Precise centrifugal separator for purifying levoparoxol

Abstract

The precise centrifugal separator comprises a mixing box, the lower end of the mixing box is fixedly connected with a collecting hopper, the lower end of the collecting hopper is fixedly connected with a separating box, the upper end of the mixing box is provided with a driving motor, the output end of the driving motor is fixedly connected with a rotating rod, and the rotating rod is fixedly connected with a rotating shaft. The precise centrifugal separator comprises a mixing box and a rotating rod, the rotating rod is rotatably connected with the mixing box, the outer side of the rotating rod is fixedly connected with a spiral blade, and the spiral blade is arranged in an inner cavity of the mixing box. According to the levoparoxol separation device, the filter screen is arranged, so that a levoparoxol mixture attached to the upper end of the filter screen can be stirred, the problem that the filter effect is reduced due to the fact that filter holes of the filter screen are blocked by particle impurities can be effectively prevented, and the filtered levoparoxol mixture falls into a separation box through a collection hopper to realize separation of levoparoxol.

Description

Technical Field

[0001] This utility model relates to the field of L-paroxetine purification, and in particular to a precision centrifuge for L-paroxetine purification. Background Technology

[0002] Levoparol is mainly used to treat mental and neurological disorders. It has a good therapeutic effect on mental disorders such as depression and anxiety. By increasing the availability of 5-HT, it affects the neural pathways in the brain related to mood regulation, thereby alleviating patients' depressive symptoms, such as low mood, loss of interest, and sleep disorders, as well as anxiety symptoms, including excessive worry and tension.

[0003] In the production and preparation of levamisole, the mixture often contains various impurities. The presence of large particles can seriously affect the purity of the product and the subsequent processes. Existing centrifuges have problems such as incomplete separation of large particles, easy clogging of equipment, and poor control of material flow when processing such mixtures. Secondly, traditional stirring components usually stir the levamisole mixture in a single direction, which cannot allow the material to rise and mix thoroughly. This makes it impossible to break up any agglomerates between the materials and to ensure that the material flows evenly into the centrifuge chamber, resulting in poor separation of different components during centrifugation. To solve the above problems, we propose a precision centrifuge for levamisole purification. Utility Model Content

[0004] The main purpose of this invention is to provide a precision centrifuge for the purification of L-paroxetine, which can effectively solve the problems in the background art.

[0005] To achieve the above objectives, the technical solution adopted by this utility model is as follows:

[0006] A precision centrifuge for purifying levamisole includes a mixing chamber, a collection hopper fixedly connected to the lower end of the mixing chamber, a separation chamber fixedly connected to the lower end of the collection hopper, a drive motor mounted on the upper end of the mixing chamber, a rotating rod fixedly connected to the output end of the drive motor, the rotating rod being rotatably connected to the mixing chamber, a helical blade fixedly connected to the outer side of the rotating rod, the helical blade being disposed within the inner cavity of the mixing chamber, a first transmission assembly and a second transmission assembly also being disposed on the outer side of the rotating rod, both the first and second transmission assemblies being disposed at the upper end of the mixing chamber, and a stirring assembly being disposed at the other end of both the first and second transmission assemblies, both of which are disposed within the inner cavity of the mixing chamber.

[0007] Preferably, a fixing rod is fixedly connected to the inner wall of the mixing box, the spiral blade is rotatably connected to the fixing rod, a rotating brush is fixedly connected to the lower end of the spiral blade, a filter screen is movably connected to the lower end of the rotating brush, and the filter screen is fixedly connected at the intersection of the collecting hopper and the separating box.

[0008] Preferably, the stirring assembly includes an upper rotating rod, which is rotatably connected to the mixing chamber. An upper conical wheel is fixedly connected to the lower end of the upper rotating rod. A transmission conical wheel meshes with the outer side of the upper conical wheel. One side of the transmission conical wheel is rotatably connected to the inner wall of the mixing chamber. A lower conical wheel meshes with the outer side of the transmission conical wheel. The upper conical wheel is connected to the lower conical wheel via the transmission conical wheel.

