Improved enzyme preparation sterile filtering device

Abstract

The utility model discloses an improved enzyme preparation sterile filtering device, which relates to the field of enzyme preparation filtering, and comprises a fixing frame, a filtering structure is fixedly connected in the fixing frame, the filtering structure comprises two groups of single-group filter cartridges, and the number of the single-group filter cartridges is two. In the preparation and purification process of the enzyme preparation, the device can meet filtering operation with different precision requirements, the core is a unique filtering structure, the device has flexible layered filtering capacity, and the filtering level can be easily adjusted according to the actual production requirement so as to realize accurate purification of the enzyme preparation. In addition, an extra filter material is arranged in the liquid outlet pipeline in the device, a user only needs to simply screw a valve in the pipeline, the filtering speed and the fine degree can be regulated and controlled at will, the design is easy and convenient to operate, the filtering efficiency and flexibility are greatly improved, and powerful support is provided for industrial production of enzyme preparations.

Description

TECHNICAL FIELD

[0001] The utility model relates to enzyme preparation filtering field, concretely is a kind of improved enzyme preparation sterile filtering device. BACKGROUND

[0002] Enzyme preparation filtering refers to the process of separating solid impurities (such as bacteria, cell fragments, protein precipitates, etc.) in fermentation broth, cell disruption liquid or enzyme extraction liquid during enzyme preparation production from target enzyme liquid through physical separation technology.

[0003] The existing enzyme preparation filter cartridge on the current market generally has limitations in design, and the core problem is the single filtration structure. Most filter cartridges only have a fixed mode of filter layer (such as a single pore size microfiltration membrane or ultrafiltration membrane) built-in. This design makes it impossible for users to flexibly adjust the filtration precision according to actual production needs.

[0004] For example, when separating large particle impurities from crude enzyme liquid, the fixed pore size filter layer may reduce the recovery rate due to insufficient interception efficiency; and when further purifying enzyme liquid, the large pore size may cause the loss of target enzyme molecules. This functional defect limits the refinement and efficiency of enzyme preparation filtering process, making it difficult to meet the needs of multiple scene applications. SUMMARY

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical scheme: an improved enzyme preparation sterile filtering device, comprising a fixed frame, the fixed frame is internally fixedly connected with a filter structure, the filter structure comprises a single filter cartridge, the single filter cartridge is provided with two groups, and the bottom end of the two groups of single filter cartridges is fixedly connected with a liquid outlet pipeline.

[0006] Preferably, the fixed frame includes a frame body, the frame body is fixedly connected with a climbing ladder on the inside front side, and the frame body is fixedly connected with a fixed table top at the top end inside.

[0007] Preferably, the single filter cartridge includes a filter cartridge cover, the filter cartridge cover is fixedly connected with a filter cartridge body at the bottom end by means of bolts, the filter cartridge body outer wall is fixedly connected with a connecting piece, and the connecting piece is provided with four groups and symmetrically fixed on the outer wall of the filter cartridge body around.

[0008] Preferably, the liquid outlet pipeline comprises a first liquid outlet pipe, one end of the first liquid outlet pipe is fixedly connected with the outside of the single set of filter cartridges located on the left side, a first inlet pipe and a second inlet pipe are fixedly connected to the outer wall of one end of the first liquid outlet pipe, one end of the first inlet pipe is fixedly connected with the outside of the single set of filter cartridges located on the right side, one end of the second inlet pipe is fixedly connected with the bottom end of the single set of filter cartridges located on the right side, a third inlet pipe is fixedly connected to the outer wall of the second inlet pipe, one end of the third inlet pipe is fixedly connected with the second liquid outlet pipe, one end of the second liquid outlet pipe is fixedly connected with the bottom end of the single set of filter cartridges located on the left side, and a connecting pipe is fixedly connected between the second liquid outlet pipe and the first liquid outlet pipe.

[0009] Preferably, the first inlet pipe, the second inlet pipe, the third inlet pipe, the second liquid outlet pipe and the connecting pipe are internally provided with valves.

