Detection device and sequencer

Abstract

The utility model provides a detection device which comprises a frame body and a mounting plate which are fixedly connected, and the frame body and the mounting plate define a containing space; a carrying platform module is accommodated in the accommodating space, the mounting plate and the carrying platform module are oppositely arranged at an interval, and an imaging assembly is supported on one side, deviating from the carrying platform module, of the mounting plate; the frame body comprises a bottom plate which is opposite to the mounting plate and is arranged at an interval and supporting plates which extend towards the mounting plate from two opposite sides of the bottom plate, and the carrying platform module is supported by the bottom plate; the imaging assembly comprises an objective lens module which penetrates through the mounting plate and extends into the accommodating space, and a sensor module which is optically connected with the objective lens module; orthographic projections of the sensor module and the objective lens module on the mounting plate are not overlapped; the detection device further comprises a shock absorber which is connected with the supporting plate and supports the frame body, and the orthographic projection of the shock absorber on the supporting plate in the direction parallel to the bottom plate at least covers part of the supporting plate. The detection device is beneficial for reducing the overall size of the device. The utility model further provides a sequencer.

Description

Technical Field

[0001] This application relates to the field of optical detection technology, and in particular to a detection device and a sequencer. Background Technology

[0002] Gene sequencers are highly complex technological integrations involving multiple disciplines and fields, including optics, mechanics, electronics, fluid dynamics, software, and algorithms. Mechanically, gene sequencers primarily involve multiple hardware modules such as fluid dynamics, biochemistry, temperature control, electronics, motion control platforms, fluorescence detection systems, and computers.

[0003] Gene sequencers are complex devices with numerous components that are scattered and independent, resulting in low integration and space utilization. This also makes gene sequencers particularly large, causing many inconveniences in transportation, installation, and operation. Utility Model Content

[0004] This application provides a detection device, including a frame and a mounting plate fixedly connected together, the frame and mounting plate enclosing a receiving space; a stage module is housed within the receiving space, the mounting plate is opposite to and spaced apart from the stage module, and an imaging component is supported on the side of the mounting plate away from the stage module; the frame includes a base plate opposite to and spaced apart from the mounting plate and support plates extending from opposite sides of the base plate toward the mounting plate, the stage module being supported by the base plate; the imaging component includes an objective lens module penetrating the mounting plate and extending into the receiving space, and a sensor module optically connected to the objective lens module; the orthographic projections of the sensor module and the objective lens module on the mounting plate do not overlap; the detection device further includes a vibration damper connected to the support plate and supporting the frame, the vibration damper's orthographic projection along a direction parallel to the base plate on the support plate at least partially covering the support plate.

[0005] In at least one embodiment of this application, the vibration damper includes a support rod corresponding to the support plate and a vibration damping component connected between the support rod and the support plate; the frame, the stage module, and the imaging component together form a block to be damped, a plurality of vibration dampers are arranged around the outer periphery of the block to be damped, and the vibration damping components of the plurality of vibration dampers form a damping surface, the center of the damping surface coincides with the center of gravity of the block to be damped.

[0006] In at least one embodiment of this application, the vibration damper further includes a support foot that bends and extends from one end of the support rod and is disposed opposite to the base plate. The vibration damping assembly includes an upper base, a lower base, and a vibration damping pad sandwiched between the upper base and the lower base. The upper base is fixed to the support plate, and the lower base is fixed to the support rod.

[0007] In at least one embodiment of this application, the vibration damping pad includes at least one of a vibration isolator and a damper.

[0008] In at least one embodiment of this application, the support plate has a mounting portion protruding from the side opposite to the receiving space, which is fixed to the upper base, and the mounting portion covers the end of the upper base away from the vibration damping pad.

[0009] In at least one embodiment of this application, the detection device further includes a base that is opposite to and spaced apart from the base plate, and the support foot is located between the base plate and the base and fixed to the base.

[0010] In at least one embodiment of this application, the imaging component includes a light guiding device located between the objective lens module and the sensor module. The light guiding device is located at one end of the objective lens module away from the stage module and is optically connected to both the objective lens module and the imaging component.

[0011] In at least one embodiment of this application, the sensor module includes a first imaging channel and a second imaging channel, each of which includes an image sensor that acquires light signals of different wavelengths; the first imaging channel and the second imaging channel are respectively connected to different sides of the light guiding device parallel to the mounting plate and their orthogonal projections on the mounting plate do not overlap.