[0009] Preferably, a lower rotating rod is fixedly connected to the lower end of the lower conical wheel, and the lower rotating rod is rotatably connected to the upper end of the fixed rod. Multiple stirring rods are fixedly connected to the outer sides of both the lower rotating rod and the upper rotating rod.

[0010] Preferably, the first transmission assembly includes a first driving wheel, which is fixedly connected to the outside of the rotating rod. A first belt is sleeved on the outside of the first driving wheel, and a first driven wheel is fixedly connected to the upper end of the upper rotating rod near the front end. The first driving wheel is connected to the first driven wheel through the first belt.

[0011] Preferably, the second transmission assembly includes a second drive wheel, a second belt is sleeved on the outer side of the second drive wheel, and the second drive wheel is located at the lower end of the first drive wheel. A second driven wheel is fixedly connected to the upper end of the upper rotating rod near the rear end. The second drive wheel is fixedly connected to the second driven wheel through the second belt.

[0012] Preferably, a mounting block is fixedly connected to the outside of the drive motor, and the drive motor is fixedly mounted on the upper end of the mixing tank by the mounting block.

[0013] Preferably, the mixing chamber is provided with a feed door at the upper end and a cleaning door is provided on the outer side of the mixing chamber, with the bottom end of the cleaning door being higher than the top end of the filter screen.

[0014] Compared with the prior art, the present invention has the following beneficial effects:

[0015] 1. This precision centrifuge for purifying L-paroyl alcohol uses a drive motor to rotate a rotating rod. This rotation drives the spiral blades, which in turn stir the L-paroyl alcohol mixture in the mixing chamber. Through the cooperation of the first and second transmission components, the rotating rod drives two upper rotating rods to rotate. The upper conical wheel, transmission conical wheel, and lower conical wheel facilitate the reverse rotation of the lower rotating rod above the fixed rod. This further stirs the L-paroyl alcohol mixture in the mixing chamber, effectively breaking up any agglomeration and ensuring a more uniform flow of material into the separation chamber. This improves the separation efficiency of different components during centrifugation, thereby enhancing the purification quality of L-paroyl alcohol.

[0016] 2. This precision centrifuge for purifying L-paroxetine uses a rotating rod that also drives a rotating brush to rotate on the upper part of the filter screen. This agitates the L-paroxetine mixture adhering to the upper part of the filter screen, effectively preventing the filter screen from being clogged by particulate impurities and reducing the filtration efficiency. The filtered L-paroxetine mixture will fall into the separation box through the collection hopper to achieve the separation of L-paroxetine. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the overall structure of the precision centrifuge for the purification of L-paroxetine according to this utility model. Figure 1 ;

[0018] Figure 2 This is a schematic diagram of the overall structure of the precision centrifuge for the purification of L-paroxetine according to this utility model. Figure 2 ;

[0019] Figure 3 This is a cross-sectional view of the overall structure of the precision centrifuge for the purification of L-paroxetine according to this utility model;

[0020] Figure 4 This is a partial structural schematic diagram of the precision centrifuge for the purification of L-paroxetine according to this utility model;

[0021] Figure 5 This is an enlarged structural diagram of point A of the precision centrifuge for the purification of levoparool according to this utility model.

[0022] In the diagram: 1. Mixing box; 2. Collecting hopper; 3. Separating box; 4. Drive motor; 5. Mounting block; 6. First transmission assembly; 61. First driving wheel; 62. First belt; 63. First driven wheel; 7. Second transmission assembly; 71. Second driving wheel; 72. Second belt; 73. Second driven wheel; 8. Rotating rod; 9. Spiral blade; 10. Fixed rod; 11. Upper rotating rod; 12. Upper conical wheel; 13. Transmission conical wheel; 14. Lower conical wheel; 15. Lower rotating rod; 16. Stirring rod; 17. Rotating brush; 18. Filter screen; 19. Feed gate; 20. Cleaning gate. Detailed Implementation

[0023] To make the technical means, creative features, objectives and effects of this utility model easier to understand, the present utility model will be further described below in conjunction with specific embodiments.

