Platelet-enriched plasma separation device

Abstract

The utility model relates to the technical field of blood separation, and discloses a platelet-enriched plasma separation device which comprises a workbench, a support is fixedly connected to the rear side of the top of the workbench, a separator is fixedly connected to the top of the support, and the output end of the separator penetrates through the support and is fixedly connected with a rotating rod. A fixing disc is slidably connected to the outer wall of the rotating rod, fixing bolts are rotatably connected to the left side and the right side of the fixing disc, centrifugal pipes are slidably connected to the interiors of the fixing bolts, a plurality of first filtering holes are formed in the top of the outer wall of each centrifugal pipe at equal intervals, and a plurality of second filtering holes are formed in the upper middle portion of the outer wall of each centrifugal pipe at equal intervals; a collecting pipe I is fixedly connected to the middle upper part of the outer wall of the centrifugal pipe. According to the device, a blood sample is layered in the centrifugal tube by virtue of centrifugal force, different components are separated by virtue of the filter holes I and the filter holes II in the outer wall of the centrifugal tube, and platelet-enriched plasma is efficiently separated by virtue of multi-layer separation.

Description

TECHNICAL FIELD

[0001] The utility model relates to blood separation technical field especially, relate to a kind of platelet-rich plasma separation device. BACKGROUND

[0002] Plasma is an important component of blood, a pale yellow liquid, containing water, protein and electrolytes, plasma plays a very key role in the human body, as a transport carrier, responsible for the transport of nutrients to the various tissues and organs of the body, while the waste produced by cell metabolism is transported to the excretory organs to be excreted from the body, in addition, various proteins in plasma such as albumin, globulin and fibrinogen participate in maintaining the osmotic pressure of blood, acid-base balance and immune defense physiological function, in the medical field, the application of plasma is very wide, plasma can be used to supplement the blood components reduced due to blood loss, correct coagulation dysfunction, platelets play an important role in the process of coagulation, medical professionals separate platelets from plasma and use platelets alone, so platelet separation device is needed.

[0003] Platelet separation device is a medical device specially used for extracting platelets from whole blood, its main working principle is to separate platelets from red blood cells, white blood cells and plasma components through specific centrifugation program and separation medium according to the density difference of each component in blood and the action of centrifugal force, platelets play a core role in the process of hemostasis and coagulation in the human body, can quickly adhere and aggregate and release bioactive substances when blood vessels are damaged, forming platelet thrombus, thereby preventing further bleeding, the application of platelet separation device has important significance for the treatment and prevention of many diseases.

[0004] The platelet separation device on the market at present is to put whole blood into a centrifuge tube and then rotate the centrifuge tube at high speed to separate the whole blood, when the centrifuge tube is rotated at high speed, because the whole blood is put into a centrifuge tube, the separated liquid is stratified in the centrifuge tube, and other liquids are easily mixed during extraction, resulting in impure separation, the prior art is to separate the separated liquid again to improve the purity of platelets, but multiple separation operations increase the risk of platelet damage, thereby affecting the hemostatic and tissue repair functions of platelets, and multiple separation during surgery also increases the separation time, which may cause delay of surgical procedure. UTILITY MODEL CONTENTS

[0005] In order to make up for the above shortcomings, the utility model provides a platelet-rich plasma separation device, which aims to improve the problem that multiple separation operations in the prior art increase the risk of platelet damage, thereby affecting the hemostatic and tissue repair functions of platelets.

[0006] In order to achieve the above object, the utility model discloses the following technical scheme: a kind of platelet-rich plasma separation device, including workbench, the top rear side of the workbench is fixedly connected with support, the top of the support is fixedly connected with separator, the output end of the separator is through support and is fixedly connected with rotating rod, the outer wall of the rotating rod is slidably connected with fixed disc, the left and right sides of the fixed disc are rotatably connected with fixed bolt, the inside of the fixed bolt is slidably connected with centrifuge tube, a plurality of filter holes one are equidistantly arranged on the top of the outer wall of the centrifuge tube, a plurality of filter holes two are equidistantly arranged on the middle upper portion of the outer wall of the centrifuge tube, the outer wall of the centrifuge tube is fixedly connected with collection tube one in middle upper portion, the outer wall of the centrifuge tube is fixedly connected with collection tube two in top, the top of the workbench is provided with circular groove, the outer wall of the collection tube two is rotatably connected in the inside of circular groove, the left and right sides of the top of the workbench are provided with support mechanism, and the support mechanism is used to support collection tube two.

