Microwell plate centrifugal machine convenient for fixing different microwell plates

By designing an adjustable support frame structure and drive motor transmission connection, the problem that traditional microplate centrifuges cannot fix microplates of different widths has been solved, achieving efficient and stable microplate fixation and liquid sedimentation, thus improving experimental efficiency and cleanliness.

CN223732967UActive Publication Date: 2025-12-30BECKON BIOTECHNOLOGY (DALIAN) CO LTD
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Patent Information

Application Number
CN202423086298.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-13
Publication Date
2025-12-30
Estimated Expiration
2034-12-13

AI Technical Summary

Technical Problem

Traditional microplate centrifuges cannot flexibly fix microplates of different widths, resulting in poor ease of use and applicability, which affects experimental efficiency and sample uniformity.

Method used

An adjustable support frame structure was designed, including a side filter plate, an inner filter plate, and a side frame with elastic connection. Combined with the transmission connection between the drive motor and the support rod, it can stably fix microporous plates of different specifications and quickly settle the liquid through centrifugal force.

Benefits of technology

It improves the ease of use and applicability of microplate centrifuges, ensures the processing efficiency and uniformity of experimental samples, avoids air bubbles or sample loss, and enhances the cleanliness of the centrifugation environment.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of centrifugal machines, in particular to a microplate centrifugal machine convenient for fixing different microplates, and solves the problems that in the prior art, microplates are directly inserted into hole grooves of the microplate centrifugal machine, and then the centrifugal machine is started for centrifugal operation, so that the microplates with different widths are inconvenient to fix and bear, and the working efficiency is high. And an adjusting function is lacked, so that the use convenience of the centrifugal machine is greatly reduced. A microwell plate centrifugal machine facilitating fixing of different microwell plates comprises a frame body, a bearing rod is rotationally connected to the inner side of the frame body, a driving motor is fixedly connected to one side of the bottom of the frame body through bolts, the bottom end of the bearing rod penetrates through the bottom of the frame body and is in transmission connection with an output shaft of the driving motor, and a plurality of bearing frames are fixedly connected to the bearing rod. The utility model solves the problem that the traditional microwell plate centrifugal machine cannot adapt to microwell plates with different widths due to a single fixing mode, and the use convenience and applicability of the centrifugal machine are greatly improved.
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Description

Technical Field

[0001] This utility model relates to the field of centrifuge technology, and in particular to a microporous plate centrifuge that facilitates the fixing of different microporous plates. Background Technology

[0002] Microplates, also known as multiwell plates or microwell array plates, are meticulously designed plates with a surface covered with numerous tiny, uniformly distributed pores. These pores are typically precise to the micrometer level, enabling microplates to serve as highly efficient sample processing and reaction platforms. Microplates play a crucial role in scientific research, medical diagnostics, biological experiments, drug screening, environmental monitoring, and numerous biochemical applications. Their overall design considers not only the size and distribution of the pores but also the material of the plate, surface treatment technology, and compatibility with other experimental equipment. Microplates are made from a variety of materials, including but not limited to plastics, glass, ceramics, and metals, each with unique chemical and physical properties to meet the needs of different experiments. In biological experiments, microplates are commonly used as carriers for cell culture, enzyme-linked immunosorbent assays (ELISA), and polymerase chain reaction (PCR). Each microwell can function as an independent reaction unit, processing multiple samples simultaneously, significantly improving experimental throughput and efficiency. Furthermore, microplates are easily integrated with automated experimental equipment, enabling automated and intelligent experimental procedures.

[0003] A microplate centrifuge is a centrifugation device specifically designed for microplates. It utilizes centrifugal force to rapidly settle the liquid within the microplate, preventing air bubbles or sample loss and ensuring the homogeneity and integrity of experimental samples. This equipment is widely used in PCR experiments, DNA / RNA extraction and purification, enzyme reactions, protein crystallization, cell culture, and other fields.

[0004] When using microplate centrifuges, ensuring the efficiency of the centrifuge is crucial, and securing microplates of different sizes is particularly important. However, traditional microplate centrifuges simply insert the microplate directly into the slots and then start the centrifuge. This method is not convenient for securing and supporting microplates of different widths and lacks adjustment functionality, which greatly reduces the ease of use of the centrifuge and makes it extremely inconvenient. Therefore, there is an urgent need for a microplate centrifuge that can easily secure different microplates to solve the above problems. Utility Model Content

[0005] The purpose of this invention is to provide a microplate centrifuge that facilitates the fixing of different microplates, solving the problem that in the prior art, microplate centrifuges simply insert the microplate into the slot and then start the centrifuge for centrifugation, which is not convenient for fixing and supporting microplates of different widths, lacks adjustment function, and thus greatly reduces the ease of use of the centrifuge.

