Mouse sweet water preference experiment device
By designing an intermittent cylinder and trough structure in the mouse sucrose preference test apparatus, the problem of water leakage in the water bottle was solved, thus ensuring the accuracy of experimental data and the convenience of drinking for the mice.
Patent Information
- Application Number
- CN202520251746.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-02-17
- Publication Date
- 2025-12-16
- Estimated Expiration
- 2035-02-17
AI Technical Summary
The water bottle in the existing mouse sucrose preference test apparatus is prone to leakage, which affects the accuracy of the experimental data.
Two first cylinders are designed and spaced apart in the horizontal direction. The side wall of the cylinder is provided with a first through hole and a tank. The opening of the tank is higher than the through hole. After the liquid flows, the liquid level in the tank is higher than the through hole, forming a stable liquid column to avoid leakage. The tank automatically replenishes the liquid to ensure the accuracy of the experimental data.
It effectively avoids leakage, improves the accuracy of experimental data, facilitates drinking by mice, has a reasonable structure, and reduces experimental errors.
Smart Images
Figure CN223667011U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to experimental device technical field, especially in mouse sugar water preference experiment device. BACKGROUND
[0002] Sugar water preference experiment is used to test the degree of mouse's sugar water preference, and is used to obtain a test index reflecting the loss of pleasure of mouse, wherein the loss of pleasure refers to the lack of interest in the stimulation of food, sex and other rewards, and the index is used as a core index for evaluating emotional disorder disease models such as a depression mouse model.
[0003] The water bottle in the existing mouse sugar water preference experiment device is divided into two styles of vacuum type and ball type. The vacuum type water bottle has a small hole in the spout part after water is filled in the bottle, and water enters the mouse's mouth when the mouse licks the spout, but water will leak from the spout when the water bottle is bumped by external force or hit by the mouse, and even moving the water bottle will cause water leakage. The ball type is provided with a ball at the spout, and water enters the mouse's mouth along the ball when the mouse licks the ball, but when the water volume is small, i.e. the water pressure is small, water will leak from the gap between the ball and the spout, thereby affecting the accuracy of experimental data. SUMMARY
[0004] The main purpose of the utility model is to provide a mouse sugar water preference experiment device, which aims to solve the problem of water leakage in the existing mouse sugar water preference experiment device.
[0005] To achieve the above purpose, the utility model provides a mouse sugar water preference experiment device, which comprises two first cylinders arranged at intervals in the horizontal direction, and the two first cylinders are used for storing liquid with different concentrations, respectively, and a first through hole is formed in the side wall of each first cylinder for liquid outflow.
[0006] The mouse sugar water preference experiment device further comprises two groove bodies arranged on the side walls of the two first cylinders, respectively, and each groove body is arranged corresponding to each first through hole, and the groove opening of the groove body is arranged upward and the height of the groove opening of the groove body is higher than the height of the first through hole, so that the liquid level in the groove body is higher than the first through hole when the liquid stops flowing.
[0007] In an embodiment, the two first cylinders have two side walls arranged oppositely, wherein the two side walls arranged oppositely are arranged closely to form a second cylinder together.
[0008] In an embodiment, the upper end of the second cylinder has an opening to communicate the upper ends of the two first cylinders with the outside.
[0009] The mouse sugar water preference experiment device further comprises a first cover body, which covers the opening.
[0010] In an embodiment, the first cover body is provided with two second through holes corresponding to the two first cylinder bodies.
[0011] The mouse sugar water preference experiment device further comprises two second cover bodies, each of which covers a second through hole, and each of the second cover bodies is further provided with a third through hole.
[0012] In an embodiment, the third through hole has a diameter d, which satisfies the following condition:
[0013]
[0014] wherein η is the viscosity of air, L is the thickness of the second cover body in the vertical direction, Q is the flow rate of the liquid in the first cylinder body, ρ is the density of the liquid in the first cylinder body, g is the acceleration of gravity, H is the height of the liquid surface in the first cylinder body, h1 is the height of the center of the first through hole, and h2 is the size of the liquid surface in the groove body in the vertical direction from the center of the first through hole.
[0015] In an embodiment, a sealing ring is arranged between the first cover body and the second cylinder body.
[0016] In an embodiment, the second cylinder body is provided with an inverted scale on the cylinder wall corresponding to the opposite side walls, which is used to measure the volume of the liquid flowing out of the two first cylinder bodies.
[0017] In an embodiment, the mouse sugar water preference experiment device further comprises a rotating device, which comprises a seat body and a driving rod arranged on the seat body, and the driving rod is drivingly connected to the bottom of the second cylinder body, so as to drive the second cylinder body to rotate.
[0018] In an embodiment, the rotating device further comprises a control module, which is arranged on the seat body and is electrically connected to the driving rod, so as to control the rotation parameters of the second cylinder body.
