Resin adsorption device

Abstract

The utility model relates to a resin adsorption device, and belongs to the technical field of experimental apparatuses. The adsorption device comprises a chromatography through pipe and a filtering assembly, a plurality of conical circular truncated cones with gradually decreased diameters are arranged at one end of the chromatography through pipe in the length direction, the filtering assembly comprises an upper sieve plate and a lower sieve plate, the upper sieve plate and the lower sieve plate are arranged at the junction corners of the conical circular truncated cones respectively, and a storage space is formed between the upper sieve plate and the lower sieve plate; the material storage space can be formed by putting the lower sieve plate and the upper sieve plate into the chromatography through pipe, compared with the structure formed by connecting two sieve plates through a supporting strip in the prior art, the structure is simpler, and use is more convenient and faster; the two ends of the conical circular truncated cone can form clamping positions of the upper sieve plate and the lower sieve plate, the fixing and positioning effects are achieved, no additional positioning structure is needed, and the structure is simple and practical.

Description

Technical Field

[0001] This application relates to the field of experimental instruments and apparatus technology, and in particular to a resin adsorption device. Background Technology

[0002] Macroporous resins, also known as fully porous resins, are mainly made from raw materials such as styrene and divinylbenzene. They have stable physicochemical properties, are insoluble in acids, alkalis and organic solvents, have good selectivity for organic matter, and are not affected by the presence of inorganic salts, strong ions and low molecular weight compounds. Their adsorption principle is to selectively adsorb organic substances from the solution through physical adsorption, thereby achieving the purpose of separation and purification.

[0003] Current macroporous resin adsorption equipment is generally tubular. Tubular macroporous resin adsorption equipment is generally equipped with a feed port and a discharge port, and a storage space is formed by a sieve plate. However, in the current market, the storage space structure is relatively complex, resulting in technical defects such as high equipment cost or inconvenience of use.

[0004] A domestic utility model patent, application number CN202320035157.2, discloses an adsorption device for macroporous resin, comprising an adsorption device body, an inlet pipe provided at the middle of one end of the adsorption device body, a sealing cover plate installed at the other end of the adsorption device body, an outlet pipe provided at the middle of one end of the sealing cover plate, a small circular filter plate installed inside the outlet pipe, and a feed pipe provided on one side of the outer wall of the adsorption device body near the inlet pipe. By using a combination of small circular filter plates, a sealing cover, an annular baffle, support bars, and a large circular filter plate, a storage space can be formed inside the equipment. The storage space is formed by welding an annular baffle to the other end of the sealing cover. The diameter of the annular baffle is the same as the inner diameter of the adsorption equipment body. Support bars are symmetrically arranged on the inner wall of the annular baffle, and a large circular filter plate is welded to one end of the support bar. The diameter of the large circular filter plate is the same as the inner diameter of the adsorption equipment body. The arrangement of the small and large circular filter plates can prevent the macroporous resin from detaching from the equipment and form a storage space. This equipment not only requires the connection of the small and large circular filter plates through the support bar structure, but also requires a side feed port between the two circular screen plates to add resin to the storage space because the two circular screen plates are fixedly connected to each other. The structure is relatively complex and inconvenient to operate.

[0005] Therefore, in view of the above problems, this utility model proposes a new type of macroporous resin adsorption device. The storage space for macroporous resin is constructed through a simple structure. This utility model can not only reduce the production cost of the equipment, but also facilitate the operation of the operator. It can complete the feeding of macroporous resin without the need for a separate macroporous resin inlet. Utility Model Content

[0006] To overcome the problems existing in related technologies, the purpose of this application is to provide a resin adsorption device. The adsorption device includes a chromatography tube and a filter assembly. One end of the chromatography tube is provided with several conical truncated cones with decreasing diameters along its length. The filter assembly includes an upper sieve plate and a lower sieve plate, which are respectively placed at the junction of the conical truncated cones. A storage space is formed between the upper sieve plate and the lower sieve plate. In the process of using this invention, the lower sieve plate is placed first, then the resin is put into the chromatography tube, and then the upper sieve plate is placed, thereby forming a resin adsorption device with resin material inside. This resin adsorption device has a simple structure and is easy to use.

