Cell centrifuge for molecular biology

Abstract

The utility model discloses a cell centrifuge for molecular biology, which comprises a centrifuge shell, a sealing cover plate and a working cavity, a driving mechanism is arranged in the working cavity, a placing mechanism for storing test tubes is arranged on the driving mechanism, a sealing mechanism is arranged on the placing mechanism, and the sealing cover plate is arranged on the sealing mechanism. And a pressing mechanism for pressing the placing mechanism is arranged on the placing mechanism. The placing mechanism can be used for storing test tubes, the placing mechanism is fixedly connected with the driving mechanism to complete the centrifugation step, the placing mechanism can be used for placing and fixing different types of test tubes, and the sealing mechanism can be mounted above the placing mechanism when the centrifugation step is carried out, so that the test tubes can be conveniently and rapidly placed. In this way, material splashing pollution can be prevented when test tube materials are centrifuged, and a downward pressing mechanism can be extruded when a sealing cover plate is closed, so that further reinforcement of the sealing mechanism can be completed, and the sealing mechanism is prevented from being away from the top of the placing mechanism.

Description

Technical Field

[0001] This utility model relates to the field of cell centrifugation device technology, specifically a cell centrifuge for molecular biology. Background Technology

[0002] In molecular biology research, cell centrifuges are an indispensable tool for processing various biological samples, such as cells, viruses, DNA, RNA, and proteins.

[0003] Cell centrifuges can separate suspended cells from the culture medium by centrifuging at different speeds. Generally, lower speeds are sufficient for precipitating most mammalian cells. Furthermore, cell lysis allows for component separation: after cell lysis, organelles, membrane fragments, nuclear material, and other subcellular structures can be separated using differential centrifugation. This involves a series of progressively increasing centrifugal forces to precipitate particles ranging from larger to smaller. Existing centrifuges, when used with a large amount of material in the test tube, are prone to overflowing during start-up and shutdown, leading to cross-contamination. Therefore, we propose a cell centrifuge for molecular biology. Utility Model Content

[0004] The purpose of this invention is to provide a cell centrifuge for molecular biology to solve the problems mentioned in the background art.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a cell centrifuge for molecular biology, comprising a centrifuge housing, with multiple sets of support seats fixedly installed at the bottom of the centrifuge housing, and a sealing cover plate hinged to one side of the top of the centrifuge housing via a hinge seat. A working chamber is provided on the centrifuge housing, and a drive mechanism is provided inside the working chamber. A placement mechanism for storing test tubes is provided on the drive mechanism, a sealing mechanism for preventing splashing of materials inside the test tubes is provided on the placement mechanism, and a pressing mechanism for pressing the placement mechanism is provided on the placement mechanism.

[0006] Furthermore, the driving mechanism includes a fixed frame, a drive motor, and a rotating shaft. The fixed frame is fixedly installed inside the working cavity, the drive motor is fixedly installed at the bottom of the fixed frame, the output end of the drive motor is fixedly connected to the rotating shaft, and a placement mechanism is fixedly installed at the top of the rotating shaft.

[0007] Furthermore, the placement mechanism includes a positioning frame, a placement groove, a placement compartment, an overlapping shaft, and a baffle. The top of the rotating shaft is fixedly installed with a positioning frame, and a placement groove is provided on the positioning frame. Both sides of the placement compartment are fixedly installed with overlapping shafts that overlap inside the placement groove. A baffle that fits against the positioning frame is provided on the outside of the overlapping shaft.

[0008] Furthermore, the sealing mechanism includes a positioning rod, a positioning piece, and a sealing plate. Multiple sets of positioning rods are fixedly installed on the positioning frame. Two sets of positioning grooves adapted to the positioning rods are opened through the sealing plate. Through grooves are opened through the sealing plate at the positions corresponding to the other two sets of positioning rods. The top of the positioning rod is rotatably connected to a positioning piece that fits against the top of the sealing plate.

[0009] Furthermore, the pressing mechanism includes a fixed tube, a telescopic rod, a ball bearing, and a compression spring. The fixed tube is fixedly installed on the top of the sealing plate, the telescopic rod is slidably connected inside the fixed tube, the ball bearing is rotatably connected to the top of the telescopic rod, and a compression spring is fixedly installed at the bottom of the telescopic rod. The bottom of the compression spring is fixedly installed on the inner wall of the fixed tube.

