Novel cell culture bag support
By designing an adjustable elastic tray and telescopic rod structure, the problem of fixed tray size in existing systems was solved, enabling adaptability to cell culture bags of different specifications, improving the stability and permeability of cell culture, and enhancing the culture quality of immune cells.
Patent Information
- Application Number
- CN202423144068.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-19
- Publication Date
- 2025-12-05
- Estimated Expiration
- 2034-12-19
AI Technical Summary
The current immune cell culture trays have a fixed size and cannot accommodate cell culture bags of different sizes, resulting in a limited range of applications and affecting the convenience of immune cell culture work.
An adjustable elastic tray and telescopic rod structure was designed. The length or width of the elastic tray can be expanded by the telescopic rod to adapt to cell culture bags of different sizes, and the culture bags can be fixed by elastic ropes to ensure their stability and air permeability.
This expands the applicability of cell culture scaffolds, ensures the stability and permeability of cell culture bags, and improves the quality and efficiency of immune cell culture.
Smart Images

Figure CN223633383U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to cell culture technical field especially relates to a novel cell culture bag support. BACKGROUND
[0002] With the growth of age, the immune function of human body gradually weakens, which leads to that the number and activity of immune cells in the crowd of about 50 years old are only about half of that when they are 20 years old. This attenuation significantly reduces the body's ability to resist disease and increases the risk of illness. In order to cope with this challenge, immune cell therapy emerges as a new treatment method and has obtained rapid development and wide application in the medical field.
[0003] Immune cell therapy collects patients' own immune cells, amplifies and activates them in a laboratory environment, so that they have stronger targeting and killing ability, and then reinfuses these treated cells into patients to achieve the purpose of resisting disease.
[0004] Successful immune cell therapy depends on effective in vitro cell culture process. In this process, immune cells usually grow in a semi-suspended manner, and the formation of cell clusters is crucial to promote rapid cell proliferation. Due to its soft material, the traditional cell culture bag is prone to shaking in daily operation, which may lead to the dispersion of cell clusters, thereby seriously affecting the number and activity of immune cells finally cultured. Therefore, using a tray to constrain the culture bag to ensure that the cells grow in a more stable and favorable environment has become one of the key factors to improve the efficiency and technical success of in vitro culture of immune cells.
[0005] The utility model with publication (announcement) No. CN208308876U discloses a culture tray matched with immune cell culture bag, which provides support and protection for cell culture bag and can be used for in vitro culture of immune cells.
[0006] As the above technical solution, the size of the existing immune cell culture tray is generally fixed, and the size of the tray cannot be flexibly adjusted according to different specifications of cell culture bags, which leads to that the existing immune cell culture tray has a smaller applicable range and affects the convenience of immune cell culture work. UTILITY MODEL CONTENT
[0007] Therefore, the utility model provides a novel cell culture bag support, which adjusts the plate width of the elastic tray to adapt to the change of the size of the cell culture bag, improves the applicable range of the support, provides convenience for the culture work of immune cells, and solves the problem that the existing immune cell culture tray has a smaller applicable range and affects the convenience of immune cell culture work.
[0008] The technical scheme of the utility model is implemented as follows:
[0009] The utility model provides a novel cell culture bag support, including elastic tray, still include telescopic link and support leg, wherein,
[0010] The elastic tray is rectangular, each of four side ends of the elastic tray is provided with a telescopic link, and the telescopic link is used for expanding the length or width of the elastic tray;
[0011] Four telescopic links are horizontally arranged and connected at the head and tail to form a frame.
[0012] The support leg is provided with one at each of four corners of the frame.
[0013] On the basis of the above technical scheme, preferably, a culture bag placing groove is formed between the elastic tray and the frame.
[0014] On the basis of the above technical scheme, preferably, the telescopic link includes left and right spiral screws and an outer sleeve, wherein,
[0015] The two ends of the left and right spiral screws are respectively screwed with an outer sleeve;
[0016] The end of the outer sleeve away from the left and right spiral screws is fixedly connected with the support leg;
[0017] The side of the outer sleeve is fixedly connected with the side end of the elastic tray.
[0018] On the basis of the above technical scheme, preferably, a knob part is arranged on the middle part of the left and right spiral screws.
