Cell culture fluid sampler
By designing a cell culture medium sampler with through holes in different directions, the problem of easy contamination in traditional sampling methods was solved, achieving sample purity and operational flexibility, and ensuring the purity of cell culture medium and the reliability of experiments.
Patent Information
- Application Number
- CN202520346800.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-02-28
- Publication Date
- 2026-02-27
- Estimated Expiration
- 2035-02-28
AI Technical Summary
Traditional cell culture medium sampling methods are susceptible to external contamination, leading to biased or failed experimental results.
A cell culture medium sampler was designed, which uses a cover with through holes arranged in different directions. The internal pressure is controlled by a pressing part to switch between sample preservation and temporary storage states, thereby reducing the entry of external contaminants.
It improves sample purity, reduces the risk of external contaminants entering, and enhances operational flexibility and convenience.
Smart Images
Figure CN223951020U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to cell sampling technical field especially relates to a cell culture solution sampler. BACKGROUND
[0002] Cell culture is a key step in biomedical research and biopharmaceutical production. In order to monitor the growth state of cells, metabolic activity and detect possible contamination, it is necessary to take a small amount of culture medium from the culture environment for analysis regularly. Traditional sampling methods include manual suction, use of pipettes or direct pouring, etc. However, these methods have many inconveniences and potential risks in actual operation, and are easy to introduce external pollutants. Especially when operating in an open environment, the introduction of any external microorganisms, chemicals or particulate matter can lead to deviation of experimental results, and even cause the failure of the entire culture batch. SUMMARY
[0003] In view of the deficiencies in the prior art, the utility model provides a cell culture solution sampler, which solves the technical problem of easy contamination of cell sampling samples in the prior art.
[0004] According to the embodiments of the utility model, the following technical scheme is adopted:
[0005] A cell culture solution sampler comprises:
[0006] The sampling tube body has an upper end and a lower end, and the upper end and the lower end of the sampling tube body are respectively provided with a pressing part and a sampling part. The pressing part is made of elastic material and is used to press or release to change the pressure state inside the sampling tube body.
[0007] The cover body comprises a first through hole arranged in a first direction and a second through hole arranged in a second direction. The first through hole and the second through hole are in communication or not in communication, and the sampling part can be selectively inserted into one of the first through hole and the second through hole to be configured as a storage state or a temporary storage state.
[0008] The first direction and the second direction are two different directions.
[0009] Preferably, the first direction is the axial direction of the cover body, and the second direction is the radial direction of the cover body.
[0010] Preferably, the surface of the cover body is provided with a plurality of support surfaces at intervals, and one of the plurality of support surfaces is arranged opposite to the second through hole.
[0011] Preferably, the support surface is a plane for supporting the cover body.
[0012] Preferably, a connecting section is formed between two adjacent support surfaces, and the connecting section is provided with a chamfer structure.
[0013] Preferably, the surface of the cover is provided with a notch, and opposite ends of the notch are defined as a first end and a second end.
[0014] Preferably, the width of the notch gradually increases from the first end to the second end of the notch.
[0015] Preferably, the width of the second end of the notch is L, the diameter of the second through hole is d, and L and d satisfy L < d.
[0016] Preferably, the first through hole and the second through hole are provided with a flange.
[0017] Compared with the prior art, the utility model has the following beneficial effects: 1. By designing the cover with two through holes arranged in different directions, the sampling part can be selectively inserted in different operating states, which helps to reduce the risk of external pollutants entering the inside of the sampling tube during sampling, and ensures the purity of the sample; 2. The first through hole and the second through hole of the cover can be selected to be communicated or not as required, which facilitates short-term storage or long-term preservation, and improves the flexibility and convenience of use. BRIEF DESCRIPTION OF DRAWINGS
[0018] Figure 1 Fig. 1 is a structural schematic view of a sampler in an embodiment of the utility model;
[0019] Figure 2 Fig. 3 is a structural schematic view of a cover in an embodiment of the utility model.
