Nucleic acid synthesizer

Abstract

The utility model relates to a nucleic acid synthesizer which comprises a synthesizer main body and a folding structure, when a person rotates the placing plate upwards, the rotating plate rotates horizontally from the vertical direction, after the rotating plate is horizontal, the placing plate can be located at the horizontal position, the person moves the placing plate downwards, the upper end of the oval hole makes contact with the fixing shaft, the rotating plate cannot rotate, and the placing plate is fixed at the horizontal position; at the moment, tools needing to be used can be placed on the placing plate, then when a person carries out nucleic acid synthesis through the synthesizer main body, the person can directly take the needed tools on the placing plate for use, when the person does not need to carry out nucleic acid synthesis, the person moves the placing plate upwards, and the lower end of the oval hole makes contact with the fixing shaft. At the moment, the personnel can rotate the placement plate from the horizontal state to the vertical state to fold the placement plate, and an additional working surface is provided through the foldable placement plate, so that an operator can conveniently take required tools at any time, and the synthesis efficiency of nucleic acid is improved.

Description

Technical Field

[0001] This utility model relates to the technical field of equipment for nucleic acid synthesis, specifically to a nucleic acid synthesizer. Background Technology

[0002] A nucleic acid synthesizer is a device used for the automated synthesis of nucleotide sequences, primarily in fields such as biotechnology, medical research, and diagnostics. Through chemical synthesis methods, nucleic acid synthesizers can precisely construct DNA or RNA molecules according to user-specified sequences. Nucleic acid synthesizers are mainly based on the phosphotriester method, a highly efficient and accurate solid-phase synthesis method. The core of this method is to immobilize the growing nucleic acid chain using a solid support (such as a controlled-flow column or glass beads with controllable pore size) and gradually add nucleotide units through a series of chemical reaction steps.

[0003] However, in the existing technology for nucleic acid drug synthesis, operators use auxiliary tools such as reaction tubes, sealing gaskets, connecting tubes, and filters. These auxiliary tools are placed in other locations, which makes it very troublesome for personnel to move back and forth to retrieve them when they need to use these auxiliary tools, thus reducing the efficiency of nucleic acid synthesis. Utility Model Content

[0004] The main purpose of this invention is to provide a nucleic acid synthesizer that solves the problems mentioned above.

[0005] To achieve the above objectives, this utility model provides a nucleic acid synthesizer, including a synthesizer body and a folded structure;

[0006] The folding structure is located on one side of the synthesizer body. The folding structure includes a folding component and a placement plate. The folding component includes two fixed plates, two rotating plates, and a fixed shaft. The two fixed plates are respectively connected to the side wall of the synthesizer body. The fixed shaft is located between the upper ends of the two fixed plates. The inner ends of the two rotating plates are respectively sleeved on the fixed shaft through elliptical holes. The placement plate is located at the upper ends of the two rotating plates.

[0007] The aforementioned beneficial effects are as follows: When the operator rotates the placement plate upwards, it changes from a vertical to a horizontal position. Once the plate is horizontal, the placement plate will also be in a horizontal position. Moving the plate downwards prevents the rotation of the plate from proceeding, fixing it in a horizontal position. Tools can then be placed on the plate. When synthesizing nucleic acids using the synthesizer, the operator can directly retrieve the necessary tools from the plate. When not in use, the operator moves the plate upwards until the lower end of the elliptical hole contacts the fixed shaft, allowing the plate to rotate from a horizontal to a vertical position and fold. This foldable plate provides an additional working surface, facilitating easy access to tools and improving nucleic acid synthesis efficiency.

[0008] In a preferred embodiment, the folding member has two sets, and the two sets of folding members are respectively disposed on the side wall of the synthesizer body.

[0009] A preferred embodiment is that the upper end of the placement plate is provided with a groove.

[0010] A preferred embodiment further includes a storage structure disposed at the upper end of the placement plate. The storage structure includes a connecting block and clamping members. The upper end of the connecting block is provided with a plurality of storage holes, and the clamping members are respectively disposed in the plurality of storage holes.

[0011] In a preferred embodiment, the clamping member includes four spring structures and four arc-shaped plates, the four spring structures being arranged along the circumferential direction of the storage hole, and the four arc-shaped plates being respectively connected to the four spring structures. Attached Figure Description

[0012] The present invention will now be described in further detail with reference to the accompanying drawings and specific embodiments.

[0013] Figure 1 This is a schematic diagram of the structure of a nucleic acid synthesizer according to the present invention;

[0014] Figure 2 This is a schematic diagram of the structure of a nucleic acid synthesizer according to the present invention, showing a partial side sectional view and a plan view.

[0015] Figure 3 This is a partial structural schematic diagram of a nucleic acid synthesizer according to the present invention;

[0016] Figure 4 yes Figure 3 A magnified structural diagram of area A in the middle.

