Bioreactor with multiple sample inlets

Abstract

The utility model relates to the technical field of bioreactor equipment, in particular to a bioreactor with multiple sample inlets, which comprises a main body and a stirrer, the stirrer is mounted on the main body, a connecting pipe is arranged at the upper end of the main body, a fixing component is arranged between the connecting pipe and the main body, and the fixing component is mounted on the main body. A connecting pipe is arranged at the upper end of the main body, a fixing ring is arranged on the connecting pipe, a first connector is arranged on the fixing ring, and a second connector is installed on the side face of the main body. Various substances are better fed into the main body, the distribution effect and the mixing uniformity of the substances are improved, and the substances needing to be rapidly and uniformly mixed can be put at the position close to the stirrer through the connector II and are rapidly dispersed by virtue of the stirring effect, so that the distribution and mixing uniformity of different substances is met, and the reaction effect is ensured.

Description

TECHNICAL FIELD

[0001] The application relates to the technical field of a bioreactor device, in particular to a bioreactor with multiple sample inlets. BACKGROUND

[0002] The bioreactor refers to a device system for performing biochemical reactions in vitro by using enzymes or biological functions of organisms, is a biological function simulation machine, and provides a suitable environment, promotes mass transfer and mixing, energy conversion and utilization.

[0003] Through retrieval, the bioreactor with multiple sample inlets disclosed in Chinese Patent No. CN219314916U comprises a sample inlet arranged at the top of a reactor main body, a blocking prevention mechanism arranged on the outer wall of the sample inlet, a first silica gel pipe arranged in the sample inlet, a first water stop clamp arranged on the first silica gel pipe, a first tee pipe arranged at the bottom of the first silica gel pipe, and a first feeding mechanism and a second feeding mechanism arranged on the first tee pipe. The bioreactor with multiple sample inlets can connect multiple feeding external bottles through one sample inlet, improves the external connection efficiency of the bioreactor, and avoids the formation of an arch-shaped structure of feeding materials near the sample inlet and the first silica gel pipe.

[0004] In view of the related technologies in the prior art, the inventors find that the prior art has the following defects: in the prior art, due to the different types and quantities of various nutrients, additives and the like required in the biological reaction process and the different adding frequencies and time intervals of the various nutrients, additives and the like, only one sample inlet is provided, so that the separate addition of different substances cannot be met, and due to the insufficient sample inlets, the addition is disordered or delayed, thereby affecting the reaction effect. In order to solve the problem that the separate addition of different substances cannot be met in the prior art, the sample inlets are distributed at different positions of the reactor, so that the separate addition of different substances is realized, the distribution and mixing uniformity of different substances are met, and the reaction effect is ensured. CONTENT OF THE UTILITY MODEL

[0005] In order to meet the distribution and mixing uniformity of different substances and ensure the reaction effect, the application provides a bioreactor with multiple sample inlets.

[0006] The bioreactor with multiple sample inlets provided by the application adopts the following technical scheme: a main body and a stirrer are arranged, the stirrer is arranged on the main body, a connecting pipe is arranged at the upper end of the main body, a fixing assembly is arranged between the connecting pipe and the main body, a fixing ring is arranged on the connecting pipe, a connecting head one is arranged on the fixing ring, a connecting head two is arranged on the side surface of the main body, and the connecting head one and the connecting head two are both provided with multiple connecting heads.

[0007] Optionally, the fixing assembly comprises a fixing plate, the fixing plate is installed on the upper end of the main body, the lower end of the connecting pipe is provided with an insertion block, the fixing plate is provided with an insertion slot, the insertion block is inserted with the insertion slot, and a limiting piece is arranged between the insertion block and the fixing plate.

[0008] Optionally, the limiting piece comprises a limiting block, the limiting block is slidingly installed on the fixing plate, one side of the limiting block close to the insertion block is provided with a protruding block, one end of the protruding block close to the insertion block is provided with a chamfer, and the protruding block is slidingly provided with a limiting slot at the corresponding position of the insertion block.

[0009] Optionally, the limiting piece further comprises a screw rod, the screw rod is rotationally installed on the fixing plate, and the screw rod is in threaded connection with the limiting block.

[0010] Optionally, the screw rod is provided with two, the two screw rods are symmetrically arranged on the fixing plate, the fixing plate is provided with a cavity, and the limiting block is slidingly arranged in the cavity.

[0011] Optionally, the second connecting head is vertically arranged, the second connecting head is provided with a cover plate on one side, the cover plate is rotationally connected between one side of the cover plate and the main body, and the cover plate is provided with a buckle between the other side of the cover plate and the main body.