[0007] One of the objectives of this invention is to provide a resin adsorption device.

[0008] The adsorption device includes a chromatography tube and a filtration assembly. One end of the chromatography tube has several conical truncated cones with decreasing diameters along its length. The filtration assembly includes an upper sieve plate and a lower sieve plate, which are respectively placed at the junction of the conical truncated cones. A storage space is formed between the upper sieve plate and the lower sieve plate.

[0009] In a preferred embodiment of this application, the resin adsorption device further includes an inner filter tube that can be placed inside the chromatography tube. The bottom of the inner filter tube is provided with a filter sieve plate, and the upper end of the inner filter tube is provided with a tube beam for easy gripping.

[0010] In a preferred embodiment of this application, a gap is provided between the outer wall of the filter inner tube and the inner wall of the chromatography tube.

[0011] In a preferred embodiment of this application, the tube beam is annular, and the lower end face of the tube beam is provided with a support column that supports the end face of the chromatography tube.

[0012] In a preferred embodiment of this application, the resin adsorption device further includes a fixing base, which includes an upper cover plate and a base, and the upper cover plate is provided with a plurality of chromatography tube placement holes.

[0013] In a preferred embodiment of this application, a waste liquid tank is provided below the plurality of chromatography tube placement holes.

[0014] In a preferred embodiment of this application, a reagent tube placement hole is provided next to the plurality of chromatography tube placement holes.

[0015] In a preferred embodiment of this application, a limiting groove for limiting the reagent tube cap is provided between the plurality of reagent tube placement holes and the edge of the upper cover plate. The width of the limiting groove is consistent with the connecting part of the reagent tube, and the connecting part is the part that connects the reagent tube and the cap.

[0016] In a preferred embodiment of this application, the distance between the upper cover and the base is greater than the height of the reagent tube.

[0017] In a preferred embodiment of this application, the size of the upper sieve plate is larger than that of the lower sieve plate, the mesh size of the upper sieve plate is 15-30 mesh, the mesh size of the lower sieve plate is 15-30 mesh, and the mesh size of the filter sieve plate is 20-50 mesh.

[0018] The beneficial effects of the technical solution provided in this application are as follows:

[0019] The adsorption device of this application includes a chromatography tube and a filter assembly. One end of the chromatography tube has several conical truncated cones with decreasing diameters along its length. The filter assembly includes an upper sieve plate and a lower sieve plate, which are respectively placed at the junction of the conical truncated cones. The space between the upper sieve plate and the lower sieve plate forms a storage space. In the process of using this resin adsorption device, the lower sieve plate is placed first, then the resin is put into the chromatography tube, and then the upper sieve plate is placed, thus forming a resin adsorption device with resin material inside. The storage space is formed by placing the lower sieve plate and the upper sieve plate into the chromatography tube respectively. Compared with the existing technology, the structure composed of two sieve plates connected by a support strip is simpler and more convenient to use. In addition, the chromatography tube of this application has several conical truncated cones with decreasing diameters. The two ends of the conical truncated cones can form the locking positions of the upper sieve plate and the lower sieve plate, which play a fixed positioning role. There is no need for a separate positioning structure. The structure is simple and practical. Attached Figure Description

[0020] Figure 1 This is a schematic diagram of the resin adsorption device structure shown in the embodiments of this application;

[0021] Figure 2 This is a schematic diagram of the resin adsorption device (including a fixing base) shown in the embodiments of this application;

[0022] Figure 3 This is another structural schematic diagram of the resin adsorption device (including the fixing base) shown in the embodiments of this application;

[0023] Figure 4 This is a schematic diagram of the structure of the upper cover plate shown in an embodiment of this application;

[0024] Figure 5 This is a schematic diagram of the base structure shown in an embodiment of this application;

[0025] Figure 6 This is a schematic diagram of the structure of the filter inner tube shown in the embodiments of this application;

[0026] Figure 7 This is a cross-sectional view of the filter inner tube shown in an embodiment of this application;

[0027] Figure 8 This is a schematic cross-sectional view of the chromatography tube shown in an embodiment of this application;

[0028] Figure 9 This is a cross-sectional structural schematic diagram of the resin adsorption device shown in the embodiments of this application.

