Dyeing kit and section dyeing equipment

Abstract

The utility model provides a staining kit and section staining equipment, the staining kit comprises a box body, an upper cover and a sealing plate, the box body is provided with an inner cavity with an upper opening for loading a staining reagent, the box body is connected with a sealing film, the sealing film seals the inner cavity, the upper cover is connected to the upper end of the box body and covers the opening of the inner cavity, and the sealing plate is connected with the upper cover. An inner cavity is formed in the upper cover, the upper cover is provided with an insertion groove communicated with the inner cavity so that a glass slide can enter the insertion groove, a sealing plate is connected to the upper cover and provided with a reset mechanism, the insertion groove is sealed by the sealing plate under the action of the reset mechanism, and the insertion groove can be opened when the glass slide is inserted into the insertion groove. Dyeing reagents are quantitatively loaded in the box body, the inner cavity is sealed through the sealing film, storage and transportation are facilitated, the sealing film is torn off during use, use is convenient, and operation is simplified; the glass slide can enter the slot of the upper cover for dyeing, and the slot is sealed by the sealing plate after the glass slide is taken away, so that a dyeing reagent is favorably stored.

Description

Technical Field

[0001] This application relates to the field of medical devices, and in particular to a staining reagent kit and slide staining apparatus. Background Technology

[0002] HE staining is a commonly used tissue section staining technique in pathology, primarily used to observe and diagnose the morphology, cell morphology, and pathological processes of diseased tissues. This technique can assist doctors in diagnosis, guide treatment, and provide important clues for studying the mechanisms of disease development.

[0003] In related technologies, conventional staining machines have multiple staining tanks placed on the table, each containing various staining reagents. A transfer robotic arm moves a slide holder containing glass slides between the staining tanks to complete the staining process. However, this process is cumbersome, requiring manual addition of staining reagents to each tank. Furthermore, some reagents are volatile and difficult to store and transport, necessitating manual recovery and preservation of the reagents after staining. Summary of the Invention

[0004] This application aims to address at least one of the technical problems existing in the prior art. To this end, this application proposes a staining kit that utilizes the sealing effect of a sealing film for easy storage and transportation, and can be automatically sealed and preserved after use.

[0005] This application also proposes a section staining device for use with the above-mentioned staining kit.

[0006] The staining kit provided in this application includes a box body, a top cover, and a sealing plate. The box body has an inner cavity with an opening at the top for loading staining reagents. The box body is connected to a sealing film that closes the inner cavity. The top cover is installed on the upper end of the box body and covers the opening of the inner cavity. The top cover is provided with a slot communicating with the inner cavity for a glass slide to enter. The sealing plate is connected to the top cover and can switch between a first position and a second position. When the sealing plate is in the first position, the sealing plate closes the slot. When the sealing plate is in the second position, the slot is opened so that the glass slide can be inserted into the slot.

[0007] The staining kit provided in this application has at least the following technical effects:

[0008] The staining reagent is quantitatively loaded into the box, and the inner cavity is sealed with a sealing film to prevent the staining reagent from evaporating and leaking out, which is beneficial for storage and transportation. When using, simply tear off the sealing film, which is convenient and simplifies the operation. The box is connected to a top cover, and the slot on the top cover allows the slide to be inserted for staining. When the slide is inserted, the sealing plate can be pushed open. After the slide is removed, the sealing plate automatically closes the slot under the action of the reset mechanism, which helps to preserve the staining reagent.

[0009] According to some embodiments of the first aspect of this application, the outer wall of the top cover is provided with an insertion port, and the sealing plate can be inserted into the insertion port. The first position is when the sealing plate is inserted into the interior of the top cover, and the second position is when the sealing plate is pulled out to the exterior of the top cover.

[0010] According to some embodiments of the first aspect of this application, the upper cover is provided with a reset mechanism. Under the action of the reset mechanism, the sealing plate is held in the first position, and when the glass slide is inserted into the slot, the sealing plate switches to the second position.

[0011] According to some embodiments of the first aspect of this application, the reset mechanism is a counterweight block connected to the sealing plate, and the counterweight block pushes the sealing plate to keep the slot closed.

[0012] According to some embodiments of the first aspect of this application, the sealing plate is provided with a rotating part, the rotating part is rotatably connected to the upper cover, the counterweight is located on one side of the axis of the rotating part, and the slot is located on the other side of the axis of the rotating part.

[0013] According to some embodiments of the first aspect of this application, the rotating part is a rotating shaft, the inner wall of the upper cover is provided with a shaft hole, and the rotating shaft passes through the shaft hole.

[0014] According to some embodiments of the first aspect of this application, the inner wall of the upper cover is provided with a protruding rotating seat, and the shaft hole is provided in the middle of the rotating seat.

[0015] According to some embodiments of the first aspect of this application, the rotating seat is configured as an annular shape to form the shaft hole, and the outer wall of the rotating seat is provided with a notch communicating with the shaft hole so as to insert the rotating shaft into the shaft hole.

[0016] According to some embodiments of the first aspect of this application, a guide slope is provided on the sidewall of the notch, and the guide slope is located on the side of the notch opposite to the shaft hole.

[0017] According to some embodiments of the first aspect of this application, the rotating part is a bushing, the inner wall of the box is provided with a support shaft, and the bushing is fitted onto the support shaft.

