Portable low-temperature oxygen-carrying organ transfer box

The portable cryogenic oxygen-carrying organ transport box, which integrates a miniature oxygen generator and a temperature control system, solves the hypoxia problem of traditional organ transport boxes, improves the activity and quality of organs during transportation, reduces the risk of ischemia-reperfusion injury, and ensures successful transplantation.

CN223860057UActive Publication Date: 2026-02-03GENERAL HOSPITAL OF SOUTHERN THEATRE COMMAND OF PLA +1
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202422122055.1
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-30
Publication Date
2026-02-03
Estimated Expiration
2034-08-30

AI Technical Summary

Technical Problem

Traditional organ transport boxes lack effective oxygen perfusion capabilities, causing organs to be in a low-temperature and hypoxic environment for extended periods. This leads to the accumulation of toxic metabolites, increases the risk of ischemia-reperfusion injury, and reduces transplant survival rates and functional recovery outcomes.

Method used

A portable cryogenic oxygen-carrying organ transport box was designed, integrating a micro oxygen generator, centrifugal pump, oxygenator and temperature control system to provide a stable and adjustable oxygen supply. Combined with a flexible container bag and semiconductor components, it ensures that organs receive sufficient oxygen and maintain a suitable temperature in a cryogenic environment.

Benefits of technology

It effectively avoids the accumulation of toxic metabolites in organs under low temperature and hypoxia, reduces ischemia-reperfusion injury, improves organ viability and quality, and provides a guarantee for successful transplantation. At the same time, the device is miniaturized and easy to carry and operate.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN223860057U_ABST
    Figure CN223860057U_ABST
Patent Text Reader

Abstract

The utility model provides a portable low-temperature oxygen-carrying organ transfer box which comprises a machine shell and a cover plate, a miniature oxygen generator is installed on the machine shell, two sets of air outlet connectors are arranged on the machine shell, and the miniature oxygen generator is connected with the two sets of air outlet connectors through connecting pipes. The cover plate is rotatably connected with the shell to form a placement cavity, a storage assembly is arranged in the placement cavity, the storage assembly comprises a covering shell, a container bag and an oxygenator are arranged in the covering shell, two groups of oxygen circulation openings are formed in the container bag, one group of air outlet connectors are connected with the oxygenator, and the other group of air outlet connectors are connected with one group of oxygen circulation openings; a control panel is arranged on the machine shell, and a power supply and a main control board are installed on one side of the machine shell. According to the transfer box, the miniature oxygen generator is installed on the machine shell, the miniature oxygen generator is communicated with the oxygenator and the container bag in the storage assembly through the connecting pipe, oxygen can be supplied to organs at low temperature, accumulation of toxic metabolites of the organs is effectively avoided, and the risk of ischemia reperfusion injury is reduced.
Need to check novelty before this filing date? Find Prior Art

Description

TECHNICAL FIELD

[0001] The utility model belongs to organ transport box technical field, more specifically, especially, it is related to portable low temperature oxygen-carrying organ transport box. BACKGROUND

[0002] In the transportation of organs, because the activity and quality of organs are crucial to the success of transplantation surgery, organ transport boxes are often used to ensure that organs are not contaminated and to ensure the quality of organs, laying the foundation for successful organ transplantation. Organ transport boxes usually use low-temperature static cold preservation methods. By placing organs in a 4℃ environment, the metabolism and enzyme decomposition of donor organs are inhibited by low temperature, thereby reducing energy consumption and prolonging the time of organ ex vivo preservation. However, donor organs are still in a low-speed metabolic state at low temperature, but the traditional organ transport box does not have effective oxygen perfusion function, which causes the organs to be in a low-temperature hypoxic environment for a long time, easily causing the accumulation of toxic metabolites, leading to severe ischemia-reperfusion injury after organ reflow, and reducing the survival rate and functional recovery effect after organ transplantation. SUMMARY

[0003] To solve the above technical problems, the utility model provides a portable low-temperature oxygen-carrying organ transport box to solve the technical problem that the traditional organ transport box does not have effective oxygen perfusion function, causing the organs to be in a low-temperature hypoxic environment for a long time, causing the accumulation of toxic metabolites, and the organs are prone to ischemia-reperfusion injury after reflow, thereby reducing the survival rate and functional recovery effect after organ transplantation.

