Reagent tube storage box applied to nucleic acid detection reagent

Abstract

The utility model belongs to the technical field of reagent storage boxes, and mainly relates to a reagent tube storage box applied to nucleic acid detection reagents, which comprises a box body and a cover body, a sealing structure is arranged on the box body and the cover body, the sealing structure comprises a sealing strip and a sealing groove which are matched with each other, the sealing strip is arranged in the box body, and the sealing groove is arranged in the box body. The sealing groove is formed in the cover body; the sealing gasket is arranged on the box body; the tenon and the mortise are matched with each other, the tenon is arranged on the cover body, and the mortise is arranged on the box body. The sealing structure is arranged at the joint of the cover body and the box body of the storage box, and the cover body and the box body can be matched through the sealing strip, the sealing groove, the tenon and the mortise which are matched with each other, so that the cover body and the box body are combined more tightly, and a cold source placed in the box body cannot leak when a reagent is taken and placed; and the sealing performance and the heat preservation performance of the storage box are improved.

Description

TECHNICAL FIELD

[0001] The utility model belongs to reagent storage box technical field, mainly relates to a reagent tube storage box for nucleic acid detection reagent. BACKGROUND

[0002] The detection method using biological kit has very important significance in the clinical rapid diagnosis of viruses and the like. The existing method is in the form of storage box, that is, the reagent required for detection is loaded in the storage box after preparation, which is convenient for production and sales and use of detection personnel.

[0003] The prior art such as the Chinese patent with publication number CN208250315U provides a fluorescence quantitative PCR technology rapid detection of various respiratory infectious disease kit, including box body, cover, dyeing agent heat preservation layer, dyeing agent buffer wool layer, dyeing agent ice bag layer, buffer heat preservation layer, buffer ice bag layer, buffer buffer wool layer, temperature sensor, lock, temperature display, counter, counting device, the cover is hinged on the box body, the lock is located on the side of the cover and the box body not hinged, the counter and the temperature display are located on the top of the cover, the temperature sensor is located on the bottom of the cover, and the counting device is located on the bottom of the test tube groove in the box body. The utility model can store different DAPI dyeing agents and PBS buffers at different temperatures, and the number of PBS buffer test tubes in the box can be checked from the outside without opening the cover, avoiding the heat exchange between the reagents or the reagents and the external air, which causes the reagent temperature to meet the test requirements, and reduces the error of the diagnosis result.

[0004] However, the above-mentioned reagent storage box has the following problems: 1. The internal structure is complex, multiple electronic detection and display devices are provided, the cost is high, and it does not have practical production and use value; 2. The sealing and heat preservation are poor, which can easily cause the reagent to be difficult to maintain the original properties during transportation, affecting the detection accuracy. UTILITY MODEL CONTENTS

[0005] In order to solve the technical problems of poor sealing and heat preservation and complex structure of the existing reagent kit, the utility model provides a reagent tube storage box for nucleic acid detection reagent, which realizes triple sealing by setting sealing structure on the cover and the box body, improves the sealing and heat preservation of the storage box. At the same time, the storage box has simple structure, low cost and practical production and use. The specific scheme is as follows:

[0006] The utility model provides a reagent tube storage box for nucleic acid detection reagent, including box body and lid, be equipped with sealing structure on box body and lid, sealing structure includes: the sealing strip and sealing groove who match with each other, sealing strip sets up in the box body, sealing groove sets up on the lid, sealing gasket, sealing gasket sets up on the box body, the tenon and the mortise who match with each other, the tenon sets up on the lid, the mortise sets up on the box body.

[0007] Further, the box body includes an outer box and an inner box, the top of the outer box is higher than the top of the inner box, the overhanging portion is fixedly provided with the sealing strip, the top of the inner box is fixedly provided with the sealing gasket, the connecting portion of the sealing gasket and the inner box is provided with the mortise, and the top of the outer box, the sealing gasket and the top of the inner box are in a stepped shape.

[0008] Further, the lid includes an outer partition layer, a middle partition layer and an inner partition layer in a stepped shape, the sizes of the outer partition layer and the middle partition layer are matched with the outer box and the sealing gasket in sequence, the middle partition layer is provided with the sealing slot around, and the connecting portion of the middle partition layer and the inner partition layer is provided with the tenon.

