Negative pressure type fetal calf serum filtering device

By employing a wiping strip and rotating ring structure in the negative pressure fetal bovine serum filtration device, the problem of filter clogging is solved, enabling online cleaning of the filter and ensuring filtration cycle and safety.

CN223930840UActive Publication Date: 2026-02-24NANJING SHENGHANG BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202520328092.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-02-27
Publication Date
2026-02-24
Estimated Expiration
2035-02-27

AI Technical Summary

Technical Problem

In existing technologies, the filter screen is prone to clogging when extracting fetal bovine plasma under negative pressure, which leads to a longer filtration cycle, more complex disinfection process, and a risk of contamination.

Method used

A negative pressure fetal bovine serum filtration device was designed. By installing a wiping strip and a rotating ring structure on the outside of the filter screen, the rotating ring is driven to rotate by the sliding of the plug ring during negative pressure suction. The wiping strip scrapes the outer wall of the filter screen to remove clogging impurities, thus avoiding the need for disassembly and cleaning of the filter screen.

Benefits of technology

It enables online cleaning of the filter, avoiding problems such as prolonged filtration cycles and contamination caused by filter clogging, and ensuring the safety and efficiency of filtration.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a negative pressure type fetal calf serum filtering device which comprises a filtering barrel, an adsorption pipe opening is fixedly installed at the lower end of the filtering barrel, a table-shaped channel is fixedly installed in the adsorption pipe opening, an outer cover is fixedly installed at the lower end opening of the table-shaped channel, a supplementing channel is formed between the outer cover and the upper end opening of the adsorption pipe opening, and a plug ring is vertically arranged in the supplementing channel in a sliding mode. A filter screen cover with a downward opening is fixedly mounted at the upper end opening of the outer cover, and a rotating ring which is pushed by the plug ring to rotate and move is arranged on the side wall of the filter screen cover. According to the negative pressure type fetal calf serum filtering device provided by the utility model, the plug ring downwards slides in the supplementing channel, so that the rotating ring is driven to rotate, and the wiping strip is used for circumferentially scraping the outer side wall of the filter screen cover to remove plasma impurities blocked on the filter screen cover, so that the filter screen cover recovers a normal filtering function, the filter screen cover does not need to be taken down for cleaning, and the operation is simple and convenient. Therefore, the problem of pollution accompanied by disassembly and assembly of the filter barrel is avoided, and the filtering period and the filtering safety can also be guaranteed.
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Description

Technical Field

[0001] This utility model relates to the field of serum filtration equipment technology, and more specifically to a negative pressure fetal bovine serum filtration device. Background Technology

[0002] The preparation of fetal bovine serum requires the removal of fibrinogen and blood cells from the plasma, and the separation of a pale yellow transparent liquid or finger fibrin. A sterile filtration system is usually used to filter the fetal bovine plasma.

[0003] According to the publication (announcement) number: CN220530833U, the publication (announcement) date: 2024-02-27, a fetal bovine serum filter with multiple filter cartridges is disclosed.

[0004] In the prior art, including the aforementioned patent, when using negative pressure to extract plasma for filtration, the plasma usually needs to pass through a cylindrical or columnar filter. However, this causes the filter to become clogged, which is inevitable and occurs periodically. This requires staff to remove and clean the filter, which means that when processing large amounts of plasma, a certain amount of time is needed to solve the filter clogging problem and carry out corresponding disinfection procedures, thereby increasing the filtration cycle and also causing contamination problems. Utility Model Content

[0005] The purpose of this invention is to provide a negative pressure fetal bovine serum filtration device to solve the problems mentioned above.

[0006] To achieve the above objectives, this utility model provides the following technical solution:

[0007] A negative pressure fetal bovine serum filtration device includes a filter barrel with an adsorption tube fixedly installed at its lower end, a platform-shaped channel fixedly installed in the adsorption tube, and an outer cover fixedly installed at the lower end of the platform-shaped channel.

[0008] A supplement is formed between the outer cover and the upper port of the adsorption tube, and a plug ring is vertically slidably arranged in the supplement;

[0009] The outer cover has a filter screen with an opening facing downwards fixedly installed at the upper port, and a rotating ring is provided on the side wall of the filter screen, which is driven by the plug ring to rotate. A wiping strip arranged in a circle and abutting against the outer side wall of the filter screen is fixedly installed on the rotating ring.

[0010] Preferably, bristles are fixedly installed on the inner end face of the wiping strip.

[0011] Preferably, a plurality of drive blocks with arc surfaces are fixedly installed on the lower end face of the rotating ring, and a drive column that slides against the arc surface of the drive blocks is fixedly installed on the upper end face of the plug ring.

[0012] Preferably, in the default state, the end of the drive column abuts against the middle of the arc surface.

