Reaction kettle for extracting medical intermediates

Abstract

The utility model discloses a reaction kettle for extracting medical intermediates, and relates to the technical field of reaction kettles. The reaction kettle comprises a base, a reaction kettle body and a cleaning box are fixedly connected to the left side and the right side of the top face of the base respectively, a position adjusting assembly is arranged in the middle of the top face of the base, mounting plates are arranged on the left side and the right side of the position adjusting assembly respectively, and the two mounting plates are movably connected with the top of the reaction kettle body and the top of the cleaning box in a clamped mode respectively. An air blowing assembly used for conveying air is installed on the surface of the installation plate, a self-cleaning assembly used for cleaning the air blowing assembly is installed on the surface of the cleaning box, and an electromagnetic valve is fixedly installed on the bottom face of the reaction kettle body. The operation process is more stable, automatic cleaning can be carried out, and cross contamination caused by liquid medicine residues is avoided.

Description

Technical Field

[0001] This utility model relates to the field of reaction vessel technology, specifically to a reaction vessel for extracting pharmaceutical intermediates. Background Technology

[0002] Pharmaceutical intermediates refer to chemical raw materials or products used in the synthesis of pharmaceuticals. They are key starting materials for the production of chemical active pharmaceutical ingredients (APIs), and the synthesis of chemical drugs depends on high-quality pharmaceutical intermediates.

[0003] Chinese patent document CN210495313U discloses a reaction vessel for extracting pharmaceutical intermediates, including a reaction vessel body, supporting legs, and a discharge port. The four supporting legs are evenly welded to the outer wall of the bottom of the reaction vessel body, and the discharge port is located in the middle of the bottom of the reaction vessel body. However, the above technical solution still has the following drawbacks: Existing technologies use air pipes and air stones to introduce gas into the reaction vessel, thereby increasing the fluidity of the solution and optimizing the dissolution efficiency of the medicinal materials. However, during use, the medicinal solution may remain in the air stones and air pipes, which may gradually clog them, reducing aeration efficiency and affecting the dissolution rate. Residual medicinal solution may also breed microorganisms, contaminating subsequent batches and affecting product quality. Furthermore, residues between different medicinal solutions may lead to cross-contamination, affecting efficacy and safety.

[0004] Therefore, a reaction vessel for the extraction of pharmaceutical intermediates is proposed. Utility Model Content

[0005] The purpose of this invention is to provide a reaction vessel for extracting pharmaceutical intermediates in order to solve the problems mentioned in the background art.

[0006] To achieve the above objectives, this utility model specifically adopts the following technical solution:

[0007] A reaction vessel for extracting pharmaceutical intermediates includes a base. A reaction vessel body and a cleaning chamber are fixedly connected to the left and right sides of the top surface of the base, respectively. A position adjustment component is provided in the center of the top surface of the base. Mounting plates are provided on both the left and right sides of the position adjustment component, and the two mounting plates are respectively movably engaged with the top of the reaction vessel body and the cleaning chamber. A gas blowing component for conveying gas is installed on the surface of the mounting plate. A self-cleaning component for cleaning the gas blowing component is installed on the surface of the cleaning chamber. A solenoid valve is fixedly installed on the bottom surface of the reaction vessel body.

[0008] Furthermore, the position adjustment assembly includes a mounting shell, which is fixedly installed in the middle of the top surface of the base. A motor is fixedly installed on the inner wall of the mounting shell, and a rotating shaft is fixedly connected to the output end of the motor. A support base is fixedly connected to the top end of the rotating shaft, and the support base is rotatably connected to the mounting shell. An electric push rod is fixedly installed on the top surface of the support base, and a connecting frame is fixedly connected to the telescopic end of the electric push rod. The connecting frame is fixedly connected to the two mounting plates.

[0009] Furthermore, the air-blowing assembly includes an air vent pipe, which is fixedly connected to the mounting plate. An annular pipe is fixedly connected to the end of the air vent pipe, and an air nozzle is fixedly connected to the bottom surface of the annular pipe.

[0010] Furthermore, the self-cleaning component includes an inlet pipe, which is fixedly connected to the cleaning box. A guide pipe is fixedly connected to the end of the inlet pipe, and a nozzle is fixedly connected to the top surface of the guide pipe. A drain pipe is fixedly inserted into the bottom surface of the cleaning box.

[0011] Furthermore, the number of nozzles and air nozzles is the same, and the nozzles and air nozzles are arranged in a one-to-one correspondence.

[0012] Furthermore, the surface of the mounting plate is provided with ventilation holes.