[0024] like Figure 1-5 As shown, a precision centrifuge for purifying levoparool includes a mixing chamber 1. A collection hopper 2 is fixedly connected to the lower end of the mixing chamber 1, and a separation chamber 3 is fixedly connected to the lower end of the collection hopper 2. A drive motor 4 is installed at the upper end of the mixing chamber 1. A rotating rod 8 is fixedly connected to the output end of the drive motor 4. The rotating rod 8 is rotatably connected to the mixing chamber 1. A spiral blade 9 is fixedly connected to the outer side of the rotating rod 8. The spiral blade 9 is located in the inner cavity of the mixing chamber 1. A first transmission assembly 6 and a second transmission assembly 7 are also installed on the outer side of the rotating rod 8. Both the first transmission assembly 6 and the second transmission assembly 7 are located at the upper end of the mixing chamber 1. A stirring assembly is installed at the other end of both the first transmission assembly 6 and the second transmission assembly 7. Both stirring assemblies are located in the inner cavity of the mixing chamber 1.

[0025] In this embodiment, a fixed rod 10 is fixedly connected to the inner wall of the mixing box 1, the spiral blade 9 is rotatably connected to the fixed rod 10, a rotating brush 17 is fixedly connected to the lower end of the spiral blade 9, a filter screen 18 is movably connected to the lower end of the rotating brush 17, and the filter screen 18 is fixedly connected at the intersection of the collecting hopper 2 and the separating box 3.

[0026] Specifically, by starting the drive motor 4, the output end of the drive motor 4 will drive the rotating rod 8 to rotate. The rotation of the rotating rod 8 will drive the spiral blade 9 to rotate. The rotation of the spiral blade 9 can initially stir the L-parool mixture in the mixing box 1. At this time, the rotation of the rotating rod 8 will also drive the rotating brush 17 to rotate on the upper end of the filter screen 18, which can then move the L-parool mixture attached to the upper end of the filter screen 18. This can effectively prevent the filter screen 18 from being blocked by particulate impurities and thus reduce the filtration effect. The filtered L-parool mixture will fall into the separation box 3 through the collection hopper 2 to achieve the separation of L-parool.

[0027] In this embodiment, the stirring assembly includes an upper rotating rod 11, which is rotatably connected to the mixing tank 1. An upper conical wheel 12 is fixedly connected to the lower end of the upper rotating rod 11. A transmission conical wheel 13 meshes with the outer side of the upper conical wheel 12. One side of the transmission conical wheel 13 is rotatably connected to the inner wall of the mixing tank 1. A lower conical wheel 14 meshes with the outer side of the transmission conical wheel 13. The upper conical wheel 12 is connected to the lower conical wheel 14 via the transmission conical wheel 13. A lower rotating rod 15 is fixedly connected to the lower end of the lower conical wheel 14. The lower rotating rod 15 is rotatably connected to the upper end of the fixed rod 10. Multiple stirring rods 16 are fixedly connected to the outer sides of both the lower rotating rod 15 and the upper rotating rod 11.

[0028] Specifically, the rotation of the upper rotating rod 11 will drive the upper conical wheel 12 to rotate. At this time, through the transmission cooperation of the transmission conical wheel 13 and the lower conical wheel 14, the lower rotating rod 15 can be easily rotated in the opposite direction at the upper end of the fixed rod 10. The rotation of the upper rotating rod 11 and the lower rotating rod 15 can cause multiple stirring rods 16 to further stir the L-parool mixture in the inner cavity of the mixing box 1, which can effectively break the possible agglomeration between materials, make the materials flow more evenly into the separation box 3, improve the separation effect of different components during centrifugation, and thus improve the purification quality of L-parool.