[0018] According to some embodiments of the first aspect of this application, the sealing plate is provided with a rotating part, the rotating part being rotatably connected to the upper cover, and the reset mechanism is a torsion spring, the torsion spring being connected to the sealing plate and pushing the sealing plate to keep the slot closed.

[0019] According to some embodiments of the first aspect of this application, the rotating part is a rotating shaft, the inner wall of the upper cover is provided with a shaft hole, the rotating shaft passes through the shaft hole, the torsion spring is fitted on the rotating shaft, one end of the torsion spring is fixed to the upper cover, and the other end of the torsion spring is fixed to the sealing plate.

[0020] According to some embodiments of the first aspect of this application, the reset mechanism is an elastic sheet, one side of which is fixed to the upper cover and the other side of which is fixed to the sealing plate, thereby driving the sealing plate to remain closed in the slot.

[0021] According to some embodiments of the first aspect of this application, the lower side of the upper cover is provided with a receiving groove, and when the glass slide is inserted into the slot, the sealing plate rotates to allow the counterweight to enter the receiving groove.

[0022] According to some embodiments of the first aspect of this application, the counterweight block has a clearance rounded corner on the side opposite to the sealing plate, and the axis of the clearance rounded corner is consistent with the rotation axis of the sealing plate.

[0023] According to some embodiments of the first aspect of this application, the box or the top cover is provided with an identification area, which is used to affix the identification code of the staining reagent.

[0024] According to some embodiments of the first aspect of this application, the upper surface of the cover is provided with a raised marking portion, and the upper surface of the marking portion forms the marking area.

[0025] According to some embodiments of the first aspect of this application, the upper end surface of the cover is provided with a raised marking portion, and the receiving groove is provided on the lower side of the marking portion.

[0026] According to some embodiments of the first aspect of this application, the counterweight block has a clearance rounded corner on the side opposite to the sealing plate, and the axis of the clearance rounded corner is consistent with the rotation axis of the sealing plate.

[0027] According to some embodiments of the first aspect of this application, the sidewall of the inner cavity is provided with multiple sets of limiting mechanisms, and the edge of the glass slide is connected to the limiting mechanism to keep the glass slide in a vertical state.

[0028] According to some embodiments of the first aspect of this application, the limiting mechanism includes two vertically arranged support plates, with a sliding groove formed between the two support plates, and the edge of the glass slide is inserted into the sliding groove.

[0029] According to some embodiments of the first aspect of this application, the upper opposite surfaces of the two support plates are provided with guide chamfers, and a flared guide channel is formed between the two guide chamfers.

[0030] According to some embodiments of the first aspect of this application, the top cover is provided with a plurality of slots, and the sealing plate corresponds one-to-one with the slots.

[0031] According to some embodiments of the first aspect of this application, the sealing plate is made of an elastic material, and when the glass slide is inserted into the slot, the glass slide pushes open the sealing plate.

[0032] According to some embodiments of the first aspect of this application, the sealing film is an aluminum film, which is adhered to the box body.

[0033] According to some embodiments of the first aspect of this application, the sealing film is a hot melt film, and the hot melt film is hot-melted onto the box body.

[0034] According to some embodiments of the first aspect of this application, the upper surface of the box body forms a sealing surface, and the sealing film is attached to the sealing surface.

[0035] According to some embodiments of the first aspect of this application, a side plate is provided on the outer periphery of the sealing film surface, and a surrounding plate is provided on the outer periphery of the top cover. The surrounding plate surrounds the side plate, and a buckle portion is provided at the lower end of the surrounding plate, which is fastened to the lower end of the side plate.

[0036] According to some embodiments of the first aspect of this application, the box body is made of transparent material or part of the outer wall of the box body is made of transparent material to observe the staining reagent in the inner cavity.

[0037] The slide staining device provided in this application is based on the staining kit provided in this application. Therefore, the slide staining device has all the beneficial effects of the staining kit, which will not be elaborated further. Attached Figure Description

[0038] The above and / or additional aspects and advantages of this application will become apparent and readily understood from the description of the embodiments taken in conjunction with the following drawings, in which:

[0039] Figure 1 This is a schematic diagram of the staining kit according to an embodiment of this application;

[0040] Figure 2 This is an exploded view of the staining kit according to an embodiment of this application. Figure 1 ;

[0041] Figure 3 This is an exploded view of the staining kit according to an embodiment of this application. Figure 2 ;

[0042] Figure 4 This is a cross-sectional view of the staining kit according to an embodiment of this application;

[0043] Figure 5This is a schematic diagram of the structure of the upper cover in an embodiment of this application;

[0044] Figure 6 This is a schematic diagram of the sealing plate structure in an embodiment of this application;

[0045] Figure 7 This is a schematic diagram of the box structure in an embodiment of this application;

[0046] Figure 8 This is a partial top view of the cover and glass slide in an embodiment of this application.

[0047] Figure label:

[0048] Box body 100, inner cavity 101, slide groove 102, sealing film surface 103, support plate 110, guide chamfer 111, side plate 120;

[0049] Top cover 200, slot 201, marking area 202, rotating seat 210, shaft hole 211, notch 212, guide slope 213, marking part 220, receiving groove 221, surrounding plate 230, buckle part 231;

[0050] 300 sealing plate, 310 counterweight, 311 clearance fillet, 320 rotating part;

[0051] 400 glass slides. Detailed Implementation

[0052] The embodiments of this application are described in detail below. Examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain this application, and should not be construed as limiting this application.

