Ion chromatograph
By designing various sample determination tube assemblies and an automated sample introduction system, the applicability of existing ion chromatographs in determining hydrogen peroxide and trace ions has been solved, achieving a wider range of sample determination capabilities and more accurate detection.
Patent Information
- Application Number
- CN202423119740.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-17
- Publication Date
- 2025-12-09
- Estimated Expiration
- 2034-12-17
AI Technical Summary
Existing ion chromatographs are prone to frequent malfunctions when measuring hydrogen peroxide samples and cannot effectively detect trace ion content, thus limiting their applicability.
An ion chromatograph was designed, comprising a six-way valve, a chromatographic analysis device, and an inlet/outlet mechanism. It employs first and second sample determination tube assemblies for routine and trace sample determination, respectively. Combined with an ultrafiltration assembly, a purification column, an autosampler, and an eluent supply device, it achieves automated and accurate detection.
This improves the applicability of ion chromatographs, enabling the effective determination of various samples, especially hydrogen peroxide and trace ions, reducing manual operation and improving detection accuracy and efficiency.
Smart Images
Figure CN223650517U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to ion chromatography analysis technical field especially, is ion chromatograph. BACKGROUND
[0002] Ion chromatography is the most common analysis method in modern chemical analysis technology, which has the advantages of high efficiency and accuracy. The existing ion chromatography in the laboratory is a general ion chromatography on the market, which is applicable to the determination of general samples, but it may cause various problems in the determination of some special samples, limiting its application range. For example, when determining the new hydrogen peroxide sample of the company, the strong oxidizing property of hydrogen peroxide may cause frequent instrument failure. For example, the ion content such as nitrate in hydrogen peroxide is close to trace, and the existing equipment cannot detect it.
[0003] Therefore, it is particularly important to provide an ion chromatograph capable of enhancing the determination range to meet the determination of samples in different situations. UTILITY MODEL CONTENT
[0004] The utility model aims at providing an ion chromatograph to solve the problems in the prior art, which can determine samples in various situations and improve the application range.
[0005] To achieve the above object, the utility model provides the following scheme:
[0006] The utility model provides a kind of ion chromatograph, including six-way valve, chromatographic analysis device and liquid inlet and outlet mechanism;The six-way valve has the first connecting port, second connecting port, third connecting port, fourth connecting port, fifth connecting port and sixth connecting port that can be interconnected;The chromatographic analysis device has eluent outlet and detection inlet;The eluent outlet is communicated with the fifth connecting port of the six-way valve, and the detection inlet is communicated with the sixth connecting port of the six-way valve;The liquid inlet and outlet mechanism includes sample needle, first sample determination tube component and second sample determination tube component;For first sample determination, the liquid inlet and outlet mechanism includes the sample needle and first sample determination tube component;The first sample determination tube component includes first sample tube, first quantitative ring and first liquid discharge tube;The inlet end of the sample needle is used to communicate with sample bottle containing sample, and the outlet end of the sample needle is communicated with the inlet end of the first sample tube;The outlet end of the first sample tube is used to communicate with the first connecting port of the six-way valve, and sample peristaltic pump is connected on the first sample tube;One end of the first quantitative ring is communicated with the third connecting port of the six-way valve, and the other end of the first quantitative ring is communicated with the fourth connecting port of the six-way valve;The inlet end of the first liquid discharge tube is communicated with the second connecting port of the six-way valve;For second sample determination, the liquid inlet and outlet mechanism includes the sample needle and the second sample determination tube component;The second sample determination tube component includes enrichment column, washing bottle, suction pump, first branch pipe, second branch pipe, second quantitative ring, buffer tube, three-way valve, second sample tube and second liquid discharge tube;One end of the enrichment column is communicated with the third connecting port of the six-way valve, and the other end of the enrichment column is communicated with the fourth connecting port of the six-way valve;The washing bottle is used to store ultrapure water;One end communication port of the suction pump is communicated with the inside of the washing bottle, and the other end communication port of the suction pump is respectively connected with the first branch pipe and the second branch pipe, and single connection port of the suction pump can form suction port and discharge port;The three-way valve has first communication port, second communication port and third communication port;The other end of the first branch pipe is communicated with the second communication port, and the other end of the second branch pipe is communicated with the third communication port, and the second quantitative ring and the buffer tube are sequentially connected on the second branch pipe, the second quantitative ring is located on the side close to the three-way valve, and the capacity of the second quantitative ring is greater than the capacity of the first quantitative ring;One end of the second sample tube is communicated with the first communication port of the three-way valve, and the other end of the second sample tube is used to communicate with the second connecting port of the six-way valve;One end of the second liquid discharge tube is used to communicate with the first connecting port of the six-way valve, and the other end of the second liquid discharge tube is used to communicate with one end of the sample needle, and the other end of the sample needle is used to communicate with waste liquid cup.
