Extraction mechanism for preparation of regadenoson injection
The stirring and circulation mechanism promotes sufficient contact and molecular diffusion between the solvent and solute, solving the problem of insufficient contact in traditional extraction methods and improving the extraction efficiency and uniformity of Reganoxon injection.
Patent Information
- Application Number
- CN202520366920.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-04
- Publication Date
- 2026-01-27
- Estimated Expiration
- 2035-03-04
AI Technical Summary
In traditional extraction methods, insufficient contact between the solvent and the solution to be extracted leads to uneven molecular diffusion, resulting in low extraction efficiency and potential waste of raw materials or incomplete extraction.
An extraction device including a stirring mechanism and a circulation mechanism is used. The mixing of the solution is promoted by the counter-rotation of the stirring rod and the reciprocating motion of the lifting rod. Combined with the circulation action of the pump, the solvent and solute are fully contacted and molecules diffuse.
It improves the extraction rate and efficiency, ensures that the extraction solution is evenly distributed in the solution to be separated, avoids local concentration unevenness, reduces batch-to-batch differences, and achieves more consistent extraction results.
Smart Images

Figure CN223831841U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of extraction mechanism technology, and in particular to an extraction mechanism for preparing Reganoxane injection. Background Technology
[0002] Reganoxone injection is a selective A2A adenosine receptor agonist primarily used to aid in the diagnosis of myocardial ischemia and is suitable for patients who cannot undergo exercise stress testing. It promotes coronary artery dilation and increases local blood flow by activating relevant receptors in the smooth muscle of the coronary arteries, thus aiding physicians in accurate diagnosis.
[0003] In the preparation of Reganoxon injection, the active ingredients in the raw materials need to be extracted. Traditional extraction methods often suffer from problems such as insufficient contact between the solvent and the solution to be extracted, and uneven molecular diffusion, resulting in low extraction efficiency and potential waste of raw materials or incomplete extraction. Therefore, improving the extraction rate and ensuring sufficient contact between the solvent and solute are key to improving the quality and production efficiency of Reganoxon injection.
[0004] Therefore, we provide an extraction apparatus for preparing Reganoxane injection. Utility Model Content
[0005] The purpose of this invention is to address the aforementioned technical problems by providing an extraction mechanism for preparing Reganoxane injection, which allows the extraction solution and the solution to be extracted to fully contact and mix, thereby improving extraction efficiency.
[0006] In view of this, the present invention provides an extraction mechanism for preparing Reganoxon injection, including a mixing chamber, wherein the mixing chamber is provided with a stirring mechanism and a circulation mechanism, the stirring mechanism includes a stirring assembly, the stirring assembly includes a support, the support is fixedly installed on the side of the mixing chamber, a vertical plate is fixedly installed on the top of the support, a first motor is fixedly installed on the side of the vertical plate, the shaft end of the first motor passes through the vertical plate and a turntable is fixedly installed thereon, a sliding rod is fixedly installed on the turntable, a limiting plate is fixedly installed on the side of the vertical plate, a lifting rod slides through the limiting plate, a track is fixedly installed on the top of the lifting rod, the sliding rod slides in the track, and an installation plate is fixedly installed on the bottom of the lifting rod;
[0007] The circulation mechanism includes a circulation component, which includes a receiving plate. The receiving plate is fixedly installed on the surface of the mixing tank. A pump body is fixedly installed on the top of the receiving plate. A first conduit and a second conduit are fixedly installed on the surface of the mixing tank. Valves are fixedly installed on both the first conduit and the second conduit.
[0008] Preferably, one end of the first conduit is fixedly connected to the water inlet pipe of the pump body, and one end of the second conduit is fixedly connected to the water outlet pipe of the pump body.
[0009] Preferably, both the first and second conduits are L-shaped, and a third conduit is fixedly installed on the second conduit, with a valve fixedly installed on the third conduit.
