Biological organ 3D printer

Abstract

The utility model relates to the technical field of biological printing equipment, and discloses a biological organ 3D printer which comprises a machine body, a lifting door and an air filtering assembly, the machine body comprises a top, a bottom and a side part, the side part is connected between the top and the bottom, and a working space is formed among the top, the bottom and the side part; a working platform is arranged at the bottom, and the working space is located above the working platform; the lifting door is movably connected to the side part in the vertical direction and is used for opening or closing the working space; the air filtering assembly is connected to the top and / or the side part; and the air filtering assembly is located above the working space, is opposite to the working platform and is used for discharging air towards the working platform, so that the space occupied by the 3D printer for the biological organs in the transverse direction can be reduced.

Description

Technical Field

[0001] This utility model relates to the field of bioprinting equipment technology, specifically to a biological organoid 3D printer. Background Technology

[0002] Organoids are 3D organs that are grown in vitro using the self-organizing ability of stem cells. They can highly simulate real organs in structure and function and are known as "human organ models in a petri dish". A bio-organoid 3D printer is a device used to print 3D organs.

[0003] Among related technologies, biological organoid 3D printers occupy a large horizontal space, making it difficult to meet users' needs. Utility Model Content

[0004] This invention aims to solve at least one of the technical problems existing in the prior art. To this end, this invention proposes a biological organoid 3D printer that can reduce the horizontal space occupied by the biological organoid 3D printer.

[0005] The biological organoid 3D printer according to an embodiment of the present invention includes a body, a lifting door, and an air filtration assembly. The body includes a top, a bottom, and a side, with the side connected between the top and the bottom, forming a workspace between the top, bottom, and side. The bottom has a work platform, and the workspace is located above the work platform. The lifting door is movably connected to the side in a vertical direction for opening or closing the workspace. The air filtration assembly is connected to the top and / or the side. The air filtration assembly is located above the workspace and is disposed opposite to the work platform for discharging air toward the work platform.

[0006] The biological organoid 3D printer according to the embodiments of this utility model has at least the following beneficial effects: By placing the air filter assembly above the workspace and opposite to the work platform, the air filter assembly is used to discharge air towards the work platform. This allows the air filter assembly to deliver clean airflow vertically towards the work platform, forming an air curtain. This reduces contamination of the liquid in the storage holes of the perforated plate placed on the work platform by microorganisms, dust, and other impurities, thus helping to improve the success rate of experiments. By setting the lifting door to be movably connected to the side in the vertical direction for opening or closing the workspace, compared to the side-rotating door opening and closing method in related technologies, the lifting door in this embodiment adopts a vertical opening and closing method. This better utilizes the vertical space of the biological organoid 3D printer, thereby reducing the horizontal space occupied by the biological organoid 3D printer and meeting the user's needs.

[0007] According to some embodiments of the present invention, the air filtration assembly includes a filter component and an air outlet component, both of which are connected to the top and / or side, and the filter component and the working platform are arranged opposite to each other; the air outlet component is located on the side of the filter component facing away from the working space and is used to discharge air toward the filter component.

[0008] According to some embodiments of the present invention, the air filtration assembly further includes a mounting cover, which is connected to the top and / or side; the mounting cover has a receiving cavity, and the filter component is disposed in the receiving cavity; the receiving cavity has a top wall and a bottom wall spaced apart in the vertical direction, the bottom wall has a plurality of air passage holes, each air passage hole is connected to the receiving cavity and the working space, the top wall has an installation port, and the air outlet component is connected to the installation port.

[0009] According to some embodiments of the present invention, the biological organoid 3D printer further includes a first guide rail and a first slider. The first guide rail is connected to the side and extends in the vertical direction; the first slider is slidably connected to the first guide rail, and a lifting door is connected to the first slider.

[0010] According to some embodiments of the present invention, a first slide groove is provided on the side of the side facing the work space. The first slide groove extends in a vertical direction. A first guide rail and a first slider are both provided in the first slide groove. The lifting door is movably inserted in the first slide groove in a vertical direction.

[0011] According to some embodiments of the present invention, the biological organoid 3D printer further includes a first roller, a counterweight, and a connecting rope. The first roller is connected to the side. The connecting rope is wound around the first roller, and its two ends are respectively connected to the first slider and the counterweight.

[0012] According to some embodiments of the present invention, the counterweight and the lifting door have equal weights; and / or, the biological organoid 3D printer further includes a second roller, with the first roller disposed above the first guide rail; the second roller is located on the side of the first roller away from the lifting door and is connected to the side; and a connecting rope is wound around the second roller.