[0012] In at least one embodiment of this application, the sensor module further includes a focusing module optically connected to the light guiding device, wherein the orthographic projection of the focusing module on the mounting plate is at least partially located between the first imaging channel and the second imaging channel.

[0013] In at least one embodiment of this application, the focusing module is optically connected to the side of the light guiding device away from the mounting plate, including: a support frame fixed on the mounting plate and a focuser supported by the support frame, wherein the height of the focuser relative to the mounting plate is greater than that of the first imaging channel and the second imaging channel.

[0014] In at least one embodiment of this application, the imaging component further includes a driver connected to the objective lens module and mounted on the mounting plate. The driver includes a stator fixed to the mounting plate and a mover passing through the mounting plate and connected to the objective lens module. The mover drives the objective lens module to be movably disposed relative to the mounting plate. The projection of the driver on the mounting plate does not overlap with the sensor module.

[0015] A second aspect of this application provides a sequencer including the detection device described in any of the preceding claims.

[0016] The aforementioned detection device and sequencer include a fixedly connected frame and mounting plate, which form a receiving space. The stage module is housed within this space, and the imaging components are mounted on the mounting plate. This design results in a compact overall structure for the detection device, improving its overall integration and miniaturization. Vibration dampers supporting the frame further reduce overall vibration. Attached Figure Description

[0017] Figure 1 This is a three-dimensional structural diagram of the detection device according to an embodiment of this application.

[0018] Figure 2 for Figure 1 A three-dimensional structural diagram of the main support module and vibration damper.

[0019] Figure 3 for Figure 2 Exploded view of the main support module and vibration damper.

[0020] Figure 4 for Figure 3 A three-dimensional structural diagram of the mounting plate.

[0021] Figure 5 This is another three-dimensional structural diagram of the detection device according to an embodiment of this application.

[0022] Figure 6 for Figure 1 A three-dimensional structural diagram of the imaging component.

[0023] Explanation of main component symbols

[0024] Detection device: 100;

[0025] Main support modules: 10;

[0026] Detection space: 11;

[0027] Frame size: 12;

[0028] First support plate: 121;

[0029] Mounting holes: 1211, 1231;

[0030] Installation Department: 1212, 1232;

[0031] Base plate: 122;

[0032] Moving plane: 1221;

[0033] Second support plate: 123;

[0034] Mounting plate: 13;

[0035] Mounting plane: 131;

[0036] Reference mounting surface: 132;

[0037] Mounting positioning hole: 133;

[0038] Gap in the gap: 134;

[0039] Reinforcing rib: 135;

[0040] concavity: 136;

[0041] Platform modules: 20;

[0042] Mobile platform: 21;

[0043] Load-bearing surface: 211;

[0044] Installation position: 212;

[0045] Opening: 2121;

[0046] Slide handling device: 22;

[0047] Shock absorber: 30;

[0048] Support rod: 31;

[0049] Support legs: 32;

[0050] Vibration damping components: 33;

[0051] Upper base: 331;

[0052] Lower base: 332;

[0053] Vibration damping pad: 333;

[0054] Imaging components: 40;

[0055] Light source: 41;

[0056] Objective lens module: 42;

[0057] Sensor module: 43;

[0058] First imaging channel: 431;

[0059] First tube scope: 4311;

[0060] First image sensor: 4312;

[0061] Second imaging channel: 432;

[0062] Second tube scope: 4321;

[0063] Second image sensor: 4322;

[0064] Focusing module: 433;

[0065] Support frame: 4331;

[0066] Focusing module: 4332;

[0067] Light guiding device: 44;

[0068] Drive: 45;

[0069] Stator: 451;

[0070] Motion: 452;

[0071] Base: 50.

[0072] The following detailed description, in conjunction with the accompanying drawings, will further illustrate this application. Detailed Implementation

[0073] This application provides a detection device, including a fixedly connected frame and mounting plate. The frame and mounting plate house a stage module and mount an imaging component, which improves the overall integration and miniaturization of the detection device. In this embodiment, a sequencer is used as an example for illustration.