[0053] In the description of this application, it should be understood that the orientation descriptions, such as up, down, front, back, left, right, etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this application.

[0054] In the description of this application, "several" means one or more, "more than" means two or more, "greater than," "less than," and "exceeding" are understood to exclude the stated number, while "above," "below," and "within" are understood to include the stated number. The use of "first" and "second" in the description is merely for distinguishing technical features and should not be construed as indicating or implying relative importance, or implicitly indicating the number of indicated technical features, or implicitly indicating the order of the indicated technical features.

[0055] In the description of this application, unless otherwise expressly defined, terms such as "setup," "installation," and "connection" should be interpreted broadly, and those skilled in the art can reasonably determine the specific meaning of the above terms in this application in conjunction with the specific content of the technical solution.

[0056] In related technologies, conventional staining equipment typically uses multiple staining tanks placed on a worktable. These tanks contain various staining reagents, and a robotic arm transfers slide holders containing glass slides between the tanks to complete the staining process. However, this method has the following drawbacks: 1. Multiple staining reagents need to be manually added, making the operation cumbersome; 2. Since some staining reagents are volatile, their purity and stability are affected, reducing their lifespan. Therefore, after staining, they need to be manually collected and stored in specialized containers.

[0057] Therefore, embodiments of the first aspect of this application provide a staining kit that is easy to use by pre-loading a quantitative amount of staining reagent and can be automatically sealed to preserve the staining reagent.

[0058] The staining kit includes a box 100, a top cover 200, and a sealing plate 300, and is designed to provide an easy-to-use staining kit that can effectively preserve staining reagents and precisely control the amount of staining reagents used.

[0059] The box 100, as the main body of the staining kit, is designed with an inner cavity 101 with an opening at the top for holding the staining reagents. Considering the possibility of staining reagent leakage during transportation and storage after pre-loading, the box 100 is connected to a sealing film. The sealing film seals the inner cavity 101 of the kit, ensuring that the staining reagents in the kit will not leak or become contaminated during storage and transportation. The sealing film achieves a secure seal for the staining kit and is easy to use; simply tear off the sealing film.

[0060] The sealing film can be made of aluminum film, which has strong corrosion resistance, will not be damaged by the dyeing reagent, and will not affect the cleanliness of the dyeing reagent. Furthermore, aluminum film is easy to tear and convenient to use. Alternatively, hot melt film can be used. Hot melt film is a thin film material with a specific melting point; after reaching its melting point, it softens rapidly and adheres to the contact surface. In the dyeing kit of this application, the box body 100 is designed with a sealing surface 103. The hot melt film is bonded to the sealing surface 103 of the box body 100 by heat fusion, thereby sealing the inner cavity 101 of the kit.

[0061] The top cover 200 is installed on the upper end of the box body 100 to cover the opening of the inner cavity 101, thereby reducing the evaporation and contamination of the staining reagent. Furthermore, the top cover 200 is provided with a slot 201 communicating with the inner cavity 101. The width and length of the slot 201 match the size of the slide 400, allowing the slide 400 to be inserted into the inner cavity 101 of the box body 100 through the slot 201, where it contacts the staining reagent for staining. A sealing plate 300 is connected to the top cover 200 and can switch between a first position and a second position. When the sealing plate 300 is in the first position, it facilitates the insertion of the slot 201. When the slide 400 is inserted into the slot 201, the sealing plate 300 can switch to the second position, thereby opening the slot 201 to allow the slide 400 to smoothly enter the inner cavity 101. In addition, the reagent kit has the advantages of small size, light weight and easy portability, and can be widely used in laboratories, hospitals, research institutions and other places.

[0062] The volume of the inner cavity 101 of the container 100 is precisely calculated to hold a sufficient amount of staining reagent to meet the needs of multiple staining operations or the staining requirements of multiple slides 400. A fixed amount of staining reagent can be pre-loaded into the container 100 according to the number of slides 400 to be stained or the production process of the staining equipment. Volume markings can be provided on the outer wall of the container 100 or the side wall of the inner cavity 101 to facilitate the injection of a fixed amount of staining reagent. The container 100 can also be made of transparent material, or part of its outer wall can be made of transparent material, allowing direct observation of the staining reagent level. With a pre-loaded fixed amount of staining reagent in the container 100, users can perform staining operations without manually adding staining reagent, simplifying the staining process and eliminating potential errors and contamination problems that may occur when manually adding staining reagent. Furthermore, because the amount of staining reagent used is precisely controlled, the accuracy and consistency of the staining results are also improved.

[0063] The width and length of the slot 201 need to be rationally designed according to the dimensions of the slide 400 to ensure that the slide 400 can be smoothly inserted into the slot 201 and reach the inner cavity 101. At the same time, a guide structure, such as a chamfer or bevel, can be provided at the opening of the slot 201 to facilitate easier insertion of the slide 400 into the slot 201. Understandably, since the tissue section is located on one side of the slide 400, to prevent the cover 200 from colliding with the tissue section, such as... Figure 8 As shown, the side wall of the slot 201 is provided with a groove. When the slide 400 is inserted into the slot 201, the position of the tissue slice corresponds to the groove, thereby avoiding the tissue slice and preventing collision and damage to the tissue slice.

[0064] The staining kit provided in this application has the following beneficial effects:

[0065] 1. Leakage prevention during transportation and storage: The inner cavity 101 is sealed with a sealing film to prevent the dyeing reagent from evaporating and leaking out, which is beneficial for storage and transportation.

