Raw material inspection device for flunarizine hydrochloride capsule production

By designing a raw material testing device for the production of flunarizine hydrochloride capsules, a quantitative injection and precipitation reaction were achieved using an electric heating tube and an electric push rod. This solved the problem of inconsistent test results for flunarizine hydrochloride raw materials and ensured the authority and accuracy of raw material purity testing.

CN223664459UActive Publication Date: 2025-12-12ZHENGZHOU KAILI PHARM CO LTD
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Patent Information

Application Number
CN202423117140.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-17
Publication Date
2025-12-12
Estimated Expiration
2034-12-17

AI Technical Summary

Technical Problem

In existing technologies, the test results for flunarizine hydrochloride raw materials are inconsistent due to differences in temperature, time, and operators, making it difficult to achieve accurate comparative testing of the same raw material at the same time, thus affecting the authority of the test.

Method used

A raw material inspection device for the production of flunarizine hydrochloride capsules was designed. The device controls the temperature through an electric heating tube, uses an electric push rod and drive device to realize quantitative injection and precipitation reaction, and combines a weight sensor to detect precipitated particles to ensure the uniformity of the same raw material.

Benefits of technology

This ensures consistency in the results of multiple tests on the same raw material, enhances the authority and accuracy of the inspection, and guarantees the uniformity of the raw material purity.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a raw material inspection device for flunarizine hydrochloride capsule production, which relates to the technical field of capsule production and comprises an inspection box, an electric heating tube is mounted at the bottom of the inspection box, a temperature sensor is mounted at the bottom end of an inner cavity of the inspection box, and an installation ring is mounted on the upper portion of the inner wall of the inspection box. A sealing cover is mounted at an opening in the upper end of the mounting ring, a driving device is mounted in the center of the upper end of the sealing cover, a feeding pipeline is mounted at the position, on the left side of the driving device, of the upper end of the sealing cover, and a liquid injection pipeline is mounted at the position, on the right side of the driving device, of the upper end of the sealing cover. By arranging a series of structures, the weight of particles in the containing structure is transmitted to an external control platform and compared, then whether the internal purity of liquid raw materials is evenly distributed or not is detected, and the inspection authority is enhanced through comparison inspection.
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Description

TECHNICAL FIELD

[0001] The utility model relates to capsule production technical field, concretely is a fluorine guanri xiazhi capsule production with raw material testing device. BACKGROUND

[0002] Flunarizine hydrochloride is a kind of vasodilator, belongs to selective calcium antagonists, the chemical raw material of flunarizine hydrochloride usually includes 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid 3-methyl ester 5-ethyl ester (guanri xiazhi), hydrochloric acid etc., the purity and quality of these chemical raw materials are crucial to synthesis high-quality flunarizine hydrochloride.

[0003] When the raw material of flunarizine hydrochloride is detected, multiple sampling inspection is often carried out in a larger raw material warehouse to ensure the authenticity of raw material inspection, but the temperature, time and operator are different each time, so that the test result is deviated, and it is difficult to compare and test the same raw material at the same time, compared with single test of a raw material, comparative test can better reflect the authority of raw material test. UTILITY MODEL CONTENTS

[0004] The utility model aims at providing a kind of flunarizine hydrochloride capsule production with raw material testing device to solve the problems raised in the above background.

[0005] To achieve the above object, the utility model provides the following technical scheme: a kind of flunarizine hydrochloride capsule production with raw material testing device, including test box, the bottom of the test box is equipped with electric heating tube, temperature sensor is installed at the bottom end of the internal cavity of the test box, installation ring is installed on the inner wall upper portion of the test box, the upper end opening of the installation ring is equipped with cover, the upper end center position of the cover is equipped with driving device, the position of the cover upper end left side of driving device is equipped with inlet pipe, the position of the right side of driving device and the upper end of cover is equipped with liquid injection pipe, the inside bottom of the test box is equipped with second electric push rod, the upper of the second electric push rod is equipped with support plate, the upper end of the support plate is equipped with test disc, the lower end of driving device is connected with the upper end of test disc by pivot, the outer side wall of test disc is equipped with multiple sector blocks in array, slidingly connected with receiving structure between adjacent two sector blocks, the bottom of liquid injection pipe is on the same vertical line with any one receiving structure through liquid injection port, the position of the bottom of test box outside second electric push rod is equipped with multiple first electric push rods in array, the upper end of the first electric push rod is equipped with weight sensor, the upper end of weight sensor and the lower end of receiving structure are connected, multiple weight sensors, electric heating tube and temperature sensor are electrically connected with external control platform.