[0010] Compared with the prior art, the beneficial effects of the present application are:

[0011] The improved enzyme preparation sterile filtration device provided by the present application can meet the filtering operation requirements of different precision during the preparation and purification of enzyme preparation, and the core lies in the unique filtering structure, which has flexible layered filtering capacity, and can easily adjust the filtering level according to actual production needs, so as to realize accurate purification of enzyme preparation. It is worth mentioning that the internal of the liquid outlet pipeline of the device is provided with additional filter material, and the user can control the filtering speed and fineness at will by simply twisting the valve in the pipeline. This design not only is simple and convenient to operate, but also greatly improves the filtering efficiency and flexibility, and provides strong support for the industrialized production of enzyme preparation. BRIEF DESCRIPTION OF DRAWINGS

[0012] The present application will be further described below in combination with the drawings:

[0013] Figure 1 The structure of the present application is shown in the schematic diagram;

[0014] Figure 2 The structure of the present application is shown in the schematic diagram; Figure 1 The structure of the present application is shown in the schematic diagram;

[0015] Figure 3 The filtering structure of the present application is shown in the schematic diagram; Figure 1 ;

[0016] Figure 4 The filtering structure of the present application is shown in the schematic diagram; Figure 2 .

[0017] As shown in the figure: 1, fixed frame; 11, frame body; 12, climbing ladder; 13, fixed table top; 2, filter structure; 21, single group filter cartridge; 211, filter cartridge cover; 212, filter cartridge body; 213, connecting piece; 22, liquid outlet pipeline; 221, first liquid outlet pipe; 222, first inlet pipe; 223, second inlet pipe; 224, third inlet pipe; 225, second liquid outlet pipe; 226, connecting pipe. DETAILED DESCRIPTION

[0018] In order to more clearly illustrate the overall concept of the utility model, the following will be combined with the drawings in the specification to illustrate in detail.

[0019] Please refer to Figures 1 to 4 The utility model provides a technical scheme: an improved enzyme preparation sterile filter device, including fixed frame 1, fixed frame 1 inside fixedly connected with filter structure 2, filter structure 2 includes single group filter cartridge 21, single group filter cartridge 21 is equipped with two groups, and two groups of single group filter cartridge 21 bottom fixedly connected with liquid outlet pipeline 22;

[0020] The device can meet the filtering operation of different precision requirements in the preparation and purification process of enzyme preparation, and the core lies in its unique filter structure 2, which has flexible layered filtering capacity, and can easily adjust the filtering level according to actual production needs, so as to realize accurate purification of enzyme preparation. It is worth mentioning that the additional filter material is built-in in the liquid outlet pipeline 22 in the device, and the user only needs to simply twist the valve in the pipeline to freely control the filtering speed and fineness. This design not only is simple in operation, but also greatly improves the filtering efficiency and flexibility, and provides strong support for the industrial production of enzyme preparation.

[0021] The fixed frame 1 includes the frame body 11, the frame body 11 is internally fixedly connected with the climbing ladder 12 on the front side, and the frame body 11 is internally fixedly connected with the fixed table top 13 on the top end.

[0022] When in use, the user can climb up into the fixed table top 13 through the climbing ladder 12, and conveniently open the single group filter cartridge 21 to place raw materials.

[0023] The single group filter cartridge 21 includes the filter cartridge cover 211, the filter cartridge cover 211 is fixedly connected with the filter cartridge body 212 at the bottom end by means of bolts, the filter cartridge body 212 is fixedly connected with the connecting piece 213 on the outer wall, and the connecting piece 213 is symmetrically fixed on the outer wall of the filter cartridge body 212.

[0024] The filter cartridge body 212 is internally provided with ceramic filter material and metal filter material, the metal filter material is used for coarse filtration or pre-filtration, removes large particle impurities, can adopt laser punching technology to manufacture micron level pore size, and improves the filtration precision; the ceramic filter material is used for clarification filtration of enzyme preparation, especially in the scene requiring high temperature sterilization, the ceramic filter material surface is coated with a polymer layer, which improves the overall hydrophilicity and reduces enzyme adsorption loss;

[0025] The liquid outlet pipeline 22 includes a first liquid outlet pipe 221, one end of the first liquid outlet pipe 221 is fixedly connected to the outside of the single set of filter cartridges 21 located on the left side, a first inlet pipe 222 and a second inlet pipe 223 are fixedly connected to the outer wall of one end of the first liquid outlet pipe 221, one end of the first inlet pipe 222 is fixedly connected to the outside of the single set of filter cartridges 21 located on the right side, one end of the second inlet pipe 223 is fixedly connected to the bottom end of the single set of filter cartridges 21 located on the right side, the second inlet pipe 223 is fixedly connected with a third inlet pipe 224 on the outer wall, one end of the third inlet pipe 224 is fixedly connected with a second liquid outlet pipe 225, one end of the second liquid outlet pipe 225 is fixedly connected to the bottom end of the single set of filter cartridges 21 located on the left side, and a connecting pipe 226 is fixedly connected between the second liquid outlet pipe 225 and the first liquid outlet pipe 221;

[0026] Valves are installed in the first inlet pipe 222, the second inlet pipe 223, the third inlet pipe 224, the second liquid outlet pipe 225 and the connecting pipe 226;