[0013] Preferably, a plurality of protrusions are fixedly installed on the upper port of the adsorption tube, and a tension spring is fixedly installed between the protrusions and the plug ring.

[0014] Preferably, the upper port of the platform-shaped channel is fixedly installed with a fine channel that communicates and cooperates with the filter screen cover.

[0015] Preferably, the reduced internal pressure of the filter screen compensates for the negative pressure at the lower port of the adsorption tube.

[0016] Preferably, a sedimentation chamber is provided between the channel and the outer cover.

[0017] Preferably, a support plate is fixedly installed in the filter bucket, and the support plate has an arc hole for the wiping strip to slide.

[0018] Preferably, a plurality of first filters that cooperate with the filter cover are fixedly installed on the support plate.

[0019] In the above technical solution, the negative pressure fetal bovine serum filtration device provided by this utility model has the following beneficial effects: by sliding the plug ring downward into the replenishment, the rotating ring is driven to rotate, and the wiping strip is used to circumferentially scrape the outer wall of the filter screen to remove the plasma impurities clogging the filter screen, so that the filter screen can restore its normal filtration function without removing the filter screen for cleaning, thereby avoiding the pollution problems that occur when disassembling and assembling the filter canister, and also ensuring the filtration cycle and filtration safety. Attached Figure Description

[0020] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in this utility model. For those skilled in the art, other drawings can be obtained based on these drawings.

[0021] Figure 1 A schematic diagram of the filter bucket provided in an embodiment of this utility model;

[0022] Figure 2 A schematic diagram of the filter bucket and its inner filter screen cover, platform-shaped channel and adsorption tube opening provided in the embodiment of this utility model, viewed from the right side of the front cross section.

[0023] Figure 3 A front cross-sectional view of the filter bucket and its inner filter screen cover, platform-shaped channel and adsorption tube opening provided in an embodiment of the present utility model;

[0024] Figure 4 for Figure 3 Enlarged view of point A;

[0025] Figure 5 This is a schematic diagram of the assembly of the plug ring and swivel ring provided in an embodiment of the present utility model.

[0026] Explanation of reference numerals in the attached figures:

[0027] 1. Filter barrel; 2. Support plate; 21. First filter screen; 3. Adsorption port; 31. Terraced channel; 32. Fine channel; 33. Outer cover; 34. Sedimentation chamber; 35. Supplement; 4. Filter screen cover; 5. Plug ring; 51. Drive column; 6. Rotary ring; 61. Wiping strip; 62. Drive block. Detailed Implementation

[0028] To enable those skilled in the art to better understand the technical solution of this utility model, the present utility model will be further described in detail below with reference to the accompanying drawings.

[0029] like Figure 1-5 As shown, a negative pressure fetal bovine serum filtration device includes a filter barrel 1 with an adsorption tube 3 fixedly installed at the lower end, a platform-shaped channel 31 fixedly installed in the adsorption tube 3, and an outer cover 33 fixedly installed at the lower end of the platform-shaped channel 31.

[0030] A supplementary 35 is formed between the outer cover 33 and the upper port of the adsorption tube 3, and a plug ring 5 is vertically slidably arranged in the supplementary 35;

[0031] A filter screen cover 4 with an opening facing downward is fixedly installed on the upper port of the outer cover 33, and a rotating ring 6 is provided on the side wall of the filter screen cover 4, which is driven by the plug ring 5 to rotate. A wiping strip 61 arranged in a circle and abutting against the outer side wall of the filter screen cover 4 is fixedly installed on the rotating ring 6.

[0032] Specifically, the filter barrel 1 is existing technology, and the lower port of the adsorption pipe 3 located outside the barrel is connected to a negative pressure suction pump. The installation and connection position of the negative pressure liquid pump and the power to meet the suction power are also existing technologies, and will not be described in detail here.

[0033] Furthermore, multiple connecting blocks are fixedly installed between the lower port of the platform-shaped channel 31 and the inner wall of the adsorption tube 3, so as not to interfere with the connection of the supplement 35 to the lower port of the adsorption tube 3. The upper end of the outer cover 33 is higher than the upper port of the adsorption tube 3, so that the area above the stopper ring 5 has room to move. Rubber rings are fixedly installed on the inner and outer rings of the stopper ring 5, so as to increase and supplement the piston effect during the movement of the 35.

[0034] Furthermore, the filter screen 4 is used to filter unwanted substances from the blood plasma. Its pore size is existing technology and will not be described in detail here. The filter screen 4 and the outer cover 33 are detachably connected by bolts and nuts.

[0035] Furthermore, the horizontal cross-section of the wiping strip 61 is arc-shaped, which is intended to increase the contact area between the inner wall of the wiping strip 61 and the outer wall of the filter screen 4.