[0013] According to some embodiments of the present invention, the workspace is located on one side of the side portion along the first horizontal direction; the biological organoid 3D printer also includes a second guide rail and a second slider, the second guide rail being connected to the side portion and being spaced apart from the first guide rail along the second horizontal direction, the first horizontal direction and the second horizontal direction being set at an angle; the second guide rail extends in the vertical direction, the second slider is slidably connected to the second guide rail, and the lifting door is connected to the second slider.

[0014] According to some embodiments of the present invention, a clearance opening is provided at the top, the shape of which is adapted to the shape of the lifting door, and the lifting door is movably inserted through the clearance opening in the vertical direction.

[0015] According to some embodiments of the present invention, the biological organoid 3D printer also includes a buffer connected to the bottom and located in the descent path of the lifting door.

[0016] Additional aspects and advantages of this invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. Attached Figure Description

[0017] The present invention will be further described below with reference to the accompanying drawings and embodiments, wherein:

[0018] Figure 1 A schematic diagram of the structure of the biological organoid 3D printer provided in an embodiment of the present invention is shown;

[0019] Figure 2 This shows a partial structural schematic diagram from another perspective of the biological organoid 3D printer provided in an embodiment of the present invention;

[0020] Figure 3 This shows a partial structural schematic diagram from another perspective of the biological organoid 3D printer provided in an embodiment of the present invention;

[0021] Figure 4 This illustration shows a partial structural diagram of the biological organoid 3D printer provided in an embodiment of the present invention from another perspective.

[0022] Figure label:

[0023] 3D printer for biological organoids 100; body 110; top 111; clearance opening 1111; bottom 113; work platform 1131; side 115; first slide 1151; second slide 1153; workspace 117; lifting door 130; air filter assembly 150; filter component 151; air outlet component 153; mounting cover 155; air vent 1551; first guide rail 170; first slider 190; first roller 210; counterweight 230; connecting rope 250; second roller 270; second guide rail 290; second slider 310; buffer 330;

[0024] Vertical direction Z; First horizontal direction X; Second horizontal direction Y. Detailed Implementation

[0025] The embodiments of this utility model are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain this utility model, and should not be construed as limiting this utility model.

[0026] In the description of this utility model, it should be understood that the directional descriptions, such as up, down, front, back, left, right, etc., indicate the directional or positional relationship based on the directional or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0027] In the description of this utility model, "several" means one or more, "multiple" means two or more, "greater than," "less than," and "exceeding" are understood to exclude the stated number, while "above," "below," and "within" are understood to include the stated number. The use of "first" and "second" in the description is merely for distinguishing technical features and should not be construed as indicating or implying relative importance, or implicitly indicating the number of indicated technical features, or implicitly indicating the order of the indicated technical features.

[0028] In the description of this utility model, unless otherwise explicitly defined, terms such as "setting," "installation," and "connection" should be interpreted broadly, and those skilled in the art can reasonably determine the specific meaning of the above terms in this utility model in conjunction with the specific content of the technical solution.

[0029] In the description of this utility model, the terms "one embodiment," "some embodiments," "illustrative embodiment," "example," "specific example," or "some examples," etc., refer to specific features, structures, materials, or characteristics described in connection with that embodiment or example, which are included in at least one embodiment or example of this utility model. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0030] Please see Figures 1 to 2 This application provides a biological organoid 3D printer 100, including a body 110, a lifting door 130, and an air filter assembly 150.

[0031] The body 110 includes a top 111, a bottom 113, and a side 115. The side 115 connects the top 111 and the bottom 113. The top 111 is spaced above the bottom 113. A working space 117 is formed between the top 111, the bottom 113, and the side 115. The bottom 113 has a working platform 1131, and the working space 117 is located above the working platform 1131.

[0032] As an example, the working platform 1131 can be used to mount a well plate, a first drive structure to move the well plate, etc. The well plate can be provided with several liquid storage holes, which can be used to contain liquids such as reagents, samples, and culture media. The top 111 can be used to mount a second drive structure, etc., which is used to drive the liquid dispensing needle to move, so as to realize actions such as extracting liquid and adding liquid into the liquid storage holes of the well plate. The specific structure and working process of the biological organoid 3D printer 100 can be referred to the prior art, and will not be described in detail in this application.