[0029] Figure label:

[0030] 1. Chromatography tube; 11. Inlet; 12. Outlet; 13. Conical frustum; 2. Filter assembly; 21. Upper sieve plate; 22. Lower sieve plate; 3. Inner filter tube; 31. Tube beam; 32. Support column; 34. Filter sieve plate; 4. Fixing base; 41. Upper cover plate; 42. Base; 43. Chromatography tube placement hole; 44. Waste liquid tank; 45. Reagent tube placement hole; 46. Limiting groove; 5. Reagent tube; 6. Air circulation channel. Detailed Implementation

[0031] Preferred embodiments of the present invention will now be described in more detail with reference to the accompanying drawings. While preferred embodiments of the present invention are shown in the drawings, it should be understood that the present invention may be implemented in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided so that the present invention will be thorough and complete, and will fully convey the scope of the present invention to those skilled in the art.

[0032] The terminology used in this invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The singular forms “a,” “the,” and “the” used in this invention and the appended claims are also intended to include the plural forms unless the context clearly indicates otherwise. It should also be understood that the term “and / or” as used herein refers to and includes any or all possible combinations of one or more of the associated listed items.

[0033] It should be understood that although the terms "first," "second," "third," etc., may be used in this invention to describe various information, this information should not be limited to these terms. These terms are only used to distinguish information of the same type from one another. For example, without departing from the scope of this invention, first information may also be referred to as second information, and similarly, second information may also be referred to as first information. Thus, features defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this invention, "a plurality of" means two or more, unless otherwise explicitly specified.

[0034] Example 1

[0035] Current macroporous resin adsorption equipment is generally tubular, with an inlet and outlet, and a storage space formed by a sieve plate. However, in current market applications, the complex structure of the storage space leads to high equipment costs or inconvenient operation. To address these issues, this application proposes a novel macroporous resin adsorption device with a simpler structure for storing macroporous resin. This invention not only reduces production costs but also facilitates operation, eliminating the need for a separate macroporous resin inlet for feeding. The following detailed description, in conjunction with the accompanying drawings, further illustrates this application.

[0036] See Figures 1 to 9 .

[0037] The resin adsorption device in this application embodiment does not limit the type of resin used. Exemplarily, this application embodiment uses macroporous adsorption resin, also known as fully porous resin or polymer adsorbent. It is a type of high-molecular-weight adsorbent without ion exchange groups and possessing a macroporous network structure. It belongs to porous cross-linked polymers and has the function of separating and enriching organic matter. It is generally white, milky white, or yellow granules; some newer resins are yellow, brownish-yellow to reddish-brown, with a particle size typically of 20–60 mesh. It is physically and chemically stable, insoluble in water, acids, alkalis, and hydrophilic organic solvents, and does not dissolve upon heating. It can be used below 150°C. Macroporous resin has a good network structure and a large specific surface area, combining adsorption and molecular sieve separation principles. Its adsorption is due to van der Waals forces or the formation of hydrogen bonds. Resins with different polarities and pore sizes exhibit different selectivity for different types of compounds, thereby achieving the purpose of separation and purification. The adsorption of resins is a physicochemical process; adsorbed substances are easily eluted from the resin, and the resin itself is also easily regenerated. Therefore, macroporous adsorption resins possess advantages such as high selectivity, high mechanical strength, convenient regeneration, fast adsorption rate, and are unaffected by the presence of inorganic salts, strong ions, and low-molecular-weight compounds. Macroporous adsorption resins have been widely used in the extraction and separation of natural products in recent years, and this application can be used for the adsorption and washing of macroporous adsorption resins.

