Raw material cleaning device for polypeptide preparation

Abstract

The utility model relates to the technical field of polypeptide processing, and discloses a raw material cleaning device for polypeptide preparation, which comprises a mounting shell, a feed pipe is fixedly connected to the top of the mounting shell, a discharge pipe is fixedly connected to the bottom of the mounting shell, and a filter component and a positioning component are mounted on the mounting shell. The second motor can drive the positioning frame to move upwards and release pressing and positioning of the filter membrane, in the process that the first motor drives the second roller to rotate, the old filter membrane located at the top of the supporting plate is wound around the surface of the second roller, and the new filter membrane wound around the surface of the first roller moves to the top of the supporting plate; according to the filter membrane replacement device, the filter membrane replacement work can be rapidly completed, manual operation is not needed in the whole filter membrane replacement process, the automation degree is extremely high, and in addition, the stability of the filter membrane can be guaranteed through the pressing and positioning effects of the positioning frame on the filter membrane.

Description

Technical Field

[0001] This utility model relates to the field of polypeptide processing technology, and more specifically to a raw material cleaning device for polypeptide production. Background Technology

[0002] In the preparation and processing of peptides, in order to improve the purity of peptides, the raw materials used for peptide preparation need to be cleaned. During the cleaning process, the staff will dissolve the peptide raw materials as solutes in an appropriate solvent, mix them to form a solution, and then pass the solution through a filter membrane to remove insoluble impurities and macromolecular substances mixed in the raw materials.

[0003] Currently, when replacing filter membranes, since the filter membranes are usually installed inside the housing of the filtration equipment, the staff needs to manually disassemble the housing in order to remove the filter membrane for replacement, which is a rather cumbersome process. Utility Model Content

[0004] In order to overcome the above-mentioned defects of the prior art, the present invention provides a raw material cleaning device for polypeptide production, so as to solve the problems existing in the background art.

[0005] This utility model provides the following technical solution: a raw material cleaning device for polypeptide production, including a mounting shell, a feed pipe fixedly connected to the top of the mounting shell, a discharge pipe fixedly connected to the bottom of the mounting shell, and a filter assembly and a positioning assembly installed on the mounting shell.

[0006] The filtration assembly includes a first roller, a second roller, and a first motor. A filter membrane is wound around the surface of the first roller. One end of the filter membrane is fixedly connected to the surface of the first roller, and the other end of the filter membrane is fixedly connected to the surface of the second roller. The first motor is used to drive the second roller to rotate.

[0007] Preferably, a fixing block is fixedly connected to both the left and right sides of the mounting shell, a mounting rod is rotatably connected to the center of the first roller, and the mounting rod is fixedly installed on the fixing block, and a rotating rod is fixedly connected to the center of the second roller, and the rotating rod is rotatably installed on the fixing block.

[0008] Preferably, a mounting bracket is fixedly mounted on the surface of the mounting shell, the first motor is fixedly mounted on the top of the mounting bracket, a worm gear is fixedly mounted on the output end of the first motor, and a worm wheel is fixedly mounted on one end of the rotating rod, with the worm gear and the worm wheel meshing together.

[0009] Preferably, the mounting shell has through openings on both the left and right sides, a support plate is fixedly connected inside the mounting shell, the filter membrane is located on top of the support plate, and the filter membrane passes through the through openings.

[0010] Preferably, the positioning component includes a positioning frame located on top of the filter membrane, a receiving frame fixedly connected to the surface of the positioning frame, an avoidance hole extending through the rear side of the mounting shell, the receiving frame passing through the avoidance hole, and a second motor fixedly mounted on the top of the receiving frame.

[0011] Preferably, a stabilizing frame and a connecting frame are fixedly installed on the rear side of the mounting housing. A guide rod is fixedly connected to the stabilizing frame, and multiple guide rods are evenly arranged. A rack is fixedly connected to the connecting frame. The receiving frame is sleeved on the surface of the guide rod. A gear is fixedly connected to the output end of the second motor, and the gear meshes with the rack.

[0012] The technical effects and advantages of this utility model are as follows:

[0013] When the filter membrane used for filtering peptide raw materials needs to be replaced, the second motor can drive the positioning frame to move upward and release the clamping and positioning of the filter membrane. The first motor drives the second roller to rotate around the axis of the rotating rod. During the rotation of the second roller, the old filter membrane located at the top of the support plate is wound up and wrapped around the surface of the second roller, while the new filter membrane wrapped around the surface of the first roller moves to the top of the support plate. The second motor then reverses to make the positioning frame move downward, and the new filter membrane is clamped and positioned on the top of the support plate. This utility model can quickly complete the filter membrane replacement work, and the entire filter membrane replacement process does not require manual operation and has a high degree of automation. In addition, the clamping and positioning of the filter membrane by the positioning frame can ensure the stability of the filter membrane. Attached Figure Description

[0014] Figure 1 This is a schematic diagram of the overall structure of this utility model.

