Detection device for special biological resources

By integrating X-ray microtomography and Raman spectroscopy, a multimodal detection device has been developed, solving the problem of non-destructive testing of special biological resources and achieving non-destructive testing and protection. It is suitable for customs and special locations.

CN223940793UActive Publication Date: 2026-02-24BEIJING HANGXING MACHINERY MFG CO LTD +1
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Patent Information

Application Number
CN202423154683.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-20
Publication Date
2026-02-24
Estimated Expiration
2034-12-20

AI Technical Summary

Technical Problem

Existing technologies struggle to perform non-destructive testing on special biological resources, especially when there is a high degree of similarity in tissue structure, atomic number, and electron density, making it difficult to distinguish and differentiate them.

Method used

A multimodal detection device integrating X-ray microtomography and Raman spectroscopy was designed. The Raman spectrometer can switch between X-ray detection and Raman spectroscopy detection by rotating components. Combined with a radiation protection shell, it protects the operator and the environment, thus achieving non-destructive testing.

Benefits of technology

It enables non-destructive testing of special biological resources, accurately identifies and protects these resources, avoids damage to goods, and is suitable for customs and other special locations.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to a detection device for special biological resources, belongs to the technical field of detection of the special biological resources, and solves the problem that the special biological resources are difficult to be subjected to nondestructive detection in the prior art. The detection device comprises a radiation protection shell, a mounting platform, a rotary table, a radiation source, a detector, a Raman spectrometer and a rotating assembly, wherein the rotary table is rotatably arranged on the mounting platform; the radiation source and the detector are oppositely arranged on the two sides of the mounting platform; the radiation protection shell is internally provided with a protection cavity used for X-ray protection, the rotating assembly drives the Raman spectrometer to be switched between a first position and a second position, and the Raman spectrometer collects Raman spectrum data of a target object when the Raman spectrometer is located at the first position; the Raman spectrometer is located inside the protective chamber when in the second position. According to the detection device disclosed by the utility model, an X-ray microscopic tomography analysis technology and a Raman spectrum analysis technology are fused, and nondestructive detection can be carried out on special biological resources.
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Description

Technical Field

[0001] This utility model relates to the field of special biological resource detection technology, and in particular to a detection device for special biological resources. Background Technology

[0002] Special biological resources include biological products, bacterial and viral strains, human tissues, blood and blood products, etc. Currently, there are no mature products available to meet the customs requirements for non-destructive testing of these special biological resources.

[0003] Currently, non-destructive testing of special biological resources during customs clearance is mainly achieved through computed tomography (CT). CT combines X-ray imaging and computer reconstruction techniques. Through X-ray tomographic analysis and reconstruction, it can obtain the material's structure, as well as intrinsic characteristics such as atomic number and electron density. CT is widely used for rapid non-destructive testing of passenger luggage, express parcels, etc., and can be used to quickly identify organic and inorganic substances, as well as flammable and explosive materials, dangerous goods, and taxable items such as milk powder and luxury goods. However, some special biological resources exhibit high similarity in structure, atomic number, and electron density, making it difficult to distinguish between them.

[0004] Another non-destructive testing method is Raman spectroscopy. Raman spectroscopy is based on the interaction between light and the chemical bonds within a material, and can provide detailed information on the chemical structure, phase and morphology, crystallinity, and molecular interactions of the sample. Raman spectroscopy is an intrinsic detection method, but it has significant limitations regarding the container used for the sample; a transparent container must be used, otherwise it will affect the detection of the substances inside the container.

[0005] Both tomography and Raman spectroscopy are non-destructive testing techniques with their own advantages and disadvantages. Relying on only one of these techniques cannot meet the needs of testing special biological resources. Utility Model Content

[0006] Based on the above analysis, the present invention aims to provide a detection device for special biological resources, thereby solving the problem that the prior art is unable to perform non-destructive testing on special biological resources.

[0007] This utility model embodiment provides a detection device for special biological resources, characterized in that the detection device includes: a radiation protection shell and an installation platform, a turntable, a radiation source, a detector, a Raman spectrometer, and a rotating assembly disposed inside the radiation protection shell.

