Cooling electrophoresis tank for non-deformation gel electrophoresis

Abstract

The utility model relates to the field of electrophoresis tank cooling. The cooling electrophoresis tank comprises an inner tank, an outer tank, a water inlet pipe and a water outlet pipe, the inner tank comprises a hollow inner tank cavity, the outer tank comprises a hollow outer tank cavity, an outer tank protruding part is arranged on one side of the outer tank, an outer tank sunken clamping groove is formed in the outer tank protruding part, and the water inlet pipe is connected with the water outlet pipe. When the outer groove concave clamping groove abuts against the inner groove clamping part correspondingly, a heat conduction cavity is formed between the inner groove and the outer groove, and a plurality of heat dissipation fins used for increasing the heat dissipation area are arranged on one side of the outer groove. By integrating efficient heat dissipation design, a precise temperature control system and an intelligent operation interface, the temperature control precision in the electrophoresis process and the consistency of experimental results are remarkably improved. By means of the innovative design of the inner and outer groove structure, the optimized cooling liquid flowing path, the magnetic attraction connecting mechanism, heat insulation treatment and the like, the heat dissipation efficiency is greatly improved, the stability and uniformity of the temperature are ensured, the installation process is simplified, and the usability of the device is enhanced.

Description

Technical Field

[0001] This utility model relates to the field of electrophoresis tank cooling, and in particular to a cooling electrophoresis tank for nondeformable gel electrophoresis. Background Technology

[0002] Nondeformable gel electrophoresis (NDG) is a commonly used technique in molecular biology and proteomics research for the separation and analysis of protein or nucleic acid samples. During electrophoresis, the flow of current through the gel generates heat, causing a temperature rise that affects the accuracy and reproducibility of the results. Therefore, effective cooling measures are crucial for maintaining a constant electrophoresis environment. However, existing electrophoresis tank designs have several shortcomings in cooling. Traditional electrophoresis tanks typically rely on natural cooling or simple water cooling systems to lower the temperature, but these methods have low heat dissipation efficiency and cannot quickly and effectively remove the generated heat. Under prolonged operation or high voltage conditions, the internal temperature of the electrophoresis tank may rise significantly, affecting sample quality and the resolution of electrophoretic bands. Many existing electrophoresis tanks lack precise temperature control systems, resulting in large temperature fluctuations and making it difficult to maintain a constant operating temperature, affecting the consistency and reliability of experimental results. Temperature changes may cause gel shrinkage or expansion, affecting sample migration speed and separation efficiency. Existing electrophoresis tanks have low heat exchange efficiency between the inner and outer tanks, with long heat conduction paths, increasing heat transfer time and loss. Inadequate coolant flow path design can easily cause localized overcooling or overheating, affecting the overall cooling effect. For experiments requiring extremely low-temperature environments, such as those using liquid nitrogen as a cooling medium, existing electrophoresis tank designs often fail to adequately consider thermal insulation, leading to external environmental impact from the low temperature and increasing operational difficulty and safety hazards. The unreasonable placement of the cooling system's inlet and outlet pipes results in complex piping layouts, increasing installation and maintenance complexity. Furthermore, the lack of an intuitive user interface and intelligent control system makes it difficult for users to monitor and adjust temperature parameters during the electrophoresis process in real time. Utility Model Content

[0003] To address the shortcomings of existing technologies, this utility model discloses a cooling electrophoresis tank for nondeformable gel electrophoresis that is efficient, stable, and easy to operate, effectively solving the aforementioned problems.

[0004] This utility model discloses a cooling electrophoresis tank for nondeformable gel electrophoresis, which includes an inner tank, an outer tank, an inlet pipe, and an outlet pipe. The inner tank includes a hollow inner tank cavity, and an outwardly protruding inner tank limiting part is provided on one side of the inner tank. An inner tank protrusion is also provided on one side of the inner tank, and an inner tank locking part is provided on the inner tank protrusion. The outer tank includes a hollow outer tank cavity, and an inwardly recessed outer tank locking groove is provided on one side of the outer tank cavity to cooperate with the inner tank limiting part. An outer tank protrusion is also provided on one side of the outer tank. An inwardly recessed outer tank locking groove is provided on the side of the outer tank protrusion near the upper part to correspond to the inner tank locking part. When the outer tank locking groove and the inner tank locking part abut and correspond, a heat-conducting cavity is formed between the inner tank and the outer tank. The inlet pipe is provided through one side of the outer tank, and the outlet pipe is provided through one side of the outer tank. Several heat dissipation fins for increasing the heat dissipation area are provided on one side of the outer tank.

[0005] Furthermore, the heat dissipation fins are of different lengths, and these heat dissipation fins of different lengths are arranged at intervals.

[0006] Furthermore, the heat dissipation fins are provided with several outwardly protruding heat dissipation protrusions.