[0004] The purpose and effect of the portable low-temperature oxygen-carrying organ transport box of the utility model are achieved by the following specific technical means:

[0005] The portable low-temperature oxygen-carrying organ transport box comprises a machine shell and a cover plate, a miniature oxygen generator is installed on the machine shell, two groups of gas outlet joints are arranged on the machine shell, and the miniature oxygen generator is connected with the two groups of gas outlet joints through connecting pipes; the cover plate and the machine shell are rotatably connected to form a placing cavity, a storage assembly is arranged in the placing cavity, the storage assembly comprises a sleeve package shell, a container bag and an oxygenator are arranged in the sleeve package shell, two groups of oxygen flow ports are arranged on the container bag, one group of the gas outlet joints is connected with the oxygenator, and the other group of the gas outlet joints is connected with one group of the oxygen flow ports; a control panel is arranged on the machine shell, and a power supply and a main control board are installed on one side of the machine shell.

[0006] According to a preferred embodiment, the storage assembly further comprises a centrifugal pump, which is installed on one side of the package shell, one end of the centrifugal pump is communicated with the container bag through a pipeline, and the other end is connected with the oxygenator through the pipeline; a micro-thrombus filter is arranged in the package shell, and the oxygenator is connected with the micro-thrombus filter through the pipeline.

[0007] According to a preferred embodiment, the container bag is provided with a first perfusion liquid flow port and a second perfusion liquid flow port, the micro-thrombus filter is connected with the first perfusion liquid flow port or the second perfusion liquid flow port through a communication pipe, a pressure sensor is arranged on the communication pipe, a data acquisition connector is arranged on the machine shell, and the pressure sensor is connected with the data acquisition connector through a wire.

[0008] According to a preferred embodiment, the container bag is provided with a first perfusion liquid flow port and a second perfusion liquid flow port, the micro-thrombus filter is connected with the first perfusion liquid flow port or the second perfusion liquid flow port through a communication pipe, a pressure sensor is arranged on the communication pipe, a data acquisition connector is arranged on the machine shell, and the pressure sensor is connected with the data acquisition connector through a wire.

[0009] According to a preferred embodiment, the machine shell is provided below a bottom plate connected with the machine shell to form a mounting cavity, a semiconductor assembly is arranged in the mounting cavity, a plurality of through grooves are formed on one side of the machine shell, the mounting cavity is communicated with the external environment through the through grooves, and a plurality of fans are arranged in the mounting cavity and clamped in the through grooves.

[0010] According to a preferred embodiment, the machine shell is provided with a buckle base, the package shell is provided with a buckle top base corresponding to the buckle base, the buckle base is clamped in the buckle top base, and the package shell and the machine shell are detachably connected.

[0011] According to a preferred embodiment, the container bag is provided with a pull rope, the container bag is opened or closed through the pull rope, both sides of the machine shell are provided with a plurality of hooks, and two groups of hanging belts are arranged above the machine shell and connected with the hooks at both ends.

[0012] According to a preferred embodiment, the machine shell is provided with a drawer, the drawer is slidably connected with the machine shell, the hanging belt can be placed in the drawer, and a backup battery is further arranged in the machine shell.

[0013] Compared with the prior art, the utility model has the advantages that:

[0014] 1. The machine shell and the cover plate are connected to form a placing cavity, and a storage assembly is arranged in the placing cavity, the storage assembly is used for stable protection of organs. A miniature oxygen generator is arranged in the machine shell, the miniature oxygen generator is designed by integration, oxygen with stable and adjustable concentration is provided for perfusion, oxygen output is divided into two ways, and the two ways are connected with two groups of air outlet connectors on the machine shell. An oxygenator and two groups of oxygen flow openings are arranged on a sleeve package shell in the storage assembly, one group of air outlet connectors is connected with the oxygenator, and the other group is connected with one group of oxygen flow openings, surface oxygenation and solution physical oxygenation functions are realized, and oxygenation performance is greatly improved. Meanwhile, the oxygen partial pressure and oxygenation detection function of the integrated miniature oxygen generator can realize intermittent oxygen supply and reduce energy consumption. Toxic metabolic products caused by long-term hypothermia and anoxia of organs are avoided, the risk of ischemia-reperfusion injury is reduced, and the activity and quality of organs in the transportation process are significantly improved, thereby providing guarantee for the success of organ transplantation.

[0015] 2. In terms of temperature control, the sealing treatment of the interfaces of the consumable sleeve package, the setting of ice slurry between the sleeve package shell and the container bag in the storage assembly, and the fixation of the machine shell flip cover improve the heat preservation performance. Secondly, the semiconductor assembly below the machine shell can accurately control the temperature, one side cools to maintain the low-temperature effect, and the heat of the other side is discharged by the bottom fan, so that the organ is always in a suitable low-temperature environment. In addition, the integrated temperature monitoring device can accurately feedback temperature information in real time, and ensure accurate temperature control. The problem that the traditional equipment is difficult to maintain the temperature stability of the organ is solved, and ideal temperature conditions are created for long-term preservation and transportation of the organ.