[0036] Negative pressure is applied to the platform-shaped channel 31 through the adsorption port 3, causing the filter screen 4 to draw plasma from the filter tank 1. The filtered serum is discharged and collected from the adsorption port 3. Meanwhile, the stopper ring 5 slides down into the replenishment 35, causing the rotating ring 6 to rotate. The wiping strip 61 is used to circumferentially scrape the outer wall of the filter screen 4 to remove the plasma impurities clogging the filter screen 4, allowing the filter screen 4 to restore its normal filtration function. There is no need to remove the filter screen 4 for cleaning, thus avoiding the contamination problems that occur when disassembling and assembling the filter tank 1, and ensuring the filtration cycle and filtration safety.

[0037] As a further embodiment of this utility model, bristles are fixedly installed on the inner end face of the wiping strip 61.

[0038] Specifically, the bristles can be nylon bristles or elastic metal bristles; the materials used are existing technologies and will not be elaborated upon here.

[0039] The brush bristles enhance the ability to wipe the pores on the surface of the filter screen 4, resulting in better cleaning and unclogging.

[0040] As another embodiment provided by this utility model, a plurality of drive blocks 62 with arc surfaces are fixedly installed on the lower end face of the rotating ring 6, and a drive column 51 that slides against the arc surface of the drive block 62 is fixedly installed on the upper end face of the plug ring 5.

[0041] Specifically, the filter screen 4 does not have holes near the lower port, in order to leave an annular notch for installing the torsion spring. The other end of the torsion spring is fixedly connected to the inner wall of the rotating ring 6, so that the rotating ring 6 has the ability to reset, and the torsion spring is kept in storage by default.

[0042] The drive pin 51 slides towards the lower end of the arc surface (i.e., the lower end of the drive block 62) by moving the stop ring 5 downward, and the rotating ring 6 rotates as the torsion spring returns to its original position.

[0043] As another embodiment further provided by this utility model, the end of the drive column 51 in the default state abuts against the middle of the arc surface.

[0044] With the stopper ring 5 moved to the default state, the drive column 51 is located at the upper end of the arc surface (i.e., the end of the drive column 51 is attached to the lower end face of the rotating ring 6). At this time, the wiping strip 61 can be reset and rotated when the filter screen cover 4 is removed (rotating in the opposite direction to the drive block 62). The purpose is to provide another wiping effect during the removal process. Both directions of rotation can replace the adjacent wiping strip 61 in the circumferential direction, so that multiple wiping strips 61 cover the entire outer wall of the filter screen cover 4 for cleaning, reducing the debris remaining on the filter screen cover 4, and also reducing the difficulty of removing and cleaning the filter screen cover 4.

[0045] As another embodiment of this utility model, a plurality of protrusions are fixedly installed on the upper port of the adsorption tube 3, and a tension spring is fixedly installed between the protrusions and the plug ring 5.

[0046] Specifically, a through-protruding rod is fixedly installed on the plug ring 5, and a tension spring is arranged in a ring on the outside of the rod to ensure the moving guide function.

[0047] The tension spring provides the ability for the stopper ring 5 to move downward and reset. The tension spring is in a deformed state by default, and when the rotating ring 6 resets and rotates, it can be accompanied by the tension spring to fully reset.

[0048] As another embodiment provided in this utility model, a narrow channel 32 that communicates and cooperates with the filter screen cover 4 is fixedly installed at the upper port of the platform channel 31.

[0049] Specifically, the inner wall area of ​​channel 32 is smaller than the cross-sectional area of ​​supplement 35.

[0050] The upper port of the narrow channel 32 extends into the filter screen 4, which facilitates the suction of serum inside the filter screen 4 by the platform-shaped channel 31, ensuring the effective delivery of serum.

[0051] As another embodiment further provided in this utility model, the filter screen 4 with reduced internal pressure compensates for the negative pressure at the lower port of the adsorption tube 3 by supplementing 35.

[0052] By supplementing the suction with 35, and with the small inner wall area of ​​the channel 32, the stopper ring 5 has a significant displacement ability. When the filter screen 4 is blocked, the missing air pressure in the adsorption tube 3 is drawn from the supplementing 35. As a result, the stopper ring 5 moves down under the negative pressure suction, and the rotating ring 6 loses its resistance and rotates until the filter screen 4 recovers its pressure. Then, the wiping strip 61 in the middle can be cleaned again.

[0053] As another embodiment of this utility model, a sedimentation chamber 34 is provided between the channel 32 and the outer cover 33.

[0054] By utilizing the truncated surface on the truncated channel 31, the serum can have a certain sedimentation effect, which is used to precipitate and separate the residual impurities in the serum. Later, a brush tool can be used for cleaning to improve the purity of the serum.