[0007] Preferably, the second sample assay tube assembly further comprises a purification column, which is connected to the first branch tube.
[0008] Preferably, the first sample assay tube assembly further comprises an ultrafiltration assembly, which is arranged on the first sample inlet tube; the ultrafiltration assembly is located between the sample inlet peristaltic pump and the first connecting port of the six-way valve.
[0009] Preferably, the liquid inlet and outlet mechanism further comprises an automatic sample injector, which has a rotating turntable; for the first sample assay, a plurality of sample bottles are arranged on the turntable; for the second sample assay, the waste liquid cup is arranged on the turntable.
[0010] Preferably, the second sample assay tube assembly further comprises a controller, which is in communication connection with the three-way valve and the suction and discharge pump.
[0011] Preferably, the chromatographic analysis device comprises an eluent supply device and a chromatographic separation and detection device; the eluent supply device comprises an eluent bottle and an eluent supply pump; the eluent bottle is used for containing eluent; the inlet end of the eluent supply pump is located in the eluent bottle, and the outlet end of the eluent supply pump is used for being in communication with the fifth connecting port of the six-way valve; the chromatographic separation and detection device comprises a chromatographic separation column and a detector which are connected and communicated in sequence; the inlet end of the chromatographic separation column is in communication with the sixth connecting port of the six-way valve.
[0012] Preferably, the first quantitative ring is a 20uL quantitative ring, and the second quantitative ring is a 1mL quantitative ring.
[0013] Preferably, the connections between the first sample assay tube assembly, the six-way valve and the sample inlet needle and the connections between the second sample assay tube assembly, the six-way valve and the sample inlet needle all adopt union joints.
[0014] Preferably, the materials of all positions in contact with the assay sample are materials that do not affect the assay results according to the characteristics of the assay sample.
[0015] Preferably, the chromatographic separation and detection device further comprises an inhibitor, which is arranged between the chromatographic separation column and the detector.
[0016] The utility model discloses the following technical effects are obtained relative to the prior art:
[0017] The ion chromatograph provided by the utility model discloses, through adopting two structures of the first sample determination tube assembly and the second sample determination tube assembly, the determination needs of different samples are adapted: when the sample is a conventional sample determination, the related components of the first sample determination tube assembly can be installed, and the sample is taken to the detection entrance for detection determination under the driving of the mobile phase (eluent); when the content of the sample to be determined is low, such as close to trace, the related components of the second sample determination tube assembly can be installed, the sample is stored in the buffer tube through the cooperation of the second quantitative ring and the buffer tube by the sample pump, the sample in the buffer tube is discharged to the enrichment column for enrichment by the sample pump, and then the sample is taken to the detection entrance by the mobile phase (eluent) to complete detection determination, so that the problem of low ion content and difficult quantification in the sample is solved by increasing the sample amount; and the sample pump can cooperate with the three-way valve and ultrapure water to realize the flushing of the pipeline, and the waste liquid after flushing is discharged into the waste liquid cup, so that the matrix in the sample to be determined which has interference on sample detection and strong oxidizing property (corrosion) on the pipeline of the instrument is effectively eliminated; the whole can realize the determination of samples in various conditions by replacing different determination tube assemblies, and the application range is improved.
[0018] Further, the purification column can purify ultrapure water, ensure accurate detection results, and reduce interference in the case of analyzing trace substances or requiring extremely high analysis accuracy.
[0019] Further, the ultrafiltration assembly can effectively trap impurities in the sample, improve sample purity, reduce interference, and ensure the accuracy of the detection results.
