Centrifugal machine for cell separation

Abstract

The utility model relates to the technical field of centrifugal machines, and discloses a centrifugal machine for cell separation, which comprises a case, a test tube and a sealing cover, the bottom of the inner side of the case is fixedly connected with a motor, the output end of the motor is fixedly connected with a rotating table, and the periphery of the inner side of the rotating table is communicated with placing cylinders; and sliding grooves are formed in the periphery of the interior of the containing barrel, sliding blocks are slidably connected into the multiple sliding grooves, supporting seats are fixedly connected between the adjacent sliding blocks, and multiple connecting grooves are formed in the bottom of the inner side of the rotating table. According to the test tube separation device, the test tube is blocked through the blocking column, the iron column is attracted through the magnet, the test tube is fixed, after separation is completed, the top cover can be taken out, extrusion of the blocking column to the test tube is relieved, and meanwhile the test tube is ejected outwards under the action of the second spring and the supporting base; therefore, a plurality of test tubes can be quickly taken out.

Description

TECHNICAL FIELD

[0001] The utility model relates to centrifuge technical field especially, relates to a centrifuge for cell separation. BACKGROUND

[0002] Cells are the basic unit of life, widely exist in various organisms, in medical and biological research, cell separation and purification are the important experiment foundation of carrying out cell function research, disease diagnosis and treatment, traditional cell separation method includes centrifugal method, filtration method, density gradient centrifugation, these methods have respective advantages and disadvantages, centrifugal method is widely used because of simple operation, high separation efficiency.

[0003] Centrifuge is the mechanical separation of liquid and solid particles or liquid and liquid mixture in each component by centrifugal force, centrifuge is mainly used to separate solid particles and liquid in suspension, and the solid particles with different density or granularity in liquid have different sedimentation speed characteristics, and some sedimentation centrifuges can also classify solid particles according to density or granularity.

[0004] The existing centrifuge can place multiple test tubes in the installation groove and fix them, the centrifuge is started to realize the rapid separation of cells in the test tubes, the test tubes are mostly placed in the same size slot, so as to avoid the knocking during high-speed rotation, but after separation, the test tubes are difficult to be directly taken out, and need to be taken out by using specific taking-out device, so not only the test tubes are easy to be damaged, but also the taking is inconvenient, therefore, the centrifuge for cell separation is provided to solve the above problems. UTILITY MODEL CONTENT

[0005] In order to make up for the above shortcomings, the utility model provides a centrifuge for cell separation, which aims at improving the problem that the specific taking-out device is needed to take out in the prior art, so not only the test tubes are easy to be damaged, but also the taking is inconvenient.

[0006] In order to achieve the above object, the utility model discloses the following technical scheme: a centrifuge for cell separation, including case, test tube and sealing cover, the inner side bottom of case is fixedly connected with motor, the output of motor is fixedly connected with rotating table, the inner side all around of rotating table is connected with the placing cylinder, the inside all around of placing cylinder is equipped with the sliding slot, the inside all around of a plurality of sliding slots is slidably connected with the sliding block, the adjacent between a plurality of sliding blocks is fixedly connected with support seat, the inner side bottom of rotating table is equipped with a plurality of connecting grooves, the inside all around of a plurality of connecting grooves is slidably connected with the slide bar, the top of slide bar is fixedly connected in the bottom of support seat, the outer wall of slide bar is fixedly connected with spring no.

[0007] As a further description of the above technical solution:

[0008] The locking mechanism includes a limiting box, the bottom of the limiting box is fixedly connected to the top of the case, the left and right sides of the limiting box are slidably connected with clamping plates, the adjacent sides of the two clamping plates are fixedly connected with limiting rods, the outer walls of the two limiting rods are fixedly connected with springs, the front side of the sealing cover is provided with a plug-in slot, and the top front side of the sealing cover is provided with a clamping slot.

[0009] As a further description of the above technical solution:

[0010] The inner wall top of the placing cylinder is fixedly connected with a rubber ring, and the outer wall of the test tube is slidably connected to the inner wall of the rubber ring.