[0019] On the basis of the above technical scheme, preferably, the elastic tray is arranged as an elastic rubber plate, and a plurality of air holes are arranged on the elastic tray in the vertical direction.
[0020] On the basis of the above technical scheme, preferably, the elastic tray is arranged as an elastic net.
[0021] On the basis of the above technical scheme, preferably, further comprising an elastic rope, wherein,
[0022] A plurality of elastic ropes are arranged above the elastic tray and used for fixing the culture bag placed in the culture bag placing groove;
[0023] The two ends of the elastic rope are detachably arranged on the frame.
[0024] On the basis of the above technical scheme, preferably, a hook part is arranged on the two ends of the elastic rope, wherein,
[0025] The hook part is hung on the side of the telescopic rod.
[0026] On the basis of the above technical scheme, preferably, the plurality of elastic ropes are arranged in parallel or cross.
[0027] On the basis of the above technical scheme, preferably, the upper end of the supporting leg is provided with a plug part, and the lower end is provided with a slot part.
[0028] The inner diameter of the plug part is greater than or equal to the outer diameter of the slot part.
[0029] The novel cell culture bag support has the following beneficial effects relative to the prior art:
[0030] (1) The telescopic rod is arranged to expand the length or width of the elastic tray, so that the width of the elastic tray is adjustable, and thus the support can better adapt to the size change of the cell culture bag, improve the application range of the support, and provide convenience for the culture work of immune cells.
[0031] (2) The elastic tray is arranged as an elastic rubber plate, and a plurality of air holes are arranged on the elastic tray in the vertical direction, or the elastic tray is arranged as an elastic net, so that the elastic tray has good air permeability to promote gas exchange and ensure the healthy growth of cells.
[0032] (3) The telescopic rod comprises left and right screw rods and a sleeve tube, and a knob part is arranged on the middle part of the left and right screw rods, so that the telescopic rod can be conveniently expanded and contracted, and thus the width of the elastic tray can be conveniently adjusted.
[0033] (4) The elastic rope is arranged to fix the culture bag placed in the culture bag placing groove, so that the culture bag can be conveniently fixed, and displacement or shaking of the culture bag during the culture process is avoided, and the culture quality is improved.
[0034] (5) The plug part is arranged at the upper end of the supporting leg, and the slot part is arranged at the lower end, so that the support can be conveniently used in multiple layers, and is more practical. BRIEF DESCRIPTION OF DRAWINGS
[0035] In order to more clearly illustrate the technical scheme in the embodiments of the present application or the prior art, the drawings needed in the description of the embodiments or the prior art will be briefly introduced. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative labor.
[0036] Figure 1A perspective view of the novel cell culture bag support of the utility model;
[0037] Figure 2 A side view of the elastic rope of the utility model;
[0038] Figure 3 A plan view of the novel cell culture bag support of the utility model;
[0039] Figure 4 A structure schematic view of the superimposed state of the novel cell culture bag support of the utility model;
[0040] In the figure: 1, elastic tray; 2, frame; 3, support leg; 4, elastic rope; 21, telescopic rod; 101, air hole; 201, culture bag placing groove; 211, left and right screw screw; 212, outer sleeve; 301, plug part; 302, slot part; 401, hook part; 21101, knob part. DETAILED DESCRIPTION
[0041] The technical solutions in the utility model will be clearly and completely described below in combination with specific implementation manners of the utility model. Apparently, the described implementation manners are only part of the implementation manners of the utility model, instead of all the implementation manners. Based on the implementation manners in the utility model, all other implementation manners obtained by those skilled in the art without creative labor fall within the protection scope of the utility model.
[0042] As Figures 1-4 shown, the novel cell culture bag support of the utility model comprises an elastic tray 1, a frame 2 and a support leg 3.
[0043] Among them, the elastic tray 1 is in a rectangular shape, and one telescopic rod 21 is arranged on each of the four side ends of the elastic tray 1, and the telescopic rod 21 is used to expand the length or width of the elastic tray 1; the four telescopic rods 21 are horizontally arranged and connected at the head and tail to form the frame 2; one support leg 3 is arranged at each of the four corners of the frame 2.
