Mixing device for production of doramectin injection

By combining mechanical rotation, vibration, and pneumatics, the problem of dead zones in the production of doramectin injection has been solved, achieving uniform mixing and efficient production, thus ensuring drug quality and stability.

CN223931238UActive Publication Date: 2026-02-24JIANGXI HEXU BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202520383934.1
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-03-06
Publication Date
2026-02-24
Estimated Expiration
2035-03-06

AI Technical Summary

Technical Problem

Existing mixing devices are prone to creating bottom mixing dead zones in the production of doramectin injection, affecting the uniformity of mixing and leading to a decline in production quality.

Method used

The mixing of doramectin injection solution is achieved by combining mechanical rotation, vibration and pneumatics through structures such as the convex ring on the stirring shaft, stirring rod and air nozzle. The mixing efficiency is improved by using pulsed gas inflation and negative pressure suction to discharge the material, avoiding dead zones in the mixing.

Benefits of technology

This process ensures uniform mixing of doramectin injection raw materials, reduces dead zones in the mixing process, improves production quality, and guarantees drug consistency and stability, meeting drug quality standards.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a material mixing device for doramectin injection production, which comprises a material mixing tank provided with a material inlet and a material outlet, the top of the material mixing tank is fixedly provided with a driving motor, the material mixing tank is rotatably provided with a stirring main shaft, an output shaft of the driving motor is fixedly connected with the top end of the stirring main shaft through a coupler, and the output shaft of the driving motor is fixedly connected with the top end of the stirring main shaft. Convex rings which are arranged at equal intervals are integrally formed on the stirring main shaft, stirring rods which are arranged at equal intervals are slidably mounted on the stirring main shaft, the stirring rods and the convex rings are arranged at intervals, the bottoms of the stirring rods are in contact with the convex rings, a cavity is formed in the stirring main shaft, and air outlet holes which are uniformly distributed are formed in the convex rings. And the air outlet is communicated with the interior of the cavity. According to the doramectin injection raw material mixing device, the raw material mixing effect is jointly completed in various modes of mechanical rotation, vibration, pneumatic operation and the like, so that the mixing efficiency and effect of doramectin injection production raw materials are improved.
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Description

Technical Field

[0001] This utility model relates to the field of mixing technology for the production of doramectin injection, specifically, to a mixing device for the production of doramectin injection. Background Technology

[0002] As the main active ingredient, doramectin is evenly distributed in the injection solution through the mixing process. The precise and consistent content of the active ingredient in each doramectin injection ensures accurate dosage and stable efficacy across different batches and even between different individuals within the same batch during clinical use. For example, in treating parasitic diseases in animals, using the same dose of doramectin for each animal ensures consistent inhibition or eradication of parasites, preventing poor treatment outcomes or overdose in some animals due to uneven drug content. Mixing also maintains uniform physical properties of the injection solution, such as color, transparency, and viscosity. Uniform physical properties not only contribute to the consistency of the injection solution's appearance but are also crucial for its stability during storage and use. Injections with a uniform appearance are more readily accepted by healthcare professionals and users, and also meet pharmaceutical quality standards.

[0003] However, most current mixing devices use a single mixing method, resulting in poor mixing effect for doramectin injection production. Furthermore, most mixing devices are prone to dead zones at the bottom, affecting the uniformity of doramectin injection raw material mixing and leading to a decline in the production quality of doramectin injection. Summary of the Invention

[0004] In view of the problems existing in the prior art, the purpose of this utility model is to provide a mixing device for the production of doramectin injection, so as to solve the problem that the bottom of the existing mixing device is prone to dead corners in mixing and stirring, which affects the uniformity of mixing and leads to a decline in the production quality of doramectin injection.

[0005] To solve the above problems, the present invention adopts the following technical solution;

[0006] A mixing device for producing doramectin injection includes a mixing tank with an inlet and an outlet. A drive motor is fixedly mounted on the top of the mixing tank. A stirring shaft is rotatably mounted on the mixing tank. The output shaft of the drive motor is fixedly connected to the top of the stirring shaft via a coupling. The stirring shaft has equidistantly arranged convex rings integrally formed on it. Equidistantly arranged stirring rods are slidably mounted on the stirring shaft, with the stirring rods spaced apart from the convex rings and their bottoms contacting the convex rings. The stirring shaft has an internal cavity. The convex rings have evenly distributed air vents that communicate with the interior of the cavity. A bottom plug structure is slidably mounted on the bottom of the stirring shaft, with its top extending into the interior of the cavity. A connecting ring is rotatably connected to the stirring shaft via a shaft seal. An air nozzle is fixedly mounted on the connecting ring. The stirring shaft has evenly distributed connecting holes that communicate with the interior of the cavity.

[0007] As a further description of the above technical solution:

[0008] The stirring rod consists of a slip ring and two crossbars integrally formed on the slip ring. The slip ring is slidably connected to the stirring main shaft. The bottom of the slip ring fits against the convex ring and seals the vent hole.

[0009] As a further description of the above technical solution:

[0010] A spring is fixedly connected between the slip ring and the adjacent bottom convex ring.

