Cooling device of biological reaction equipment

By designing cooling and drive components, utilizing condensers and serpentine tubes to circulate cooling water, combined with rotating fan blades to blow air, the problem of traditional cooling devices affecting cell culture has been solved, achieving efficient cooling and stable cell growth in the bioreactor.

CN223879750UActive Publication Date: 2026-02-06BIOTECH BIOTECHNOLOGY (CHENGDU) CO LTD
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Patent Information

Application Number
CN202422921119.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-11-28
Publication Date
2026-02-06
Estimated Expiration
2034-11-28

AI Technical Summary

Technical Problem

Traditional cooling devices in bioreactors affect cell culture results and cannot effectively control heat release, resulting in a high-temperature environment that is detrimental to cell growth.

Method used

The design employs a combination of cooling and drive components, using a condenser and serpentine tube to circulate cooling water, combined with a rotating fan blade to blow air, to achieve all-round cooling of the bioreactor.

Benefits of technology

This technology enables efficient cooling of the bioreactor, ensuring the stability of the cell culture environment and improving the effectiveness of cell growth.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a cooling device of biological reaction equipment, which comprises an assembly seat, the top of the assembly seat penetrates through and is fixedly connected with an assembly insertion shell, a plurality of assembly holes are arranged at the bottom in the assembly insertion shell, a bioreactor is arranged above the assembly seat, the side wall of the assembly seat is fixedly connected with a storage box, and the storage box is arranged in the assembly insertion shell. The side wall of the storage box is fixedly connected with a water inlet pipe and a water outlet pipe. According to the utility model, the second bevel gear drives the driving rotating shaft on the first bevel gear and the second driving transmission disc to rotate, and then the second driving transmission disc drives the driving worm on the first driving transmission disc to rotate through the belt; the driving worm is convenient to drive, mounting rotating shafts and mounting fan blades on a plurality of mounting worm wheels are also driven to rotate and blow air, so that the air is cooled by a coiled pipe and conducts and cools the bioreactor through a plurality of assembly holes in an assembly insertion shell, heat release is fully controlled, and the use effect is improved.
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Description

TECHNICAL FIELD

[0001] The utility model relates to biological reactor technical field especially relates to a cooling device of biological reaction equipment. BACKGROUND

[0002] Biological reactor usually provides the environment suitable for cell growth for cell culture process, and the cell culture process usually involves assimilation and dissimilation of organisms, and the cell culture process needs to absorb energy from the surrounding environment in assimilation, and releases energy to the surrounding environment in dissimilation, and usually the energy released in dissimilation is more than the energy absorbed in assimilation, and the excess energy is in the form of heat, and at the same time, cooling device is needed for energy release, and high temperature environment is usually not conducive to the smooth progress of cell culture process, and the traditional cooling device releases heat to the biological reactor, mostly through cold water for heat exchange and controls the growth environment of cells in the biological reactor, which affects the culture of cells and is very troublesome, thereby reducing the use effect. SUMMARY

[0003] The utility model discloses a cooling device of biological reaction equipment to solve the shortcoming of prior art.

[0004] In order to achieve the above-mentioned purpose, the utility model discloses a cooling device of biological reaction equipment, which comprises an assembly seat, the assembly seat top penetrates and is fixedly connected with assembly insert shell, a plurality of assembly holes are formed in the bottom of the assembly insert shell, the assembly seat top is provided with a biological reactor, the assembly seat side wall is fixedly connected with a storage tank, the storage tank side wall is fixedly connected with a water inlet pipe and a drain pipe, the water inlet pipe side wall is connected with a water inlet valve, the drain pipe side wall is connected with a drain valve, and the storage tank surface is connected with a cooling assembly.

[0005] The installation support is fixedly connected between the two sides of the inner side wall of the assembly seat, the top of the installation support penetrates and is rotatably connected with a plurality of installation rotating shafts, the two ends of the installation rotating shaft are fixedly connected with an installation worm wheel and an installation fan blade respectively, and the assembly seat side wall is connected with a driving assembly.

[0006] The installation support is fixedly connected between the two sides of the inner side wall of the assembly seat, the top of the installation support penetrates and is rotatably connected with a plurality of installation rotating shafts, the two ends of the installation rotating shaft are fixedly connected with an installation worm wheel and an installation fan blade respectively, and the assembly seat side wall is connected with a driving assembly.

