Detection kit with good sealing effect
By employing a multi-seal structure and compression design in the test kit, the problem of poor sealing effect has been solved, achieving higher sealing performance and experimental accuracy, simplifying operation, and improving work efficiency.
Patent Information
- Application Number
- CN202520271786.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-02-20
- Publication Date
- 2025-12-05
- Estimated Expiration
- 2035-02-20
AI Technical Summary
Existing test kits have poor sealing properties, allowing external impurities to enter and affecting the accuracy and reliability of test results.
Employing a multi-layered sealing structure and compression design, including a combination of sealing strips and compression strips, the kit ensures a multi-layered seal when closed, preventing sample and reagent leakage.
The improved sealing performance of the reagent kit ensures the accuracy and safety of the experiment, simplifies the operation process, and improves work efficiency.
Smart Images
Figure CN223632162U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to detection kit technical field especially relates to sealed effectual detection kit. BACKGROUND
[0002] High-throughput sequencing technology is a technology that can simultaneously sequence a large number of DNA or RNA molecules, which can quickly and efficiently determine nucleic acid sequences and obtain massive genetic information, and plays an important role in the research and diagnosis of brain glioma. Brain glioma is a tumor originating from brain glial cells, which is the most common primary intracranial tumor, and has the characteristics of strong invasiveness, high heterogeneity, and great difficulty in treatment. Using high-throughput sequencing technology to detect brain glioma can comprehensively analyze the genomic and transcriptomic information of tumor cells, helping doctors to deeply understand the molecular characteristics of the tumor, such as discovering gene mutations and gene expression changes related to the occurrence and development of brain glioma, which is helpful for precise typing, prognosis evaluation, and guiding the development of individualized treatment plans, and provides strong support for improving the treatment effect of brain glioma and the quality of life of patients.
[0003] When high-throughput sequencing technology is used to detect brain glioma, tumor tissue, cerebrospinal fluid, or blood samples are collected, and then reagents are used to extract DNA and RNA from the samples using phenol-chloroform method, magnetic bead method, etc. The extracted nucleic acid fragments are fragmented and connected to specific adapter sequences to construct a library, which is stored in a specific buffer and then added to a high-throughput sequencer. Large-scale parallel sequencing is performed using techniques such as sequencing by synthesis, and finally the raw data obtained by sequencing is analyzed using bioinformatics, including removing low-quality data, aligning to the reference genome, and detecting variations, to identify molecular characteristics related to brain glioma. During the entire process, nucleic acid extraction kits, library construction kits, etc. contain various buffers, enzymes, primers, and other reagents to ensure the smooth progress of the detection steps.
[0004] However, some existing detection kits cannot effectively ensure the sealing effect of the box. Once the sealing of the kit is insufficient, impurities such as air, moisture, and microorganisms from the outside world can easily enter the box and react with the detection reagents in the kit, changing the chemical composition and activity of the reagents, ultimately leading to deviations in the detection results, and thus producing false positive or false negative errors, greatly affecting the accuracy and reliability of the detection, and causing many misleading and obstacles to subsequent diagnosis, prevention, and other work. Therefore, in view of the above shortcomings, a detection kit with good sealing effect is proposed to solve the above problems. UTILITY MODEL CONTENTS
[0005] In order to make up for the above shortcomings, the utility model provides a detection kit with good sealing effect, aiming to improve the problem that some detection kits in the prior art cannot effectively ensure the sealing effect of the box.
[0006] In order to achieve the above object, the utility model adopts the following technical scheme:
[0007] The utility model discloses a detection kit with good sealing effect, which comprises a box body, two hinges are fixedly connected to the rear side of the box body, a top cover is fixedly connected to the front side of the two hinges, two side plates are fixedly connected to the top of the box body, a sealing strip one is fixedly connected to the side of the two side plates, a sealing groove one is formed in the front side of the box body, an extrusion strip one is formed in the inside front side of the box body, a sealing strip two is fixedly connected to the bottom of the top cover, two extrusion strip twos are fixedly connected to the inside of the top cover, a sealing groove two is formed in the inside left and right sides of the top cover, and a docking assembly is arranged on the front side of the top cover.