[0020] Further, in the first sample determination, multiple sample bottles are placed on the turntable of the automatic sample injector, which can realize automatic continuous sampling, which means that the instrument can sequentially suck samples from different sample bottles for analysis according to the preset program without manual sample replacement; in the second sample determination, the waste liquid cup is arranged on the turntable, which facilitates the collection of waste liquid. In the complex sample pretreatment process, such as the washing of the enrichment column and the flushing of the sample needle, a large amount of waste liquid will be generated. By placing the waste liquid cup on the turntable of the automatic sample injector, the waste liquid can be directly discharged into the waste liquid cup through the sample needle and other components, and centralized collection is realized.
[0021] Further, the controller is in communication connection with the three-way valve, which can accurately control the opening and closing states of each communication port of the three-way valve, and cooperate with the control of the sample pump. With the help of the controller, multiple steps in the second sample determination process can be automated, which not only reduces the complexity and workload of manual operation, but also avoids errors caused by human factors.
[0022] Further, the elution supply pump in the elution supply device can accurately control the supply of the elution liquid, and the flow of the elution liquid can be flexibly adjusted according to different sample types and analysis requirements through the elution supply pump; the elution supply device and the chromatographic separation and detection device closely cooperate in the chromatographic analysis process, the elution liquid carries the sample into the chromatographic separation column, and the separated ions are detected by the detector, and the whole process is a coherent system. The cooperative working mode can guarantee the efficiency and accuracy of the analysis process.
[0023] Further, the 20 muL quantification ring is suitable for measuring a sample with a conventional concentration, and the volume is relatively small, and is very suitable for a sample with a high ion concentration or a sample that only needs a small amount of injection to meet the detection requirement; the 1 mL quantification ring has a large capacity, and is mainly used for enriching a low-concentration sample, and when trace ions such as heavy metal ions in an environmental water sample or trace ion components in a biological sample need to be detected, a large injection amount can ensure that enough target ions are introduced into the chromatographic analysis device; for a complex sample that may contain a plurality of ion components, the 1 mL quantification ring can contain as many ion components as possible in one injection, so that the sample can be comprehensively analyzed in the chromatographic separation and detection process.
[0024] Further, in the assembly process of the ion chromatograph, the use of the live joint can make the connection between the first sample measuring tube assembly, the second sample measuring tube assembly, the six-way valve and the injection needle more convenient, and the technician can easily complete the assembly and switching of the components without complex tools or professional connection skills.
[0025] Further, by selecting a suitable material according to different sample characteristics, the ion chromatograph can be compatible with more types of samples, and the accuracy of the detection and measurement results can be ensured.
[0026] Further, the suppressor can eliminate CO2, reduce detection interference factors, and improve measurement accuracy. BRIEF DESCRIPTION OF DRAWINGS
[0027] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the drawings needed in the embodiments will be briefly introduced as follows. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can also be obtained by those skilled in the art without creative labor on the basis of these drawings.
[0028] Figure 1 The overall structure schematic diagram of the ion chromatograph provided by the present application is shown in the figure.
[0029] In the figure:
[0030] 10-rotating disc; 11-injection needle;
[0031] 20 - first sample inlet tube; 21 - sample inlet peristaltic pump; 22 - ultrafiltration assembly; 23 - first dosing ring; 24 - first drain tube;
[0032] 30 - second sample inlet tube; 31 - enrichment column; 32 - washing bottle; 33 - suction pump; 34 - first branch tube; 341 - purification column; 35 - second branch tube; 351 - buffer tube; 352 - second dosing ring; 36 - three-way valve; 37 - second drain tube; 38 - waste cup; 39 - controller;
[0033] 40 - six-way valve;
[0034] 50 - eluent bottle; 51 - eluent supply pump;
[0035] 60 - chromatographic separation column; 61 - suppressor; 62 - detector. DETAILED DESCRIPTION
[0036] The technical solutions in the embodiments of the present application will be described clearly and completely below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative work fall within the scope of protection of the present application.
[0037] The present application provides an ion chromatograph, so as to solve the problems in the prior art, and can determine samples in various situations, thereby improving the application range.
[0038] In order to make the above-mentioned purposes, features and advantages of the present application more apparent, obvious and easy to understand, the present application will be further described in detail below with reference to the drawings and specific embodiments.