[0027] When simple filtration is performed, all valves except the first inlet pipe 222 can be tightened, at this time the filter cartridge cover 211 is opened and enzyme preparation raw materials are put in, the enzyme preparations in the two groups of single set of filter cartridges 21 enter the first liquid outlet pipe 221 and the first inlet pipe 222 after being filtered by the ceramic filter material and the metal filter material, and the enzyme preparations in the first inlet pipe 222 are synchronously introduced into the first liquid outlet pipe 221;

[0028] When secondary filtration is performed, all valves except the first inlet pipe 222 can be loosened, at this time the enzyme preparations in the filter cartridge body 212 located on the left side enter the second liquid outlet pipe 225 under the action of gravity, the enzyme preparations in the filter cartridge body 212 located on the right side enter the second inlet pipe 223 under the action of gravity, and then enter the second liquid outlet pipe 225 through the third inlet pipe 224, and the enzyme preparations remaining in the first liquid outlet pipe 221 also enter the second liquid outlet pipe 225 through the connecting pipe 226, nano-fiber filter material is internally provided at the front and back ends of each valve group, the nano-fiber filter material has high porosity and high filtration efficiency, can reduce the shear damage of enzymes during filtration, and the multi-section setting mode can well achieve the effect of secondary filtration, when the filter material is replaced, the filter material at the corresponding position can be taken out only by disassembling the valve at the corresponding position, and the multi-section design is also convenient for overall cleaning and maintenance.

[0029] It should be understood by those of ordinary skill in the art that the above discussion of any of the embodiments is merely exemplary and is not intended to suggest that the scope of the present application includes only these examples; the above embodiments or technical features among different embodiments can also be combined, the steps can be implemented in any order, and there are many other changes of different aspects of the present application as above, which are not provided in detail for the sake of brevity.

[0030] The present application is intended to cover all such alternatives, modifications, and variations as fall within the broad scope of the appended claims. Accordingly, any and all such alternatives, modifications and variations should be included within the scope of the present application.

Claims

1. An improved enzyme preparation sterile filtration apparatus, characterized by: Including fixed frame (1), fixedly connected with filter structure (2) inside fixed frame (1), filter structure (2) includes single group filter cartridge (21), single group filter cartridge (21) is equipped with two groups, and two groups single group filter cartridge (21) bottom fixedly connected with liquid outlet pipeline (22).

2. An improved apparatus for sterile filtration of enzyme preparation as claimed in claim 1 wherein: The fixed frame (1) includes a frame body (11), the frame body (11) is fixedly connected with a climbing ladder (12) inside the front side, and the frame body (11) is fixedly connected with a fixed table top (13) inside the top end.

3. An improved apparatus for sterile filtration of enzyme preparation as claimed in claim 2 wherein: The single group filter cartridge (21) includes a filter cartridge cover (211), the filter cartridge cover (211) is fixedly connected with a filter cartridge body (212) at the bottom end by means of bolts, the filter cartridge body (212) is fixedly connected with a connecting piece (213) on the outer wall, the connecting piece (213) is provided with four groups and is fixedly connected with the filter cartridge body (212) outer wall four around, the single group filter cartridge (21) is fixed with the fixed table top (13) by four connecting pieces (213).

4. An improved apparatus for sterile filtration of enzyme preparation as claimed in claim 3 wherein: The liquid outlet pipeline (22) includes a first liquid outlet pipe (221), one end of the first liquid outlet pipe (221) is fixedly connected with the outside of the single group filter cartridge (21) on the left side, the first liquid outlet pipe (221) is fixedly connected with a first inlet pipe (222) and a second inlet pipe (223) on the outer wall of one end, one end of the first inlet pipe (222) is fixedly connected with the outside of the single group filter cartridge (21) on the right side, one end of the second inlet pipe (223) is fixedly connected with the bottom end of the single group filter cartridge (21) on the right side, the second inlet pipe (223) is fixedly connected with a third inlet pipe (224) on the outer wall, one end of the third inlet pipe (224) is fixedly connected with the second liquid outlet pipe (225), one end of the second liquid outlet pipe (225) is fixedly connected with the bottom end of the single group filter cartridge (21) on the left side, and the second liquid outlet pipe (225) is fixedly connected with the first liquid outlet pipe (221) between the connecting pipe (226).

5. An improved apparatus for sterile filtration of enzyme preparation as claimed in claim 4 wherein: Valves are installed inside the first inlet pipe (222), the second inlet pipe (223), the third inlet pipe (224), the second liquid outlet pipe (225) and the connecting pipe (226).

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