[0011] As a further description of the above technical solution:

[0012] The top rear side of the case is rotatably connected with a hinge, and the bottom rear side of the sealing cover is rotatably connected to the outer wall of the hinge.

[0013] As a further description of the above technical solution:

[0014] The top of the sealing cover is fixedly connected with a handle, and the outer wall of the handle is fixedly connected with an anti-skid sleeve.

[0015] As a further description of the above technical solution:

[0016] The left and right sides of the sealing cover are rotatably connected with hydraulic rods, and the other ends of the two hydraulic rods are rotatably connected to the left and right sides of the case.

[0017] As a further description of the above technical solutions:

[0018] The inner part of the case is fixedly connected with a slide, the outer wall of the rotating table is movably connected with a pulley around, and the top of the top cover is provided with a buckle groove around.

[0019] As a further description of the above technical solutions:

[0020] The front side of the case is fixedly connected with a control panel, and the front side of the case is fixedly connected with a switch.

[0021] The utility model has the advantages of the following:

[0022] 1、 the utility model discloses a test tube is inserted in the placement cylinder, and is supported to the test tube through the support seat, and the iron column of the top cover bottom is inserted into the jack, and the plugging column is inserted into the top of the test tube, and is sealed, and the iron column is adsorbed through the magnet, and the spring two is extruded, the fixing of the test tube is improved, when separating is completed, the top cover can be taken out, and the extrusion of the test tube is released through the plugging column, and the test tube is pushed out outward under the action of spring two and the support seat, so that multiple test tubes can be taken out quickly, and the utility model is more convenient to use.

[0023] 2、 the utility model discloses that the limiting box is quickly positioned and connected with the plug-in slot of the front side of the sealing cover, and is pressed in through the card, and the spring one is inwards retracted, and after the sealing cover is completely closed, the card plate is loosened, and the card plate is quickly clamped in the card slot under the action of the card plate, and the fixing treatment of the sealing cover is quickly completed, and the firmness and the sealing property of the sealing cover are improved. DRAWINGS

[0024] Figure 1 A perspective view of the centrifugal machine for cell separation is provided for the utility model;

[0025] Figure 2 A front view of the centrifugal machine for cell separation is provided for the utility model;

[0026] Figure 3 An explosion view of the centrifugal machine for cell separation is provided for the utility model;

[0027] Figure 4 A sectional view of the centrifugal machine for cell separation is provided for the utility model;

[0028] Figure 5 A disassembly view of the centrifugal machine for cell separation is provided for the utility model.

[0029] LEGEND:

[0030] 1, case; 2, locking mechanism; 201, limiting box; 202, clamping plate; 203, limiting rod; 204, spring one; 205, plug slot; 206, clamping groove; 3, motor; 4, rotating table; 5, placing cylinder; 6, sliding groove; 7, sliding block; 8, support seat; 9, sliding rod; 10, spring two; 11, connecting groove; 12, test tube; 13, rubber ring; 14, jack; 15, magnet; 16, plugging column; 17, iron column; 18, top cover; 19, buckle groove; 20, hinge; 21, sealing cover; 22, handle; 23, anti-skid sleeve; 24, hydraulic rod; 25, slide; 26, pulley; 27, control panel; 28, switch. DETAILED DESCRIPTION

[0031] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0032] Reference Figure 1 , Figure 3 and Figure 4The utility model provides an embodiment: a centrifuge for cell separation, including case 1, test tube 12 and sealing cover 21, the rear side of the top of case 1 is rotatably connected with hinge 20, the rear side of the bottom of sealing cover 21 is rotatably connected in the outer wall of hinge 20, and the case 1 is connected with sealing cover 21 through hinge 20, the sealing property of case 1 is ensured through sealing cover 21, the sound insulation is improved simultaneously and the liquid splashing condition is avoided, the inside bottom of case 1 is fixedly connected with motor 3, the output of motor 3 is fixedly connected with rotating table 4, and the inside four all of rotating table 4 are communicated with placing cylinder 5, and the high speed rotation of rotating table 4 is driven through starting motor 3, the quick separation of the cell in test tube 12 is realized, the inside four all of placing cylinder 5 are provided with sliding slot 6, the inside of multiple sliding slots 6 is slidably connected with sliding block 7, and the adjacent between multiple sliding blocks 7 is fixedly connected with support base 8, the inside bottom of rotating table 4 is provided with multiple connecting grooves 11, the inside of multiple connecting grooves 11 is slidably connected with slide rod 9, the top of slide rod 9 is fixedly connected in the bottom of support base 8, the outer wall of slide rod 9 is fixedly connected with spring no.

