifically, such as Figure 1 As shown, the cutter 220 and the drive shaft 120 are connected by a key to maintain the same rotational speed. Connecting the cutter 220 and the drive shaft 120 by the key fixes them circumferentially, allowing the drive shaft 120 to drive the cutter 220 to rotate. Furthermore, because the transmission component 130 is also fixed to the drive shaft 120, the drive shaft 120, the cutter 220, and the transmission component 130 maintain the same rotational speed, thereby controlling the feed rate and cutting rate to be consistent.

[0057] Furthermore, such as Figure 1 , Figure 4 as well as Figure 5 As shown, the tool 220 and the drive shaft 120 are connected by a flat key. The flat key includes a groove and a protrusion, one of which is provided on the tool 220 and the other is provided on the drive shaft 120. The protrusion can engage with the groove to achieve the connection between the tool 220 and the drive shaft 120.

[0058] In some embodiments, a groove is provided on the drive shaft 120 and a protrusion is provided on the cutter 220.

[0059] In this embodiment, as Figure 4 and Figure 5 As shown, a groove is provided on the tool 220 and a protrusion is provided on the drive shaft 120. The tool 220 is sleeved on the drive shaft 120, and the protrusion is engaged with the groove, thereby achieving circumferential fixation of the tool 220 and the drive shaft 120.

[0060] More specifically, the groove extends axially along the mounting portion 222, and the protrusion extends axially along the drive shaft 120.

[0061] In other embodiments, the tool 220 and the drive shaft 120 may also be connected by a semi-circular key, a wedge key, or a spline.

[0062] Specifically, such as Figure 1 As shown, the feeding cylinder 110 has an inlet and an outlet, and the granulation cylinder 210 has an inlet and an outlet. The inlet of the granulation cylinder 210 is connected to the outlet of the feeding cylinder 110. The cutter 220, the opening and closing plate 320, the screen 310, and the outlet of the granulation cylinder 210 are arranged along the direction of gravity. The gel to be cut can enter the feeding cylinder 110 through the inlet of the feeding cylinder 110. Driven by the transmission component 130, the gel to be cut in the feeding cylinder 110 can enter the granulation cylinder 210 through the outlet of the feeding cylinder 110. The gel cut by the cutter 220 and the screen 310 can be discharged through the outlet of the granulation cylinder 210.

[0063] More specifically, such as Figure 1 As shown, the end of the drive shaft 120 passes through the inlet of the granulation cylinder 210 and extends into the granulation cylinder 210, abutting against the cylinder wall of the granulation cylinder 210. A cutter 220 is installed on the end of the drive shaft 120 away from the feeding cylinder 110, that is, a cutter 220 is installed in the area where the drive shaft 120 extends into the granulation cylinder 210.

[0064] Specifically, such as Figure 1 As shown, in this embodiment, the transmission member 130 is spirally arranged around the outside of the transmission shaft 120. The transmission member 130 is spirally wound around the transmission shaft 120, and the rotation of the transmission shaft 120 drives the spiral transmission member 130 to rotate, thereby causing the gel in the feeding cylinder 110 to move along the axial direction of the transmission shaft 120 into the granulation cylinder 210.

[0065] In other embodiments, the transmission component 130 is a push plate threaded to the transmission shaft 120. The rotation of the transmission shaft 120 drives the push plate to move along the axial direction of the transmission shaft 120, thereby pushing the gel in the feeding cylinder 110 to move along the axial direction of the transmission shaft 120 into the granulation cylinder 210.

[0066] It is understandable that the transmission component 130 can have various configurations, as long as it can convert the rotation of the transmission shaft 120 into movement, thereby pushing the gel in the feeding cylinder 110 to move along the axial direction of the transmission shaft 120.

[0067] Furthermore, such as Figure 1 , Figure 4 as well as Figure 5As shown, the cutting tool 220 includes a mounting part 222 and multiple blades 221, which are arranged spirally around the mounting part 222. By providing the mounting part 222, the mounting part 222 is connected to the drive shaft 120 by a key. The multiple blades 221 are spirally arranged around the mounting part 222. The drive shaft 120 drives the mounting part 222 to rotate, thereby driving the multiple blades 221 to perform spiral cutting.

[0068] Specifically, such as Figure 1 , Figure 4 as well as Figure 5 As shown, a groove is provided on the mounting part 222 to engage with the protrusion of the drive shaft 120.