[0011] As a further description of the above technical solution:

[0012] A pressure relief valve is fixedly installed on the mixing tank.

[0013] As a further description of the above technical solution:

[0014] The bottom plug structure includes a piston rod that is slidably installed at the bottom of the stirring spindle. Two bottom scrapers are integrally formed on the piston rod. A plug rod is integrally formed at the bottom of the piston rod. The bottom end of the plug rod extends to the inside of the discharge port and fits against the inner wall of the discharge port.

[0015] As a further description of the above technical solution:

[0016] The bottom of the scraper is in contact with the inner bottom wall of the mixing tank.

[0017] Compared with existing technologies, the advantages of this utility model are:

[0018] This solution employs a combination of mechanical rotation, vibration, and pneumatic methods to mix the raw materials, thereby improving the mixing efficiency and effectiveness of the raw materials for doramectin injection production. It also avoids the raw materials entering the discharge port before mixing, which would create a mixing dead zone and affect the mixing effect. When discharge is required, the air pressure inside cavity 7 becomes negative, and the piston column 91 is pulled up by suction to expose the discharge port for easy discharge. Attached Figure Description

[0019] Figure 1 This is a frontal sectional view of the present invention.

[0020] Figure 2 This is a front sectional view of the bottom plug structure of this utility model;

[0021] Figure 3 This is a schematic diagram of the connection structure between the stirring shaft and the connecting ring of this utility model;

[0022] Figure 4 This utility model Figure 2 A magnified structural diagram of part A in the middle.

[0023] Explanation of the labels in the diagram:

[0024] 1. Mixing tank; 2. Drive motor; 3. Agitator shaft; 4. Convex ring; 5. Agitator rod; 51. Slip ring; 52. Crossbar; 53. Spring; 6. Pressure relief valve; 7. Cavity; 8. Air outlet; 9. Bottom plug structure; 91. Piston column; 92. Bottom scraper; 93. Plug column; 10. Connecting ring; 11. Air nozzle; 12. Connecting hole. Detailed Implementation

[0025] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model;

[0026] Please see Figure 1-4In this utility model, a mixing device for producing doramectin injection includes a mixing tank 1 with an inlet and an outlet. A drive motor 2 is fixedly installed on the top of the mixing tank 1. A stirring shaft 3 is rotatably installed on the mixing tank 1. The output shaft of the drive motor 2 is fixedly connected to the top of the stirring shaft 3 via a coupling. Equally spaced protruding rings 4 are integrally formed on the stirring shaft 3. Equally spaced stirring rods 5 are slidably installed on the stirring shaft 3. The stirring rods 5 are spaced apart from the protruding rings 4, and the bottom of the stirring rods 5 is parallel to the protruding rings 4. The convex ring 4 contacts the cavity 7 inside the stirring shaft 3. The convex ring 4 has evenly distributed air outlets 8, which are connected to the inside of the cavity 7. A bottom plug structure 9 is slidably installed at the bottom of the stirring shaft 3, and the top of the bottom plug structure 9 extends into the inside of the cavity 7. A connecting ring 10 is rotatably connected to the stirring shaft 3 through a shaft seal. An air nozzle 11 is fixedly installed on the connecting ring 10. The stirring shaft 3 has evenly distributed connecting holes 12, and the air nozzle 11 is connected to the inside of the cavity 7 through the connecting holes 12.

[0027] In this invention, the raw materials for doramectin injection are fed into the mixing tank 1 through the inlet. Then, an external air source is connected via the air nozzle 11, simultaneously powering the motor 2 to rotate the stirring shaft 3. This, in turn, rotates the multiple stirring rods 5 on the stirring shaft 3, mixing the raw materials for doramectin injection in the mixing tank 1. The gas passes through the connecting hole 12 and the cavity 7, and is then ejected through the air outlet 8. Because the bottom of the stirring rod 5 contacts the convex ring 4, the gas discharge requires lifting the stirring rod 5. When the air source is pulsed, it can intermittently drive the stirring. The vibration of rod 5 improves the mixing effect of raw materials for doramectin injection production. At the same time, the sprayed gas can collide and squeeze the raw materials, further improving the mixing effect and preventing the raw materials from entering the cavity 7 through the air outlet 8. After mixing, the air source equipment draws air into the cavity 7 to form a negative pressure, and at this time the air outlet 8 is blocked, thereby generating suction on the bottom plug structure 9, causing it to move upward, so that the mixed raw materials can be discharged through the outlet. The mixing of raw materials is completed by a combination of mechanical rotation, vibration and pneumatic methods, thereby improving the mixing efficiency and effect of raw materials for doramectin injection production.

[0028] Please see Figure 1-3 The stirring rod 5 consists of a slip ring 51 and two crossbars 52 integrally formed on the slip ring 51. The slip ring 51 is slidably connected to the stirring shaft 3. The bottom of the slip ring 51 fits against the convex ring 4 and blocks the vent hole 8, thereby controlling the airflow.