[0019] In an embodiment, the rotating device further comprises an adsorption part, which is arranged below the seat body, so as to position the seat body.
[0020] The technical solution provided by this utility model, by setting up the tank and the first through hole, ensures that all flowing liquid is collected by the tank, preventing leakage. Furthermore, the height of the tank opening is higher than the height of the first through hole. Therefore, as the liquid level in the tank gradually rises above the first through hole, the air pressure inside the first cylinder gradually decreases, and the height difference between the liquid level in the first cylinder and the liquid level in the tank also gradually decreases. Eventually, the entire system stabilizes, and the liquid stops flowing. This allows for automatic replenishment of the liquid in the tank when the mice consume it, ensuring that the liquid does not overflow, further improving the accuracy of experimental data. Simultaneously, the tank design makes it easier for mice to drink from, resulting in a more rational structure. Attached Figure Description
[0021] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on the structures shown in these drawings without creative effort.
[0022] Figure 1 A schematic diagram of an embodiment of the mouse sucrose preference experimental device provided by this utility model;
[0023] Figure 2 for Figure 1 Front view of the first and second covers;
[0024] Figure 3 for Figure 1 Side view of the second cylinder.
[0025] Explanation of icon numbers:
[0026] 1000. Mouse sucrose preference test apparatus; 1. Second cylinder; 11. First cylinder; 2. Tank; 21. First through hole; 3. First cover; 31. Second through hole; 4. Second cover; 41. Third through hole; 5. Rotating device; 51. Base; 52. Drive rod; 53. Control module; 54. Battery; 55. Charging module; 6. Scale.
[0027] The realization of the purpose, functional features and advantages of this utility model will be further explained in conjunction with the embodiments and with reference to the accompanying drawings. Detailed Implementation
[0028] Clearly and completely describe the technical solutions in the embodiments of the present application in combination with the drawings in the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of the present application.
[0029] It should be noted that if the embodiments of the present application involve directional indications (such as up, down, left, right, front, back, etc.), the directional indications are only used to explain the relative positional relationship, movement condition, etc. between the components in a certain specific posture, and if the specific posture changes, the directional indications also change accordingly.
[0030] In addition, if the embodiments of the present application involve descriptions such as "first", "second", etc., the descriptions of "first", "second", etc. are only for description purposes, and cannot be understood as indicating or implying the relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features limited by "first" and "second" can explicitly or implicitly include at least one of the features. In addition, "and / or" or "and / or" appearing throughout the text means that the three parallel schemes are included, for example, "A and / or B" includes A scheme, or B scheme, or A and B simultaneously satisfy the scheme. In addition, the technical solutions of each embodiment can be combined with each other, but it must be based on the fact that a person skilled in the art can realize it, and when the combination of technical solutions appears contradictory or unachievable, it should be considered that the combination of technical solutions does not exist, and is not within the scope of protection required by the present application.
[0031] The sugar water preference experiment is an experiment for testing the degree of preference of mice for sugar water, and is used to obtain a test index reflecting the lack of pleasure of mice. The lack of pleasure refers to the lack of interest in the stimulation of food, sex, etc. The index is used as a core index for evaluating emotional disorder disease models such as a depression mouse model.
[0032] The water bottle in the existing mouse sugar water preference experiment device is divided into two styles of vacuum type and ball type. The vacuum type water bottle has a small hole in the spout part after water is filled in the bottle, and water enters the mouse's mouth when the mouse licks the spout, but water leaks from the spout when the water bottle is bumped by external force or hit by the mouse, and even moving the water bottle will cause water leakage. The ball type is provided with a ball at the spout, and water enters the mouse's mouth along the ball when the mouse licks the ball, but when the water quantity is small, i.e. the water pressure is small, water leaks from the gap between the ball and the spout, thereby affecting the accuracy of the experimental data.
[0033] The utility model discloses a mouse sugar water preference experiment device, which aims to solve the problem of water leakage in the existing mouse sugar water preference experiment device.
[0034] Please refer to Figure 1 And Figure 3 The utility model provides a mouse sugar water preference experiment device 1000, including two first cylinder bodies 11 that interval setting is in horizontal direction, two first cylinder body 11 is used for depositing different concentration liquid respectively, and the lateral wall of each first cylinder body 11 is equipped with first through -hole 21, for the liquid outflow, the mouse sugar water preference experiment device 1000 still includes two groove bodies 2 that are separately arranged on the lateral wall of two first cylinder body 11, each groove body 2 is set up to each first through -hole 21, and the height of the groove mouth of groove body 2 is higher than the height of first through -hole 21, so that after the liquid stops flowing, the liquid level in groove body 2 is higher than first through -hole 21.