[0029] In this embodiment, the first transmission assembly 6 includes a first driving wheel 61, which is fixedly connected to the outside of the rotating rod 8. A first belt 62 is sleeved on the outside of the first driving wheel 61. A first driven wheel 63 is fixedly connected to the upper end of the upper rotating rod 11 near the front end. The first driving wheel 61 is connected to the first driven wheel 63 through the first belt 62. The second transmission assembly 7 includes a second driving wheel 71, which is sleeved on the outside of the second driving wheel 71 and is located at the lower end of the first driving wheel 61. A second driven wheel 73 is fixedly connected to the upper end of the upper rotating rod 11 near the rear end. The second driving wheel 71 is fixedly connected to the second driven wheel 73 through the second belt 72.

[0030] Specifically, as the rotating rod 8 rotates, it also drives the first driving wheel 61 to rotate. At this time, with the cooperation of the first belt 62, the first driven wheel 63 can easily drive the upper rotating rod 11 near the front end to rotate. Similarly, the rotation of the rotating rod 8 will also drive the second driving wheel 71 to rotate. With the transmission cooperation of the second belt 72, the second driven wheel 73 can easily drive the upper rotating rod 11 near the rear end to rotate.

[0031] In this embodiment, a mounting block 5 is fixedly connected to the outside of the drive motor 4, and the drive motor 4 is fixedly mounted on the upper end of the mixing box 1 through the mounting block 5.

[0032] Specifically, the design of mounting block 5 can effectively improve the stability of drive motor 4 during operation.

[0033] In this embodiment, a feed door 19 is provided at the upper end of the mixing box 1, and a cleaning door 20 is provided on the outer side of the mixing box 1. The bottom end of the cleaning door 20 is higher than the top end of the filter screen 18.

[0034] Specifically, the design of the feed door 19 allows users to easily add the mixture containing L-parool into the inner cavity of the mixing chamber 1. The design of the cleaning door 20 allows for easy opening of the cleaning door 20, thereby cleaning the particulate impurities filtered out from the upper end of the filter screen 18.

[0035] It should be noted that this utility model is a precision centrifugal separator for the purification of L-paroxetine. The user can add the mixture containing L-paroxetine into the inner cavity of the mixing chamber 1 through the feed gate 19. At this time, the drive motor 4 is started, and the output end of the drive motor 4 drives the rotating rod 8 to rotate. The rotation of the rotating rod 8 drives the spiral blades 9 to rotate, which in turn allows for preliminary stirring of the L-paroxetine mixture in the mixing chamber 1. Simultaneously, the rotation of the rotating rod 8 also drives the rotating brush 17 to rotate above the filter screen 18, thereby agitating the L-paroxetine mixture adhering to the upper part of the filter screen 18. This effectively prevents the filter screen 18 from being clogged by particulate impurities, thus reducing the filtration effect. The filtered L-paroxetine mixture falls into the separation chamber 3 through the collection hopper 2, achieving the separation of L-paroxetine. Simultaneously, the rotation of the rotating rod 8 also drives the first driving wheel 61 to rotate. With the cooperation of the first belt 62, the first driven wheel 63 can easily drive the upper part near the front end... Rotating rod 11 rotates, and similarly, rotating rod 8 also drives the second driving wheel 71 to rotate. Through the transmission of the second belt 72, the second driven wheel 73 can easily drive the upper rotating rod 11 near the rear end to rotate. At this time, the rotation of the upper rotating rod 11 will drive the upper conical wheel 12 to rotate. Then, through the transmission of the transmission conical wheel 13 and the lower conical wheel 14, the lower rotating rod 15 can easily rotate in the opposite direction at the upper end of the fixed rod 10. Through the rotation of the upper rotating rod 11 and the lower rotating rod 15, multiple stirring rods 16 can further stir the L-parool mixture in the mixing chamber 1, which can effectively break the possible agglomeration between materials, so that the materials flow more evenly into the separation chamber 3, improve the separation effect of different components during centrifugation, and thus improve the purification quality of L-parool. After all the L-parool mixture has been filtered, the cleaning door 20 can be opened to easily clean the particulate impurities filtered out at the upper end of the filter screen 18, which is quite practical.