[0033] The air filter assembly 150 is connected to the top 111 and / or the side 115. The air filter assembly 150 is located above the workspace 117 and is positioned opposite the work platform 1131. The air filter assembly 150 is used to discharge air toward the work platform 1131, so that the air filter assembly 150 can deliver clean airflow toward the work platform 1131 in the vertical direction Z, which can form an air curtain to reduce the contamination of the liquid in the liquid storage hole of the perforated plate placed on the work platform 1131 by microorganisms, dust and other impurities, and help improve the success rate of the experiment.

[0034] The lifting door 130 is movably connected to the side 115 along the vertical direction Z, and is used to open or close the workspace 117. Thus, compared with the door opening and closing method of the related technology where the door body rotates on the side, the lifting door 130 in this embodiment adopts the opening and closing method along the vertical direction Z, which can better utilize the space of the biological organoid 3D printer 100 in the vertical direction Z, thereby reducing the space occupied by the biological organoid 3D printer 100 in the horizontal direction and meeting the user's needs.

[0035] In some embodiments, the air filtration assembly 150 may include a filter element 151 and an air outlet element 153.

[0036] The filter component 151 and the air outlet component 153 are both connected to the top 111 and / or the side 115. For example, the filter component 151 and the air outlet component 153 are both disposed inside the top 111.

[0037] The filter element 151 can be located above the workspace 117, and the filter element 151 can be arranged opposite to the work platform 1131. The air outlet element 153 can be located on the side of the filter element 151 facing away from the workspace 117, and is used to exhaust air towards the filter element 151. The airflow from the air outlet element 153 can pass through the filter element 151, and the airflow filtered by the filter element 151 can be blown towards the work platform 1131 to form a clean airflow, reducing the possibility of microorganisms, dust and other impurities contaminating the liquid in the liquid storage holes of the perforated plate.

[0038] The filter element 151 can be a high-efficiency particulate air (HEPA) filter or other filter components. The air outlet element 153 can be a fan or other air outlet device.

[0039] Please see Figures 1 to 3 In some embodiments, the air filtration assembly 150 may also include a mounting cover 155.

[0040] The mounting cover 155 can be connected to the top 111 and / or the side 115 and is located above the working space 117. For example, the mounting cover 155 can be located inside the top 111. The connection between the mounting cover 155 and the top 111 can be by snap-fit, fastener connection or other connection methods. The fastener can be a screw, bolt, rivet or other fastener.

[0041] The mounting cover 155 may have a receiving cavity, in which the filter element 151 is located. Thus, the mounting cover 155 can protect the filter element 151 and reduce the entry of microorganisms, dust and other impurities into the receiving cavity, thereby reducing the filtration load on the filter element 151 and extending its service life.

[0042] The accommodating cavity may have a top wall and a bottom wall spaced apart along the vertical direction Z. The top wall may be spaced above the bottom wall, and the filter component 151 may be disposed between the top wall and the bottom wall.

[0043] The top wall can be provided with an installation port, and the air outlet component 153 can be connected to the installation port. The bottom wall can be provided with several air passage holes 1551. Each air passage hole 1551 is connected to the accommodating cavity and the working space 117. Thus, the airflow blown by the air outlet component 153 toward the filter component 151 is filtered by the filter component 151 and can be blown toward the working platform 1131 through the air passage holes 1551. This helps to make the overall structure of the air filter assembly 150 more compact. In addition, the air outlet component 153 can act as a shield at the installation port, reducing the entry of dust, microorganisms, etc. into the accommodating cavity and further reducing the filtration load of the filter component 151.

[0044] In some embodiments, the biological organoid 3D printer 100 may further include a first guide rail 170 and a first slider 190.

[0045] The first guide rail 170 can be connected to the side portion 115 and can extend vertically in the Z direction. The first slider 190 is slidably connected to the first guide rail 170, and the lifting door 130 is connected to the first slider 190. Thus, the lifting door 130 is slidably connected to the first guide rail 170 via the first slider 190 to achieve up and down movement, which helps the lifting door 130 move more smoothly. For example, the first guide rail 170 can be connected to the side of the side portion 115 facing the workspace 117.

[0046] The number of first sliders 190 can be one or more, with "more" referring to two or more. When there are multiple first sliders 190, it helps to make the vertical movement of the lifting door 130 more stable, reducing the possibility of the lifting door 130 tipping over.

[0047] In some embodiments, the side of the side portion 115 facing the workspace 117 may be provided with a first groove 1151.