[0074] Please see Figure 1 The detection device 100 of this embodiment includes a main support assembly 10, a stage module 20, a vibration damper 30, and an imaging assembly 40. The main support assembly 10 forms a receiving space 11. The stage module 20 is located within the receiving space 11 and can move within the receiving space 11. When the detection device 100 is placed on a work platform (e.g., a desktop or other horizontal work surface), the vibration damper 30 is supported on the lower part of the main support assembly 10; the imaging assembly 40 is connected to the main support assembly 10, located above the stage module 20, and spaced apart from the stage module 20.

[0075] The main support assembly 10 supports and mounts various functional modules within the detection device 100 (e.g., stage module 20 and imaging assembly 40). The stage module 20 carries the biological slide. The imaging assembly 40 detects information about the biological sample on the biological slide. The vibration damper 30 dampens the overall vibration of the detection device 100.

[0076] The main support assembly 10 includes a frame 12 fixedly connected to each other and a mounting plate 13 mounted on the frame 12. The frame 12 and the mounting plate 13 enclose a receiving space 11. The vibration damper 30 is supported on the side of the frame 12 away from the mounting plate 13, and the imaging assembly 40 is supported on the side of the mounting plate 13 away from the frame 12.

[0077] Please see Figure 2In this embodiment, the frame 12 has a first support plate 121, a bottom plate 122, and a second support plate 123 connected in sequence. The bottom plate 122 is a plate-like structure, opposite to and spaced apart from the mounting plate 13, and has a generally rectangular moving plane 1221. The first support plate 121 and the second support plate 123 are respectively connected to two opposite sides of the moving plane 1221 and extend toward the mounting plate 13, making the frame 12 as a whole "U" shaped. In this embodiment, the first support plate 121, the bottom plate 122, and the second support plate 123 are all castings with reinforcing ribs on the side away from the receiving space 11, or they can be assembled machined parts. The moving plane of the bottom plate 122 is a high-precision, high-flatness surface.

[0078] In this embodiment, the two opposite edges of the mounting plate 13 are fixedly mounted on the first support plate 121 and the end of the second side 122 away from the base plate 122, respectively. The mounting plate 13 is also a plate-shaped structure, forming a mounting plane 131 that is opposite to the base plate 122 and parallel to the moving plane 1221. Please refer to the following: Figure 2 and Figure 3 The detection device 100 is connected to the mounting plane 131. In this embodiment, the first support plate 121 and the second support plate 123 are respectively provided with four mounting holes 1211 and 1231 at one end of the mounting plate 13 for fixing the mounting plate 13.

[0079] In this embodiment, the mounting plate 13 also includes multiple precision-machined planes located on the mounting plane 131, serving as reference mounting surfaces 132. Each reference mounting surface 132 is provided with at least one mounting positioning hole 133. The imaging assembly 30 includes multiple functional units, and each reference mounting surface 132 is used to mount and position one of the functional units to accurately determine the position of each optical component in the functional unit in the entire optical path. The mounting plate 13 has at least one clearance notch 134 on each of the opposite sides of the first support plate 121 and the second support plate 123 to facilitate the installation, disassembly, wiring, and maintenance of the various structures integrated in the stage module 20. The mounting plate 13 also includes two reinforcing ribs 135 disposed on the mounting plane 131. The two reinforcing ribs 135 are both elongated and have different lengths to strengthen the rigid support of the mounting plate 13, ensuring that the deformation and vibration modes of the mounting plate 13 meet the equipment requirements.

[0080] Please see Figure 4 The lower surface of the mounting plate 13 (the surface facing the platform module 20) has a honeycomb-like structure, that is, it has multiple recesses 136 arranged at intervals. In this way, on the one hand, it helps to reduce the transmission of external vibrations and reduce rigid deformation, thereby avoiding the adverse effects of vibration and deformation caused by external factors or the movement of the platform module 20 on the performance of the equipment; on the other hand, it reduces the weight of the entire equipment while ensuring the rigid support of the structure.

[0081] Please refer to this again. Figure 2 and Figure 3 The vibration damper 30 is located on the side of the frame 12 away from the mounting plate 13 and is used to support the main support assembly 10. The projection of the vibration damper 30 on the two support plates (121 / 123) in a direction parallel to the bottom plate at least covers a portion of the support plates (121 / 123).

[0082] In this embodiment, the detection device 100 includes four vibration dampers 30 corresponding to the two support plates (121 / 123). The four vibration dampers 30 are arranged at intervals, with two vibration dampers 30 connected to the first support plate 121 and the other two vibration dampers 30 connected to the second support plate 123.