[0033] Specifically, the sealing cover 21 is fixed on the hinge 20 through the rotation connection at the bottom rear side, so as to realize the close connection between the case 1 and the sealing cover 21. This design not only ensures the sealing of the case 1, effectively prevents the noise generated in the centrifugal process from leaking out, but also avoids the risk of liquid splashing, guarantees the safety and cleanliness of the experimental environment, and the inner bottom of the case 1 is fixedly installed with a motor 3 as a core component of driving force. The output end of the motor 3 is directly connected to a rotating table 4 located at the center position of the case 1. A plurality of placing cylinders 5 are evenly distributed around the inner side of the rotating table 4. These placing cylinders 5 are specially designed for test tubes 12 to ensure that each test tube can be stably placed. After starting the motor 3, the rotating table 4 will rotate at high speed, and the cells in the test tubes 12 are quickly separated by using the principle of centrifugal force. In order to further improve the stability of the test tubes 12 in the high-speed rotating process, grooves 6 are carefully designed around the inner side of the placing cylinders 5, and sliding blocks 7 are slidably connected in the grooves. The sliding blocks 7 are connected to each other through support seats 8, forming a stable support structure, which effectively prevents the test tubes 12 from deviating or toppling during rotation. In addition, a plurality of connecting grooves 11 are formed in the inner bottom of the rotating table 4, and a sliding rod 9 is slidably connected in each connecting groove. The top end of the sliding rod 9 is fixedly connected to the bottom of the support seat 8, and the outer wall is fixedly connected with a spring 10. These springs not only provide additional support, but also assist the test tubes in smoothly popping out when the test tubes are taken out. In terms of test tube placement and fixation, the test tubes 12 are inserted into the placing cylinders 5 and supported by the support seats 8. At this time, the iron column 17 at the bottom of the top cover 18 is inserted into the insertion hole 14 at the top of the rotating table 4. The insertion hole 14 is fixedly provided with a magnet 15 at the inner bottom, which can attract the iron column 17 and press the spring 10, thereby enhancing the fixation effect of the test tubes 12. At the same time, the plugging column 16 is inserted into the top of the test tube 12 for plugging to prevent liquid from splashing out during the centrifugal process. When the cell separation is completed, the user only needs to take out the top cover 18 to release the fixation and plugging of the test tubes 12. At this time, the test tubes 12 will automatically pop out outward under the joint action of the spring 10 and the support seat 8, so that the user can quickly take out multiple test tubes for operation, greatly improving the experimental efficiency. At the same time, the inner wall top of the placing cylinder 5 is fixedly connected with a rubber ring 13, and the outer wall of the test tube 12 is slidably connected in the inner wall of the rubber ring 13 to provide additional buffer and protection, avoiding the test tubes from being damaged by collision during high-speed rotation. The inner wall of the case 1 is also fixedly provided with a sliding channel 25, and the outer wall of the rotating table 4 is rotatably connected with a pulley 26. These designs make the rotating table rotate more smoothly, and the top cover 18 is also provided with a buckle groove 19 at the top for user operation and locking.

[0034] Referring to Figure 1 , Figure 2 and Figure 5The locking mechanism 2 comprises a limiting box 201, the bottom of the limiting box 201 is fixedly connected to the top front side of the cabinet 1, the left and right sides of the limiting box 201 are slidably connected with clamping plates 202, the adjacent sides of the two clamping plates 202 are fixedly connected with limiting rods 203, the outer walls of the two limiting rods 203 are fixedly connected with springs 204, the front side of the sealing cover 21 is provided with a plug-in slot 205, the top front side of the sealing cover 21 is provided with a clamping groove 206, the limiting box 201 is quickly positioned and connected with the plug-in slot 205 on the front side of the sealing cover 21, the clamping plates 202 are pressed inward, the springs 204 are retracted inward, after the sealing cover 21 is completely closed, the clamping plates 202 are released, the clamping plates 202 are quickly clamped in the clamping groove 206 under the action of the clamping plates 202, the fixing of the sealing cover 21 is quickly completed, and the firmness and sealing performance of the sealing cover 21 are improved;