[0044] The support leg 3 is vertically arranged and is used to support the frame 2, so that the elastic tray 1 is suspended, and the top of the suspended elastic tray 1 is used to place a bacterial culture bag. When the size of the bacterial culture bag to be placed is large, the telescopic rod 21 is stretched to expand the width of the elastic tray 1, that is, the length and width of the elastic tray 1 are increased by stretching the four telescopic rods 21, so that the placement requirement of the large-size bacterial culture bag is met.
[0045] In addition, the support leg 3 is any one of the folding support rods in the prior art, such as the foldable support rod disclosed in CN206947495U. As Figure 1As shown, the upper half of the support leg 3 can be folded and placed above the frame 2, and the lower half can be folded and placed below the frame 2, so as to facilitate the storage of the device.
[0046] In the above structure, the longer the telescopic rod 21 is stretched, the larger the length and width of the elastic tray 1, and vice versa. According to the actual size of the bacterial culture bag, the width of the elastic tray 1 is adjusted to an appropriate size.
[0047] As shown in the drawings, Figure 1 As shown, a culture bag placing groove 201 is formed between the elastic tray 1 and the frame 2. Specifically, the edge of the elastic tray 1 is fixedly connected to the bottom surface of the frame 2. After the two are fixedly connected, the frame 2 forms the outer edge of the elastic tray 1, which restricts the bacterial culture bag from sliding off the elastic tray 1.
[0048] As shown in the drawings, Figure 3 As shown, the telescopic rod 21 includes left and right screw rods 211 and outer sleeves 212. The two ends of the left and right screw rods 211 are respectively screwed with an outer sleeve 212, and a knob part 21101 is arranged on the middle part of the left and right screw rods 211. The end of the outer sleeve 212 away from the left and right screw rods 211 is fixedly connected with the support leg 3, and the side of the outer sleeve 212 is fixedly connected with the side end of the elastic tray 1. Specifically, when the support leg 3 is a folding support rod, it includes upper, middle and lower support rods, and one end of the outer sleeve 212 is fixedly connected with the middle support rod.
[0049] The knob part 21101 is a multi-prism structure. When the length of the telescopic rod 21 needs to be adjusted, the left and right screw rods 211 are rotated through the knob part 21101. During the process, the two outer sleeves 212 on the left and right screw rods 211 are moved closer to or farther away from each other to achieve length adjustment. The knob part 21101 is a multi-prism structure. During the adjustment process, first adjust the two telescopic rods 21 that are parallel to each other, and then adjust the other two telescopic rods 21 to facilitate the adjustment operation.
[0050] The above-mentioned elastic tray 1 is provided as an elastic rubber plate or an elastic net. When the elastic tray 1 is an elastic rubber plate, as shown in the drawings, Figure 1 As shown, a plurality of air holes 101 are arranged vertically on the elastic tray 1, which are used for air permeation at the bottom of the bacterial culture bag to promote gas exchange and ensure the healthy growth of cells.
[0051] When the elastic tray 1 is an elastic net, as shown in the drawings, Figure 3 As shown, the elastic tray 1 is woven by a plurality of elastic rope bodies, and the mesh holes are prismatic or other geometric shapes, and the mesh holes have the same effect as the air holes 101.
[0052] In actual application, as shown in the drawings, Figure 1As shown, several elastic ropes 4 are arranged above the elastic tray 1, which are used to fix the culture bag placed in the culture bag placing groove 201, prevent the culture bag from shaking or moving, and effectively improve the cell quantity and activity.
[0053] Wherein, the two ends of the elastic rope 4 are detachably arranged on the frame 2, and specifically, the two ends of the elastic rope 4 are provided with hook parts 401, when the bacterial culture bag is placed in the culture bag placing groove 201, the hook parts 401 are hung on the side of the telescopic rod 21, so that the elastic rope 4 is pressed on the top of the bacterial culture bag, and the fixing of the bacterial culture bag is realized.
