Fermentation kettle for hydroxyproline production

Abstract

The utility model relates to the technical field of chemical machinery, in particular to a fermentation kettle for hydroxyproline production, which can add a carbon source into a fermentation tank in the fermentation process, and is convenient to use, low in limitation and high in practicability. Comprising a bottom plate, a support, a fermentation tank and a feeding pipe, the fermentation tank is fixedly installed at the upper end of the bottom plate through the support, a cavity is formed in the fermentation tank, the feeding pipe is arranged on the upper portion of the fermentation tank, a discharging pipe is arranged on the lower portion of the fermentation tank, and a valve is arranged on the discharging pipe; the device further comprises a stirring mechanism and a carbon source adding mechanism, the stirring mechanism is mounted on the fermentation tank and has a stirring function, and the carbon source adding mechanism is communicated with the fermentation tank and used for adding a carbon source into the fermentation tank.

Description

Technical Field

[0001] This utility model relates to the technical field of chemical machinery, and in particular to a fermentation vessel for the production of hydroxyproline. Background Technology

[0002] Hydroxyproline is an imino acid, a non-essential amino acid, and a major component of collagen tissue, with important applications in medicine. Microbial fermentation is a commonly used method for producing hydroxyproline. During production, microbial inoculum is added to a fermenter to contact with the fermentation broth, and a carbon source is added during fermentation. After fermentation, the fermentation product is separated and purified to obtain hydroxyproline. In the prior art, utility model patent application number 202420384278.2 discloses a hydroxyproline production fermentation device, mainly composed of a fermenter and a stirring mechanism. In use, microorganisms are added to the fermenter to contact with the fermentation broth, and the fermentation reaction proceeds. However, this device has the following problem: to ensure the fermentation rate, a carbon source, such as glucose solution, needs to be added to the fermenter periodically during fermentation. However, the aforementioned prior art fermentation device does not have a dedicated mechanism for adding the carbon source, making it inconvenient to use and impractical. Utility Model Content

[0003] To solve the above-mentioned technical problems, this utility model provides a fermentation vessel for the production of hydroxyproline that allows the addition of a carbon source to the fermenter during the fermentation process, is easy to use, has low limitations, and is highly practical.

[0004] This invention relates to a fermentation vessel for the production of hydroxyproline, comprising a base plate, a support frame, a fermentation tank, and a feeding pipe. The fermentation tank is fixedly mounted on the upper end of the base plate via the support frame. The fermentation tank contains a chamber, with a feeding pipe at the top and a discharge pipe at the bottom, equipped with a valve. It also includes a stirring mechanism and a carbon source adding mechanism. The stirring mechanism is mounted on the fermentation tank and functions as a stirring device. The carbon source adding mechanism is connected to the fermentation tank and is used to add a carbon source to the fermentation tank. During hydroxyproline production, when fermentation is required, fermentation broth is first added to the fermentation tank, followed by the addition of microorganisms. The stirring mechanism is then activated to ensure uniform mixing of the microorganisms and fermentation broth, promoting contact between the microorganisms and the broth and facilitating fermentation. During fermentation, when carbon source needs to be added to the fermentation broth, the carbon source adding mechanism is activated to add carbon source, thereby improving the fermentation efficiency of the microorganisms. This invention allows for the addition of carbon source during fermentation, is convenient to use, has low limitations, and is highly practical.

[0005] Preferably, the stirring mechanism includes two sets of rotating shafts, multiple sets of stirring blades, a motor, and a transmission mechanism. The two sets of rotating shafts are rotatably installed on the left and right sides of the fermentation tank, respectively, with both the upper and lower ends of the two sets of rotating shafts located on the outside of the fermentation tank. Multiple sets of stirring blades are installed on each set of rotating shafts, and the multiple sets of stirring blades are located inside the chamber of the fermentation tank. The two sets of rotating shafts are connected by a transmission mechanism. The motor is installed at the upper end of the fermentation tank, and the output end of the motor is connected to one of the sets of rotating shafts. When stirring the fermentation liquid inside the fermentation tank chamber, the motor is turned on, and the motor drives one set of rotating shafts to rotate, which in turn drives the other set of rotating shafts to rotate through the transmission mechanism, so that the two sets of rotating shafts rotate simultaneously, thereby driving the multiple sets of stirring blades to rotate, promoting the movement of the fermentation liquid inside the fermentation tank chamber, and promoting the contact between microorganisms and the fermentation liquid.