[0007] Furthermore, the water inlet pipe is located on one side of the outer tank, and the water outlet pipe is located on the other side of the outer tank away from the water inlet pipe. The water inlet pipe is located on the side of the outer tank near the bottom, and the water outlet pipe is located on the side of the outer tank near the top.

[0008] Furthermore, the exterior of the outer tank is insulated.

[0009] Furthermore, sealing gaskets are provided on the inner groove snap-fit ​​part and the outer groove recessed snap-fit ​​groove respectively.

[0010] Furthermore, an inner groove electromagnetic part is provided on the side of the inner groove protrusion near the outer groove, and an outer groove electromagnetic part is provided on the side of the outer groove protrusion near the inner side for magnetic attraction with the inner groove electromagnetic part.

[0011] The beneficial effects of this utility model are:

[0012] The cooled electrophoresis tank for nondeformable gel electrophoresis significantly improves temperature control accuracy and experimental result consistency during electrophoresis by integrating a highly efficient heat dissipation design, a precise temperature control system, and an intelligent operating interface. Its unique inner and outer tank structure, optimized coolant flow path, magnetic connection mechanism, and thermal insulation not only greatly improve heat dissipation efficiency, ensuring temperature stability and uniformity, but also simplify installation and maintenance processes, enhancing equipment safety and ease of use. Especially for experiments requiring extremely low temperatures, this electrophoresis tank effectively prevents cold loss and the influence of low temperatures on the external environment, providing more reliable operating conditions. Overall, this cooled electrophoresis tank provides an efficient, stable, and easy-to-manage tool for molecular biology and proteomics research, ensuring high-quality sample separation and analysis results. Attached Figure Description

[0013] Figure 1 This is a schematic diagram of a cooling electrophoresis tank in one embodiment of this application.

[0014] Figure 2 This is a schematic diagram of another structure of the cooling electrophoresis tank in the embodiments of this application.

[0015] In the figure: cooling electrophoresis tank 100, inner tank 11, inner tank limiting part 111, inner tank protrusion 112, inner tank snap-fit ​​part 113, inner tank electromagnetic part 114, outer tank 12, outer tank protrusion 121, outer tank electromagnetic part 122, water inlet pipe 13, water outlet pipe 14, heat dissipation fins 15, heat dissipation protrusion 151. Detailed Implementation

[0016] To enable those skilled in the art to better understand the present invention, the technical solutions in the specific embodiments of the present invention will be clearly and completely described below.

[0017] This utility model discloses a cooled electrophoresis tank 100 for non-deformable gel electrophoresis, such as... Figure 1As shown, it includes an inner tank 11, an outer tank 12, an inlet pipe 13, and an outlet pipe 14. The inner tank 11 includes a hollow inner tank cavity. An outwardly protruding inner tank limiting part 111 is provided on one side of the inner tank 11. An inner tank protrusion 112 protrudes outward from one side of the inner tank 11. An inner tank engaging part 113 protrudes downward from the inner tank protrusion 112. The outer tank 12 includes a hollow outer tank cavity. An inwardly recessed outer tank groove is provided on one side of the outer tank cavity to cooperate with the inner tank limiting part 111. One side of the inner tank 11 has an outwardly protruding outer groove protrusion 121. Near the upper part of the outer groove protrusion 121, there is an inwardly recessed groove corresponding to the inner groove engaging part 113. When the outer groove engages with the inner groove engaging part 113, a heat-conducting cavity is formed between the inner groove 11 and the outer groove 12. An inlet pipe 13 and an outlet pipe 14 are both provided through one side of the outer groove 12. Several heat dissipation fins 15 are provided on one side of the outer groove 12 to increase the heat dissipation area. The heat-conducting cavity formed between the inner groove 11 and the outer groove 12, along with the heat dissipation fins 15 on one side of the outer groove 12, significantly increases the heat dissipation area and effectively improves heat dissipation efficiency. This helps maintain a stable gel temperature during electrophoresis, preventing gel deformation or sample diffusion due to temperature increases, thus ensuring the accuracy of the electrophoresis results. The design of the inlet pipe 13 and the outlet pipe 14 allows the coolant to circulate, and precise control of the internal temperature of the electrophoresis tank can be achieved by adjusting the flow rate and temperature of the coolant. This design is particularly important for experiments requiring strict temperature conditions, ensuring reproducibility between different batches. The mating design of the inner tank limiting part 111 with the outer tank slot, and the inner tank engaging part 113 with the outer tank recessed slot, not only achieves a stable connection between the inner and outer tanks 12, but also forms a closed heat-conducting cavity, enhancing the mechanical stability of the entire device. Simultaneously, this modular design facilitates disassembly and maintenance. Through effective temperature management and heat dissipation mechanisms, this electrophoresis tank can maintain a low and constant temperature environment, avoiding the gel deformation problems caused by temperature changes common in traditional electrophoresis tanks, making it particularly suitable for applications of non-deformable gel electrophoresis. The automated cooling system reduces the need for manual intervention, making the electrophoresis process smoother and faster, shortening experimental time, and improving work efficiency. Furthermore, stable temperature conditions also help reduce experimental errors and improve data reliability.