[0035] The utility model provides a technical scheme, through setting up the groove body 2 and first through -hole 21, make the liquid that flows can all get the receiving of groove body 2, avoid the occurrence of the phenomenon of leakage. Further, the height of the groove mouth of groove body 2 is higher than the height of first through -hole 21, so that when the liquid level height in groove body 2 gradually is higher than first through -hole 21, the air pressure in first cylinder body 11 gradually reduces, and the height difference of the liquid level of first cylinder body 11 and groove body 2 is also gradually reducing, finally the whole system tends to be stable, and the liquid will not flow any more, and then when the mouse consumes the liquid in groove body 2, the automatic replenishment of the liquid in groove body 2 is realized, and the accuracy of experimental data is further improved. Meanwhile, the design of groove body 2 is more convenient for the mouse to drink, so that the structure is more reasonable.
[0036] It should be noted that the air pressure in the first cylinder body 11 is lower than the air pressure outside the cylinder, so that when the liquid in the first cylinder body 11 flows out to the groove body 2 and the liquid level in the groove body 2 is higher than the first through -hole 21, a stable liquid column will be formed in the first cylinder body 11. The liquid in the groove body 2 can be licked by the mouse. During the process of gradually consuming the liquid in the groove body 2, when the liquid level in the groove body 2 gradually decreases to the first through -hole 21 and has a tendency to be lower than the first through -hole 21, the liquid in the first cylinder body 11 will be replenished to the groove body 2, so that the liquid level in the groove body 2 is always higher than the first through -hole 21, and the automatic replenishment of the liquid in the groove body 2 is realized.
[0037] In an embodiment of the utility model, please refer to Figure 1, two of the first barrels 11 have two oppositely arranged side walls, wherein the two oppositely arranged side walls are closely arranged so that the two first barrels 11 together form a second barrel 1. In this way, by combining the two first barrels 11 into one, it is convenient to compare the liquids in the two barrels subsequently, and it is also convenient to store and arrange, thereby reducing the occupied space of the entire device. Specifically, the cross section of the two first barrels 11 is arranged in a semicircular shape, and the second barrel 1 is arranged in a cylindrical shape, and the two oppositely arranged side walls are rectangular side walls of a semicircular cylinder.
[0038] Further, the second barrel 1 is provided with an inverted scale 6 on the barrel wall corresponding to the opposite side wall, for measuring the volume of liquid flowing out of the two first barrels 11. In this way, the scale 6 can identify the volume of liquid in the two first barrels 11 at the same time, so as to directly measure the outflow of liquids of different concentrations, thereby improving the experimental efficiency and increasing the intuitiveness of the device.
[0039] Further, in order to facilitate the injection of liquid into the second barrel 1, the upper end of the second barrel 1 has an opening for communicating the upper ends of the two first barrels 11 with the outside; the mouse sugar water preference experiment device 1000 further comprises a first cover 3, and the first cover 3 is arranged on the opening. In this way, the two first barrels 11 share one first cover 3, which is simple in structure and convenient to operate.
[0040] Further, a sealing ring is arranged between the first cover 3 and the second barrel 1, which increases the sealing property of the second barrel 1 and ensures the stability of the internal air pressure of the barrel, so that there is always an air pressure difference between the inside and outside of the second barrel 1.
[0041] In order to facilitate the outflow of liquid in the second barrel 1, please refer to Figure 1 and Figure 2 , the first cover 3 is provided with two second through holes 31 corresponding to the two first barrels 11; the mouse sugar water preference experiment device 1000 further comprises two second covers 4, each of the second covers 4 is arranged on each of the second through holes 31, and the second cover 4 is further provided with a third through hole 41. By arranging two second through holes 31, liquid can be respectively delivered into the two first barrels 11, which is convenient to operate. By arranging a third through hole 41 on the second cover 4, the air pressure in the first barrel 11 increases slowly during the outflow of liquid, thereby being more conducive to the outflow of liquid, preventing the liquid from flowing out due to liquid tension, too small first through hole 21, etc. In a preferred embodiment, the second cover 4 is arranged as a rubber plug, thereby facilitating the opening and subsequent taking and placing.
[0042] Further, the diameter of the third through hole 41 in the two first cylinders 11 can be calculated according to the preset height of the liquid level in the tank 2 after stabilization, specifically, the diameter of the third through hole 41 is d, and the following conditions are met: wherein, η is the viscosity of air, L is the thickness of the second cover 4 in the vertical direction, Q is the flow rate of the liquid in the first cylinder 11, ρ is the density of the liquid in the first cylinder 11, g is the acceleration of gravity, H is the height of the liquid level in the first cylinder 11, h1 is the height of the center of the first through hole 21, and h2 is the size of the liquid level in the tank 2 to the center of the first through hole 21 in the vertical direction. In this way, by reasonably setting the size of the third through hole 41, the height of the liquid level in the tank 2 can be controlled, and the liquid in the first cylinder 11 can flow out smoothly, which ensures that the device does not leak water, and also meets the requirement that the mouse can always lick the liquid in the tank 2, thereby improving the accuracy of the experiment.