[0007] As a further description of the above technical scheme:

[0008] The cooling assembly comprises a first branch pipe fixedly connected with the surface of the storage tank, the first branch pipe tail end is fixedly connected with a water pump, the water pump water outlet is fixedly connected with a second branch pipe, and the second branch pipe outer side wall is fixedly sleeved with a condenser.

[0009] As a further description of the above technical scheme:

[0010] The second branch pipe end penetrates the assembly seat and is fixedly connected with a serpentine pipe, and the serpentine pipe end penetrates the assembly seat and is fixedly connected with the storage tank and communicates with the storage tank.

[0011] As a further description of the above technical solution:

[0012] The driving assembly comprises a driving worm penetrating and rotationally connected with the side wall of the assembly seat, one end of the driving worm is rotationally connected with the inner wall of the assembly seat, and the other end of the driving worm is fixedly connected with a first driving transmission disc.

[0013] As a further description of the above technical solution:

[0014] A plurality of the mounting worm gears are meshingly connected with the driving worm, a driving shaft is rotationally connected with the side wall of the assembly seat, a first bevel gear is fixedly connected with the end of the driving shaft, and a second driving transmission disc is fixedly sleeved with the outer side wall of the driving shaft.

[0015] As a further description of the above technical solution:

[0016] The second driving transmission disc is drivingly connected with the first driving transmission disc through a belt, two driving support plates are fixedly connected with the side wall of the assembly seat, a driving motor is fixedly connected with the surface of one of the driving support plates, and a driving rod is fixedly connected with the output end of the driving motor.

[0017] As a further description of the above technical solution:

[0018] The end of the driving rod penetrates one of the driving support plates and is rotationally connected with the other driving support plate,

[0019] A second bevel gear is fixedly sleeved with the outer side wall of the driving rod, and the second bevel gear is meshingly connected with the first bevel gear.

[0020] The utility model has the advantages of the following beneficial effects:

[0021] The first branch pipe, the water pump, the second branch pipe, the condenser and the serpentine pipe are matched by the cooling assembly, water inside the second branch pipe is cooled by the condenser, cold water passes through the serpentine pipe and is discharged into the storage tank, cold air conducted by the serpentine pipe is stored in the assembly seat, then the cold air passes through the assembly insert shell and is used for circulating cooling of the bioreactor, the driving worm, the first driving transmission disc, the driving shaft, the first bevel gear, the second driving transmission disc, the driving support plate, the driving motor, the driving rod and the second bevel gear are matched by the driving assembly, the second bevel gear on the driving rod is rotated by the driving motor, then the driving shaft and the second driving transmission disc on the first bevel gear are rotated by the second bevel gear, the driving worm on the first driving transmission disc is rotated by the second driving transmission disc through the belt, the installation shaft and the installation fan blade on the plurality of installation worm gears are rotated by the driving worm, air is cooled by the serpentine pipe and is used for conducting cooling of the bioreactor through the assembly insert shell, the release of heat is sufficiently controlled, and therefore the use effect is improved. BRIEF DESCRIPTION OF DRAWINGS

[0022] Fig. 1 is a whole structure schematic view of the cooling device of the bioreactor equipment;

[0023] Fig. 2 is an internal structure schematic view of the assembly seat and the assembly insert shell of the cooling device of the bioreactor equipment;

[0024] Fig. 3 is an enlarged structure schematic view of A in Fig. 1.

[0025] Legend:

[0026] 1, assembly seat; 2, assembly insert shell; 3, bioreactor; 4, storage tank; 5, water inlet pipe; 6,

[0027] drain pipe; 7, first branch pipe; 8, water pump; 9, second branch pipe; 10, condenser; 11, serpentine pipe; 12, mounting bracket; 13, installation shaft; 14, installation worm gear; 15, installation fan blade; 16, driving worm; 17, first driving transmission disc; 18, driving shaft; 19, first bevel gear; 20, second driving transmission disc; 21, driving support plate; 22, driving motor; 23, driving rod; 24, second bevel gear. DETAILED DESCRIPTION

[0028] Clearly, the described embodiments are merely a part of the embodiments of the present utility model, rather than all the embodiments. Based on the embodiments in the present utility model, all the other embodiments obtained by the ordinary skilled in the art without making creative labor belong to the scope of protection of the present utility model.