[0083] Each damper 30 includes four support rods 31, support feet 32, and damping components 33. The support rods 31 are connected between the support feet 32 ​​and the damping components 33. The support feet 32 ​​are bent and extended from one end of the support rods 31 and are positioned opposite to the base plate 122. The damping components 33 are directly connected to the corresponding support plates (121 or 123).

[0084] In a further embodiment, the frame 12, the stage module 20, and the imaging component 40 together form a block to be damped. Four dampers 30 are arranged around the outer periphery of the block to be damped, and the damping components 33 in each damper 30 form a damping surface. The center of the damping surface coincides with the center of gravity of the block to be damped.

[0085] Each vibration damping component 33 includes an upper base 331, a lower base 332, and a damping pad 333 sandwiched between the upper base 331 and the lower base 332. The upper base 331 is fixed to the support plate (121 or 123), and the lower base 332 is fixed to the support rod 31. The damping pad 333 may include at least one of a vibration isolator and a damper. In this embodiment, the aforementioned damping surface is formed by the top surface of the vibration damping component 33 in each of the aforementioned vibration dampers 30. That is, the top surfaces of the vibration damping components 33 in each of the aforementioned vibration dampers 30 are on the same surface, which is defined as the aforementioned damping surface.

[0086] The first support plate 121 and the second support plate 123 respectively have mounting portions 1212 and 1232 (i.e., reinforcing ribs formed on the first support plate 121 and the second support plate 123) protruding from the side away from the receiving space 11, which are fixedly connected to the upper base 331. The mounting portions 1212 and 1232 cover the end of the upper base 331 away from the vibration damping pad 333.

[0087] The detection device 100 also includes a base 50 that is opposite to and spaced apart from the base plate 122. Four vibration dampers 30 are located between the base plate 122 and the base 50 and are fixedly connected to the base 50. In this embodiment, the base 50 is a rectangular flat plate structure, and four support legs 32 are respectively fixedly connected to the four corners of the same surface of the base 50, so that the main support assembly 10 is suspended relative to the base 50, reducing vibration transmission.

[0088] The overall design of the vibration damper 30 in this embodiment can support a weight of more than 67kg, and can isolate vibration frequencies of 8HZ, 15HZ, 20HZ or 30HZ or higher according to different vibration damping requirements.

[0089] Please refer to the following: Figure 1 The stage module 20 is movably connected to the movable plane 1221 of the base plate 122. The stage module 20 includes a movable platform 21 and a slide processing device 22 integrated into the movable platform 21. The movable platform 21 is movably connected to the movable plane 1221. The movable platform 21 has a bearing surface 211 facing away from the base plate 122. The bearing surface 211 is used to bear biological slides. In this embodiment, the movable platform 21 forms two reagent kit mounting positions 212, which are symmetrically distributed. Each reagent kit mounting position 212 is a rectangular space for accommodating reagent kits, which are used to hold reaction reagents. In this embodiment, the opening 2121 of each reagent kit mounting position 212 is formed in the side plate of the movable platform 21 (perpendicular to the movable plane 1221) and faces the direction where the first support plate 121 and the second support plate 123 are not provided, so as to pick up and put down the reagent kit. The slide processing device 22 is used to load the reaction reagents in the reagent kit onto the biological slide for optical detection.

[0090] The two opposite edges of the moving plane 1221, not connected to the first support plate 121 and the second support plate 123, extend along the X direction. The two opposite edges of the moving plane 1221 connected to the first support plate 121 and the second support plate 123 extend along the Y direction, with the X direction perpendicular to the Y direction. The moving platform 21 can translate within the receiving space 11 (i.e., on the moving plane 1221) along the X and Y directions respectively. When the bearing surface 211 carries the biological slide and the reagent kit mounting position 212 contains the reagent kit, the moving platform 21 can synchronously translate the biological slide, the reagent kit, and the slide processing device.

[0091] In this embodiment, the mobile platform 21 uses a high-speed linear motor (not shown) to achieve high-speed movement in the X and Y directions. The control precision of the motor speed and the positioning precision during the movement can both reach the nanometer level.

[0092] Please see Figure 5Imaging component 40 emits a laser as excitation light toward stage module 20. A biological slide on stage module 20 carries a biological sample. Biomarkers in the biological sample carry fluorescent groups. These fluorescent groups are excited by the excitation light to produce fluorescence. Imaging component 30 also collects the fluorescence to obtain information about the biological sample (biomarker content, biomarker distribution, etc.).

