Centrifugal tube for cell precipitation
By designing the centrifuge tube structure with a rotating block, shaft, inner shaft, and inner strips, the problem of cell fluid adhering to the inner wall of the tube was solved, achieving better centrifugation and sedimentation results.
Patent Information
- Application Number
- CN202520016550.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-01-06
- Publication Date
- 2025-12-30
- Estimated Expiration
- 2035-01-06
AI Technical Summary
In existing centrifuge tubes, cell fluid components tend to adhere to the inner wall of the tube during the cell fluid precipitation process, resulting in poor centrifugation precipitation effect.
A centrifuge tube structure including a rotating block, a rotating shaft, an inner shaft, and an inner strip was designed. The rotating block drives the rotating shaft and the inner shaft to rotate, scraping off the cell fluid on the inner wall of the tube. The rubber sealing sleeve and ball bearings reduce frictional resistance. The inner shaft is kept in the correct position by the support sleeve to prevent sample liquid from entering the through hole.
It effectively scrapes away the cell fluid adhering to the inner wall of the tube, ensuring that the cell fluid can be completely precipitated during high-speed centrifugation and improving the centrifugation effect.
Smart Images
Figure CN223732809U_ABST
Abstract
Description
Technical Field
[0001] This utility model belongs to the field of centrifuge tube technology, specifically relating to a centrifuge tube for cell precipitation. Background Technology
[0002] Centrifuge tubes all have caps, which are used to prevent sample leakage, especially important when using radioactive or highly corrosive samples. The caps also prevent sample evaporation and support the centrifuge tubes, preventing deformation. When selecting a centrifuge tube, it's crucial to check for a tight seal to ensure it doesn't leak when inverted. The cell solution is then placed in the tube and centrifuged at high speed to precipitate the cells.
[0003] The existing centrifuge tubes have the following defects when used for cell precipitation: (1) First, the tube cap is removed, the collected cell fluid is put into the tube body, and then it is put into the centrifuge for processing. However, when the cell fluid is put into the tube, some cell fluid components will adhere to the inner wall of the tube, making it difficult to scrape off and thus unable to generate centrifugal force to precipitate under centrifugal motion. Therefore, we propose a centrifuge tube for cell precipitation. Utility Model Content
[0004] The purpose of this invention is to provide a centrifuge tube for cell precipitation, thereby solving the problem mentioned in the background art that centrifuge tubes cannot scrape off the cell fluid components adhering to the inner wall of the tube, thus affecting the centrifugation precipitation effect.
[0005] To achieve the above objectives, this utility model provides the following technical solution: a centrifuge tube for cell precipitation, comprising a centrifuge tube body, a tube cap connected to the top of the centrifuge tube body by a thread, an inner strip provided inside the centrifuge tube body, one side surface of the inner strip being in contact with the inner wall of the centrifuge tube body, an inner shaft connected to the other side of the inner strip, a rotating shaft being rotatably embedded in the tube cap, a rotating block being fixed to the top of the rotating shaft, and the top end of the inner shaft being fixed to the bottom surface of the rotating shaft.
[0006] Preferably, the outer wall of the rotating shaft is fitted with a rubber sealing sleeve, and the outer wall of the rubber sealing sleeve is fixed to the tube cover.
[0007] Preferably, the cross-section of the rotating shaft is circular, and the longitudinal section of the rotating shaft is I-shaped.
[0008] Preferably, the inner surface of the rotating shaft is provided with a spherical groove, and a ball bearing is embedded in the spherical groove.
[0009] Preferably, a support sleeve is fitted on the outer wall of the bottom end of the inner shaft, and the support sleeve is fixed to the inner end face of the centrifuge tube.
[0010] Preferably, the support sleeve has a circular cross-section and a through hole at its bottom end.
[0011] Preferably, the cross-section of the rotating block is circular, and the outer wall of the rotating block is fitted with an anti-slip sleeve.
[0012] Compared with the prior art, the beneficial effects of this utility model are:
[0013] (1) By using the designed rotating block, rotating shaft, inner shaft and inner strip, hold the rotating block and rotate the rotating shaft. The rotating shaft drives the inner strip on the inner shaft to rotate together. The inner strip scrapes off the cell liquid adhering to the inner wall of the centrifuge tube, so as to avoid the cell liquid adhering to the inner wall of the tube and not being able to centrifuge at high speed in the liquid, which would affect its precipitation. The designed rubber sealing sleeve is set on the outer wall of the rotating shaft and inside the tube cap to seal the gap between the two. The designed ball bearing reduces the frictional resistance between the rotating shaft surface and the tube cap surface. The designed support sleeve straightens the inner shaft and prevents the inner shaft from tilting. The designed through hole is opened at the bottom of the support sleeve to prevent the sample liquid from entering the support sleeve and preventing centrifugation. Attached Figure Description
[0014] Figure 1 This is a schematic diagram of the structure of this utility model;
[0015] Figure 2 This utility model Figure 1 Enlarged view of point A in the image;
[0016] Figure 3 This utility model Figure 1 Enlarged view of point B in the image;
[0017] Figure 4 This is a perspective view of the support sleeve of this utility model;
[0018] Figure 5 This is a perspective view of the assembly of the rotating block and the rotating shaft of this utility model;
[0019] In the diagram: 1. Centrifuge tube body; 2. Tube cap; 3. Anti-slip sleeve; 4. Rotary block; 5. Inner strip; 6. Inner shaft; 7. Ball bearing; 8. Rotating shaft; 9. Rubber sealing sleeve; 10. Through hole; 11. Support sleeve. Detailed Implementation
[0020] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0021] Example
[0022] Please see Figures 1 to 5 This utility model provides a technical solution: a centrifuge tube for cell precipitation, including a centrifuge tube body 1, a tube cap 2 connected to the top of the centrifuge tube body 1 by a thread, an inner strip 5 provided inside the centrifuge tube body 1, one side surface of the inner strip 5 adhering to the inner wall of the centrifuge tube body 1, and an inner shaft 6 connected to the other side of the inner strip 5, a rotating shaft 8 being rotatably embedded on the tube cap 2, and a rotating block 4 fixed to the top of the rotating shaft 8. By using the designed rotating block 4, rotating shaft 8, inner shaft 6 and inner strip 5, the rotating block 4 is held to rotate the rotating shaft 8, and the rotating shaft 8 drives the inner strip 5 on the inner shaft 6 to rotate together. The inner strip 5 scrapes off the cell fluid adhering to the inner wall of the centrifuge tube body 1, preventing the cell fluid from adhering to the inner wall of the tube and thus preventing it from centrifuging at high speed in the liquid, which would affect its precipitation. The top of the inner shaft 6 is fixed to the bottom surface of the rotating shaft 8.