[0018] In one implementation, several heat dissipation fins 15 are arranged at varying lengths. The heat dissipation fins 15 of different lengths can cover a larger surface area as needed, thus significantly increasing the total heat dissipation area and improving overall heat dissipation efficiency. The alternating arrangement of long and short heat dissipation fins 15 helps to create a more uniform temperature field around the electrophoresis tank, avoiding localized overheating and ensuring a consistent temperature throughout the gel region. The varying lengths of the heat dissipation fins 15 can guide the coolant to form more complex flow paths, increasing turbulence and promoting rapid heat transfer to the coolant, further improving heat dissipation performance. A reasonable length-to-length interval design can reduce coolant flow resistance while ensuring sufficient heat dissipation area, allowing for smoother coolant circulation and reducing pumping energy consumption. By rationally arranging the length and spacing of the heat dissipation fins 15, maximum heat dissipation can be achieved within a limited space, making the electrophoresis tank design more compact and saving laboratory space. The use of heat dissipation fins 15 of different lengths and arranged according to the length interval significantly improves the functionality and practicality of the cooling electrophoresis tank 100. It not only optimizes the heat dissipation effect and fluid flow characteristics, but also enhances the stability and durability of the equipment, providing users with an efficient, reliable and environmentally friendly experimental tool.

[0019] In one implementation, the heat dissipation fins 15 are provided with a plurality of outwardly protruding heat dissipation protrusions 151. The presence of the heat dissipation protrusions 151 greatly increases the effective heat dissipation surface area of ​​the heat dissipation fins 15, allowing more heat to be conducted from the electrophoresis tank to the air or coolant, thereby significantly improving the overall heat dissipation efficiency. The heat dissipation protrusions 151 can disrupt the flow path of the air or coolant, promoting the formation of more complex turbulence and enhancing the heat transfer effect. The turbulence effect helps to break the boundary layer, reduce thermal resistance, and further improve heat dissipation performance. The heat dissipation protrusions 151 can help guide the coolant to form a more uniform flow pattern, avoiding local flow stagnation or dead zones, ensuring a more consistent temperature throughout the heat dissipation area, and reducing the risk of local overheating. The design of the heat dissipation protrusions 151 not only increases the mechanical strength of the heat dissipation fins 15, but also disperses external stress, preventing deformation or damage caused by excessive force at a single point, and enhancing the stability and durability of the overall structure. The heat dissipation protrusion 151 can adapt to the thermal expansion and contraction caused by temperature changes through its own slight deformation, which alleviates the stress accumulation inside the material and extends the service life of the heat dissipation fins 15.

[0020] In one implementation, the inlet pipe 13 is located on one side of the outer tank 12, and the outlet pipe 14 is located on the other side of the outer tank 12 away from the inlet pipe 13. The inlet pipe 13 is located on the side of the outer tank 12 near the bottom, and the outlet pipe 14 is located on the side of the outer tank 12 near the top. The design of the coolant entering from the bottom and exiting from the top ensures that the coolant forms an upward flow path throughout the entire outer tank 12. This helps to evenly distribute the coolant, covering the entire heat-conducting cavity area, thereby improving overall cooling efficiency. Since the coolant temperature is lower at the bottom, it gradually absorbs heat and heats up during its ascent, forming a natural convection effect. This design fully utilizes the natural convection caused by temperature differences, enhancing the cooling effect. The coolant entering from the bottom effectively reduces the generation of air bubbles, and any bubbles that may form are carried out of the system during the ascent, preventing bubbles from accumulating in the heat-conducting cavity and affecting heat dissipation. The bottom-to-top flow path increases the contact time between the coolant and the wall of the outer tank 12, allowing the coolant to absorb heat more fully, improving coolant utilization, and reducing coolant demand and pumping energy consumption.

[0021] As one implementation, the exterior of the outer tank 12 is thermally insulated. This insulation effectively reduces heat exchange between the interior of the outer tank 12 and the external environment, preventing heat loss and ensuring that the energy of the cooling medium, such as liquid nitrogen, can be used more effectively for cooling, thus improving overall cooling efficiency. The insulation layer helps maintain a stable internal temperature of the electrophoresis tank, avoiding temperature changes caused by external temperature fluctuations, ensuring the consistency and reliability of temperature conditions during experiments, and improving the accuracy of experimental results. In low-temperature environments, uninsulated outer surfaces are prone to condensation, which may damage the equipment and its surrounding environment. Thermal insulation effectively prevents condensation formation, protecting the electrophoresis tank and other laboratory equipment from moisture corrosion. When using liquid nitrogen, direct contact with extremely cold surfaces may cause frostbite. Thermal insulation effectively prevents accidental contact with excessively cold outer surfaces, improving the safety of experimental operations.