[0066] 2. Facilitates the preservation of staining reagents: The box body 100 is connected to a top cover 200, and the slot 201 of the top cover 200 allows the slide 400 to enter for staining. After the slide 400 is removed, the sealing plate 300 can seal the slot 201, thereby effectively preventing the staining reagent from evaporating and leaking out. This not only helps to preserve the purity and stability of the staining reagent, but also extends the service life of the staining reagent.

[0067] 3. Convenient to use: A fixed amount of dyeing reagent is loaded into the inner cavity 101 of the box 100. The inner cavity 101 is sealed with a sealing film to prevent the dyeing reagent from evaporating and leaking. When using, simply tear open the sealing film to use it, eliminating the tedious operation of manually adding dyeing reagent and simplifying the usage process.

[0068] Understandably, the box 100 can be made of a transparent material so that the user can clearly observe the state and volume of the staining reagent in the inner cavity 101. The top cover 200 can also be made of a transparent material so that the user can clearly observe the state and volume of the staining reagent in the inner cavity 101.

[0069] It is understood that in some embodiments of this application, the outer wall of the top cover 200 is provided with an insertion port, through which the sealing plate 300 can be inserted into the interior of the top cover 200 (the first position). Pulling the sealing plate 300 out of the insertion port to the outside of the top cover 200 constitutes the second position. Under normal conditions, the sealing plate 300 is in the first position, fulfilling the requirement of sealing the slot 201 and preventing the staining reagent from evaporating. During staining, pulling the sealing plate 300 out to the second position allows the slide 400 to be inserted into the slot 210. After staining, the slide 400 is removed, and then the sealing plate 300 is inserted back into the top cover 200 to reseal the slot 201.

[0070] In some other embodiments of this application, the top cover 200 is provided with a reset mechanism. Under the action of the reset mechanism, the sealing plate 300 is held in the first position. When the slide 400 is inserted into the slot 201, the sealing plate 300 switches to the second position, opening the slot 201 to allow the slide 400 to enter.

[0071] Reference Figures 2 to 6The reset mechanism is a counterweight 310, which is integrally formed or connected to the sealing plate 300 by some means of connection (such as bolts, rivets, or adhesives). The weight of the counterweight 310 is precisely calculated to ensure that, in the absence of external force, the weight of the counterweight 310 keeps the sealing plate 300 in the first position of closing the slot 201. When it is necessary to open the sealing plate 300, simply insert the glass slide 400 into the slot 201. The glass slide 400 applies a pushing force to the sealing plate 300, overcoming the weight of the counterweight 310, allowing the sealing plate 300 to easily leave the slot 201 and switch to the second position. When the external force disappears, the weight of the counterweight 310 will automatically cause the sealing plate 300 to return and close the slot 201, thus ensuring that the reagent kit remains closed when not in use, preventing reagent evaporation and contamination. Under the action of the counterweight 310, the sealing plate 300 has an upward rotation tendency, which is blocked by the top cover 200. Therefore, the sealing plate 300 remains in contact with the top cover 200 and the closed slot 201.

[0072] Furthermore, to further improve the reliability and durability of the sealing plate 300, some cushioning or vibration damping material can be added at the contact point between the upper cover 200 and the sealing plate 300 to reduce friction and wear during collisions. Simultaneously, the shape and size of the counterweight 310 can be optimized to ensure it can more effectively drive the movement of the sealing plate 300 and reduce unnecessary space occupation.

[0073] Reference Figure 6 In some embodiments of this application, the sealing plate 300 of the staining kit is designed to have a rotating part 320, which is rotatably connected to the top cover 200, allowing the sealing plate 300 to rotate around a fixed axis to open or close the slot 201. A counterweight 310 is disposed on one side of the axis of the rotating part 320, and the slot 201 is located on the other side of the axis of the rotating part 320. When no external force is applied, the counterweight 310 drives the sealing plate 300 to rotate under the action of gravity, so that the sealing plate 300 is held in a first position.

[0074] In practical applications, when the user needs to open the sealing plate 300, a force is applied to overcome the gravity of the counterweight 310, causing the sealing plate 300 to rotate around the rotating part 320. The sealing plate 300 is opened to a sufficient angle, allowing the slide 400 to easily pass through the slot 201. After the slide 400 leaves, the gravity of the counterweight 310 will automatically cause the sealing plate 300 to rotate and return to the first position, thus ensuring the closure of the slot 201.

[0075] Reference Figure 6The rotating part 320 is designed as a pivot, and the inner wall of the upper cover 200 is designed with a pivot hole 211 to accommodate the pivot. The pivot passes through the pivot hole 211, realizing the hinge between the sealing plate 300 and the upper cover 200. The sealing plate 300 rotates based on the pivot. Pivots are provided at both ends of the sealing plate 300 to provide rotational support for both ends of the sealing plate 300, ensuring stability during rotation. The counterweight 310 is located on the bottom surface of the sealing plate 300 and is offset on the side of the pivot away from the slot 201. Figure 4 As shown, when the slide 400 is inserted into the slot 201, the sealing plate 300 rotates, and the counterweight 310 is lifted. When the slide 400 is removed, under the action of gravity, the counterweight 310 drives the sealing plate 300 to rotate, returning to the first position to close the slot 201.