[0010] Furthermore, a sealing gasket is fixedly installed on one side of the sealing cover plate at the position corresponding to the working cavity, and a buffer pad made of rubber material is provided at the bottom of the sealing plate.

[0011] Compared with the prior art, the present invention has the following advantages: The placement mechanism of the present invention can store test tubes, and the placement mechanism is fixedly connected to the drive mechanism. In this way, the rotation of the drive mechanism can drive the placement mechanism to rotate quickly, thereby completing the centrifugation step. The placement mechanism can place and fix test tubes of different sizes. During the centrifugation step, the sealing mechanism can be installed above the placement mechanism to prevent material splashing and contamination during centrifugation. When the sealing cover is closed, the pressing mechanism can be squeezed to further reinforce the sealing mechanism and prevent the sealing mechanism from moving away from the top of the placement mechanism. Attached Figure Description

[0012] Figure 1 This is a three-dimensional structural schematic diagram of the present utility model;

[0013] Figure 2 This is a three-dimensional structural schematic diagram of the driving mechanism, placement mechanism and sealing mechanism of this utility model;

[0014] Figure 3 This is a three-dimensional structural diagram of the pressing mechanism of this utility model.

[0015] In the diagram: 1 Centrifuge housing, 2 Support base, 3 Hinge base, 4 Sealing cover, 5 Working chamber, 6 Drive mechanism, 7 Placement mechanism, 8 Sealing mechanism, 9 Pressing mechanism, 10 Fixing frame, 11 Drive motor, 12 Rotating shaft, 13 Positioning frame, 14 Placement slot, 15 Placement chamber, 16 Overlapping shaft, 17 Baffle, 18 Positioning rod, 19 Positioning slot, 20 Through slot, 21 Positioning piece, 22 Sealing plate, 23 Fixing tube, 24 Telescopic rod, 25 Ball bearing, 26 Compression spring, 27 Sealing gasket. Detailed Implementation

[0016] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0017] Please see Figures 1-3 This utility model provides a technical solution: a cell centrifuge for molecular biology, including a centrifuge housing 1, with multiple sets of support seats 2 fixedly installed at the bottom of the centrifuge housing 1, and a sealing cover plate 4 hinged to one side of the top of the centrifuge housing 1 via a hinge seat 3. A working chamber 5 is provided on the centrifuge housing 1, and a drive mechanism 6 is provided inside the working chamber 5. A placement mechanism 7 for storing test tubes is provided on the drive mechanism 6, a sealing mechanism 8 for preventing splashing of materials inside the test tubes is provided on the placement mechanism 7, and a pressing mechanism 9 for pressing the placement mechanism 7 is provided on the placement mechanism 7.

[0018] The placement mechanism 7 is designed to store test tubes and is fixedly connected to the drive mechanism 6. The rotation of the drive mechanism 6 can drive the placement mechanism 7 to rotate rapidly, thereby completing the centrifugation step. The placement mechanism 7 can hold and fix test tubes of different sizes. During the centrifugation step, the sealing mechanism 8 can be installed above the placement mechanism 7 to prevent material splashing and contamination during centrifugation. When the sealing cover 4 is closed, the pressing mechanism 9 can be squeezed to further reinforce the sealing mechanism 8 and prevent it from moving away from the top of the placement mechanism 7.

[0019] Please see Figure 1 , Figure 2 and Figure 3 The drive mechanism 6 includes a fixed frame 10, a drive motor 11, and a rotating shaft 12. The fixed frame 10 is fixedly installed inside the working cavity 5. The drive motor 11 is fixedly installed at the bottom of the fixed frame 10. The output end of the drive motor 11 is fixedly connected to the rotating shaft 12. The top of the rotating shaft 12 is fixedly installed with a placement mechanism 7.

[0020] When a centrifugation step is required, the drive motor 11 operates, driving the rotating shaft 12 and the placement mechanism 7 to rotate rapidly, thus centrifuging the material inside the placement mechanism 7.