[0013] The beneficial effects of this utility model are as follows:

[0014] Pharmaceutical intermediates and extractants are placed inside the reactor body for dissolution and extraction. Gas is blown into the liquid through an aeration component to increase the fluidity of the solution, thereby accelerating the dissolution and extraction of the medicinal materials. The liquid can be removed by opening a solenoid valve. Subsequently, the positions of the aeration components located in the reactor body and the cleaning tank can be interchanged by operating a position adjustment component. The aeration components with liquid adhering to them are sent into the cleaning tank. The self-cleaning component can automatically clean the aeration components. The cleaned aeration components then enter the reactor body for continued operation. In use, this invention achieves the effect of facilitating the accelerated dissolution and extraction of medicinal materials through aeration, with more stable operation and automatic cleaning, avoiding cross-contamination caused by liquid residue. Attached Figure Description

[0015] Figure 1 This is a three-dimensional structural diagram of the present invention;

[0016] Figure 2 This is a cross-sectional view of the structure of this utility model;

[0017] Figure 3 This is a front sectional view of the position adjustment component structure of this utility model;

[0018] Reference numerals in the attached drawings: 1. Base; 2. Reactor body; 3. Position adjustment assembly; 301. Mounting shell; 302. Motor; 303. Rotating shaft; 304. Support base; 305. Electric push rod; 306. Connecting frame; 4. Mounting plate; 5. Gas blowing assembly; 501. Vent pipe; 502. Annular pipe; 503. Air nozzle; 6. Self-cleaning assembly; 601. Liquid inlet pipe; 602. Guide pipe; 603. Nozzle; 604. Drain pipe; 7. Cleaning box; 8. Vent hole; 9. Solenoid valve. Detailed Implementation

[0019] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this utility model, and not all embodiments. The components of the embodiments of this utility model described and shown in the accompanying drawings can generally be arranged and designed in various different configurations.

[0020] Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.

[0021] It should be noted that similar reference numerals and letters in the following figures indicate similar items; therefore, once an item is defined in one figure, it does not need to be further defined and explained in subsequent figures. Furthermore, the terms "first," "second," etc., are used only to distinguish descriptions and should not be construed as indicating or implying relative importance.

[0022] All electrical components mentioned in this article are connected to an external main controller and 220V AC mains power, and the main controller can be a conventional known device such as a computer that can control it.

[0023] In the description of the embodiments of this utility model, it should be noted that the terms "inner", "outer", "upper", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, or the orientation or positional relationship in which the utility model product is usually placed when in use. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0024] like Figures 1 to 3As shown, a reaction vessel for extracting pharmaceutical intermediates includes a base 1. A reaction vessel body 2 and a cleaning box 7 are fixedly connected to the left and right sides of the top surface of the base 1, respectively. A position adjustment component 3 is provided in the middle of the top surface of the base 1. Mounting plates 4 are provided on both the left and right sides of the position adjustment component 3, and the two mounting plates 4 are respectively movably engaged with the top of the reaction vessel body 2 and the cleaning box 7. A gas blowing component 5 for conveying gas is installed on the surface of the mounting plate 4. A self-cleaning component 6 for cleaning the gas blowing component 5 is installed on the surface of the cleaning box 7. A solenoid valve 9 is fixedly installed on the bottom surface of the reaction vessel body 2. More specifically, pharmaceutical intermediates and extractants are placed inside the reactor body 2 for dissolution and extraction. Gas is blown into the liquid through the aeration component 5 to increase the fluidity of the solution, thereby accelerating the dissolution and extraction of the medicinal materials. The liquid can be removed by opening the solenoid valve 9. Then, the positions of the aeration components 5 located in the reactor body 2 and the cleaning tank 7 can be interchanged by operating the position adjustment component 3. The aeration components 5 with the liquid adhering to them are sent into the cleaning tank 7. The self-cleaning component 6 can automatically clean the aeration components 5, and the cleaned aeration components 5 enter the reactor body 2 to continue operation.

[0025] The position adjustment assembly 3 includes a mounting shell 301, which is fixedly installed in the middle of the top surface of the base 1. A motor 302 is fixedly installed on the inner wall of the mounting shell 301. A rotating shaft 303 is fixedly connected to the output end of the motor 302. A support base 304 is fixedly connected to the top end of the rotating shaft 303. The support base 304 is rotatably connected to the mounting shell 301. An electric push rod 305 is fixedly installed on the top surface of the support base 304. A connecting frame 306 is fixedly connected to the telescopic end of the electric push rod 305. The connecting frame 306 is fixedly connected to two mounting plates 4. It should be noted that by operating the electric push rod 305, the connecting frame 306 is driven to move upward, which pulls the mounting plate 4 and the aeration assembly 5 to move, so that the aeration assembly 5 leaves the interior of the reactor body 2 and the cleaning box 7. Then, the motor 302 drives the rotating shaft 303 to rotate, thereby causing the support base 304 to rotate, so that the electric push rod 305 and the connecting frame 306 rotate 180 degrees. The aeration assembly 5 with the adhering medicine liquid will reach the top of the cleaning box 7, and the cleaned aeration assembly 5 will reach the top of the reactor body 2. Then, the electric push rod 305 controls the connecting frame 306 and the aeration assembly 5 to descend, so that the aeration assembly 5 can be lowered, and the cleaned aeration assembly 5 can be used to aerate, and the aeration assembly 5 with the adhering medicine liquid can enter the interior of the cleaning box 7 for cleaning.