[0008] The turntable is rotatably mounted on the mounting platform and is used to carry the item to be inspected; the X-ray source and the detector are arranged opposite to each other on both sides of the mounting platform to perform X-ray inspection on the item on the turntable.

[0009] The radiation protection enclosure has a protective chamber inside for X-ray protection;

[0010] The rotating assembly includes a first motor and a drive shaft. The shaft of the first motor is connected to the drive shaft, and the drive shaft is fixedly connected to the Raman spectrometer. The first motor drives the Raman spectrometer to switch between a first position and a second position via the drive shaft. In the first position, the Raman spectrometer collects Raman spectral data of the target item; in the second position, the Raman spectrometer is located inside the protective chamber.

[0011] Based on a further improvement of the above device, a through hole is provided on the top surface of the protective chamber. When the first Raman spectrometer is in the first position, it is above the turntable. When the Raman spectrometer moves from the first position to the second position, it enters the protective chamber through the through hole.

[0012] Based on a further improvement of the above device, the first motor and the drive shaft are disposed within the protective chamber, and the drive shaft is fixedly connected to the Raman spectrometer via a connector.

[0013] One end of the connector is fixedly connected to the drive shaft, and the other end of the connector passes through the through hole and is fixedly connected to the Raman spectrometer.

[0014] Based on further improvements to the above-mentioned device, the motor and the drive shaft are connected by a belt or chain.

[0015] Based on further improvements to the above-mentioned device, a protective cover is provided on the outer wall of the Raman spectrometer. When the Raman spectrometer is in the second position, the protective cover is tightly connected to the top surface of the protective chamber.

[0016] Based on further improvements to the above-mentioned device, the top surface of the protective chamber includes a first step plane and a second step plane connected together. The first step plane is higher than the second step plane. The Raman spectrometer is located above the first step plane in the first position. The through hole is provided on the second step plane. When the Raman spectrometer is in the second position, the protective cover plate is tightly overlapped with the second step plane.

[0017] Based on a further improvement of the above device, the mounting platform is provided with a slide rail, the slide rail is provided with a slide table, the slide table is slidably connected to the slide rail, and the turntable is rotatably disposed on the top of the slide table.

[0018] Based on a further improvement of the above device, a second motor is provided on the slide, and the turntable is connected to the rotating shaft of the second motor.

[0019] Based on further improvements to the above-mentioned device, the installation platform is provided with a first column and a second column on opposite sides, the detector is set on the first column, and the radiation source is set on the second column.

[0020] Based on further improvements to the above-mentioned device, the radiation protection shell is provided with a workpiece inlet and outlet, and the workpiece inlet and outlet are provided with an openable and closable protective door.

[0021] Compared with the prior art, the present invention can achieve at least one of the following beneficial effects:

[0022] 1. This utility model provides a multimodal detection device for non-destructive testing of special biological resources. It integrates X-ray microtomography and Raman spectroscopy, and can obtain non-intrinsic features such as equivalent atomic number, density, and structural features as well as intrinsic features such as molecular structure of the items, thereby realizing non-destructive testing of special biological resources. It can be applied to customs or other special and important places.

[0023] 2. The detection device of this utility model has two states: X-ray detection and Raman spectroscopy detection. By setting a rotating component, the Raman spectrometer can switch between a first position and a second position. When performing Raman spectroscopy detection, the Raman spectrometer moves to the first position and collects Raman spectral data of the object on the turntable. When performing X-ray detection, the Raman spectrometer moves to the second position, so that the radiation protection mechanism can protect the Raman spectrometer from X-ray radiation, thereby avoiding X-ray radiation to the Raman spectrometer.

[0024] 3. In the detection device of this utility model, a sliding structure consisting of a slide rail and a slide table is provided on the mounting platform, which facilitates the adjustment of the position of the turntable and the items on the turntable, ensuring that X-ray detection and Raman spectroscopy detection can be performed effectively.