[0006] Preferably, the transmission mechanism includes sprocket A, sprocket B, and a chain. Sprocket A and sprocket B are respectively installed at the lower ends of two sets of rotating shafts, and sprocket A and sprocket B are connected by chain transmission. When one set of rotating shafts rotates, the rotating shaft drives sprocket B to rotate through sprocket A and the chain, thereby causing the other set of rotating shafts to rotate, so that the two sets of rotating shafts rotate synchronously, which promotes the contact between the fermentation broth and microorganisms.

[0007] Preferably, the carbon source addition mechanism includes a storage tank, a delivery pump, a delivery hose, a discharge pipe, and a lifting mechanism. The storage tank is mounted on a base plate, and the delivery pump is also mounted on the base plate. The input end of the delivery pump is connected to the storage tank, and the output end of the delivery pump is connected to the discharge pipe via the delivery hose. The discharge pipe is located within the chamber of the fermenter and is mounted on the lifting mechanism, which is used to raise and lower the discharge pipe. The storage tank stores glucose solution. When it is necessary to add a carbon source to the fermenter to promote the reaction, the delivery pump is turned on, allowing the carbon source in the storage tank to enter the chamber of the fermenter sequentially via the delivery pump, the delivery hose, and the discharge pipe, thus facilitating the addition of a carbon source to the fermenter.

[0008] Preferably, the lifting mechanism includes a hydraulic cylinder, a push rod, and a fixing plate. The hydraulic cylinder is fixedly installed at the upper end of the fermentation tank, and the push rod is slidably installed on the fermentation tank. The upper end of the push rod is connected to the output end of the hydraulic cylinder, and the discharge pipe is fixedly installed at the lower end of the push rod through the fixing plate. When carbon source is added to the chamber of the fermentation tank through the discharge pipe, the hydraulic cylinder is opened. The hydraulic cylinder, through the push rod, causes the fixing plate to drive the discharge pipe to adjust its height, so that the discharge pipe moves up and down during the discharge of carbon source, so that the carbon source is evenly discharged at different heights in the fermentation liquid, and the carbon source can be evenly distributed in the fermentation liquid, improving convenience.

[0009] Preferably, the upper part of the fermenter is provided with multiple sets of vent pipes, and each set of vent pipes is provided with a breathable sterilization membrane; the above configuration facilitates the ventilation of the fermenter.

[0010] Preferably, the fermenter is equipped with a thermometer; this facilitates the monitoring of the temperature inside the fermenter chamber.

[0011] Compared with the prior art, the advantages of this utility model are: carbon source can be added to the fermentation tank during the fermentation process, which is convenient to use, has low limitations, and is highly practical. Attached Figure Description

[0012] Figure 1 This is a schematic diagram of the first isometric structure of this utility model;

[0013] Figure 2 This is a schematic diagram of the second isometric structure of this utility model;

[0014] Figure 3 This is a cross-sectional structural schematic diagram of the present invention;

[0015] Figure 4 This is a schematic diagram of the stirring mechanism;

[0016] Figure 5 This is a schematic diagram of the carbon source addition mechanism.

[0017] The following are labels in the attached diagram: 1. Base plate; 2. Support frame; 3. Fermentation tank; 4. Feeding pipe; 5. Rotating shaft; 6. Stirring blade; 7. Motor; 8. Sprocket A; 9. Sprocket B; 10. Chain; 11. Storage tank; 12. Transfer pump; 13. Transfer hose; 14. Discharge pipe; 15. Hydraulic cylinder; 16. Push rod; 17. Fixing plate. Detailed Implementation

[0018] To facilitate understanding of this utility model, a more complete description will be given below with reference to the accompanying drawings. This utility model can be implemented in many different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided to make the disclosure of this utility model more thorough and complete.