[0015] Figure 2 This is a schematic diagram of the overall structure of this utility model.

[0016] Figure 3 This is a cross-sectional view of the overall structure of this utility model.

[0017] Figure 4 This is a cross-sectional view of the mounting shell of this utility model.

[0018] Figure 5 This is a schematic diagram of the filter assembly structure of this utility model.

[0019] Figure 6 This is a schematic diagram of the positioning component structure of this utility model.

[0020] The attached figures are labeled as follows: 1. Mounting shell; 11. Support plate; 12. Through-hole; 13. Clearance hole; 14. Fixing block; 2. Feed pipe; 3. Discharge pipe; 4. Filter assembly; 41. First roller; 42. Second roller; 43. Mounting rod; 44. Rotating rod; 45. Filter membrane; 46. Fixing frame; 47. First motor; 48. Worm gear; 49. Worm wheel; 5. Positioning assembly; 51. Positioning frame; 52. Receiving frame; 53. Stabilizing frame; 54. Second motor; 55. Connecting frame; 56. Gear; 57. Rack; 58. Guide rod. Detailed Implementation

[0021] The technical solution of this utility model will be clearly and completely described below with reference to the accompanying drawings. In addition, the morphology of each structure described in the following embodiments is merely illustrative. The raw material cleaning device for polypeptide production involved in this utility model is not limited to the structures described in the following embodiments. All other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.

[0022] This utility model provides a raw material cleaning device for polypeptide production, including a mounting shell 1, a feed pipe 2 fixedly connected to the top of the mounting shell 1, a discharge pipe 3 fixedly connected to the bottom of the mounting shell 1, and a filter assembly 4 and a positioning assembly 5 installed on the mounting shell 1.

[0023] The filter assembly 4 includes a first roller 41, a second roller 42, and a first motor 47. A filter membrane 45 is wound around the surface of the first roller 41. One end of the filter membrane 45 is fixedly connected to the surface of the first roller 41, and the other end of the filter membrane 45 is fixedly connected to the surface of the second roller 42. The first motor 47 is used to pull the second roller 42 to rotate.

[0024] Furthermore, fixing blocks 14 are fixedly connected to both sides of the mounting shell 1. A mounting rod 43 is rotatably connected to the center of the first roller 41 and is fixedly mounted on the fixing block 14. A rotating rod 44 is fixedly connected to the center of the second roller 42 and is rotatably mounted on the fixing block 14. A fixing frame 46 is fixedly mounted on the surface of the mounting shell 1. A first motor 47 is fixedly mounted on the top of the fixing frame 46. A worm gear 48 is fixedly mounted on the output end of the first motor 47. A worm wheel 49 is fixedly mounted on one end of the rotating rod 44. The worm gear 48 and the worm wheel 49 are meshed and connected. The worm gear 48 and the worm wheel 49 cooperate to convert the output power of the first motor 47 into the rotational force of the rotating rod 44. The rotational force of the rotating rod 44 can pull the second roller 42 to rotate around the axis of the rotating rod 44. During the rotation of the second roller 42, the old filter membrane 45 located on the top of the support plate 11 is wound up and wrapped to the surface of the second roller 42, while the new filter membrane 45 wrapped on the surface of the first roller 41 moves to the top of the support plate 11.

[0025] Furthermore, the mounting shell 1 has through openings 12 on both the left and right sides, and a support plate 11 is fixedly connected inside the mounting shell 1. The filter membrane 45 is located on the top of the support plate 11 and passes through the through openings 12.

[0026] Furthermore, the positioning component 5 includes a positioning frame 51, which is located on top of the filter membrane 45 and is used to press and position the filter membrane 45. A receiving frame 52 is fixedly connected to the surface of the positioning frame 51. An avoidance hole 13 is provided through the rear side of the mounting shell 1, through which the receiving frame 52 passes. A second motor 54 is fixedly installed on the top of the receiving frame 52. A stabilizing frame 53 and a connecting frame 55 are fixedly installed on the rear side of the mounting shell 1. A guide rod 58 is fixedly connected to the stabilizing frame 53, and multiple guide rods 58 are evenly arranged. A connecting frame 55 is fixedly connected to... A rack 57 is connected, and a support frame 52 is sleeved on the surface of the guide rod 58. The support frame 52 and the guide rod 58 form a sliding guide fit along the axis of the guide rod 58. A gear 56 is fixedly connected to the output end of the second motor 54. The gear 56 meshes with the rack 57. The second motor 54 can drive the gear 56 to rotate around its own axis. While the gear 56 rotates, it can move synchronously along the length of the rack 57. The second motor 54 is a stepper motor. The stepper motor has a self-locking function, which can ensure that the positioning frame 51 can be fixed in any position.