[0012] Optionally, the second connecting head is provided with a sealing cover, the sealing cover is in threaded connection with the second connecting head, the first connecting head is in rotation connection with the fixing ring, and the first connecting head is provided with a sealing gasket between the first connecting head and the fixing ring.

[0013] In summary, the present application has the following beneficial technical effects:

[0014] 1. The utility model discloses a first connecting head, second connecting head and other components are set up, and in the working process, the first connecting head of the upper end of the main body and the second connecting head of the lateral side of the main body are matched with each other, realize that various substances are sent into the main body better, and the effect of substance distribution and mixing uniformity is improved, for the substance that needs to be mixed evenly quickly, the second connecting head can be placed in the position close to the stirrer, and the stirring effect is used to disperse quickly, thereby meeting different substance distribution and mixing uniformity, and guaranteeing reaction effect.

[0015] 2. The utility model discloses a fixing plate, insertion block, limiting block, protruding block, screw rod and other components are set up, and in the working process, the insertion block component and the insertion slot component are matched with each other, thereby limiting the installation position of the connecting pipe, and the screw rod component, limiting block component and protruding block component are matched with each other, the rotation of screw rod component is adjusted, the limiting block is driven to move along with the protruding block by screw rod component, and is matched with the limiting slot on the insertion block, thereby realizing the convenient clamping fixing of the connecting pipe. BRIEF DESCRIPTION OF DRAWINGS

[0016] Figure 1 is a schematic diagram of the overall structure in the embodiment of the application;

[0017] Figure 2 is a schematic diagram of the second position of the connecting head in the embodiment of the application;

[0018] Figure 3 is a schematic diagram of the local structure in the embodiment of the application;

[0019] Figure 4 is a sectional view of the fixing plate in the embodiment of the application.

[0020] Reference signs: 1, main body; 2, stirrer; 3, connecting pipe; 4, fixing ring; 5, first connecting head; 6, fixing plate; 7, insertion block; 8, insertion slot; 9, limiting block; 10, protruding block; 11, limiting slot; 12, screw rod; 13, second connecting head; 14, cover plate; 15, buckle; 16, sealing cover. DETAILED DESCRIPTION

[0021] The following will be described in detail in combination with the accompanying Figures 1-4 The application is further described in detail.

[0022] The embodiment of the application discloses a bioreactor with multiple sample inlets. As shown in Figure 1 , Figure 2 , Figure 4 , the bioreactor comprises a main body 1 and a stirrer 2, the stirrer 2 is installed on the main body 1, a connecting pipe 3 is arranged at the upper end of the main body 1, a fixing assembly is arranged between the connecting pipe 3 and the main body 1, the fixing assembly comprises a fixing plate 6, the fixing plate 6 is installed on the upper end of the main body 1, an insertion block 7 is installed at the lower end of the connecting pipe 3, an insertion slot 8 is arranged on the fixing plate 6, the insertion block 7 is inserted into the insertion slot 8, in the process of installing the connecting pipe 3, the position of the connecting pipe 3 is limited by matching the insertion block 7 with the insertion slot 8, so that the connecting pipe 3 is prevented from rotating.

[0023] Please refer to Figure 3 , Figure 4 , a limiting piece is arranged between the insertion block 7 and the fixing plate 6, the limiting piece comprises a limiting block 9, the limiting block 9 is slidingly installed on the fixing plate 6, a protruding block 10 is arranged on the side of the limiting block 9 close to the insertion block 7, one end of the protruding block 10 close to the insertion block 7 is chamfered, a limiting slot 11 is arranged on the insertion block 7 at a position corresponding to the protruding block 10, the protruding block 10 and the limiting slot 11 are slidingly arranged, the position of the insertion block 7 is limited by inserting the protruding block 10 into the limiting slot 11, so that the position of the connecting pipe 3 is indirectly limited, and the connecting pipe 3 is prevented from being separated from the fixing plate 6.

[0024] Please refer to Figure 4The limiting piece further comprises a screw rod 12, which is rotatably installed on the fixed plate 6, and is in threaded connection with the limiting block 9. Two screw rods 12 are symmetrically arranged on the fixed plate 6. By driving the two screw rods 12 to rotate, the screw rod 12 drives the limiting block 9 to move. The protrusions 10 on the two limiting blocks 9 clamp and limit the plug block 7, so that the plug block 7 is uniformly stressed on both sides. By reversely driving the screw rod 12 to rotate, the screw rod 12 drives the limiting block 9 to move in a direction, so that the protrusion 10 is separated from the limiting groove 11, thereby releasing the limitation on the connecting pipe 3, and the connecting pipe 3 can be disassembled.