[0036] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claims. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. A precision centrifuge for purifying levamisole, comprising a mixing chamber (1), characterized in that: The lower end of the mixing box (1) is fixedly connected to a hopper (2), and the lower end of the hopper (2) is fixedly connected to a separator (3). The upper end of the mixing box (1) is provided with a drive motor (4), and the output end of the drive motor (4) is fixedly connected to a rotating rod (8). The rotating rod (8) is rotatably connected to the mixing box (1). The outer side of the rotating rod (8) is fixedly connected to a spiral blade (9). The spiral blade (9) is located in the inner cavity of the mixing box (1). The outer side of the rotating rod (8) is also provided with a first transmission assembly (6) and a second transmission assembly (7). The first transmission assembly (6) and the second transmission assembly (7) are both located at the upper end of the mixing box (1). The other end of the first transmission assembly (6) and the second transmission assembly (7) are both provided with a stirring assembly. Both stirring assemblies are located in the inner cavity of the mixing box (1).

2. The precision centrifuge for purifying L-paroxetine according to claim 1, characterized in that: The inner wall of the mixing box (1) is fixedly connected to a fixed rod (10), the spiral blade (9) is rotatably connected to the fixed rod (10), the lower end of the spiral blade (9) is fixedly connected to a rotating brush (17), the lower end of the rotating brush (17) is movably connected to a filter screen (18), and the filter screen (18) is fixedly connected at the intersection of the collecting hopper (2) and the separating box (3).

3. The precision centrifuge for purifying L-paroxetine according to claim 1, characterized in that: The stirring assembly includes an upper rotating rod (11), which is rotatably connected to the mixing tank (1). An upper conical wheel (12) is fixedly connected to the lower end of the upper rotating rod (11). A transmission conical wheel (13) meshes with the outer side of the upper conical wheel (12). One side of the transmission conical wheel (13) is rotatably connected to the inner wall of the mixing tank (1). A lower conical wheel (14) meshes with the outer side of the transmission conical wheel (13). The upper conical wheel (12) is connected to the lower conical wheel (14) through the transmission conical wheel (13).

4. The precision centrifuge for purifying L-paroxetine according to claim 3, characterized in that: The lower end of the lower conical wheel (14) is fixedly connected to a lower rotating rod (15), which is rotatably connected to the upper end of the fixed rod (10). Multiple stirring rods (16) are fixedly connected to the outer sides of both the lower rotating rod (15) and the upper rotating rod (11).

5. The precision centrifuge for purifying L-paroxetine according to claim 4, characterized in that: The first transmission assembly (6) includes a first drive wheel (61), which is fixedly connected to the outside of the rotating rod (8). A first belt (62) is sleeved on the outside of the first drive wheel (61). A first driven wheel (63) is fixedly connected to the upper end of the upper rotating rod (11) near the front end. The first drive wheel (61) is connected to the first driven wheel (63) through the first belt (62).

6. The precision centrifuge for purifying L-paroxetine according to claim 5, characterized in that: The second transmission assembly (7) includes a second drive wheel (71), a second belt (72) is sleeved on the outer side of the second drive wheel (71), and the second drive wheel (71) is located at the lower end of the first drive wheel (61). The upper end of the upper rotating rod (11) near the rear end is fixedly connected to a second driven wheel (73). The second drive wheel (71) is fixedly connected to the second driven wheel (73) through the second belt (72).

7. The precision centrifuge for purifying L-paroxetine according to claim 1, characterized in that: The drive motor (4) is fixedly connected to the outside of the mounting block (5), and the drive motor (4) is fixedly mounted on the upper end of the mixing box (1) by the mounting block (5).

8. The precision centrifuge for purifying L-paroxetine according to claim 1, characterized in that: The mixing box (1) is provided with a feed door (19) at the upper end and a cleaning door (20) is provided on the outer side of the mixing box (1). The bottom end of the cleaning door (20) is higher than the top end of the filter screen (18).

Images