[0025] In this invention, the above-described technical solutions can be combined with each other to achieve more preferred combinations. Other features and advantages of this invention will be set forth in the following description, and some advantages will become apparent from the description or be learned by practicing the invention. The objectives and other advantages of this invention can be realized and obtained from the description and accompanying drawings, which are particularly pointed out. Attached Figure Description

[0026] The accompanying drawings are for illustrative purposes only and are not intended to limit the scope of the invention. Throughout the drawings, the same reference numerals denote the same parts.

[0027] Figure 1 This is a schematic diagram of the structure of the detection device according to an embodiment of the present invention. Figure 1 (X-ray inspection status);

[0028] Figure 2 This is a schematic diagram of the structure of the detection device according to an embodiment of the present invention. Figure 2 (Raman detection status)

[0029] Figure label:

[0030] 1-Turntable; 2-X ...

[0031] 6-Protective chamber; 7-Protective cover; 8-Radiation protection outer shell; 9-Protective door;

[0032] 10-Mounting platform; 11-Slide rail; 12-Slide table; 13-Drive shaft; 14-First column;

[0033] 15 - Second column; 16 - Belt. Detailed Implementation

[0034] The preferred embodiments of the present invention will now be described in detail with reference to the accompanying drawings, which constitute a part of this application and are used together with the embodiments of the present invention to illustrate the principles of the present invention, but are not intended to limit the scope of the present invention.

[0035] One embodiment of this utility model discloses a detection device for detecting special biological resources, such as... Figure 1-2As shown in the diagram. The detection device includes: a radiation protection housing 8 and an installation platform 10, a turntable 1, an X-ray source 2, a detector, a Raman spectrometer 4, and a rotating assembly disposed inside the radiation protection housing 8. The turntable 1 is rotatably mounted on the installation platform 10 and is used to support the item to be detected; the X-ray source 2 and the detector are disposed opposite each other on both sides of the installation platform 10 to perform X-ray detection on the item on the turntable 1; the radiation protection housing 8 has a protective chamber 6 for X-ray protection inside; the rotating assembly includes a first motor 5 and a drive shaft 13, the shaft of the first motor 5 is connected to the drive shaft 13, and the drive shaft 13 is fixedly connected to the Raman spectrometer 4. The first motor 5 drives the Raman spectrometer 4 to switch between a first position and a second position through the drive shaft 13. In the first position, the Raman spectrometer 4 collects Raman spectral data of the target item; in the second position, the Raman spectrometer 4 is inside the protective chamber 6.

[0036] Among them, X-ray source 2 is used to emit X-rays that penetrate the object being detected, detector receives the X-rays after they have penetrated the object being detected, and generates an image based on the X-rays.

[0037] Compared with existing technologies, this utility model provides a multimodal detection device for non-destructive testing of special biological resources. It integrates X-ray microtomography and Raman spectroscopy, and can obtain non-intrinsic features such as equivalent atomic number, density, and structural characteristics as well as intrinsic features such as molecular structure, thereby realizing non-destructive testing of special biological resources. It can be applied to customs or other special and important places.

[0038] Specifically, the detection device of this invention has two states: X-ray detection and Raman spectroscopy detection. By setting a rotating component, the Raman spectrometer 4 can switch between a first position and a second position. When performing Raman spectroscopy detection, the Raman spectrometer 4 moves to the first position and collects Raman spectral data of the object on the turntable 1. When performing X-ray detection, the Raman spectrometer 4 moves to the second position, so that the radiation protection mechanism can protect the Raman spectrometer 4 from X-ray radiation, thereby preventing the Raman spectrometer 4 from being irradiated by X-rays.

[0039] Furthermore, the mounting platform 10, turntable 1, radiation source 2, detector, Raman spectrometer 4, and rotating assembly are all housed inside the radiation protection enclosure 8. By installing the radiation protection enclosure 8, operators and the surrounding environment can be protected from radiation damage, thus meeting the requirements for radiation safety and protection. In practice, the radiation protection enclosure 8 is made of lead plate material. Lead, due to its high density and excellent attenuation ability for X-rays, is widely used as an X-ray shielding material. Similarly, in practice, a protective chamber 6 can be constructed within the radiation protection enclosure 8 using lead plates.

