Exosome nucleic acid collection container

Abstract

The utility model discloses an exosome nucleic acid collection container, which relates to the technical field of nucleic acid collection and comprises a collection container main body, a movable cover plate is movably inserted into the top of the collection container main body, an inner supporting plate is fixedly mounted on the inner wall of the collection container main body, and a collection test tube is movably inserted into the top of the inner supporting plate. An automatic cut-off mechanism is arranged on the back of the collection container body, and a low-temperature storage mechanism is arranged on the front of the collection container body. Through the design of the electric push rod, the electric push rod is controlled to stretch, the sliding block can be driven to slide towards the front side on the outer wall of the limiting rod, then the cutting-off cutter body is pushed to move forwards through transmission of the connecting block, and the function of automatically cutting off cotton swabs can be achieved by means of matching of the cutting edge at the front end of the cutting-off cutter body and the inner wall of the cutting-off frame; the cut cotton swab falls into the inner cavity of the collecting test tube under the action of gravity, so that the labor intensity of medical personnel can be reduced, and the efficiency of exosome nucleic acid collecting work is improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to nucleic acid collection technical field, concretely relates to exosome nucleic acid collection container. BACKGROUND

[0002] Exosome nucleic acid is the genetic material carried in the exosome, mainly including RNA and DNA fragments. Exosome is a nanometer vesicle secreted by cells, widely exists in body fluids such as blood, saliva, urine, etc., and serves as a carrier for information transmission between cells. Exosome nucleic acid collection container is a device for collecting, preserving and transporting exosome nucleic acid samples, which needs to meet the requirements of protecting the integrity of exosomes and preventing nucleic acid degradation.

[0003] The existing collection container does not have the function of automatically breaking the cotton swab. In the process of exosome nucleic acid collection, in order to improve efficiency, multiple collected cotton swabs are added to the same test tube. During the collection process, the medical staff needs to manually break the cotton swab in turn, which leads to the problem of high labor intensity of the medical staff. UTILITY MODEL CONTENT

[0004] The utility model aims at providing exosome nucleic acid collection container to solve the problems in the above background technology.

[0005] To solve the above technical problems, the utility model adopts the technical scheme of:

[0006] The exosome nucleic acid collection container comprises a collection container main body, a movable cover plate movably connected to the top of the collection container main body, an inner support plate fixedly installed on the inner wall of the collection container main body, a collection test tube movably connected to the top of the inner support plate, an automatic cutting mechanism arranged on the back of the collection container main body, and a low-temperature preservation mechanism arranged on the front of the collection container main body.

[0007] The automatic cutting mechanism comprises a guide rail rod fixedly installed on the back of the collection container main body, a sliding seat detachably connected to the outer wall of the guide rail rod, a positioning bolt threadedly connected to the back of the sliding seat, a screw end of the positioning bolt movably connected to the outer wall of the guide rail rod, a support fixedly installed on the back of the sliding seat, a movable battery compartment fixedly installed on the bottom of the support, a cutting frame fixedly installed on the end of the front of the support, and a control button fixedly installed on the side of the cutting frame.

[0008] Preferably, a limiting rod is fixedly installed on the inner wall of the cutting frame, an electric push rod is fixedly installed on the back of the cutting frame, a sliding block is slidably connected to the outer wall of the limiting rod, and the telescopic end of the electric push rod extends into the inner cavity of the cutting frame and is fixedly connected to the back of the sliding block.

[0009] Preferably, the front surface of the sliding block is fixedly provided with a connecting block, the front surface of the connecting block is provided with a groove, the inner cavity of the groove is movably inserted with a cutting knife body, and the top of the connecting block is threadedly connected with a bolt, and the threaded end of the bolt is movably connected with the top of the cutting knife body.

[0010] Preferably, the low-temperature preservation mechanism comprises a hollow plate fixedly installed on the front surface of the collection container body, and a pipeline fan fixedly connected with the front surface of the hollow plate.

[0011] Preferably, the front surface of the hollow plate is fixedly connected with a second circulating pipe, and the end, away from the hollow plate, of the second circulating pipe is fixedly connected with the front surface of the collection container body.