[0016] 3. The transportation box realizes miniaturization and light weight of the equipment by integrating components such as a small centrifugal pump, a miniature oxygen generator, a backup battery and a small oxygenator. The soft material setting of the container bag and the silica gel soft film can better fit the organ, facilitate manual change of the perfusion direction and angle, and be suitable for perfusion of various organs. The storage assembly can directly take out the solution, and is seamlessly compatible with other low-temperature preservation boxes and operating tables. Meanwhile, a plurality of hooks are arranged on the two sides of the machine shell, a plurality of lifting belts are arranged above the machine shell, the lifting belts are connected with the hooks, and the transportation box is convenient to carry; when moving for a short distance, the machine shell can be directly buckled on the buckle positions on the two sides for movement, when moving for a long distance, the lifting belts can be used, and the lifting belts can be placed in the drawer arranged on one side of the machine shell when not in use. BRIEF DESCRIPTION OF DRAWINGS

[0017] Figure 1 is a structure schematic view of the utility model after assembly;

[0018] Figure 2 is a structure schematic view of the utility model after disassembly;

[0019] Figure 3 is a first view structure schematic view of the storage assembly;

[0020] Figure 4 is a second perspective view of the storage assembly;

[0021] Figure 5 is a bottom view of the cover;

[0022] Figure 6 is a structural schematic view of the casing.

[0023] In the drawings, the correspondence between the component names and the reference numerals is as follows:

[0024] 11, casing; 12, air outlet; 13, control panel; 14, power supply; 15, main control board; 16, data acquisition connector; 17, buckle base; 18, hook; 21, cover plate; 22, bottom plate; 23, sling; 24, drawer; 31, micro oxygen generator; 32, semiconductor assembly; 33, fan; 34, backup battery; 401, cover; 402, container bag; 403, oxygenator; 404, oxygen flow port; 405, centrifugal pump; 406, micro plug filter; 407, first perfusion fluid flow port; 408, second perfusion fluid flow port; 409, pressure sensor; 410, silica gel soft film; 411, support frame; 412, buckle top seat; 413, pull rope. DETAILED DESCRIPTION

[0025] The embodiments of the present application will be further described in detail below with reference to the drawings and examples. The following examples are used to illustrate the technical solutions of the present application, but cannot be used to limit the protection scope of the present application.

[0026] Example:

[0027] As Figure 1 , 2, 6, the utility model provides a portable low temperature oxygen carrying organ transfer case, including organic shell 11 and apron 21, the organic shell 11 has good durability and anti -wear performance. The micro -oxygen generator 31 is installed on the shell 11, and the micro -oxygen generator 31 adopts advanced oxygen making technology, and oxygen can be made efficiently and stably. Two groups of gas outlets 12 are arranged on the shell 11, and the micro -oxygen generator 31 is connected with the two groups of gas outlets 12 through connecting pipes respectively, to ensure the smooth delivery of oxygen, and the connection is sealed tightly, to prevent the possibility of oxygen leakage. The apron 21 and the shell 11 are rotatably connected to ensure that they are tightly closed, and when the apron 21 and the shell 11 are closed, a placing cavity is formed. A storage assembly is arranged in the placing cavity, and the storage assembly includes a sleeve package shell 401, which has excellent pressure resistance and impact resistance, and can effectively protect the internal devices. The sleeve package shell 401 is provided with a container bag 402 and an oxygenation device 403, the container bag 402 adopts special materials meeting the biological compatibility standard, which can reduce the friction and damage to the organ. The container bag 402 is provided with two groups of oxygen flow ports 404, one group of gas outlets 12 is connected with the oxygenation device 403, to ensure that oxygen can enter the oxygenation device 403 for oxygenation; the other group of gas outlets 12 is connected with one group of oxygen flow ports 404, to provide sufficient oxygen for the organ in the container bag 402. The shell 11 is provided with a control panel 13, and various function keys are arranged reasonably, to facilitate the user to operate and set parameters. A power supply 14 is installed on one side of the shell 11, and the power supply 14 is connected with the external 220v power supply, to provide stable and durable power support for the whole device. At the same time, the main control board 15 adopts integrated technology, has operation and control ability, can finely control the operation parameters of the device, and ensures that the device is always in the best working state.