[0038] The adsorption device of this application includes a chromatography tube 1 and a filter assembly 2. The chromatography tube 1 includes an inlet 11 and an outlet 12. Macroporous adsorption resin and the sample to be separated and purified can be added through the inlet 11, and the remaining sample liquid not adsorbed by the macroporous resin can flow out through the outlet 12. In this embodiment, the outlet 12 of the chromatography tube 1 is provided with a plurality of conical frustums 13 with decreasing diameters along its length, that is, a plurality of conical frustums 13 with decreasing diameters are connected end to end to end. This embodiment does not limit the number of conical frustums 13 and can be set according to the actual situation. In this embodiment, three conical frustums 13 are provided. For example, in this embodiment, a cylindrical step can also be provided at the end of the conical frustum 13 with a larger diameter to increase the storage space formed by the filter assembly 2.

[0039] The filter assembly 2 in this embodiment includes an upper screen plate 21 and a lower screen plate 22. For example, the size of the upper screen plate 21 is larger than the size of the lower screen plate 22. The upper screen plate 21 and the lower screen plate 22 are respectively placed at the junction corner of the conical frustum 13, and a storage space is formed between the upper screen plate 21 and the lower screen plate 22.

[0040] Furthermore, when it is necessary to extract and separate natural products, such as target proteins in urine samples, this resin adsorption device is used. The macroporous resin required for the adsorbed protein marker is selected, and the appropriate number of pores for the upper sieve plate 21 and lower sieve plate 22 is chosen based on the macroporous resin. The lower sieve plate 22 is placed into the chromatography tube 1, where it will be positioned at the corner junction of the conical frustum 13. An appropriate amount of macroporous resin is added, and the upper sieve plate 21 is then added above the macroporous resin at the corner junction of the conical frustum 13, thus forming the macroporous resin adsorption device. The urine sample to be extracted and separated is added to the chromatography tube 1. The macroporous resin in the chromatography tube 1 will adsorb the target protein in the urine sample, and the waste liquid flows out through the outlet 12. After a certain period of adsorption, the resin adsorption device completes the adsorption of the urine sample. The upper sieve plate 21 is then removed, and the macroporous resin is washed and recovered using a washing solution, thereby separating the target protein.

[0041] The beneficial effects of the embodiments of this application are as follows: In the process of using this resin adsorption device, the lower sieve plate is placed first, then the resin is put into the chromatography tube, and then the upper sieve plate is placed, thereby forming a resin adsorption device with resin material inside. The storage space can be formed by placing the lower sieve plate and the upper sieve plate into the chromatography tube respectively. Compared with the existing technology, the structure composed of two sieve plates connected by support strips is simpler and more convenient to use. In addition, the chromatography tube of this application has several conical frustums with decreasing diameters. The two ends of the conical frustums can form the snap-fit ​​positions of the upper sieve plate and the lower sieve plate, which play a fixed positioning role. There is no need for a separate positioning structure. The structure is simple and practical.

[0042] Example 2

[0043] The resin adsorption device of the above embodiment 1 can extract and separate the target product in the sample. However, in actual application, if there are many impurities in the sample, the impurities will block the upper sieve plate or block the upper layer of macroporous resin, causing the sample to be unable to flow downwards and resulting in the termination of adsorption. Therefore, the embodiments of this application have improved the above problem.

[0044] See Figures 1 to 9 .

[0045] The resin adsorption device of this application embodiment includes the structural features of Embodiment 1, including a chromatography tube 1 and a filter assembly 2. The chromatography tube 1 includes an inlet 11 and an outlet 12. The outlet 12 is provided with a plurality of conical frustums 13 with decreasing diameters along its length. The filter assembly 2 includes an upper sieve plate 21 and a lower sieve plate 22. The upper sieve plate 21 and the lower sieve plate 22 are respectively placed at the junction corners of the conical frustums 13, and a storage space is formed between the upper sieve plate 21 and the lower sieve plate 22.

[0046] Furthermore, the resin adsorption device also includes a filter inner tube 3 that can be placed inside the chromatography tube 1. The bottom of the filter inner tube 3 is provided with a filter sieve plate 34, and the upper end of the filter inner tube 3 is provided with a tube beam part 31 that is easy to hold.