[0006] To achieve the above objectives, the present invention adopts the following technical solution:

[0007] A microplate centrifuge for easy fixation of different microplates includes a frame, a support rod rotatably connected to the inner side of the frame, a drive motor fixedly connected to the bottom side of the frame by bolts, and the bottom end of the support rod passing through the bottom of the frame and being connected to the output shaft of the drive motor for transmission. Several support frames are fixedly connected to the support rod.

[0008] A side filter plate is provided on one side of the support frame, and insert plates are fixedly connected to both ends of the side filter plate. Both insert plates penetrate the side wall of the support frame. An inner filter plate is fixedly connected to one side of the support frame, and a side frame is provided on one side of the support frame. The two sides of the side frame are fixedly connected to one side of the two insert plates respectively. The two sides of the side frame are elastically connected to one side of the support frame. An adsorption cylinder is fixedly connected to the inner wall of the frame.

[0009] Preferably, a sliding sleeve is fitted on the upper part of the bearing rod, and a limiting plate is fitted on the outer side of the sliding sleeve, and the limiting plate is located at the top of all bearing frames.

[0010] Preferably, a threaded rod is provided on one side of the sliding sleeve, and one end of the threaded rod has a threaded groove that passes through both sides of the sliding sleeve and the bearing rod in sequence.

[0011] Preferably, all insert plates pass through the side walls of all the load-bearing frames sequentially via slots.

[0012] Preferably, each of the support frames is provided with a screw on one side, and one end of the screw passes through the side wall of the support frame and the corresponding insert plate in sequence through a screw groove.

[0013] Preferably, the bottom end of the support rod passes through the bottom of the frame through a bearing sleeve, and the top of the frame is rotatably connected to a top cover via a hinge.

[0014] Preferably, the inner sides of all the side frames are elastically connected to the side walls of all the load-bearing frames by several tension springs.

[0015] Preferably, each screw has several screw slots on one side of the insert plate.

[0016] This utility model has the following beneficial effects:

[0017] This microplate centrifuge, designed for easy fixation of different microplates, achieves flexible fixation of microplates of varying sizes through the adjustable design of the side and inner filter plates on the support frame, and the elastic connection between the side frame and the support frame. This solves the problem of traditional microplate centrifuges being unable to adapt to microplates of different widths due to their single fixation method, greatly improving the centrifuge's ease of use and applicability. Simultaneously, the transmission connection between the drive motor and the support rod, along with the centrifugal force generated during the rotation of the support frame, ensures rapid sedimentation and separation of the liquid within the microplate. This not only improves the processing efficiency and uniformity of experimental samples but also avoids the impact of air bubbles or sample loss on experimental results. Furthermore, the adsorption cylinder on the inner wall of the frame further enhances the cleanliness of the centrifugation environment, providing more reliable conditions for experiments. Attached Figure Description

[0018] To more clearly illustrate the technical solutions of the embodiments of this utility model, the drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0019] Figure 1 This is a schematic diagram of the appearance and structure of this utility model;

[0020] Figure 2 This is a top view of the overall structure of this utility model;

[0021] Figure 3 This is a top view of the inner structure of this utility model;

[0022] Figure 4 This is a schematic diagram of the bearing rod and its structure of the present invention;

[0023] Figure 5 This is a schematic diagram of the bottom structure of the support frame of this utility model;

[0024] Figure 6 This is a top view of the load-bearing frame structure of this utility model;

[0025] Figure 7 This is a schematic diagram of the insert plate extraction structure of this utility model;

[0026] Figure 8 This is a schematic diagram of the side filter plate structure of this utility model.

[0027] In the diagram: 1. Frame; 2. Drive motor; 3. Top cover; 4. Adsorption cylinder; 5. Limiting plate; 6. Sliding sleeve; 7. Threaded rod; 8. Bearing frame; 9. Side filter plate; 10. Bearing rod; 11. Insert plate; 12. Side frame; 13. Tension spring; 14. Inner filter plate; 15. Screw; 16. Threaded groove; 17. Slot. Detailed Implementation

[0028] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present utility model and are not intended to limit the present utility model.

[0029] Reference Figure 1 -8. A microplate centrifuge for easy fixing of different microplates includes a frame 1. A support rod 10 is rotatably connected to the inner side of the frame 1. A drive motor 2 is fixedly connected to the bottom side of the frame 1 by bolts. The bottom end of the support rod 10 passes through the bottom of the frame 1 and is connected to the output shaft of the drive motor 2. The support rod 10 is an important bridge connecting the drive motor 2 and the support frame 8. It not only transmits the rotational power of the drive motor 2, but also realizes the stable bearing and rotation of the microplate through the support frame 8 fixedly connected to it. Several support frames 8 are fixedly connected to the support rod 10.