[0010] Preferably, the bottom end of the mounting plate is rotatably connected to a first pipe, the top end of the first pipe is closed, the bottom end of the first pipe is open, the inner wall of the first pipe is rotatably connected to a second pipe, and the inner wall of the second pipe is fixedly connected to a connecting rod, the connecting rod is cylindrical, the bottom end of the connecting rod is fixedly installed with a first stirring rod, the first stirring rod is square, and the surface of the second pipe is fixedly installed with a second stirring rod, the second stirring rod is square.
[0011] Preferably, a first toothed ring is fixedly installed on the first pipe, a second toothed ring is fixedly installed on the second pipe, a mounting base is fixedly installed at the bottom end of the mounting plate, a second motor is fixedly installed on the surface of the mounting base, and a gear is fixedly installed at the shaft end of the second motor, the gear meshing with the first toothed ring and the second toothed ring.
[0012] Preferably, a transparent glass is fixedly installed on the surface of the mixing chamber. The transparent glass is in the shape of a square block and penetrates the inner wall of the mixing chamber.
[0013] Compared with the prior art, this utility model provides an extraction mechanism for preparing Reganoxan injection, which has the following beneficial effects:
[0014] This invention, by incorporating a stirring mechanism, can accelerate molecular diffusion between the solution to be separated and the extraction solution, enabling them to reach a more uniform mixing state in a short time, thereby improving the rate and efficiency of the extraction process. At the same time, stirring helps ensure that the extraction solution is evenly distributed throughout the solution to be separated, avoiding situations where the local concentration is too high or too low.
[0015] This invention, by incorporating a circulation mechanism, facilitates faster flow of liquid within the mixing chamber, thereby accelerating molecular diffusion between the solution to be separated and the extraction solution, thus improving the rate and efficiency of the extraction process.
[0016] The parts of this device not covered herein are the same as or can be implemented using existing technologies. This utility model has a simple structure and is easy to operate. Attached Figure Description
[0017] Figure 1 This is a schematic diagram of the overall structure of an extraction mechanism for preparing Reganoxon injection proposed in this utility model;
[0018] Figure 2 This is a schematic diagram of the stirring mechanism of an extraction mechanism for preparing Reganoxane injection proposed in this utility model;
[0019] Figure 3 This is a schematic diagram of the gears in an extraction mechanism for preparing Reganoxane injection according to this utility model;
[0020] Figure 4 This is a schematic diagram of the turntable for an extraction mechanism used in the preparation of Reganoxon injection proposed in this utility model.
[0021] In the diagram: 1. Mixing tank; 2. Circulation assembly; 21. First conduit; 22. Receiving plate; 23. Pump body; 24. Third conduit; 25. Second conduit; 3. Stirring assembly; 31. Second stirring rod; 32. First stirring rod; 33. Lifting rod; 34. Slide rod; 35. Bracket; 36. First motor; 37. Turntable; 38. Track; 39. Second pipe; 310. Vertical plate; 311. Limiting plate; 312. Mounting plate; 313. Connecting rod; 314. Second gear ring; 315. First pipe; 316. First gear ring; 317. Mounting base; 318. Second motor; 319. Gear; 4. Transparent glass. Detailed Implementation
[0022] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.
[0023] In the description of this utility model, it should be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.
[0024] Example 1: An extraction mechanism for preparing Reganoxan injection, such as... Figures 1-4As shown, the system includes a mixing tank 1, which is equipped with a stirring mechanism and a circulation mechanism. The stirring mechanism includes a stirring assembly 3, which includes a support 35. The support 35 is fixedly installed on the side of the mixing tank 1. A vertical plate 310 is fixedly installed on the top of the support 35. A first motor 36 is fixedly installed on the side of the vertical plate 310. The shaft end of the first motor 36 passes through the vertical plate 310 and is fixedly installed on a turntable 37. A slide rod 34 is fixedly installed on the turntable 37. A limit plate 311 is fixedly installed on the side of the vertical plate 310. A lifting rod 33 slides through the limit plate 311. A track 38 is fixedly installed on the top of the lifting rod 33. The slide rod 34 slides in the track 38. An installation plate 312 is fixedly installed on the bottom of the lifting rod 33.