[0007] As further description of the above technical solution:

[0008] The support mechanism includes annular groove, the outer wall of the collection tube two is provided with annular groove, the inside of the annular groove is slidably connected with annular ring, the top of the workbench is fixedly connected with stand on the left and right sides, the front and back sides of two stands are provided with sliding slot, the inside of multiple sliding slots is fixedly connected with spring on one side, one end of multiple springs is fixedly connected with corresponding sliding plate, one side of multiple sliding plates is rotatably connected with connecting plate, the other end of multiple connecting plates is rotatably connected with fixed plate, and one side of multiple fixed plates is slidably connected on the outer wall of annular ring.

[0009] As further description of the above technical solution:

[0010] The bottom of the collection tube two is fixedly connected with swivel, and the inside of the circular groove is fixedly connected with cylinder.

[0011] As further description of the above technical solution:

[0012] The top front side of the workbench is fixedly connected with switch, and the switch is electrically connected with separator.

[0013] As further description of the above technical solution:

[0014] The left and right sides of the support are fixedly connected with triangular plate, and the bottom of two triangular plates is fixedly connected on the top of the workbench.

[0015] As further description of the above technical solution:

[0016] The bottom of the workbench is fixedly connected with support frame, and the bottom of the support frame is fixedly connected with bottom plate.

[0017] As a further description of the above technical solutions:

[0018] The upper and lower sides of the plurality of sliding grooves are provided with sliding grooves, and the upper and lower sides of the plurality of sliding plates are fixedly connected with sliding blocks, and the plurality of sliding blocks are slidably connected with the interiors of the corresponding sliding grooves.

[0019] As a further description of the above technical solutions:

[0020] The left and right sides of the rotating rod are fixedly connected with limiting blocks, and the left and right sides of the interior of the fixed disc are provided with limiting grooves.

[0021] The utility model has the advantages of the following beneficial effects:

[0022] 1. In the utility model, the separator drives the rotating rod to rotate at high speed, so that the fixed disc and the centrifugal tube connected with the rotating rod perform high-speed centrifugal motion, the blood sample is stratified in the centrifugal tube by using the centrifugal force, different components are separated by the filter holes one and two on the outer wall of the centrifugal tube, and the lighter components such as plasma enter the collecting tube two and the collecting tube one respectively, and the rotating connection of the centrifugal tube and the circular groove guarantees the stability, and the efficient separation of platelet-rich plasma is realized through multi-layer separation.

[0023] 2. In the utility model, the relative sliding cooperation of the ring and the ring groove provides a movable base for the related components of the stand and the internal sliding groove, the spring exerts an initial force on the sliding plate, when the collecting tube two shakes and drives the fixed plate to move, the sliding plate moves against the spring elastic force, then the spring pulls it back, the connecting plate and the fixed plate exert a reverse force on the ring, the amplitude of the shaking of the collecting tube two is reduced, and the stable and continuous work is carried out. DRAWINGS

[0024] Figure 1 A perspective view of a platelet-rich plasma separation device is provided for the utility model;

[0025] Figure 2 A structural cross-sectional view of a platelet-rich plasma separation device is provided for the utility model;

[0026] Figure 3 A support mechanism structure schematic view of a platelet-rich plasma separation device is provided for the utility model;

[0027] Figure 4 A structural top view of a platelet-rich plasma separation device is provided for the utility model;

[0028] Figure 5 A Figure 4 enlarged view of A in the utility model.