[0023] In this embodiment, preferably, a rubber sealing sleeve 9 is fitted on the outer wall of the rotating shaft 8, and the outer wall of the rubber sealing sleeve 9 is fixed on the tube cover 2. The rubber sealing sleeve 9 is designed to be set in the outer wall of the rotating shaft 8 and inside the tube cover 2 to seal the gap between the two. The cross-section of the rotating shaft 8 is a circular structure, and the longitudinal section of the rotating shaft 8 is an I-shaped structure. A spherical groove is opened on the inner surface of the rotating shaft 8, and a ball bearing 7 is embedded in the spherical groove. The ball bearing 7 is designed to reduce the frictional resistance between the surface of the rotating shaft 8 and the surface of the tube cover 2.
[0024] In this embodiment, preferably, a support sleeve 11 is fitted on the outer wall of the bottom end of the inner shaft 6. The support sleeve 11 is designed to straighten the inner shaft 6 and prevent the inner shaft 6 from tilting. The support sleeve 11 is fixed on the inner end face of the centrifuge tube 1. The cross-section of the support sleeve 11 is circular. A through hole 10 is opened at the bottom end of the support sleeve 11. The through hole 10 is designed to prevent sample liquid from entering the support sleeve 11 and preventing centrifugal motion. The cross-section of the rotating block 4 is circular. An anti-slip sleeve 3 is fitted on the outer wall of the rotating block 4.
[0025] The working principle and usage process of this utility model are as follows: When processing cell precipitation, the cell solution is loaded into the centrifuge tube 1 and the tube cap 2 is screwed on. At the same time, the bottom end of the inner shaft 6 is inserted into the support sleeve 11. When centrifugation is required, in order to prevent the cell solution from adhering to the inner wall of the tube and thus preventing centrifugal motion, the rotating block 4 is held and the rotating shaft 8 is rotated. The rotating shaft 8 drives the inner strip 5 on the inner shaft 6 to rotate together. The inner strip 5 scrapes off the cell solution adhering to the inner wall of the centrifuge tube 1, thus preventing the cell solution from adhering to the inner wall of the tube and thus preventing it from centrifuging at high speed in the liquid, which would affect its precipitation.
[0026] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A centrifuge tube for cell pellet, comprising a centrifuge tube body (1), the top of the centrifuge tube body (1) is connected with a tube cover (2) through thread, characterized in that: The inner part of the centrifugal tube body (1) is provided with an inner strip (5), one side surface of the inner strip (5) is attached to the inner wall of the centrifugal tube body (1), the other side of the inner strip (5) is connected with an inner shaft (6), the tube cover (2) is rotatably embedded with a rotating shaft (8), the top of the rotating shaft (8) is fixed with a rotating block (4), and the top end of the inner shaft (6) is fixed on the bottom surface of the rotating shaft (8).
2. The cell pellet centrifuge tube of claim 1, wherein: The outer wall of the rotating shaft (8) is sleeved with a rubber sealing sleeve (9), and the outer wall of the rubber sealing sleeve (9) is fixed on the tube cover (2).
3. The cell pellet centrifuge tube of claim 1, wherein: The cross section of the rotating shaft (8) is a circular structure, and the longitudinal section of the rotating shaft (8) is an I-shaped structure.
4. The cell pellet centrifuge tube of claim 3, wherein: The inner side surface of the rotating shaft (8) is provided with a spherical groove, and the spherical groove is embedded with a ball (7).
5. The cell pellet centrifuge tube of claim 1, wherein: The bottom end of the inner shaft (6) is sleeved with a supporting sleeve (11), and the supporting sleeve (11) is fixed on the inner end surface of the centrifugal tube body (1).
6. A cell pellet centrifuge tube according to claim 5, wherein: The cross section of the supporting sleeve (11) is a circular structure, and the bottom end of the supporting sleeve (11) is provided with a through hole (10).
7. The cell pellet centrifuge tube of claim 1, wherein: The cross section of the rotating block (4) is a circular structure, and the outer wall of the rotating block (4) is sleeved with an anti-skid sleeve (3).