[0025] The circulation mechanism includes a circulation component 2, which includes a receiving plate 22. The receiving plate 22 is fixedly installed on the surface of the mixing tank 1. A pump body 23 is fixedly installed on the top of the receiving plate 22. A first conduit 21 and a second conduit 25 are fixedly installed on the surface of the mixing tank 1. Valves are fixedly installed on both the first conduit 21 and the second conduit 25.
[0026] The bottom end of the mounting plate 312 is rotatably connected to a first pipe 315. The top end of the first pipe 315 is closed, and the bottom end of the first pipe 315 is open. The inner wall of the first pipe 315 is rotatably connected to a second pipe 39.
[0027] A connecting rod 313 is fixedly connected to the inner wall of the first pipe 315. The connecting rod 313 is cylindrical. A first stirring rod 32 is fixedly installed at the bottom end of the connecting rod 313. The first stirring rod 32 is square. A second stirring rod 31 is fixedly installed on the surface of the second pipe 39. The second stirring rod 31 is square.
[0028] A first gear ring 316 is fixedly installed on the first pipe 315, a second gear ring 314 is fixedly installed on the second pipe 39, a mounting base 317 is fixedly installed at the bottom end of the mounting plate 312, a second motor 318 is fixedly installed on the surface of the mounting base 317, and a gear 319 is fixedly installed at the shaft end of the second motor 318. The gear 319 meshes with the first gear ring 316 and the second gear ring 314.
[0029] A transparent glass 4 is fixedly installed on the surface of the mixing box 1. The transparent glass 4 is square in shape and penetrates the inner wall of the mixing box 1.
[0030] In use, the raw material solution containing Reganoxant and the extraction solvent are added into the mixing tank 1. Then, the first motor 36 and the second motor 318 are started. The second motor 318 drives the gear 319 to rotate. The gear 319 meshes with the first gear ring 316 and the second gear ring 314, which simultaneously drives the first pipe 315 and the second pipe 39 to rotate in opposite directions. When the first pipe 315 and the second pipe 39 rotate, they drive the first stirring rod 32 and the second stirring rod 31 to rotate in opposite directions. At the same time, the first motor 36 drives the turntable 37 to rotate. The turntable 37 drives the slide rod 34 to perform circular motion. During the movement, the slide rod 34 drives the lifting rod 33 along the track 38. The through hole of 311 moves vertically back and forth. When the lifting rod 33 moves vertically back and forth, it will drive the first stirring rod 32 and the second stirring rod 31 to move vertically back and forth through the mounting plate 312, the first pipe 315 and the second pipe 39. Through the above settings, the molecular diffusion between the solution to be separated and the extraction solution can be accelerated, so that the two can reach a more uniform mixing state in a short time, thereby improving the rate and efficiency of the extraction process. At the same time, stirring helps to ensure that the extraction solution is evenly distributed in the entire solution to be separated, avoiding local concentrations that are too high or too low. This helps to achieve a more consistent extraction effect and reduce batch-to-batch differences. After stirring is completed, stirring is stopped and the mixture is allowed to stand for a period of time to allow the two phases to naturally separate, thereby achieving the purpose of extraction. Furthermore, the transparent glass 4 facilitates the observation of the extraction of the solution.
[0031] Example 2: An extraction mechanism for preparing Reganoxan injection, such as... Figures 1-4 As shown, one end of the first conduit 21 is fixedly connected to the inlet pipe of the pump body 23, and one end of the second conduit 25 is fixedly connected to the outlet pipe of the pump body 23.
[0032] The first conduit 21 and the second conduit 25 are both L-shaped. A third conduit 24 is fixedly installed on the second conduit 25, and a valve is fixedly installed on the third conduit 24.