[0047] In this embodiment of the application, the filter inner tube 3 is placed inside the chromatography tube 1. The filter inner tube 3 is an open filter inner tube 3 at both ends. The bottom of the filter inner tube 3 is provided with a filter sieve plate 34, which can filter out impurities in the sample and prevent the sample adsorption process from being blocked and stopping the adsorption.

[0048] Furthermore, a gap is provided between the outer wall of the inner filter tube 3 and the inner wall of the chromatography tube 1. This gap forms an airflow channel. Without this airflow channel, especially for liquid samples, during downward flow, the air in the filter sieve plate 34 to the upper sieve plate 21 within the chromatography tube 1 is forced out, creating a vacuum space where the air pressure is lower than atmospheric pressure, preventing the sample liquid from flowing downwards. This embodiment of the application solves the problem of the liquid being unable to flow downwards by providing an airflow channel, maintaining pressure balance between the space between the filter sieve plate 34 and the upper sieve plate 21 and the outside air.

[0049] Furthermore, the upper end of the filter inner tube 3 is provided with a tube beam 31 for easy gripping. The tube beam 31 is annular, and the lower end face of the tube beam 31 is provided with a support column 32 that supports the end face of the chromatography tube 1. The support column 32 can prevent the tube beam 31 from sticking to the upper end of the chromatography tube 1 and sealing it, so as to ensure the flow of air between the air circulation section and the outside air and the pressure balance.

[0050] The beneficial effects of the embodiments of this application are as follows:

[0051] This application embodiment solves the problem of liquid not being able to flow downwards by setting up an air circulation channel to maintain the pressure balance between the space between the filter screen plate and the upper screen plate and the outside air.

[0052] The filter inner tube is placed inside the chromatography tube. The filter inner tube is open at both ends and has a filter sieve plate at the bottom, which can filter out impurities in the sample and prevent the sample adsorption process from becoming blocked and stopping adsorption.

[0053] The support column can prevent the tube beam from sticking to the upper end of the chromatography tube and covering it, thus ensuring the air circulation section can communicate with the outside air and maintain pressure balance.

[0054] Example 3

[0055] This application provides a further inventive design for a resin adsorption device.

[0056] See Figures 1 to 9 .

[0057] The resin adsorption device of this application embodiment includes the structural features of Embodiment 1 or Embodiment 2. The adsorption device includes a chromatography tube 1 and a filter assembly 2. The chromatography tube 1 includes an inlet 11 and an outlet 12. The outlet 12 is provided with a plurality of conical frustums 13 with decreasing diameters along its length. The filter assembly 2 includes an upper sieve plate 21 and a lower sieve plate 22. The upper sieve plate 21 and the lower sieve plate 22 are respectively placed at the junction corners of the conical frustums 13. A storage space is formed between the upper sieve plate 21 and the lower sieve plate 22.

[0058] Furthermore, the resin adsorption device in this embodiment also includes a fixing base 4, which includes an upper cover plate 41 and a base 42. The upper cover plate 41 is provided with a plurality of chromatography tube placement holes 43. The fixing base 4 is provided for the fixed installation of the resin adsorption device, making it convenient for operators to use the resin adsorption device to adsorb target proteins.

[0059] Furthermore, a waste liquid tank 44 is provided below several chromatography tube placement holes 43. The waste liquid tank 44 is used to hold the waste liquid that has flowed through the resin adsorption device.

[0060] Furthermore, in this embodiment of the resin adsorption device, a reagent tube placement hole 45 is also provided next to several attached tube placement holes. The reagent tube placement holes 45 are distributed on the edge of the upper cover plate 41. The reagent tube placement holes 45 are used to place reagent tubes. Specifically, after placing the reagent tube into the reagent tube placement hole 45, the resin adsorption device that has completed the adsorption step is transferred to the reagent tube. The resin in the resin adsorption device is rinsed with washing liquid, and the washing liquid is recovered into the reagent tube, thus the target protein can be recovered.