[0027] The working principle of this utility model is as follows: the polypeptide raw material is dissolved in the solvent as a solute and mixed to form a solution. Then the solution is input into the mounting shell 1 through the feed pipe 2. During this process, the solution passes through the filter membrane 45. The polypeptide raw material can pass through the filter membrane 45 smoothly, while insoluble impurities and macromolecules in the polypeptide raw material cannot pass through the filter membrane 45 and are intercepted. Finally, the polypeptide raw material is output to the outside through the discharge pipe 3.

[0028] When the filter membrane 45 needs to be replaced, the second motor 54 drives the gear 56 to rotate around its own axis. While the gear 56 rotates, it moves upward synchronously along the rack 57. The receiving frame 52 slides upward synchronously along the guide rod 58. The positioning frame 51 moves upward synchronously and releases the pressure and positioning of the filter membrane 45. The first motor 47 drives the rotating rod 44 to rotate around its own axis through the worm 48 and worm wheel 49. The rotating rod 44 rotates and drives the second roller 42 to rotate synchronously around the axis of the rotating rod 44. During the rotation of the second roller 42, the old filter membrane 45 located at the top of the support plate 11 is wound up and wrapped around the surface of the second roller 42, while the new filter membrane 45 wrapped around the surface of the first roller 41 moves to the top of the support plate 11. At this time, the second motor 54 rotates in the opposite direction. Similarly, the positioning frame 51 moves downward to press and position the new filter membrane 45 on the top of the support plate 11, completing the replacement of the filter membrane 45.

[0029] Finally, the following points should be noted: First, in the description of this application, it should be noted that, unless otherwise specified and limited, the terms "installation", "connection", and "linkage" should be interpreted broadly, and can be mechanical or electrical connections, or internal connections between two components, or direct connections. "Up", "down", "left", "right", etc. are only used to indicate relative positional relationships. When the absolute position of the described object changes, the relative positional relationship may change.

[0030] Secondly: The accompanying drawings of the embodiments disclosed in this utility model only involve the structures involved in the embodiments disclosed in this utility model. Other structures can refer to the general design. In the absence of conflict, the same embodiment and different embodiments of this utility model can be combined with each other.

[0031] Finally: The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A raw material cleaning device for polypeptide production, comprising a mounting shell (1), characterized in that, The top of the mounting shell (1) is fixedly connected to a feed pipe (2), the bottom of the mounting shell (1) is fixedly connected to a discharge pipe (3), and a filter assembly (4) and a positioning assembly (5) are installed on the mounting shell (1). The filter assembly (4) includes a first roller (41), a second roller (42) and a first motor (47). A filter membrane (45) is wound around the surface of the first roller (41). One end of the filter membrane (45) is fixedly connected to the surface of the first roller (41), and the other end of the filter membrane (45) is fixedly connected to the surface of the second roller (42). The first motor (47) is used to pull the second roller (42) to rotate.

2. The raw material cleaning device for polypeptide production according to claim 1, characterized in that, The mounting shell (1) is fixedly connected to the left and right sides of the mounting block (14). The first roller (41) is rotatably connected to the center of the mounting rod (43), which is fixedly installed on the mounting block (14). The second roller (42) is fixedly connected to the center of the mounting rod (44), which is rotatably installed on the mounting block (14).

3. The raw material cleaning device for polypeptide production according to claim 2, characterized in that, A mounting bracket (46) is fixedly mounted on the surface of the mounting shell (1). The first motor (47) is fixedly mounted on the top of the mounting bracket (46). A worm gear (48) is fixedly mounted on the output end of the first motor (47). A worm wheel (49) is fixedly mounted on one end of the rotating rod (44). The worm gear (48) and the worm wheel (49) are meshed and connected.

4. The raw material cleaning device for polypeptide production according to claim 3, characterized in that, The mounting shell (1) has through openings (12) on both the left and right sides. A support plate (11) is fixedly connected inside the mounting shell (1). The filter membrane (45) is located on top of the support plate (11) and passes through the through openings (12).

5. The raw material cleaning device for polypeptide production according to claim 4, characterized in that, The positioning component (5) includes a positioning frame (51), which is located on top of the filter membrane (45). A receiving frame (52) is fixedly connected to the surface of the positioning frame (51). A clearance hole (13) is provided through the rear side of the mounting shell (1). The receiving frame (52) passes through the clearance hole (13). A second motor (54) is fixedly installed on the top of the receiving frame (52).

6. The raw material cleaning device for polypeptide production according to claim 5, characterized in that, A stabilizing frame (53) and a connecting frame (55) are fixedly installed on the rear side of the mounting shell (1). A guide rod (58) is fixedly connected to the stabilizing frame (53). Multiple guide rods (58) are evenly arranged. A rack (57) is fixedly connected to the connecting frame (55). A receiving frame (52) is sleeved on the surface of the guide rod (58). A gear (56) is fixedly connected to the output end of the second motor (54). The gear (56) meshes with the rack (57).

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