[0033] During the stirring process, the pump body 23 is started. The pump body 23 draws the solution in the mixing tank 1 through the first conduit 21 and discharges it back into the mixing tank 1 through the second conduit 25. The above settings help to accelerate the molecular diffusion between the solution to be separated and the extraction solution, so that the two can reach a more uniform mixing state in a short time. Furthermore, with the third conduit 24, when it is necessary to remove the solution, the valve at the second conduit 25 is closed and the valve at the third conduit 24 is opened, and then the pump body 23 is started again to draw the solution out of the mixing tank 1.
[0034] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and the inventive concept of the present utility model, should be included within the protection scope of the present utility model.
Claims
1. An extraction mechanism for preparing Reganoxan injection, comprising a mixing chamber (1), wherein the mixing chamber (1) is provided with a stirring mechanism and a circulation mechanism, characterized in that: The stirring mechanism includes a stirring assembly (3), which includes a bracket (35). The bracket (35) is fixedly installed on the side of the mixing box (1). A vertical plate (310) is fixedly installed at the top of the bracket (35). A first motor (36) is fixedly installed on the side of the vertical plate (310). The shaft end of the first motor (36) passes through the vertical plate (310) and is fixedly installed on a turntable (37). A slide rod (34) is fixedly installed on the turntable (37). A limit plate (311) is fixedly installed on the side of the vertical plate (310). A lifting rod (33) slides through the limit plate (311). A track (38) is fixedly installed at the top of the lifting rod (33). The slide rod (34) slides in the track (38). An installation plate (312) is fixedly installed at the bottom of the lifting rod (33). The circulation mechanism includes a circulation component (2), which includes a receiving plate (22). The receiving plate (22) is fixedly installed on the surface of the mixing tank (1). A pump body (23) is fixedly installed on the top of the receiving plate (22). A first conduit (21) and a second conduit (25) are fixedly installed on the surface of the mixing tank (1). Valves are fixedly installed on both the first conduit (21) and the second conduit (25).
2. The extraction mechanism for preparing Reganoxan injection according to claim 1, characterized in that, One end of the first conduit (21) is fixedly connected to the inlet pipe of the pump body (23), and one end of the second conduit (25) is fixedly connected to the outlet pipe of the pump body (23).
3. The extraction mechanism for preparing Reganoxan injection according to claim 1, characterized in that, The first conduit (21) and the second conduit (25) are both L-shaped. A third conduit (24) is fixedly installed on the second conduit (25), and a valve is fixedly installed on the third conduit (24).
4. The extraction mechanism for preparing Reganoxan injection according to claim 1, characterized in that, The bottom end of the mounting plate (312) is rotatably connected to a first pipe (315), the top end of the first pipe (315) is closed, the bottom end of the first pipe (315) is open, and the inner wall of the first pipe (315) is rotatably connected to a second pipe (39).
5. The extraction mechanism for preparing Reganoxan injection according to claim 4, characterized in that, A connecting rod (313) is fixedly connected to the inner wall of the first pipe (315). The connecting rod (313) is cylindrical. A first stirring rod (32) is fixedly installed at the bottom end of the connecting rod (313). The first stirring rod (32) is square. A second stirring rod (31) is fixedly installed on the surface of the second pipe (39). The second stirring rod (31) is square.
6. The extraction mechanism for preparing Reganoxan injection according to claim 4, characterized in that, A first toothed ring (316) is fixedly installed on the first pipe (315), a second toothed ring (314) is fixedly installed on the second pipe (39), a mounting base (317) is fixedly installed at the bottom end of the mounting plate (312), a second motor (318) is fixedly installed on the surface of the mounting base (317), a gear (319) is fixedly installed at the shaft end of the second motor (318), and the gear (319) meshes with the first toothed ring (316) and the second toothed ring (314).
7. The extraction mechanism for preparing Reganoxan injection according to claim 1, characterized in that, A transparent glass (4) is fixedly installed on the surface of the mixing box (1). The transparent glass (4) is square in shape and penetrates the inner wall of the mixing box (1).