[0035] Specifically, the limiting box 201 is fixed on the top front side of the cabinet 1, the stability and accuracy are ensured, the left and right sides of the limiting box 201 are respectively designed with a sliding connection structure, so that the two clamping plates 202 can smoothly slide along the sliding connection structure, the two clamping plates 202 play a locking role, the adjacent sides of the two clamping plates 202 are respectively fixedly connected with a limiting rod 203, the limiting rods 203 not only provide stable support for the clamping plates 202, but also serve as the fixed points of the springs 204, the springs 204 are directly fixedly connected to the outer walls of the limiting rods 203, which provide necessary elasticity and reset ability in the locking process, on the other hand, the front side of the sealing cover 21 is designed with a plug-in slot 205, the plug-in slot 205 is matched with the shape and size of the limiting box 201, so as to realize quick positioning and connection; meanwhile, the top front side of the sealing cover 21 is also provided with a clamping groove 206, which is used for cooperating with the clamping plates 202 to complete locking, in the operation process, firstly, the sealing cover 21 is quickly positioned and connected with the limiting box 201 through the plug-in slot 205; then, the two clamping plates 202 are pressed inward, so that the springs 204 are retracted inward, thereby providing space for further closing of the sealing cover 21, when the sealing cover 21 is completely closed, the clamping plates 202 are released, at this time, under the elastic force of the springs 204, the clamping plates 202 will quickly pop out and be clamped in the clamping groove 206 of the sealing cover 21, this process realizes quick and firm fixing of the sealing cover 21, and significantly improves the sealing performance and stability.

[0036] Referring to Figure 1 , Figure 2 and Figure 5The top of the sealing cover 21 is fixedly connected with a handle 22, the outer wall of the handle 22 is fixedly connected with an anti-skid sleeve 23, the left and right sides of the sealing cover 21 are rotatably connected with hydraulic rods 24, the other ends of the two hydraulic rods 24 are rotatably connected to the left and right sides of the cabinet 1, the front side of the cabinet 1 is fixedly connected with a control panel 27, and the front side of the cabinet 1 is fixedly connected with a switch 28.

[0037] Specifically, the top of the sealing cover 21 is provided with a handle 22 in a fixed connection mode, and an anti-skid sleeve 23 is fixedly connected to the outer wall of the handle 22 to ensure that the user can operate more stably and comfortably. The left and right sides of the sealing cover 21 are respectively provided with two hydraulic rods 24 in a rotatable connection mode, and the other ends of the two hydraulic rods 24 are respectively rotatably connected to the left and right sides of the cabinet 1. The front side of the cabinet 1 is fixedly connected with a control panel 27, which can facilitate the user to operate and set various operations. In addition, the front side of the cabinet 1 is also fixedly connected with a switch 28, which can be used to control the power supply or other functions of the cabinet.

[0038] Working principle: first, the sealing cover 21 ensures the sealing of the cabinet 1, improves the sound insulation, and avoids the splashing of liquid. The motor 3 is started to drive the rotating table 4 to rotate at high speed, realizing the rapid separation of the cells in the test tube 12. The test tube 12 is inserted into the placement cylinder 5, and the test tube 12 is supported by the support seat 8. The iron column 17 at the bottom of the top cover 18 is inserted into the insertion hole 14, and the blocking column 16 is inserted into the top of the test tube 12 to block it. The magnet 15 is used to adsorb the iron column 17 to extrude the spring 10, thereby improving the fixation of the test tube 12. When the separation is completed, the top cover 18 can be removed, the blocking column 16 is released from the extrusion of the test tube 12, and the test tube 12 is pushed out under the action of the spring 10 and the support seat 8. In this way, multiple test tubes 12 can be quickly removed, and the use is more convenient.