[0006] Preferably, a limiting frame is arranged between the two fan-shaped blocks, and the limiting frame has a height smaller than that of the fan-shaped blocks.

[0007] Preferably, the receiving structure comprises a reaction tank, a limiting plate and a sliding block, the upper end of the limiting frame is in contact with the edge of the lower end of the limiting plate, the center of the lower end of the limiting plate is provided with the sliding block, the sliding block is in sliding connection with the inner wall of the limiting frame, the upper end of the limiting plate is provided with the reaction tank, the reaction tank extends to the inside of the sliding block, and the lower end of the sliding block is connected with the weight sensor.

[0008] Preferably, a plurality of air holes are arranged on the upper end of the mounting ring.

[0009] Preferably, the outer surfaces of the plurality of fan-shaped blocks are in sliding connection with a lifting ring, the inner wall of the lifting ring is fixedly connected with the edge of a supporting plate, the upper end of the supporting plate is in contact with the inspection disc and the lower end of the fan-shaped block, a plurality of through grooves are arranged on the outer circle of the supporting plate, and the through grooves are matched with the first electric push rod in number and position.

[0010] Preferably, a plurality of through holes are arranged on the upper end of the lifting ring, a plurality of guide sliding rods are arranged on the inside bottom end of the inspection box and located outside the first electric push rod, and the plurality of guide sliding rods are in sliding connection with the plurality of through holes in sequence.

[0011] Preferably, a display screen is arranged on the outer surface of the inspection box, and the display screen is electrically connected with an external control platform.

[0012] Compared with the prior art, the utility model has the beneficial effects that:

[0013] 1、The raw material testing device for fluorine guanxi lysine hydrochloride capsule production, through the liquid material that needs to be tested is drawn to the liquid injection port through the liquid injection pipeline, the testing disc is driven to ascend by the second electric push rod, the storage structure is synchronously ascended by the first electric push rod, and the storage structure is located below the liquid injection port, the quantitative liquid material is injected into the storage structure through the liquid injection port, the driving device is started to drive the rotating shaft and the testing disc to rotate, so that the other storage structure is rotated to below the liquid injection port, the operation is repeated in turn, so that all the storage structures are injected with quantitative liquid material, at this time, the liquid material in the storage structure is part of the same material to be detected, and then the precipitator is injected into the storage structure through the feeding pipeline, it should be noted that the type of the precipitator needs to be matched with the type of the liquid material, at this time, the liquid material will be combined into particles and precipitated by the precipitator, the testing disc and the storage structure are moved to the bottom of the testing box by the synchronous descending of the first electric push rod and the second electric push rod, the electric heating pipe is started, the electric heating pipe can raise the temperature in the testing box, and the moisture in the storage structure is evaporated, at this time, the storage structure will leave the material particles that cannot be evaporated, at this time, only the first electric push rod drives the storage structure to ascend alone, the weight of the storage structure is detected by the weight sensor, and the weight is removed, finally, the weight of the particles in the storage structure is transmitted to the external control platform, and comparison is made, so as to detect whether the purity of the liquid material is uniformly distributed and the like, and the authority of the test is enhanced by comparison test.

[0014] 2、The raw material testing device for fluorine guanxi lysine hydrochloride capsule production, the guide sliding rod is slidably connected with the lifting ring through the through hole, and can guide and limit the movement track of the lifting ring during the lifting movement of the lifting ring. DETAILED DESCRIPTION

[0015] Fig. 1 It is a structure schematic view of the whole structure of the utility model;

[0016] Fig. 2 It is a structure schematic view of the utility model's cover and mounting ring;

[0017] Fig. 3 It is an internal structure schematic view of the utility model's testing box;

[0018] Fig. 4 It is a related structure disassembly structure diagram of the utility model's testing disc.