[0043] In an embodiment of the present application, referring to Figure 1 , the mouse sugar water preference experiment device 1000 further comprises a rotating device 5, the rotating device 5 comprises a seat body 51 and a driving rod 52 arranged on the seat body 51, and the driving rod 52 is drivingly connected to the bottom of the second cylinder 1 to drive the second cylinder 1 to rotate. In this way, during the experiment, by rotating the second cylinder 1, the mouse has approximately the same probability of encountering the two tanks 2 at the same position, thereby effectively reducing the influence of the mouse's position preference.
[0044] Further, the rotating device 5 further comprises a control module 53, the control module 53 is arranged on the seat body 51 and is electrically connected to the driving rod 52 to control the rotation parameters of the second cylinder 1. It can be understood that the rotation parameters include rotation speed, rotation time, rotation period, etc., which are not limited here. By reasonably controlling the rotation parameters of the second cylinder 1, the influence of the mouse's position preference can be further reduced, and the accuracy of the experiment can be improved.
[0045] Further, the rotating device 5 further comprises an adsorption part (not labeled in the figure), and the adsorption part (not labeled in the figure) is arranged below the seat body 51 to position the seat body 51. By arranging the adsorption part (not labeled in the figure), the stability of the device is improved, and the phenomenon that the device is knocked down by the mouse during the mouse drinking water is avoided.
[0046] It is worth mentioning that the rotating device 5 further comprises a battery 54 and a charging module 55, so that the device can be used for a long time.
[0047] The above merely illustrates the exemplary embodiments of the present application, and does not limit the patent scope of the present application, and any equivalent structural transformation or direct / indirect application in other related technical fields under the technical concept of the present application and by using the content of the present application specification and drawings are included in the patent protection scope of the present application.
Claims
1. A mouse sugar-water preference test apparatus, characterized by, Two first barrels are arranged in a horizontal direction, and the two first barrels are used for storing liquid with different concentrations, respectively, and a first through hole is arranged on a side wall of each first barrel for liquid flowing out; The mouse sugar water preference experiment device further comprises two groove bodies arranged on the side walls of the two first barrels, and each groove body is arranged corresponding to the first through hole, and the groove opening of the groove body is arranged upward and the height of the groove opening of the groove body is higher than the height of the first through hole, so that the liquid level in the groove body is higher than the first through hole after the liquid stops flowing.
2. The mouse sugar-water preference test apparatus of claim 1, wherein The two first barrels have two side walls arranged oppositely, wherein the two side walls arranged oppositely are arranged closely to form a second barrel together.
3. The mouse sugar-water preference apparatus of claim 2, wherein, An opening is arranged at the upper end of the second barrel to communicate the upper ends of the two first barrels with the outside. The mouse sugar water preference experiment device further comprises a first cover body arranged on the opening.
4. The mouse sugar-water preference apparatus of claim 3, wherein The first cover body is provided with two second through holes corresponding to the two first barrels. The mouse sugar water preference experiment device further comprises two second cover bodies, each of which is arranged on each second through hole, and a third through hole is further arranged on the second cover body.
5. The mouse sugar-water preference apparatus of claim 4, wherein, The diameter of the third through hole is d, which satisfies the following condition: Wherein, η is the viscosity of air, L is the thickness of the second cover body in the vertical direction, Q is the flow rate of the liquid in the first barrel, ρ is the density of the liquid in the first barrel, g is the acceleration of gravity, H is the height of the liquid surface in the first barrel, h1 is the height of the center of the first through hole, and h2 is the vertical dimension of the liquid surface in the groove body to the center of the first through hole.
6. The mouse sugar-water preference apparatus of claim 3, wherein A sealing ring is arranged between the first cover body and the second barrel.
7. The mouse sugar-water preference apparatus of claim 2, wherein An inverted scale is arranged on the barrel wall of the second barrel corresponding to the opposite side walls for measuring the volume of liquid flowing out of the two first barrels.
8. The mouse sugar-water preference apparatus of claim 2, wherein, The mouse sugar water preference experiment device further comprises a rotating device, which comprises a seat body and a driving rod arranged on the seat body, and the driving rod is drivingly connected with the bottom of the second barrel to drive the second barrel to rotate.
9. The mouse sugar-water preference apparatus of claim 8, wherein, The rotating device further comprises a control module arranged on the seat body and electrically connected with the driving rod to control the rotation parameters of the second barrel.
10. The mouse sugar-water preference apparatus of claim 8, wherein, The rotating device further comprises an adsorption part arranged below the seat body to position the seat body.