[0039] Embodiment one
[0040] The present embodiment provides an ion chromatograph, such as Figure 1As shown, it comprises a six-way valve 40, a chromatographic analysis device and a liquid inlet and outlet mechanism; the six-way valve 40 has a first connecting port, a second connecting port, a third connecting port, a fourth connecting port, a fifth connecting port and a sixth connecting port which can communicate with each other; the chromatographic analysis device has a washing liquid outlet and a detection inlet; the washing liquid outlet communicates with the fifth connecting port of the six-way valve 40, and the detection inlet communicates with the sixth connecting port of the six-way valve 40; the liquid inlet and outlet mechanism comprises a sample injection needle 11, a first sample measuring tube assembly and a second sample measuring tube assembly; for the first sample measurement, the liquid inlet and outlet mechanism comprises the sample injection needle 11 and the first sample measuring tube assembly; the first sample measuring tube assembly comprises a first sample injection tube 20, a first quantitative ring 23 and a first liquid outlet tube 24; the inlet end of the sample injection needle 11 is used to communicate with a sample bottle containing a sample, and the outlet end of the sample injection needle 11 communicates with the inlet end of the first sample injection tube 20; the outlet end of the first sample injection tube 20 is used to communicate with the first connecting port of the six-way valve 40, and a sample injection peristaltic pump 21 is connected to the first sample injection tube 20; one end of the first quantitative ring 23 communicates with the third connecting port of the six-way valve 40, and the other end of the first quantitative ring 23 communicates with the fourth connecting port of the six-way valve 40; the inlet end of the first liquid outlet tube 24 communicates with the second connecting port of the six-way valve 40; for the second sample measurement, the liquid inlet and outlet mechanism comprises the sample injection needle 11 and the second sample measuring tube assembly; the second sample measuring tube assembly comprises an enrichment column 31, a washing bottle 32, a suction pump 33, a first branch tube 34, a second branch tube 35, a second quantitative ring 352, a buffer tube 351, a three-way valve 36, a second sample injection tube 30 and a second liquid outlet tube 37; one end of the enrichment column 31 communicates with the third connecting port of the six-way valve 40, and the other end of the enrichment column 31 communicates with the fourth connecting port of the six-way valve 40; the washing bottle 32 is used to store ultrapure water; one end of the suction pump 33 communicates with the inside of the washing bottle 32, and the other end of the suction pump 33 is connected with the first branch tube 34 and the second branch tube 35 respectively, and a single connecting port of the suction pump 33 can form a suction port or a discharge port (i.e. the suction pump 33 can extract ultrapure water, and can also extract the sample and push the sample in the buffer tube 351 out to the enrichment column 31); the three-way valve 36 has a first connecting port, a second connecting port and a third connecting port; the other end of the first branch tube 34 communicates with the second connecting port, the other end of the second branch tube 35 communicates with the third connecting port, the second quantitative ring 352 and the buffer tube 351 are connected in sequence on the second branch tube 35, the second quantitative ring 352 is located on the side close to the three-way valve 36, and the capacity of the second quantitative ring 352 is greater than that of the first quantitative ring 23; one end of the second sample injection tube 30 communicates with the first connecting port of the three-way valve 36, and the other end of the second sample injection tube 30 is used to communicate with the second connecting port of the six-way valve 40; one end of the second liquid outlet tube 37 is used to communicate with the first connecting port of the six-way valve 40, and the other end of the second liquid outlet tube 37 is used to communicate with one end of the sample injection needle 11, and the other end of the sample injection needle 11 is used to communicate with a waste liquid cup 38.
[0041] By adopting two structures of the first sample determination tube assembly and the second sample determination tube assembly, the determination needs of different samples are met: when the sample is a conventional sample, the relevant components of the first sample determination tube assembly are installed, and the sample is carried to the detection inlet by the mobile phase (eluent) for detection determination; when the content of the sample to be determined is low, such as close to trace, the relevant components of the second sample determination tube assembly are installed, the sample is stored in the buffer tube 351 through the multiple quantitative sample storage in the buffer tube 351 by the pumping pump 33 cooperating with the second quantitative ring 352 and the buffer tube 351, and the sample in the buffer tube 351 is pumped to the enrichment column 31 by the pumping pump 33 for enrichment, and then is carried to the detection inlet by the mobile phase (eluent) to complete the detection determination, so as to increase the sample amount to solve the problem of low ion content in the sample and difficult quantification; and the pumping pump 33 can cooperate with the three-way valve 36 and ultrapure water to realize the flushing of the pipeline, and the flushing waste liquid is discharged into the waste liquid cup 38, so as to effectively eliminate the matrix in the sample to be determined which interferes with the sample detection and has strong oxidizing property (corrosivity) to the instrument pipeline; the whole can realize the determination of samples in various conditions by replacing different determination tube assemblies, and the application range is improved.