[0021] Please see Figure 1 , Figure 2 and Figure 3 The placement mechanism 7 includes a positioning frame 13, a placement groove 14, a placement chamber 15, an overlapping shaft 16, and a baffle 17. The positioning frame 13 is fixedly installed on the top of the rotating shaft 12. The positioning frame 13 has a placement groove 14. The overlapping shafts 16, which overlap inside the placement grooves 14, are fixedly installed on both sides of the placement chamber 15. The baffle 17, which fits against the positioning frame 13, is provided on the outside of the overlapping shaft 16.

[0022] When it is necessary to place test tubes of different specifications for centrifugation, the corresponding placement chamber 15 is selected, the overlapping shafts 16 on both sides of the placement chamber 15 are overlapped inside the placement groove 14, and the two sets of baffles 17 are in contact with and attached to the positioning frame 13, thereby completing the placement of the placement chambers 15 of different specifications.

[0023] Please see Figure 1 , Figure 2 and Figure 3 The sealing mechanism 8 includes a positioning rod 18, a positioning piece 21, and a sealing plate 22. Multiple sets of positioning rods 18 are fixedly installed on the positioning frame 13. Two sets of positioning grooves 19 adapted to the positioning rods 18 are opened through the sealing plate 22. Through grooves 20 are opened through the sealing plate 22 at the positions corresponding to the other two sets of positioning rods 18. The top of the positioning rod 18 is rotatably connected to the positioning piece 21 that fits against the top of the sealing plate 22.

[0024] When the sealing plate 22 needs to be placed, two sets of positioning rods 18 are first inserted into the positioning groove 19 to prevent the sealing plate 22 from shaking. The other two sets of positioning rods 18 and positioning pieces 21 pass through the two through grooves 20. Then, by rotating the positioning pieces 21, the positioning pieces 21 can overlap the top of the sealing plate 22, so that the sealing plate 22 can be tightly attached to the top of the placement chamber 15.

[0025] Please see Figure 1 , Figure 2 and Figure 3 The pressing mechanism 9 includes a fixed tube 23, a telescopic rod 24, a ball bearing 25, and a compression spring 26. A sealing gasket 27 is fixedly installed on one side of the sealing cover plate 4 and at the position corresponding to the working chamber 5. A fixed tube 23 is fixedly installed on the top of the sealing plate 22. A telescopic rod 24 is slidably connected inside the fixed tube 23. A ball bearing 25 is rotatably connected to the top of the telescopic rod 24. A compression spring 26 is fixedly installed at the bottom of the telescopic rod 24. The bottom of the compression spring 26 is fixedly installed on the inner wall of the fixed tube 23.

[0026] When the sealing cover 4 flips down, the sealing gasket 27 first contacts the ball 25, and then the ball 25 squeezes the telescopic rod 24 to descend along the inside of the fixed tube 23. This setting allows the telescopic rod 24 to squeeze the compression spring 26, which in turn squeezes the fixed tube 23, thereby preventing the sealing plate 22 from pushing against the surface of the placement chamber 15.

[0027] Please see Figure 1 and Figure 2 The bottom of the sealing plate 22 is provided with a buffer pad made of rubber material. The buffer pad at the bottom of the sealing plate 22 can prevent the sealing plate 22 from being squeezed hard and causing damage to the placement chamber 15.