[0054] When the bacterial culture bag is fixed, the elastic ropes 4 can be arranged in parallel or cross. When the bacterial culture bag needs to be taken out, the hook parts 401 are detached from the telescopic rod 21. In order to facilitate the cross installation of the elastic rope 4, a plurality of ring grooves are arranged on the outer pipe wall of the outer sleeve 212, the hook parts 401 are hung in the ring grooves, and the displacement of the hook parts 401 is limited by the ring grooves, wherein the ring grooves and the cross elastic rope 4 are not drawn in the drawing.
[0055] In addition, the upper end of the supporting leg 3 is provided with a plug part 301, and the lower end is provided with a slot part 302. Wherein, the inner diameter of the plug part 301 is greater than or equal to the outer diameter of the slot part 302. Figure 4 As shown, through the structure, the stacking use of the two above-mentioned cell culture bag supports can be realized, and when stacking, the slot part 302 of the upper support is inserted into the plug part 301 of the lower support, so as to form effective support and improve the stability of the upper support.
[0056] In addition, the supporting leg 3 in the above-mentioned support can also be a common supporting rod structure, that is, the supporting leg 3 does not have folding ability, and one of the structures is selected according to actual needs.
[0057] The use method of the novel cell culture bag support of the present application is as follows:
[0058] Before using the support, the support is sterilized, and after sterilization, it is placed in a clean bench; according to the size of the culture bag, the telescopic rod 21 is stretched, and the elastic tray 1 is adjusted to the appropriate size; the cell culture bag is placed on the elastic tray 1, and the elastic rope 4 is installed on the top of the cell culture bag, and then the related experimental operation is carried out.
[0059] The above only describes the preferred embodiment of the present application, and is not used to limit the present application, and any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application.
Claims
1. A novel cell culture bag holder comprising an elastic tray (1), characterized in that: It also comprises telescopic rods (21) and supporting legs (3), wherein, The elastic tray (1) is rectangular, and each of the four side ends of the elastic tray (1) is provided with a telescopic rod (21) for expanding the length or width of the elastic tray (1). The four telescopic rods (21) are horizontally arranged and connected at the head and tail to form a frame (2). Each of the four corners of the frame (2) is provided with a supporting leg (3).
2. A novel cell culture bag holder according to claim 1, characterized in that: A culture bag placing groove (201) is formed between the elastic tray (1) and the frame (2).
3. A novel cell culture bag holder according to claim 2, characterized in that: The telescopic rod (21) comprises left and right spiral screws (211) and an outer sleeve (212), wherein, Each of the two ends of the left and right spiral screws (211) is screwed with an outer sleeve (212). The end of the outer sleeve (212) away from the left and right spiral screws (211) is fixedly connected with the supporting leg (3). The side of the outer sleeve (212) is fixedly connected with the side end of the elastic tray (1).
4. A novel cell culture bag holder according to claim 3, characterized in that: The middle part of the left and right spiral screws (211) is provided with a knob part (21101).
5. A novel cell culture bag holder according to claim 2, characterized in that: The elastic tray (1) is an elastic rubber plate, and a plurality of air holes (101) are vertically arranged on the elastic tray (1).
6. A novel cell culture bag holder according to claim 2, characterized in that: The elastic tray (1) is an elastic net.
7. A novel cell culture bag holder according to claim 5 or 6, characterized in that: It also comprises elastic ropes (4), wherein, A plurality of elastic ropes (4) are arranged above the elastic tray (1) for fixing the culture bags placed in the culture bag placing groove (201). The two ends of the elastic rope (4) are detachably arranged on the frame (2).
8. A novel cell culture bag holder according to claim 7, characterized in that: The two ends of the elastic rope (4) are provided with hook parts (401), wherein, The hook parts (401) are hung on the side of the telescopic rod (21).
9. A novel cell culture bag holder according to claim 8, characterized in that: A plurality of elastic ropes (4) are arranged in parallel or intersected.
10. A novel cell culture bag holder according to claim 1, characterized in that: The upper end of the supporting leg (3) is provided with a plug part (301), and the lower end is provided with a slot part (302), wherein the inner diameter of the plug part (301) is greater than or equal to the outer diameter of the slot part (302).
Citation Information
Patent Citations
Folded cascade bracing piece
CN206947495U
Cultivate supporting cultivation tray that uses of bag with immune cell
CN208308876U