[0029] Legend:

[0030] 1, workbench; 2, support mechanism; 201, ring groove; 202, circular ring; 203, column; 204, sliding groove; 205, spring; 206, sliding plate; 207, connecting plate; 208, fixed plate; 3, support; 4, separator; 5, rotating rod; 6, fixed disc; 7, fixed bolt; 8, centrifugal tube; 9, filter hole one; 10, filter hole two; 11, collection tube one; 12, collection tube two; 13, circular groove; 14, rotating ring; 15, switch; 16, triangular plate; 17, support frame; 18, bottom plate; 19, sliding groove; 20, sliding block; 21, limiting block; 22, limiting groove; 23, cylinder. DETAILED DESCRIPTION

[0031] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0032] Reference Figure 1 , Figure 2 and Figure 4The utility model provides an embodiment: a kind of platelet-rich plasma separation device, including workbench 1, workbench 1 can provide the installation basis and working plane of entire device, its top rear side is fixedly connected with support 3, support 3 is used to support and fix other components, the top of support 3 is fixedly connected with separator 4, separator 4 can generate power to promote centrifugal separation action to carry out, the output end of separator 4 penetrates support 3 and is fixedly connected with rotating rod 5, rotating rod 5 can rotate and transmit power under the driving of separator 4, the outer wall of rotating rod 5 is slidably connected with fixed disc 6, fixed disc 6 is convenient for adjusting position and fixed centrifuge tube 8, the left and right sides of fixed disc 6 are all connected with fixed bolt 7, fixed bolt 7 is used to fasten centrifuge tube 8, the inside of fixed bolt 7 is slidably connected with centrifuge tube 8, centrifuge tube 8 is the container that accommodates blood sample and carries out centrifugal separation operation, multiple filter holes one 9 are equidistantly opened in the top of the outer wall of centrifuge tube 8, filter hole one 9 can make partial plasma component preliminary separation, multiple filter holes two 10 are equidistantly opened in the middle upper portion of the outer wall of centrifuge tube 8, filter hole two 10 can further separate different plasma components, the outer wall of centrifuge tube 8 is fixedly connected with collecting tube one 11 in middle upper portion, collecting tube one 11 is used to collect specific plasma component, the top of the outer wall of centrifuge tube 8 is fixedly connected with collecting tube two 12, collecting tube two 12 can collect another part of separated plasma, the top of workbench 1 is provided with circular groove 13, circular groove 13 provides space and guide for the rotation of collecting tube two 12, the outer wall of collecting tube two 12 is rotatably connected in the inside of circular groove 13, guarantee the stable rotation of collecting tube two 12 in centrifugal process, the top of workbench 1 is provided with support mechanism 2 on left and right sides, support mechanism 2 is used to support collecting tube two 12, enhances the stability of collecting tube two 12, the bottom of collecting tube two 12 is fixedly connected with swivel 14, swivel 14 is convenient for relative rotation of collecting tube two 12, the inside of circular groove 13 is fixedly connected with cylinder 23, cylinder 23 and swivel 14 cooperate to realize the function of rotation connection.

[0033] Referring to Figure 2 and Figure 3The support mechanism 2 comprises a ring groove 201, the outer wall of the collecting pipe two 12 is provided with the ring groove 201, the ring groove 201 can be used as the structural basis connected and matched with other components, the inner side of the ring groove 201 is slidably connected with a circular ring 202, the circular ring 202 can be flexibly moved in the ring groove 201 to adapt to different states, the top left and right sides of the workbench 1 are fixedly connected with a stand column 203, the stand column 203 plays a supporting and bearing role of other parts, the front and back sides of the two stand columns 203 are provided with sliding grooves 204, the sliding grooves 204 provide a guide path for the sliding of other parts, the inner side of the plurality of sliding grooves 204 is fixedly connected with springs 205, the springs 205 can store and release elastic potential energy to realize the buffering and resetting functions, one end of the plurality of springs 205 is fixedly connected with corresponding sliding plates 206, the sliding plates 206 can slide in the sliding grooves 204 under the action of the springs 205, one side of the plurality of sliding plates 206 is rotatably connected with connecting plates 207, the connecting plates 207 can change the transmission direction of force and realize the relative rotation between connected components, the other end of the plurality of connecting plates 207 is rotatably connected with fixed plates 208, the fixed plates 208 can play a fixing and supporting role in the connection with the circular ring 202, one side of the plurality of fixed plates 208 is slidably connected to the outer wall of the circular ring 202, so that the circular ring 202 can stably move under the constraint of the plurality of fixed plates 208, the upper and lower sides of the plurality of sliding grooves 204 are provided with sliding grooves 19, the sliding grooves 19 provide more accurate guidance for the sliding of other parts, the upper and lower sides of the plurality of sliding plates 206 are fixedly connected with sliding blocks 20, the sliding blocks 20 can smoothly slide in the sliding grooves 19 to reduce friction and ensure the accuracy of the sliding direction, the plurality of sliding blocks 20 are slidably connected with the interiors of the corresponding sliding grooves 19, to guarantee the coordination and stability of the movement of all components of the support mechanism 2.