[0048] The first slide groove 1151 can extend vertically in the Z direction. The first guide rail 170 and the first slider 190 can both be disposed in the first slide groove 1151. The lifting door 130 is movably disposed in the first slide groove 1151 in the vertical Z direction. This helps to extend the distance that the gas flows through the first slide groove 1151 between the working space 117 and the external space, and reduces the flow of gas in the gap between the lifting door 130 and the inner wall of the first slide groove 1151. This can reduce the situation where the airflow blown out by the air filter assembly 150 flows out from the gap between the lifting door 130 and the side 115, causing the air curtain to be interrupted, or can prevent the external airflow from flowing into the working space 117 from the gap between the lifting door 130 and the side 115 and interrupting the air curtain. This helps the airflow blown out by the air filter assembly 150 to form a more stable air curtain, and further reduces the situation where dust, microorganisms and other impurities contaminate the liquid in the liquid storage hole of the orifice plate.

[0049] As an example, the first chute 1151 may include a chute opening, a chute bottom wall, and two chute side walls. The chute opening and the chute bottom wall may be spaced apart and opposite to each other along a first horizontal direction X, and the chute opening may be located on one side of the chute bottom wall along the side portion 115 toward the working space 117. The two chute side walls may be spaced apart and opposite to each other along a second horizontal direction Y, and both may extend from the chute opening to the chute bottom wall. The first horizontal direction X and the second horizontal direction Y may be arranged at an angle, for example, the first horizontal direction X and the second horizontal direction Y may be perpendicular to each other, and both the first horizontal direction X and the second horizontal direction Y may be perpendicular to the vertical direction Z.

[0050] The first guide rail 170 can be connected to the bottom wall of the groove, and the edge of the lifting door 130 on one side of the second horizontal direction Y can be inserted into the groove through the opening and connected to the first slider 190.

[0051] It should be noted that the distance between the groove opening and the bottom wall of the groove can be flexibly set according to the requirements to extend the airflow path and reduce the flow of air in the gap between the lifting door 130 and the inner wall of the groove. For example, the distance between the groove opening and the bottom wall of the groove can be ≥5 cm.

[0052] Please see Figure 1 , Figure 3 and Figure 4 In some embodiments, the biological organoid 3D printer 100 may also include a first roller 210, a counterweight 230, and a connecting rope 250.

[0053] The first roller 210 is connected to the side portion 115, for example, the first roller 210 is connected to one side of the side portion 115 along the second horizontal direction Y.

[0054] The connecting rope 250 can be wound around the first roller 210, and its two ends are respectively connected to the first slider 190 and the counterweight 230. The counterweight 230 can reduce the weight of the lifting door 130 when it is opened, thereby reducing the difficulty of opening the door and improving the user experience.

[0055] The first roller 210 can be flush with the upper part of the first guide rail 170, or the first roller 210 can be higher than the upper part of the first guide rail 170, which helps the first roller 210 to form a fulcrum to support the connecting rope 250. The first roller 210 can be a fixed pulley.

[0056] In some embodiments, the weights of the counterweight 230 and the lifting door 130 can be equal or approximately equal, thereby allowing the lifting door 130 to be suspended at any height without requiring the user to manually support the lifting door 130 for an extended period of time, resulting in a better user experience.

[0057] In some embodiments, the biological organoid 3D printer 100 may further include a second roller 270.

[0058] The first roller 210 can be located above the first guide rail 170, and the second roller 270 is located on the side of the first roller 210 away from the lifting door 130. The second roller 270 can be connected to the side 115, and the connecting rope 250 can be wound around the second roller 270, so that the position of the counterweight 230 can be arranged more flexibly, reducing the interference between the counterweight 230 and other structures.

[0059] The second roller 270 can be a fixed pulley.

[0060] In some embodiments, the biological organoid 3D printer 100 may further include a second guide rail 290 and a second slider 310.

[0061] The workspace 117 can be located on one side of the side portion 115 along the first horizontal direction X. The second guide rail 290 is connected to the side portion 115 and is spaced apart from the first guide rail 170 along the second horizontal direction Y. The second guide rail 290 can extend along the vertical direction Z. The second slider 310 is slidably connected to the second guide rail 290. The lifting door 130 is connected to the second slider 310, so that the two edges of the lifting door 130 along the second horizontal direction Y can be connected to the first slider 190 and the second slider 310 respectively, which helps the lifting door 130 move more smoothly and stably, and further reduces the possibility of the lifting door 130 tipping over. For example, the second guide rail 290 can be connected to the side of the side portion 115 facing the workspace 117.