[0042] In addition, the second sample determination tube assembly also includes a first branch pipe 34, a second branch pipe 35, a pumping pump 33, a three-way valve 36, an enrichment column 31, a buffer tube 351, and a waste liquid cup 38.
[0043] In the optional solution of the embodiment, preferably, as shown in Figure 1 The first sample determination tube assembly further includes an ultrafiltration assembly 22, which is arranged on the first sample inlet pipe 20; the ultrafiltration assembly 22 is located between the sample inlet peristaltic pump 21 and the first connecting port of the six-way valve 40. The ultrafiltration assembly 22 can effectively trap impurities in the sample, improve the purity of the sample, reduce interference, and ensure the accuracy of the detection result.
[0044] In addition, the second sample determination tube assembly also includes a first branch pipe 34, a second branch pipe 35, a pumping pump 33, a three-way valve 36, an enrichment column 31, a buffer tube 351, and a waste liquid cup 38.
[0045] Specifically, the enrichment column 31 is used for enriching the component to be determined, and the interfering matrix is washed away by ultrapure water.
[0046] In the optional solution of the embodiment, preferably, as shown in Figure 1 The second sample determination tube assembly further includes a purification column 341, which is connected to the first branch pipe 34. The purification column 341 can purify the ultrapure water, and in the case of analyzing trace substances or requiring extremely high analysis accuracy, the accurate detection result is ensured, and the interference is reduced.
[0047] Specifically, the purification column 341 is used for further purifying the water used in the experiment, and capturing the ions affecting the component to be determined.
[0048] In the optional solution of the embodiment, preferably, as shown in Figure 1As shown, the second sample determination tube assembly further comprises a controller 39, which is in communication connection with the three-way valve 36 and the suction and discharge pump 33. Through the communication connection between the controller 39 and the three-way valve 36, the opening and closing states of each communication port of the three-way valve 36 can be accurately controlled, and the suction and discharge pump 33 is controlled in cooperation, so that multiple steps in the second sample determination process can be automated by means of the controller 39. This not only reduces the complexity and workload of manual operation, but also avoids errors caused by human factors.
[0049] Specifically, the controller 39 controls the actions of the three-way valve 36 and the suction and discharge pump 33, which can be highly adapted to the original workstation (i.e. the first sample determination tube assembly), ensuring that the entire analysis process remains consistent with the original configuration efficiency.
[0050] Specifically, the suction and discharge pump 33 is used to realize the suction and discharge action of the sample and the quantitative determination of the sample, which can adopt a device similar to the dosino liquid adding unit function of Swiss Wante.
[0051] Among them, the related setting of the liquid inlet and outlet mechanism cooperating with the sample needle 11 is explained as follows:
[0052] In the optional scheme of the present embodiment, it is more preferred that, as shown in Figure 1 As shown, the liquid inlet and outlet mechanism further comprises an automatic sampler, and the automatic sampler has a rotating turntable 10. For the first sample determination, a plurality of sample bottles are arranged on the turntable 10. For the second sample determination, a waste liquid cup 38 is arranged on the turntable 10. During the first sample determination, the plurality of sample bottles are placed on the turntable 10 of the automatic sampler, which can realize automatic continuous sampling, which means that the instrument can sequentially suck samples from different sample bottles for analysis according to the preset program, without manual replacement of samples. During the second sample determination, the waste liquid cup 38 is arranged on the turntable 10, which facilitates the collection of waste liquid. In the complex sample pretreatment process, such as the washing of the enrichment column 31 and the flushing of the sample needle 11, a large amount of waste liquid will be generated. By placing the waste liquid cup 38 on the turntable 10 of the automatic sampler, the waste liquid can be directly discharged into the waste liquid cup 38 through the sample needle 11 and other components, realizing centralized collection.