[0061] Furthermore, a limiting groove for the reagent tube cap is provided between several reagent tube placement holes 45 and the edge of the upper cover plate 41. The width of the limiting groove is consistent with the connection part of the reagent tube, which is the part that connects the reagent tube and the cap. The limiting groove can be well matched with the currently capped reagent tubes. After the reagent tube is opened, the cap of the reagent tube is limited to the limiting groove, preventing the reagent tube cap from covering the tube opening when transferring the resin adsorption device, thus avoiding interference with the insertion of the resin adsorption device into the reagent tube.

[0062] Furthermore, in this embodiment of the application, the distance between the top cover plate 41 and the bottom plate of the base 42 is greater than the height of the reagent tube.

[0063] Furthermore, the upper cover plate 41 can be further designed so that it and the base 42 can be installed by interlocking, or the upper cover plate 41 can slide horizontally into the base 42. Any improvements to the installation method between the upper cover plate 41 and the base 42 are within the scope of protection of this application. Furthermore, support legs or folding legs can be installed below the upper cover plate 41 to facilitate the separate fixing of the upper cover plate 41.

[0064] Furthermore, the waste liquid tank 44 of this application can be part of the base 42, or it can be set separately from the base 42 and can be moved and placed inside the base 42 or under the upper cover plate in the form of a waste liquid tray.

[0065] Furthermore, the upper sieve plate 21 is larger than the lower sieve plate 22, and the filter sieve plate 34 is larger than the upper sieve plate 21. The mesh size of the upper sieve plate 21 ranges from 15 to 30 mesh, the lower sieve plate 22 ranges from 15 to 30 mesh, and the filter sieve plate 34 ranges from 20 to 50 mesh. This application does not limit the specific aperture of the sieve plates; it can be set according to actual conditions. All inventive designs regarding the aperture of the sieve plates are within the protection scope of this application.

[0066] Furthermore, for example, when desorbing the resin, water is usually used first, followed by alcohol-water elution, with the concentration of alcohol gradually increased. At the same time, rational reactions or chromatography (TLC, polyamide plates, HPLC, etc.) are used as guidance to investigate the effects of the selection, concentration, and amount of the eluent.

[0067] Eluents such as methanol, ethanol, acetone, and ethyl acetate are commonly used and should meet two basic requirements: first, they should be able to swell the macroporous adsorbent; second, they should easily dissolve the adsorbate. Finally, weakly acidic substances can be desorbed using an alkali, while weakly basic substances are better desorbed in an acidic solvent.

[0068] The beneficial effects of the embodiments of this application are as follows:

[0069] This resin adsorption device also integrates multiple functions such as a fixing base, waste liquid tank, and reagent tube placement holes, highly concentrating the necessary equipment for the resin adsorption process, thus achieving an integrated resin adsorption device. The waste liquid tank can recycle sample waste liquid. Several reagent tube placement holes are provided with limiting grooves between the edge of the upper cover plate to limit the reagent tube caps. The limiting grooves are designed to work well with the currently capped reagent tubes. After the reagent tube is opened, the cap of the reagent tube is limited to the limiting groove, preventing the reagent tube cap from covering the tube opening when transferring the resin adsorption device, thus avoiding interference with the insertion of the resin adsorption device into the reagent tube.

[0070] Unless otherwise specifically stated, the relative arrangement, numerical expressions, and values ​​of the components and steps described in these embodiments do not limit the scope of this application. It should also be understood that, for ease of description, the dimensions of the various parts shown in the drawings are not drawn to actual scale. Techniques, methods, and devices known to those skilled in the art may not be discussed in detail, but where appropriate, such techniques, methods, and devices should be considered part of the specification. In all examples shown and discussed herein, any specific values ​​should be interpreted as merely exemplary and not as limitations. Therefore, other examples of exemplary embodiments may have different values. It should be noted that similar reference numerals and letters in the following drawings denote similar items; therefore, once an item is defined in one drawing, it need not be further discussed in subsequent drawings. In the description of this application, it should be understood that the orientation or positional relationship indicated by directional terms such as "front, back, up, down, left, right", "horizontal, vertical, horizontal" and "top, bottom" is usually based on the orientation or positional relationship shown in the accompanying drawings, and is only for the convenience of describing this application and simplifying the description. Unless otherwise stated, these directional terms do not indicate or imply that the device or element referred to must have a specific orientation or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation on the scope of protection of this application; the directional terms "inner" and "outer" refer to the inner and outer contours relative to the outline of each component itself.