[0019] In the figure: 1, test box; 2, display screen; 3, mounting ring; 4, cover; 5, liquid injection pipeline; 6, feeding pipeline; 7, driving device; 8, air vent; 9, liquid injection port; 10, rotating shaft; 11, test disc; 12, guide slide rod; 13, first electric push rod; 14, second electric push rod; 15, sector block; 16, limiting frame; 17, storage structure; 1701, reaction tank; 1702, limiting plate; 1703, sliding block; 18, through groove; 19, temperature sensor; 20, lifting ring; 21, through hole; 22, support plate; 23, weight sensor. DETAILED DESCRIPTION

[0020] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all the other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the utility model.

[0021] In the description of the utility model, it should be noted that the terms "upper", "lower", "inner", "outer", "front end", "rear end", "two ends", "one end", "the other end" and the like indicate the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the utility model and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as limiting the utility model. In addition, the terms "first" and "second" are only for the purpose of description, and cannot be understood as indicating or implying relative importance.

[0022] As Figs. 1 to 4As shown, the raw material testing device for producing flunarizine hydrochloride capsules of the embodiment, including the test box 1, the bottom of the test box 1 is installed with an electric heating tube, the electric heating tube can change the temperature inside the test box 1, the bottom end of the internal cavity of the test box 1 is installed with a temperature sensor 19, the temperature sensor 19 is internally provided with a temperature range, when the temperature inside the test box 1 reaches the predetermined temperature, the temperature sensor 19 will transmit an electrical signal to the external control platform, at this time the external control platform will stop the operation of the electric heating tube, the inner wall of the test box 1 is installed with a mounting ring 3 at the upper part, the mounting ring 3 is fixedly connected between the test box 1, the mounting ring 3 is installed with a cover 4 at the opening of the upper end, the cover 4 and the mounting ring 3 are in detachable connection relationship, such as threaded connection, the upper end center position of the cover 4 is installed with a driving device 7, the driving device 7 is a common servo motor on the market, and is electrically connected with the external control platform, the cover 4 is installed with an inlet pipe 6 at the position of the left side of the driving device 7 at the upper end, the driving device 7 is installed with a liquid injection pipe 5 at the position of the right side and the upper end of the cover 4, the liquid injection pipe 5 is used for injecting the liquid raw material to be detected, the inlet pipe 6 is used for putting other materials which can have a precipitation reaction with the liquid raw material, and the inlet pipe 6 and the liquid injection pipe 5 are symmetrically installed with the driving device 7 as the center, the inside bottom of the test box 1 is installed with a second electric push rod 14, the second electric push rod 14 is located at the center position of the test box 1, the upper side of the second electric push rod 14 is installed with a supporting plate 22, the upper end of the supporting plate 22 is installed with a test disc 11, the second electric push rod 14 can drive the test disc 11 to move up and down, the lower end of the driving device 7 is connected with the upper end of the test disc 11 through the shaft 10, the driving device 7 can drive the test disc 11 to rotate, the outer side wall of the test disc 11 is installed with a plurality of fan-shaped blocks 15 in array, a receiving structure 17 is slidably connected between any two adjacent fan-shaped blocks 15, the receiving structure 17 is in sliding connection relationship with the fan-shaped block 15, the bottom end of the liquid injection pipe 5 is in the same vertical line with any one receiving structure 17 through the liquid injection port 9, the liquid injection pipe 5 and the inlet pipe 6 are symmetrically installed with each other, so that the inlet pipe 6 is also in the same vertical line with any one receiving structure 17, a plurality of first electric push rods 13 are arrayed and installed at the position outside the second electric push rod 14 at the bottom end of the test box 1, the plurality of first electric push rods 13 are circularly arrayed and installed, the upper end of the first electric push rod 13 is installed with a weight sensor 23, the upper end of the weight sensor 23 is connected with the lower end of the receiving structure 17, the height position of the receiving structure 17 can be individually changed through the first electric push rod 13, the plurality of weight sensors 23, the electric heating tube and the temperature sensor 19 are electrically connected with the external control platform, the liquid raw material is injected into the receiving structure 17 through the liquid injection pipe 5, the precipitant is put into the receiving structure 17 through the inlet pipe 6, so that the liquid raw material produces precipitated particles, it should be noted that the type of precipitant needs to be adapted to the type of liquid raw material, at this time the liquid raw material will be combined into particles by the precipitant and precipitated,For example, hydrochloric acid can react with calcium hydroxide to generate calcium chloride and water, the solubility of calcium chloride in water is small, and it will exist in the form of precipitation, and then through heating, the water can be evaporated and calcium chloride particles are left.