[0026] The aeration assembly 5 includes a vent pipe 501, which is fixedly connected to the mounting plate 4. An annular pipe 502 is fixedly connected to the end of the vent pipe 501, and an air nozzle 503 is fixedly connected to the bottom surface of the annular pipe 502. More specifically, by connecting the vent pipe 501 to an external air source, gas can be introduced into the annular pipe 502, and gas can be introduced into the liquid medicine through the air nozzle 503, causing continuous convection inside the liquid medicine and accelerating drug dissolution.

[0027] The self-cleaning component 6 includes an inlet pipe 601, which is fixedly connected to the cleaning tank 7. A guide pipe 602 is fixedly connected to the end of the inlet pipe 601, and a nozzle 603 is fixedly connected to the top surface of the guide pipe 602. A drain pipe 604 is fixedly inserted into the bottom surface of the cleaning tank 7. It should be noted that the inlet pipe 601 is connected to an external cleaning water source, allowing cleaning water to enter the guide pipe 602 and be sprayed out through the nozzle 603. This cleans the vent pipe 501, the annular pipe 502, and the air nozzle 503, preventing chemical residue. Wastewater can be discharged through the drain pipe 604.

[0028] The number of nozzles 603 and air nozzles 503 is the same, and the nozzles 603 and air nozzles 503 are set in a one-to-one correspondence. More specifically, by setting the nozzles 603 and air nozzles 503 in a one-to-one correspondence, the cleaning of air nozzles 503 is more direct, thus enhancing the cleaning effect.

[0029] A vent hole 8 is provided through the surface of the mounting plate 4. It should be noted that by providing the vent hole 8, the gas inside the reactor body 2 can be smoothly discharged.

[0030] In summary: pharmaceutical intermediates and extractants are placed inside the reactor body 2 for dissolution and extraction. Gas is blown into the liquid through the aeration component 5 to increase the fluidity of the solution, thereby accelerating the dissolution and extraction of the medicinal materials. The liquid can be removed by opening the solenoid valve 9. Subsequently, the positions of the aeration components 5 located in the reactor body 2 and the cleaning tank 7 can be interchanged by operating the position adjustment component 3. The aeration components 5 with medicinal materials adhering to them are sent into the cleaning tank 7. The self-cleaning component 6 can automatically clean the aeration components 5. The cleaned aeration components 5 then enter the reactor body 2 for continued operation. In use, this invention achieves the effect of facilitating the accelerated dissolution and extraction of medicinal materials by aeration, with more stable operation and automatic cleaning, avoiding cross-contamination caused by residual medicinal materials.

[0031] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. A reaction vessel for extracting pharmaceutical intermediates, characterized in that, The system includes a base (1), on which a reactor body (2) and a cleaning box (7) are fixedly connected to the left and right sides of the top surface of the base (1), respectively. A position adjustment component (3) is provided in the middle of the top surface of the base (1), and mounting plates (4) are provided on both the left and right sides of the position adjustment component (3). The two mounting plates (4) are movably engaged with the top of the reactor body (2) and the cleaning box (7), respectively. A gas blowing component (5) for conveying gas is installed on the surface of the mounting plate (4), and a self-cleaning component (6) for cleaning the gas blowing component (5) is installed on the surface of the cleaning box (7). A solenoid valve (9) is fixedly installed on the bottom surface of the reactor body (2).

2. The reaction vessel for extracting pharmaceutical intermediates according to claim 1, characterized in that, The position adjustment component (3) includes a mounting shell (301), which is fixedly mounted on the top center of the base (1). A motor (302) is fixedly mounted on the inner wall of the mounting shell (301). A rotating shaft (303) is fixedly connected to the output end of the motor (302). A support base (304) is fixedly connected to the top end of the rotating shaft (303). The support base (304) is rotatably connected to the mounting shell (301). An electric push rod (305) is fixedly mounted on the top surface of the support base (304). A connecting frame (306) is fixedly connected to the telescopic end of the electric push rod (305). The connecting frame (306) is fixedly connected to the two mounting plates (4).

3. The reaction vessel for extracting pharmaceutical intermediates according to claim 2, characterized in that, The air-blowing assembly (5) includes an air pipe (501), and the air pipe (501) is fixedly connected to the mounting plate (4). An annular pipe (502) is fixedly connected to the end of the air pipe (501), and an air nozzle (503) is fixedly connected to the bottom surface of the annular pipe (502).

4. The reaction vessel for extracting pharmaceutical intermediates according to claim 3, characterized in that, The self-cleaning component (6) includes an inlet pipe (601) and is fixedly connected to the cleaning box (7). A guide pipe (602) is fixedly connected to the end of the inlet pipe (601), and a nozzle (603) is fixedly connected to the top surface of the guide pipe (602). A drain pipe (604) is fixedly inserted into the bottom surface of the cleaning box (7).

5. The reaction vessel for extracting pharmaceutical intermediates according to claim 4, characterized in that, The number of nozzles (603) and air nozzles (503) is the same, and the nozzles (603) and air nozzles (503) are arranged in a one-to-one correspondence.

6. The reaction vessel for extracting pharmaceutical intermediates according to claim 2, characterized in that, The surface of the mounting plate (4) is provided with ventilation holes (8).

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