[0053] Among them, the related setting of the chromatographic analysis device is explained as follows:
[0054] In the optional scheme of the present embodiment, it is more preferred that, as shown in Figure 1As shown, the chromatographic analysis device comprises an eluent supply device and a chromatographic separation and detection device; the eluent supply device comprises an eluent bottle 50 and an eluent supply pump 51; the eluent bottle 50 is used to contain eluent; the inlet end of the eluent supply pump 51 is located in the eluent bottle 50, and the outlet end of the eluent supply pump is used to communicate with the fifth connecting port of the six-way valve 40; the chromatographic separation and detection device comprises a chromatographic separation column 60 and a detector 62 connected and communicated in sequence; the inlet end of the chromatographic separation column 60 communicates with the sixth connecting port of the six-way valve 40. The eluent supply pump 51 in the eluent supply device can accurately control the supply of eluent, and through the eluent supply pump 51, the flow of eluent can be flexibly adjusted according to different sample types and analysis requirements; the eluent supply device and the chromatographic separation and detection device closely cooperate in the chromatographic analysis process, the eluent carries the sample into the chromatographic separation column 60, and the separated ions are detected by the detector 62, and the whole process is a coherent system. This cooperative working mode can ensure the efficiency and accuracy of the analysis process.
[0055] In the optional scheme of the present embodiment, more preferably, as shown in Figure 1 As shown, the chromatographic separation and detection device further comprises an inhibitor 61 arranged between the chromatographic separation column 60 and the detector 62. The inhibitor 61 can eliminate CO2, reduce detection interference factors, and improve measurement accuracy.
[0056] Among them, the other related settings are as follows:
[0057] In the optional scheme of the present embodiment, more preferably, the first quantitative ring 23 is a 20uL quantitative ring, and the second quantitative ring 352 is a 1mL quantitative ring. The 20uL quantitative ring is suitable for measuring samples of normal concentration, and this volume is relatively small, which is very suitable for samples with high ion concentration or only a small amount of sample injection can meet the detection requirements; the 1mL quantitative ring has a large capacity, which is mainly used for enriching low-concentration samples. When it is necessary to detect trace ions (such as heavy metal ions) in environmental water samples or trace ion components in biological samples, a larger sample injection amount can ensure that enough target ions are introduced into the chromatographic analysis device; for complex samples, which may contain a variety of ion components, some of which have large concentration differences, the 1mL quantitative ring can contain as many ion components as possible in one injection, so that the sample can be comprehensively analyzed in the chromatographic separation and detection process.
[0058] In the optional solution of the embodiment, preferably, the connection between the first sample measuring tube assembly and the six-way valve 40 and the sampling needle 11 and the connection between the second sample measuring tube assembly and the six-way valve 40 and the sampling needle 11 are both connected by a union joint. In the assembly process of the ion chromatograph, the use of the union joint can make the connection between the first sample measuring tube assembly, the second sample measuring tube assembly, the six-way valve 40 and the sampling needle 11 more convenient, and the technician can easily complete the assembly and switching of the components without the need for complex tools or professional connection skills.
[0059] Specifically, the use of the union joint can be freely switched with the original configuration.
[0060] In the optional solution of the embodiment, preferably, the material of each position in contact with the measuring sample is selected according to the characteristics of the measuring sample and does not affect the measurement results. By selecting the appropriate material according to the characteristics of different samples, the ion chromatograph can be compatible with more types of samples, and the accuracy of the detection and measurement results can be ensured.
[0061] Specifically, the second sample measuring tube assembly is a configuration setting used to replace the first sample measuring tube assembly on the basis of the original equipment, so as to be applicable to special cases where the original equipment cannot be measured. Except for the second sample measuring tube assembly, the other parts can be the same as the original equipment.
[0062] The principle and implementation mode of the specific examples are described in the utility model, and the above embodiment is only used to help understand the method and core idea of the utility model; at the same time, for the general technical personnel in the field, according to the idea of the utility model, the specific implementation mode and the application range will be changed. In conclusion, the content of the specification should not be understood as the limitation of the utility model.