[0008] As a further description of the above technical scheme:
[0009] The docking assembly comprises a clamping plate, the rear side of the clamping plate is fixedly connected to the front side of the top cover, an arc-shaped groove is formed in the inside of the clamping plate, a groove is formed in the inside of the clamping plate, a rotating disc is rotatably connected to the inside of the box body, a rotating rod is fixedly connected to the front side of the rotating disc, a rotating convex disc is fixedly connected to the front side of the rotating rod, and two elastic clamping balls are fixedly connected to the rear side of the rotating convex disc.
[0010] As a further description of the above technical scheme:
[0011] The outside of the sealing strip two is slidably connected to the inside of the sealing groove one, and the outside of the extrusion strip one is in contact with the bottom of the sealing strip two.
[0012] As a further description of the above technical scheme:
[0013] The outside of the sealing strip one is slidably connected to the inside of the sealing groove two, and the outside of the sealing strip one is in contact with the outside of the extrusion strip two.
[0014] As a further description of the above technical scheme:
[0015] The outside of the top cover is slidably connected to the side of the two side plates, and the bottom of the top cover is in contact with the top of the box body.
[0016] As a further description of the above technical scheme:
[0017] The outside of the rotating convex disc is slidably connected to the inside of the clamping plate, and the outside of the rotating rod is rotatably connected to the inside of the clamping plate.
[0018] As a further description of the above technical scheme:
[0019] The elastic clamping ball is externally and slidably connected in the groove, and the elastic clamping ball is externally and slidably connected on the front side of the clamping plate.
[0020] Further description of the above technical solution is as follows:
[0021] The rotating rod is externally and rotatably connected in the box body, and the extrusion strip one is externally and fixedly connected in the sealing groove one.
[0022] The utility model has the advantages of the following beneficial effects:
[0023] 1. When the reagent box is closed, the sealing strip two slides into the sealing groove one, the extrusion strip one applies pressure to the sealing strip two, the sealing strip two is tightly filled in the sealing groove one, at the same time, the sealing strip one slides into the sealing groove two, the extrusion strip two extrudes the sealing strip one, and the sealing strip one is tightly filled in the sealing groove two.
[0024] 2. When the reagent box is opened, the rotating convex disc is rotated, the rotating rod and the rotating disc are driven to rotate, the elastic clamping ball slides out of the groove, the rotating convex disc is aligned with the arc-shaped groove, then the top cover is rotated, the rotating convex disc slides out of the clamping plate, and the reagent box can be opened. BRIEF DESCRIPTION OF DRAWINGS
[0025] Figure 1 A perspective view of the reagent box with good sealing effect is provided for the utility model;
[0026] Figure 2 A top cover structure schematic view of the reagent box with good sealing effect is provided for the utility model;
[0027] Figure 3 A side plate structure schematic view of the reagent box with good sealing effect is provided for the utility model;
[0028] Figure 4 For Figure 3 An enlarged view of A in the utility model.
[0029] LEGEND:
[0030] 1, box body; 2, hinge; 3, top cover; 4, side plate; 5, sealing strip one; 6, sealing groove one; 7, extrusion strip one; 8, sealing strip two; 9, extrusion strip two; 10, sealing groove two; 11, clamping plate; 12, arc-shaped groove; 13, groove; 14, rotating disc; 15, rotating rod; 16, rotating convex disc; 17, elastic clamping ball. DETAILED DESCRIPTION
[0031] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the utility model.