[0022] As one implementation, sealing gaskets are respectively provided on the inner tank snap-fit ​​portion 113 and the outer tank recessed slot. The presence of the sealing gaskets can effectively prevent coolant or cold air from leaking from the connection between the inner tank 11 and the outer tank 12, ensuring the integrity of the cooling system. This is especially important when using cryogenic cooling media such as liquid nitrogen, as any leakage may lead to temperature control failure or safety hazards. The sealing gaskets help to further reduce heat exchange between the inner and outer tanks 12 and the external environment, maintaining the stability and consistency of the internal temperature of the electrophoresis tank, thereby improving the accuracy and repeatability of experimental results. The sealing gaskets can prevent coolant or other chemicals from seeping into the equipment, avoiding corrosion or damage to mechanical parts or electronic components, and extending the service life of the equipment. The design of the sealing gaskets makes the connection between the inner tank 11 and the outer tank 12 tighter and smoother, simplifying the assembly process and reducing sealing problems caused by improper assembly. At the same time, it also facilitates daily maintenance and cleaning.

[0023] As one implementation method, such as Figure 2 As shown, an inner groove electromagnetic part 114 is provided on the side of the inner groove protrusion 112 near the outer groove 12, and an outer groove electromagnetic part 122 is provided on the side of the outer groove protrusion 121 near the inner side for magnetic attraction with the inner groove electromagnetic part 114. The magnetic attraction between the electromagnetic parts ensures that the inner groove 11 and the outer groove 12 can be automatically aligned during installation, reducing the need for manual adjustment and improving assembly accuracy. This is especially important for applications requiring strict positional matching. The electromagnetic attraction makes the installation and removal of the inner groove 11 and the outer groove simple and quick, without the need for complicated tools or fasteners, greatly simplifying the operation process and saving time and labor. The magnetic force provided by the electromagnetic part can provide a stable connection without increasing mechanical stress, avoiding the loosening or falling off problems that may occur with traditional fixing methods, and enhancing the stability of the overall structure.

[0024] It should be understood that those skilled in the art can make improvements or modifications based on the above description, and all such improvements and modifications should fall within the protection scope of the appended claims.

Claims

1. A cooled electrophoresis tank for nondeformable gel electrophoresis, characterized in that, include: The inner groove includes a hollow inner groove cavity. An outwardly protruding inner groove limiting part is provided on one side of the inner groove. An inner groove protrusion is also provided on one side of the inner groove. An inner groove snap-fit ​​part is provided on the inner groove protrusion. The outer groove includes a hollow outer groove cavity. One side of the outer groove cavity is provided with an inwardly recessed outer groove that cooperates with the inner groove limiting part. One side of the outer groove has an outwardly protruding outer groove protrusion. On the side of the outer groove protrusion near the upper part, there is an inwardly recessed outer groove corresponding to the inner groove engaging part. When the outer groove recessed outer groove and the inner groove engaging part abut and correspond, a heat-conducting cavity is formed between the inner groove and the outer groove. The water inlet pipe is installed on one side of the outer tank. The water outlet pipe runs through one side of the outer tank; One side of the outer slot is provided with several heat dissipation fins to increase the heat dissipation area.

2. A cooled electrophoresis tank for nondeformable gel electrophoresis according to claim 1, characterized in that: Several heat dissipation fins of different lengths are arranged at intervals according to their lengths.

3. A cooled electrophoresis tank for nondeformable gel electrophoresis according to claim 1, characterized in that: The heat dissipation fins are provided with several outward-protruding heat dissipation protrusions.

4. A cooled electrophoresis tank for nondeformable gel electrophoresis according to claim 1, characterized in that: The water inlet pipe is located on one side of the outer tank, and the water outlet pipe is located on the other side of the outer tank away from the water inlet pipe; The inlet pipe is located on the side of the outer tank near the bottom, and the outlet pipe is located on the side of the outer tank near the top.

5. A cooled electrophoresis tank for nondeformable gel electrophoresis according to claim 1, characterized in that: The exterior of the outer tank is insulated.

6. A cooled electrophoresis tank for nondeformable gel electrophoresis according to claim 1, characterized in that: Sealing gaskets are provided on the inner groove snap-fit ​​part and the outer groove recessed snap-fit ​​groove respectively.

7. A cooled electrophoresis tank for nondeformable gel electrophoresis according to claim 1, characterized in that: An inner groove electromagnetic part is provided on the side of the inner groove protrusion near the outer groove, and an outer groove electromagnetic part is provided on the side of the outer groove protrusion near the inner side for magnetic attraction with the inner groove electromagnetic part.

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