[0009] Further, the middle portion of the inner box is provided with a horizontal table, the horizontal table is provided with a movable partition plate, a plurality of through holes are formed in the movable partition plate, the inner box is divided into an upper and lower layered placement area and a cold storage area by the movable partition plate, the placement area is used for placing reagents, and the cold storage area is used for placing a cold source.

[0010] Further, the material of the outer box is any one of corrugated paper and hard plastic, the material of the inner box is polyurethane foam or polystyrene foam, the material of the sealing gasket and the sealing strip is nitrile rubber, and the material of the movable partition plate is an iron sheet or a copper sheet.

[0011] Further, the lid is provided with a placement tube, the placement tube includes large tubes, middle tubes and small tubes with different diameters, and the placement tube is used for placing reagents.

[0012] Further, the material of the lid is any one of corrugated paper and hard plastic, and the material of the tenon is nitrile rubber.

[0013] Further, the storage box further includes an outer cover, and the outer cover is used for covering the lid and being tightly connected with the box body.

[0014] The utility model discloses the beneficial effect:

[0015] The general reagent needs to be stored in a -20 DEG C environment, and when the reagent needs to be used, the reagent is taken out and placed in a storage box and then transferred to an operation table for use. In order to ensure that the reagent in the storage box will not be denatured, an ice bag or ice block is generally placed in the storage box to keep the actual temperature low. The existing conventional storage box does not have sealing and heat preservation properties, and when the detection experiment operation time is long, the reagent may be denatured and inactivated.

[0016] The sealing structure is arranged at the joint of the cover body and the box body of the storage box, the cover body and the box body are matched with each other through the sealing strip and the sealing groove and the tenon and the mortise, the cover body and the box body are combined more tightly, and the cold source placed in the box body will not leak when the reagent is taken out and placed. Meanwhile, the sealing gasket is arranged on the box body, the problem that the gap between the box body and the cover body is large due to different materials is further reduced, and the sealing property of the storage box is improved. Meanwhile, the storage box provided by the utility model has a simple structure, the sealing property and the heat preservation property of the storage box can be improved without using special materials, and the storage box is suitable for large-scale industrial production and use. BRIEF DESCRIPTION OF DRAWINGS

[0017] Figure 1 is a structure schematic explosion view of a reagent tube storage box applied to nucleic acid detection reagents according to an embodiment of the utility model;

[0018] Figure 2 is a sectional view of the box body in the embodiment of the utility model;

[0019] Figure 3 is a local enlarged view of the box body in the embodiment of the utility model;

[0020] Figure 4 is a structure schematic view of the cover body in the embodiment of the utility model.

[0021] The figure mark explanation: 1, the box body; 2, the cover body; 3, the outer cover; 101, the outer box; 102, the inner box; 103, the sealing strip; 104, the sealing gasket, 105, the mortise; 106, the horizontal table; 107, the movable partition; 201, the outer partition layer; 202, the middle partition layer; 203, the inner partition layer; 204, the sealing groove; 205, the tenon; 206, the reagent tube. DETAILED DESCRIPTION

[0022] The technical scheme of the utility model will be described clearly and completely in combination with the drawings, and obviously, the described embodiments are part of the embodiments of the utility model, not all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by the ordinary skill in the art without creative labor belong to the protection scope of the utility model.

[0023] In the description of this utility model, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0024] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances. Example

[0025] The basics are as follows: Figures 1-4 As shown in the figure, this embodiment discloses a reagent tube storage box for nucleic acid detection reagents. The storage box includes an outer cover 3, a cover body 2, and a box body 1. The box body 1 is mainly used to place a cold source, such as an ice pack or ice cube. The cover body 2 is used to cover the box body 1 and place the reagent. The outer cover 3 is used to cover the cover body 2 and make tight contact with the box body 1 to achieve overall sealing of the storage box.

[0026] In this embodiment, a sealing structure is provided between the box body 1 and the lid 2, including a sealing strip 103 and a sealing groove 204 that cooperate with each other, a sealing gasket 104, and a tenon 205 and a tenon groove 105 that match each other. The sealing structure enables a tight fit between the box body 1 and the lid 2, improving the sealing and heat preservation of the storage box.