[0032] With reference to Figures 1 to 3 The utility model provides an embodiment: reagent test kit that sealed effect is good, including box body 1, box body 1 is as the main body bearing structure of reagent test kit. The rear side fixed connection of box body 1 has two hinges 2, the front side fixed connection of two hinges 2 has top cover 3, and the bottom of top cover 3 is in contact with the top of box body 1, and top cover 3 cooperates with box body 1 and constitutes the sealed space jointly. The top of box body 1 is fixedly connected with two side plates 4, and the outside of top cover 3 is slidably connected on the proximal side of the two side plates 4, and the side plate 4 plays the role of guiding and auxiliary sealing. The proximal side of the two side plates 4 is fixedly connected with sealing strip one 5, and the elasticity of sealing strip one 5 can be deformed when being extruded, filling the gap, thereby improving the sealing effect. The front side of box body 1 is provided with sealing groove one 6, and the inside front side of box body 1 is provided with extrusion strip one 7, and the outside of extrusion strip one 7 is fixedly connected in the inside of sealing groove one 6, and the bottom of top cover 3 is fixedly connected with sealing strip two 8;
[0033] The outside of sealing strip two 8 is slidably connected in the inside of sealing groove one 6, and the outside of extrusion strip one 7 is in contact with the bottom of sealing strip two 8, and extrusion strip one 7 can be in contact with the bottom of sealing strip two 8, and uniformly exert pressure, so that sealing strip two 8 can fully fill sealing groove one 6, and the sealing effect is improved. The inside of top cover 3 is fixedly connected with two extrusion strips two 9, and extrusion strip two 9 is used for extruding sealing strip one 5 when the reagent test kit is closed. The outside of sealing strip one 5 is in contact with the outside of extrusion strip two 9, and the inside of top cover 3 is provided with sealing groove two 10 on the left and right sides, and the outside of sealing strip one 5 is slidably connected in the inside of sealing groove two 10, and sealing groove two 10 cooperates with sealing strip one 5 to realize sealing. The front side of top cover 3 is provided with a docking assembly for docking.
[0034] With reference to Figures 2 to 4The docking assembly comprises a clamping plate 11, the rear side of the clamping plate 11 is fixedly connected to the front side of the top cover 3, an arc-shaped slot 12 is formed in the interior of the clamping plate 11, the arc-shaped slot 12 can smoothly slide the rotating convex disc 16 therein and can ensure the stability of the rotating convex disc 16 during the sliding process. A recess 13 is formed in the interior of the clamping plate 11, the recess 13 is matched with the elastic clamping balls 17 to realize the positioning of the rotating convex disc 16. A rotating disc 14 is rotatably connected to the interior of the box body 1, a rotating rod 15 is fixedly connected to the front side of the rotating disc 14, the rotating rod 15 and the rotating convex disc 16 are driven by rotation. The rotating rod 15 is rotatably connected to the interior of the box body 1, the rotating convex disc 16 is fixedly connected to the front side of the rotating rod 15, the rotating convex disc 16 is slidably connected to the interior of the clamping plate 11, two elastic clamping balls 17 are fixedly connected to the rear side of the rotating convex disc 16, the elastic clamping balls 17 are slidably connected to the interior of the recess 13, the elastic clamping balls 17 are slidably connected to the front side of the clamping plate 11, when the elastic clamping balls 17 slide into the recess 13, due to the elasticity, a certain elastic force is generated to lock the rotating convex disc 16 at a specific position to prevent accidental rotation. When it is needed to open the reagent box, the rotating convex disc 16 is rotated to make the elastic clamping balls 17 slide out of the recess 13, so that the rotating convex disc 16 can be freely rotated.