[0029] With reference to FIGS. 1-3, the cooling device of the biological reaction equipment provided by the present utility model comprises an assembly seat 1, the top of the assembly seat 1 is penetrated and fixedly connected with an assembly plug shell 2, a plurality of assembly holes are formed in the inner bottom of the assembly plug shell 2, a biological reactor 3 is arranged above the assembly seat 1, a storage tank 4 is fixedly connected to the side wall of the assembly seat 1, a water inlet pipe 5 and a drain pipe 6 are fixedly connected to the side wall of the storage tank 4, water inlet valves are connected to the side wall of the water inlet pipe 5, a water outlet valve is connected to the side wall of the drain pipe 6, a cooling assembly is connected to the surface of the storage tank 4, the cooling assembly plays a role of conducting cooling to the biological reactor 3 through cooling, the cooling assembly comprises a first branch pipe 7 fixedly connected to the surface of the storage tank 4, a water pump 8 is fixedly connected to the tail end of the first branch pipe 7, a second branch pipe 9 is fixedly connected to the water outlet of the water pump 8, a condenser 10 is fixedly sleeved to the outer side wall of the second branch pipe 9, a serpentine pipe 11 is penetrated through the assembly seat 1 and fixedly connected to the tail end of the second branch pipe 9, the tail end of the serpentine pipe 11 is penetrated through the assembly seat 1 and fixedly connected and communicated with the storage tank 4, the condenser 10 plays a role of driving water to be cooled.

[0030] A mounting bracket 12 is fixedly connected between the two sides of the inner side wall of the assembly seat 1, a plurality of mounting rotating shafts 13 are penetrated through and rotatably connected to the top of the mounting bracket 12, a mounting worm gear 14 and a mounting fan blade 15 are fixedly connected to the two ends of the mounting rotating shaft 13 respectively, a driving assembly is connected to the side wall of the assembly seat 1, the driving assembly comprises a driving motor 16 penetrated through and rotatably connected to the side wall of the assembly seat 1, a driving belt 17 is fixedly sleeved to the outer side wall of the driving motor 16, the driving belt 17 is fixedly sleeved to the outer side wall of the mounting rotating shaft 13, and the driving motor 16 drives the mounting worm gear 14 to rotate through the driving belt 17.

[0031] A drive worm 16 is connected to the side wall of the assembly seat 1, one end of the drive worm 16 is rotatably connected to the inner wall of the assembly seat 1, the other end of the drive worm 16 is fixedly connected with a first drive transmission disc 17, a plurality of installation worm gears 14 are all meshingly connected with the drive worm 16, a drive shaft 18 is rotatably connected to the side wall of the assembly seat 1, a first bevel gear 19 is fixedly connected to the tail end of the drive shaft 18, a second drive transmission disc 20 is fixedly sleeved on the outer side wall of the drive shaft 18, the second drive transmission disc 20 is drivingly connected with the first drive transmission disc 17 through a belt, two drive support plates 21 are fixedly connected to the side wall of the assembly seat 1, the surface of one of the drive support plates 21 is fixedly connected with a drive motor 22, the output end of the drive motor 22 is fixedly connected with a drive rod 23, the tail end of the drive rod 23 penetrates through the one drive support plate 21 and is rotatably connected with the other drive support plate 21, a second bevel gear 24 is fixedly sleeved on the outer side wall of the drive rod 23, the second bevel gear 24 is meshingly connected with the first bevel gear 19, and the drive motor 22 plays a role of driving the drive rod 23 to rotate.

[0032] Working principle: in use, first start the water pump 8, drive the first branch pipe 7 to extract the water in the storage box 4 through the water pump 8, so that the water flows through the first branch pipe 7 and enters the second branch pipe 9, and at the same time, start the condenser 10 on the first branch pipe 7 to cool the water, then the cooled water enters the coiled pipe 11, and at the same time, the cold air is conducted into the assembly seat 1 through the coiled pipe 11, then the cold air is conducted and cooled to the bioreactor 3 through the plurality of assembly holes on the assembly shell 2, so as to control the heat emitted in the bioreactor 3, then the cooled water flows through the coiled pipe 11 and enters the storage box 4, so as to circularly conduct and cool the bioreactor 3, and ensure the circulating cooling effect.