[0020] In the above drawings: 1, pressing part; 2, sampling part; 3, cover; 301, first through hole; 302, second through hole; 4, support surface; 5, connecting section; 6, flange; 7, notch. DETAILED DESCRIPTION
[0021] In order to make the purpose, technical scheme and beneficial effects of the utility model clearer, the technical scheme of the utility model is further described below with reference to the drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the utility model, and are not used to limit the utility model.
[0022] Referring to Figures 1-2 The utility model provides a kind of cell culture fluid sampler, comprising:
[0023] The sampling tube body has an upper end and a lower end, and the upper end and the lower end of the sampling tube body are respectively provided with a pressing part 1 and a sampling part 2, the pressing part 1 is made of elastic material, and is used to press or release the pressure state in the sampling tube body;
[0024] The cover body 3 includes a first through hole 301 arranged in a first direction and a second through hole 302 arranged in a second direction, the first through hole 301 and the second through hole 302 are in communication or not in communication, and the sampling part 2 can be selectively inserted into one of the first through hole 301 and the second through hole 302 to be configured as a storage state or a temporary storage state;
[0025] The first direction and the second direction are two different directions.
[0026] In this embodiment, the sampling tube body has an upper end and a lower end, the upper end is provided with a pressing part 1 made of elastic material, which is used to change the pressure state in the sampling tube body by pressing or releasing, thereby controlling the entry and exit of liquid, and the lower end is a sampling part 2 responsible for directly contacting and collecting cell culture liquid samples, the cover body 3 is provided with two through holes arranged in different directions, the first through hole 301 is arranged in a first direction, and the second through hole 302 is arranged in a second direction, and the two directions are different, the first through hole 301 and the second through hole 302 can be in communication or not in communication, depending on the use requirement, the sampling part 2 can be selectively inserted into any one of the first through hole 301 or the second through hole 302 to realize the storage state or the temporary storage state, by selectively inserting the sampling part 2 into different holes, the user can switch between the storage state and the temporary storage state, increasing the flexibility and practicality of the device, since the design takes into account the different direction holes and the optional connection mode, which helps to reduce the risk of sample contamination by the outside world during sampling, ensuring the purity of the sample.
[0027] The first direction is the axial direction of the cover body 3, and the second direction is the radial direction of the cover body 3.
[0028] In this embodiment, by arranging the first through hole 301 in the axial direction, it can be directly connected to the sampling tube body, ensuring that the fluid can enter or leave the sampler in the shortest path, reducing the possible pollution risk and improving the operation efficiency, the second through hole 302 is arranged in the radial direction, providing another fluid processing mode, so that the sampler can flexibly switch between different working modes (such as storage state or temporary storage state) according to experimental requirements, and the sampling part 2 can be selectively inserted into the first through hole 301 or the second through hole 302 by a simple insertion action, thereby quickly adjusting the working state of the sampler.
[0029] The surface of the cover 3 is provided with a plurality of support surfaces 4 at intervals, one of the plurality of support surfaces 4 is arranged opposite to the second through hole 302. Further, the support surface 4 is a plane for supporting the cover 3.
[0030] In this embodiment, the design of the support surface 4 can provide additional stability when the sampler is placed, prevent the sampler from rolling or sliding, and ensure that it remains stable. By arranging one support surface 4 opposite to the second through hole 302, the second through hole 302 can be more easily identified and positioned during operation, which is particularly useful for operations that require frequent switching between the saved state and the temporary state, reducing the likelihood of misoperation.
[0031] A connecting section 5 is formed between adjacent two support surfaces 4, and the connecting section 5 is provided with a chamfer structure.
[0032] In this embodiment, a connecting section 5 with a chamfer structure is formed between adjacent support surfaces 4, and the combined action of each flat support surface 4 and the chamfer structure allows the sampler to be placed stably and easily operated, while reducing the likelihood of accidental movement or overturning.