[0062] The number of second sliders 310 can be one or more, with "more" referring to two or more. When there are multiple second sliders 310, it helps to make the vertical movement of the lifting door 130 more stable, reducing the possibility of the lifting door 130 tipping over.

[0063] In some embodiments, a second groove 1153 may be provided on the side of the side portion 115 facing the workspace 117.

[0064] The first slide groove 1151 and the second slide groove 1153 are spaced apart along the second horizontal direction Y. The second slide groove 1153 extends along the vertical direction Z. The second guide rail 290 and the second slider 310 are both disposed within the second slide groove 1153. The lifting door 130 is movably inserted through the second slide groove 1153 along the vertical direction Z. This helps to extend the distance the gas travels through the second slide groove 1153 between the working space 117 and the external space, and reduces the gas flow distance between the lifting door 130 and the second slide groove 1153. The flow of air through the gaps between the inner walls can reduce the possibility of the airflow blown out by the air filter assembly 150 flowing out through the gap between the lifting door 130 and the side 115, thus interrupting the air curtain. Alternatively, it can prevent external airflow from flowing into the working space 117 through the gap between the lifting door 130 and the side 115, thus interrupting the air curtain. This helps the airflow blown out by the air filter assembly 150 to stably sweep the perforated plate and form a more stable air curtain, further reducing the possibility of dust, microorganisms, and other impurities contaminating the liquid in the liquid storage holes of the perforated plate.

[0065] The second slide groove 1153 and the first slide groove 1151 have roughly the same structure, and will not be described in detail here.

[0066] In some embodiments, the top 111 may cover the side portion 115 to shield the upper parts of the first roller 210, the second roller 270, the first guide rail 170, and the second guide rail 290, thereby improving the aesthetic appearance of the biological organoid 3D printer 100. The side portion 115 may have a cavity for mounting other structures of the biological organoid 3D printer 100; the counterweight 230 and the connecting rope 250 may both be located within the cavity, further enhancing the aesthetic appearance of the biological organoid 3D printer 100.

[0067] In some embodiments, the top 111 may be provided with a clearance opening 1111.

[0068] The shape of the clearance opening 1111 is adapted to the shape of the lifting door 130. The lifting door 130 is movably inserted through the clearance opening 1111 in the vertical direction Z, so that the clearance opening 1111 can avoid the lifting door 130, allowing the lifting door 130 to move upward to open the work space 117 and move downward to close the work space 117.

[0069] In some embodiments, the clearance 1111 can extend through the top 111 in the vertical direction Z, and the lifting door 130 can be partially moved above the top 111.

[0070] In some embodiments, the biological organoid 3D printer 100 may also include a buffer 330.

[0071] The buffer 330 is connected to the bottom 113 and located in the descent path of the lifting door 130, which helps to prevent the lifting door 130 from hitting the bottom 113 during descent, helps to reduce noise, and can extend the service life of the lifting door 130.

[0072] As an example, the bottom 113 may be provided with a mounting groove, which may be open upwards and may communicate with the first slide groove 1151 or the second slide groove 1153. The buffer 330 may be connected within the mounting groove. Taking the connection between the mounting groove and the first slide groove 1151 as an example, the buffer 330 may be a hydraulic buffer, and the end of the shaft of the hydraulic buffer may extend upwards to partially enter the first slide groove 1151. When the lifting door 130 descends, the lower part of the lifting door 130 may first contact the end of the shaft. The hydraulic buffer absorbs the impact force of the lifting door 130, and the shaft of the hydraulic buffer descends slowly, allowing the lower part of the lifting door 130 to slowly move to contact the bottom 113 to close the working space 117.

[0073] Understandably, there can be two buffers 330. The bottom 113 can be provided with two mounting slots, which are respectively connected to the first slide 1151 and the second slide 1153. A buffer 330 can be installed in each mounting slot, which helps to absorb the impact of the lifting door 130 when it descends from two positions, making the descent of the lifting door 130 smoother.

[0074] In some other embodiments, the buffer 330 may also employ a buffer structure such as a silicone pad or a rubber pad.

[0075] In some embodiments, the lifting door 130 may be provided with a handle for gripping, and the user can open or close the lifting door 130 by gripping the handle.