[0033] Then start the drive motor 22, drive the second bevel gear 24 on the drive rod 23 to rotate through the drive motor 22, then the second bevel gear 24 also drives the drive shaft 18 and the second drive transmission disc 20 on the first bevel gear 19 to rotate, then the second drive transmission disc 20 drives the drive worm 16 on the first drive transmission disc 17 to rotate through the belt, so that the drive worm 16 drives the plurality of installation worm gears 14 to rotate, then the installation worm gears 14 also drive the installation fan blades 15 on the installation shaft 13 to rotate and blow, so that the wind cools through the coiled pipe 11, so as to accelerate the cold air to be conducted and cooled to the bioreactor 3 through the plurality of assembly holes on the assembly shell 2, and ensure the further cooling effect.

[0034]

[0035] ​Finally, it should be noted that: the above only for the preferred embodiments of the present application, and is not intended to limit the present application, although the foregoing embodiments of the present application has been described in detail, for the skilled in the art, it still can be modified, or for part of the technical features of the equivalent replacement, the spirit and principles of the present application, made any modification, equivalent replacement, improvement, etc., should be included within the scope of the present application.

Claims

1. Cooling device for a bioreactor, comprising a mounting seat (1), characterized in that: The assembly seat (1) top through and fixedly connected with assembly plug shell (2), the assembly plug shell (2) inside bottom is provided with a plurality of assembly holes, the assembly seat (1) above is provided with a bioreactor (3), the assembly seat (1) side wall is fixedly connected with the storage tank (4), the storage tank (4) side wall is fixedly connected with water inlet pipe (5) and drain pipe (6), the water inlet pipe (5) side wall is connected with water inlet valve, the drain pipe (6) side wall is connected with drain valve, the storage tank (4) surface is connected with cooling assembly; The assembly seat (1) inside wall between the two sides is fixedly connected with the mounting bracket (12), the mounting bracket (12) top through and rotatably connected with a plurality of mounting shaft (13), the mounting shaft (13) both ends are fixedly connected with mounting worm (14) and mounting fan blade (15), the assembly seat (1) side wall is connected with drive assembly.

2. A cooling device for a bioreactor according to claim 1, characterized in that: The cooling assembly includes a first branch pipe (7) fixedly connected with the storage tank (4), the first branch pipe (7) end is fixedly connected with a water pump (8), the water pump (8) outlet is fixedly connected with a second branch pipe (9), the second branch pipe (9) outer side wall is fixedly sleeved with a condenser (10).

3. A cooling device for a bioreactor according to claim 2, wherein: The second branch pipe (9) end through the assembly seat (1) and fixedly connected with a serpentine tube (11), the serpentine tube (11) end through the assembly seat (1) and fixedly connected with the storage tank (4).

4. The cooling device for a bioreactor according to claim 1, wherein: The drive assembly includes a drive worm (16) rotatably connected through the assembly seat (1) side wall, one end of the drive worm (16) is rotatably connected with the assembly seat (1) inner wall, the other end of the drive worm (16) is fixedly connected with a first drive transmission disc (17).

5. A cooling device for a bioreactor according to claim 4, wherein: A plurality of mounting worm (14) are rotatably connected with the drive worm (16), the assembly seat (1) side wall is rotatably connected with a drive shaft (18), the drive shaft (18) end is fixedly connected with a first bevel gear (19), the drive shaft (18) outer side wall is fixedly sleeved with a second drive transmission disc (20).

6. A cooling device for a bioreactor according to claim 5, wherein: The second drive transmission disc (20) is drivingly connected with the first drive transmission disc (17) through a belt, the assembly seat (1) side wall is fixedly connected with two drive support plates (21), one of the drive support plates (21) surface is fixedly connected with a drive motor (22), the drive motor (22) output end is fixedly connected with a drive rod (23).

7. A cooling device for a bioreactor according to claim 6, wherein: The drive rod (23) end through one of the drive support plates (21) and rotatably connected with the other drive support plate (21), the drive rod (23) outer side wall is fixedly sleeved with a second bevel gear (24), the second bevel gear (24) is rotatably connected with the first bevel gear (19).