[0012] Preferably, the front surface of the hollow plate is provided with a square groove between the pipeline fan and the second circulating pipe, an aluminum alloy plate is fixedly installed on the inner wall of the square groove, and a semiconductor refrigerator is fixedly installed on the front surface of the aluminum alloy plate.

[0013] Thanks to the above technical scheme, the present application has the following technical progress compared with the prior art:

[0014] The utility model provides exosome nucleic acid collection container, in order to solve the problem that manual folding processing is carried out to cotton swab in prior art in turn, and the labor intensity of medical staff is big. Through the design of electric push rod, control its extension work can drive the sliding block to slide to the front surface on the outer wall of the limiting rod, and then the cutting knife body is driven to displace forward through the transmission of the connecting block, and the blade at the front end of the cutting knife body cooperates with the inner wall of the cutting frame, so that the function of automatically cutting the cotton swab can be realized, and the cotton swab after cutting falls into the inner cavity of the collection test tube under the action of gravity, so that the labor intensity of medical staff can be reduced, and the efficiency of exosome nucleic acid collection work can be improved. BRIEF DESCRIPTION OF DRAWINGS

[0015] Figure 1 It is the whole structure schematic view of the utility model;

[0016] Figure 2 It is the internal structure schematic view of the collection container body of the utility model;

[0017] Figure 3 It is the structure schematic view of the automatic cutting mechanism of the utility model;

[0018] Figure 4 It is the structure schematic view of the connecting block and the cutting knife body of the utility model;

[0019] Figure 5The utility model discloses low temperature preservation mechanism's structure schematic drawing.

[0020] Figure 6 The utility model discloses hollow plate's whole decomposition structure schematic drawing.

[0021] In the drawing: 1, the collection container main part; 11, movable cover plate; 12, inner bracing plate; 13, collection test tube; 2, automatic cutting mechanism; 21, guide rail rod; 22, sliding seat; 23, positioning bolt; 24, support; 25, movable battery compartment; 26, cutting frame; 27, limiting rod; 28, electric push rod; 281, sliding block; 282, connecting block; 283, recess; 284, cutting knife body; 285, bolt; 29, control button; 3, low temperature preservation mechanism; 31, hollow plate; 311, square groove; 312, aluminum alloy plate; 313, semiconductor refrigerator; 32, pipeline fan; 33, no. One circulating pipe; 34, no. Two circulating pipes. Specific embodiments

[0022] The utility model makes further detailed explanation in combination with the embodiment:

[0023] As Figures 1-6 The utility model discloses exosome nucleic acid collection container, including collection container main part 1, movable cover plate 11 is inserted to the top of collection container main part 1, the inner wall on collection container main part 1 is fixedly installed with inner bracing plate 12, the top movable cover plate 11 is inserted to the inner bracing plate 12, and collection test tube 13 is inserted to the top of movable cover plate 11, and the back of collection container main part 1 is provided with automatic cutting mechanism 2, and the front of collection container main part 1 is provided with low temperature preservation mechanism 3, and automatic cutting mechanism 2 includes guide rail rod 21, and guide rail rod 21 is fixedly installed on the back of collection container main part 1, and the outer wall on guide rail rod 21 is detachably connected with sliding seat 22, and the back of sliding seat 22 is screw connected with positioning bolt 23, and the threaded end of positioning bolt 23 is movably connected with the outer wall of guide rail rod 21, and the back of sliding seat 22 is fixedly installed with support 24, and the bottom of support 24 is fixedly installed with movable battery compartment 25, and the end of the front of support 24 is fixedly installed with cutting frame 26, and the side of cutting frame 26 is fixedly installed with control button 29, and positioning bolt 23 is loosened, and then sliding seat 22 can slide on the outer wall of guide rail rod 21, and then cutting knife body 284 can be adjusted to the top of different collection test tubes 13, and after adjusting in place, positioning bolt 23 is tightened, and the positioning of cutting knife body 284 is completed, and after loosening positioning bolt 23, sliding seat 22 can be detached from guide rail rod 21, and then can be loaded to the guide rail rod 21 of another collection container main part 1, so that electric push rod 28 can be used on different collection container main part 1, reduce production cost, and the inside of movable battery compartment 25 contains battery, and the battery is used to power supply for electric push rod 28.