[0035] Working principle: when the reagent box is used, the rotating convex disc 16 is first rotated to drive the rotating rod 15 and the rotating disc 14 to rotate, at this time, the elastic clamping balls 17 slide out of the interior of the recess 13, so that the rotating convex disc 16 is aligned with the interior of the arc-shaped slot 12, then the top cover 3 is rotated to make the rotating convex disc 16 slide out of the interior of the clamping plate 11, so that the reagent box is conveniently opened and closed, then the sample and the reagent are placed in the reagent box, then the reagent box is closed again, and the above steps are reversely operated to realize the closing of the reagent box, when the reagent box is closed, the sealing strip two 8 slides into the interior of the sealing groove one 6, the pressing strip one 7 presses the sealing strip two 8, so that the sealing strip two 8 can fill the sealing groove one 6 more tightly, at the same time, the sealing strip one 5 slides into the interior of the sealing groove two 10 and the pressing strip two 9 presses the sealing strip one 5, so that the sealing strip one 5 can fill the interior of the sealing groove two 10 more tightly, so that the sealing effect is greatly improved.
[0036] Finally, it should be noted that: the above only describes the preferred embodiments of the present application and is not intended to limit the present application, although the present application has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions recorded in the foregoing embodiments or make equivalent replacement for some technical features, any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present application shall be included in the protection scope of the present application.
Claims
1. A test kit with a good sealing effect, comprising a box body (1), characterized in that: The rear side of the box body (1) is fixedly connected with two hinges (2), the front side of the two hinges (2) is fixedly connected with a top cover (3), the top of the box body (1) is fixedly connected with two side plates (4), the side close to each other of the two side plates (4) is fixedly connected with a sealing strip one (5), the front side of the box body (1) is provided with a sealing groove one (6), the inside front side of the box body (1) is provided with an extrusion strip one (7), the bottom of the top cover (3) is fixedly connected with a sealing strip two (8), the inside of the top cover (3) is fixedly connected with two extrusion strip two (9), the inside left and right sides of the top cover (3) are provided with a sealing groove two (10), and the front side of the top cover (3) is provided with a docking assembly for docking.
2. The test kit with a good sealing effect according to claim 1, characterized in that: The rear side of the box body (1) is fixedly connected with two hinges (2), the front side of the two hinges (2) is fixedly connected with a top cover (3), the top of the box body (1) is fixedly connected with two side plates (4), the side close to each other of the two side plates (4) is fixedly connected with a sealing strip one (5), the front side of the box body (1) is provided with a sealing groove one (6), the inside front side of the box body (1) is provided with an extrusion strip one (7), the bottom of the top cover (3) is fixedly connected with a sealing strip two (8), the inside of the top cover (3) is fixedly connected with two extrusion strip two (9), the inside left and right sides of the top cover (3) are provided with a sealing groove two (10), and the front side of the top cover (3) is provided with a docking assembly for docking.
3. The test kit with a good sealing effect according to claim 1, characterized in that: The outside of the sealing strip two (8) is slidably connected in the inside of the sealing groove one (6), and the outside of the extrusion strip one (7) is in contact with the bottom of the sealing strip two (8).
4. The test kit with a good sealing effect according to claim 1, characterized in that: The outside of the sealing strip one (5) is slidably connected in the inside of the sealing groove two (10), and the outside of the sealing strip one (5) is in contact with the outside of the extrusion strip two (9).
5. The sealed test kit of claim 1, wherein: The outside of the top cover (3) is slidably connected on the side close to each other of the two side plates (4), and the bottom of the top cover (3) is in contact with the top of the box body (1).
6. The sealed test kit of claim 2, wherein: The outside of the rotating convex disc (16) is slidably connected in the inside of the clamping plate (11), and the outside of the rotating rod (15) is rotatably connected in the inside of the clamping plate (11).
7. The sealed test kit of claim 2, wherein: The outside of the elastic clamping ball (17) is slidably connected in the inside of the groove (13), and the outside of the elastic clamping ball (17) is slidably connected on the front side of the clamping plate (11).
8. The sealed test kit of claim 2, wherein: The outside of the rotating rod (15) is rotatably connected in the inside of the box body (1), and the outside of the extrusion strip one (7) is fixedly connected in the inside of the sealing groove one (6).