[0019] Example 1

[0020] like Figures 1 to 5The fermentation vessel for hydroxyproline production of this invention includes a bottom plate 1, a support 2, a fermentation tank 3, a feeding pipe 4, a stirring mechanism, and a carbon source addition mechanism. The fermentation tank 3 is fixedly installed on the upper end of the bottom plate 1 via the support 2. The fermentation tank 3 has a chamber. The feeding pipe 4 is located at the upper part of the fermentation tank 3, and a discharge pipe with a valve is located at the lower part of the fermentation tank 3. The stirring mechanism is installed on the fermentation tank 3 and has a stirring function. The carbon source addition mechanism is connected to the fermentation tank 3 and is used to add a carbon source to the fermentation tank 3. In the production of hydroxyproline... When fermentation is required, first add fermentation broth to fermentation tank 3, then add microorganisms to fermentation tank 3, and then turn on the stirring mechanism to mix the microorganisms and fermentation broth evenly, promoting contact between the microorganisms and fermentation broth, allowing the microorganisms to ferment the broth. During the fermentation process, if it is necessary to add carbon source to the fermentation broth in fermentation tank 3, turn on the carbon source adding mechanism to add carbon source to the fermentation broth in fermentation tank 3, thus promoting the fermentation efficiency of microorganisms. It can add carbon source to fermentation tank 3 during the fermentation process, which is convenient to use, has low limitations, and is highly practical.

[0021] like Figure 3 and Figure 4 The stirring mechanism includes two sets of rotating shafts 5, multiple sets of stirring blades 6, a motor 7, and a transmission mechanism. The two sets of rotating shafts 5 are respectively rotatably installed on the left and right sides of the fermentation tank 3. The upper and lower ends of the two sets of rotating shafts 5 are located on the outside of the fermentation tank 3. Multiple sets of stirring blades 6 are installed on each set of rotating shafts 5, and the multiple sets of stirring blades 6 are located in the chamber of the fermentation tank 3. The two sets of rotating shafts 5 are connected by the transmission mechanism. The motor 7 is installed at the upper end of the fermentation tank 3, and the output end of the motor 7 is connected to one of the sets of rotating shafts 5. When stirring the fermentation liquid in the chamber of the fermentation tank 3, the motor 7 is turned on. The motor 7 drives one set of rotating shafts 5 to rotate, which in turn drives the other set of rotating shafts 5 to rotate through the transmission mechanism, so that the two sets of rotating shafts 5 rotate simultaneously, which in turn drives the multiple sets of stirring blades 6 to rotate, promoting the movement of the fermentation liquid in the chamber of the fermentation tank 3 and promoting the contact between microorganisms and the fermentation liquid.

[0022] like Figure 4 The transmission mechanism includes sprocket A8, sprocket B9, and chain 10. Sprocket A8 and sprocket B9 are respectively installed at the lower ends of two sets of rotating shafts 5, and sprocket A8 and sprocket B9 are connected by chain 10. When one set of rotating shafts 5 rotates, the rotating shaft 5 drives the chain 10 to rotate sprocket B9 through sprocket A8, which in turn causes the other set of rotating shafts 5 to rotate, so that the two sets of rotating shafts 5 rotate synchronously, which promotes the contact between the fermentation broth and microorganisms.

[0023] like Figure 4 and Figure 5The carbon source addition mechanism includes a storage tank 11, a delivery pump 12, a delivery hose 13, a discharge pipe 14, and a lifting mechanism. The storage tank 11 is mounted on the base plate 1, and the delivery pump 12 is mounted on the base plate 1. The input end of the delivery pump 12 is connected to the storage tank 11, and the output end of the delivery pump 12 is connected to the discharge pipe 14 through the delivery hose 13. The discharge pipe 14 is located in the chamber of the fermenter 3 and is mounted on the lifting mechanism, which is used to raise and lower the discharge pipe 14. The storage tank 11 stores glucose solution. When it is necessary to add carbon source to the fermenter 3 to promote the reaction, the delivery pump 12 is turned on, so that the carbon source in the storage tank 11 enters the chamber of the fermenter 3 in sequence through the delivery pump 12, the delivery hose 13, and the discharge pipe 14, which facilitates the addition of carbon source to the fermenter 3.

[0024] like Figure 5 The lifting mechanism includes a hydraulic cylinder 15, a push rod 16, and a fixing plate 17. The hydraulic cylinder 15 is fixedly installed at the upper end of the fermentation tank 3. The push rod 16 is slidably installed on the fermentation tank 3, and the upper end of the push rod 16 is connected to the output end of the hydraulic cylinder 15. The discharge pipe 14 is fixedly installed at the lower end of the push rod 16 through the fixing plate 17. When carbon source is added to the chamber of the fermentation tank 3 through the discharge pipe 14, the hydraulic cylinder 15 is opened. The hydraulic cylinder 15, through the push rod 16, causes the fixing plate 17 to drive the discharge pipe 14 to adjust its height, so that the discharge pipe 14 moves up and down during the discharge of carbon source, allowing the carbon source to be evenly discharged at different heights in the fermentation liquid, thus improving convenience. A thermometer is installed on the fermentation tank 3.