[0039] And the limiting box 201 is quickly positioned and connected with the insertion slot 205 on the front side of the sealing cover 21, and the spring 204 is retracted inward by pressing the clamping plate 202 inward. After the sealing cover 21 is completely closed, the clamping plate 202 is released, and the clamping plate 202 is quickly clamped in the clamping groove 206 under the action of the clamping plate 202, so that the fixation of the sealing cover 21 is quickly completed, and the firmness and sealing performance of the sealing cover 21 are improved.

[0040] Finally, it should be noted that: the above only for the preferred embodiments of the present application, and is not intended to limit the present application, although the foregoing embodiments of the present application has been described in detail, for the skilled in the art, it still can be modified, or for part of the technical features of the equivalent replacement, the spirit and principles of the present application, the made any modification, equivalent replacement, improvement, etc., should be included within the scope of the present application.

Claims

1. A centrifuge for cell separation, comprising a casing (1), a test tube (12) and a seal cover (21), characterized in that: The inner side bottom of the case (1) is fixedly connected with a motor (3), the output end of the motor (3) is fixedly connected with a rotating table (4), the inner side four around of the rotating table (4) are communicated with a placing cylinder (5), the inside four around of the placing cylinder (5) are provided with a sliding groove (6), the inside of multiple sliding grooves (6) are slidably connected with a sliding block (7), the adjacent between multiple sliding blocks (7) are fixedly connected with a support seat (8), the inner side bottom of the rotating table (4) is provided with multiple connecting grooves (11), the inside of multiple connecting grooves (11) are slidably connected with a sliding rod (9), the top end of the sliding rod (9) is fixedly connected with the bottom of the support seat (8), the outer wall of the sliding rod (9) is fixedly connected with spring two (10), the top of multiple placing cylinders (5) are slidably connected with a blocking column (16), the top end of multiple blocking columns (16) are fixedly connected with a top cover (18), the bottom four around of the top cover (18) are fixedly connected with an iron column (17), the top four around of the rotating table (4) are provided with a jack (14), the inner side bottom of multiple jacks (14) are fixedly connected with a magnet (15), the top of the case (1) is provided with a locking mechanism (2), the locking mechanism (2) is used for strengthening the sealing property of the sealing cover (21).

2. A centrifuge for cell separation according to claim 1, characterized in that: The locking mechanism (2) comprises a limiting box (201), the bottom of the limiting box (201) is fixedly connected with the top of the case (1) on the front side, the left and right sides of the limiting box (201) are slidably connected with a clamping plate (202), the adjacent side of two clamping plates (202) is fixedly connected with a limiting rod (203), the outer wall of two limiting rods (203) is fixedly connected with spring one (204), the front side of the sealing cover (21) is provided with a plug-in groove (205), the top front side of the sealing cover (21) is provided with a clamping groove (206).

3. The cell separation centrifuge according to claim 1, characterized in that: The inner wall top end of the placing cylinder (5) is fixedly connected with a rubber ring (13), the outer wall of the test tube (12) is slidably connected with the inner wall of the rubber ring (13).

4. The cell separation centrifuge according to claim 1, characterized in that: The top rear side of the case (1) is rotatably connected with a hinge (20), the bottom rear side of the sealing cover (21) is rotatably connected with the outer wall of the hinge (20).

5. The cell separation centrifuge according to claim 1, characterized in that: The top of the sealing cover (21) is fixedly connected with a handle (22), the outer wall of the handle (22) is fixedly connected with an anti-skid sleeve (23).

6. The cell separation centrifuge according to claim 1, characterized in that: The left and right sides of the sealing cover (21) are rotatably connected with a hydraulic rod (24), the other end of two hydraulic rods (24) is rotatably connected with the left and right sides of the case (1).

7. The centrifuge for cell separation according to claim 1, characterized in that: The inside of the case (1) is fixedly connected with a sliding way (25), the outer wall four around of the rotating table (4) are rotatably connected with a pulley (26), the top four around of the top cover (18) are provided with a buckling groove (19).

8. The centrifuge for cell separation according to claim 1, characterized in that: The front side of the case (1) is fixedly connected with a control panel (27), the front side of the case (1) is fixedly connected with a switch (28).

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