[0028] In use, the placement mechanism 7 stores test tubes and is fixedly connected to the drive mechanism 6. The rotation of the drive mechanism 6 causes the placement mechanism 7 to rotate rapidly, thus completing the centrifugation step. The placement mechanism 7 can hold and fix test tubes of different sizes. During centrifugation, a sealing mechanism 8 can be installed above the placement mechanism 7 to prevent material splashing and contamination during centrifugation. When the sealing cover 4 is closed, the pressing mechanism 9 is squeezed, further reinforcing the sealing mechanism 8 and preventing it from moving away from the top of the placement mechanism 7. When centrifugation is required, the drive motor 11 operates, causing the rotating shaft 12 and the placement mechanism 7 to rotate rapidly, thus centrifuging the material inside the placement mechanism 7. When centrifuging test tubes of different sizes, the corresponding placement chamber 15 is selected. The overlapping shafts 16 on both sides of the compartment 15 overlap with the inside of the placement groove 14, and the two sets of baffles 17 are in contact with the positioning frame 13 to complete the placement of different specifications of the compartment 15. When the sealing plate 22 needs to be placed, firstly, two sets of positioning rods 18 will be inserted into the inside of the positioning groove 19, which can prevent the sealing plate 22 from shaking. The other two sets of positioning rods 18 and positioning pieces 21 will pass through two sets of through grooves 20. Then, by rotating the positioning piece 21, the positioning piece 21 can overlap the top of the sealing plate 22, so that the sealing plate 22 can be tightly attached to the top of the compartment 15. When the sealing cover 4 flips down, the sealing gasket 27 will first contact the ball 25. Then the ball 25 will squeeze the telescopic rod 24 and descend along the inside of the fixed tube 23. This setting can use the telescopic rod 24 to squeeze the compression spring 26, which can squeeze the fixed tube 23, thereby preventing the sealing plate 22 from pushing against the surface of the compartment 15.

[0029] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A cell centrifuge for molecular biology, comprising a centrifuge housing (1), wherein a plurality of support seats (2) are fixedly installed at the bottom of the centrifuge housing (1), and a sealing cover plate (4) is hinged to one side of the top of the centrifuge housing (1) via a hinge seat (3), characterized in that: The centrifuge housing (1) has a working chamber (5), and a drive mechanism (6) is provided inside the working chamber (5). The drive mechanism (6) is provided with a placement mechanism (7) for storing test tubes. The placement mechanism (7) is provided with a sealing mechanism (8) to prevent the material inside the test tube from splashing. The placement mechanism (7) is provided with a pressing mechanism (9) to press the placement mechanism (7).

2. The cell centrifuge for molecular biology according to claim 1, characterized in that: The drive mechanism (6) includes a fixed frame (10), a drive motor (11) and a rotating shaft (12). The fixed frame (10) is fixedly installed inside the working cavity (5). The drive motor (11) is fixedly installed at the bottom of the fixed frame (10). The rotating shaft (12) is fixedly connected to the output end of the drive motor (11). The placement mechanism (7) is fixedly installed at the top of the rotating shaft (12).

3. A cell centrifuge for molecular biology according to claim 2, characterized in that: The placement mechanism (7) includes a positioning frame (13), a placement groove (14), a placement compartment (15), an overlapping shaft (16), and a baffle (17). The top of the rotating shaft (12) is fixedly installed with the positioning frame (13). The positioning frame (13) is provided with a placement groove (14). The two sides of the placement compartment (15) are fixedly installed with overlapping shafts (16) that overlap inside the placement groove (14). The outside of the overlapping shaft (16) is provided with a baffle (17) that fits against the positioning frame (13).

4. A cell centrifuge for molecular biology according to claim 3, characterized in that: The sealing mechanism (8) includes a positioning rod (18), a positioning piece (21), and a sealing plate (22). Multiple sets of positioning rods (18) are fixedly installed on the positioning frame (13). Two sets of positioning grooves (19) adapted to the positioning rods (18) are opened through the sealing plate (22). Through grooves (20) are opened through the sealing plate (22) corresponding to the positions of the other two sets of positioning rods (18). The top of the positioning rod (18) is rotatably connected to a positioning piece (21) that fits against the top of the sealing plate (22).

5. A cell centrifuge for molecular biology according to claim 4, characterized in that: The pressing mechanism (9) includes a fixed tube (23), a telescopic rod (24), a ball bearing (25), and a compression spring (26). The fixed tube (23) is fixedly installed on the top of the sealing plate (22). The telescopic rod (24) is slidably connected inside the fixed tube (23). The ball bearing (25) is rotatably connected to the top of the telescopic rod (24). The compression spring (26) is fixedly installed at the bottom of the telescopic rod (24). The bottom of the compression spring (26) is fixedly installed on the inner wall of the fixed tube (23).

6. A cell centrifuge for molecular biology according to claim 5, characterized in that: A sealing gasket (27) is fixedly installed on one side of the sealing cover plate (4) and at the position corresponding to the working cavity (5), and a buffer pad made of rubber material is provided at the bottom of the sealing plate (22).

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