[0040] In one embodiment, a through hole is provided on the top surface of the protective chamber 6. When the first Raman spectrometer 4 is in the first position, it is above the turntable 1. When the Raman spectrometer 4 moves from the first position to the second position, it enters the protective chamber 6 through the through hole.

[0041] In this embodiment, a through hole is provided on the top surface of the protective chamber 6, so that the Raman spectrometer 4 can be moved directly into the protective chamber 6.

[0042] Specifically, the rotating assembly includes: the first motor 5 and the drive shaft 13 disposed within the protective chamber 6, the drive shaft 13 being fixedly connected to the Raman spectrometer 4 via a connector. One end of the connector is fixedly connected to the drive shaft 13, and the other end of the connector passes through the through hole and is fixedly connected to the Raman spectrometer 4.

[0043] More specifically, the connector is an L-shaped connecting plate.

[0044] More specifically, the motor is connected to the drive shaft 13 via a belt 16 or a chain.

[0045] Specifically, a protective cover plate 7 is provided on the outer wall of the Raman spectrometer 4. When the Raman spectrometer 4 is in the second position, the protective cover plate 7 is tightly connected to the top surface of the protective chamber 6.

[0046] In this embodiment, by providing a protective cover plate 7 on the outer wall of the Raman spectrometer 4, the Raman spectrometer 4 can be completely enclosed in the protective chamber 6 when it is moved to the second position, thereby improving the protection effect.

[0047] In practice, the protective cover 7 is made of lead plate material.

[0048] Preferably, the top surface of the protective chamber 6 includes a first step plane and a second step plane connected together. The first step plane is higher than the second step plane. The Raman spectrometer 4 is located above the first step plane in the first position. The through hole is provided on the second step plane. When the Raman spectrometer 4 is in the second position, the protective cover plate 7 is tightly overlapped with the second step plane.

[0049] Specifically, by setting the top surface of the protective chamber 6 to a stepped shape, the protective cover plate 7 can completely seal the through hole on the top surface of the protective chamber 6.

[0050] In one embodiment, the mounting platform 10 is provided with a slide rail 11, the slide rail 11 is provided with a slide table, the slide table is slidably connected to the slide rail 11, and the turntable 1 is rotatably disposed on the top of the slide table.

[0051] In the detection device of this utility model, the mounting platform 10 is provided with a sliding structure consisting of a slide rail 11 and a slide table 12, which facilitates the adjustment of the position of the turntable 1 and the items on the turntable 1, and ensures that X-ray detection and Raman spectroscopy detection can be performed effectively.

[0052] Specifically, a second motor is installed on the slide table 12, and the turntable 1 is connected to the rotating shaft of the second motor. The second motor can drive the turntable 1 to rotate counterclockwise or clockwise, enabling 360° X-ray detection.

[0053] Specifically, the mounting platform 10 has a first column 14 and a second column 15 on opposite sides. The detector is mounted on the first column 14, and the radiation source 2 is mounted on the second column 15. In this embodiment, the detector and radiation source 2 are mounted by using columns.

[0054] Specifically, the radiation protection shell 8 is provided with a workpiece inlet and outlet, and the workpiece inlet and outlet are provided with an openable and closable protective door 9.

[0055] The following describes a method for detecting whether a target article contains special biological resources using the detection device of this invention. The detection method includes the following steps:

[0056] Step 1: Place the target item to be inspected on turntable 1;

[0057] Step 2: Move the Raman spectrometer 4 to the second position by rotating the assembly, so that the Raman spectrometer 4 enters the protective chamber 6;

[0058] Step 3: Turn on the X-ray source 2 and rotate the target object 360° using the turntable 1, so that the detector can collect X-ray images of the target object and collect a series of projection images of the target object at different angles; reconstruct the projection images to obtain a three-dimensional X-ray image of the target object;

[0059] Step 4: Determine whether the target item contains a target container based on the X-ray image;

[0060] Step 5: If a target container is present, remove the target container from the target item, move the Raman spectrometer 4 to the first position using the rotating assembly, and collect the Raman spectral data of the target container using the Raman spectrometer 4; determine whether there are special biological resources in the target container based on the Raman spectral data.