[0017] In the diagram: 10. Main body of the synthesizer; 20. Folding structure; 30. Folding component; 21. Placement plate; 31. Fixing plate; 32. Rotating plate; 33. Fixing shaft; 34. Elliptical hole; 35. Groove; 40. Storage structure; 41. Connecting block; 42. Clamping component; 43. Storage hole; 421. Spring structure; 422. Arc plate. Detailed Implementation

[0018] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Many specific details are set forth in the following description to provide a full understanding of the present invention. However, the present invention may also be implemented in other ways different from those described herein. Those skilled in the art can make similar extensions without departing from the spirit of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0019] This utility model provides a nucleic acid synthesizer, including a synthesizer body 10 and a folded structure 20;

[0020] The folding structure 20 is disposed on one side of the synthesizer body 10. The folding structure 20 includes a folding component 30 and a placement plate 21. The folding component 30 includes two fixing plates 31, two rotating plates 32, and a fixing shaft 33. The two fixing plates 31 are respectively connected to the side wall of the synthesizer body 10. The fixing shaft 33 is disposed between the upper ends of the two fixing plates 31. The inner ends of the two rotating plates 32 are respectively sleeved on the fixing shaft 33 through elliptical holes 34. The placement plate 21 is disposed at the upper end of the two rotating plates 32.

[0021] During operation, the operator rotates the placement plate 21 upwards, causing the rotating plate 32 to rotate from vertical to horizontal. Once the rotating plate 32 is horizontal, the placement plate 21 will be in a horizontal position. The operator then moves the placement plate 21 downwards until the upper end of the elliptical hole 34 contacts the fixed shaft 33. At this point, the rotating plate 32 cannot rotate, and the placement plate 21 is fixed in a horizontal position. The necessary tools can then be placed on the placement plate 21. When the operator performs nucleic acid synthesis through the synthesizer body 10, the necessary tools can be directly retrieved from the placement plate 21. When not in use, the operator moves the placement plate 21 upwards until the lower end of the elliptical hole 34 contacts the fixed shaft 33. At this point, the operator can rotate the placement plate 21 from a horizontal to a vertical position and fold it. The foldable placement plate 21 provides an additional working surface, making it easy for the operator to access the necessary tools at any time, thereby improving the efficiency of nucleic acid synthesis.

[0022] Preferably, the folding member 30 has two sets, and the two sets of folding members 30 are respectively disposed on the side wall of the synthesizer body 10.

[0023] Preferably, the upper end of the placement plate 21 is provided with a groove 35.

[0024] The groove 35 prevents tools from falling off the placement plate 21.

[0025] Preferably, it further includes a storage structure 40, which is disposed on the upper end of the placement plate 21. The storage structure 40 includes a connecting block 41 and a clamping member 42. The upper end of the connecting block 41 is provided with a plurality of storage holes 43, and the clamping member 42 is disposed in each of the plurality of storage holes 43.

[0026] When the placement plate 21 is in a horizontal position, after placing the tool on the placement plate 21, multiple reagent bottles can be placed into multiple storage holes 43 for storage. After multiple reagent bottles are placed into storage holes 43, the reagent bottles are clamped by clamping members 42, so that the reagent bottles can be stably stored in storage holes 43, ensuring the stability of these reagent bottles during the subsequent placement process into the synthesizer body 10, and avoiding reagent bottles from being disordered or tipped over.

[0027] Preferably, the clamping member 42 includes four spring structures 421 and four arc-shaped plates 422. The four spring structures 421 are arranged along the circumferential direction of the storage hole 43, and the four arc-shaped plates 422 are respectively connected to the four spring structures 421.

[0028] When the reagent bottle is placed into the storage hole 43, the four arc plates 422 will move outward respectively, and the four spring structures 421 will contract. When the reagent bottle is completely placed into the storage hole 43, the four spring structures 421 will extend, and the four arc plates 422 will clamp the reagent bottle, so that the reagent bottle can be stably stored in the storage hole 43, so as to facilitate the subsequent placement of the reagent bottle into the main body 10 of the synthesizer.

[0029] Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. All other embodiments obtained by those skilled in the art based on the embodiments of this utility model without inventive effort are within the scope of protection of this utility model.

Claims

1. A nucleic acid synthesizer, characterized in that, include: Synthesizer body (10); The folding structure (20) is located on one side of the synthesizer body (10). The folding structure (20) includes a folding component (30) and a placement plate (21). The folding component (30) includes two fixed plates (31), two rotating plates (32), and a fixed shaft (33). The two fixed plates (31) are respectively connected to the side wall of the synthesizer body (10). The fixed shaft (33) is located between the upper ends of the two fixed plates (31). The inner ends of the two rotating plates (32) are respectively sleeved on the fixed shaft (33) through elliptical holes (34). The placement plate (21) is located at the upper end of the two rotating plates (32).

2. The nucleic acid synthesizer according to claim 1, characterized in that, The folding member (30) has two sets, and the two sets of folding members (30) are respectively disposed on the side wall of the synthesizer body (10).

3. The nucleic acid synthesizer according to claim 1, characterized in that, The upper end of the placement plate (21) is provided with a groove (35).

4. The nucleic acid synthesizer according to claim 1, characterized in that, It also includes a storage structure (40), which is disposed at the upper end of the placement plate (21). The storage structure (40) includes a connecting block (41) and a clamping member (42). The upper end of the connecting block (41) is provided with a plurality of storage holes (43), and the clamping member (42) is disposed in each of the plurality of storage holes (43).

5. The nucleic acid synthesizer according to claim 4, characterized in that, The clamping member (42) includes four spring structures (421) and four arc plates (422). The four spring structures (421) are arranged along the circumferential direction of the storage hole (43), and the four arc plates (422) are respectively connected to the four spring structures (421).

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