[0028] As Figures 2 to 6 shown, the storage assembly further includes a centrifugal pump 405, the centrifugal pump 405 is installed on one side of the sleeve package shell 401, one end of the centrifugal pump 405 is communicated with the container bag 402 through a pipeline, and the other end is also connected with the oxygenation device 403 through a pipeline, to ensure the smooth flow of liquid in the system, and provide stable power support for the whole perfusion process. The microembolus filter 406 is further arranged in the sleeve package shell 401, the microembolus filter 406 can effectively capture and filter out possible microembolus and impurities, so as to guarantee the purity and safety of the perfusion liquid. The oxygenation device 403 is connected with the microembolus filter 406 through a pipeline, to form a complete liquid circulation path. The container bag 402 is provided with a first perfusion liquid flow port 407 and a second perfusion liquid flow port 408, and the two perfusion liquid flow ports provide more perfusion options and flexibility. The microembolus filter 406 is connected with the first perfusion liquid flow port 407 or the second perfusion liquid flow port 408 through a communication pipe, to adapt to different perfusion requirements and operation modes.

[0029] A pressure sensor 409 is installed on the connecting pipe, which can monitor the pressure changes of the liquid in the connecting pipe in real time. A data acquisition connector 16 is installed on the housing 11. The pressure sensor 409 is connected to the data acquisition connector 16 through a durable wire, ensuring that the pressure data can be accurately and quickly transmitted to the control system of the equipment, thereby realizing real-time monitoring and adjustment of the pressure during the filling process.

[0030] A silicone soft membrane 410 is provided inside the container bag 402. The silicone soft membrane 410 has multiple sets of through holes to ensure the flow of liquid and gas. Both the container bag 402 and the silicone soft membrane 410 are made of soft materials with good flexibility and extensibility, which can better fit the stored organs and provide wrapping and protection.

[0031] The outer casing 401 contains a support frame 411, on which the container bag 402 is secured, ensuring it does not shift or shake during transport and handling. A placement cavity is formed between the container bag 402 and the outer casing 401, where ice slush can be placed. The presence of ice slush effectively maintains a low-temperature environment, providing ideal temperature conditions for organ preservation.

[0032] like Figure 2 , 4 As shown, a base plate 22 is provided below the housing 11, and the base plate 22 is connected to the housing 11 to form a mounting cavity. A semiconductor component 32 is disposed within this mounting cavity. The semiconductor component 32 has efficient cooling and temperature control performance, capable of regulating the internal temperature. Multiple sets of through slots are formed on one side of the housing 11, allowing the mounting cavity to communicate with the external environment, ensuring air circulation and heat dissipation. Multiple sets of fans 33 are also installed within the mounting cavity, and the fans 33 are fitted into the through slots. The operation of the fans 33 accelerates heat dissipation, improves heat dissipation efficiency, and ensures stable performance of the equipment during long-term operation.

[0033] The housing 11 has a snap-fit ​​base 17 inside, and the outer casing 401 has a corresponding snap-fit ​​top seat 412. The snap-fit ​​base 17 is snapped into the snap-fit ​​top seat 412, which is not only firm and reliable, but also facilitates quick installation and removal, so that the outer casing 401 and the housing 11 can be detachably connected, which facilitates the maintenance of the equipment and the replacement of parts.

[0034] The container bag 402 is equipped with a pull rope 413, which allows for easy opening and closing of the container bag 402, enabling quick operation while ensuring the container bag 402 remains airtight. Multiple sets of hooks 18 are provided on both sides of the housing 11, and two sets of lifting straps 23 are also provided on the top of the housing 11. The two ends of the lifting straps 23 are connected to the hooks 18, greatly facilitating the handling of the equipment.

[0035] A drawer 24 is provided on one side of the housing 11. The drawer 24 is slidably connected to the housing 11, and the hanging strap 23 can be easily placed in the drawer 24 for convenient storage and retrieval. In addition, a backup battery 34 is also provided inside the housing 11. When the external power supply is unavailable, the backup battery 34 can provide power to the device in a timely manner, ensuring that the device can operate normally in various environments.

[0036] The specific usage and function of this embodiment are as follows:

[0037] In use, first place the organ into the container bag 402, and close the container bag 402 using the pull rope 413 to ensure its airtightness. Engage the snap-on top seat 412 of the outer casing 401 with the snap-on base 17 of the housing 11 to complete the installation of the casing. Connect the pipeline of the micro oxygen generator 31 to the outlet connector 12, the oxygenator 403, and the oxygen flow port 404, and select the appropriate oxygenation method as needed. Simultaneously, connect the centrifugal pump 405 to the pipeline of the container bag 402, the oxygenator 403, and the micro-plug filter 406, and connect the micro-plug filter 406 to the first perfusion fluid flow port 407 or the second perfusion fluid flow port 408 via a connecting pipe. Place an appropriate amount of ice slush in the placement cavity between the container bag 402 and the outer casing 401 to maintain a low-temperature environment. Open the control panel 13, set the relevant parameters, and connect an external 220V power supply via the power supply 14 to power the device, or activate the backup battery 34 when no external power is available. During equipment operation, pressure sensor 409 monitors pressure changes in the connecting pipe in real time, and the data is transmitted to data acquisition connector 16 via wires to keep track of the filling status. Fan 33 operates to accelerate heat dissipation, and semiconductor component 32 regulates the internal temperature.