[0076] In the biological organoid 3D printer 100 provided in this application embodiment, by placing the air filter assembly 150 above the workspace 117 and opposite to the work platform 1131, the air filter assembly 150 is used to discharge air towards the work platform 1131. This allows the air filter assembly 150 to deliver clean airflow along the vertical Z direction towards the work platform 1131, forming an air curtain to reduce contamination of the liquid in the storage holes of the perforated plate placed on the work platform 1131 by microorganisms, dust, and other impurities, thus helping to improve the success rate of experiments. By setting the lifting door 130 to be movably connected to the side 115 along the vertical Z direction for opening or closing the workspace 117, compared to the side-rotating door opening and closing method in related technologies, the lifting door 130 in this application embodiment adopts a vertical Z-direction opening and closing method, which can better utilize the vertical Z-direction space of the biological organoid 3D printer 100, thereby reducing the horizontal space occupied by the biological organoid 3D printer 100 and meeting the user's needs.

[0077] The embodiments of the present invention have been described in detail above with reference to the accompanying drawings. However, the present invention is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes can be made without departing from the spirit of the present invention. Furthermore, the embodiments of the present invention and the features thereof can be combined with each other unless otherwise specified.

Claims

1. A bio-organoid 3D printer, characterized by, The application relates to a biological organ 3D printer. The body comprises a top, a bottom and a side connected between the top and the bottom, and a working space is formed between the top, the bottom and the side. The bottom is provided with a working platform, and the working space is located above the working platform. A lifting door is movably connected to the side in the vertical direction to open or close the working space. A filter assembly is connected to the top and / or the side, and the filter assembly is located above the working space and opposite to the working platform to blow air towards the working platform.

2. The bioreactor 3D printer of claim 1, wherein, The filter assembly comprises a filter part and an air outlet part, and the filter part and the air outlet part are both connected to the top and / or the side, and the filter part is opposite to the working platform. The air outlet part is located on the side of the filter part opposite to the working space to blow air towards the filter part.

3. The bioreactor 3D printer of claim 2, wherein, The filter assembly further comprises a mounting cover connected to the top and / or the side, and the mounting cover is provided with a containing cavity, and the filter part is arranged in the containing cavity. The containing cavity is provided with a top wall and a bottom wall opposite to each other in the vertical direction, the bottom wall is provided with a plurality of air passing holes, each air passing hole is communicated with the containing cavity and the working space, the top wall is provided with a mounting opening, and the air outlet part is connected to the mounting opening.

4. The bioreactor 3D printer of claim 1, wherein, The biological organ 3D printer further comprises a first guide rail and a first sliding block, the first guide rail is connected to the side and extends in the vertical direction. The first sliding block is slidably connected to the first guide rail, and the lifting door is connected to the first sliding block.

5. The bioreactor 3D printer of claim 4, wherein, The side of the side facing the working space is provided with a first sliding groove extending in the vertical direction, and the first guide rail and the first sliding block are arranged in the first sliding groove, and the lifting door is movably arranged in the first sliding groove in the vertical direction.

6. The bioreactor 3D printer of claim 4, wherein, The biological organ 3D printer further comprises a first roller, a counterweight and a connecting rope, and the first roller is connected to the side. The connecting rope is wound around the first roller, and two ends of the connecting rope are connected to the first sliding block and the counterweight respectively.

7. The bioreactor 3D printer of claim 6, wherein, The counterweight and the lifting door are equal in weight. And / or, the biological organ 3D printer further comprises a second roller, the first roller is arranged above the first guide rail, the second roller is located on the side away from the lifting door and connected to the side, and the connecting rope is wound around the second roller.

8. The bioreactor 3D printer of claim 4, wherein, The working space is located on one side of the side in a first horizontal direction, and the biological organ 3D printer further comprises a second guide rail and a second sliding block, the second guide rail is connected to the side and arranged opposite to the first guide rail in a second horizontal direction, and the first horizontal direction and the second horizontal direction are arranged at an angle. The second guide rail extends in the vertical direction, the second sliding block is slidably connected to the second guide rail, and the lifting door is connected to the second sliding block.

9. The bioreactor 3D printer of claim 1, wherein, The top is provided with a avoiding opening, the shape of the avoiding opening is matched with the shape of the lifting door, and the lifting door is movably arranged in the avoiding opening in the vertical direction.

10. The bioreactor 3D printer of claim 1, wherein, The bio-organ 3D printer further comprises a buffer connected to the bottom and located in the descending path of the lifting door.

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