[0033] The surface of the cover 3 is provided with a notch 7, and the opposite ends of the notch 7 are defined as a first end and a second end. The first end of the notch 7 extends to the end face of the cover 3, and the second end of the notch 7 is in communication with the second through hole 302. Further, the width of the notch 7 gradually increases from the first end of the notch 7 to the direction of the second end.
[0034] In this embodiment, the surface of the cover 3 is provided with a notch 7, which has two functions. One is to break part of the cover 3, and when the sampling part 2 is inserted into the first through hole 301, the notch 7 can plastically deform to increase the aperture of the second through hole 302, facilitating the insertion of the sampling part 2 (see Figure 1 The sampling part 2 is a conical structure), and the second function is to increase the aperture of the second through hole 302, facilitating the insertion of the sampling part 2 into the second through hole 302.
[0035] The width of the second end of the notch 7 is L, and the diameter of the second through hole 302 is d, and L and d satisfy L < d.
[0036] In this embodiment, in order to avoid the situation that the sampling part 2 is tilted towards the second end or separated from the second through hole 302, the width of the second end of the notch 7 is L, the diameter of the second through hole 302 is d, and L and d satisfy L < d.
[0037] The first through hole 301 and the second through hole 302 are provided with a flange 6.
[0038] In this embodiment, only the flange 6 of the first through hole 301 is shown, the purpose is to increase the friction with the tube body, and to avoid a small amount of culture solution in the cover body 3 from flowing into the first through hole 301 from the second through hole 302, and flowing out through the second through hole 302, causing pollution. If not connected, the culture solution will not overflow, and the flange 6 at this time is used to increase friction.
[0039] Finally, it should be pointed out that the above embodiments are only used to illustrate the technical solutions of the present application and are not limiting. Although the present application has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that the technical solutions of the present application can be modified or replaced by equivalents without departing from the purpose and scope of the technical solutions of the present application, and they should be covered in the scope of the claims of the present application.
Claims
1. A cell culture fluid sampler, comprising: The utility model relates to a sampling tube and a cover body thereof, and belongs to the technical field of sampling tubes. The sampling tube comprises a sampling tube body having an upper end and a lower end, wherein the upper end and the lower end of the sampling tube body are respectively provided with a pressing part and a sampling part. The pressing part is made of elastic material and is used to press or release the pressure state inside the sampling tube body. The cover body comprises a first through hole arranged in a first direction and a second through hole arranged in a second direction.
2. A cell culture fluid sampler as defined in claim 1, wherein, The first through hole and the second through hole are in communication or not in communication, and the sampling part can be selectively inserted into one of the first through hole and the second through hole to be configured as a storage state or a temporary storage state.
3. A cell culture fluid sampler as defined in claim 2, wherein, The first direction and the second direction are two different directions.
4. A cell culture fluid sampler as defined in claim 3, wherein, The first direction is the axial direction of the cover body, and the second direction is the radial direction of the cover body.
5. A cell culture fluid sampler as defined in claim 4, wherein, The surface of the cover body is provided with a plurality of support surfaces at intervals.
6. A cell culture fluid sampler as claimed in any one of claims 2 to 5, wherein, One of the plurality of support surfaces is oppositely arranged with the second through hole.
7. A cell culture fluid sampler as defined in claim 6, wherein, The support surface is a plane and is used to support the cover body.
8. A cell culture fluid sampler as defined in claim 7, wherein, Adjacent two support surfaces form a connecting section, and the connecting section is provided with a chamfer structure.
9. A cell culture fluid sampler as defined in claim 1, wherein, The surface of the cover body is provided with a notch. The opposite ends defining the notch are a first end and a second end. The first end of the notch extends to the end face of the cover body, and the second end of the notch is in communication with the second through hole. From the first end of the notch to the second end of the notch, the width of the notch gradually increases. The width of the second end of the notch is L, and the diameter of the second through hole is d. L and d satisfy L < d. The first through hole and / or the second through hole is provided with a flange.