[0025] In combination Figure 1 , Figure 2 The fixed plate 6 is provided with a cavity, the limiting block 9 is slidably arranged in the cavity, the connecting pipe 3 is provided with a fixed ring 4, the fixed ring 4 is provided with a connecting head one 5, and the main body 1 is provided with a connecting head two 13. The added substances can be fed from different heights of the main body 1, and work in cooperation with the stirrer 2, so that some substances that need to be quickly and uniformly mixed can be quickly and uniformly stirred and dispersed.

[0026] In the embodiment, the connecting head two 13 is provided with a sealing cover 16, the sealing cover 16 is in threaded connection with the connecting head two 13, the connecting head one 5 is in rotational connection with the fixed ring 4, the connecting head one 5 is adjusted to different orientations, so that the work personnel can distinguish different containers, a sealing gasket is arranged between the connecting head one 5 and the fixed ring 4, the connecting head one 5 and the connecting head two 13 are both provided with a plurality of sealing gaskets, the connecting head two 13 is vertically arranged, one side of the connecting head two 13 is provided with a cover plate 14, one side of the cover plate 14 is in rotational connection with the main body 1, and the other side of the cover plate 14 is provided with a buckle 15.

[0027] The implementation principle of the biological reactor with multiple sample inlets is as follows: before work, the connecting head one 5 and the connecting head two 13 are connected with different substance storage devices outside through silica gel pipes, and the unnecessary connecting head one 5 and the connecting head two 13 are plugged by the sealing cover 16. The types and quantities of various nutrients, additives and the like required in the biological reaction process, and their adding frequency and time interval are added individually according to the application situation and requirements, so as to avoid adding confusion or delay caused by insufficient sample inlets.

[0028] The above are preferred embodiments of the present application, and do not limit the protection scope of the present application. Therefore, equivalent changes made on the basis of the structure, shape and principle of the present application should be covered within the protection scope of the present application.

Claims

1. A bioreactor having multiple inlets, comprising a main body (1) and a stirrer (2), characterized in that: The stirrer (2) is installed on the main body (1). A connecting pipe (3) is provided at the upper end of the main body (1). A fixing component is provided between the connecting pipe (3) and the main body (1). A fixing ring (4) is provided on the connecting pipe (3). A connector head one (5) is provided on the fixing ring (4). A connector head two (13) is installed on the side of the main body (1). Multiple connector heads one (5) and connector head two (13) are provided.

2. A bioreactor with multiple sample inlets according to claim 1, characterized in that: The fixing component includes a fixing plate (6), which is installed on the upper end of the main body (1). A plug (7) is installed on the lower end of the connecting pipe (3). A slot (8) is provided on the fixing plate (6). The plug (7) is inserted into the slot (8). A limiting member is provided between the plug (7) and the fixing plate (6).

3. A bioreactor with multiple sample inlets according to claim 2, characterized in that: The limiting component includes a limiting block (9), which is slidably mounted on the fixing plate (6). A protrusion (10) is provided on the side of the limiting block (9) near the insert (7), and the end of the protrusion (10) near the insert (7) is chamfered. A limiting groove (11) is provided on the insert (7) at the position corresponding to the protrusion (10), and the protrusion (10) and the limiting groove (11) are slidably disposed.

4. A bioreactor with multiple sample inlets according to claim 3, characterized in that: The limiting component also includes a screw (12), which is rotatably mounted on the fixing plate (6) and is threadedly connected to the limiting block (9).

5. A bioreactor with multiple sample inlets according to claim 4, characterized in that: There are two screws (12), which are symmetrically arranged on the fixing plate (6). The fixing plate (6) has a cavity, and the limiting block (9) is slidably arranged in the cavity.

6. A bioreactor with multiple sample inlets according to claim 1, characterized in that: The second connector (13) is vertically arranged. A cover plate (14) is provided on one side of the second connector (13). One side of the cover plate (14) is rotatably connected to the main body (1). A buckle (15) is provided between the other side of the cover plate (14) and the main body (1).

7. A bioreactor with multiple sample inlets according to claim 1, characterized in that: A sealing cap (16) is provided on the second connector (13). The sealing cap (16) is threadedly connected to the second connector (13). The first connector (5) is rotatably connected to the fixing ring (4). A sealing gasket is provided between the first connector (5) and the fixing ring (4).

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