[0038] When equipment needs to be moved, it can be moved over short distances using the hooks 18 on both sides of the casing 11, and over longer distances using the slings 23 taken out of the drawer 24 and connected to the hooks 18 for moving.

[0039] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. It is obvious to those skilled in the art that this utility model is not limited to the details of the above exemplary embodiments.

Claims

1. A portable cryogenic oxygen-carrying organ transport box, comprising a shell (11) and a cover (21), characterized in that: A miniature oxygen generator (31) is mounted on the housing (11). Two sets of air outlet connectors (12) are provided on the housing (11). The miniature oxygen generator (31) is connected to the two sets of air outlet connectors (12) respectively through connecting pipes. The cover plate (21) is rotatably connected to the housing (11) to form a placement cavity. A storage component is provided in the placement cavity. The storage component includes a sleeve shell (401). A container is provided inside the sleeve shell (401). The container bag (402) and the oxygenator (403) are provided with two sets of oxygen flow ports (404), one set of the air outlet connector (12) is connected to the oxygenator (403), and the other set of the air outlet connector (12) is connected to one set of oxygen flow ports (404); the housing (11) is provided with a control panel (13), and a power supply (14) and a main control board (15) are installed on one side of the housing (11).

2. The portable cryogenic oxygen-carrying organ transporter according to claim 1, characterized in that: The storage assembly also includes a centrifugal pump (405), which is installed on one side of the outer casing (401). One end of the centrifugal pump (405) is connected to the container bag (402) through a pipeline, and the other end is connected to the oxygenator (403) through the pipeline. A micro-plug filter (406) is provided inside the outer casing (401), and the oxygenator (403) is connected to the micro-plug filter (406) through the pipeline.

3. The portable cryogenic oxygen-carrying organ transporter according to claim 2, characterized in that: The container bag (402) is provided with a first infusion fluid outlet (407) and a second infusion fluid outlet (408). The micro-plug filter (406) is connected to the first infusion fluid outlet (407) or the second infusion fluid outlet (408) through a connecting pipe. A pressure sensor (409) is provided on the connecting pipe. A data acquisition connector (16) is provided on the housing (11). The pressure sensor (409) is connected to the data acquisition connector (16) through a wire.

4. The portable cryogenic oxygen-carrying organ transporter according to claim 3, characterized in that: The container bag (402) is provided with a silicone soft film (410), and the silicone soft film (410) has multiple sets of through holes. Both the container bag (402) and the silicone soft film (410) are made of soft material. The outer shell of the package (401) is provided with a support frame (411), and the container bag (402) is clipped on the support frame (411). A placement cavity is formed between the container bag (402) and the outer shell of the package (401), and ice slush is placed in the placement cavity.

5. The portable cryogenic oxygen-carrying organ transporter according to claim 4, characterized in that: A base plate (22) is provided below the housing (11). The base plate (22) is connected to the housing (11) to form an installation cavity. A semiconductor component (32) is provided in the installation cavity. Multiple through slots are opened on one side of the housing (11). The installation cavity is connected to the external environment through the through slots. Multiple fans (33) are provided in the installation cavity. The fans (33) are installed in the through slots.

6. The portable cryogenic oxygen-carrying organ transporter according to claim 1, characterized in that: The housing (11) is provided with a buckle base (17), and the outer casing (401) is provided with a buckle top seat (412) corresponding to the buckle base (17). The buckle base (17) is snapped into the buckle top seat (412), and the outer casing (401) is detachably connected to the housing (11).

7. The portable cryogenic oxygen-carrying organ transporter according to claim 6, characterized in that: The container bag (402) is provided with a drawstring (413), and the container bag (402) can be opened or closed by the drawstring (413); multiple sets of hooks (18) are provided on both sides of the housing (11), and two sets of slings (23) are provided on the top of the housing (11), with the two ends of the slings (23) respectively connected to the hooks (18).

8. The portable cryogenic oxygen-carrying organ transporter according to claim 7, characterized in that: A drawer (24) is provided on one side of the housing (11). The drawer (24) is slidably connected to the housing (11). The sling (23) can be placed in the drawer (24). A spare battery (34) is also provided inside the housing (11).