[0076] It is understandable that the shaft hole 211 can be a countersunk hole on the inner wall of the top cover 200, or it can be a protrusion on the inner wall of the top cover 200. The shaft hole 211 is set on the protrusion. It can be selected and designed according to the material, wall thickness and other conditions of the top cover 200, and both can meet the usage requirements.

[0077] Reference Figure 5 and Figure 6 A raised rotating seat 210 is designed on the inner wall of the upper cover 200. A shaft hole 211 is provided in the middle of the rotating seat 210 for mounting the rotating shaft. The size and shape of the shaft hole 211 are matched with the rotating shaft to ensure that the rotating shaft can be smoothly inserted and rotated freely in the shaft hole 211.

[0078] Considering the cylindrical shape of the shaft, the rotating seat 210 is designed as an annular shape. This not only conforms to the cylindrical characteristics of the shaft but also makes the drilling of the shaft hole 211 easier and more precise. Simultaneously, the annular design reduces the space occupied by the rotating seat 210. A notch 212 communicating with the shaft hole 211 is provided on the outer wall of the rotating seat 210. The function of the notch 212 is to facilitate the installation and removal of the shaft. When it is necessary to insert the shaft into the shaft hole 211, one end of the shaft is simply inserted into the shaft hole 211 through the notch 212, completing the installation easily. Similarly, when it is necessary to remove the shaft, it can also be removed from the shaft hole 211 through the notch 212.

[0079] On the side of the notch 212 opposite to the shaft hole 211, a guide slope 213 is provided. The function of the guide slope 213 is to further simplify the installation process of the shaft and improve the ease of operation. The guide slope 213 has two main functions. First, it guides the shaft into the shaft hole 211. When the user brings one end of the shaft close to the notch 212, the guide slope 213 will naturally guide the shaft into the shaft hole 211 in the correct direction, which helps to improve installation efficiency. Second, the guide slope 213 also reduces friction and wear. During the process of the shaft entering the shaft hole 211, the guide slope 213 can gradually guide the shaft to contact the inner wall of the shaft hole 211, thereby avoiding collisions and wear caused by sudden impacts, extending the service life of the shaft and the shaft hole 211, and improving the overall durability of the staining kit.

[0080] It is understood that in some other embodiments of this application, the rotating part 320 is designed as a bushing, and a support shaft is correspondingly provided on the inner wall of the upper cover 200. The bushing is fitted onto the support shaft to realize the rotation of the sealing plate 300. Through the rotational connection between the bushing and the support shaft, the sealing plate 300 can rotate smoothly around the support shaft, thereby facilitating the opening or closing of the slot 201. In addition, the surface of the support shaft is set as a smooth cylindrical surface to reduce friction during rotation. For example, the support shaft can be made of metal, which has high strength and wear resistance, is easy to process into a smooth surface, reduces wear during use, and improves service life.

[0081] Understandably, the sealing plate 300 is provided with a rotating part 320, which is rotatably connected to the upper cover 200, allowing the sealing plate 300 to rotate relative to the upper cover 200, thereby facilitating the opening or closing of the slot 201. The reset mechanism is a key component of the staining kit, capable of automatically pushing the sealing plate 300 back to its closed position. In some embodiments, the reset mechanism employs a torsion spring, a flexible metal element similar in shape to a helical spring. A fixing point is provided at one end of the torsion spring for fixing it to the box body 100; a connection point is provided at the other end for connecting to the sealing plate 300. When the sealing plate 300 is opened, the torsion spring is stretched or twisted, generating a certain rebound force and storing energy. When the external force disappears, the rebound force of the torsion spring pushes the sealing plate 300 back to the first position, closing the slot 201 to reduce the evaporation of the staining reagent.

[0082] The rotating part 320 is configured as a rotating shaft, which passes through a pre-set shaft hole 211 on the inner wall of the upper cover 200. A torsion spring is fitted onto the rotating shaft, with one end of the torsion spring firmly fixed to the upper cover 200 and the other end connected to the sealing plate 300. During assembly, a preload is applied to the torsion spring, the magnitude of which directly affects the stability and reliability of the sealing plate 300's automatic reset. Multiple tests and experiments are conducted to determine a suitable preload range, ensuring that the sealing plate 300 can smoothly and quickly return to the closed position after opening, while avoiding excessive impact that could damage the upper cover 200.

[0083] It is understood that in some other embodiments of this application, the reset mechanism adopts an elastic sheet structure, and the sealing plate 300 is responsible for sealing the slot 201 to prevent reagent evaporation, leakage, or contamination. The elastic sheet is a thin sheet part with elastic deformation capability. One side of the elastic sheet is fixed to the upper cover 200, which can be done by adhesive bonding, screw fixing, or other mechanical connection methods. The other side of the elastic sheet is fixedly connected to the sealing plate 300.

[0084] When the sealing plate 300 is opened, the elastic sheet undergoes elastic deformation, storing a certain amount of elastic potential energy. The deformation can be bending, twisting, or stretching, depending on the shape and fixing method of the elastic sheet. When the external force disappears, the elastic sheet uses its stored elastic potential energy to push the sealing plate 300 back to the closed slot 201.

[0085] In addition, a limiting structure can be provided on the elastic sheet or the top cover 200 to prevent the elastic sheet from being excessively stretched or bent during deformation, thereby extending the service life of the elastic sheet. The limiting structure can be a protrusion, a groove, or other shape, which can provide additional support and restraint when the elastic sheet deforms.