[0024] Further, as Figures 1-4As shown, the inner wall of the cutting frame 26 is fixedly provided with a limiting rod 27, the back of the cutting frame 26 is fixedly provided with an electric push rod 28, the outer wall of the limiting rod 27 is slidably connected with a sliding block 281, the telescopic end of the electric push rod 28 extends into the inner cavity of the cutting frame 26 and is fixedly connected with the back of the sliding block 281, the front of the sliding block 281 is fixedly provided with a connecting block 282, the front of the connecting block 282 is provided with a groove 283, the inner cavity of the groove 283 is movably inserted with a cutting knife body 284, the top of the connecting block 282 is threadedly connected with a bolt 285, the threaded end of the bolt 285 is movably connected with the top of the cutting knife body 284, the control button 29 is of a prior structure, which is used to control the telescopic work of the electric push rod 28, after the exosome nucleic acid is collected by using a cotton swab, the cotton swab is moved into the inner cavity of the cutting frame 26 in front of the cutting knife body 284, then the telescopic work of the electric push rod 28 is controlled from the control button 29, the cutting knife body 284 can be moved forward and then reset, in the process of moving forward of the cutting knife body 284, the cutting knife body 284 is assisted by the blade at the front end to cooperate with the inner wall of the cutting frame 26, so as to realize the function of automatically cutting the cotton swab, the cut cotton swab falls into the inner cavity of the collection test tube 13 under the action of gravity, which replaces the manual operation and reduces the consumption of manpower, the bolt 285 is loosened, then the cutting knife body 284 can be pulled out from the inner cavity of the groove 283, which is convenient for the user to replace the cutting knife body 284, the bolt 285 is tightened, which can fix the cutting knife body 284.

[0025] Further, as Figure 5 、 Figure 6As shown, the low-temperature storage mechanism 3 includes a hollow plate 31 fixedly installed on the front face of the collection container body 1, the front face of the hollow plate 31 is fixedly connected with a pipeline fan 32, one end of the pipeline fan 32 away from the hollow plate 31 is fixedly connected with a first circulating pipe 33, one end of the first circulating pipe 33 away from the pipeline fan 32 is fixedly connected on the front face of the collection container body 1, the front face of the hollow plate 31 is fixedly connected with a second circulating pipe 34, one end of the second circulating pipe 34 away from the hollow plate 31 is fixedly connected on the front face of the collection container body 1, the front face of the hollow plate 31 is provided with a square groove 311 between the pipeline fan 32 and the second circulating pipe 34, an aluminum alloy plate 312 is fixedly installed on the inner wall of the square groove 311, the front face of the aluminum alloy plate 312 is fixedly installed with a semiconductor refrigerator 313, after the exosome nucleic acid collection is completed, the movable cover plate 11 is closed, if the environmental temperature for waiting for detection is high, the pipeline fan 32 is controlled to work, the air inside the collection container body 1 can be absorbed from the end of the first circulating pipe 33, and then transported into the inner cavity of the hollow plate 31, the air is then backflowed to the collection container body 1 through the second circulating pipe 34, the function of driving the air inside the collection container body 1 to circulate through the inner cavity of the hollow plate 31 is realized, the semiconductor refrigerator 313 is controlled to work at the same time, the air flowing in the inner cavity of the hollow plate 31 is cooled, and then the temperature in the inner cavity of the collection container body 1 is reduced, so that the problem that the sample is prone to deterioration in the process of waiting for detection is avoided, the bottom of the collection container body 1 is provided with a power supply, the power supply is used for supplying power for the pipeline fan 32 and the semiconductor refrigerator 313, through the design of the square groove 311 and the aluminum alloy plate 312, the heat exchange rate of the cold end of the semiconductor refrigerator 313 and the air inside the hollow plate 31 can be improved.

[0026] The working principle of the exosome nucleic acid collection container will be described in detail below.