[0069] Specifically, such as Figure 1 , Figure 4 as well as Figure 5 As shown, multiple blades 221 arranged in a circumferential spiral around the mounting portion 222 constitute a cutting unit. Multiple cutting units are provided, and these units are arranged axially along the mounting portion 222. With multiple cutting units, the drive shaft 120 drives the mounting portion 222 to rotate, thereby causing the multiple cutting units to cut synchronously, improving cutting efficiency.

[0070] Specifically, such as Figure 1 , Figure 4 as well as Figure 5 As shown, the mounting portion 222 has a virtual plane 223 tangent to its outer peripheral surface, and the end of the blade 221 facing away from the mounting portion 222 has a cutting surface 224, with an angle between the cutting surface 224 and the virtual plane 223. By setting the cutting surface 224 of the blade 221 at an angle to the virtual plane 223, the mounting angle of the blade 221 on the mounting portion 222 is defined, thereby defining the cutting angle of the tool 220.

[0071] More specifically, in this embodiment, the angle between the cutting surface 224 and the virtual plane 223 is an acute angle.

[0072] More specifically, the feeding cylinder 110 is cylindrical, and its inner diameter, the maximum inner diameter of the discharge area of ​​the granulation cylinder 210, and the diameter of the cutter 220 are all equal. The discharge area of ​​the granulation cylinder 210 refers to the area through which the gel flows after being cut by the cutter 220. Because the drive shaft 120 can synchronously drive the drive component 130 and the cutter 220 to rotate, the feeding rate and cutting rate are adjusted. By limiting the inner diameter of the feeding cylinder 110, the maximum inner diameter of the discharge area of ​​the granulation cylinder 210, and the diameter of the cutter 220 to be equal, the material transfer component 100 and the cutting component 200 can cooperate to cut all the gel in the granulation cylinder 210, so that the gel can be fully and efficiently pulverized.

[0073] Further, please return to the reference. Figure 1 The gel granulation equipment also includes a housing 400, within which a material transfer component 100, a cutting component 200, and a screening component 300 are all housed. The housing 400 has an inlet 410 and an outlet 420. The inlet 410 is connected to the inlet of the feeding cylinder 110, and the outlet of the granulation cylinder 210 is connected to the outlet 420. By housing the material transfer component 100, the cutting component 200, and the screening component 300 are all housed within the housing 400, thus protecting these components and preventing external dust or water droplets from falling into them and affecting the preparation of gel particles. A feed inlet 410 is provided on the outer shell 400. The gel to be cut enters the feed cylinder 110 through the feed inlet 410 and the inlet of the feed cylinder 110 in sequence. The gel cut by the screen 310 flows out of the outer shell 400 through the outlet 420 and the outlet 420 in sequence.

[0074] Specifically, such as Figure 1 As shown, the gel granulation equipment also includes a feed tank 500, the cavity of which is connected to the feeding cylinder 110. By setting up the feed tank 500, the gel to be cut can flow into the feeding cylinder 110 sequentially through the outlet of the feed tank 500, the inlet 410, and the inlet of the feeding cylinder 110.

[0075] More specifically, such as Figure 1 As shown, the outlet of the feed tank 500 has a large end and a small end. The large end is connected to the cavity of the feed tank 500, and the small end passes through the feed port 410 and the inlet of the feed cylinder 110 in sequence and is connected to the cavity of the feed cylinder 110, thereby preventing the gel to be cut in the feed tank 500 from flowing into the outer shell 400.

[0076] Specifically, the gel granulation equipment also includes a collection tank located outside the outer casing 400, with the cavity of the collection tank connected to the discharge port 420. By setting up the collection tank, the gel, after being cut again by the screen 310, flows sequentially through the outlet of the granulation cylinder 210 and the discharge port 420 into the collection tank for collection.

[0077] In summary, the gel granulation equipment of this application has the following beneficial effects:

[0078] 1. Existing gel pulverization methods mostly involve stirring and homogenization. These methods disrupt the already cross-linked molecular structure of sodium hyaluronate during pulverization, and the friction between gel particles generates heat, leading to varying degrees of gel decomposition. The gel granulation equipment of this application maintains the same rotation speed between the material transfer assembly 100 and the cutting assembly 200. The drive shaft 120 of the material transfer assembly 100 drives the cutter 220 to rotate. Maintaining the same rotation speed between the material feeder 130 and the cutter 220 reduces heat generation and maintains gel stability, facilitating subsequent cutting. Furthermore, by arranging multiple blades 221 on the mounting section 222, the inner diameter of the feeding cylinder 110, the maximum inner diameter of the discharge area of ​​the granulation cylinder 210, and the diameter of the cutter 220 are all equal, allowing for thorough and efficient gel pulverization.