[0034] With reference to Figure 1 and Figure 5The top front side of the workbench 1 is fixedly connected with a switch 15, which can be used as a control component of the whole device, facilitating the user to operate the start and stop of the equipment. The switch 15 is electrically connected with the separator 4, so as to realize effective control of the working state of the separator 4. The left and right sides of the support 3 are fixedly connected with triangular plates 16, which can enhance the stability of the support 3 and prevent it from shaking or tilting. The bottoms of the two triangular plates 16 are fixedly connected to the top of the workbench 1, so that the triangular plates 16 can better play a stable supporting role. The bottom of the workbench 1 is fixedly connected with a support frame 17, which provides a solid support structure for the workbench 1 and ensures the stable placement of the whole device. The bottom of the support frame 17 is fixedly connected with a bottom plate 18, which increases the contact area with the ground and further improves the stability of the device. The left and right sides of the rotating rod 5 are fixedly connected with limiting blocks 21, which can limit the sliding range of the fixed disc 6 on the rotating rod 5 and prevent it from coming out. The left and right sides of the inside of the fixed disc 6 are provided with limiting grooves 22, which cooperate with the limiting blocks 21 to accurately determine the position of the fixed disc 6 on the rotating rod 5 and ensure its stable rotation.

[0035] Working principle: when using the platelet-rich plasma separation device, when starting the device, the separator 4 starts to work and drives the rotating rod 5 to rotate at high speed. When the rotating rod 5 rotates, the fixed disc 6 connected with it also rotates. The fixed disc 6 drives the centrifugal tube 8 to move at high speed through the fixed bolts 7 on the left and right sides. During the centrifugal process, the blood sample is placed in the centrifugal tube 8. Due to the centrifugal force, different components in the blood begin to separate. Among them, the filter hole one 9 at the top of the outer wall of the centrifugal tube 8 and the filter hole two 10 at the middle and upper part play a key role in separation. Larger particles such as red blood cells are blocked inside the centrifugal tube 8 under the action of centrifugal force, while lighter components such as plasma can pass through the filter hole one 9 and the filter hole two 10 into the collection tube two 12 and the collection tube one 11 respectively. The collection tube two 12 is used to collect the preliminarily separated plasma components, and the collection tube one 11 collects the specific plasma components after further separation. The centrifugal tube 8 is connected in the circular groove 13 at the top of the workbench 1 during rotation. This connection mode ensures the stability of the centrifugal tube 8 during high-speed rotation, preventing it from shaking or deviating, thereby ensuring the accuracy and efficiency of the entire separation process. When the collection tube two 12 is in working condition, the circular ring 202 can slide in the ring groove 201. The sliding grooves 204 on the front and back sides of the stand 203 provide a moving space for the sliding plate 206. The spring 205 is initially in a certain compression or stretching state, giving the sliding plate 206 an inward force. When the collection tube two 12 is disturbed by external force or slightly shakes during operation, the shaking will be transmitted to the circular ring 202. The movement of the circular ring 202 will drive the fixed plate 208 connected with it to move. Since the fixed plate 208 is rotationally connected with the sliding plate 206 through the connecting plate 207, when the fixed plate 208 moves, it will make the sliding plate 206 move in the sliding groove 204 against the elastic force of the spring 205. The elastic force of the spring 205 will quickly pull the sliding plate 206 back to the initial position after the collection tube two 12 shakes, and then apply a reverse force to the circular ring 202 through the connecting plate 207 and the fixed plate 208, so that the collection tube two 12 returns to a stable state, thereby effectively reducing the shaking amplitude of the collection tube two 12 and ensuring that the plasma separation work of the collection tube two 12 and related components can be stable and continuous during the operation of the device.