Claims
1. An ion chromatograph characterized by: The six-way valve, the chromatographic analysis device and the liquid inlet and outlet mechanism are included. The six-way valve has a first connecting port, a second connecting port, a third connecting port, a fourth connecting port, a fifth connecting port and a sixth connecting port which can communicate with each other. The chromatographic analysis device has a washing liquid outlet and a detection inlet; the washing liquid outlet communicates with the fifth connecting port of the six-way valve, and the detection inlet communicates with the sixth connecting port of the six-way valve. The liquid inlet and outlet mechanism includes a sample injection needle, a first sample determination tube assembly and a second sample determination tube assembly. For the first sample determination, the liquid inlet and outlet mechanism includes the sample injection needle and the first sample determination tube assembly; the first sample determination tube assembly includes a first sample injection tube, a first quantitative ring and a first liquid outlet tube; the inlet end of the sample injection needle is used to communicate with a sample bottle containing a sample, and the outlet end of the sample injection needle communicates with the inlet end of the first sample injection tube; the outlet end of the first sample injection tube is used to communicate with the first connecting port of the six-way valve, and a sample injection peristaltic pump is connected to the first sample injection tube; one end of the first quantitative ring communicates with the third connecting port of the six-way valve, and the other end of the first quantitative ring communicates with the fourth connecting port of the six-way valve; the inlet end of the first liquid outlet tube communicates with the second connecting port of the six-way valve. For the second sample determination, the liquid inlet and outlet mechanism includes the sample injection needle and the second sample determination tube assembly; the second sample determination tube assembly includes an enrichment column, a washing bottle, a suction pump, a first branch tube, a second branch tube, a second quantitative ring, a buffer tube, a three-way valve, a second sample injection tube and a second liquid outlet tube; one end of the enrichment column communicates with the third connecting port of the six-way valve, and the other end of the enrichment column communicates with the fourth connecting port of the six-way valve; the washing bottle is used to store ultrapure water; one end of the suction pump communicates with the inside of the washing bottle, and the other end of the suction pump is connected with the first branch tube and the second branch tube respectively; the single connecting port of the suction pump can form a suction port or a discharge port; the three-way valve has a first connecting port, a second connecting port and a third connecting port; the other end of the first branch tube communicates with the second connecting port, the other end of the second branch tube communicates with the third connecting port, the second quantitative ring and the buffer tube are connected in sequence to the second branch tube, the second quantitative ring is located on the side close to the three-way valve, and the capacity of the second quantitative ring is greater than that of the first quantitative ring; one end of the second sample injection tube communicates with the first connecting port of the three-way valve, and the other end of the second sample injection tube is used to communicate with the second connecting port of the six-way valve; one end of the second liquid outlet tube is used to communicate with the first connecting port of the six-way valve, and the other end of the second liquid outlet tube is used to communicate with one end of the sample injection needle, and the other end of the sample injection needle is used to communicate with a waste liquid cup.
2. The ion chromatograph of claim 1, wherein: The second sample determination tube assembly further includes a purification column connected to the first branch tube.
3. The ion chromatograph of claim 1, wherein: The first sample assay tube assembly further comprises an ultrafiltration assembly arranged on the first sample inlet tube; the ultrafiltration assembly is located between the sample inlet peristaltic pump and the first connecting port of the six-way valve.
4. The ion chromatograph of claim 1, wherein: The liquid inlet and outlet mechanism further comprises an automatic sample injector, the automatic sample injector having a rotating turntable; For the first sample assay, a plurality of sample bottles are arranged on the turntable; For the second sample assay, the waste liquid cup is arranged on the turntable.
5. The ion chromatograph of claim 1, wherein: The second sample assay tube assembly further comprises a controller, the controller being in communication connection with the three-way valve and the pump.
6. The ion chromatograph of claim 1, wherein: The chromatographic analysis device comprises an eluent supply device and a chromatographic separation and detection device; The eluent supply device comprises an eluent bottle and an eluent supply pump; the eluent bottle is used for containing eluent; the inlet end of the eluent supply pump is located in the eluent bottle, and the outlet end of the eluent supply pump is used for being in communication with the fifth connecting port of the six-way valve; The chromatographic separation and detection device comprises a chromatographic separation column and a detector connected and communicated in sequence; the inlet end of the chromatographic separation column is in communication with the sixth connecting port of the six-way valve.
7. The ion chromatograph of claim 1, wherein: The first quantitative ring is a 20uL quantitative ring, and the second quantitative ring is a 1mL quantitative ring.
8. The ion chromatograph of claim 1, wherein: The connections between the first sample assay tube assembly and the six-way valve and the sample inlet needle and the connections between the second sample assay tube assembly and the six-way valve and the sample inlet needle all adopt union joints.
9. The ion chromatograph of claim 1, wherein: The materials of all positions in contact with the assay sample are materials that do not affect the assay results according to the characteristics of the assay sample.
10. The ion chromatograph of claim 6, wherein: The chromatographic separation and detection device further comprises an inhibitor arranged between the chromatographic separation column and the detector.