[0079] 2. Existing granulation methods using a sieve 310 for cutting, while controlling particle size range through the sieve 310, suffer from the influence of gravity, resulting in gel particles larger than intended or re-aggregating after passing through the sieve 310. This application addresses this by using a cladding plate 320 to first open and then press, preventing excessive gel aggregation on the sieve 310 and thus avoiding pressure instability, resulting in more uniform particle size.

[0080] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0081] The above embodiments merely illustrate several implementation methods of this application, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the patent application. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this application, and these all fall within the protection scope of this application. Therefore, the protection scope of this patent application should be determined by the appended claims.

Claims

1. A gel granulation device, characterized in that, The gel granulation equipment includes: The cutting assembly (200) includes a granulation cylinder (210) and a cutter (220) disposed within the granulation cylinder (210), the cutter (220) being used to cut the gel fed into the granulation cylinder (210); The screening assembly (300) includes a screen (310) and a hinged plate (320). The cutter (220), the hinged plate (320), and the screen (310) are arranged in sequence at intervals along the direction of gravity. The hinged plate (320) is used to carry the rubber particles cut by the cutter (220). When the load reaches a preset value, the hinged plate (320) opens so that the rubber particles carried by the hinged plate (320) fall onto the screen (310).

2. The gel granulation equipment according to claim 1, characterized in that, The opening and closing plate (320) includes a first plate (321) and a second plate (322). The ends of the first plate (321) and the second plate (322) that are opposite to each other are rotatably connected to the granulation cylinder (210). The first plate (321) and the second plate (322) can rotate to achieve opening and closing.

3. The gel granulation equipment according to claim 2, characterized in that, The screening assembly (300) further includes a drive member (330), which is used to drive the first plate (321) and the second plate (322) to move up and down synchronously when the first plate (321) and the second plate (322) are closed.

4. The gel granulation equipment according to claim 3, characterized in that, The first plate (321) and the second plate (322) are each connected to a transmission plate (340) at opposite ends; The granulation cylinder (210) is provided with a sluice (230) arranged along a first direction and extending along the direction of gravity, wherein the first direction is perpendicular to the lifting direction of the opening and closing plate (320), the sluice (230) and the transmission plate (340) correspond one-to-one, the transmission plate (340) passes through the corresponding sluice (230) and is respectively connected to the first plate (321) and the second plate (322); The driving components (330) are respectively disposed outside the granulation cylinder (210) and connected to the corresponding transmission plate (340). The driving components (330) can drive the corresponding transmission plate (340) to slide in the slide groove (230) in the vertical direction so that the first plate (321) and the second plate (322) can move up and down when they are closed.

5. The gel granulation equipment according to claim 1, characterized in that, The cutting tool (220) includes a mounting portion (222) and a plurality of blades (221), the plurality of blades (221) being arranged in a circumferential spiral around the mounting portion (222).

6. The gel granulation equipment according to claim 5, characterized in that, A cutting unit is formed by a plurality of blades (221) arranged in a circumferential spiral around the mounting portion (222). Multiple cutting units are provided, and the multiple cutting units are arranged along the axial direction of the mounting portion (222).

7. The gel granulation equipment according to claim 5, characterized in that, The mounting part (222) has a virtual plane (223) tangent to its outer peripheral surface, and the blade (221) has a cutting surface (224) at one end away from the mounting part (222), and there is an angle between the cutting surface (224) and the virtual plane (223).

8. The gel granulation equipment according to claim 1, characterized in that, The screening assembly (300) also includes a pressure sensor (350) for detecting the pressure value applied to the opening and closing plate (320).

9. The gel granulation equipment according to claim 1, characterized in that, It also includes a material transfer assembly (100), which includes a feeding cylinder (110) and a drive shaft (120) located inside the feeding cylinder (110). The drive shaft (120) is provided with a transmission element (130) for conveying gel toward the granulation cylinder (210). The cutter (220) is installed at the end of the drive shaft (120) away from the feeding cylinder (110).

10. The gel granulation equipment according to claim 9, characterized in that, The cutting tool (220) and the drive shaft (120) are connected by a key to keep the cutting tool (220) and the drive shaft (120) rotating at the same speed.

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