[0061] Step 6: If there is no target container, it is determined that there are no special biological resources in the target item, and the detection is completed.

[0062] Compared with existing technologies, the detection device of this invention, when detecting a target item, first acquires an X-ray image of the target item. Utilizing the strong penetrating power and non-destructive testing characteristics of X-ray microtomography, it analyzes the target item to determine if it contains a container. If a container is present, the target item may contain special biological resources, thus screening out items that may contain special biological resources. Then, the item is unpacked, the container is removed, and Raman spectral data of the container is acquired and analyzed to determine if the container contains special biological resources. Thus, this detection method, by performing X-ray microtomography followed by Raman spectroscopy analysis, not only accurately identifies and protects special biological resources but also avoids damage to the item.

[0063] It should be noted that, in this embodiment of the utility model, special biological resources generally require specific types of containers such as ampoules, cryovials, and glassware for storage. Therefore, by identifying whether a specific type of target container exists in the target object, items that may contain special biological resources can be screened out.

[0064] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in the present utility model should be included within the protection scope of the present utility model.

Claims

1. A detection device for special biological resources, characterized in that, The detection device includes: a radiation protection enclosure and a mounting platform, turntable, radiation source, detector, Raman spectrometer, and rotating assembly disposed inside the radiation protection enclosure. The turntable is rotatably mounted on the mounting platform and is used to carry the item to be inspected; the X-ray source and the detector are arranged opposite to each other on both sides of the mounting platform to perform X-ray inspection on the item on the turntable. The radiation protection enclosure has a protective chamber inside for X-ray protection; The rotating assembly includes a first motor and a drive shaft. The shaft of the first motor is connected to the drive shaft, and the drive shaft is fixedly connected to the Raman spectrometer. The first motor drives the Raman spectrometer to switch between a first position and a second position via the drive shaft. In the first position, the Raman spectrometer collects Raman spectral data of the target object; in the second position, the Raman spectrometer is located inside the protective chamber.

2. The detection device according to claim 1, characterized in that, The protective chamber has a through hole on its top surface. The Raman spectrometer is located above the turntable in the first position. When the Raman spectrometer moves from the first position to the second position, it enters the protective chamber through the through hole.

3. The detection device according to claim 2, characterized in that, The first motor and the drive shaft are disposed within the protective chamber, and the drive shaft is fixedly connected to the Raman spectrometer via a connector. One end of the connector is fixedly connected to the drive shaft, and the other end of the connector passes through the through hole and is fixedly connected to the Raman spectrometer.

4. The detection device according to claim 3, characterized in that, The motor is connected to the drive shaft via a belt or chain.

5. The detection device according to claim 2, characterized in that, A protective cover is provided on the outer wall of the Raman spectrometer. When the Raman spectrometer is in the second position, the protective cover is tightly connected to the top surface of the protective chamber.

6. The detection device according to claim 5, characterized in that, The top surface of the protective chamber includes a first step plane and a second step plane connected together. The first step plane is higher than the second step plane. The Raman spectrometer is located above the first step plane in the first position. The through hole is provided on the second step plane. When the Raman spectrometer is in the second position, the protective cover plate is tightly overlapped with the second step plane.

7. The detection device according to any one of claims 1-6, characterized in that, The installation platform is provided with a slide rail, and a slide table is provided on the slide rail. The slide table is slidably connected to the slide rail, and the turntable is rotatably mounted on the top of the slide table.

8. The detection device according to claim 7, characterized in that, A second motor is mounted on the slide, and the turntable is connected to the shaft of the second motor.

9. The detection device according to any one of claims 1-6, characterized in that, The installation platform has a first column and a second column on opposite sides, the detector is mounted on the first column, and the radiation source is mounted on the second column.

10. The detection device according to any one of claims 1-6, characterized in that, The radiation protection shell is provided with a workpiece inlet and outlet, and the workpiece inlet and outlet are provided with an openable and closable protective door.