[0071] For ease of description, spatial relative terms such as "above," "on top of," "on the upper surface of," "above," etc., are used herein to describe the spatial positional relationship of a device or feature as shown in the figures to other devices or features. It should be understood that spatial relative terms are intended to encompass different orientations in use or operation beyond the orientation of the device as described in the figures. For example, if the device in the figures were inverted, a device described as "above" or "on top of" other devices or structures would subsequently be positioned as "below" or "under" other devices or structures. Thus, the exemplary term "above" can include both "above" and "below." The device may also be positioned in other different ways (rotated 90 degrees or in other orientations), and the spatial relative descriptions used herein will be interpreted accordingly.

[0072] Furthermore, it should be noted that the use of terms such as "first" and "second" to define components is merely for the purpose of distinguishing the corresponding components. Unless otherwise stated, the above terms have no special meaning and therefore cannot be construed as limiting the scope of protection of this application.

[0073] The above description is merely a preferred embodiment of this utility model and is not intended to limit the utility model. Various modifications and variations can be made to this utility model by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. A resin adsorption device, characterized in that: The adsorption device includes a chromatography tube (1) and a filter assembly (2). The chromatography tube (1) includes an inlet (11) and an outlet (12). The outlet (12) has several conical truncated cones (13) with decreasing diameters along its length. The filter assembly (2) includes an upper sieve plate (21) and a lower sieve plate (22). The upper sieve plate (21) and the lower sieve plate (22) are respectively placed at the junction of the conical truncated cones (13). The upper sieve plate (21) and the lower sieve plate (22) form a storage space.

2. The resin adsorption device according to claim 1, characterized in that: The resin adsorption device also includes a filter inner tube (3) that can be placed in the chromatography tube (1). The bottom of the filter inner tube (3) is provided with a filter sieve plate (34), and the upper end of the filter inner tube (3) is provided with a tube beam (31) that is easy to hold.

3. The resin adsorption device according to claim 2, characterized in that: A gap is provided between the outer wall of the filter inner tube (3) and the inner wall of the chromatography tube (1).

4. The resin adsorption device according to claim 2, characterized in that: The tube beam section (31) has a ring structure, and a support column (32) is provided on the lower end face of the tube beam section (31). The support column (32) can support the upper end face of the chromatography tube (1).

5. The resin adsorption device according to claim 2, characterized in that: The resin adsorption device also includes a fixing seat (4), which includes an upper cover plate (41) and a base (42). The upper cover plate (41) is provided with a plurality of chromatography tube placement holes (43).

6. The resin adsorption device according to claim 5, characterized in that: A waste liquid tank (44) is provided below the plurality of chromatography tube placement holes (43).

7. The resin adsorption device according to claim 5, characterized in that: A reagent tube placement hole (45) is provided next to the chromatography tube placement hole (43).

8. The resin adsorption device according to claim 7, characterized in that: A limiting groove (46) is provided between the plurality of reagent tube placement holes (45) and the edge of the upper cover plate (41). The width of the limiting groove (46) is consistent with the connecting part of the reagent tube. The connecting part is the part that connects the reagent tube and the tube cap.

9. The resin adsorption device according to claim 7, characterized in that: The distance between the upper cover plate (41) and the bottom plate of the base (42) is greater than the height of the reagent tube.

10. The resin adsorption device according to claim 7, characterized in that: The upper sieve plate (21) is larger than the lower sieve plate (22). The mesh size of the upper sieve plate (21) is 15-30 mesh, the mesh size of the lower sieve plate (22) is 15-30 mesh, and the mesh size of the filter sieve plate (34) is 20-50 mesh.

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