[0027] The box body 1 in the embodiment comprises an outer box 101 and an inner box 102, wherein the outer box 101 is made of corrugated paper or hard plastic to improve the overall strength of the storage box. The inner box 102 is made of polyurethane foam or polystyrene foam with heat preservation function. The inner box 102 is placed inside the outer box 101 and is bonded with the outer box 101 to achieve fixation, and the upper edge of the inner box 102 is lower than the upper edge of the outer box 101. The part of the outer box 101 that is higher than the inner box 102 is provided with a sealing strip 103, which has two upper and lower sealing strips in the embodiment. The sealing strip 103 is made of butyronitrile rubber and is fixed on the outer box 101. A sealing gasket 104 is fixed on the upper edge of the inner box 102, and the width of the sealing gasket 104 is smaller than the width of the upper edge of the inner box 102. The sealing gasket 104 is made of butyronitrile rubber. The sealing gasket 104 can reduce the gap between the cover body 2 and the box body 1 when they are closed, thereby improving the sealing performance.

[0028] In the embodiment, the upper edge of the outer shell, the sealing gasket 104 and the upper edge of the inner box 102 are in a stepped shape, which matches the structure on the cover body 2 (described later). This can strengthen the sealing effect between the cover body 2 and the box body 1. The joint between the sealing gasket 104 and the inner box 102 is provided with a mortise and tenon joint 105. In the embodiment, a total of eight mortise and tenon joints 105 are provided on the storage box.

[0029] In the embodiment, the inner box 102 is further provided with two opposite horizontal tables 106 in the middle part, and the horizontal tables 106 are in an integrated structure with the inner box 102. An active partition plate 107 is arranged above the horizontal tables 106. The active partition plate 107 is made of iron or copper with good heat conduction effect, and a plurality of through holes are arranged on the active partition plate 107. The active partition plate 107 divides the inner box 102 into an upper zone and a lower zone. The lower zone is a cold storage zone, and the upper zone is a placement zone. The cold storage zone is used to place cold sources such as ice bags or ice blocks. The placement zone is used to place reagents. The active partition plate 107 can fix the cold source and avoid shaking during movement.

[0030] In the embodiment, the cover body 2 comprises an outer partition layer 201, a middle partition layer 202 and an inner partition layer 203 in a stepped shape. The sizes of the outer partition layer 201 and the middle partition layer 202 are matched with the outer box 101 and the sealing gasket 104, respectively. The middle partition layer 202 is provided with a sealing groove 204 around the periphery. The connection part of the middle partition layer 202 and the inner partition layer 203 is provided with a tenon 205. As described above, when closed, the outer partition layer 201 covers the upper edge of the outer shell, the middle partition layer 202 covers the sealing gasket 104, and the inner partition layer 203 covers the upper edge of the inner box 102. The sealing strip 103 on the outer shell is inserted into the sealing groove 204, and the tenon 205 is inserted into the mortise and tenon joint 105, thereby achieving sealing. In the embodiment, the tenon 205 is made of butyronitrile rubber, which has elasticity and viscosity, so that the combined part is more compact.

[0031] The cover 2 is provided with a placement tube for placing reagents in the embodiment, and the opening of the placement tube is located on the upper layer of the cover 2 and extends downward. The placement tube is a single opening, and the tube body is integrally formed with the cover 2. Three types of placement tubes are provided in the embodiment, namely large, medium and small tubes with different diameters, for placing different types of reagents. The material of the cover 2 is any one of corrugated paper and hard plastic, depending on the material of the outer box 101.

[0032] The outer cover 3 is also included in the embodiment, and the material of the outer cover 3 is consistent with the outer shell and the cover 2. The outer cover 3 of the embodiment is covered on the cover 2 and is in close contact with the outer box 101.

[0033] In specific use, the cold source such as an ice bag is placed in the cold storage area, and the movable partition plate 107 is covered. The required reagents are placed in the corresponding reagent tubes 206, and then the cover 2 is covered. It is ensured that the sealing strip 103 and the tenon 205 are inserted into the sealing groove 204 and the mortise 105 respectively, so as to realize the sealing of the cover 2 and the box body 1. Finally, the outer cover 3 is covered, and the cold storage device is stored. When it is needed to use, the storage box is taken out, the outer cover 3 is opened, and the reagents can be taken and used. At this time, the cover 2 and the box body 1 are still in a sealed state, and the cold source can maintain the effect for a long time.