[0025] Example 2

[0026] Based on Example 1, the upper part of the fermenter 3 is provided with multiple sets of vent pipes, and each set of vent pipes is provided with a breathable sterilization membrane; the above arrangement facilitates the ventilation of the fermenter 3.

[0027] The stirring plate 6, motor 7, delivery pump 12, and hydraulic cylinder 15 of the fermentation kettle for hydroxyproline production of this utility model are all purchased from the market. Technical personnel in this industry only need to install and operate them according to the accompanying instruction manual, without requiring any creative work from those skilled in the art.

[0028] The above description is only a preferred embodiment of the present utility model. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the technical principles of the present utility model, and these improvements and modifications should also be considered within the protection scope of the present utility model.

Claims

1. A fermentation vessel for the production of hydroxyproline, comprising a bottom plate (1), a support (2), a fermentation tank (3), and a feeding pipe (4), wherein the fermentation tank (3) is fixedly installed on the upper end of the bottom plate (1) via the support (2), the fermentation tank (3) is provided with a chamber, the feeding pipe (4) is provided on the upper part of the fermentation tank (3), and a discharge pipe is provided on the lower part of the fermentation tank (3), and a valve is provided on the discharge pipe; characterized in that, It also includes a stirring mechanism and a carbon source adding mechanism. The stirring mechanism is installed on the fermentation tank (3) and has the function of stirring. The carbon source adding mechanism is connected to the fermentation tank (3) and is used to add carbon source to the fermentation tank (3).

2. The fermentation vessel for hydroxyproline production as described in claim 1, characterized in that, The stirring mechanism includes two sets of rotating shafts (5), multiple sets of stirring blades (6), a motor (7) and a transmission mechanism. The two sets of rotating shafts (5) are respectively rotatably installed on the left and right sides of the fermentation tank (3). The upper and lower ends of the two sets of rotating shafts (5) are located on the outside of the fermentation tank (3). Multiple sets of stirring blades (6) are installed on the two sets of rotating shafts (5). The multiple sets of stirring blades (6) are located in the chamber of the fermentation tank (3). The two sets of rotating shafts (5) are connected by the transmission mechanism. The motor (7) is installed on the upper end of the fermentation tank (3). The output end of the motor (7) is connected to one of the sets of rotating shafts (5).

3. A fermentation vessel for hydroxyproline production as described in claim 2, characterized in that, The transmission mechanism includes sprocket A (8), sprocket B (9) and chain (10). Sprocket A (8) and sprocket B (9) are respectively installed at the lower ends of two sets of rotating shafts (5). Sprocket A (8) and sprocket B (9) are connected by chain (10).

4. A fermentation vessel for hydroxyproline production as described in claim 1, characterized in that, The carbon source addition mechanism includes a storage tank (11), a delivery pump (12), a delivery hose (13), a discharge pipe (14), and a lifting mechanism. The storage tank (11) is installed on the base plate (1), the delivery pump (12) is installed on the base plate (1), the input end of the delivery pump (12) is connected to the storage tank (11), and the output end of the delivery pump (12) is connected to the discharge pipe (14) through the delivery hose (13). The discharge pipe (14) is located in the chamber of the fermenter (3), and the discharge pipe (14) is installed on the lifting mechanism. The lifting mechanism is used to lift the discharge pipe (14).

5. A fermentation vessel for hydroxyproline production as described in claim 4, characterized in that, The lifting mechanism includes a hydraulic cylinder (15), a push rod (16) and a fixing plate (17). The hydraulic cylinder (15) is fixedly installed on the upper end of the fermentation tank (3). The push rod (16) is slidably installed on the fermentation tank (3). The upper end of the push rod (16) is connected to the output end of the hydraulic cylinder (15). The discharge pipe (14) is fixedly installed on the lower end of the push rod (16) through the fixing plate (17).

6. A fermentation vessel for hydroxyproline production as described in claim 1, characterized in that, The upper part of the fermenter (3) is provided with multiple sets of vent pipes, and each set of vent pipes is provided with a breathable sterilization membrane.

7. A fermentation vessel for hydroxyproline production as described in claim 1, characterized in that, A thermometer is installed on the fermentation tank (3).

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