[0086] It is understood that in some other embodiments of this application, the sealing plate 300 is made entirely of an elastic material and has the ability to deform elastically. In the first position, the sealing plate 300 keeps the slot 201 closed. When the slide 400 is inserted into the slot 201, the slide 400 can push the sealing plate 300 to deform, thereby entering the inner cavity 101. After staining is completed, the slide 400 is removed, and the sealing plate 300 automatically returns to the first position, resealing the slot 201.

[0087] Reference Figure 1In some embodiments of this application, the top cover 200 is provided with an identification area 202, which is used to affix the identification code (such as a barcode, QR code, etc.) of the staining reagent. This aims to improve the automated identification and ease of use of the staining kit. The slide staining device can be equipped with a camera to automatically capture and identify the identification code of the staining reagent, enabling automatic tracking and use. It can also record the number of uses and accurately control the amount of staining reagent used. Placing the identification area 202 on the top cover 200 facilitates user observation and barcode scanning. The top cover 200 is located at the top of the staining kit, making the identification code easier to find and recognize.

[0088] Of course, the labeling area 202 can also be set in other positions on the top cover 200 or the box body 100, such as setting a special groove to stick the identification code of the dyeing reagent. The groove helps to protect the identification code and prevent scratches from causing the identification code to fall off.

[0089] In other embodiments, a raised marking portion 220 is provided on the upper surface of the cover 200. Preferably, the marking portion 220 is designed as an elongated strip, and the upper surface of the marking portion 220 is used as the marking area 202, which not only conforms to the common shape of reagent kit labels in most laboratories, but also facilitates quick identification and retrieval.

[0090] Reference Figure 4 A receiving groove 221 can be provided on the lower side of the marking part 220. When the staining operation is performed, the slide 400 is inserted into the slot 201 of the cover 200. The sealing plate 300 will rotate under the push of the slide 400, and at the same time drive the counterweight 310 to rotate. The counterweight 310 then enters the receiving groove 221 on the lower side of the marking part 220, making full use of the space. The receiving groove 221 is set by the protruding marking part 220 to provide movement space for the counterweight 310, which is conducive to improving the space utilization rate of the inner cavity 101 of the box body 100.

[0091] It is understood that in some other embodiments, the receiving groove 221 is disposed on the lower end face of the upper cover 200, but not on the lower side of the marking area 202. For example, the marking area 202 can be disposed on the box body, or the marking area 202 can be disposed on the upper cover 200, but offset from the position of the receiving groove 221. For example, the upper end face of the upper cover 200 can be flat or other shapes. When performing staining operations, the slide 400 is inserted into the slot 201 of the upper cover 200, and the sealing plate 300 will rotate under the push of the slide 400, while driving the counterweight 310 to rotate and rise, and the counterweight 310 enters the receiving groove 221.

[0092] Furthermore, to prevent the counterweight 310 from colliding with the cover 200 during rotation, a clearance rounded corner 311 is provided on the side of the counterweight 310 away from the sealing plate 300. The axis of the clearance rounded corner 311 is consistent with the axis of rotation of the sealing plate 300 (the axis of the rotating part 320). During the rotation of the sealing plate 300, the distance between the surface of the counterweight 310 and the axis of the rotating part 320 remains unchanged. Due to the presence of the clearance rounded corner 311, the counterweight 310 can easily enter the receiving groove 221 during movement, preventing damage from collisions.

[0093] It is understood that in some embodiments of this application, the box 100 is designed with one or more cavities 101 for accommodating the slide 400 and the staining agent. Multiple sets of limiting mechanisms are provided on the side wall of the cavity 101. The limiting mechanisms are used to keep the slide 400 in a vertical state. The slide 400 reacts under the immersion of the staining agent, which is conducive to the full contact of the slices on the slide 400 with the staining agent and helps to obtain accurate staining results.

[0094] Reference Figure 4 and Figure 7 Each limiting mechanism consists of two vertically arranged support plates 110, which are arranged in parallel. The space between the two support plates 110 forms a groove 102, which extends vertically along the side wall of the inner cavity 101. The groove 102 is used to accommodate the edge of the slide 400. During the staining process, the edge of the slide 400 is inserted into the groove 102, and the two support plates 110 clamp the slide 400, keeping it vertical. The slide 400 reacts under the immersion of the staining reagent, which helps the sections on the slide 400 to fully contact the staining reagent and contributes to accurate staining results.

[0095] In addition, multiple grooves 102 can be formed on the sidewall of the inner cavity 101 to accommodate multiple slides 400 for staining operations. The widths of the multiple grooves 102 can be the same or different to accommodate slides 400 of different sizes. By selecting different grooves 102, the distance between two slides 400 can be adjusted to meet diverse staining needs.

[0096] Furthermore, to facilitate the insertion of the slide 400 into the slide groove 102, guide chamfers 111 are provided on the upper opposite surfaces of the two support plates 110. The two guide chamfers 111 are inclined inward into the slide groove 102 at a certain angle, thereby forming a funnel-shaped guide channel between the two guide chamfers 111. This helps to improve the convenience of operation for the user, especially in the operation of inserting the slide 400 into the slide groove 102, which basically eliminates the problem of the slide 400 being stuck by the top of the support plate 110.