[0023] Specifically, a limiting frame 16 is arranged between two fan-shaped blocks 15, the height of the limiting frame 16 is smaller than the height of the fan-shaped block 15, the receiving structure 17 includes a reaction tank 1701, a limiting plate 1702 and a sliding block 1703, the upper end of the limiting frame 16 is in contact with the edge of the lower end of the limiting plate 1702, the center of the lower end of the limiting plate 1702 is provided with the sliding block 1703, the sliding block 1703 is in sliding connection with the inner wall of the limiting frame 16, the upper end of the limiting plate 1702 is provided with the reaction tank 1701, the reaction tank 1701 extends to the inside of the sliding block 1703, the lower end of the sliding block 1703 is connected with the weight sensor 23, the limiting frame 16 and the limiting plate 1702 are used in cooperation, in the normal state, the limiting frame 16 can support the limiting plate 1702 and the sliding block 1703, when the first electric push rod 13 rises, the limiting plate 1702 and the sliding block 1703 will be separated from the limiting frame 16 and move upward alone, the surface of the reaction tank 1701 is paved with an anti-corrosion film, and the inside is used for chemical reaction of liquid raw materials.

[0024] Further, the upper end of the mounting ring 3 is provided with a plurality of air holes 8, and the air holes 8 are used to discharge the evaporated water vapor.

[0025] Further, the outer surfaces of the plurality of fan-shaped blocks 15 are jointly and slidably connected with a lifting ring 20, the inner wall of the lifting ring 20 is fixedly connected with the edge of the supporting plate 22, the upper end of the supporting plate 22 is in contact with the lower end of the inspection disc 11 and the fan-shaped block 15, the outer circle of the supporting plate 22 is provided with a plurality of through grooves 18, the through grooves 18 are matched with the first electric push rod 13 in number and position, the upper end of the lifting ring 20 is provided with a plurality of through holes 21, the inside bottom end of the inspection box 1 and located at the position outside the first electric push rod 13 is provided with a plurality of guide sliding rods 12, the plurality of guide sliding rods 12 are sequentially and slidably connected with the plurality of through holes 21, the guide sliding rod 12 is slidably connected with the lifting ring 20 through the through hole 21, can guide and limit the movement track of the lifting ring 20 in the lifting movement process of the lifting ring 20, and the inspection disc 11 can rotate in the inside of the lifting ring 20.

[0026] Further, the outer surface of the inspection box 1 is provided with a display screen 2, the display screen 2 is electrically connected with the external control platform, and the display screen 2 can display the heating time in the inside of the inspection box 1, so as to facilitate the user to observe.

[0027] The use method of the embodiment is: the liquid raw material to be tested is drawn to the liquid injection port 9 through the liquid injection pipeline 5, the test disc 11 is driven to rise by the second electric push rod 14, the first electric push rod 13 drives the storage structure 17 to rise synchronously, and the storage structure 17 is located directly below the liquid injection port 9, the quantitative liquid raw material is injected into the storage structure 17 through the liquid injection port 9, the driving device 7 is started to drive the rotating shaft 10 and the test disc 11 to rotate, so that the other storage structure 17 is rotated to be directly below the liquid injection port 9, the operation is repeated in sequence, so that all the storage structures 17 are injected with quantitative liquid raw material, at this time, the liquid raw material in the storage structure 17 is part of the same to-be-tested raw material, and then the precipitator is injected into the plurality of storage structures 17 through the feeding pipeline 6 in sequence, it should be noted that the type of the precipitator needs to be matched with the type of the liquid raw material, at this time, the liquid raw material will be combined into particles by the precipitator and precipitated, the test disc 11 and the storage structure 17 are moved to the bottom of the test box 1 by the synchronous descending of the first electric push rod 13 and the second electric push rod 14, the electric heating pipe is started, the electric heating pipe can raise the temperature in the test box 1 and evaporate the moisture in the storage structure 17, at this time, the storage structure 17 will leave the raw material particles that cannot be evaporated, at this time, only the plurality of first electric push rods 13 drive the storage structure 17 to rise alone, the weight of the storage structure 17 is detected by the weight sensor 23 and is removed, finally, the weight of the particles in the storage structure 17 is transmitted to the external control platform and is compared, so as to detect whether the purity of the liquid raw material is uniformly distributed and the like, and the comparison test can enhance the authority of the test.