[0030] A side filter plate 9 is provided on one side of the support frame 8, and insert plates 11 are fixedly connected to both ends of the side filter plate 9. Both insert plates 11 penetrate through the side wall of the support frame 8. An inner filter plate 14 is fixedly connected to one side of the support frame 8. As the direct support structure for the microporous plate, the design of the support frame 8 fully considers the fixation and adaptability of the microporous plate. The side filter plate 9 on one side, through the through connection of the insert plates 11 to the side wall of the support frame 8, allows for flexible adjustment of the position of the side filter plate 9 to accommodate microporous plates of different widths. At the same time, an inner filter plate is also fixedly connected to one side of the support frame 8. 14, together with the side filter plate 9, constitutes a stable fixing structure for the microporous plate. A side frame 12 is provided on one side of the support frame 8, and the two sides of the side frame 12 are fixedly connected to one side of the two insert plates 11 respectively. Both sides of the side frame 12 are elastically connected to one side of the support frame 8. The insert plates 11 also achieve stable fixing and limiting of the side filter plate 9 through the fixed connection with the side frame 12 and the cooperation of the screw groove 16 and the screw 15. An adsorption cylinder 4 is fixedly connected to the inner wall of the frame 1. The liquid centrifuged from the microporous plate can be adsorbed by the adsorption cylinder 4.

[0031] Furthermore, a sliding sleeve 6 is fitted on the upper part of the support rod 10, and a limiting plate 5 is fitted on the outer side of the sliding sleeve 6. The limiting plate 5 is located on the top of all the support frames 8. When the support frames 8 are adjusted according to the microporous plate specifications, the sliding sleeve 6 can slide along the support rod 10 to the appropriate position and limit the top of all the support frames 8 through the limiting plate 5, ensuring the stability of the support frames 8 and the microporous plate during centrifugation, thereby enhancing the overall structural stability and preventing the microporous plate from shaking or falling off.

[0032] Furthermore, a threaded rod 7 is provided on one side of the sliding sleeve 6, and one end of the threaded rod 7 has a threaded groove that passes through both sides of the sliding sleeve 6 and the bearing rod 10 in sequence. Tightening the threaded rod 7 can fix the sliding sleeve 6 and the limiting plate 5 at a specific position on the bearing rod 10, ensuring the durability of the limiting effect. This achieves the effect of conveniently adjusting and fixing the position of the sliding sleeve 6 and the limiting plate 5, and improving the ease of operation.

[0033] Furthermore, all the insert plates 11 pass through the side walls of all the support frames 8 in sequence via the slots 17, so that the insert plates 11 can slide smoothly in the side walls of the support frames 8 and adjust their positions according to the width of the microporous plate, thereby achieving the effect of flexibly adapting to microporous plates of different specifications and improving the versatility of the equipment.

[0034] Furthermore, each of the support frames 8 is provided with a screw 15 on one side, and one end of the screw 15 passes through the side wall of the support frame 8 and the corresponding insert plate 11 in sequence through the screw groove 16. Tightening the screw 15 can limit and fix the adjusted insert plate 11, ensuring the stability of the side filter plate 9, and achieving the effect of firmly fixing the side filter plate 9 and preventing the microporous plate from shifting during centrifugation.

[0035] Furthermore, the bottom end of the support rod 10 passes through the bottom of the frame 1 through a bearing sleeve, and the top of the frame 1 is rotatably connected to the top cover 3 through a hinge. The bearing sleeve ensures the smooth rotation of the support rod 10, while the top cover 3 can be opened or closed when needed, making it convenient to place or remove the microplate, thus ensuring the normal operation of the equipment and facilitating operation.

[0036] Furthermore, the inner sides of all the side frames 12 are elastically connected to the side walls of all the bearing frames 8 by several tension springs 13. The tension springs 13 provide elastic support for the side frames 12, so that the side filter plates 9 can fit tightly against the microporous plates of different widths, while ensuring the stability of the side frames 12 during the adjustment process, thereby improving the fixing effect and enhancing the adaptability of the equipment.

[0037] Furthermore, each of the screws 15 has several screw grooves 16 on one side of the insert plate 11, allowing the screws 15 to be screwed into different positions of the screw grooves 16 as needed. This further improves the adjustment accuracy and fixing stability of the insert plate 11 and the side filter plate 9, achieving the effect of finely adjusting the position of the side filter plate 9 and ensuring the optimal fixing effect of the microporous plate.