[0097] Understandably, each staining kit can contain one or more staining reagents. Several partitions can be installed within the inner cavity 101, acting as space dividers to form multiple cavities, allowing the staining kit to hold various staining reagents. The size and shape of each cavity can be designed according to the usage amount of the corresponding staining reagent to ensure optimal compatibility and space utilization.

[0098] In practical use, different types of staining reagents can be separately loaded into these separated compartments according to experimental needs. This design can speed up the staining process; for example, three staining reagents can be used consecutively in one staining kit, saving time. Correspondingly, multiple identification areas 202 can be set on the top cover 200, with each identification area 202 having an identification code corresponding to a different staining reagent, facilitating accurate tracking and recording of the usage of various staining reagents.

[0099] It is understandable that the partition can also serve as a structure to form the slide 102. For example, a partition combined with a support plate 110 can form the slide 102, which can both maintain the vertical state of the slide 400 and serve as a divider, simplifying the structure of the box 100.

[0100] Furthermore, to simplify the structure of the box 100, the upper end face of the box 100 is set as the sealing film surface 103. After the staining reagent is loaded, the sealing film is attached to the upper end face of the box 100 to seal the inner cavity 101 and prevent the staining reagent from leaking out. Even if the staining kit is tilted during transportation and storage, the staining reagent will not leak out, ensuring the reliability of use. It also prevents the staining reagent from evaporating and ensures the stability of the liquid volume of the staining reagent.

[0101] Reference Figure 4 and Figure 5 In some embodiments of this application, the box body 100 has a side plate 120 around the outer periphery of the sealing film surface 103, and the upper cover 200 has a surrounding plate 230 around the outer periphery. After the upper cover 200 is assembled with the box body 100, the surrounding plate 230 surrounds the side plate 120, and the upper end of the side plate 120 abuts against the upper cover 200 to support the upper cover 200. A snap-fit ​​part 231 is provided at the lower end of the surrounding plate 230. Using the principle of snap-fit ​​connection, the surrounding plate 230 can be firmly fastened to the lower end of the side plate 120 through the snap-fit ​​part 231, so that the upper cover 200 is fixed to the box body 100.

[0102] In practical applications, simply place the top cover 200 on the box body 100 and press down slightly to ensure that the latching part 231 of the side panel 230 and the lower end of the side panel 120 are tightly engaged. This assembly is not only simple to operate but also highly reliable and stable. Even if the top cover 200 is shaken or bumped during transportation or storage, it will remain firmly fixed to the box body 100 and will not come off.

[0103] Furthermore, some dyeing reagents require heating during the dyeing process, which increases the air pressure in the inner cavity 101. This pressure needs to be released through the gap between the side plate 120 and the surrounding plate 230. The side plate 120 and the surrounding plate 230 form a labyrinthine channel, which allows the inner cavity 101 to connect to the outside for pressure release while reducing the entry of external dust into the inner cavity 101, thus avoiding contamination of the dyeing reagents.

[0104] Reference Figure 1 In some embodiments of this application, the upper cover 200 is provided with multiple slots 201, allowing multiple slides 400 to enter the inner cavity 101 for staining, thereby improving the speed of large-scale detection and saving time. It can work in conjunction with the partitions inside the housing 100 to sequentially use various staining reagents. Identification parts 220 correspond one-to-one with slots 201. An identification code can be affixed to each identification part 220, and scanning the code records the number of times a slide 400 enters and exits each slot 201, thus accurately counting the number of times staining reagents are used, preventing waste and overuse of staining reagents, and avoiding staining failures. Furthermore, the multiple slots 201 of the upper cover 200 can be of the same or different specifications to meet the staining needs of slides 400 of various sizes.

[0105] The second aspect of this application provides a slide staining device, which includes the staining kit of the first aspect embodiment, encompasses all the technical solutions of the staining kit, and has all the technical effects of the staining kit, which will not be repeated here.

[0106] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "illustrative embodiment," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of this application. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0107] Although embodiments of this application have been shown and described, those skilled in the art will understand that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of this application, the scope of which is defined by the claims and their equivalents.

Claims

1. A staining kit, characterized in that, include: The box (100) has an inner cavity (101) with an opening at the top for holding staining reagents, and the box (100) is connected to a sealing film that closes the inner cavity (101). A top cover (200) is installed on the upper end of the box body (100) and covers the opening of the inner cavity (101). The top cover (200) is provided with a slot (201) communicating with the inner cavity (101) for the glass slide (400) to enter. A sealing plate (300) is connected to the upper cover (200). The sealing plate (300) can switch between a first position and a second position. When the sealing plate (300) is in the first position, the sealing plate (300) closes the slot (201). When the sealing plate (300) is in the second position, the slot (201) is opened so that the slide (400) can be inserted into the slot (201).

2. The staining kit according to claim 1, characterized in that, The outer wall of the top cover (200) is provided with an insertion port, and the sealing plate (300) can be inserted into the insertion port. The sealing plate (300) is inserted into the inside of the top cover as the first position, and the sealing plate (300) is pulled out to the outside of the top cover as the second position.

3. The staining kit according to claim 1, characterized in that, The upper cover (200) is provided with a reset mechanism. Under the action of the reset mechanism, the sealing plate (300) is held in the first position. When the slide (400) is inserted into the slot (201), the sealing plate (300) switches to the second position.

4. The staining kit according to claim 3, characterized in that, The reset mechanism is a counterweight (310), which is connected to the sealing plate (300). The counterweight (310) drives the sealing plate (300) to keep the slot (201) closed.