[0028] Finally, it should be noted that: the above only describes preferred embodiments of the present application and is not intended to limit the present application, although the present application has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions recorded in the foregoing embodiments, or make equivalent replacement for some technical features. Any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present application shall be included in the protection scope of the present application.

Claims

1. A raw material inspection device for flunarizine hydrochloride capsule production, comprising an inspection box (1), characterized in that: The bottom of the test box (1) is provided with an electric heating pipe, and the bottom end of the internal cavity of the test box (1) is provided with a temperature sensor (19); the upper end of the inner wall of the test box (1) is provided with a mounting ring (3), and the opening of the upper end of the mounting ring (3) is provided with a cover (4); the center of the upper end of the cover (4) is provided with a driving device (7); the left side of the upper end of the cover (4) is provided with an inlet pipe (6); the right side of the driving device (7) and the upper end of the cover (4) are provided with a liquid injection pipe (5); the bottom end of the test box (1) is provided with a second electric push rod (14); the upper end of the second electric push rod (14) is provided with a support plate (22); the upper end of the support plate (22) is provided with a test disc (11); the lower end of the driving device (7) is connected with the upper end of the test disc (11) through a rotating shaft (10); the outer side wall of the test disc (11) is provided with a plurality of fan-shaped blocks (15); two adjacent fan-shaped blocks (15) are slidably connected with a receiving structure (17); the bottom end of the liquid injection pipe (5) is in the same vertical line with any one receiving structure (17) through a liquid injection port (9); the bottom end of the test box (1) is provided with a plurality of first electric push rods (13) outside the second electric push rod (14); the upper end of the first electric push rod (13) is provided with a weight sensor (23); the upper end of the weight sensor (23) is connected with the lower end of the receiving structure (17); the weight sensor (23), the electric heating pipe and the temperature sensor (19) are electrically connected with an external control platform.

2. The flunarizine hydrochloride capsule production raw material inspection device according to claim 1, characterized in that: A limiting frame (16) is arranged between two fan-shaped blocks (15), and the height of the limiting frame (16) is smaller than the height of the fan-shaped block (15).

3. The flunarizine hydrochloride capsule production raw material inspection device according to claim 2, characterized in that: The receiving structure (17) comprises a reaction tank (1701), a limiting plate (1702) and a sliding block (1703); the upper end of the limiting frame (16) is connected with the edge of the lower end of the limiting plate (1702); the center of the lower end of the limiting plate (1702) is provided with the sliding block (1703); the sliding block (1703) is slidably connected with the inner wall of the limiting frame (16); the upper end of the limiting plate (1702) is provided with the reaction tank (1701); the reaction tank (1701) extends to the inside of the sliding block (1703); and the lower end of the sliding block (1703) is connected with the weight sensor (23).

4. The flunarizine hydrochloride capsule production raw material inspection device according to claim 1, characterized in that: A plurality of air holes (8) are arranged on the upper end of the mounting ring (3).

5. The flunarizine hydrochloride capsule production raw material inspection device according to claim 1, characterized in that: An elevating ring (20) is slidably connected with the outer surfaces of a plurality of fan-shaped blocks (15); the inner wall of the elevating ring (20) is fixedly connected with the edge of the support plate (22); the upper end of the support plate (22) is in contact with the test disc (11) and the lower end of the fan-shaped block (15); a plurality of through grooves (18) are arranged on the outer ring of the support plate (22); and the through grooves (18) are matched with the first electric push rod (13) in number and position.

6. The flunarizine hydrochloride capsule production raw material inspection device according to claim 5, characterized in that: The upper end of the lifting ring (20) is provided with a plurality of through holes (21), and the inside bottom of the test box (1) and the position outside the first electric push rod (13) are provided with a plurality of guide sliding rods (12) in array, and the plurality of guide sliding rods (12) are sequentially and slidably connected with the plurality of through holes (21).

7. The flunarizine hydrochloride capsule production raw material inspection device according to claim 1, characterized in that: A display screen (2) is mounted on the outer surface of the test box (1), and the display screen (2) is electrically connected with an external control platform.