[0036] Finally, it should be pointed out that the above description is only a preferred embodiment of the present application and is not intended to limit the present application. Although the present application has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent replacements to some technical features, as long as they are within the spirit and principles of the present application. Any modification, equivalent replacement, improvement, etc. made within the scope of the present application shall be included in the protection scope of the present application.

Claims

1. An enriched platelet plasma separation device comprising a worktable (1), characterized in that: The top rear side of the workbench (1) is fixedly connected with a support (3), the top of the support (3) is fixedly connected with a separator (4), the output end of the separator (4) penetrates through the support (3) and is fixedly connected with a rotating rod (5), the outer wall of the rotating rod (5) is slidably connected with a fixed disc (6), the left and right sides of the fixed disc (6) are rotatably connected with fixed bolts (7), the inside of the fixed bolt (7) is slidably connected with a centrifugal tube (8), a plurality of filter holes one (9) are equidistantly arranged on the top of the outer wall of the centrifugal tube (8), a plurality of filter holes two (10) are equidistantly arranged on the middle upper portion of the outer wall of the centrifugal tube (8), the outer wall of the middle upper portion of the centrifugal tube (8) is fixedly connected with a collection tube one (11), the top of the outer wall of the centrifugal tube (8) is fixedly connected with a collection tube two (12), the top of the workbench (1) is provided with a circular groove (13), the middle lower portion of the outer wall of the collection tube two (12) is rotatably connected inside the circular groove (13), the left and right sides of the top of the workbench (1) are provided with support mechanisms (2), and the support mechanisms (2) are used for supporting the collection tube two (12).

2. The platelet rich plasma separation device of claim 1, wherein: The support mechanism (2) comprises a ring groove (201), the outer wall of the collection tube two (12) is provided with a ring groove (201), the inside of the ring groove (201) is slidably connected with a circular ring (202), the top of the workbench (1) is fixedly connected with a stand column (203) on the left and right sides, the front and rear sides of the two stand columns (203) are provided with sliding grooves (204), the inside of the plurality of sliding grooves (204) is fixedly connected with springs (205) on one side, one end of the plurality of springs (205) is fixedly connected with corresponding sliding plates (206), one side of the plurality of sliding plates (206) is rotatably connected with connecting plates (207), the other end of the plurality of connecting plates (207) is rotatably connected with fixed plates (208), and one side of the plurality of fixed plates (208) is slidably connected to the outer wall of the circular ring (202).

3. The platelet rich plasma separation device of claim 1, wherein: The bottom of the collection tube two (12) is fixedly connected with a rotating ring (14), the inside of the circular groove (13) is fixedly connected with a circular column (23), and the bottom of the rotating ring (14) is rotatably connected with the top of the circular column (23).

4. The platelet rich plasma separation device of claim 1, wherein: The top front side of the workbench (1) is fixedly connected with a switch (15), and the switch (15) is electrically connected with the separator (4).

5. The platelet rich plasma separation device of claim 1, wherein: The left and right sides of the support (3) are fixedly connected with triangular plates (16), and the bottoms of the two triangular plates (16) are fixedly connected to the top of the workbench (1).

6. The platelet rich plasma separation device of claim 1, wherein: The bottom of the workbench (1) is fixedly connected with a support frame (17), and the bottom of the support frame (17) is fixedly connected with a bottom plate (18).

7. The platelet rich plasma separation device of claim 2, wherein: The upper and lower sides of the plurality of sliding grooves (204) are provided with sliding grooves (19), the upper and lower sides of the plurality of sliding plates (206) are fixedly connected with sliding blocks (20), and the plurality of sliding blocks (20) are respectively slidably connected with the inside of the corresponding sliding grooves (19).

8. The platelet rich plasma separation device of claim 1, wherein: The left and right sides of the rotating rod (5) are fixedly connected with limiting blocks (21), and the inner left and right sides of the fixed disc (6) are provided with limiting grooves (22).

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