[0093] Please refer to the following: Figure 5 and Figure 6 The imaging assembly 40 includes a light source 41, an objective lens module 42, a sensor module 43, and a light guiding device 44. The light guiding device 44 is located between the objective lens module 42 and the sensor module 43, and is situated at the end of the objective lens module 42 facing away from the stage module 20. It is optically connected to both the objective lens module 42 and the sensor module 43. The light source 41, the sensor module 43, and the light guiding device 44 are connected to the mounting plane 131 of the mounting plate 13. The objective lens module 42 penetrates the mounting plate 13 and partially extends into the receiving space 11. The orthographic projections of the sensor module 43 and the objective lens module 42 on the mounting plate 13 do not overlap.

[0094] The sensor module 43 includes a first imaging channel 431, a second imaging channel 432, and a focusing module 433. The light guiding device 44 has multiple sides perpendicular to the mounting plate 13, at least two of which are parallel and at least two are perpendicular to each other. The light source 41, objective lens module 42, first imaging channel 431, second imaging channel 432, and focusing module 433 are optically connected to the light guiding device 44 through one side of the light guiding device 44 to form a complete optical path structure. In this embodiment, the orthographic projections of the first imaging channel 431 and the second imaging channel 432 on the mounting plate 13 do not overlap, and the orthographic projection of the focusing module 433 on the mounting plate 13 is located between the orthographic projections of the first imaging channel 431 and the second imaging channel 432 on the mounting plate 13.

[0095] The focusing module 433 is optically connected to the side of the light guiding device 44 opposite to the mounting plate 13, that is, the light guiding device 44 is located between the focusing module 433 and the mounting plate 13. In this embodiment, the focusing module 433 includes a support frame 4331 and a focuser 4332. The support frame 4331 is fixed on the mounting plane 131 on the mounting plate 13, and the focuser 4332 is supported by the support frame 4331, so that the focuser 4332 is suspended relative to the mounting plate 13 and located above the light guiding device 44. The height of the focuser 4332 relative to the mounting plate 13 is greater than the height of the first imaging channel 431 and the second imaging channel 432, so that the focuser 4332 is also located above the first imaging channel 431 and the second imaging channel 432, avoiding the first imaging channel 431 and the second imaging channel 432. In this way, the mounting method of the focusing module 433 effectively utilizes the height space of the detection device 100, making the detection device 100 more integrated.

[0096] In this embodiment, the imaging assembly 40 further includes a driver 45 connected to the objective lens module 42 and mounted on the mounting plate 13. The driver 45 includes a stator 451 fixed on the mounting plane of the mounting plate 13 and a mover 452 penetrating the mounting plate 13 and connected to the objective lens module 42. The mover 452 allows the objective lens module 42 to be movably disposed relative to the mounting plate 13 (translated along the optical axis of the objective lens). The projection of the driver 45 onto the mounting plate 13 does not overlap with that of the sensor module 43.

[0097] Light source 41 is used to emit the excitation light. Focusing module 433 is used to emit the focusing beam. Objective lens module 42 is used to focus the excitation light and the focusing beam onto the biological slide, and to collect the laser beam generated by the biological sample and the reflected focusing beam. The laser beam includes a first fluorescence signal and a second fluorescence signal of different wavelengths. First imaging channel 431 is used to sense the first fluorescence signal, and second imaging channel 332 is used to sense the second fluorescence signal. Light guiding device 44 is used to separate the optical paths of the laser beam and the focusing beam, and also to separate the optical paths of the first fluorescence signal and the second fluorescence signal in the laser beam.

[0098] In this embodiment, the optical axes of the first imaging channel 431 and the second imaging channel 432 are perpendicular to each other and parallel to the mounting plate 13. The first imaging channel 431 and the second imaging channel 432 have essentially the same structure and function. The first imaging channel 431 includes a first tube lens 4311 and a first image sensor 4312, and the second imaging channel 432 includes a second tube lens 4321 and a second image sensor 4322. The first image sensor 4312 is used to sense a first fluorescence signal, and the second image sensor 4322 is used to sense a second fluorescence signal.