[0034] In summary, the sealing structure is arranged at the joint of the cover 2 and the box body 1 of the storage box, the cover 2 and the box body 1 can be combined through the mutually matched sealing strip 103 and sealing groove 204, tenon 205 and mortise 105, the cover 2 and the box body 1 are combined more closely, and it is ensured that the cold source placed in the box body 1 will not leak when the reagents are taken and placed. Meanwhile, the sealing gasket 104 is arranged on the box body 1, which can further reduce the problem of large gap between the box body 1 and the cover 2 due to the use of different materials, and improve the sealing performance of the storage box. Meanwhile, the storage box provided by the utility model has simple structure, and the sealing performance and heat preservation performance of the storage box can be improved without using special materials, which is suitable for large-scale industrial production and use.

[0035] The above is only an embodiment of the utility model, and the specific technical solutions and / or common knowledge of the scheme are not described in detail. It should be noted that, for those skilled in the art, without departing from the technical solutions of the utility model, some deformations and improvements can be made, which should be regarded as the protection scope of the utility model, and these will not affect the effect and practicability of the utility model. The protection scope of the present application should be subject to the content of the claims, and the specific implementation mode and the like in the specification can be used to explain the content of the claims.

Claims

1. A reagent tube storage box for a nucleic acid detection reagent, comprising a box body (1) and a cover body (2), characterized in that: The box body (1) and the cover body (2) are provided with a sealing structure, which comprises: A sealing strip (103) and a sealing groove (204) matched with each other, the sealing strip (103) is arranged in the box body (1), and the sealing groove (204) is arranged on the cover body (2); A sealing gasket (104) arranged on the box body (1); A tenon (205) and a mortise (105) matched with each other, the tenon (205) is arranged on the cover body (2), and the mortise (105) is arranged on the box body (1).

2. The reagent tube storage case for a nucleic acid detection reagent according to claim 1, wherein: The box body (1) comprises an outer box (101) and an inner box (102), the top of the outer box (101) is higher than the top of the inner box (102), the high part is fixedly provided with the sealing strip (103), the top of the inner box (102) is fixedly provided with the sealing gasket (104), the connecting part of the sealing gasket (104) and the inner box (102) is provided with the mortise (105), and the top of the outer box (101), the sealing gasket (104) and the top of the inner box (102) are in a stepped shape.

3. The reagent tube storage case for a nucleic acid detection reagent according to claim 1, wherein: The cover body (2) comprises an outer partition layer (201), a middle partition layer (202) and an inner partition layer (203) in a stepped shape, the sizes of the outer partition layer (201) and the middle partition layer (202) are matched with the outer box (101) and the sealing gasket (104) in sequence, the middle partition layer (202) is provided with the sealing groove (204) around, and the connecting part of the middle partition layer (202) and the inner partition layer (203) is provided with the tenon (205).

4. The reagent tube storage case for use in a nucleic acid detection reagent according to claim 2, characterized by: The middle part of the inner box (102) is provided with a horizontal table (106), the horizontal table (106) is provided with a movable partition plate (107), a plurality of through holes are formed in the movable partition plate (107), the movable partition plate (107) divides the inner box (102) into upper and lower layered placing areas and cold storage areas, the placing areas are used for placing reagents, and the cold storage areas are used for placing cold sources.

5. The reagent tube storage case for use in a nucleic acid detection reagent according to claim 4, characterized by: The material of the outer box (101) is any one of corrugated paper and hard plastic; the material of the inner box (102) is polyurethane foam or polystyrene foam; the materials of the sealing gasket (104) and the sealing strip (103) are nitrile rubber; and the material of the movable partition plate (107) is an iron sheet or a copper sheet.

6. The reagent tube storage case for use in a nucleic acid detection reagent according to claim 3, wherein: The material of the cover body (2) is any one of corrugated paper and hard plastic; and the material of the tenon (205) is nitrile rubber.

7. The reagent tube storage case for use in a nucleic acid detection reagent according to claim 1, characterized by: The storage box further comprises an outer cover (3), and the outer cover (3) is used for covering the cover body (2) and being tightly connected with the box body (1).

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