[0029] In this invention, when the stirring shaft 3 rotates, it drives the slip ring 51 on it to rotate, and the crossbar 52 rotates around the stirring shaft 3 as the center of rotation, stirring the raw materials. In the initial state, the bottom of the slip ring 51 is attached to the convex ring 4 and blocks the air outlet 8. When air is released from the air outlet 8, the slip ring 51 needs to be lifted up to achieve the purpose of vibration.

[0030] Please see Figure 2 and Figure 3 Among them, a spring 53 is fixedly connected between the slip ring 51 and the adjacent bottom convex ring 4.

[0031] In this invention, the spring 53 provides a downward elastic force to the slip ring 51, which facilitates the downward reset of the slip ring 51, thereby improving the vibration effect.

[0032] Please see Figure 1 Among them, a pressure relief valve 6 is fixedly installed on the mixing tank 1.

[0033] In this invention, the pressure relief valve 6 can discharge excess gas from the mixing tank 1, thus preventing excessive gas pressure in the mixing tank 1.

[0034] Please see Figure 2 The bottom plug structure 9 includes a piston column 91 that is slidably installed at the bottom of the stirring shaft 3. Two bottom scrapers 92 are integrally formed on the piston column 91. A plug column 93 is integrally formed at the bottom of the piston column 91. The bottom end of the plug column 93 extends to the inner side of the discharge port and fits against the inner wall of the discharge port.

[0035] In this invention, by sealing the bottom of the mixing shaft 3 with the piston column 91, the air pressure inside the cavity 7 of the mixing shaft 3 is in a positive pressure and normal pressure state. The piston column 91 moves downward, driving the plug column 93 into the discharge port, which avoids the raw materials entering the discharge port before mixing and causing a mixing dead zone, thus affecting the mixing effect of the raw materials. When it is necessary to discharge the material, the air pressure inside the cavity 7 becomes a negative pressure, and the piston column 91 is pulled up by suction, thereby exposing the discharge port and facilitating the discharge.

[0036] Please see Figure 1 and Figure 2 The bottom of the bottom scraper 92 is in contact with the inner bottom wall of the mixing tank 1.

[0037] In this invention, the bottom scraper 92 can stir and mix the raw materials at the bottom of the mixing tank 1, thereby increasing the mixing range, reducing dead zones, and improving the mixing effect.

[0038] The above description is merely a preferred embodiment of this utility model; however, the protection scope of this utility model is not limited thereto. Any equivalent substitutions or modifications made by those skilled in the art within the technical scope disclosed in this utility model, based on the technical solution and its improved concept, should be included within the protection scope of this utility model.

Claims

1. A mixing device for producing doramectin injection, comprising a mixing tank (1) having an inlet and an outlet, characterized in that: A drive motor (2) is fixedly installed on the top of the mixing tank (1). A stirring spindle (3) is rotatably installed on the mixing tank (1). The output shaft of the drive motor (2) is fixedly connected to the top of the stirring spindle (3) via a coupling. Equally spaced protruding rings (4) are integrally formed on the stirring spindle (3). Equally spaced stirring rods (5) are slidably installed on the stirring spindle (3). The stirring rods (5) are spaced apart from the protruding rings (4), and the bottom of the stirring rods (5) contacts the protruding rings (4). A cavity (7) is provided inside the stirring spindle (3). The convex ring (4) is provided with evenly distributed air outlets (8), which are connected to the interior of the cavity (7). The bottom of the stirring shaft (3) is slidably installed with a bottom plug structure (9), the top of which extends into the interior of the cavity (7). The stirring shaft (3) is rotatably connected with a connecting ring (10) through a shaft seal. An air nozzle (11) is fixedly installed on the connecting ring (10). The stirring shaft (3) is provided with evenly distributed connecting holes (12), and the air nozzle (11) is connected to the interior of the cavity (7) through the connecting holes (12).

2. The mixing device for producing doramectin injection according to claim 1, characterized in that: The stirring rod (5) consists of a slip ring (51) and two crossbars (52) integrally formed on the slip ring (51). The slip ring (51) is slidably connected to the stirring main shaft (3). The bottom of the slip ring (51) fits against the convex ring (4) and blocks the vent (8).

3. The mixing device for producing doramectin injection according to claim 2, characterized in that: A spring (53) is fixedly connected between the slip ring (51) and the adjacent bottom protrusion ring (4).

4. The mixing device for producing doramectin injection according to claim 1, characterized in that: A pressure relief valve (6) is fixedly installed on the mixing tank (1).

5. The mixing device for producing doramectin injection according to claim 1, characterized in that: The bottom plug structure (9) includes a piston column (91) that is slidably installed at the bottom of the stirring spindle (3). Two bottom scrapers (92) are integrally formed on the piston column (91). A plug column (93) is integrally formed at the bottom of the piston column (91). The bottom end of the plug column (93) extends to the inside of the discharge port and fits against the inner wall of the discharge port.

6. The mixing device for producing doramectin injection according to claim 5, characterized in that: The bottom of the bottom scraper (92) is in contact with the inner bottom wall of the mixing tank (1).