[0027] As Figures 1-6As shown, in use, the movable cover plate 11 is pulled out from the top of the collection container body 1, and the cover at the top of the collection test tube 13 is opened, the exosome nucleic acid is collected by using a cotton swab, and then the cotton swab is moved into the inner cavity of the cutting frame 26 at the front end of the cutting knife body 284, and then the control button 29 controls the telescopic work of the electric push rod 28, the cutting knife body 284 can be moved forward and then reset, in the process of moving forward of the cutting knife body 284, the cutting knife body 284 at the front end cooperates with the inner wall of the cutting frame 26 to realize the function of automatically cutting the cotton swab, in the process, the positioning bolt 23 is loosened, and then the sliding seat 22 can slide on the outer wall of the guide rail 21, so that the cutting knife body 284 can be adjusted to the top of different collection test tubes 13, after adjustment, the positioning bolt 23 is tightened to complete the positioning of the cutting knife body 284 as a whole, after sampling, the cover on the collection test tube 13 and the movable cover plate 11 are reset, if the environment temperature for detection is high, the pipeline fan 32 is controlled to work to realize the function of driving the air in the collection container body 1 to circulate through the inner cavity of the hollow plate 31, and the semiconductor refrigerator 313 is controlled to work to cool the air flowing in the hollow plate 31, so as to reduce the temperature in the inner cavity of the collection container body 1, and realize the function of low-temperature storage of the sample.

[0028] It should be noted that in the description of the present disclosure, it is necessary to explain that unless otherwise explicitly specified and limited, the terms "mounting", "connecting", "connecting" should be understood broadly, for example, it can be fixedly connected, or it can be detachably connected, or integrally connected, it can be mechanically connected, it can be directly connected, or indirectly connected through an intermediate medium, it can be the internal communication of two elements or the interaction relationship between two elements. For ordinary skilled in the art, the specific meaning of the above terms in the present disclosure can be understood according to the specific circumstances.

[0029] The above has made a detailed description of the present application, but some modifications or improvements can be made on the basis of the present application, which is obvious to those skilled in the art. Therefore, the modifications or improvements without departing from the spirit of the present application are within the protection scope of the present application.

Claims

1. An exosome nucleic acid collection container, characterized by: The application relates to a collection container, which comprises a collection container body, a movable cover plate movably inserted on the top of the collection container body, an inner support plate fixedly installed on the inner wall of the collection container body, a collection test tube movably inserted on the top of the inner support plate, an automatic cutting mechanism arranged on the back of the collection container body, and a low-temperature storage mechanism arranged on the front of the collection container body. The automatic cutting mechanism comprises a guide rail rod fixedly installed on the back of the collection container body, a sliding seat detachably connected to the outer wall of the guide rail rod, a positioning bolt screwedly connected to the back of the sliding seat, a threaded end of the positioning bolt movably connected with the outer wall of the guide rail rod, a support fixedly installed on the back of the sliding seat, a movable battery compartment fixedly installed on the bottom of the support, a cutting frame fixedly installed on the end of the front of the support, and a control button fixedly installed on the side of the cutting frame.

2. The exosome nucleic acid collection vessel of claim 1, wherein: A limiting rod is fixedly installed on the inner wall of the cutting frame, an electric push rod is fixedly installed on the back of the cutting frame, a sliding block is slidably connected to the outer wall of the limiting rod, and the telescopic end of the electric push rod extends into the inner cavity of the cutting frame and is fixedly connected with the back of the sliding block.

3. The exosome nucleic acid collection vessel of claim 2, wherein: A connecting block is fixedly installed on the front of the sliding block, a groove is formed in the front of the connecting block, a cutting knife body is movably inserted into the inner cavity of the groove, a bolt is screwedly connected with the top of the connecting block, and the threaded end of the bolt is movably connected with the top of the cutting knife body.

4. The exosome nucleic acid collection container of claim 1, wherein: The low-temperature storage mechanism comprises a hollow plate fixedly installed on the front of the collection container body, a pipeline fan fixedly connected with the front of the hollow plate, a first circulating pipe fixedly connected with the end of the pipeline fan away from the hollow plate, and the first circulating pipe is fixedly connected with the front of the collection container body.

5. The exosome nucleic acid collection vessel of claim 4, wherein: A second circulating pipe is fixedly connected with the front of the hollow plate, and the second circulating pipe is fixedly connected with the front of the collection container body away from the hollow plate.

6. The exosome nucleic acid collection vessel of claim 5, wherein: A square groove is formed in the front of the hollow plate between the pipeline fan and the second circulating pipe, an aluminum alloy plate is fixedly installed on the inner wall of the square groove, and a semiconductor refrigerator is fixedly installed on the front of the aluminum alloy plate.

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