[0055] As another embodiment of this utility model, a support plate 2 is fixedly installed in the filter bucket 1, and the support plate 2 is provided with an arc hole for the wiping strip 61 to slide.

[0056] Specifically, the support plate 2 has a circular hole on its axis for installing the filter screen cover 4.

[0057] The upper end of the wiping strip 61 is provided with a sliding limit through the arc hole to ensure the vertical stability of the wiping strip 61.

[0058] As another embodiment of this utility model, a plurality of first filters 21 that cooperate with the filter cover 4 are fixedly installed on the support plate 2.

[0059] Specifically, the first filter 21 is installed in the notch opened on the support plate 2.

[0060] The plasma added to the filter bucket 1 is initially filtered through the first filter screen 21, reducing the workload of the filter screen cover 4.

[0061] Working principle: Negative pressure is applied to the platform-shaped channel 31 through the adsorption port 3, and the filter screen 4 draws plasma from the filter bucket 1. The filtered serum is discharged and collected from the adsorption port 3. When the filter screen 4 becomes clogged, the missing air pressure in the adsorption port 3 is drawn from the replenishment 35. As a result, the stopper ring 5 slides downward into the replenishment 35 under the negative pressure, which causes the rotating ring 6 to lose its resistance and rotate. The wiping strip 61 is used to scrape the outer wall of the filter screen 4 in a circumferential manner to remove the plasma impurities that clog the filter screen 4, so that the filter screen 4 can restore its normal filtration function without having to remove the filter screen 4 for cleaning.

[0062] The foregoing description only illustrates certain exemplary embodiments of the present invention. Undoubtedly, those skilled in the art can modify the described embodiments in various ways without departing from the spirit and scope of the present invention. Therefore, the above drawings and descriptions are illustrative in nature and should not be construed as limiting the scope of protection of the claims of the present invention.

Claims

1. A negative pressure fetal bovine serum filtration device, characterized in that, The filter bucket (1) includes an adsorption tube (3) fixedly installed at the lower end, wherein a platform-shaped channel (31) is fixedly installed in the adsorption tube (3), and an outer cover (33) is fixedly installed at the lower end of the platform-shaped channel (31). The outer cover (33) and the upper port of the adsorption tube (3) form a supplement (35), and a plug ring (5) is vertically slidably arranged in the supplement (35); The outer cover (33) is fixedly installed with a filter screen cover (4) with the opening facing downward, and a rotating ring (6) is provided on the side wall of the filter screen cover (4) and rotated by the push of the plug ring (5). A wiping strip (61) arranged in a circle and abutting against the outer side wall of the filter screen cover (4) is fixedly installed on the rotating ring (6).

2. The negative pressure fetal bovine serum filtration device according to claim 1, characterized in that, The inner end face of the wiping strip (61) is fixedly equipped with bristles.

3. The negative pressure fetal bovine serum filtration device according to claim 1, characterized in that, The lower end face of the rotating ring (6) is fixedly installed with a plurality of drive blocks (62) with arc surfaces, and the upper end face of the plug ring (5) is fixedly installed with a drive column (51) that slides against the arc surface of the drive block (62).

4. The negative pressure fetal bovine serum filtration device according to claim 3, characterized in that, In the default state, the end of the drive column (51) abuts against the middle of the arc surface.

5. A negative pressure fetal bovine serum filtration device according to claim 3, characterized in that, Multiple protrusions are fixedly installed on the upper port of the adsorption tube (3), and a tension spring is fixedly installed between the protrusions and the plug ring (5).

6. The negative pressure fetal bovine serum filtration device according to claim 4, characterized in that, The upper port of the platform-shaped channel (31) is fixedly installed with a narrow channel (32) that communicates and cooperates with the filter screen cover (4).

7. A negative pressure fetal bovine serum filtration device according to claim 6, characterized in that, The reduced internal pressure of the filter screen (4) causes supplementary (35) compensation for the negative pressure at the lower port of the adsorption tube (3).

8. A negative pressure fetal bovine serum filtration device according to claim 6, characterized in that, A sedimentation chamber (34) is provided between the channel (32) and the outer cover (33).

9. A negative pressure fetal bovine serum filtration device according to claim 6, characterized in that, A support plate (2) is fixedly installed in the filter barrel (1), and an arc hole is provided on the support plate (2) for the wiping strip (61) to slide.

10. A negative pressure fetal bovine serum filtration device according to claim 9, characterized in that, Multiple first filters (21) that cooperate with the filter cover (4) are fixedly installed on the support plate (2).

Citation Information

Patent Citations

  • Fetal calf serum filter with multiple groups of filter cartridges

    CN220530833U