[0038] In summary:

[0039] When using this type of microplate centrifuge that facilitates the fixing of different microplates, a series of adjustments must first be made according to the specifications of the microplate to be centrifuged. The specific operation process is as follows: Adjust the distance between the side filter plate 9 and the inner filter plate 14 on the support frame 8 through the elastic connection provided by the tension spring 13 between the side frame 12 and the support frame 8. This adjustment allows the two insert plates 11 to slide smoothly through the slots 17 in the side wall of the support frame 8 and be fixed in a suitable position according to the width of the microplate, thus achieving flexible adaptation to microplates of different specifications. After the adjustment is completed, place the microplate inside the support frame 8. At this time, the side filter plate 9, the inner filter plate 14, and the support frame 8 itself together form a stable fixing structure. To further enhance the stability of this fixing structure, screws 15 are screwed into several screw grooves 16 on the insert plates 11 to limit the position of the insert plates 11, i.e., the side filter plates 9. Simultaneously, the sliding sleeve 6 fitted on the upper part of the support rod 10 can slide along the support rod 10 to an appropriate position, and the limiting plate 5 fitted on its outer side limits the top of all the support frames 8. Tighten the threaded rod 7 on one side of the sliding sleeve 6, so that one end passes through the threaded groove through both sides of the sliding sleeve 6 and the support rod 10 in sequence, fixing the sliding sleeve 6 and the limiting plate 5 at a specific position on the support rod 10, thereby ensuring the stability of the support frames 8 and the microplate during centrifugation. Then, start the drive motor 2, which is fixed to the bottom of the frame 1 by bolts. The output shaft of the drive motor 2 drives the support rod 10 to rotate inside the frame 1 through the transmission connection. Several support frames 8 on the support rod 10 and the microplate inside them also rotate, generating centrifugal force. This centrifugal force causes the liquid in the microplate to settle rapidly, separating different components in the liquid or removing air bubbles, thereby ensuring the uniformity and integrity of the experimental samples. During centrifugation, the adsorption cylinder 4 on the inner wall of the frame 1 can further assist in adsorbing any splashes or impurities that may be generated inside the microplate, keeping the centrifugation environment clean. Meanwhile, the bottom end of the support rod 10 passes through the bottom of the frame 1 via a bearing sleeve, ensuring smooth rotation of the support rod 10. The top cover 3, which is hinged to the top of the frame 1, can be easily opened or closed when needed, facilitating the placement or removal of the microporous plate.

[0040] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. A microplate centrifuge for facilitating the fixation of different microplates, comprising a frame (1), characterized in that, The inner side of the frame (1) is rotatably connected with a bearing rod (10), the bottom side of the frame (1) is fixedly connected with a driving motor (2) through bolts, and the bottom end of the bearing rod (10) penetrates the bottom of the frame (1) and is in transmission connection with the output shaft of the driving motor (2); a plurality of bearing frames (8) are fixedly connected on the bearing rod (10); The side of the bearing frame (8) is provided with a side filter plate (9), both ends of the side filter plate (9) are fixedly connected with plug-in plates (11), both plug-in plates (11) penetrate the side wall of the bearing frame (8), the side of the bearing frame (8) is fixedly connected with an inner filter plate (14), the side of the bearing frame (8) is provided with a side frame (12), and both sides of the side frame (12) are fixedly connected with one side of the two plug-in plates (11), both sides of the side frame (12) are elastically connected with the side of the bearing frame (8), the inner wall of the frame (1) is fixedly connected with an adsorption cylinder (4), the upper part of the bearing rod (10) is sleeved with a sliding sleeve (6), the outer side of the sliding sleeve (6) is sleeved with a limiting plate (5), the limiting plate (5) is located at the top of all bearing frames (8), one side of the sliding sleeve (6) is provided with a threaded rod (7), one end of the threaded rod (7) is threaded into the sliding sleeve (6) and the bearing rod (10) in sequence, both sides of the inner side of all side frames (12) are elastically connected with the side wall of all bearing frames (8) through a plurality of extension springs (13).

2. A microplate centrifuge for facilitating the securing of different microplates as claimed in claim 1, wherein, All plug-in plates (11) penetrate the side wall of all bearing frames (8) through plug-in grooves (17) in sequence.

3. A microplate centrifuge for facilitating the securing of different microplates as claimed in claim 1, wherein, One side of all bearing frames (8) is provided with a screw rod (15), and one end of the screw rod (15) penetrates the side wall of the bearing frame (8) and the corresponding plug-in plate (11) through a screw groove (16) in sequence.

4. The microplate centrifuge of claim 1, wherein, The bottom end of the bearing rod (10) penetrates the bottom of the frame (1) through a bearing sleeve, and the top of the frame (1) is rotatably connected with a top cover (3) through a hinge.

5. A microplate centrifuge for facilitating the securing of different microplates as claimed in claim 3, wherein, The screw groove (16) on the plug-in plate (11) on one side of all screw rods (15) is provided with a plurality of screw grooves.