[0099] The detection device 100 described in this embodiment includes a fixedly connected frame 12 and mounting plate 13. The frame 12 and mounting plate 13 house the stage module 20 and the imaging assembly 40, which improves the overall integration and miniaturization of the detection device 100, facilitating transportation, installation, and optical detection operations. Furthermore, the reagent kit and slide processing device are integrated into the stage module 20, eliminating the need for additional installation space and improving space utilization.

[0100] Those skilled in the art should recognize that the above embodiments are only used to illustrate this application and are not intended to limit this application. Any appropriate changes and variations made to the above embodiments within the essential spirit and scope of this application fall within the scope of protection claimed by this application.

Claims

1. A detection device, characterized in that, It includes a frame and a mounting plate that are fixedly connected, the frame and the mounting plate enclosing a receiving space; The containment space contains a stage module, and the mounting plate is positioned opposite to and spaced apart from the stage module. An imaging component is supported on the side of the mounting plate away from the stage module. The frame includes a base plate that is opposite to and spaced apart from the mounting plate, and support plates that extend from opposite sides of the base plate toward the mounting plate. The platform module is supported by the base plate. The imaging assembly includes an objective lens module that penetrates the mounting plate and extends into the receiving space, and a sensor module optically connected to the objective lens module; the orthographic projections of the sensor module and the objective lens module on the mounting plate do not overlap. The detection device further includes a vibration damper connected to the support plate and supporting the frame, wherein the projection of the vibration damper on the support plate along a direction parallel to the bottom plate at least covers a portion of the support plate.

2. The detection device as described in claim 1, characterized in that, The vibration damper includes a support rod corresponding to the support plate and a vibration damping component connected between the support rod and the support plate; the detection device includes multiple vibration dampers, the frame, the stage module, and the imaging component together form a block to be damped, the multiple vibration dampers surround the outer periphery of the block to be damped, and the vibration damping components of each vibration damper form a damping surface, the center of the damping surface coincides with the center of gravity of the block to be damped.

3. The detection device as described in claim 2, characterized in that, Each of the vibration dampers further includes a support foot that bends and extends from one end of the support rod and is disposed opposite to the base plate; the vibration damping assembly includes an upper base, a lower base, and a vibration damping pad sandwiched between the upper base and the lower base, the upper base being fixed to the support plate, and the lower base being fixed to the support rod.

4. The detection device as described in claim 3, characterized in that, The vibration damping pad includes at least one of a vibration isolator and a damper.

5. The detection device as described in claim 3, characterized in that, The support plate protrudes from the side opposite to the receiving space to form a mounting part that is fixed to the upper base, and the mounting part covers the end of the upper base away from the vibration damping pad.

6. The detection device as described in claim 3, characterized in that, The detection device also includes a base that is opposite to and spaced apart from the base plate, and the support foot is located between the base plate and the base and is fixed to the base.

7. The detection device as described in claim 1, characterized in that, The imaging assembly includes a light guiding device located between the objective lens module and the sensor module. The light guiding device is located at the end of the objective lens module away from the stage module and is optically connected to both the objective lens module and the imaging assembly.

8. The detection device as described in claim 7, characterized in that, The sensor module includes a first imaging channel and a second imaging channel, each of which includes an image sensor that collects light signals of different wavelengths; the first imaging channel and the second imaging channel are respectively connected to different sides of the light guiding device that are parallel to the mounting plate and their orthogonal projections on the mounting plate do not overlap.

9. The detection device as described in claim 8, characterized in that, The sensor module also includes a focusing module optically connected to the light guiding device, wherein the orthographic projection of the focusing module on the mounting plate is at least partially located between the first imaging channel and the second imaging channel.

10. The detection device as described in claim 9, characterized in that, The focusing module is optically connected to the side of the light guiding device away from the mounting plate, and includes: a support frame fixed on the mounting plate, and a focuser supported by the support frame, wherein the height of the focuser relative to the mounting plate is greater than that of the first imaging channel and the second imaging channel.

11. The detection device as described in claim 9, characterized in that, The imaging assembly further includes a driver connected to the objective lens module and mounted on the mounting plate. The driver includes a stator fixed to the mounting plate and a mover passing through the mounting plate and connected to the objective lens module. The mover drives the objective lens module to be movably positioned relative to the mounting plate. The projection of the driver on the mounting plate does not overlap with the sensor module.

12. A sequencer, characterized in that, Includes the detection device as described in any one of claims 1-11.

Images