5. The staining kit according to claim 4, characterized in that, The sealing plate (300) is provided with a rotating part (320), which is rotatably connected to the upper cover (200). The counterweight (310) is located on one side of the axis of the rotating part (320), and the slot (201) is located on the other side of the axis of the rotating part (320).

6. The staining kit according to claim 5, characterized in that, The rotating part (320) is a rotating shaft, and the inner wall of the upper cover (200) is provided with a shaft hole (211), through which the rotating shaft passes.

7. The staining kit according to claim 6, characterized in that, The inner wall of the upper cover (200) is provided with a raised rotating seat (210), and the shaft hole (211) is located in the middle of the rotating seat (210).

8. The staining kit according to claim 7, characterized in that, The rotating seat (210) is configured as an annular shape to form the shaft hole (211), and the outer wall of the rotating seat (210) is provided with a notch (212) communicating with the shaft hole (211) so that the rotating shaft can be inserted into the shaft hole (211).

9. The staining kit according to claim 8, characterized in that, The sidewall of the notch (212) is provided with a guide slope (213), which is located on the side of the notch (212) away from the shaft hole (211).

10. The staining kit according to claim 5, characterized in that, The rotating part (320) is a bushing, and the inner wall of the upper cover (200) is provided with a support shaft, and the bushing is fitted onto the support shaft.

11. The staining kit according to claim 3, characterized in that, The sealing plate (300) is provided with a rotating part (320), which is rotatably connected to the upper cover (200). The reset mechanism is a torsion spring, which is connected to the sealing plate (300) and pushes the sealing plate (300) to keep the slot (201) closed.

12. The staining kit according to claim 11, characterized in that, The rotating part (320) is a rotating shaft. The inner wall of the upper cover (200) is provided with a shaft hole (211). The rotating shaft passes through the shaft hole (211). The torsion spring is fitted onto the rotating shaft. One end of the torsion spring is fixed to the upper cover (200), and the other end of the torsion spring is fixed to the sealing plate (300).

13. The staining kit according to claim 3, characterized in that, The reset mechanism is an elastic sheet, one side of which is fixed to the upper cover (200) and the other side of which is fixed to the sealing plate (300), thereby driving the sealing plate (300) to remain closed in the slot (201).

14. The staining kit according to claim 4, characterized in that, The lower side of the upper cover (200) is provided with a receiving groove (221). When the glass slide (400) is inserted into the slot (201), the sealing plate (300) rotates to allow the counterweight (310) to enter the receiving groove (221).

15. The staining kit according to claim 14, characterized in that, The counterweight (310) has a relief fillet (311) on the side away from the sealing plate (300), and the axis of the relief fillet (311) is consistent with the rotation axis of the sealing plate (300).

16. The staining kit according to any one of claims 2 to 15, characterized in that, The box body (100) or the top cover (200) is provided with an identification area (202), which is used to affix the identification code of the staining reagent.

17. The staining kit according to claim 16, characterized in that, The upper surface of the cover (200) is provided with a raised marking part (220), and the upper surface of the marking part (220) forms the marking area (202).

18. The staining kit according to claim 15, characterized in that, The upper end face of the cover (200) is provided with a raised marking part (220), and the receiving groove (221) is provided on the lower side of the marking part (220).

19. The staining kit according to any one of claims 1 to 15, characterized in that, The inner cavity (101) is provided with multiple sets of limiting mechanisms on its sidewalls. The edge of the slide (400) is connected to the limiting mechanism so that the slide (400) remains vertical.

20. The staining kit according to claim 19, characterized in that, The limiting mechanism includes two vertically arranged support plates (110), and a groove (102) is formed between the two support plates (110). The edge of the glass slide (400) is inserted into the groove (102).

21. The staining kit according to claim 20, characterized in that, The upper opposite surfaces of the two support plates (110) are provided with guide chamfers (111), and a trumpet-shaped guide channel is formed between the two guide chamfers (111).

22. The staining kit according to any one of claims 1 to 15, characterized in that, The top cover (200) is provided with a plurality of slots (201), and the sealing plate (300) corresponds one to one of the slots (201).

23. The staining kit according to claim 1, characterized in that, The sealing plate (300) is made of elastic material. When the slide (400) is inserted into the slot (201), the slide (400) pushes open the sealing plate (300).

24. The staining kit according to claim 1, characterized in that, The sealing film is an aluminum film, which is adhered to the box body (100).

25. The staining kit according to claim 1, characterized in that, The sealing film is a hot melt film, which is hot-melted onto the box body (100).

26. The staining kit according to any one of claims 1 to 15, characterized in that, The upper surface of the box (100) forms a sealing surface (103), and the sealing film is attached to the sealing surface (103).

27. The staining kit according to claim 26, characterized in that, The outer periphery of the sealing film surface (103) is provided with a side plate (120), and the outer periphery of the top cover (200) is provided with a surrounding plate (230). The surrounding plate (230) surrounds the side plate (120), and the lower end of the surrounding plate (230) is provided with a buckle part (231). The buckle part (231) is fastened to the lower end of the side plate (120).

28. The staining kit according to any one of claims 1 to 15, characterized in that, The box (100) is made of transparent material or part of the outer wall of the box (100) is made of transparent material so as to observe the staining reagent in the inner cavity (101).

29. A section staining apparatus, characterized in that, Includes the staining kit as described in any one of claims 1 to 22.

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